Project
Inflammatory response time course, HUVEC (Wada, 2009)
Navigation
Downloads
Results for ETV3
Z-value: 1.19
Motif logo
Transcription factors associated with ETV3
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ETV3 | hg38_v1_chr1_-_157138388_157138402 | -0.25 | 2.3e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of ETV3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 13.1 | GO:0043101 | purine-containing compound salvage(GO:0043101) |
| 0.3 | 6.7 | GO:0070914 | UV-damage excision repair(GO:0070914) |
| 2.1 | 6.2 | GO:0071988 | regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846) |
| 1.1 | 5.7 | GO:0098904 | regulation of AV node cell action potential(GO:0098904) |
| 0.1 | 5.1 | GO:2000300 | regulation of synaptic vesicle exocytosis(GO:2000300) |
| 0.6 | 4.4 | GO:0018317 | protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406) |
| 0.2 | 3.6 | GO:0016558 | protein import into peroxisome matrix(GO:0016558) |
| 0.1 | 3.5 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
| 0.0 | 3.2 | GO:0006626 | protein targeting to mitochondrion(GO:0006626) |
| 0.6 | 3.1 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.6 | 13.1 | GO:1902560 | GMP reductase complex(GO:1902560) |
| 0.1 | 11.8 | GO:0031902 | late endosome membrane(GO:0031902) |
| 2.1 | 6.2 | GO:0055028 | cortical microtubule(GO:0055028) |
| 0.5 | 5.8 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.2 | 5.7 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.0 | 4.7 | GO:0019866 | organelle inner membrane(GO:0019866) |
| 0.0 | 4.3 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.3 | 4.2 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.0 | 3.0 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.1 | 2.8 | GO:0071564 | npBAF complex(GO:0071564) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.6 | 13.1 | GO:0003920 | GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657) |
| 0.1 | 7.5 | GO:0003684 | damaged DNA binding(GO:0003684) |
| 0.5 | 6.6 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.6 | 5.7 | GO:0071253 | connexin binding(GO:0071253) |
| 0.0 | 5.4 | GO:0008094 | DNA-dependent ATPase activity(GO:0008094) |
| 0.2 | 5.1 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
| 0.1 | 4.3 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
| 0.0 | 4.0 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.0 | 3.1 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.6 | 2.9 | GO:0032810 | sterol response element binding(GO:0032810) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.3 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 5.0 | PID E2F PATHWAY | E2F transcription factor network |
| 0.1 | 2.9 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 2.5 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 2.3 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 2.1 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.0 | 1.3 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 1.3 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 0.8 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 0.8 | PID MYC PATHWAY | C-MYC pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 13.1 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.4 | 6.2 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.1 | 5.9 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.1 | 5.7 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.1 | 4.3 | REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX | Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex |
| 0.0 | 2.9 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.1 | 2.7 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.1 | 2.6 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.1 | 2.5 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.1 | 2.2 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |