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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for ESRRB_ESRRG

Z-value: 0.85

Motif logo

Transcription factors associated with ESRRB_ESRRG

Gene Symbol Gene ID Gene Info
ENSG00000119715.15 ESRRB
ENSG00000196482.18 ESRRG

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ESRRGhg38_v1_chr1_-_217076889_217076997-0.213.0e-01Click!
ESRRBhg38_v1_chr14_+_76376113_76376151-0.087.2e-01Click!

Activity profile of ESRRB_ESRRG motif

Sorted Z-values of ESRRB_ESRRG motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ESRRB_ESRRG

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_-_123620496 1.85 ENST00000578202.1
myosin light chain kinase
chr3_-_123620571 1.81 ENST00000583087.5
myosin light chain kinase
chr14_-_58427134 1.30 ENST00000555930.6
translocase of inner mitochondrial membrane 9
chr20_-_63499074 1.23 ENST00000217182.6
ENST00000642899.1
eukaryotic translation elongation factor 1 alpha 2
chr15_-_90932517 1.17 ENST00000330334.7
ENST00000394272.8
ENST00000559898.5
HD domain containing 3
chr14_-_73760259 1.10 ENST00000286523.9
ENST00000435371.1
mitotic deacetylase associated SANT domain protein
chr2_-_105438503 0.98 ENST00000393352.7
ENST00000607522.1
four and a half LIM domains 2
chr1_-_23177683 0.94 ENST00000302291.8
leucine zipper protein 1
chr6_+_107028188 0.88 ENST00000311381.8
ENST00000405204.6
mitochondrial transcription rescue factor 1
chr13_+_32586443 0.85 ENST00000315596.15
PDS5 cohesin associated factor B
chr1_-_201023694 0.85 ENST00000332129.6
ENST00000422435.2
ENST00000461742.7
kinesin family member 21B
chr2_-_74147868 0.84 ENST00000295326.4
ENST00000327428.10
bolA family member 3
chr3_+_113948004 0.84 ENST00000638807.2
zinc finger DHHC-type palmitoyltransferase 23
chr20_-_37527723 0.82 ENST00000397135.1
ENST00000397137.5
BLCAP apoptosis inducing factor
chr3_+_113947901 0.82 ENST00000330212.7
ENST00000498275.5
zinc finger DHHC-type palmitoyltransferase 23
chr3_+_10026409 0.82 ENST00000287647.7
ENST00000676013.1
ENST00000675286.1
ENST00000419585.5
FA complementation group D2
chr14_-_58427114 0.78 ENST00000556007.6
translocase of inner mitochondrial membrane 9
chr13_+_40789548 0.77 ENST00000338625.9
solute carrier family 25 member 15
chr14_-_58427158 0.77 ENST00000555097.1
ENST00000556367.6
ENST00000555404.5
translocase of inner mitochondrial membrane 9
chr12_-_110920568 0.76 ENST00000548438.1
ENST00000228841.15
myosin light chain 2
chr7_-_138774036 0.75 ENST00000393054.5
ENST00000483139.1
ATPase H+ transporting V0 subunit a4
chr16_-_3717505 0.75 ENST00000538171.5
ENST00000246957.10
TNF receptor associated protein 1
chr11_-_34357994 0.72 ENST00000435224.3
ankyrin repeat and BTB domain containing 2
chr20_-_37527862 0.72 ENST00000373537.7
ENST00000445723.5
ENST00000414080.1
BLCAP apoptosis inducing factor
chr15_-_90932476 0.71 ENST00000561036.1
HD domain containing 3
chr14_-_106658251 0.71 ENST00000454421.2
immunoglobulin heavy variable 3-64
chr20_-_37527891 0.68 ENST00000414542.6
BLCAP apoptosis inducing factor
chr16_+_641792 0.68 ENST00000307650.9
ENST00000629534.2
MAPK regulated corepressor interacting protein 2
chr3_-_42701513 0.68 ENST00000310417.9
hedgehog acyltransferase like
chr3_-_42702778 0.66 ENST00000457462.5
ENST00000441594.6
hedgehog acyltransferase like
chr22_+_31122923 0.66 ENST00000620191.4
ENST00000412277.6
ENST00000412985.5
ENST00000331075.10
ENST00000420017.5
ENST00000400294.6
ENST00000405300.5
ENST00000404390.7
inositol polyphosphate-5-phosphatase J
chr1_-_241519701 0.65 ENST00000366560.4
ENST00000683521.1
fumarate hydratase
chr6_-_168093012 0.63 ENST00000646385.1
FERM domain containing 1
chr16_-_30526518 0.63 ENST00000380412.7
zinc finger protein 768
chr12_-_52926459 0.62 ENST00000552150.5
keratin 8
chr11_+_66857056 0.60 ENST00000309602.5
ENST00000393952.3
leucine rich repeat and fibronectin type III domain containing 4
chr18_-_21704763 0.60 ENST00000580981.5
ENST00000289119.7
abhydrolase domain containing 3, phospholipase
chr9_-_35685462 0.59 ENST00000607559.1
tropomyosin 2
chr12_+_51912329 0.57 ENST00000547400.5
ENST00000550683.5
ENST00000419526.6
activin A receptor like type 1
chr22_+_40177917 0.57 ENST00000454349.7
ENST00000335727.13
trinucleotide repeat containing adaptor 6B
chr20_+_34977625 0.57 ENST00000618182.6
myosin heavy chain 7B
chr1_-_39575686 0.57 ENST00000677006.1
ENST00000678625.1
ENST00000677609.1
poly(A) binding protein cytoplasmic 4
chr20_+_59577463 0.55 ENST00000359926.7
phosphatase and actin regulator 3
chr19_+_13906255 0.53 ENST00000589606.5
coiled-coil and C2 domain containing 1A
chr6_+_54083423 0.53 ENST00000460844.6
ENST00000370876.6
muscular LMNA interacting protein
chr8_-_134510182 0.52 ENST00000521673.5
zinc finger and AT-hook domain containing
chr2_-_42493970 0.51 ENST00000394973.4
ENST00000306078.2
potassium voltage-gated channel modifier subfamily G member 3
chr10_-_35642286 0.51 ENST00000374694.3
frizzled class receptor 8
chr18_-_26548527 0.51 ENST00000580059.7
potassium channel tetramerization domain containing 1
chr13_-_40771105 0.51 ENST00000323563.8
mitochondrial ribosomal protein S31
chr2_+_219498857 0.51 ENST00000684669.1
ENST00000373917.7
ENST00000435316.6
ENST00000313597.10
ENST00000358215.8
ENST00000373908.5
ENST00000622191.2
ENST00000683752.1
ENST00000341142.8
GDP-mannose pyrophosphorylase A
chr20_+_59604527 0.51 ENST00000371015.6
phosphatase and actin regulator 3
chr12_-_106138946 0.51 ENST00000261402.7
NUAK family kinase 1
chr22_+_20774092 0.50 ENST00000215727.10
serpin family D member 1
chr8_-_92095598 0.49 ENST00000520724.5
ENST00000518844.5
RUNX1 partner transcriptional co-repressor 1
chr12_+_6867420 0.49 ENST00000613953.4
ENST00000396705.10
triosephosphate isomerase 1
chr3_+_155870623 0.49 ENST00000295920.7
ENST00000496455.7
guanine monophosphate synthase
chr8_-_52714414 0.46 ENST00000435644.6
ENST00000518710.5
ENST00000025008.10
ENST00000517963.1
RB1 inducible coiled-coil 1
chr13_-_110561668 0.45 ENST00000267328.5
RAB20, member RAS oncogene family
chr9_+_137255277 0.44 ENST00000343053.6
negative elongation factor complex member B
chr7_-_27185223 0.44 ENST00000517402.1
ENST00000006015.4
homeobox A11
chr1_-_241357171 0.43 ENST00000440928.6
regulator of G protein signaling 7
chr2_-_241637045 0.43 ENST00000407315.6
THAP domain containing 4
chr1_-_241357085 0.42 ENST00000366564.5
regulator of G protein signaling 7
chr16_+_31355215 0.42 ENST00000562522.2
integrin subunit alpha X
chr9_+_133061981 0.42 ENST00000372080.8
carboxyl ester lipase
chr16_+_727117 0.41 ENST00000562141.5
hydroxyacylglutathione hydrolase like
chr7_-_42152396 0.41 ENST00000642432.1
ENST00000647255.1
ENST00000677288.1
GLI family zinc finger 3
chr12_+_51424802 0.41 ENST00000453097.7
solute carrier family 4 member 8
chr1_-_241357225 0.41 ENST00000366565.5
regulator of G protein signaling 7
chr10_-_73874502 0.41 ENST00000372765.5
ENST00000351293.7
ENST00000441192.2
ENST00000423381.6
calcium/calmodulin dependent protein kinase II gamma
chr10_-_73874568 0.41 ENST00000322635.7
ENST00000322680.7
ENST00000394762.7
ENST00000680035.1
calcium/calmodulin dependent protein kinase II gamma
chr15_+_76059973 0.41 ENST00000388942.8
transmembrane protein 266
chr2_+_219627394 0.41 ENST00000373760.6
solute carrier family 4 member 3
chr9_-_128204218 0.41 ENST00000634901.1
ENST00000372948.7
CDKN1A interacting zinc finger protein 1
chr20_+_32277626 0.41 ENST00000375712.4
kinesin family member 3B
chr1_+_161202147 0.40 ENST00000392179.5
ENST00000678511.1
ENST00000677453.1
ENST00000678783.1
ENST00000679218.1
ENST00000676972.1
NADH:ubiquinone oxidoreductase core subunit S2
chr8_-_124539037 0.40 ENST00000519232.5
ENST00000523888.5
ENST00000522810.5
ENST00000519548.5
ENST00000517678.5
ENST00000605953.5
ENST00000276692.11
ENST00000630259.1
TatD DNase domain containing 1
chr20_+_13785017 0.40 ENST00000378106.10
ENST00000463598.1
NADH:ubiquinone oxidoreductase complex assembly factor 5
chr1_+_153628393 0.40 ENST00000368696.3
ENST00000292169.6
ENST00000436839.1
S100 calcium binding protein A1
chr17_-_6713359 0.39 ENST00000381074.8
ENST00000433363.7
ENST00000293800.10
ENST00000572352.5
ENST00000573648.5
solute carrier family 13 member 5
chr12_-_2004421 0.39 ENST00000280665.11
ENST00000535873.2
decapping mRNA 1B
chr6_-_119078642 0.39 ENST00000621231.4
ENST00000338891.12
family with sequence similarity 184 member A
chr14_-_103522696 0.39 ENST00000553878.5
ENST00000348956.7
ENST00000557530.1
creatine kinase B
chr2_+_197500371 0.38 ENST00000409468.1
ENST00000233893.10
heat shock protein family E (Hsp10) member 1
chr16_-_46973634 0.38 ENST00000317089.10
DnaJ heat shock protein family (Hsp40) member A2
chr2_-_175181663 0.38 ENST00000392541.3
ENST00000284727.9
ENST00000409194.5
ATP synthase membrane subunit c locus 3
chr5_+_218241 0.38 ENST00000617470.4
ENST00000504309.5
ENST00000510361.5
ENST00000264932.11
succinate dehydrogenase complex flavoprotein subunit A
chr7_-_27180230 0.37 ENST00000396344.4
homeobox A10
chr9_-_135961310 0.37 ENST00000371756.4
UBA domain containing 1
chr3_-_50567646 0.37 ENST00000426034.5
ENST00000441239.5
chromosome 3 open reading frame 18
chr2_-_43995950 0.37 ENST00000683590.1
ENST00000683623.1
ENST00000682779.1
ENST00000682546.1
ENST00000683220.1
ENST00000683125.1
ENST00000683833.1
ENST00000683989.1
ENST00000682480.1
ENST00000260665.12
ENST00000682308.1
ENST00000682885.1
ENST00000409659.6
ENST00000447246.2
leucine rich pentatricopeptide repeat containing
chr5_-_60844185 0.36 ENST00000505959.5
ELOVL fatty acid elongase 7
chr10_-_119165542 0.36 ENST00000419372.5
ENST00000369131.8
ENST00000355697.7
sideroflexin 4
chr4_-_76036060 0.36 ENST00000306621.8
C-X-C motif chemokine ligand 11
chr2_-_43995999 0.36 ENST00000683213.1
ENST00000409946.6
leucine rich pentatricopeptide repeat containing
chr5_-_96433214 0.36 ENST00000311106.8
proprotein convertase subtilisin/kexin type 1
chr3_-_14124816 0.36 ENST00000295767.9
ENST00000396914.4
coiled-coil-helix-coiled-coil-helix domain containing 4
chr8_-_109691766 0.36 ENST00000529190.5
ENST00000422135.5
syntabulin
chr2_+_219627650 0.35 ENST00000317151.7
solute carrier family 4 member 3
chr12_+_25195205 0.35 ENST00000557540.7
electron transfer flavoprotein regulatory factor 1
chr12_+_25195230 0.35 ENST00000381356.9
electron transfer flavoprotein regulatory factor 1
chr19_+_1248553 0.35 ENST00000586757.5
ENST00000300952.6
ENST00000682408.1
midnolin
chr20_-_13784880 0.35 ENST00000202816.5
ENST00000617257.2
ESF1 nucleolar pre-rRNA processing protein homolog
chr9_-_127874964 0.35 ENST00000373156.5
adenylate kinase 1
chr2_+_219627622 0.34 ENST00000358055.8
solute carrier family 4 member 3
chr14_+_22516273 0.34 ENST00000390510.1
T cell receptor alpha joining 27
chr16_+_10944547 0.34 ENST00000409790.6
ENST00000409552.4
C-type lectin domain containing 16A
chr19_+_2249317 0.34 ENST00000221496.5
anti-Mullerian hormone
chr11_-_72752376 0.34 ENST00000393609.8
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr3_-_49340013 0.34 ENST00000351842.8
ENST00000416417.5
ENST00000415188.1
ENST00000265560.9
ubiquitin specific peptidase 4
chr11_-_1762403 0.34 ENST00000367196.4
cathepsin D
chr1_+_103571077 0.33 ENST00000610648.1
amylase alpha 2B
chr2_+_227325349 0.33 ENST00000436237.5
ENST00000443428.6
ENST00000418961.5
mitochondrial fission factor
chr3_+_16265160 0.33 ENST00000627468.2
ENST00000605932.5
ENST00000435829.6
ENST00000285083.10
oxidoreductase NAD binding domain containing 1
chr3_-_49120887 0.33 ENST00000453664.5
ENST00000398888.6
ubiquitin specific peptidase 19
chr4_-_142305935 0.33 ENST00000511838.5
inositol polyphosphate-4-phosphatase type II B
chr2_-_158380960 0.32 ENST00000409187.5
coiled-coil domain containing 148
chr19_+_34365240 0.32 ENST00000586425.2
glucose-6-phosphate isomerase
chrX_+_16650155 0.32 ENST00000380200.3
S100 calcium binding protein G
chr15_-_72231113 0.32 ENST00000565154.6
ENST00000565184.6
ENST00000335181.10
pyruvate kinase M1/2
chr7_+_55964577 0.32 ENST00000446778.5
ENST00000322090.8
nipsnap homolog 2
chr20_+_3796288 0.32 ENST00000439880.6
ENST00000245960.10
cell division cycle 25B
chr15_-_41402445 0.31 ENST00000676906.1
ENST00000679094.1
ENST00000558719.2
ENST00000260361.9
ENST00000560978.2
ENST00000676533.1
NADH:ubiquinone oxidoreductase complex assembly factor 1
chr12_+_6535278 0.31 ENST00000396858.5
glyceraldehyde-3-phosphate dehydrogenase
chr13_+_108269880 0.31 ENST00000542136.1
TNF superfamily member 13b
chr18_-_5543988 0.31 ENST00000341928.7
erythrocyte membrane protein band 4.1 like 3
chr2_+_219627565 0.31 ENST00000273063.10
solute carrier family 4 member 3
chr2_-_169573856 0.31 ENST00000453153.7
ENST00000445210.1
FAST kinase domains 1
chr10_-_73874461 0.31 ENST00000305762.11
calcium/calmodulin dependent protein kinase II gamma
chr19_-_15125751 0.31 ENST00000263383.8
ilvB acetolactate synthase like
chr10_+_69318831 0.30 ENST00000359426.7
hexokinase 1
chr2_-_169573766 0.30 ENST00000438035.5
ENST00000453929.6
FAST kinase domains 1
chr16_+_28863812 0.30 ENST00000684370.1
SH2B adaptor protein 1
chr7_+_39623886 0.30 ENST00000436179.1
RAS like proto-oncogene A
chr18_-_5543960 0.30 ENST00000400111.8
erythrocyte membrane protein band 4.1 like 3
chr17_-_63842663 0.30 ENST00000613943.4
ENST00000448276.7
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr17_+_50346099 0.30 ENST00000017003.7
ENST00000509778.1
ENST00000507602.5
xylosyltransferase 2
chr15_-_72231583 0.29 ENST00000566809.1
ENST00000567087.5
ENST00000569050.1
ENST00000568883.5
pyruvate kinase M1/2
chr7_-_42152444 0.29 ENST00000479210.1
GLI family zinc finger 3
chr19_+_34365173 0.29 ENST00000589640.5
ENST00000591204.5
ENST00000589399.6
ENST00000356487.11
glucose-6-phosphate isomerase
chr3_-_49120785 0.29 ENST00000417901.5
ENST00000306026.5
ENST00000434032.6
ubiquitin specific peptidase 19
chr4_-_142846275 0.29 ENST00000513000.5
ENST00000509777.5
ENST00000503927.5
inositol polyphosphate-4-phosphatase type II B
chr3_+_16265330 0.29 ENST00000606098.1
oxidoreductase NAD binding domain containing 1
chr16_+_28863757 0.29 ENST00000618521.4
ENST00000359285.9
ENST00000538342.5
SH2B adaptor protein 1
chr17_-_2025289 0.29 ENST00000331238.7
reticulon 4 receptor like 1
chr11_+_34916611 0.29 ENST00000227868.9
ENST00000430469.6
ENST00000533262.1
pyruvate dehydrogenase complex component X
chr1_+_45913647 0.29 ENST00000674079.1
microtubule associated serine/threonine kinase 2
chr1_+_165631199 0.29 ENST00000367888.8
ENST00000367889.8
ENST00000367885.5
ENST00000367884.6
microsomal glutathione S-transferase 3
chr22_+_41976760 0.29 ENST00000396426.7
ENST00000406029.5
septin 3
chr7_-_72966953 0.29 ENST00000395244.5
tripartite motif containing 74
chr4_-_21697755 0.29 ENST00000382148.7
potassium voltage-gated channel interacting protein 4
chr7_+_90211686 0.28 ENST00000287908.7
ENST00000394621.7
ENST00000394626.5
STEAP2 metalloreductase
chr1_+_161225939 0.28 ENST00000545897.5
translocase of outer mitochondrial membrane 40 like
chrX_-_109625161 0.28 ENST00000372101.3
potassium voltage-gated channel subfamily E regulatory subunit 5
chr1_+_161226045 0.28 ENST00000367988.8
translocase of outer mitochondrial membrane 40 like
chr16_+_727246 0.27 ENST00000561546.5
ENST00000564545.1
ENST00000567414.5
ENST00000568141.5
hydroxyacylglutathione hydrolase like
chr3_+_51942323 0.27 ENST00000431474.6
ENST00000417220.6
ENST00000398755.8
ENST00000471971.6
poly(ADP-ribose) polymerase family member 3
chr11_-_132943671 0.27 ENST00000331898.11
opioid binding protein/cell adhesion molecule like
chr22_+_29719996 0.27 ENST00000216144.4
calcium binding protein 7
chr2_-_32265732 0.27 ENST00000360906.9
ENST00000342905.10
NLR family CARD domain containing 4
chr19_+_35138778 0.27 ENST00000351325.9
ENST00000586871.5
ENST00000592174.1
FXYD domain containing ion transport regulator 1
novel transcript
chr20_+_56358938 0.26 ENST00000371384.4
ENST00000437418.1
family with sequence similarity 210 member B
chr1_-_205750167 0.26 ENST00000367142.5
nuclear casein kinase and cyclin dependent kinase substrate 1
chr15_+_43517590 0.26 ENST00000300231.6
microtubule associated protein 1A
chr22_+_31753867 0.26 ENST00000535622.6
ENST00000645693.1
ENST00000642974.1
ENST00000645711.1
ENST00000644331.1
ENST00000645560.1
ENST00000437411.6
ENST00000433147.2
ENST00000646755.1
ENST00000382112.8
ENST00000647438.1
ENST00000400248.7
ENST00000456178.6
ENST00000646969.1
ENST00000642696.1
ENST00000647343.1
ENST00000400242.8
ENST00000651528.2
ENST00000645015.1
ENST00000645564.1
ENST00000646465.1
ENST00000400249.7
DEP domain containing 5, GATOR1 subcomplex subunit
chr19_+_16661121 0.26 ENST00000187762.7
ENST00000599479.1
transmembrane protein 38A
chr10_+_91162958 0.26 ENST00000614189.4
polycomb group ring finger 5
chr6_+_70667863 0.26 ENST00000370455.8
small ArfGAP 1
chr17_-_69150062 0.25 ENST00000522787.5
ENST00000521538.5
ATP binding cassette subfamily A member 10
chr8_-_92095627 0.25 ENST00000517919.5
ENST00000617740.4
ENST00000613302.4
ENST00000436581.6
ENST00000614812.4
ENST00000519847.5
RUNX1 partner transcriptional co-repressor 1
chr8_-_77000070 0.25 ENST00000357039.9
peroxisomal biogenesis factor 2
chr19_-_36152427 0.25 ENST00000589154.1
ENST00000292907.8
cytochrome c oxidase subunit 7A1
chr19_-_40425982 0.25 ENST00000357949.5
SERTA domain containing 1
chr21_-_33915762 0.25 ENST00000290299.7
ATP synthase peripheral stalk subunit OSCP
chr17_+_76726948 0.25 ENST00000586200.1
methyltransferase like 23
chr9_-_32573173 0.25 ENST00000366466.5
NADH:ubiquinone oxidoreductase subunit B6
chr11_-_132943092 0.24 ENST00000612177.4
ENST00000541867.5
opioid binding protein/cell adhesion molecule like
chr17_-_43942472 0.24 ENST00000225992.8
pancreatic polypeptide
chrX_-_154486578 0.24 ENST00000630530.1
ENST00000369660.9
ENST00000369653.8
ubiquitin like 4A
chr8_-_31033582 0.24 ENST00000339382.3
ENST00000475541.2
purine rich element binding protein G
chr18_-_5544250 0.24 ENST00000540638.6
ENST00000342933.7
erythrocyte membrane protein band 4.1 like 3
chr12_-_100262356 0.24 ENST00000548313.5
DEP domain containing 4
chr2_-_237414157 0.24 ENST00000295550.9
ENST00000353578.9
ENST00000392004.7
ENST00000433762.1
ENST00000392003.6
collagen type VI alpha 3 chain
chr5_+_162067990 0.24 ENST00000641017.1
gamma-aminobutyric acid type A receptor subunit gamma2
chr1_+_26993684 0.24 ENST00000522111.3
TMF1 regulated nuclear protein 1
chr19_-_39335999 0.24 ENST00000602185.5
ENST00000598034.5
ENST00000601387.5
ENST00000595636.1
ENST00000253054.12
ENST00000594700.5
ENST00000597595.6
glia maturation factor gamma
chr11_+_71999603 0.24 ENST00000260049.9
interleukin 18 binding protein
chr3_-_42804451 0.24 ENST00000418900.6
ENST00000321331.12
ENST00000430190.5
ENST00000648550.1
HIG1 hypoxia inducible domain family member 1A
novel protein
chr17_+_76726827 0.24 ENST00000589977.5
ENST00000615984.4
ENST00000591571.5
ENST00000341249.11
ENST00000592849.5
ENST00000586738.5
ENST00000588783.5
ENST00000588563.5
ENST00000586752.5
ENST00000588302.5
ENST00000590964.5
ENST00000588822.1
methyltransferase like 23
chr7_+_151085858 0.24 ENST00000463381.5
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr8_+_143267435 0.23 ENST00000521682.5
ENST00000340042.2
GLI family zinc finger 4
chr5_+_162068031 0.23 ENST00000356592.8
gamma-aminobutyric acid type A receptor subunit gamma2
chr11_-_111923722 0.23 ENST00000527950.5
crystallin alpha B
chr8_-_130016395 0.23 ENST00000523509.5
CYFIP related Rac1 interactor B
chr2_+_6865557 0.23 ENST00000680607.1
ENST00000680320.1
ENST00000442639.6
radical S-adenosyl methionine domain containing 2
chr8_-_130016414 0.23 ENST00000401979.6
ENST00000517654.5
ENST00000522361.1
ENST00000518167.5
CYFIP related Rac1 interactor B
chr19_+_11239602 0.23 ENST00000252453.12
angiopoietin like 8
chr19_+_35030438 0.23 ENST00000415950.5
ENST00000262631.11
sodium voltage-gated channel beta subunit 1
chrX_-_31178149 0.23 ENST00000679437.1
dystrophin

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.7 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.4 1.3 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.3 0.9 GO:0021503 neural fold bending(GO:0021503)
0.3 2.7 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.2 0.7 GO:0009386 translational attenuation(GO:0009386)
0.2 1.0 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.2 0.7 GO:0060367 subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875)
0.2 0.7 GO:0006106 fumarate metabolic process(GO:0006106)
0.2 0.7 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.2 0.8 GO:1903352 L-ornithine transmembrane transport(GO:1903352)
0.1 0.6 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.6 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.4 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.1 0.5 GO:2000983 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)
0.1 0.2 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.1 0.3 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.1 0.4 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.4 GO:0030961 peptidyl-arginine hydroxylation(GO:0030961)
0.1 0.5 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.9 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.4 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.1 0.3 GO:0060382 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.1 0.3 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 0.3 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.1 0.4 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 0.2 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.5 GO:0008218 bioluminescence(GO:0008218)
0.1 0.6 GO:0061709 reticulophagy(GO:0061709)
0.1 0.8 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 0.3 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.1 0.6 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 0.2 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1 0.4 GO:1903998 regulation of eating behavior(GO:1903998)
0.1 0.8 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.4 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.1 0.6 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 0.1 GO:0002339 B cell selection(GO:0002339)
0.1 0.2 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1 0.5 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.1 0.2 GO:0051695 actin filament uncapping(GO:0051695)
0.1 1.2 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.1 0.5 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.2 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.1 1.0 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.5 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1 0.3 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.1 0.2 GO:0071284 cellular response to lead ion(GO:0071284)
0.1 0.3 GO:0009644 response to high light intensity(GO:0009644)
0.1 0.2 GO:1990258 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.1 0.2 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1 0.4 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.1 0.4 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.1 GO:0003192 mitral valve formation(GO:0003192)
0.0 1.1 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 2.3 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.1 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.0 0.2 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.3 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 0.6 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.3 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 1.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.7 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.3 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.1 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.0 0.3 GO:0070269 pyroptosis(GO:0070269)
0.0 0.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.2 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.3 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.4 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.4 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.2 GO:1904304 regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.0 0.1 GO:0043465 fermentation(GO:0006113) regulation of fermentation(GO:0043465)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.1 GO:2000314 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0 0.5 GO:0042407 cristae formation(GO:0042407)
0.0 0.6 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.1 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.0 0.1 GO:0052509 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.0 0.5 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.3 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:0006480 N-terminal protein amino acid methylation(GO:0006480) N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573)
0.0 0.1 GO:1901671 positive regulation of superoxide dismutase activity(GO:1901671) regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) negative regulation of DNA catabolic process(GO:1903625) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634) positive regulation of removal of superoxide radicals(GO:1904833)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.4 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:2000296 regulation of hydrogen peroxide catabolic process(GO:2000295) negative regulation of hydrogen peroxide catabolic process(GO:2000296) regulation of oxygen metabolic process(GO:2000374)
0.0 0.4 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.4 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.5 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.2 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.5 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.1 GO:0033133 regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0 0.6 GO:1900116 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.4 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.0 GO:0070256 negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.3 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 1.6 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.3 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.3 GO:0007144 female meiosis I(GO:0007144)
0.0 0.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.3 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.6 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 1.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0035565 regulation of pronephros size(GO:0035565)
0.0 0.2 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 0.6 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.4 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.5 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.3 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.3 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.4 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.2 GO:0061525 hindgut development(GO:0061525)
0.0 0.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.1 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.0 0.2 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.0 GO:0033076 isoquinoline alkaloid metabolic process(GO:0033076) phytoalexin metabolic process(GO:0052314)
0.0 0.1 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.4 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0097327 response to antineoplastic agent(GO:0097327)
0.0 0.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.0 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.3 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.4 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.0 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363)
0.0 0.1 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.5 GO:0097237 cellular response to toxic substance(GO:0097237)
0.0 0.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0 0.1 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.1 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.0 GO:0030472 mitotic spindle organization in nucleus(GO:0030472)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.2 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.2 GO:0050746 regulation of lipoprotein metabolic process(GO:0050746)
0.0 0.2 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.0 0.4 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.3 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.2 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.4 GO:0042026 protein refolding(GO:0042026)
0.0 0.3 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 1.3 GO:0070126 mitochondrial translational termination(GO:0070126)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 0.0 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 0.0 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.1 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.5 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.7 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.4 GO:0016939 kinesin II complex(GO:0016939)
0.1 0.6 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.5 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 1.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.8 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.2 GO:0005745 m-AAA complex(GO:0005745)
0.1 1.1 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.4 GO:0032021 NELF complex(GO:0032021)
0.1 0.2 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.4 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.2 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.0 0.4 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.5 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.3 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 1.0 GO:0033270 paranode region of axon(GO:0033270)
0.0 3.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0043291 RAVE complex(GO:0043291)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.4 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.4 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.2 GO:0001651 dense fibrillar component(GO:0001651)
0.0 0.1 GO:0071752 dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752)
0.0 0.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.0 0.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.4 GO:0097433 dense body(GO:0097433)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.6 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 1.4 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 1.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.0 GO:0031430 M band(GO:0031430)
0.0 1.0 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 0.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.4 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.3 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.7 GO:0097542 ciliary tip(GO:0097542)
0.0 1.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.8 GO:0005871 kinesin complex(GO:0005871)
0.0 0.0 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0097450 astrocyte end-foot(GO:0097450)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0008893 guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity(GO:0008893) diphosphoric monoester hydrolase activity(GO:0016794)
0.4 3.7 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 0.6 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.2 0.6 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.2 0.6 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.4 GO:0042007 interleukin-18 binding(GO:0042007)
0.1 0.4 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.1 0.3 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.6 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.3 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.8 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.5 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.4 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.1 1.1 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.1 0.6 GO:0004771 sterol esterase activity(GO:0004771)
0.1 1.0 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.6 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.4 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.7 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1 1.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.2 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 0.2 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.1 1.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.2 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.4 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.6 GO:0015288 porin activity(GO:0015288)
0.1 0.2 GO:0036009 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.1 0.2 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.3 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.3 GO:0005499 vitamin D binding(GO:0005499)
0.0 1.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.7 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 1.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.3 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.2 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0033265 choline binding(GO:0033265)
0.0 0.2 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.3 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.0 0.3 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.3 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.7 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.4 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.4 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.5 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.1 GO:0004341 gluconolactonase activity(GO:0004341)
0.0 0.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 1.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 3.8 GO:0051087 chaperone binding(GO:0051087)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0032440 2-alkenal reductase [NAD(P)] activity(GO:0032440)
0.0 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 1.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.3 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.3 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 1.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.0 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.1 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.0 0.4 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.2 GO:0036122 BMP binding(GO:0036122)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.4 GO:0046961 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.8 GO:0003777 microtubule motor activity(GO:0003777)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.2 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.1 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.8 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 1.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 2.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.5 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 1.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.6 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.1 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.5 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 1.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors