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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for EVX2

Z-value: 0.30

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Transcription factors associated with EVX2

Gene Symbol Gene ID Gene Info
ENSG00000174279.4 EVX2

Activity profile of EVX2 motif

Sorted Z-values of EVX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of EVX2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr15_-_55270280 0.48 ENST00000564609.5
RAB27A, member RAS oncogene family
chr15_-_55270383 0.45 ENST00000396307.6
RAB27A, member RAS oncogene family
chr15_-_55270874 0.44 ENST00000567380.5
ENST00000565972.5
ENST00000569493.5
RAB27A, member RAS oncogene family
chr4_+_143433491 0.42 ENST00000512843.1
GRB2 associated binding protein 1
chr3_+_111999326 0.37 ENST00000494932.1
transgelin 3
chr3_+_111998739 0.36 ENST00000393917.6
ENST00000273368.8
transgelin 3
chr3_+_111999189 0.35 ENST00000455401.6
transgelin 3
chr3_+_111998915 0.35 ENST00000478951.6
transgelin 3
chr6_-_62286161 0.32 ENST00000281156.5
KH RNA binding domain containing, signal transduction associated 2
chr1_+_160190567 0.31 ENST00000368078.8
calsequestrin 1
chr20_-_51802509 0.23 ENST00000371539.7
ENST00000217086.9
spalt like transcription factor 4
chr5_+_141484997 0.20 ENST00000617094.1
ENST00000306593.2
ENST00000610539.1
ENST00000618371.4
protocadherin gamma subfamily C, 4
chr20_-_51802433 0.16 ENST00000395997.3
spalt like transcription factor 4
chr4_-_145180496 0.15 ENST00000447906.8
OTU deubiquitinase 4
chr4_+_94974984 0.15 ENST00000672698.1
bone morphogenetic protein receptor type 1B
chr1_+_27934980 0.15 ENST00000373894.8
sphingomyelin phosphodiesterase acid like 3B
chr12_-_53336342 0.15 ENST00000537210.2
ENST00000536324.4
Sp7 transcription factor
chr1_+_27935110 0.14 ENST00000549094.1
sphingomyelin phosphodiesterase acid like 3B
chr1_+_27935022 0.14 ENST00000411604.5
ENST00000373888.8
sphingomyelin phosphodiesterase acid like 3B
chr11_+_65787056 0.13 ENST00000335987.8
ovo like transcriptional repressor 1
chr6_+_132538290 0.12 ENST00000434551.2
trace amine associated receptor 9
chr20_+_31879798 0.09 ENST00000620043.4
tubulin tyrosine ligase like 9
chr12_+_15546344 0.09 ENST00000674388.1
ENST00000542557.5
ENST00000445537.6
ENST00000544244.5
ENST00000442921.7
protein tyrosine phosphatase receptor type O
chr12_+_119668109 0.07 ENST00000229328.10
ENST00000630317.1
protein kinase AMP-activated non-catalytic subunit beta 1
chr8_+_7926337 0.07 ENST00000400120.3
zinc finger protein 705B
chr8_+_91249307 0.05 ENST00000309536.6
ENST00000276609.8
solute carrier family 26 member 7
chr17_-_10026265 0.03 ENST00000437099.6
ENST00000396115.6
growth arrest specific 7
chr5_-_97142579 0.03 ENST00000274382.9
limb and CNS expressed 1
chr11_-_115504389 0.02 ENST00000545380.5
ENST00000452722.7
ENST00000331581.11
ENST00000537058.5
ENST00000536727.5
ENST00000542447.6
cell adhesion molecule 1
chr17_+_18183052 0.01 ENST00000541285.1
alkB homolog 5, RNA demethylase
chr21_-_31160904 0.00 ENST00000636887.1
TIAM Rac1 associated GEF 1
chr4_-_73620629 0.00 ENST00000342081.7
Ras association domain family member 6
chr16_+_53099100 0.00 ENST00000565832.5
chromodomain helicase DNA binding protein 9

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.1 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.3 GO:0014877 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.0 0.4 GO:0035728 response to hepatocyte growth factor(GO:0035728)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.3 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR