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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for EMX1

Z-value: 0.52

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Transcription factors associated with EMX1

Gene Symbol Gene ID Gene Info
ENSG00000135638.14 EMX1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EMX1hg38_v1_chr2_+_72917489_72917525,
hg38_v1_chr2_+_72916183_72916260
0.311.3e-01Click!

Activity profile of EMX1 motif

Sorted Z-values of EMX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of EMX1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr4_-_76023489 0.61 ENST00000306602.3
C-X-C motif chemokine ligand 10
chr4_+_94995919 0.61 ENST00000509540.6
bone morphogenetic protein receptor type 1B
chr6_+_29111560 0.54 ENST00000377169.2
olfactory receptor family 2 subfamily J member 3
chr21_-_30881572 0.51 ENST00000332378.6
keratin associated protein 11-1
chr3_+_98149326 0.50 ENST00000437310.1
olfactory receptor family 5 subfamily H member 14
chr10_-_49762335 0.48 ENST00000419399.4
ENST00000432695.2
oxoglutarate dehydrogenase L
chr6_-_169250825 0.47 ENST00000676869.1
ENST00000676760.1
thrombospondin 2
chr3_+_42979281 0.47 ENST00000488863.5
ENST00000430121.3
golgi associated kinase 1A
chr3_-_142029108 0.47 ENST00000497579.5
transcription factor Dp-2
chr10_-_49762276 0.46 ENST00000374103.9
oxoglutarate dehydrogenase L
chr15_+_76336755 0.45 ENST00000290759.9
ISL LIM homeobox 2
chr20_-_51802433 0.43 ENST00000395997.3
spalt like transcription factor 4
chr12_+_26195647 0.41 ENST00000535504.1
sarcospan
chr7_-_93148345 0.40 ENST00000437805.5
ENST00000446959.5
ENST00000439952.5
ENST00000414791.5
ENST00000446033.1
ENST00000411955.5
ENST00000318238.9
sterile alpha motif domain containing 9 like
chr5_-_151093566 0.39 ENST00000521001.1
TNFAIP3 interacting protein 1
chr4_+_85604146 0.38 ENST00000512201.5
Rho GTPase activating protein 24
chr8_+_49911396 0.37 ENST00000642720.2
syntrophin gamma 1
chr4_+_94996232 0.36 ENST00000512312.5
bone morphogenetic protein receptor type 1B
chr7_-_73624492 0.36 ENST00000414749.6
ENST00000429400.6
ENST00000434326.5
ENST00000313375.8
ENST00000354613.5
ENST00000453275.1
MLX interacting protein like
chr8_+_49911604 0.36 ENST00000642164.1
ENST00000644093.1
ENST00000643999.1
ENST00000647073.1
ENST00000646880.1
syntrophin gamma 1
chr6_-_52840843 0.36 ENST00000370989.6
glutathione S-transferase alpha 5
chr10_-_114144599 0.36 ENST00000428953.1
coiled-coil domain containing 186
chr9_-_16728165 0.36 ENST00000603713.5
ENST00000603313.5
basonuclin 2
chr11_-_117877463 0.36 ENST00000527717.5
FXYD domain containing ion transport regulator 6
chr12_+_80716906 0.35 ENST00000228644.4
myogenic factor 5
chr6_-_49713564 0.35 ENST00000616725.4
ENST00000618917.4
cysteine rich secretory protein 2
chr6_-_49713521 0.35 ENST00000339139.5
cysteine rich secretory protein 2
chr11_-_117876719 0.34 ENST00000529335.6
ENST00000260282.8
FXYD domain containing ion transport regulator 6
chr17_-_41149823 0.33 ENST00000343246.6
keratin associated protein 4-5
chr8_+_22567038 0.33 ENST00000523348.1
sorbin and SH3 domain containing 3
chr11_-_117876892 0.33 ENST00000539526.5
FXYD domain containing ion transport regulator 6
chr8_-_42377227 0.33 ENST00000220812.3
dickkopf WNT signaling pathway inhibitor 4
chr20_+_61599755 0.32 ENST00000543233.2
cadherin 4
chr11_+_92969651 0.31 ENST00000257068.3
ENST00000528076.1
melatonin receptor 1B
chr5_+_132873660 0.31 ENST00000296877.3
liver enriched antimicrobial peptide 2
chr16_-_81220370 0.30 ENST00000337114.8
polycystin 1 like 2 (gene/pseudogene)
chr19_+_15728024 0.29 ENST00000305899.5
olfactory receptor family 10 subfamily H member 2
chr17_-_41034871 0.29 ENST00000344363.7
keratin associated protein 1-3
chr12_-_91153149 0.28 ENST00000550758.1
decorin
chr11_-_101129706 0.28 ENST00000534013.5
progesterone receptor
chr1_+_175067831 0.28 ENST00000239462.9
tenascin N
chr19_-_3557563 0.28 ENST00000389395.7
ENST00000355415.7
major facilitator superfamily domain containing 12
chr1_+_152908538 0.27 ENST00000368764.4
involucrin
chr8_-_56113982 0.27 ENST00000311923.1
MOS proto-oncogene, serine/threonine kinase
chr21_+_30396030 0.27 ENST00000355459.4
keratin associated protein 13-1
chr15_+_62561361 0.27 ENST00000561311.5
talin 2
chr18_+_61333424 0.27 ENST00000262717.9
cadherin 20
chr10_-_73591330 0.26 ENST00000451492.5
ENST00000681793.1
ENST00000680396.1
ENST00000413442.5
ubiquitin specific peptidase 54
chr6_-_25042003 0.26 ENST00000510784.8
RHO family interacting cell polarization regulator 2
chr2_+_168901290 0.26 ENST00000429379.2
ENST00000375363.8
ENST00000421979.1
glucose-6-phosphatase catalytic subunit 2
chr4_-_73620391 0.24 ENST00000395777.6
ENST00000307439.10
Ras association domain family member 6
chr11_-_35360050 0.24 ENST00000644868.1
ENST00000643454.1
ENST00000646080.1
solute carrier family 1 member 2
chr1_-_150765735 0.24 ENST00000679898.1
ENST00000448301.7
ENST00000680664.1
ENST00000679512.1
ENST00000368985.8
ENST00000679582.1
cathepsin S
chr19_+_12938598 0.23 ENST00000586760.2
ENST00000316448.10
ENST00000588454.6
calreticulin
chr7_-_81770122 0.23 ENST00000423064.7
hepatocyte growth factor
chr6_-_22297028 0.23 ENST00000306482.2
prolactin
chr4_+_70334963 0.22 ENST00000273936.6
calcium binding protein, spermatid associated 1
chr5_+_172641241 0.22 ENST00000369800.6
ENST00000520919.5
ENST00000522853.5
neuralized E3 ubiquitin protein ligase 1B
chr14_+_21990357 0.22 ENST00000390444.1
T cell receptor alpha variable 16
chr14_+_67819761 0.22 ENST00000487861.5
RAD51 paralog B
chr1_-_152414256 0.22 ENST00000271835.3
cornulin
chr11_+_5383812 0.21 ENST00000642046.1
olfactory receptor family 51 subfamily M member 1
chr19_-_45584810 0.21 ENST00000323060.3
outer mitochondrial membrane lipid metabolism regulator OPA3
chr8_+_49911801 0.21 ENST00000643809.1
syntrophin gamma 1
chr12_+_18261511 0.20 ENST00000538779.6
ENST00000433979.6
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr7_+_142399860 0.20 ENST00000390364.3
T cell receptor beta variable 10-1
chr2_-_208146150 0.20 ENST00000260988.5
crystallin gamma B
chr1_-_92486916 0.20 ENST00000294702.6
growth factor independent 1 transcriptional repressor
chr5_+_141387698 0.20 ENST00000615384.1
ENST00000519479.2
protocadherin gamma subfamily B, 4
chr18_-_36129305 0.20 ENST00000269187.10
ENST00000590986.5
ENST00000440549.6
solute carrier family 39 member 6
chr7_+_44606563 0.20 ENST00000439616.6
oxoglutarate dehydrogenase
chr18_-_36122110 0.19 ENST00000586829.1
solute carrier family 39 member 6
chr3_-_33645433 0.19 ENST00000635664.1
ENST00000485378.6
ENST00000313350.10
ENST00000487200.5
cytoplasmic linker associated protein 2
chr8_-_85341705 0.19 ENST00000517618.5
carbonic anhydrase 1
chr19_-_14835252 0.19 ENST00000641666.1
ENST00000642030.1
ENST00000642000.1
olfactory receptor family 7 subfamily C member 1
chr16_+_57976435 0.19 ENST00000290871.10
ENST00000441824.4
testis, prostate and placenta expressed
chr3_+_114294020 0.19 ENST00000383671.8
T cell immunoreceptor with Ig and ITIM domains
chr4_+_94974984 0.19 ENST00000672698.1
bone morphogenetic protein receptor type 1B
chr1_+_160190567 0.19 ENST00000368078.8
calsequestrin 1
chr19_+_15082211 0.18 ENST00000641398.1
olfactory receptor family 1 subfamily I member 1
chr19_+_37371152 0.18 ENST00000483919.5
ENST00000588911.5
ENST00000587349.1
zinc finger protein 527
chr5_-_143400716 0.18 ENST00000424646.6
ENST00000652686.1
nuclear receptor subfamily 3 group C member 1
chr21_-_42395943 0.18 ENST00000398405.5
transmembrane serine protease 3
chr7_-_88795732 0.18 ENST00000297203.3
testis expressed 47
chr11_-_101129806 0.18 ENST00000325455.10
ENST00000617858.4
ENST00000619228.2
progesterone receptor
chr3_-_151316795 0.18 ENST00000260843.5
G protein-coupled receptor 87
chr16_-_29923237 0.18 ENST00000568995.1
ENST00000566413.1
potassium channel tetramerization domain containing 13
chr10_+_24208774 0.18 ENST00000376456.8
ENST00000458595.5
ENST00000376452.7
ENST00000430453.6
KIAA1217
chr1_-_150765785 0.18 ENST00000680311.1
ENST00000681728.1
ENST00000680288.1
cathepsin S
chr17_-_48722510 0.18 ENST00000290294.5
PRAC1 small nuclear protein
chr2_+_124025280 0.18 ENST00000431078.1
ENST00000682447.1
contactin associated protein family member 5
chr11_-_36598221 0.17 ENST00000311485.8
ENST00000527033.5
ENST00000532616.1
ENST00000618712.4
recombination activating 2
chr18_+_616672 0.17 ENST00000338387.11
clusterin like 1
chr1_+_159204860 0.17 ENST00000368122.4
ENST00000368121.6
atypical chemokine receptor 1 (Duffy blood group)
chr16_+_7303245 0.17 ENST00000674626.1
RNA binding fox-1 homolog 1
chr6_-_32941018 0.17 ENST00000418107.3
major histocompatibility complex, class II, DM beta
chr8_+_109086585 0.17 ENST00000518632.2
thyrotropin releasing hormone receptor
chr6_+_131250375 0.17 ENST00000474850.2
A-kinase anchoring protein 7
chrX_+_37990773 0.17 ENST00000341016.5
H2A.P histone
chr2_-_165203870 0.17 ENST00000639244.1
ENST00000409101.7
ENST00000668657.1
sodium voltage-gated channel alpha subunit 3
chr14_+_21997531 0.17 ENST00000390445.2
T cell receptor alpha variable 17
chr5_+_90640718 0.16 ENST00000640403.1
adhesion G protein-coupled receptor V1
chr6_+_29306626 0.16 ENST00000377160.4
olfactory receptor family 14 subfamily J member 1
chr6_-_46325641 0.16 ENST00000330430.10
ENST00000405162.2
regulator of calcineurin 2
chr17_+_81683963 0.16 ENST00000676462.1
ENST00000679336.1
ENST00000678196.1
ENST00000677243.1
ENST00000677044.1
ENST00000677109.1
ENST00000677484.1
ENST00000678105.1
ENST00000677209.1
ENST00000329138.9
ENST00000677225.1
ENST00000678866.1
ENST00000676729.1
ENST00000572392.2
ENST00000577012.1
hepatocyte growth factor-regulated tyrosine kinase substrate
chr6_-_33289189 0.16 ENST00000374617.9
WD repeat domain 46
chrX_-_70260199 0.16 ENST00000374519.4
pyrimidinergic receptor P2Y4
chr7_+_148590760 0.16 ENST00000307003.3
chromosome 7 open reading frame 33
chr5_+_98773651 0.16 ENST00000513185.3
repulsive guidance molecule BMP co-receptor b
chr10_+_17951825 0.16 ENST00000539911.5
solute carrier family 39 member 12
chr10_+_17951885 0.15 ENST00000377374.8
solute carrier family 39 member 12
chr7_-_101217569 0.15 ENST00000223127.8
procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
chr8_-_40897814 0.15 ENST00000297737.11
ENST00000315769.11
zinc finger matrin-type 4
chr10_+_17951906 0.15 ENST00000377371.3
ENST00000377369.7
solute carrier family 39 member 12
chrX_+_38352573 0.15 ENST00000039007.5
ornithine transcarbamylase
chr6_+_63521738 0.15 ENST00000648894.1
ENST00000639568.2
protein tyrosine phosphatase 4A1
chr14_+_32329341 0.15 ENST00000557354.5
ENST00000557102.1
ENST00000557272.1
A-kinase anchoring protein 6
chr3_-_131026726 0.15 ENST00000514044.5
ENST00000264992.8
asteroid homolog 1
chr6_+_127577168 0.15 ENST00000329722.8
chromosome 6 open reading frame 58
chr7_+_70596078 0.15 ENST00000644506.1
activator of transcription and developmental regulator AUTS2
chr4_+_168497066 0.15 ENST00000261509.10
palladin, cytoskeletal associated protein
chr12_-_23584600 0.15 ENST00000396007.6
SRY-box transcription factor 5
chr7_-_122699108 0.14 ENST00000340112.3
ring finger protein 133
chr6_+_26365215 0.14 ENST00000527422.5
ENST00000356386.6
ENST00000396948.5
butyrophilin subfamily 3 member A2
chr11_+_5389377 0.14 ENST00000328611.5
olfactory receptor family 51 subfamily M member 1
chr15_+_58987652 0.14 ENST00000348370.9
ENST00000559160.1
ring finger protein 111
chr4_+_2418932 0.14 ENST00000635017.1
cilia and flagella associated protein 99
chr12_-_101210232 0.14 ENST00000536262.3
solute carrier family 5 member 8
chr19_-_51019699 0.14 ENST00000358789.8
kallikrein related peptidase 10
chr12_+_6904733 0.14 ENST00000007969.12
ENST00000622489.4
ENST00000443597.7
ENST00000323702.9
leucine rich repeat containing 23
chr17_-_40994159 0.14 ENST00000391586.3
keratin associated protein 3-3
chr11_-_117876612 0.14 ENST00000584230.1
ENST00000526014.6
ENST00000584394.5
ENST00000614497.5
ENST00000532984.1
FXYD domain containing ion transport regulator 6
FXYD6-FXYD2 readthrough
chr4_-_142305826 0.14 ENST00000514525.1
inositol polyphosphate-4-phosphatase type II B
chr1_+_154429315 0.14 ENST00000476006.5
interleukin 6 receptor
chr2_-_74392025 0.14 ENST00000440727.1
ENST00000409240.5
dynactin subunit 1
chr20_-_51802509 0.14 ENST00000371539.7
ENST00000217086.9
spalt like transcription factor 4
chr12_-_52618559 0.14 ENST00000305748.7
keratin 73
chr5_+_31193739 0.14 ENST00000514738.5
cadherin 6
chr19_+_18831951 0.14 ENST00000262803.10
ENST00000599848.5
UPF1 RNA helicase and ATPase
chr17_+_4807119 0.13 ENST00000263088.11
ENST00000572940.5
phospholipase D2
chr6_+_26402237 0.13 ENST00000476549.6
ENST00000450085.6
ENST00000425234.6
ENST00000427334.5
ENST00000506698.1
ENST00000289361.11
butyrophilin subfamily 3 member A1
chr14_+_100019375 0.13 ENST00000544450.6
Enah/Vasp-like
chr7_-_100119840 0.13 ENST00000437822.6
TATA-box binding protein associated factor 6
chr5_-_20575850 0.13 ENST00000507958.5
cadherin 18
chr4_-_68245683 0.13 ENST00000332644.6
transmembrane serine protease 11B
chr4_-_115113614 0.13 ENST00000264363.7
N-deacetylase and N-sulfotransferase 4
chr12_+_26195313 0.13 ENST00000422622.3
sarcospan
chr7_-_44189428 0.13 ENST00000673284.1
ENST00000403799.8
ENST00000671824.1
glucokinase
chr2_+_90209873 0.13 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr8_+_32721823 0.13 ENST00000539990.3
ENST00000519240.5
neuregulin 1
chr2_+_90100235 0.13 ENST00000492446.1
immunoglobulin kappa variable 1D-16
chrX_+_30235894 0.13 ENST00000620842.1
MAGE family member B3
chr5_-_24644968 0.13 ENST00000264463.8
cadherin 10
chr4_+_168497044 0.13 ENST00000505667.6
palladin, cytoskeletal associated protein
chr2_-_89100352 0.13 ENST00000479981.1
immunoglobulin kappa variable 1-16
chr4_-_115113822 0.13 ENST00000613194.4
N-deacetylase and N-sulfotransferase 4
chr19_-_14979848 0.13 ENST00000594383.2
solute carrier family 1 member 6
chr11_+_67452392 0.13 ENST00000438189.6
calcium binding protein 4
chr15_-_55270280 0.12 ENST00000564609.5
RAB27A, member RAS oncogene family
chr18_+_23992773 0.12 ENST00000304621.10
tetratricopeptide repeat domain 39C
chr21_+_42403874 0.12 ENST00000319294.11
ENST00000398367.1
ubiquitin associated and SH3 domain containing A
chrX_-_15314543 0.12 ENST00000344384.8
ankyrin repeat and SOCS box containing 11
chr22_-_30326923 0.12 ENST00000215790.12
TBC1 domain family member 10A
chr12_-_10826358 0.12 ENST00000240619.2
taste 2 receptor member 10
chr4_+_99511008 0.12 ENST00000514652.5
ENST00000326581.9
chromosome 4 open reading frame 17
chr9_-_21207143 0.12 ENST00000357374.2
interferon alpha 10
chr8_+_38974212 0.12 ENST00000302495.5
HtrA serine peptidase 4
chrM_+_12329 0.12 ENST00000361567.2
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5
chr16_-_29899245 0.12 ENST00000537485.5
seizure related 6 homolog like 2
chr1_-_88891496 0.12 ENST00000448623.5
ENST00000370500.10
ENST00000418217.1
general transcription factor IIB
chr13_+_45464901 0.12 ENST00000349995.10
component of oligomeric golgi complex 3
chr11_-_117929380 0.12 ENST00000528626.5
ENST00000445164.6
ENST00000430170.6
ENST00000524993.6
ENST00000526090.1
transmembrane serine protease 13
chr16_+_24729692 0.12 ENST00000315183.11
trinucleotide repeat containing adaptor 6A
chr13_-_37598750 0.12 ENST00000379743.8
ENST00000379742.4
ENST00000379749.8
ENST00000379747.9
ENST00000541179.5
ENST00000541481.5
periostin
chr8_+_104339796 0.12 ENST00000622554.1
ENST00000297581.2
dendrocyte expressed seven transmembrane protein
chr11_-_96343170 0.12 ENST00000524717.6
mastermind like transcriptional coactivator 2
chr20_+_33079640 0.12 ENST00000375483.4
BPI fold containing family B member 4
chr5_-_142698004 0.12 ENST00000407758.5
ENST00000441680.6
ENST00000419524.6
ENST00000621536.4
fibroblast growth factor 1
chr12_+_130953898 0.12 ENST00000261654.10
adhesion G protein-coupled receptor D1
chr4_+_105710809 0.11 ENST00000360505.9
ENST00000510865.5
ENST00000509336.5
glutathione S-transferase C-terminal domain containing
chr2_-_74507664 0.11 ENST00000233630.11
polycomb group ring finger 1
chr20_-_290717 0.11 ENST00000360321.7
ENST00000400269.4
chromosome 20 open reading frame 96
chr22_-_32255344 0.11 ENST00000266086.6
solute carrier family 5 member 4
chr3_+_178419123 0.11 ENST00000614557.1
ENST00000455307.5
ENST00000436432.1
potassium large conductance calcium-activated channel, subfamily M, beta member 2 (KCNMB2-IT1 - KCNMB2 readthrough transcript)
long intergenic non-protein coding RNA 1014
chr6_+_26365176 0.11 ENST00000377708.7
butyrophilin subfamily 3 member A2
chr2_+_27275429 0.11 ENST00000420191.5
ENST00000296097.8
DnaJ heat shock protein family (Hsp40) member C5 gamma
chr13_-_36214584 0.11 ENST00000317764.6
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr11_-_105035113 0.11 ENST00000526568.5
ENST00000531166.5
ENST00000534497.5
ENST00000527979.5
ENST00000533400.6
ENST00000528974.1
ENST00000525825.5
ENST00000353247.9
ENST00000446369.5
ENST00000436863.7
caspase 1
chr10_-_28282086 0.11 ENST00000375719.7
ENST00000375732.5
membrane palmitoylated protein 7
chr3_+_148730100 0.11 ENST00000474935.5
ENST00000475347.5
ENST00000461609.1
angiotensin II receptor type 1
chr17_+_32021005 0.11 ENST00000327564.11
ENST00000584368.5
ENST00000394713.7
ENST00000341671.11
leucine rich repeat containing 37B
chr11_+_5449323 0.11 ENST00000641930.1
olfactory receptor family 51 subfamily I member 2
chr6_+_42155399 0.11 ENST00000623004.2
ENST00000372963.4
ENST00000654459.1
GUCA1A neighbor
guanylate cyclase activator 1A
chr2_-_24328113 0.11 ENST00000622089.4
intersectin 2
chr6_-_31139063 0.11 ENST00000259845.5
psoriasis susceptibility 1 candidate 2
chr18_+_24460630 0.11 ENST00000256906.5
histamine receptor H4
chr14_+_69879408 0.11 ENST00000361956.8
ENST00000381280.4
SPARC related modular calcium binding 1
chr1_-_44843240 0.11 ENST00000372192.4
patched 2
chr11_-_57381146 0.11 ENST00000287143.2
proteoglycan 3, pro eosinophil major basic protein 2
chr3_-_193378747 0.10 ENST00000342358.9
ATPase 13A5

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.2 0.5 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 0.4 GO:0034769 basement membrane disassembly(GO:0034769)
0.1 0.4 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.5 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.1 0.3 GO:1901994 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.5 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 0.3 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.1 0.2 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.2 GO:0097272 ammonia homeostasis(GO:0097272)
0.1 0.3 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.1 0.6 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.3 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.1 0.9 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.2 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.0 0.1 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.3 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.2 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.2 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.3 GO:0061709 reticulophagy(GO:0061709)
0.0 0.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.1 GO:0032761 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.0 0.1 GO:0002125 maternal aggressive behavior(GO:0002125)
0.0 0.1 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.1 GO:1990523 bone regeneration(GO:1990523)
0.0 0.1 GO:0034238 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.0 0.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.2 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.1 GO:2000798 amniotic stem cell differentiation(GO:0097086) negative regulation of dense core granule biogenesis(GO:2000706) negative regulation of mesenchymal stem cell differentiation(GO:2000740) regulation of amniotic stem cell differentiation(GO:2000797) negative regulation of amniotic stem cell differentiation(GO:2000798)
0.0 0.4 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.0 0.3 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 1.1 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.2 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.1 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.3 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 0.1 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.0 0.1 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.1 GO:1900222 regulation of cell growth by extracellular stimulus(GO:0001560) negative regulation of beta-amyloid clearance(GO:1900222) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.2 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174) telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.1 GO:1901355 response to rapamycin(GO:1901355)
0.0 0.1 GO:0036135 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0 0.1 GO:0089712 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0003162 atrioventricular node development(GO:0003162)
0.0 0.3 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.1 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.2 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.5 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582) positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.0 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.0 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.0 0.0 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.0 0.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.0 1.2 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.4 GO:0043586 tongue development(GO:0043586)
0.0 0.0 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.2 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.2 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 1.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.9 GO:0016013 syntrophin complex(GO:0016013)
0.1 0.4 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.2 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.2 GO:0097179 protease inhibitor complex(GO:0097179)
0.0 0.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.3 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.6 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.0 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.3 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 1.0 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.6 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 1.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.3 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.2 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.0 0.3 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.0 0.2 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.1 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.1 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.1 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.0 0.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.6 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0052854 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 1.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.0 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 0.0 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.3 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.0 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.0 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 1.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.4 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.8 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation