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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for E4F1

Z-value: 0.43

Motif logo

Transcription factors associated with E4F1

Gene Symbol Gene ID Gene Info
ENSG00000167967.16 E4F1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E4F1hg38_v1_chr16_+_2223555_22236360.331.1e-01Click!

Activity profile of E4F1 motif

Sorted Z-values of E4F1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of E4F1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_+_32844789 1.99 ENST00000414474.5
proteasome 20S subunit beta 9
chr6_-_29628038 1.92 ENST00000355973.7
ENST00000377012.8
gamma-aminobutyric acid type B receptor subunit 1
chr19_+_45001430 1.10 ENST00000625761.2
ENST00000505236.1
ENST00000221452.13
RELB proto-oncogene, NF-kB subunit
chr6_-_32844643 0.66 ENST00000374881.3
proteasome 20S subunit beta 8
chr11_-_77474041 0.60 ENST00000278568.8
p21 (RAC1) activated kinase 1
chr10_+_132537814 0.59 ENST00000368593.7
inositol polyphosphate-5-phosphatase A
chr6_-_34696733 0.52 ENST00000374023.8
inflammation and lipid regulator with UBA-like and NBR1-like domains
chr6_-_34696839 0.49 ENST00000374026.7
inflammation and lipid regulator with UBA-like and NBR1-like domains
chr2_-_60553558 0.49 ENST00000642439.1
ENST00000356842.9
BAF chromatin remodeling complex subunit BCL11A
chr18_+_26226417 0.48 ENST00000269142.10
TATA-box binding protein associated factor 4b
chr2_-_60553409 0.46 ENST00000358510.6
ENST00000643004.1
BAF chromatin remodeling complex subunit BCL11A
chr6_+_63572472 0.39 ENST00000370651.7
ENST00000626021.3
novel protein
protein tyrosine phosphatase 4A1
chr18_+_26226472 0.39 ENST00000578121.5
TATA-box binding protein associated factor 4b
chr1_-_16156059 0.36 ENST00000358432.8
EPH receptor A2
chr17_-_38674940 0.35 ENST00000621654.2
elongin BC and polycomb repressive complex 2 associated protein
chr6_+_26204552 0.35 ENST00000615164.2
H4 clustered histone 5
chr10_+_132537778 0.35 ENST00000368594.8
inositol polyphosphate-5-phosphatase A
chr19_+_33796268 0.34 ENST00000587559.5
ENST00000588637.5
potassium channel tetramerization domain containing 15
chr11_-_1572261 0.34 ENST00000397374.8
dual specificity phosphatase 8
chr20_+_59604527 0.34 ENST00000371015.6
phosphatase and actin regulator 3
chr20_+_34704336 0.33 ENST00000374809.6
ENST00000374810.8
ENST00000451665.5
tumor protein p53 inducible nuclear protein 2
chr5_-_95961830 0.33 ENST00000513343.1
ENST00000237853.9
elongation factor for RNA polymerase II 2
chr14_-_22919124 0.31 ENST00000555209.5
ENST00000554256.5
ENST00000557403.5
ENST00000359890.8
ENST00000557549.5
ENST00000555676.5
ENST00000557571.5
ENST00000557464.5
ENST00000554618.5
ENST00000556862.5
ENST00000555722.5
ENST00000346528.9
ENST00000542016.6
ENST00000399922.6
ENST00000557227.5
RNA binding motif protein 23
chr6_-_3157536 0.31 ENST00000333628.4
tubulin beta 2A class IIa
chrX_-_153971810 0.31 ENST00000310441.12
host cell factor C1
chr22_+_38705922 0.30 ENST00000216044.10
GTP binding protein 1
chr14_+_58637934 0.29 ENST00000395153.8
dishevelled binding antagonist of beta catenin 1
chr3_-_108222362 0.26 ENST00000492106.1
intraflagellar transport 57
chr20_+_34558706 0.26 ENST00000360668.8
ENST00000397709.1
microtubule associated protein 1 light chain 3 alpha
chr2_-_60553618 0.25 ENST00000643716.1
ENST00000359629.10
ENST00000642384.2
ENST00000335712.11
BAF chromatin remodeling complex subunit BCL11A
chrX_-_84502442 0.25 ENST00000297977.9
ENST00000506585.6
ENST00000373177.3
ENST00000449553.2
highly divergent homeobox
chr7_-_140924699 0.24 ENST00000288602.11
ENST00000469930.2
ENST00000496384.7
B-Raf proto-oncogene, serine/threonine kinase
chr4_-_110636963 0.24 ENST00000394595.8
paired like homeodomain 2
chr19_+_3506251 0.24 ENST00000441788.7
fizzy and cell division cycle 20 related 1
chr19_+_52190006 0.24 ENST00000454220.6
ENST00000322088.11
ENST00000477989.1
ENST00000628959.1
protein phosphatase 2 scaffold subunit Aalpha
chr11_-_77474087 0.23 ENST00000356341.8
p21 (RAC1) activated kinase 1
chr7_-_140924900 0.23 ENST00000646891.1
ENST00000644969.2
B-Raf proto-oncogene, serine/threonine kinase
chr1_+_85062304 0.22 ENST00000326813.12
ENST00000528899.5
ENST00000294664.11
dynein axonemal intermediate chain 3
chr8_+_93916882 0.22 ENST00000297598.5
ENST00000520728.5
ENST00000518107.5
ENST00000396200.3
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr15_-_40755223 0.21 ENST00000560460.5
ENST00000338376.8
ENST00000560905.1
regulator of microtubule dynamics 3
chr20_+_45791978 0.21 ENST00000449078.5
ENST00000456939.5
deoxynucleotidyltransferase terminal interacting protein 1
chr20_+_45791930 0.20 ENST00000372622.8
deoxynucleotidyltransferase terminal interacting protein 1
chr12_-_93441886 0.19 ENST00000552442.1
ENST00000550657.1
ENST00000318066.7
ubiquitin conjugating enzyme E2 N
chr12_+_53985138 0.19 ENST00000303460.5
homeobox C10
chr22_+_17638796 0.18 ENST00000355028.4
BCL2 like 13
chr19_+_3506355 0.18 ENST00000652521.1
fizzy and cell division cycle 20 related 1
chr3_+_38165484 0.17 ENST00000446845.5
ENST00000311806.8
oxidative stress responsive kinase 1
chr4_-_75673360 0.17 ENST00000676584.1
ENST00000678329.1
ENST00000677889.1
ENST00000357854.7
ENST00000359707.9
ENST00000676974.1
ENST00000678273.1
ENST00000677201.1
ENST00000678244.1
ENST00000677125.1
ENST00000677162.1
G3BP stress granule assembly factor 2
chr19_+_1941118 0.17 ENST00000255641.13
casein kinase 1 gamma 2
chr19_-_45584810 0.16 ENST00000323060.3
outer mitochondrial membrane lipid metabolism regulator OPA3
chr4_-_75673139 0.16 ENST00000677566.1
ENST00000503660.5
ENST00000677060.1
ENST00000678552.1
G3BP stress granule assembly factor 2
chr16_-_3717505 0.16 ENST00000538171.5
ENST00000246957.10
TNF receptor associated protein 1
chr22_+_17638584 0.15 ENST00000337612.9
ENST00000418951.6
ENST00000538149.5
ENST00000543133.5
ENST00000611738.4
ENST00000616863.4
ENST00000618481.4
ENST00000317582.10
ENST00000493680.5
BCL2 like 13
chr11_+_66421004 0.15 ENST00000639555.1
ENST00000311034.7
neuronal PAS domain protein 4
chr8_-_94262308 0.15 ENST00000297596.3
ENST00000396194.6
GTP binding protein overexpressed in skeletal muscle
chr19_-_10231293 0.15 ENST00000646641.1
sphingosine-1-phosphate receptor 2
chr19_+_42076129 0.15 ENST00000359044.5
zinc finger protein 574
chr2_-_75199511 0.15 ENST00000305249.10
tachykinin receptor 1
chr14_+_94026314 0.14 ENST00000203664.10
ENST00000553723.1
OTU deubiquitinase, ubiquitin aldehyde binding 2
chr1_-_214551556 0.14 ENST00000366956.10
protein tyrosine phosphatase non-receptor type 14
chr1_+_2073986 0.13 ENST00000461106.6
protein kinase C zeta
chr6_+_47477731 0.13 ENST00000359314.5
CD2 associated protein
chr17_+_73164977 0.13 ENST00000580671.1
ENST00000357585.4
novel transcript
somatostatin receptor 2
chr6_+_30061231 0.13 ENST00000376782.6
ENST00000359374.8
ENST00000376785.2
ENST00000332435.10
RNA polymerase I subunit H
chr2_+_218880844 0.13 ENST00000258411.8
Wnt family member 10A
chr6_-_162727748 0.12 ENST00000366892.5
ENST00000366898.6
ENST00000366897.5
ENST00000366896.5
ENST00000674250.1
parkin RBR E3 ubiquitin protein ligase
chr2_-_73293538 0.12 ENST00000436467.4
ENST00000545030.1
early growth response 4
chr1_+_63322558 0.12 ENST00000371116.4
forkhead box D3
chr19_+_35641728 0.11 ENST00000619399.4
ENST00000379026.6
ENST00000379023.8
ENST00000402764.6
ENST00000479824.5
ETS variant transcription factor 2
chr5_-_133612524 0.11 ENST00000265342.12
follistatin like 4
chr2_+_74958635 0.11 ENST00000483063.2
DNA polymerase epsilon 4, accessory subunit
chr11_-_31817904 0.11 ENST00000423822.7
paired box 6
chr6_+_109978297 0.11 ENST00000275169.5
G protein-coupled receptor 6
chr17_+_7572818 0.11 ENST00000293831.13
ENST00000582169.5
ENST00000578754.5
ENST00000578495.5
ENST00000585024.5
ENST00000583802.5
ENST00000577269.5
ENST00000584784.5
ENST00000582746.5
ENST00000581621.1
eukaryotic translation initiation factor 4A1
novel transcript
chr17_-_42388467 0.11 ENST00000678792.1
ENST00000679166.1
ENST00000677442.1
ENST00000677723.1
ENST00000678905.1
ENST00000677479.1
ENST00000678043.1
ENST00000677152.1
ENST00000677603.1
ENST00000588969.5
ENST00000678535.1
ENST00000679185.1
ENST00000677030.1
ENST00000679014.1
ENST00000678044.1
ENST00000678827.1
signal transducer and activator of transcription 3
chr3_+_185586270 0.10 ENST00000296257.10
SUMO specific peptidase 2
chr2_-_61888570 0.10 ENST00000394440.8
ENST00000544079.2
chaperonin containing TCP1 subunit 4
chr6_+_7389774 0.10 ENST00000379834.7
RIO kinase 1
chr17_-_42388360 0.10 ENST00000678960.1
ENST00000404395.3
ENST00000389272.7
ENST00000677421.1
ENST00000585517.5
ENST00000264657.10
ENST00000678048.1
ENST00000678674.1
ENST00000678913.1
ENST00000678572.1
ENST00000678906.1
signal transducer and activator of transcription 3
chr6_+_109978256 0.10 ENST00000414000.3
G protein-coupled receptor 6
chr16_+_27550127 0.09 ENST00000261588.9
katanin interacting protein
chr3_+_184335906 0.09 ENST00000450976.5
ENST00000418281.5
ENST00000340957.9
ENST00000433578.5
family with sequence similarity 131 member A
chr1_-_31644866 0.09 ENST00000373703.5
penta-EF-hand domain containing 1
chr17_+_45132600 0.09 ENST00000619916.4
ENST00000431281.5
ENST00000591859.5
acyl-CoA binding domain containing 4
chr17_+_18183803 0.09 ENST00000399138.5
alkB homolog 5, RNA demethylase
chr6_-_7389709 0.08 ENST00000296742.11
ENST00000502583.6
cancer antigen 1
chr7_-_100428657 0.08 ENST00000360951.8
ENST00000398027.6
ENST00000684423.1
ENST00000472716.1
zinc finger CW-type and PWWP domain containing 1
chr6_-_53348902 0.08 ENST00000370913.5
ENST00000304434.11
ELOVL fatty acid elongase 5
chr11_-_33161461 0.08 ENST00000323959.9
ENST00000431742.2
ENST00000524827.6
cleavage stimulation factor subunit 3
chr11_+_67606894 0.08 ENST00000532303.5
ENST00000532244.5
ENST00000528328.1
ENST00000322776.11
ENST00000529927.5
ENST00000532343.5
ENST00000415352.6
ENST00000533075.5
ENST00000529867.5
ENST00000530638.1
NADH:ubiquinone oxidoreductase core subunit V1
chr1_+_180230257 0.08 ENST00000263726.4
LIM homeobox 4
chr10_+_117241107 0.08 ENST00000644641.2
solute carrier family 18 member A2
chr3_-_108222383 0.08 ENST00000264538.4
intraflagellar transport 57
chr5_-_32444722 0.08 ENST00000265069.13
zinc finger RNA binding protein
chr6_+_162727941 0.08 ENST00000366888.6
parkin coregulated
chr17_+_782340 0.08 ENST00000304478.9
mitochondrial rRNA methyltransferase 3
chr1_+_26169891 0.07 ENST00000374266.7
ENST00000270812.6
zinc finger protein 593
chr19_+_13747887 0.07 ENST00000221554.13
ENST00000586666.5
coiled-coil domain containing 130
chr22_-_43862480 0.07 ENST00000330884.9
sulfotransferase family 4A member 1
chr1_-_70354673 0.07 ENST00000370944.9
ENST00000262346.6
ankyrin repeat domain 13C
chr10_-_133308844 0.07 ENST00000682905.1
ENST00000682515.1
ENST00000683612.1
ENST00000252936.8
ENST00000417178.7
ENST00000682161.1
ENST00000683014.1
ENST00000683060.1
ENST00000683383.1
tubulin gamma complex associated protein 2
chr2_+_10044175 0.07 ENST00000440320.5
ENST00000535335.1
Kruppel like factor 11
chr4_+_74445302 0.06 ENST00000502307.1
amphiregulin
chr16_+_29900474 0.06 ENST00000308748.10
aspartate beta-hydroxylase domain containing 1
chr10_-_49762276 0.06 ENST00000374103.9
oxoglutarate dehydrogenase L
chr20_-_45791865 0.06 ENST00000243938.9
WAP four-disulfide core domain 3
chr20_+_35615812 0.06 ENST00000679710.1
ENST00000374273.8
sperm associated antigen 4
chr11_-_3797490 0.05 ENST00000397004.8
ENST00000397007.8
ENST00000532475.1
ENST00000324932.12
nucleoporin 98 and 96 precursor
chr4_-_67701113 0.05 ENST00000420827.2
ENST00000322244.10
ubiquitin like modifier activating enzyme 6
chr1_-_244863085 0.05 ENST00000440865.2
heterogeneous nuclear ribonucleoprotein U
chr10_+_63133247 0.05 ENST00000435510.6
nuclear receptor binding factor 2
chr20_+_5911501 0.05 ENST00000378961.9
ENST00000455042.1
chromogranin B
chr11_-_31817937 0.05 ENST00000638965.1
ENST00000241001.13
ENST00000638914.3
ENST00000379132.8
ENST00000379129.7
paired box 6
chr2_-_240025299 0.04 ENST00000404554.5
ENST00000407129.3
ENST00000307300.8
ENST00000678455.1
ENST00000444548.6
ENST00000252711.7
ENST00000620965.5
ENST00000443626.5
NADH:ubiquinone oxidoreductase subunit A10
chr17_+_41688879 0.04 ENST00000469257.2
ENST00000591776.5
eukaryotic translation initiation factor 1
chr18_+_33578213 0.04 ENST00000681521.1
ENST00000269197.12
ASXL transcriptional regulator 3
chr11_+_66291887 0.04 ENST00000327259.5
transmembrane protein 151A
chr8_-_97277890 0.04 ENST00000322128.5
TSPY like 5
chr9_-_128881922 0.04 ENST00000320665.10
ENST00000436267.7
ENST00000302586.8
ENST00000651925.1
kynurenine aminotransferase 1
kynurenine aminotransferase 1
chr12_+_106774630 0.03 ENST00000392839.6
ENST00000548914.5
ENST00000355478.6
ENST00000552619.1
ENST00000549643.5
ENST00000392837.9
RIC8 guanine nucleotide exchange factor B
chr19_-_29213110 0.03 ENST00000304863.6
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr16_-_46748337 0.03 ENST00000394809.9
myosin light chain kinase 3
chr10_-_49762335 0.03 ENST00000419399.4
ENST00000432695.2
oxoglutarate dehydrogenase L
chr10_-_133308817 0.03 ENST00000543663.6
tubulin gamma complex associated protein 2
chr12_-_84911178 0.03 ENST00000681688.1
solute carrier family 6 member 15
chr3_-_185938006 0.03 ENST00000342294.4
ENST00000453386.7
ENST00000382191.4
transformer 2 beta homolog
chr3_-_101677119 0.02 ENST00000312938.5
zinc finger and BTB domain containing 11
chr19_-_58555085 0.02 ENST00000312547.7
charged multivesicular body protein 2A
chr10_+_63133279 0.02 ENST00000277746.11
nuclear receptor binding factor 2
chr19_-_58554960 0.02 ENST00000596708.1
ENST00000601220.5
ENST00000597848.1
charged multivesicular body protein 2A
chr16_-_46973634 0.02 ENST00000317089.10
DnaJ heat shock protein family (Hsp40) member A2
chr9_-_96619378 0.02 ENST00000375240.7
ENST00000463569.5
cell division cycle 14B
chr19_-_45584769 0.02 ENST00000263275.5
outer mitochondrial membrane lipid metabolism regulator OPA3
chr6_-_144095556 0.02 ENST00000367569.4
splicing factor 3b subunit 5
chr6_+_75749272 0.02 ENST00000653423.1
myosin VI
chr2_+_219544002 0.02 ENST00000421791.1
ENST00000373883.4
ENST00000451952.1
transmembrane protein 198
chr17_-_782253 0.02 ENST00000628529.2
ENST00000625892.1
ENST00000301328.9
ENST00000576419.1
glyoxalase domain containing 4
chr10_-_117375407 0.01 ENST00000334464.7
PDZ domain containing 8
chr11_-_3797458 0.01 ENST00000355260.7
nucleoporin 98 and 96 precursor
chr14_+_60249191 0.01 ENST00000395076.9
protein phosphatase, Mg2+/Mn2+ dependent 1A
chr11_-_6612141 0.01 ENST00000527248.2
ENST00000299424.9
TATA-box binding protein associated factor 10
chr17_-_782317 0.00 ENST00000301329.10
glyoxalase domain containing 4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:1903860 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.1 0.4 GO:0048320 notochord formation(GO:0014028) axial mesoderm formation(GO:0048320) negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.3 GO:0019046 release from viral latency(GO:0019046)
0.1 0.8 GO:0061052 negative regulation of cell proliferation involved in contact inhibition(GO:0060244) negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.1 0.2 GO:0060460 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung morphogenesis(GO:0060460) superior vena cava morphogenesis(GO:0060578)
0.1 0.2 GO:1903537 meiotic spindle elongation(GO:0051232) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.1 0.5 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.2 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.1 0.3 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.1 1.1 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 0.2 GO:0009386 translational attenuation(GO:0009386)
0.0 0.3 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.2 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0 0.9 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.0 1.9 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.1 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.1 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.1 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.1 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 2.6 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.3 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.1 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.1 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.1 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.9 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.3 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.1 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
0.0 0.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.4 GO:0090344 negative regulation of cell aging(GO:0090344)
0.0 0.1 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.0 GO:1903722 regulation of centriole elongation(GO:1903722)
0.0 0.2 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.0 0.1 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.3 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.0 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.3 2.6 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 1.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.2 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 0.3 GO:0070449 elongin complex(GO:0070449)
0.0 0.3 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.8 GO:0071437 invadopodium(GO:0071437)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.3 GO:0044754 autolysosome(GO:0044754)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797) Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.9 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 2.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.9 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) PH domain binding(GO:0042731)
0.1 0.9 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.4 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.3 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.3 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.1 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.5 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.4 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.3 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.3 PID IL12 2PATHWAY IL12-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 2.6 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.8 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.7 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.9 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling