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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for EN2_GBX2_LBX2

Z-value: 0.37

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Transcription factors associated with EN2_GBX2_LBX2

Gene Symbol Gene ID Gene Info
ENSG00000164778.4 EN2
ENSG00000168505.7 GBX2
ENSG00000179528.16 LBX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EN2hg38_v1_chr7_+_155458129_1554581290.154.8e-01Click!
GBX2hg38_v1_chr2_-_236168376_236168395-0.029.1e-01Click!

Activity profile of EN2_GBX2_LBX2 motif

Sorted Z-values of EN2_GBX2_LBX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of EN2_GBX2_LBX2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr18_-_74291924 1.11 ENST00000494131.6
ENST00000340533.9
ENST00000397914.4
cytochrome b5 type A
chr15_-_55270280 0.66 ENST00000564609.5
RAB27A, member RAS oncogene family
chr5_+_126423176 0.63 ENST00000542322.5
ENST00000544396.5
GRAM domain containing 2B
chr5_+_126423122 0.63 ENST00000515200.5
GRAM domain containing 2B
chr15_-_55270874 0.62 ENST00000567380.5
ENST00000565972.5
ENST00000569493.5
RAB27A, member RAS oncogene family
chr5_+_126423363 0.62 ENST00000285689.8
GRAM domain containing 2B
chr5_-_95961830 0.59 ENST00000513343.1
ENST00000237853.9
elongation factor for RNA polymerase II 2
chr15_-_55270383 0.59 ENST00000396307.6
RAB27A, member RAS oncogene family
chr2_+_149330506 0.49 ENST00000334166.9
LY6/PLAUR domain containing 6
chr17_-_40782544 0.47 ENST00000301656.4
keratin 27
chr18_+_61333424 0.46 ENST00000262717.9
cadherin 20
chr18_-_36129305 0.42 ENST00000269187.10
ENST00000590986.5
ENST00000440549.6
solute carrier family 39 member 6
chr18_+_58221535 0.39 ENST00000431212.6
ENST00000586268.5
ENST00000587190.5
NEDD4 like E3 ubiquitin protein ligase
chr5_+_141484997 0.39 ENST00000617094.1
ENST00000306593.2
ENST00000610539.1
ENST00000618371.4
protocadherin gamma subfamily C, 4
chr10_-_13707536 0.38 ENST00000632570.1
ENST00000477221.2
FERM domain containing 4A
chr20_+_18507520 0.34 ENST00000336714.8
ENST00000646240.1
ENST00000450074.6
ENST00000262544.6
SEC23 homolog B, COPII coat complex component
chr13_+_108629605 0.31 ENST00000457511.7
myosin XVI
chr5_-_35938572 0.31 ENST00000651391.1
ENST00000397366.5
ENST00000513623.5
ENST00000514524.2
ENST00000397367.6
calcyphosine like
chr7_-_122699108 0.30 ENST00000340112.3
ring finger protein 133
chr12_+_26195313 0.30 ENST00000422622.3
sarcospan
chr3_+_111998739 0.29 ENST00000393917.6
ENST00000273368.8
transgelin 3
chr18_+_34593312 0.28 ENST00000591816.6
ENST00000588125.5
ENST00000684610.1
ENST00000683705.1
ENST00000598334.5
ENST00000588684.5
ENST00000554864.7
ENST00000399121.9
ENST00000595022.5
dystrobrevin alpha
chr3_+_111999189 0.28 ENST00000455401.6
transgelin 3
chr2_-_207167220 0.27 ENST00000421199.5
ENST00000457962.5
Kruppel like factor 7
chr14_+_32329256 0.27 ENST00000280979.9
A-kinase anchoring protein 6
chr13_-_36214521 0.26 ENST00000379881.8
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr3_+_111998915 0.26 ENST00000478951.6
transgelin 3
chr3_+_130850585 0.26 ENST00000505330.5
ENST00000504381.5
ENST00000507488.6
ATPase secretory pathway Ca2+ transporting 1
chr12_-_14938508 0.25 ENST00000266397.7
endoplasmic reticulum protein 27
chr19_+_44891206 0.25 ENST00000405636.6
ENST00000252487.9
ENST00000592434.5
ENST00000589649.1
ENST00000426677.7
translocase of outer mitochondrial membrane 40
chr3_+_111999326 0.25 ENST00000494932.1
transgelin 3
chr14_-_50561119 0.24 ENST00000555216.5
mitogen-activated protein kinase kinase kinase kinase 5
chr4_-_39977836 0.23 ENST00000303538.13
ENST00000503396.5
PDS5 cohesin associated factor A
chr17_-_40755328 0.23 ENST00000312150.5
keratin 25
chr1_+_100538131 0.23 ENST00000315033.5
G protein-coupled receptor 88
chr4_+_168092530 0.23 ENST00000359299.8
annexin A10
chr4_-_145180496 0.22 ENST00000447906.8
OTU deubiquitinase 4
chr6_+_131250375 0.21 ENST00000474850.2
A-kinase anchoring protein 7
chr12_-_56300299 0.21 ENST00000552688.5
ENST00000548041.5
ENST00000551137.5
ENST00000551968.5
ENST00000351328.8
ENST00000542324.6
ENST00000546930.5
ENST00000549221.5
ENST00000550159.5
ENST00000550734.5
citrate synthase
chr11_-_117876719 0.21 ENST00000529335.6
ENST00000260282.8
FXYD domain containing ion transport regulator 6
chr12_-_56300358 0.20 ENST00000550655.5
ENST00000548567.5
ENST00000551430.6
citrate synthase
chr11_-_117876892 0.20 ENST00000539526.5
FXYD domain containing ion transport regulator 6
chr18_+_34593392 0.19 ENST00000684377.1
dystrobrevin alpha
chr10_+_24208774 0.19 ENST00000376456.8
ENST00000458595.5
ENST00000376452.7
ENST00000430453.6
KIAA1217
chr10_-_73591330 0.19 ENST00000451492.5
ENST00000681793.1
ENST00000680396.1
ENST00000413442.5
ubiquitin specific peptidase 54
chr2_+_158968608 0.19 ENST00000263635.8
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr11_-_117877463 0.19 ENST00000527717.5
FXYD domain containing ion transport regulator 6
chr19_-_6737565 0.19 ENST00000601716.1
ENST00000264080.11
G protein-coupled receptor 108
chrM_+_12329 0.18 ENST00000361567.2
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5
chr18_-_36122110 0.18 ENST00000586829.1
solute carrier family 39 member 6
chr11_+_57667747 0.18 ENST00000527985.5
zinc finger DHHC-type palmitoyltransferase 5
chr11_+_75815180 0.17 ENST00000356136.8
UV radiation resistance associated
chr12_+_53954870 0.17 ENST00000243103.4
homeobox C12
chr12_+_26195543 0.17 ENST00000242729.7
sarcospan
chr19_-_6737234 0.17 ENST00000430424.8
ENST00000597298.5
G protein-coupled receptor 108
chr6_+_106360668 0.16 ENST00000633556.3
crystallin beta-gamma domain containing 1
chr12_-_89352395 0.16 ENST00000308385.6
dual specificity phosphatase 6
chr6_-_31139063 0.15 ENST00000259845.5
psoriasis susceptibility 1 candidate 2
chr1_-_117929557 0.15 ENST00000369442.3
ENST00000369443.10
ganglioside induced differentiation associated protein 2
chr4_+_94995919 0.14 ENST00000509540.6
bone morphogenetic protein receptor type 1B
chr11_-_55936400 0.14 ENST00000301532.3
olfactory receptor family 5 subfamily I member 1
chr17_-_41055211 0.14 ENST00000542910.1
ENST00000398477.1
keratin associated protein 2-2
chr6_-_26199272 0.13 ENST00000650491.1
ENST00000635200.1
ENST00000341023.2
novel protein
H2A clustered histone 7
chr12_+_80716906 0.13 ENST00000228644.4
myogenic factor 5
chr5_+_67004618 0.13 ENST00000261569.11
ENST00000436277.5
microtubule associated serine/threonine kinase family member 4
chr8_+_91249307 0.13 ENST00000309536.6
ENST00000276609.8
solute carrier family 26 member 7
chr16_-_29899245 0.12 ENST00000537485.5
seizure related 6 homolog like 2
chr6_+_26199509 0.12 ENST00000356530.5
H2B clustered histone 7
chr3_-_195811889 0.12 ENST00000475231.5
mucin 4, cell surface associated
chr7_+_99828010 0.12 ENST00000631161.2
ENST00000354829.7
ENST00000342499.8
ENST00000417625.5
ENST00000415413.5
ENST00000444905.5
ENST00000222382.5
ENST00000312017.9
cytochrome P450 family 3 subfamily A member 43
chr14_-_81533800 0.12 ENST00000555824.5
ENST00000557372.1
ENST00000336735.9
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase
chr6_-_62286161 0.12 ENST00000281156.5
KH RNA binding domain containing, signal transduction associated 2
chr8_+_49911604 0.12 ENST00000642164.1
ENST00000644093.1
ENST00000643999.1
ENST00000647073.1
ENST00000646880.1
syntrophin gamma 1
chr17_-_41047267 0.12 ENST00000542137.1
ENST00000391419.3
keratin associated protein 2-1
chr8_+_22567038 0.12 ENST00000523348.1
sorbin and SH3 domain containing 3
chr11_+_124183219 0.12 ENST00000641351.2
olfactory receptor family 10 subfamily D member 3
chr2_+_64989343 0.12 ENST00000234256.4
solute carrier family 1 member 4
chr3_+_115623502 0.11 ENST00000305124.11
ENST00000393780.3
growth associated protein 43
chr12_-_89352487 0.11 ENST00000548755.1
ENST00000279488.8
dual specificity phosphatase 6
chr1_+_40247926 0.11 ENST00000372766.4
transmembrane and coiled-coil domains 2
chr6_-_100464912 0.11 ENST00000369208.8
SIM bHLH transcription factor 1
chr6_-_36547400 0.11 ENST00000229812.8
serine/threonine kinase 38
chr1_-_17439657 0.11 ENST00000375436.9
regulator of chromosome condensation 2
chr19_-_7633713 0.10 ENST00000311069.6
Purkinje cell protein 2
chr11_-_36598221 0.10 ENST00000311485.8
ENST00000527033.5
ENST00000532616.1
ENST00000618712.4
recombination activating 2
chr3_-_195811857 0.10 ENST00000349607.8
ENST00000346145.8
mucin 4, cell surface associated
chr8_-_86743626 0.10 ENST00000320005.6
cyclic nucleotide gated channel subunit beta 3
chr13_-_36214584 0.10 ENST00000317764.6
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr11_+_57667974 0.10 ENST00000528177.5
ENST00000287169.8
zinc finger DHHC-type palmitoyltransferase 5
chr19_+_15082211 0.10 ENST00000641398.1
olfactory receptor family 1 subfamily I member 1
chr14_+_99481395 0.10 ENST00000389879.9
ENST00000557441.5
ENST00000555049.5
ENST00000555842.1
cyclin K
chr1_+_160190567 0.10 ENST00000368078.8
calsequestrin 1
chr3_-_195811916 0.10 ENST00000463781.8
mucin 4, cell surface associated
chr19_-_3557563 0.09 ENST00000389395.7
ENST00000355415.7
major facilitator superfamily domain containing 12
chr8_+_49911396 0.09 ENST00000642720.2
syntrophin gamma 1
chr1_+_160400543 0.09 ENST00000368061.3
VANGL planar cell polarity protein 2
chr15_+_89088417 0.09 ENST00000569550.5
ENST00000565066.5
ENST00000565973.5
ENST00000352732.10
abhydrolase domain containing 2, acylglycerol lipase
chr1_-_152414256 0.09 ENST00000271835.3
cornulin
chrX_+_96684712 0.08 ENST00000373049.8
diaphanous related formin 2
chr7_-_137343752 0.08 ENST00000393083.2
pleiotrophin
chr21_-_30881572 0.08 ENST00000332378.6
keratin associated protein 11-1
chr4_-_88284553 0.08 ENST00000608933.6
ENST00000295908.11
protein phosphatase, Mg2+/Mn2+ dependent 1K
chr1_-_23344314 0.08 ENST00000374612.5
ENST00000675048.1
ENST00000478691.5
heterogeneous nuclear ribonucleoprotein R
chr10_-_49762276 0.08 ENST00000374103.9
oxoglutarate dehydrogenase L
chr19_-_41364119 0.08 ENST00000243578.8
B9 domain containing 2
chr10_+_133237849 0.08 ENST00000325980.10
VENT homeobox
chr4_-_115113614 0.08 ENST00000264363.7
N-deacetylase and N-sulfotransferase 4
chr2_+_157257687 0.08 ENST00000259056.5
polypeptide N-acetylgalactosaminyltransferase 5
chr22_+_39520553 0.07 ENST00000674920.3
ENST00000679776.1
ENST00000675582.2
ENST00000337304.2
ENST00000676346.2
ENST00000396680.3
ENST00000680446.1
ENST00000674568.2
ENST00000680748.1
ENST00000674835.2
activating transcription factor 4
chr3_-_157503574 0.07 ENST00000494677.5
ENST00000468233.5
ventricular zone expressed PH domain containing 1
chr17_-_41149823 0.07 ENST00000343246.6
keratin associated protein 4-5
chr8_-_12755457 0.07 ENST00000398246.8
LON peptidase N-terminal domain and ring finger 1
chr1_-_23344259 0.07 ENST00000476451.2
ENST00000302271.11
ENST00000606561.5
ENST00000374616.7
heterogeneous nuclear ribonucleoprotein R
chr12_-_16606795 0.07 ENST00000447609.5
LIM domain only 3
chr12_+_26195647 0.07 ENST00000535504.1
sarcospan
chr20_-_52105644 0.07 ENST00000371523.8
ZFP64 zinc finger protein
chr11_-_72112750 0.07 ENST00000545680.5
ENST00000543587.5
ENST00000538393.5
ENST00000535234.5
ENST00000227618.8
ENST00000535503.5
anaphase promoting complex subunit 15
chr4_+_7043315 0.07 ENST00000310074.8
ENST00000512388.1
transcriptional adaptor 2B
chr3_+_153162196 0.07 ENST00000323534.5
RAP2B, member of RAS oncogene family
chr20_+_33079640 0.07 ENST00000375483.4
BPI fold containing family B member 4
chr4_-_115113822 0.07 ENST00000613194.4
N-deacetylase and N-sulfotransferase 4
chr14_-_99480784 0.06 ENST00000329331.7
ENST00000436070.6
SET domain containing 3, actin histidine methyltransferase
chr11_-_72112669 0.06 ENST00000545944.5
ENST00000502597.2
anaphase promoting complex subunit 15
chrX_+_96684638 0.06 ENST00000355827.8
ENST00000373061.7
diaphanous related formin 2
chr2_-_162152404 0.06 ENST00000375497.3
glucagon
chr20_+_43667105 0.06 ENST00000217026.5
MYB proto-oncogene like 2
chr10_-_49762335 0.06 ENST00000419399.4
ENST00000432695.2
oxoglutarate dehydrogenase L
chr2_+_30146993 0.06 ENST00000261353.9
ENST00000402003.7
yippee like 5
chr2_-_77522347 0.06 ENST00000409093.1
ENST00000409884.6
ENST00000409088.3
leucine rich repeat transmembrane neuronal 4
chr8_-_33567118 0.06 ENST00000256257.2
ring finger protein 122
chr2_+_30146941 0.06 ENST00000379520.7
ENST00000379519.7
yippee like 5
chr9_+_12693327 0.06 ENST00000388918.10
tyrosinase related protein 1
chr9_+_1050330 0.05 ENST00000382255.7
ENST00000382251.7
ENST00000412350.6
ENST00000358146.7
doublesex and mab-3 related transcription factor 2
chr3_-_142029108 0.05 ENST00000497579.5
transcription factor Dp-2
chr11_-_72112068 0.05 ENST00000537644.5
ENST00000538919.5
ENST00000539395.1
ENST00000542531.5
anaphase promoting complex subunit 15
chr6_+_39792298 0.05 ENST00000633794.1
ENST00000274867.9
dishevelled associated activator of morphogenesis 2
chr7_-_73624492 0.05 ENST00000414749.6
ENST00000429400.6
ENST00000434326.5
ENST00000313375.8
ENST00000354613.5
ENST00000453275.1
MLX interacting protein like
chr1_+_203494114 0.05 ENST00000367222.7
opticin
chr22_-_33572227 0.05 ENST00000674780.1
LARGE xylosyl- and glucuronyltransferase 1
chr7_-_100119840 0.05 ENST00000437822.6
TATA-box binding protein associated factor 6
chr12_+_53268289 0.05 ENST00000257934.9
extra spindle pole bodies like 1, separase
chr3_+_172750715 0.05 ENST00000392692.8
ENST00000417960.5
ENST00000428567.5
ENST00000366090.6
ENST00000426894.5
epithelial cell transforming 2
chr4_-_88284590 0.05 ENST00000510548.6
protein phosphatase, Mg2+/Mn2+ dependent 1K
chr4_-_88284616 0.05 ENST00000508256.5
protein phosphatase, Mg2+/Mn2+ dependent 1K
chr6_-_161274010 0.05 ENST00000366911.9
ENST00000366905.3
1-acylglycerol-3-phosphate O-acyltransferase 4
chr13_-_41019289 0.05 ENST00000239882.7
E74 like ETS transcription factor 1
chr12_-_56934403 0.05 ENST00000293502.2
short chain dehydrogenase/reductase family 9C member 7
chr3_+_172750682 0.05 ENST00000232458.9
ENST00000540509.5
epithelial cell transforming 2
chr3_+_35680994 0.05 ENST00000441454.5
cAMP regulated phosphoprotein 21
chr6_-_161274042 0.04 ENST00000320285.9
1-acylglycerol-3-phosphate O-acyltransferase 4
chr3_+_173398438 0.04 ENST00000457714.5
neuroligin 1
chr19_+_7030578 0.04 ENST00000329753.5
methyl-CpG binding domain protein 3 like 5
chr17_-_10114546 0.04 ENST00000323816.8
growth arrest specific 7
chr1_+_110339462 0.04 ENST00000617047.1
RNA binding motif protein 15
chr20_-_51802433 0.04 ENST00000395997.3
spalt like transcription factor 4
chr17_-_48968587 0.04 ENST00000357424.2
gastric inhibitory polypeptide
chr12_+_6904733 0.04 ENST00000007969.12
ENST00000622489.4
ENST00000443597.7
ENST00000323702.9
leucine rich repeat containing 23
chr7_+_138460238 0.04 ENST00000343526.9
tripartite motif containing 24
chr7_+_130344837 0.04 ENST00000485477.5
ENST00000431780.6
carboxypeptidase A5
chr12_-_101210232 0.04 ENST00000536262.3
solute carrier family 5 member 8
chr2_+_170178136 0.04 ENST00000409044.7
ENST00000408978.9
myosin IIIB
chr4_+_1289870 0.04 ENST00000505177.6
ENST00000503653.5
ENST00000264750.10
ENST00000303400.9
ENST00000502558.5
ENST00000514708.5
macrophage erythroblast attacher, E3 ubiquitin ligase
chrX_+_136648138 0.04 ENST00000370629.7
CD40 ligand
chr16_+_69311339 0.03 ENST00000254950.13
vacuolar protein sorting 4 homolog A
chr14_-_99480831 0.03 ENST00000331768.10
ENST00000630307.2
SET domain containing 3, actin histidine methyltransferase
chr1_+_110339323 0.03 ENST00000602849.1
ENST00000487146.8
ENST00000618772.4
ENST00000369784.9
ENST00000650953.2
ENST00000652342.2
ENST00000654015.1
RNA binding motif protein 15
chr7_+_130344810 0.03 ENST00000497503.5
ENST00000463587.5
ENST00000461828.5
ENST00000474905.6
ENST00000494311.1
ENST00000466363.6
carboxypeptidase A5
chr1_+_179954740 0.03 ENST00000491495.2
ENST00000367607.8
centrosomal protein 350
chr3_+_4680617 0.03 ENST00000648212.1
inositol 1,4,5-trisphosphate receptor type 1
chr10_-_97687191 0.03 ENST00000370626.4
arginine vasopressin induced 1
chr4_+_70592295 0.03 ENST00000449493.2
ameloblastin
chr1_-_152159227 0.03 ENST00000316073.3
repetin
chr4_+_168497066 0.03 ENST00000261509.10
palladin, cytoskeletal associated protein
chr4_-_142305826 0.03 ENST00000514525.1
inositol polyphosphate-4-phosphatase type II B
chr17_-_66229380 0.03 ENST00000205948.11
apolipoprotein H
chrX_+_96684801 0.03 ENST00000324765.13
diaphanous related formin 2
chr10_+_84194621 0.03 ENST00000332904.7
cadherin related family member 1
chr8_+_24440930 0.03 ENST00000441335.6
ENST00000175238.10
ENST00000380789.5
ADAM metallopeptidase domain 7
chr8_-_25424260 0.03 ENST00000421054.7
gonadotropin releasing hormone 1
chr19_-_7021431 0.03 ENST00000636986.2
ENST00000637800.1
methyl-CpG binding domain protein 3 like 2B
chr1_+_117929720 0.03 ENST00000369441.7
ENST00000349139.6
WD repeat domain 3
chr17_-_41034871 0.03 ENST00000344363.7
keratin associated protein 1-3
chr11_-_13496018 0.03 ENST00000529816.1
parathyroid hormone
chr10_-_29736956 0.02 ENST00000674475.1
supervillin
chr8_-_42377227 0.02 ENST00000220812.3
dickkopf WNT signaling pathway inhibitor 4
chr4_+_143433491 0.02 ENST00000512843.1
GRB2 associated binding protein 1
chr19_-_19192122 0.02 ENST00000444486.7
ENST00000514819.7
ENST00000585679.1
ENST00000462790.8
myocyte enhancer factor 2B
BORCS8-MEF2B readthrough
BLOC-1 related complex subunit 8
chr19_-_7632971 0.02 ENST00000598935.5
Purkinje cell protein 2
chr16_+_7303245 0.02 ENST00000674626.1
RNA binding fox-1 homolog 1
chr12_+_6904962 0.02 ENST00000415834.5
ENST00000436789.5
leucine rich repeat containing 23
chr17_-_50707855 0.02 ENST00000285243.7
ankyrin repeat domain 40
chr18_+_13611910 0.02 ENST00000590308.1
low density lipoprotein receptor class A domain containing 4
chr3_-_180679468 0.02 ENST00000651046.1
ENST00000476379.6
coiled-coil domain containing 39
chr9_+_107306459 0.02 ENST00000457811.1
RAD23 homolog B, nucleotide excision repair protein
chr5_+_146447304 0.02 ENST00000296702.9
ENST00000394421.7
ENST00000679501.2
transcription elongation regulator 1
chr9_+_78297143 0.02 ENST00000347159.6
phosphoserine aminotransferase 1
chr10_-_54801179 0.01 ENST00000373955.5
protocadherin related 15
chr11_-_13495984 0.01 ENST00000282091.6
parathyroid hormone
chr14_-_36582593 0.01 ENST00000258829.6
NK2 homeobox 8
chr7_+_55365317 0.01 ENST00000254770.3
LanC like 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.3 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 1.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.2 GO:0061743 motor learning(GO:0061743)
0.0 0.3 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.6 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0061346 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.0 0.1 GO:1904397 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.0 0.2 GO:1902261 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.2 GO:0097680 maintenance of Golgi location(GO:0051684) double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.1 GO:1902731 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.1 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.7 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0061055 myotome development(GO:0061055)
0.0 0.5 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.0 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.1 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.0 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.0 0.1 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.7 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.0 GO:0034657 GID complex(GO:0034657)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 1.9 GO:0031489 myosin V binding(GO:0031489)
0.1 0.3 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.1 0.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 1.1 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.2 GO:0015266 protein channel activity(GO:0015266)
0.0 0.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.0 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 1.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis