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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for EPAS1_BCL3

Z-value: 0.96

Motif logo

Transcription factors associated with EPAS1_BCL3

Gene Symbol Gene ID Gene Info
ENSG00000116016.14 EPAS1
ENSG00000069399.15 BCL3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EPAS1hg38_v1_chr2_+_46297397_46297414-0.301.4e-01Click!
BCL3hg38_v1_chr19_+_44751251_44751321-0.184.0e-01Click!

Activity profile of EPAS1_BCL3 motif

Sorted Z-values of EPAS1_BCL3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of EPAS1_BCL3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_-_169980474 2.53 ENST00000377365.4
inhibitory synaptic factor family member 2B
chr3_-_116444983 1.42 ENST00000333617.8
limbic system associated membrane protein
chr14_+_32934383 1.35 ENST00000551634.6
neuronal PAS domain protein 3
chr16_+_57628507 1.24 ENST00000456916.5
ENST00000567154.5
ENST00000388813.9
ENST00000562558.6
ENST00000566271.6
ENST00000563374.5
ENST00000673126.2
ENST00000562631.7
ENST00000568234.5
ENST00000565770.5
ENST00000566164.5
adhesion G protein-coupled receptor G1
chr7_+_154305256 1.22 ENST00000619756.4
dipeptidyl peptidase like 6
chr17_-_43545636 0.98 ENST00000393664.6
ETS variant transcription factor 4
chr8_+_62248591 0.88 ENST00000519049.6
sodium/potassium transporting ATPase interacting 3
chr1_-_44031446 0.82 ENST00000372310.8
ENST00000466926.1
solute carrier family 6 member 9
chr1_+_40374648 0.81 ENST00000372708.5
small ArfGAP2
chr1_-_150235972 0.80 ENST00000534220.1
acidic nuclear phosphoprotein 32 family member E
chr11_-_72722302 0.75 ENST00000334211.12
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr17_-_43546323 0.71 ENST00000545954.5
ENST00000319349.10
ETS variant transcription factor 4
chr7_-_27152561 0.70 ENST00000467897.2
ENST00000612286.5
ENST00000498652.1
novel transcript
homeobox A3
novel transcript
chr17_-_43545707 0.70 ENST00000545089.5
ETS variant transcription factor 4
chr5_-_136365476 0.69 ENST00000378459.7
ENST00000502753.4
ENST00000513104.6
ENST00000352189.8
transient receptor potential cation channel subfamily C member 7
chr1_+_115641945 0.68 ENST00000355485.7
ENST00000369510.8
VANGL planar cell polarity protein 1
chr12_+_65824475 0.68 ENST00000403681.7
high mobility group AT-hook 2
chr8_-_69834970 0.66 ENST00000260126.9
solute carrier organic anion transporter family member 5A1
chr6_-_42722590 0.66 ENST00000230381.7
peripherin 2
chr22_-_37149900 0.64 ENST00000216223.10
interleukin 2 receptor subunit beta
chr1_-_44031352 0.63 ENST00000372306.7
ENST00000475075.6
solute carrier family 6 member 9
chr9_+_72628020 0.59 ENST00000646619.1
transmembrane channel like 1
chr8_+_76683779 0.57 ENST00000523885.2
zinc finger homeobox 4
chr14_+_70641896 0.53 ENST00000256367.3
tetratricopeptide repeat domain 9
chr19_+_55857437 0.53 ENST00000587891.5
NLR family pyrin domain containing 4
chr17_-_43545891 0.52 ENST00000591713.5
ENST00000538265.5
ETS variant transcription factor 4
chr3_-_58587033 0.50 ENST00000447756.2
family with sequence similarity 107 member A
chr1_+_184386978 0.50 ENST00000235307.7
chromosome 1 open reading frame 21
chr22_+_41976933 0.49 ENST00000396425.7
septin 3
chr2_-_168913277 0.48 ENST00000451987.5
SPC25 component of NDC80 kinetochore complex
chr7_-_41703062 0.48 ENST00000242208.5
inhibin subunit beta A
chr2_+_205683109 0.48 ENST00000357118.8
ENST00000272849.7
ENST00000412873.2
neuropilin 2
chr14_+_21887848 0.46 ENST00000390437.2
T cell receptor alpha variable 12-2
chr3_-_9249623 0.46 ENST00000383836.8
SLIT-ROBO Rho GTPase activating protein 3
chr19_+_41219235 0.46 ENST00000359092.7
AXL receptor tyrosine kinase
chr19_+_15049469 0.45 ENST00000427043.4
caspase 14
chr11_-_75351686 0.44 ENST00000360025.7
arrestin beta 1
chr12_-_16608183 0.43 ENST00000354662.5
ENST00000538051.5
LIM domain only 3
chr17_+_4715438 0.43 ENST00000571206.1
arrestin beta 2
chr13_-_33205997 0.42 ENST00000399365.7
StAR related lipid transfer domain containing 13
chr7_+_87628538 0.42 ENST00000394654.3
RUN domain containing 3B
chr2_+_74654228 0.42 ENST00000611975.4
ENST00000357877.7
ENST00000339773.9
ENST00000434486.5
ssemaphorin 4F
chr5_-_59356962 0.42 ENST00000405755.6
phosphodiesterase 4D
chr9_+_92974476 0.42 ENST00000337352.10
FYVE, RhoGEF and PH domain containing 3
chr3_-_127823235 0.41 ENST00000398104.5
monoglyceride lipase
chr19_+_58326991 0.41 ENST00000329665.5
zinc finger and SCAN domain containing 22
chr22_+_39456996 0.41 ENST00000341184.7
beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
chr19_-_48513161 0.41 ENST00000673139.1
lemur tyrosine kinase 3
chr2_-_100142575 0.40 ENST00000317233.8
ENST00000672204.1
ENST00000416492.5
ENST00000672857.1
ENST00000672756.2
AF4/FMR2 family member 3
chr12_-_117968972 0.40 ENST00000339824.7
kinase suppressor of ras 2
chr3_-_127823177 0.40 ENST00000434178.6
monoglyceride lipase
chr9_+_72577939 0.40 ENST00000645773.1
transmembrane channel like 1
chr3_-_127822835 0.39 ENST00000453507.6
monoglyceride lipase
chr9_+_72577788 0.39 ENST00000645208.2
transmembrane channel like 1
chr7_-_117323041 0.38 ENST00000491214.1
ENST00000265441.8
Wnt family member 2
chr3_+_14402592 0.38 ENST00000622186.5
ENST00000621751.4
solute carrier family 6 member 6
chr19_+_44942268 0.38 ENST00000591600.1
apolipoprotein C4
chr12_-_2835018 0.37 ENST00000337508.9
nuclear receptor interacting protein 2
chr5_-_59039454 0.37 ENST00000358923.10
phosphodiesterase 4D
chr12_-_16608073 0.37 ENST00000441439.6
LIM domain only 3
chr1_-_30757767 0.37 ENST00000294507.4
lysosomal protein transmembrane 5
chr19_-_35134861 0.36 ENST00000591633.2
leucine rich repeat LGI family member 4
chr13_-_101416441 0.36 ENST00000675332.1
ENST00000676315.1
ENST00000251127.11
sodium leak channel, non-selective
chr13_-_52739769 0.35 ENST00000448904.6
ENST00000377962.8
chondromodulin
chr9_+_2621766 0.35 ENST00000382100.8
very low density lipoprotein receptor
chr8_-_27479229 0.34 ENST00000407991.3
cholinergic receptor nicotinic alpha 2 subunit
chr12_+_26195647 0.34 ENST00000535504.1
sarcospan
chr5_+_52989314 0.34 ENST00000296585.10
integrin subunit alpha 2
chr22_+_41976760 0.33 ENST00000396426.7
ENST00000406029.5
septin 3
chr9_+_2622053 0.33 ENST00000681306.1
ENST00000681618.1
very low density lipoprotein receptor
chr7_+_87628355 0.33 ENST00000338056.7
ENST00000493037.5
RUN domain containing 3B
chr3_-_185152974 0.33 ENST00000335012.3
chromosome 3 open reading frame 70
chr17_-_8087709 0.33 ENST00000647874.1
arachidonate 12-lipoxygenase, 12R type
chr11_+_128891468 0.33 ENST00000338350.4
potassium inwardly rectifying channel subfamily J member 5
chr14_+_22226711 0.32 ENST00000390463.3
T cell receptor alpha variable 36/delta variable 7
chr3_-_58627596 0.32 ENST00000474531.5
ENST00000465970.1
family with sequence similarity 107 member A
chr15_+_33310946 0.32 ENST00000415757.7
ENST00000634891.2
ENST00000389232.9
ENST00000622037.1
ryanodine receptor 3
chr19_+_10452891 0.32 ENST00000344979.7
phosphodiesterase 4A
chr5_-_173328407 0.32 ENST00000265087.9
stanniocalcin 2
chr7_-_38330935 0.32 ENST00000390343.2
T cell receptor gamma variable 8
chrX_-_20116871 0.32 ENST00000379651.7
ENST00000443379.7
ENST00000379643.10
MAP7 domain containing 2
chr6_-_31652358 0.32 ENST00000456622.5
ENST00000435080.5
ENST00000375976.8
ENST00000441054.5
BAG cochaperone 6
chr8_+_62248933 0.31 ENST00000523211.5
ENST00000524201.1
sodium/potassium transporting ATPase interacting 3
chr9_+_2621556 0.31 ENST00000680746.1
very low density lipoprotein receptor
chr9_+_18474100 0.31 ENST00000327883.11
ENST00000431052.6
ENST00000380570.8
ENST00000380548.9
ADAMTS like 1
chr3_-_128493173 0.31 ENST00000498200.1
ENST00000341105.7
GATA binding protein 2
chr2_-_85418421 0.31 ENST00000409275.1
capping actin protein, gelsolin like
chr11_+_10450627 0.31 ENST00000396554.7
ENST00000524866.5
adenosine monophosphate deaminase 3
chr19_-_11197516 0.31 ENST00000592903.5
ENST00000586659.6
ENST00000589359.5
ENST00000588724.5
KN motif and ankyrin repeat domains 2
chr6_-_11807045 0.30 ENST00000379415.6
androgen dependent TFPI regulating protein
chr7_-_100167222 0.30 ENST00000411994.1
galactose-3-O-sulfotransferase 4
chr7_+_20615653 0.30 ENST00000404938.7
ATP binding cassette subfamily B member 5
chr1_-_153565535 0.30 ENST00000368707.5
S100 calcium binding protein A2
chr19_-_51387955 0.30 ENST00000221973.7
ENST00000596399.2
lens intrinsic membrane protein 2
chr14_+_79279403 0.30 ENST00000281127.11
neurexin 3
chr12_-_24562438 0.30 ENST00000646273.1
ENST00000659413.1
ENST00000446891.7
SRY-box transcription factor 5
chr3_-_158105718 0.29 ENST00000554685.2
short stature homeobox 2
chr2_+_218382265 0.29 ENST00000233202.11
solute carrier family 11 member 1
chr6_+_43770202 0.29 ENST00000372067.8
ENST00000672860.2
vascular endothelial growth factor A
chr11_-_134411854 0.29 ENST00000392580.5
beta-1,3-glucuronyltransferase 1
chr1_+_13584262 0.29 ENST00000376061.8
ENST00000513143.5
podoplanin
chr11_-_69819410 0.29 ENST00000334134.4
fibroblast growth factor 3
chr4_-_121072519 0.29 ENST00000379692.9
neuron derived neurotrophic factor
chr11_-_79441016 0.29 ENST00000278550.12
teneurin transmembrane protein 4
chr16_+_83971451 0.29 ENST00000565691.5
N-terminal EF-hand calcium binding protein 2
chr20_+_52972347 0.28 ENST00000371497.10
teashirt zinc finger homeobox 2
chr7_-_130686545 0.28 ENST00000356588.8
ENST00000443954.5
ENST00000438346.1
testis specific 13
chr8_+_109086585 0.28 ENST00000518632.2
thyrotropin releasing hormone receptor
chr15_+_48191648 0.28 ENST00000646012.1
ENST00000561127.5
ENST00000647546.1
ENST00000559641.5
ENST00000417307.3
solute carrier family 12 member 1
cortexin 2
chr17_+_21376321 0.28 ENST00000583088.6
potassium inwardly rectifying channel subfamily J member 12
chr11_+_76783349 0.28 ENST00000333090.5
tsukushi, small leucine rich proteoglycan
chr7_+_75398915 0.28 ENST00000437796.1
tripartite motif containing 73
chr17_-_31321603 0.28 ENST00000462804.3
ecotropic viral integration site 2A
chrX_+_1268786 0.27 ENST00000501036.7
ENST00000417535.7
colony stimulating factor 2 receptor subunit alpha
chr14_+_93927358 0.27 ENST00000557000.2
family with sequence similarity 181 member A
chr7_+_142332182 0.27 ENST00000547918.2
T cell receptor beta variable 7-1 (non-functional)
chr14_-_91244669 0.27 ENST00000650645.1
G protein-coupled receptor 68
chr14_-_91244508 0.27 ENST00000535815.5
ENST00000529102.1
G protein-coupled receptor 68
chr5_+_175872741 0.27 ENST00000502265.5
complexin 2
chr12_-_102481744 0.27 ENST00000644491.1
insulin like growth factor 1
chr11_-_30586866 0.27 ENST00000528686.2
metallophosphoesterase domain containing 2
chrX_+_1268807 0.27 ENST00000381524.8
ENST00000381529.9
ENST00000412290.6
colony stimulating factor 2 receptor subunit alpha
chr1_-_44017296 0.27 ENST00000357730.6
ENST00000360584.6
ENST00000528803.1
solute carrier family 6 member 9
chr22_+_21632751 0.26 ENST00000292779.4
coiled-coil domain containing 116
chr2_+_241687059 0.26 ENST00000636051.1
inhibitor of growth family member 5
chr19_+_41219177 0.26 ENST00000301178.9
AXL receptor tyrosine kinase
chr12_+_6914571 0.26 ENST00000229277.6
ENST00000538763.5
ENST00000545045.6
enolase 2
chr19_+_39704461 0.26 ENST00000360675.7
ENST00000392052.8
ENST00000601802.1
galectin 14
chr3_-_127822455 0.26 ENST00000265052.10
monoglyceride lipase
chr7_+_114414997 0.26 ENST00000462331.5
ENST00000393491.7
ENST00000403559.8
ENST00000408937.7
ENST00000393498.6
ENST00000393495.7
ENST00000378237.7
forkhead box P2
chr20_+_9069076 0.26 ENST00000378473.9
phospholipase C beta 4
chr16_-_30010972 0.26 ENST00000565273.5
ENST00000567332.6
ENST00000350119.9
double C2 domain alpha
chr19_-_43082692 0.26 ENST00000406487.6
pregnancy specific beta-1-glycoprotein 2
chr7_-_36724380 0.25 ENST00000617267.4
acyloxyacyl hydrolase
chr19_-_42917837 0.25 ENST00000292125.6
ENST00000402603.8
ENST00000594375.1
ENST00000187910.7
pregnancy specific beta-1-glycoprotein 6
chr4_+_61202142 0.25 ENST00000514591.5
adhesion G protein-coupled receptor L3
chr11_+_105610883 0.25 ENST00000531011.5
ENST00000525187.5
ENST00000530497.1
glutamate ionotropic receptor AMPA type subunit 4
chr18_+_46334197 0.25 ENST00000588679.1
ENST00000543885.2
ring finger protein 165
chr13_-_101416362 0.24 ENST00000675802.1
ENST00000675150.1
sodium leak channel, non-selective
chr6_+_34236865 0.24 ENST00000674029.1
ENST00000447654.5
ENST00000347617.10
ENST00000401473.7
ENST00000311487.9
high mobility group AT-hook 1
chrX_-_11265975 0.24 ENST00000303025.10
ENST00000657361.1
Rho GTPase activating protein 6
chr14_+_95876385 0.24 ENST00000504119.1
TCL1 upstream neural differentiation-associated RNA
chr19_+_12995467 0.24 ENST00000592199.6
nuclear factor I X
chr22_+_31092447 0.23 ENST00000455608.5
smoothelin
chr3_+_14402576 0.23 ENST00000613060.4
solute carrier family 6 member 6
chr7_+_114414809 0.23 ENST00000350908.9
forkhead box P2
chr3_-_179072205 0.23 ENST00000432729.5
zinc finger matrin-type 3
chr7_+_127593727 0.23 ENST00000478821.1
ENST00000265825.6
fascin actin-bundling protein 3
chr19_-_16471943 0.23 ENST00000602151.1
ENST00000597937.5
ENST00000455140.7
ENST00000535753.6
epidermal growth factor receptor pathway substrate 15 like 1
chr11_-_27700472 0.23 ENST00000418212.5
ENST00000533246.5
brain derived neurotrophic factor
chr5_+_80960354 0.23 ENST00000265080.9
Ras protein specific guanine nucleotide releasing factor 2
chr6_-_24358036 0.23 ENST00000378454.8
doublecortin domain containing 2
chrX_-_143635081 0.23 ENST00000338017.8
SLIT and NTRK like family member 4
chr1_+_22643626 0.23 ENST00000374640.9
ENST00000374639.7
ENST00000374637.1
complement C1q C chain
chr5_-_181205284 0.23 ENST00000334421.5
tripartite motif containing 7
chr7_-_27102669 0.23 ENST00000222718.7
homeobox A2
chr5_+_32711313 0.23 ENST00000265074.13
natriuretic peptide receptor 3
chrX_-_72305892 0.23 ENST00000450875.5
ENST00000417400.1
ENST00000431381.5
ENST00000445983.5
ENST00000651998.1
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1
chr2_-_40452046 0.22 ENST00000406785.6
solute carrier family 8 member A1
chr12_-_10884244 0.22 ENST00000543626.4
proline rich protein HaeIII subfamily 1
chr22_-_37427433 0.22 ENST00000452946.1
ENST00000402918.7
extracellular leucine rich repeat and fibronectin type III domain containing 2
extracellular leucine rich repeat and fibronectin type III domain containing 2
chr11_+_31812307 0.22 ENST00000643436.1
ENST00000646959.1
ENST00000645942.1
ENST00000530348.5
PAX6 upstream antisense RNA
novel protein
chr2_+_219572304 0.22 ENST00000243786.3
inhibin subunit alpha
chr6_+_36678699 0.22 ENST00000405375.5
ENST00000244741.10
ENST00000373711.3
cyclin dependent kinase inhibitor 1A
chr4_-_167234266 0.22 ENST00000511269.5
ENST00000506697.5
ENST00000512042.1
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr11_-_75351609 0.22 ENST00000420843.7
arrestin beta 1
chr21_-_30497160 0.22 ENST00000334058.3
keratin associated protein 19-4
chr22_-_21551461 0.22 ENST00000433039.2
RIMS binding protein 3C
chr19_-_39320839 0.22 ENST00000248668.5
leucine rich repeat and fibronectin type III domain containing 1
chr12_-_54984667 0.22 ENST00000524668.5
ENST00000533607.1
ENST00000449076.6
thymocyte expressed, positive selection associated 1
chr19_+_30372364 0.22 ENST00000355537.4
zinc finger protein 536
chr14_+_104581141 0.21 ENST00000410013.1
chromosome 14 open reading frame 180
chr11_-_8268716 0.21 ENST00000428101.6
LIM domain only 1
chr11_+_10450289 0.21 ENST00000444303.6
adenosine monophosphate deaminase 3
chr5_-_170389349 0.21 ENST00000274629.9
potassium calcium-activated channel subfamily M regulatory beta subunit 1
chr22_-_18611919 0.21 ENST00000619918.1
RIMS binding protein 3
chr11_+_34642468 0.21 ENST00000527935.1
ETS homologous factor
chr14_+_22052503 0.21 ENST00000390449.3
T cell receptor alpha variable 21
chr11_+_117986386 0.21 ENST00000227752.8
interleukin 10 receptor subunit alpha
chr10_+_92593112 0.21 ENST00000260731.5
kinesin family member 11
chr18_+_34493289 0.21 ENST00000682923.1
ENST00000596745.5
ENST00000283365.14
ENST00000315456.10
ENST00000598774.6
ENST00000684266.1
ENST00000683092.1
ENST00000683379.1
ENST00000684359.1
dystrobrevin alpha
chr4_+_85827891 0.21 ENST00000514229.5
Rho GTPase activating protein 24
chr17_+_6070361 0.21 ENST00000317744.10
WSC domain containing 1
chr17_-_58328756 0.20 ENST00000268893.10
ENST00000343736.9
TSPO associated protein 1
chr6_-_41286665 0.20 ENST00000589614.5
ENST00000244709.9
ENST00000334475.10
ENST00000591620.1
triggering receptor expressed on myeloid cells 1
chr19_+_44942230 0.20 ENST00000592954.2
ENST00000589057.5
apolipoprotein C4
APOC4-APOC2 readthrough (NMD candidate)
chr18_+_65751000 0.20 ENST00000397968.4
cadherin 7
chr4_+_85827745 0.20 ENST00000509300.5
Rho GTPase activating protein 24
chr3_+_127629161 0.20 ENST00000342480.7
podocalyxin like 2
chr22_+_31127749 0.20 ENST00000402238.5
ENST00000404453.5
ENST00000401755.1
inositol polyphosphate-5-phosphatase J
chr6_-_31592952 0.20 ENST00000376073.8
ENST00000376072.7
natural cytotoxicity triggering receptor 3
chr1_-_247758680 0.20 ENST00000408896.4
olfactory receptor family 1 subfamily C member 1
chrX_+_17375230 0.20 ENST00000380060.7
NHS actin remodeling regulator
chr17_-_31314066 0.20 ENST00000577894.1
ecotropic viral integration site 2B
chr8_-_27478851 0.20 ENST00000240132.7
cholinergic receptor nicotinic alpha 2 subunit
chr2_-_96035974 0.20 ENST00000434632.5
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr1_-_211492111 0.20 ENST00000367002.5
ENST00000680073.1
RD3 regulator of GUCY2D
chr13_-_78603539 0.20 ENST00000377208.7
POU class 4 homeobox 1
chr4_+_89111521 0.20 ENST00000603357.3
tigger transposable element derived 2
chr12_+_56021316 0.20 ENST00000547791.2
IKAROS family zinc finger 4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.2 1.1 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.2 0.7 GO:0045578 negative regulation of B cell differentiation(GO:0045578) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.2 0.5 GO:0021757 caudate nucleus development(GO:0021757) putamen development(GO:0021758)
0.2 1.5 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.6 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 1.4 GO:0060005 vestibular reflex(GO:0060005)
0.1 1.0 GO:0034436 glycoprotein transport(GO:0034436)
0.1 0.5 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816) protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 1.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 0.4 GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550)
0.1 0.8 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.1 GO:0060066 oviduct development(GO:0060066)
0.1 0.3 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.7 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.1 0.3 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.1 0.3 GO:0048058 compound eye corneal lens development(GO:0048058)
0.1 0.2 GO:0051885 positive regulation of anagen(GO:0051885)
0.1 0.6 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.3 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.3 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.2 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.1 0.8 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.4 GO:1902943 regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943)
0.1 0.3 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.1 0.8 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.3 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.1 0.2 GO:0036451 cap mRNA methylation(GO:0036451)
0.1 0.2 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.1 0.2 GO:0021593 rhombomere morphogenesis(GO:0021593) rhombomere 3 morphogenesis(GO:0021658)
0.1 0.3 GO:0036135 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.1 0.3 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.1 0.3 GO:1904021 negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.1 0.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 1.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.4 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.3 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 0.4 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.1 0.7 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.1 0.2 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 0.3 GO:0072302 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.1 0.6 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.1 0.6 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.2 GO:0042938 dipeptide transport(GO:0042938)
0.1 0.2 GO:0001507 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.1 0.5 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.2 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.1 0.5 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 0.6 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 0.2 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.2 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.3 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.1 0.2 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.1 GO:0060948 cardiac vascular smooth muscle cell development(GO:0060948)
0.1 0.2 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1 0.3 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1 0.7 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.7 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.4 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.1 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0 0.2 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.0 GO:1903970 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.4 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.0 0.7 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.3 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.4 GO:0097490 sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.0 1.2 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.4 GO:0051971 positive regulation of transmission of nerve impulse(GO:0051971)
0.0 0.4 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.5 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.2 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.8 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.3 GO:0060467 negative regulation of fertilization(GO:0060467)
0.0 0.1 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.1 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.1 GO:1904045 cellular response to aldosterone(GO:1904045)
0.0 1.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0052148 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.1 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.2 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 0.3 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.5 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.2 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.4 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.1 GO:0032827 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.0 0.1 GO:1904582 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.0 0.1 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.2 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.4 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.2 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.1 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.1 GO:0035744 T-helper 1 cell cytokine production(GO:0035744)
0.0 0.3 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.0 0.1 GO:0090133 corticotropin hormone secreting cell differentiation(GO:0060128) mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.0 0.1 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.2 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.1 GO:1990918 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.0 0.3 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.3 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.2 GO:0097283 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.0 0.2 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.0 0.1 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.2 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.4 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.0 0.2 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.2 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0051939 gamma-aminobutyric acid import(GO:0051939)
0.0 0.1 GO:1903182 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.0 0.1 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.0 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.1 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 0.0 GO:0034971 histone H3-R17 methylation(GO:0034971)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.2 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.2 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.1 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.1 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.1 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.0 0.4 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.2 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.2 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.2 GO:0003360 brainstem development(GO:0003360)
0.0 0.1 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.0 0.1 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.4 GO:0030157 pancreatic juice secretion(GO:0030157)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.0 0.3 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0043605 cellular amide catabolic process(GO:0043605)
0.0 0.1 GO:0098923 positive regulation of adrenergic receptor signaling pathway(GO:0071879) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.0 0.1 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.3 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.1 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.1 GO:0051792 short-chain fatty acid biosynthetic process(GO:0051790) medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.1 GO:1903413 cellular response to bile acid(GO:1903413)
0.0 0.0 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.0 0.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.4 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.0 GO:0002818 intracellular defense response(GO:0002818)
0.0 0.0 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.0 0.3 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.0 0.0 GO:0030035 microspike assembly(GO:0030035) actin filament uncapping(GO:0051695)
0.0 0.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.3 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.6 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.1 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.0 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.0 0.2 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.5 GO:0014733 regulation of skeletal muscle adaptation(GO:0014733)
0.0 0.2 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.1 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 0.2 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.1 GO:0072144 glomerular mesangial cell development(GO:0072144)
0.0 0.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.0 0.0 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.3 GO:0006029 proteoglycan metabolic process(GO:0006029)
0.0 0.3 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.0 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.1 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.9 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.1 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0 0.0 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.0 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.2 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.1 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.1 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.2 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.3 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.0 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.1 GO:0089711 L-glutamate transmembrane transport(GO:0089711)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 1.1 GO:0097451 glial limiting end-foot(GO:0097451)
0.1 1.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.5 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.5 GO:0072534 perineuronal net(GO:0072534)
0.1 0.6 GO:0031262 Ndc80 complex(GO:0031262)
0.1 1.4 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.3 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 0.3 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 0.2 GO:0030689 Noc complex(GO:0030689)
0.0 0.1 GO:0030312 external encapsulating structure(GO:0030312)
0.0 0.4 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.6 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.7 GO:0033643 host cell part(GO:0033643)
0.0 1.0 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 0.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 1.1 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.3 GO:0043203 axon hillock(GO:0043203)
0.0 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.0 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
0.0 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.7 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.6 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 1.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.4 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.7 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0032009 early phagosome(GO:0032009)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.2 1.0 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.2 0.7 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.2 0.4 GO:0031691 alpha-1A adrenergic receptor binding(GO:0031691) follicle-stimulating hormone receptor binding(GO:0031762)
0.2 0.8 GO:0035501 MH1 domain binding(GO:0035501)
0.2 0.5 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.2 0.2 GO:0097604 temperature-gated cation channel activity(GO:0097604)
0.2 0.6 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.1 1.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.3 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.1 0.2 GO:0070697 activin receptor binding(GO:0070697)
0.1 0.3 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 0.4 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.1 0.4 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.3 GO:0030305 heparanase activity(GO:0030305)
0.1 0.3 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 1.1 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.2 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 1.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.4 GO:0042835 BRE binding(GO:0042835)
0.1 0.3 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.1 0.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.6 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.3 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.4 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.3 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.3 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 0.5 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.3 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.1 0.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.4 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.1 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.7 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 1.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.1 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.2 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.3 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.3 GO:0098639 collagen receptor activity(GO:0038064) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.6 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.2 GO:0004074 biliverdin reductase activity(GO:0004074)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.3 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0015154 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.9 GO:0022840 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.9 GO:0048018 receptor agonist activity(GO:0048018)
0.0 1.1 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.2 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.2 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.1 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 1.0 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 0.6 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 1.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.3 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.1 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 0.0 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.1 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.3 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.2 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.3 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.2 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.3 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.1 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 1.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.0 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.2 GO:0008061 chitin binding(GO:0008061)
0.0 0.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.0 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.0 GO:0030395 lactose binding(GO:0030395)
0.0 0.0 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.0 0.0 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.0 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 2.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.0 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.7 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.4 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.0 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 2.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.7 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.2 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 1.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.1 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.1 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.0 1.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.8 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.2 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.8 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.1 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.3 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.5 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway