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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for EP300

Z-value: 0.97

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Transcription factors associated with EP300

Gene Symbol Gene ID Gene Info
ENSG00000100393.14 EP300

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EP300hg38_v1_chr22_+_41092585_41092633,
hg38_v1_chr22_+_41092869_41093005
0.232.6e-01Click!

Activity profile of EP300 motif

Sorted Z-values of EP300 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of EP300

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr21_+_44697427 4.57 ENST00000618832.1
keratin associated protein 10-12
chr1_-_94541746 4.09 ENST00000334047.12
coagulation factor III, tissue factor
chr1_-_94541636 3.45 ENST00000370207.4
coagulation factor III, tissue factor
chr3_-_64445396 2.14 ENST00000295902.11
prickle planar cell polarity protein 2
chr10_-_125161019 1.78 ENST00000411419.6
C-terminal binding protein 2
chr1_+_220879434 1.77 ENST00000366903.8
H2.0 like homeobox
chr5_+_139648914 1.65 ENST00000502336.5
ENST00000520967.1
ENST00000511048.1
CXXC finger protein 5
chr11_+_65111845 1.63 ENST00000526809.5
ENST00000524986.5
ENST00000534371.5
ENST00000279263.14
ENST00000525385.5
ENST00000345348.9
ENST00000531321.5
ENST00000529414.5
ENST00000526085.5
ENST00000530750.5
transmembrane 7 superfamily member 2
chr9_+_112750722 1.62 ENST00000374232.8
sorting nexin family member 30
chr11_+_102317492 1.58 ENST00000673846.1
baculoviral IAP repeat containing 3
chr10_-_79445617 1.45 ENST00000372336.4
zinc finger CCHC-type containing 24
chr10_-_124093582 1.44 ENST00000462406.1
ENST00000435907.6
carbohydrate sulfotransferase 15
chr19_+_45340774 1.36 ENST00000589837.5
kinesin light chain 3
chrX_+_54920796 1.36 ENST00000442098.5
ENST00000430420.5
ENST00000453081.5
ENST00000319167.12
ENST00000622017.4
ENST00000375022.8
ENST00000399736.5
ENST00000440072.5
ENST00000173898.12
ENST00000431115.5
ENST00000440759.5
ENST00000375041.6
trophinin
chr21_+_44697172 1.32 ENST00000400365.3
keratin associated protein 10-12
chr1_+_109113963 1.21 ENST00000526264.5
endosome-lysosome associated apoptosis and autophagy regulator 1
chr5_-_132490750 1.17 ENST00000437654.6
ENST00000245414.9
ENST00000680139.1
ENST00000680352.1
ENST00000679440.1
ENST00000680903.1
interferon regulatory factor 1
chr19_-_38426162 1.17 ENST00000587738.2
ENST00000586305.5
RAS guanyl releasing protein 4
chr5_+_56815534 1.11 ENST00000399503.4
mitogen-activated protein kinase kinase kinase 1
chr12_-_31591129 1.09 ENST00000389082.10
DENN domain containing 5B
chr3_+_134795248 1.06 ENST00000398015.8
EPH receptor B1
chr2_+_46297397 1.03 ENST00000263734.5
endothelial PAS domain protein 1
chr14_+_56118404 1.01 ENST00000267460.9
pellino E3 ubiquitin protein ligase family member 2
chr14_-_22815801 1.00 ENST00000397532.9
solute carrier family 7 member 7
chr11_+_102317450 0.98 ENST00000615299.4
ENST00000527309.2
ENST00000526421.6
ENST00000263464.9
baculoviral IAP repeat containing 3
chr8_+_143734133 0.95 ENST00000527139.7
ENST00000533004.5
IQ motif and ankyrin repeat containing 1
chr9_+_124257923 0.91 ENST00000320246.10
ENST00000373600.7
NIMA related kinase 6
chr6_-_10414985 0.91 ENST00000466073.5
ENST00000498450.3
transcription factor AP-2 alpha
chr19_-_38426195 0.91 ENST00000615439.5
ENST00000614135.4
ENST00000622174.4
ENST00000587753.5
ENST00000454404.6
ENST00000617966.4
ENST00000618320.4
ENST00000293062.13
ENST00000433821.6
ENST00000426920.6
RAS guanyl releasing protein 4
chr11_+_102317542 0.89 ENST00000532808.5
baculoviral IAP repeat containing 3
chr14_-_22815421 0.89 ENST00000674313.1
ENST00000555959.1
solute carrier family 7 member 7
chr22_-_28741783 0.88 ENST00000439200.5
ENST00000405598.5
ENST00000398017.3
ENST00000649563.1
ENST00000650281.1
ENST00000425190.7
ENST00000404276.6
ENST00000650233.1
ENST00000348295.7
ENST00000382580.6
checkpoint kinase 2
chr4_-_148442342 0.86 ENST00000358102.8
nuclear receptor subfamily 3 group C member 2
chr1_+_109113910 0.86 ENST00000531664.5
ENST00000534476.5
endosome-lysosome associated apoptosis and autophagy regulator 1
chr4_-_148442508 0.84 ENST00000625323.2
nuclear receptor subfamily 3 group C member 2
chr18_+_9334757 0.84 ENST00000262120.10
ENST00000581641.1
twisted gastrulation BMP signaling modulator 1
chr1_-_21937300 0.76 ENST00000374695.8
heparan sulfate proteoglycan 2
chr19_+_32405758 0.76 ENST00000392250.7
dpy-19 like C-mannosyltransferase 3
chr14_-_106349792 0.75 ENST00000438142.3
immunoglobulin heavy variable 4-31
chr1_-_32702736 0.74 ENST00000373484.4
ENST00000409190.8
syncoilin, intermediate filament protein
chr17_+_59331633 0.74 ENST00000312655.9
yippee like 2
chr19_+_32405789 0.73 ENST00000586987.5
dpy-19 like C-mannosyltransferase 3
chr8_-_23164020 0.72 ENST00000312584.4
TNF receptor superfamily member 10d
chr9_-_69672341 0.71 ENST00000265381.7
amyloid beta precursor protein binding family A member 1
chrX_+_55452119 0.71 ENST00000342972.3
MAGE family member H1
chr20_-_35147285 0.70 ENST00000374491.3
ENST00000374492.8
ER degradation enhancing alpha-mannosidase like protein 2
chr10_+_74824919 0.69 ENST00000648828.1
ENST00000648725.1
lysine acetyltransferase 6B
chr10_+_74825445 0.68 ENST00000649006.1
ENST00000649463.1
ENST00000372725.6
lysine acetyltransferase 6B
chr5_-_39424966 0.68 ENST00000515700.5
ENST00000320816.11
ENST00000339788.10
DAB adaptor protein 2
chr5_+_95731300 0.68 ENST00000379982.8
Rho related BTB domain containing 3
chr5_-_39425187 0.68 ENST00000545653.5
DAB adaptor protein 2
chr2_-_27263034 0.67 ENST00000233535.9
solute carrier family 30 member 3
chr1_+_84078043 0.67 ENST00000370689.6
ENST00000370688.7
protein kinase cAMP-activated catalytic subunit beta
chrX_+_136147465 0.66 ENST00000651929.2
four and a half LIM domains 1
chr13_-_113864062 0.65 ENST00000327773.7
growth arrest specific 6
chr19_+_49114324 0.63 ENST00000391864.7
lin-7 homolog B, crumbs cell polarity complex component
chr22_-_29388530 0.61 ENST00000357586.7
ENST00000432560.6
ENST00000405198.6
ENST00000317368.11
adaptor related protein complex 1 subunit beta 1
chr1_+_153678680 0.59 ENST00000368680.4
natriuretic peptide receptor 1
chr20_+_21125999 0.58 ENST00000620891.4
kizuna centrosomal protein
chr1_+_32539418 0.58 ENST00000373510.9
ENST00000316459.4
zinc finger and BTB domain containing 8A
chr2_-_109613835 0.58 ENST00000415095.5
ENST00000437928.5
ENST00000493445.5
ENST00000397714.6
ENST00000461295.1
ENST00000397712.7
septin 10
chr2_+_190649062 0.57 ENST00000409581.5
ENST00000337386.10
NGFI-A binding protein 1
chr16_-_89720861 0.56 ENST00000389386.8
VPS9 domain containing 1
chr4_-_113761441 0.56 ENST00000394524.7
calcium/calmodulin dependent protein kinase II delta
chr8_-_98294195 0.56 ENST00000430223.7
NIPA like domain containing 2
chr3_+_134795277 0.56 ENST00000647596.1
EPH receptor B1
chr17_-_73092657 0.53 ENST00000580557.5
ENST00000579732.5
ENST00000578620.1
ENST00000542342.6
ENST00000255559.7
ENST00000579018.5
solute carrier family 39 member 11
chr22_-_28679865 0.53 ENST00000397906.6
tetratricopeptide repeat domain 28
chr2_-_98608452 0.53 ENST00000328709.8
ENST00000409997.1
cytochrome c oxidase assembly factor 5
chr3_-_169663704 0.52 ENST00000651503.2
ENST00000494292.6
ENST00000486748.2
MDS1 and EVI1 complex locus
chr14_+_66508127 0.51 ENST00000459628.5
ENST00000478722.6
gephyrin
chr3_-_72446623 0.51 ENST00000477973.4
RING1 and YY1 binding protein
chr3_+_182793478 0.51 ENST00000493826.1
ENST00000323116.10
ATPase phospholipid transporting 11B (putative)
chr20_+_44475867 0.51 ENST00000262605.9
ENST00000372904.7
ENST00000372906.2
ENST00000456317.1
alpha tocopherol transfer protein like
chr17_-_76103690 0.50 ENST00000411744.6
ENST00000634349.1
ENST00000332065.9
ENST00000607838.5
exocyst complex component 7
chr20_+_36573458 0.50 ENST00000373874.6
TGFB induced factor homeobox 2
chr20_+_21126037 0.50 ENST00000611685.4
ENST00000616848.4
kizuna centrosomal protein
chr6_+_30884063 0.49 ENST00000511510.5
ENST00000376569.7
ENST00000376570.8
ENST00000504927.5
discoidin domain receptor tyrosine kinase 1
chr17_-_76103714 0.49 ENST00000406660.4
ENST00000335146.11
ENST00000405575.8
ENST00000589210.6
exocyst complex component 7
chr8_-_98294339 0.49 ENST00000341166.3
NIPA like domain containing 2
chr18_-_36828771 0.48 ENST00000589049.5
ENST00000587129.5
ENST00000590842.5
tubulin polyglutamylase complex subunit 2
chr20_+_21126074 0.47 ENST00000619189.5
kizuna centrosomal protein
chr10_-_103452384 0.47 ENST00000369788.7
calcium homeostasis modulator family member 2
chr4_-_98143416 0.47 ENST00000295268.4
sperm tail PG-rich repeat containing 2
chr17_-_78128778 0.47 ENST00000589553.5
transmembrane channel like 6
chr8_-_7430348 0.47 ENST00000318124.3
defensin beta 103B
chr10_-_103452356 0.47 ENST00000260743.10
calcium homeostasis modulator family member 2
chr19_-_3061403 0.47 ENST00000586839.1
TLE family member 5, transcriptional modulator
chr8_+_11808417 0.46 ENST00000525954.5
farnesyl-diphosphate farnesyltransferase 1
chr1_-_68050615 0.46 ENST00000646789.1
DIRAS family GTPase 3
chr13_+_79481468 0.45 ENST00000620924.1
Nedd4 family interacting protein 2
chr15_-_42548763 0.45 ENST00000563454.5
ENST00000397130.8
ENST00000570160.1
ENST00000323443.6
leucine rich repeat containing 57
chr5_+_36151989 0.45 ENST00000274254.9
S-phase kinase associated protein 2
chr17_+_68515399 0.45 ENST00000588188.6
protein kinase cAMP-dependent type I regulatory subunit alpha
chr6_+_26087417 0.45 ENST00000357618.10
ENST00000309234.10
homeostatic iron regulator
chr7_-_37448845 0.44 ENST00000310758.9
engulfment and cell motility 1
chr9_+_79571767 0.44 ENST00000376544.7
TLE family member 4, transcriptional corepressor
chr4_-_113761068 0.44 ENST00000342666.9
ENST00000514328.5
ENST00000515496.5
ENST00000508738.5
ENST00000379773.6
calcium/calmodulin dependent protein kinase II delta
chr5_+_36152077 0.44 ENST00000546211.6
ENST00000620197.5
ENST00000678270.1
ENST00000679015.1
ENST00000678580.1
ENST00000274255.11
ENST00000508514.5
S-phase kinase associated protein 2
chr11_-_114400417 0.43 ENST00000325636.8
ENST00000623205.2
chromosome 11 open reading frame 71
chr13_+_79481446 0.43 ENST00000487865.5
Nedd4 family interacting protein 2
chr20_+_36573589 0.43 ENST00000373872.9
ENST00000650844.1
TGFB induced factor homeobox 2
chr10_+_48684859 0.43 ENST00000360890.6
ENST00000325239.11
WDFY family member 4
chr19_+_11436044 0.42 ENST00000589838.5
protein kinase C substrate 80K-H
chr8_+_23102913 0.42 ENST00000356864.4
TNF receptor superfamily member 10c
chr2_-_25673511 0.42 ENST00000407186.5
ENST00000404103.7
ENST00000405222.5
ENST00000406818.7
ENST00000407038.7
ENST00000407661.7
ENST00000288642.12
dystrobrevin beta
chr2_+_24123454 0.42 ENST00000615575.5
family with sequence similarity 228 member B
chr14_+_105472930 0.42 ENST00000483017.7
cysteine rich protein 2
chr1_+_156815633 0.42 ENST00000392302.7
ENST00000674537.1
neurotrophic receptor tyrosine kinase 1
chr12_-_105236074 0.42 ENST00000551662.5
ENST00000553097.5
ENST00000258530.8
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2
chr16_+_47461290 0.41 ENST00000566044.5
phosphorylase kinase regulatory subunit beta
chr17_+_74431338 0.41 ENST00000342648.9
ENST00000652232.1
ENST00000481232.2
G protein-coupled receptor class C group 5 member C
chr3_+_111859796 0.41 ENST00000393925.7
pleckstrin homology like domain family B member 2
chr2_-_109614143 0.40 ENST00000356688.8
septin 10
chr20_-_57711536 0.40 ENST00000265626.8
prostate transmembrane protein, androgen induced 1
chr6_+_2999961 0.40 ENST00000338130.7
N-ribosyldihydronicotinamide:quinone reductase 2
chr6_+_2988606 0.40 ENST00000380472.7
ENST00000605901.1
ENST00000454015.1
N-ribosyldihydronicotinamide:quinone reductase 2
long intergenic non-protein coding RNA 1011
chr6_+_2999885 0.40 ENST00000397717.7
ENST00000380455.11
N-ribosyldihydronicotinamide:quinone reductase 2
chr9_+_79571956 0.40 ENST00000376552.8
TLE family member 4, transcriptional corepressor
chr20_+_21125981 0.40 ENST00000619574.4
kizuna centrosomal protein
chr7_+_65873324 0.40 ENST00000434382.2
vitamin K epoxide reductase complex subunit 1 like 1
chr2_+_169694434 0.39 ENST00000616481.4
ENST00000616524.4
ENST00000617738.4
ENST00000359744.8
ENST00000438838.5
ENST00000438710.5
ENST00000449906.5
ENST00000498202.6
ENST00000272797.8
phosphatase, orphan 2
kelch like family member 23
chr1_+_153728042 0.39 ENST00000318967.7
ENST00000435409.6
integrator complex subunit 3
chr6_+_2999984 0.39 ENST00000380441.5
ENST00000380454.8
N-ribosyldihydronicotinamide:quinone reductase 2
chr1_-_54053192 0.39 ENST00000371337.3
ENST00000234831.10
transmembrane protein 59
chr16_-_47461259 0.39 ENST00000544001.6
integrin alpha FG-GAP repeat containing 1
chr1_+_175000126 0.38 ENST00000406752.1
ENST00000405362.1
calcyclin binding protein
chr8_+_11809135 0.38 ENST00000528643.5
ENST00000525777.5
farnesyl-diphosphate farnesyltransferase 1
chr8_-_27772585 0.38 ENST00000522915.5
ENST00000356537.9
coiled-coil domain containing 25
chr6_+_30884353 0.38 ENST00000428153.6
ENST00000376568.8
ENST00000452441.5
ENST00000515219.5
discoidin domain receptor tyrosine kinase 1
chr1_+_1615478 0.38 ENST00000355826.10
ENST00000505820.7
ENST00000518681.6
ENST00000520777.6
MIB E3 ubiquitin protein ligase 2
chr8_+_94719865 0.37 ENST00000414645.6
dpy-19 like 4
chr19_-_1174227 0.37 ENST00000587024.5
ENST00000361757.8
strawberry notch homolog 2
chr19_-_10194898 0.36 ENST00000359526.9
ENST00000679103.1
ENST00000676610.1
ENST00000678804.1
ENST00000679313.1
ENST00000677946.1
DNA methyltransferase 1
chr19_-_49808639 0.36 ENST00000529634.2
fuzzy planar cell polarity protein
chr9_+_128456135 0.36 ENST00000604420.5
ENST00000448249.7
ENST00000393527.7
outer dense fiber of sperm tails 2
chr5_-_112419251 0.36 ENST00000261486.6
erythrocyte membrane protein band 4.1 like 4A
chr11_-_130314858 0.35 ENST00000527478.6
ENST00000357899.9
zinc finger and BTB domain containing 44
chr17_-_81295267 0.35 ENST00000288439.9
ENST00000374759.8
solute carrier family 38 member 10
chr6_+_24494939 0.34 ENST00000348925.2
ENST00000357578.8
aldehyde dehydrogenase 5 family member A1
chr3_-_130746760 0.34 ENST00000356763.8
phosphoinositide-3-kinase regulatory subunit 4
chr15_+_90352239 0.33 ENST00000354377.8
ENST00000379090.9
zinc finger protein 774
chr1_+_12063285 0.33 ENST00000263932.7
TNF receptor superfamily member 8
chr1_-_11805977 0.33 ENST00000376486.3
methylenetetrahydrofolate reductase
chr19_-_45768627 0.33 ENST00000560160.1
SIX homeobox 5
chr9_+_128456418 0.32 ENST00000434106.7
ENST00000546203.5
ENST00000446274.5
ENST00000421776.6
ENST00000432065.6
outer dense fiber of sperm tails 2
chr15_-_89690775 0.32 ENST00000559170.1
peroxisomal biogenesis factor 11 alpha
chr13_+_79481124 0.32 ENST00000612570.4
ENST00000218652.11
Nedd4 family interacting protein 2
chr5_+_43603163 0.31 ENST00000660752.1
ENST00000654405.1
ENST00000344920.9
ENST00000657172.1
ENST00000512996.6
ENST00000671668.1
nicotinamide nucleotide transhydrogenase
chr1_+_12063357 0.31 ENST00000417814.3
TNF receptor superfamily member 8
chr1_-_16437190 0.30 ENST00000540400.1
spermatogenesis associated 21
chr21_-_37072997 0.30 ENST00000430792.1
ENST00000399103.5
phosphatidylinositol glycan anchor biosynthesis class P
chr16_-_27268579 0.30 ENST00000564342.5
ENST00000567710.5
ENST00000563273.5
ENST00000361439.9
NSE1 homolog, SMC5-SMC6 complex component
chr17_+_39688079 0.30 ENST00000578199.5
erb-b2 receptor tyrosine kinase 2
chr8_+_10672646 0.29 ENST00000521818.1
chromosome 8 open reading frame 74
chr11_-_118252279 0.29 ENST00000525386.5
ENST00000527472.1
ENST00000278949.9
myelin protein zero like 3
chr2_-_69643615 0.29 ENST00000409068.5
AP2 associated kinase 1
chr15_-_52179881 0.29 ENST00000396335.8
ENST00000560116.1
ENST00000358784.11
G protein subunit beta 5
chr9_-_19049319 0.29 ENST00000542071.2
ENST00000649457.1
stabilizer of axonemal microtubules 1
chr22_+_37560472 0.29 ENST00000430687.1
ENST00000249014.5
CDC42 effector protein 1
chr5_+_65926556 0.29 ENST00000380943.6
ENST00000416865.6
ENST00000380935.5
ENST00000284037.10
erbb2 interacting protein
chr11_-_107712049 0.29 ENST00000305991.3
sarcolipin
chr2_+_197804583 0.28 ENST00000428675.6
phospholipase C like 1 (inactive)
chr10_-_125160499 0.28 ENST00000494626.6
ENST00000337195.9
C-terminal binding protein 2
chr19_+_11435619 0.28 ENST00000589126.5
ENST00000588269.1
ENST00000587509.5
ENST00000591462.6
ENST00000592741.5
ENST00000677123.1
ENST00000593101.5
ENST00000587327.5
protein kinase C substrate 80K-H
chr20_-_31723902 0.28 ENST00000676942.1
ENST00000450273.2
ENST00000678563.1
ENST00000456404.6
ENST00000420488.6
ENST00000439267.2
BCL2 like 1
chr20_+_19758245 0.28 ENST00000255006.12
Ras and Rab interactor 2
chr6_+_26087281 0.28 ENST00000353147.9
ENST00000397022.7
ENST00000352392.8
ENST00000349999.8
ENST00000317896.11
ENST00000470149.5
ENST00000336625.12
ENST00000461397.5
ENST00000488199.5
homeostatic iron regulator
chr16_-_19522062 0.28 ENST00000353258.8
glycerophosphodiester phosphodiesterase 1
chr6_+_135181268 0.27 ENST00000341911.10
ENST00000442647.7
ENST00000618728.4
ENST00000316528.12
ENST00000616088.4
MYB proto-oncogene, transcription factor
chr7_+_95772506 0.27 ENST00000537881.5
ENST00000447467.6
ENST00000524053.5
ENST00000324972.10
ENST00000630942.2
ENST00000437599.5
ENST00000359388.8
ENST00000413338.5
dynein cytoplasmic 1 intermediate chain 1
chr2_+_171922442 0.27 ENST00000264108.5
histone acetyltransferase 1
chr15_-_74433942 0.27 ENST00000543145.6
ENST00000261918.9
semaphorin 7A (John Milton Hagen blood group)
chr16_+_2033264 0.27 ENST00000565855.5
ENST00000566198.1
SLC9A3 regulator 2
chr1_+_159437845 0.27 ENST00000642080.1
olfactory receptor family 10 subfamily J member 1
chr20_+_35455141 0.27 ENST00000446710.5
ENST00000420564.5
centrosomal protein 250
chr17_+_21284701 0.26 ENST00000529517.1
ENST00000627447.1
ENST00000342679.9
mitogen-activated protein kinase kinase 3
chr17_+_28662183 0.26 ENST00000347486.8
ENST00000314616.11
SPT6 homolog, histone chaperone and transcription elongation factor
chr1_-_224434750 0.26 ENST00000414423.9
ENST00000678917.1
ENST00000678555.1
ENST00000678307.1
WD repeat domain 26
chr21_-_29939912 0.26 ENST00000399907.5
ENST00000399909.5
glutamate ionotropic receptor kainate type subunit 1
chr16_-_47461039 0.26 ENST00000320640.11
integrin alpha FG-GAP repeat containing 1
chr9_+_128456006 0.26 ENST00000351030.7
ENST00000372814.7
outer dense fiber of sperm tails 2
chr2_+_73926826 0.26 ENST00000629438.2
ENST00000348222.3
ENST00000264093.9
deoxyguanosine kinase
chr2_+_32165841 0.26 ENST00000357055.7
ENST00000435660.5
ENST00000440718.5
ENST00000379343.6
ENST00000282587.9
ENST00000406369.2
solute carrier family 30 member 6
chr19_+_49114352 0.25 ENST00000221459.7
ENST00000486217.2
lin-7 homolog B, crumbs cell polarity complex component
chr11_-_8964927 0.25 ENST00000525069.5
TMEM9 domain family member B
chr18_+_7567266 0.25 ENST00000580170.6
protein tyrosine phosphatase receptor type M
chr6_-_31897675 0.25 ENST00000375530.8
ENST00000375537.8
euchromatic histone lysine methyltransferase 2
chr12_+_53300027 0.25 ENST00000549488.5
MYG1 exonuclease
chr16_+_47461314 0.25 ENST00000299167.12
ENST00000323584.10
ENST00000563376.5
phosphorylase kinase regulatory subunit beta
chr15_-_101652365 0.25 ENST00000428002.6
ENST00000333202.8
ENST00000559107.5
ENST00000347970.7
TM2 domain containing 3
chr19_-_18538371 0.25 ENST00000596015.1
FKBP prolyl isomerase 8
chr17_-_28661897 0.25 ENST00000247020.9
stromal cell derived factor 2
chr1_+_32247212 0.25 ENST00000373582.4
family with sequence similarity 167 member B
chr15_+_74541200 0.24 ENST00000622429.1
ENST00000346246.10
AT-rich interaction domain 3B
chr7_-_32070809 0.24 ENST00000396182.6
phosphodiesterase 1C
chr11_+_64340191 0.24 ENST00000356786.10
coiled-coil domain containing 88B
chr22_-_42646960 0.24 ENST00000402438.5
ENST00000407623.7
ENST00000438270.1
cytochrome b5 reductase 3
chr19_+_57231014 0.24 ENST00000302804.12
aurora kinase C
chr19_+_57231001 0.24 ENST00000415300.6
aurora kinase C

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.5 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.5 1.6 GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission(GO:0099557)
0.5 1.4 GO:0035026 leading edge cell differentiation(GO:0035026)
0.4 0.8 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.3 0.9 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.3 1.2 GO:0035740 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.3 1.9 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.3 1.9 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.3 1.8 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.2 0.7 GO:0034761 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.2 0.7 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.2 0.9 GO:0003409 optic cup structural organization(GO:0003409)
0.2 3.7 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.2 0.7 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.2 0.6 GO:0045554 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759) TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.2 2.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2 0.5 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.2 0.5 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 0.9 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.9 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.8 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.4 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.1 0.8 GO:0070827 chromatin maintenance(GO:0070827)
0.1 0.9 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.3 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.1 0.7 GO:0097338 response to clozapine(GO:0097338)
0.1 1.1 GO:0043129 surfactant homeostasis(GO:0043129)
0.1 0.3 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.4 GO:0090301 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1 0.9 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 1.0 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.1 1.1 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.6 GO:0030421 defecation(GO:0030421)
0.1 0.3 GO:0006083 acetate metabolic process(GO:0006083)
0.1 1.0 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 0.4 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 0.3 GO:0009631 cold acclimation(GO:0009631)
0.1 0.3 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 1.0 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) regulation of histone deacetylase activity(GO:1901725)
0.1 0.9 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.1 0.4 GO:0021553 olfactory nerve development(GO:0021553)
0.1 0.4 GO:0071105 response to interleukin-11(GO:0071105)
0.1 0.3 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.5 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.1 0.2 GO:0006550 isoleucine catabolic process(GO:0006550)
0.1 1.6 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.1 0.2 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.1 0.3 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 2.1 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.1 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.0 0.5 GO:0072553 terminal button organization(GO:0072553)
0.0 0.3 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.1 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0 0.2 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.0 0.6 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.6 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.2 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.4 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.6 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.9 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.4 GO:0039526 suppression by virus of host apoptotic process(GO:0019050) modulation by virus of host apoptotic process(GO:0039526)
0.0 0.1 GO:0034414 tRNA 3'-trailer cleavage, endonucleolytic(GO:0034414) tRNA 3'-trailer cleavage(GO:0042779)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.9 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.3 GO:0016557 peroxisome membrane biogenesis(GO:0016557) regulation of peroxisome size(GO:0044375)
0.0 0.2 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.3 GO:0033088 regulation of immature T cell proliferation in thymus(GO:0033084) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.3 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.2 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.1 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.0 0.3 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.5 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.0 0.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.5 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.3 GO:1904781 regulation of centriole-centriole cohesion(GO:0030997) positive regulation of protein localization to centrosome(GO:1904781)
0.0 0.3 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 5.8 GO:0031424 keratinization(GO:0031424)
0.0 0.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.0 0.3 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.3 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.3 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.2 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.5 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.0 0.2 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.1 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.2 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.4 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.2 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 1.0 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 1.4 GO:0007566 embryo implantation(GO:0007566)
0.0 0.7 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.1 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.0 0.2 GO:0046070 dGTP metabolic process(GO:0046070)
0.0 1.3 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 1.6 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.5 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 1.1 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0 0.1 GO:0033085 negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of thymocyte aggregation(GO:2000399)
0.0 0.1 GO:0071226 response to molecule of fungal origin(GO:0002238) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) cellular response to molecule of fungal origin(GO:0071226)
0.0 1.2 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.2 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 1.0 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.2 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.2 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.5 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 1.5 GO:0008088 axo-dendritic transport(GO:0008088)
0.0 0.3 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.1 GO:0060374 mast cell differentiation(GO:0060374)
0.0 0.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.1 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.5 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:0060431 primary lung bud formation(GO:0060431)
0.0 1.5 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.0 GO:0060164 noradrenergic neuron development(GO:0003358) neuroblast differentiation(GO:0014016) spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) stem cell fate determination(GO:0048867) regulation of timing of neuron differentiation(GO:0060164) olfactory pit development(GO:0060166)
0.0 0.4 GO:0016180 snRNA processing(GO:0016180)
0.0 0.5 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.8 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.2 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0030576 Cajal body organization(GO:0030576)
0.0 0.2 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.3 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.3 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 1.6 GO:0060071 Wnt signaling pathway, planar cell polarity pathway(GO:0060071)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 2.7 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.1 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 1.1 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.2 GO:0007398 ectoderm development(GO:0007398)
0.0 0.2 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.6 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.4 GO:0046329 negative regulation of JNK cascade(GO:0046329)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 7.5 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 2.1 GO:0097470 ribbon synapse(GO:0097470)
0.1 1.0 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.7 GO:1990357 terminal web(GO:1990357)
0.1 0.3 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 1.4 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.4 GO:0070876 SOSS complex(GO:0070876)
0.1 1.6 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.9 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.7 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 5.7 GO:0045095 keratin filament(GO:0045095)
0.1 0.9 GO:0001520 outer dense fiber(GO:0001520)
0.1 1.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.5 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.5 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 1.2 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 0.9 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 3.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.3 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.3 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.9 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.4 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.3 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 1.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.0 GO:0031251 PAN complex(GO:0031251)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.6 GO:0030131 clathrin adaptor complex(GO:0030131)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.4 1.6 GO:0001512 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.3 2.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.3 1.1 GO:0045569 TRAIL binding(GO:0045569)
0.2 1.4 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.2 0.5 GO:0061598 nitrate reductase activity(GO:0008940) molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 1.0 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.1 0.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.8 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 1.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.6 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.3 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.1 1.9 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.3 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.9 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.6 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 2.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 4.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.7 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.4 GO:0010465 neurotrophin p75 receptor binding(GO:0005166) nerve growth factor receptor activity(GO:0010465)
0.1 2.1 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 0.7 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 1.4 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.6 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 1.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.2 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.1 0.5 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.7 GO:0039706 co-receptor binding(GO:0039706)
0.1 1.0 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.9 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 1.2 GO:0031432 titin binding(GO:0031432)
0.0 0.2 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.9 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 7.6 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.0 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.2 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.3 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.3 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 1.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.8 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.3 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 1.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.3 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 1.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.8 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.3 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 1.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.2 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.3 GO:0017136 NAD-dependent histone deacetylase activity(GO:0017136)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 1.4 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 1.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 1.0 GO:0004402 histone acetyltransferase activity(GO:0004402)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 0.3 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.3 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 2.1 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.9 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.6 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.0 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.8 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.4 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.8 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.5 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.5 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 1.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 2.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.7 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 0.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.9 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 1.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.1 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 1.3 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.9 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.1 REACTOME KINESINS Genes involved in Kinesins
0.0 0.9 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.0 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 1.0 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.3 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.0 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 1.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.5 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 1.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.0 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.1 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)