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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for FOSL1

Z-value: 1.17

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Transcription factors associated with FOSL1

Gene Symbol Gene ID Gene Info
FOSL1
ENSG00000175592.9 FOSL1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOSL1hg38_v1_chr11_-_65900375_659003970.892.8e-09Click!

Activity profile of FOSL1 motif

Sorted Z-values of FOSL1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSL1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_+_73740541 8.01 ENST00000401931.1
ENST00000307407.8
CXCL8
C-X-C motif chemokine ligand 8
chr1_+_183186238 7.85 ENST00000493293.5
ENST00000264144.5
LAMC2
laminin subunit gamma 2
chr15_+_88638947 7.71 ENST00000559876.2
ISG20
interferon stimulated exonuclease gene 20
chr11_-_102798148 7.11 ENST00000315274.7
MMP1
matrix metallopeptidase 1
chr1_-_94541636 7.09 ENST00000370207.4
F3
coagulation factor III, tissue factor
chr1_-_94541746 7.05 ENST00000334047.12
F3
coagulation factor III, tissue factor
chr2_+_151357583 6.79 ENST00000243347.5
TNFAIP6
TNF alpha induced protein 6
chr15_+_88639009 6.60 ENST00000306072.10
ISG20
interferon stimulated exonuclease gene 20
chr1_-_153549120 6.33 ENST00000368712.1
S100A3
S100 calcium binding protein A3
chr1_-_153549238 5.59 ENST00000368713.8
S100A3
S100 calcium binding protein A3
chr5_+_35856883 4.98 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
IL7R
interleukin 7 receptor
chr18_+_63887698 4.95 ENST00000457692.5
ENST00000299502.9
ENST00000413956.5
SERPINB2
serpin family B member 2
chr10_-_5978022 4.49 ENST00000525219.6
IL15RA
interleukin 15 receptor subunit alpha
chr10_-_5977589 4.40 ENST00000620345.4
ENST00000397251.7
ENST00000397248.6
ENST00000622442.4
ENST00000620865.4
IL15RA
interleukin 15 receptor subunit alpha
chr10_-_5977535 4.35 ENST00000379977.8
IL15RA
interleukin 15 receptor subunit alpha
chr6_+_137867241 4.11 ENST00000612899.5
ENST00000420009.5
TNFAIP3
TNF alpha induced protein 3
chr6_+_137867414 4.10 ENST00000237289.8
ENST00000433680.1
TNFAIP3
TNF alpha induced protein 3
chr1_-_7940825 4.04 ENST00000377507.8
TNFRSF9
TNF receptor superfamily member 9
chr10_+_102395693 3.81 ENST00000652277.1
ENST00000189444.11
ENST00000661543.1
NFKB2
nuclear factor kappa B subunit 2
chr17_+_21288029 3.60 ENST00000526076.6
ENST00000361818.9
ENST00000316920.10
MAP2K3
mitogen-activated protein kinase kinase 3
chr6_-_44265541 3.57 ENST00000619360.6
NFKBIE
NFKB inhibitor epsilon
chr12_-_104958268 3.36 ENST00000432951.1
ENST00000258538.8
ENST00000415674.1
ENST00000424946.1
ENST00000433540.5
SLC41A2
solute carrier family 41 member 2
chr4_-_121164314 3.32 ENST00000057513.8
TNIP3
TNFAIP3 interacting protein 3
chr1_+_156114700 3.22 ENST00000677389.1
ENST00000368300.9
ENST00000368299.7
LMNA
lamin A/C
chr17_+_76385256 3.14 ENST00000392496.3
SPHK1
sphingosine kinase 1
chr11_+_35176611 3.10 ENST00000279452.10
CD44
CD44 molecule (Indian blood group)
chr1_+_156114251 3.02 ENST00000361308.9
LMNA
lamin A/C
chr1_+_155135344 3.01 ENST00000484157.5
SLC50A1
solute carrier family 50 member 1
chr21_-_35049238 2.99 ENST00000416754.1
ENST00000437180.5
ENST00000455571.5
ENST00000675419.1
RUNX1
RUNX family transcription factor 1
chr10_-_5977492 2.89 ENST00000530685.5
ENST00000397255.7
ENST00000379971.5
ENST00000528354.5
ENST00000397250.6
ENST00000429135.2
IL15RA
interleukin 15 receptor subunit alpha
chr21_-_35049327 2.89 ENST00000300305.7
RUNX1
RUNX family transcription factor 1
chr11_+_35176696 2.83 ENST00000528455.5
CD44
CD44 molecule (Indian blood group)
chr12_-_55842950 2.79 ENST00000548629.5
MMP19
matrix metallopeptidase 19
chr5_+_136058849 2.76 ENST00000508076.5
TGFBI
transforming growth factor beta induced
chr11_-_65900375 2.74 ENST00000312562.7
FOSL1
FOS like 1, AP-1 transcription factor subunit
chr11_-_65900413 2.74 ENST00000448083.6
ENST00000531493.5
ENST00000532401.1
FOSL1
FOS like 1, AP-1 transcription factor subunit
chr11_-_65662780 2.63 ENST00000534283.1
ENST00000527749.5
ENST00000533187.5
ENST00000525693.5
ENST00000534558.5
ENST00000532879.5
ENST00000406246.8
ENST00000532999.5
RELA
RELA proto-oncogene, NF-kB subunit
chr11_+_35176639 2.60 ENST00000527889.6
CD44
CD44 molecule (Indian blood group)
chr11_+_35176575 2.48 ENST00000526000.6
CD44
CD44 molecule (Indian blood group)
chr6_-_138107412 2.43 ENST00000421351.4
PERP
p53 apoptosis effector related to PMP22
chr11_-_2929412 2.42 ENST00000314222.5
PHLDA2
pleckstrin homology like domain family A member 2
chr8_+_125430333 2.39 ENST00000311922.4
TRIB1
tribbles pseudokinase 1
chr1_-_209651291 2.28 ENST00000391911.5
ENST00000415782.1
LAMB3
laminin subunit beta 3
chrX_-_155334580 2.23 ENST00000369449.7
ENST00000321926.4
CLIC2
chloride intracellular channel 2
chr8_+_85245451 2.15 ENST00000321764.4
CA13
carbonic anhydrase 13
chr18_+_58221535 2.14 ENST00000431212.6
ENST00000586268.5
ENST00000587190.5
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr17_+_81683963 2.10 ENST00000676462.1
ENST00000679336.1
ENST00000678196.1
ENST00000677243.1
ENST00000677044.1
ENST00000677109.1
ENST00000677484.1
ENST00000678105.1
ENST00000677209.1
ENST00000329138.9
ENST00000677225.1
ENST00000678866.1
ENST00000676729.1
ENST00000572392.2
ENST00000577012.1
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr1_-_6602885 1.99 ENST00000377663.3
KLHL21
kelch like family member 21
chr1_-_150235972 1.98 ENST00000534220.1
ANP32E
acidic nuclear phosphoprotein 32 family member E
chr17_-_47851155 1.91 ENST00000536300.2
SP6
Sp6 transcription factor
chr1_-_6602859 1.86 ENST00000377658.8
KLHL21
kelch like family member 21
chr17_+_4950147 1.86 ENST00000522301.5
ENO3
enolase 3
chr11_-_65663083 1.85 ENST00000308639.13
RELA
RELA proto-oncogene, NF-kB subunit
chr7_+_143381286 1.83 ENST00000449630.5
ENST00000322764.10
ENST00000457235.5
ZYX
zyxin
chr17_-_29930062 1.81 ENST00000579954.1
ENST00000269033.7
ENST00000540801.6
ENST00000590153.1
ENST00000582084.1
SSH2
slingshot protein phosphatase 2
chr1_-_12616762 1.76 ENST00000464917.5
DHRS3
dehydrogenase/reductase 3
chr16_+_57628507 1.75 ENST00000456916.5
ENST00000567154.5
ENST00000388813.9
ENST00000562558.6
ENST00000566271.6
ENST00000563374.5
ENST00000673126.2
ENST00000562631.7
ENST00000568234.5
ENST00000565770.5
ENST00000566164.5
ADGRG1
adhesion G protein-coupled receptor G1
chr11_+_35618450 1.72 ENST00000317811.6
FJX1
four-jointed box kinase 1
chr6_+_82363199 1.72 ENST00000535040.4
TPBG
trophoblast glycoprotein
chr18_+_63970029 1.71 ENST00000353706.6
ENST00000542677.5
ENST00000397985.7
ENST00000636430.1
ENST00000397988.7
ENST00000448851.5
SERPINB8
serpin family B member 8
chr7_+_28685968 1.70 ENST00000396298.6
CREB5
cAMP responsive element binding protein 5
chr16_+_56608577 1.66 ENST00000245185.6
ENST00000561491.1
MT2A
metallothionein 2A
chr10_+_24466487 1.62 ENST00000396446.5
ENST00000396445.5
ENST00000376451.4
KIAA1217
KIAA1217
chr11_-_65662931 1.61 ENST00000615805.4
ENST00000612991.4
RELA
RELA proto-oncogene, NF-kB subunit
chr10_-_25062279 1.57 ENST00000615958.4
ENKUR
enkurin, TRPC channel interacting protein
chr2_+_102418642 1.56 ENST00000264260.6
IL18RAP
interleukin 18 receptor accessory protein
chr6_-_43629222 1.51 ENST00000307126.10
GTPBP2
GTP binding protein 2
chr17_-_41140487 1.49 ENST00000345847.4
KRTAP4-6
keratin associated protein 4-6
chr1_+_156126525 1.49 ENST00000504687.6
ENST00000473598.6
LMNA
lamin A/C
chr9_+_35673917 1.44 ENST00000617161.1
ENST00000378357.9
CA9
carbonic anhydrase 9
chr6_+_150721073 1.43 ENST00000358517.6
PLEKHG1
pleckstrin homology and RhoGEF domain containing G1
chr18_+_58196736 1.43 ENST00000675221.1
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr6_+_106098933 1.41 ENST00000369089.3
PRDM1
PR/SET domain 1
chr12_-_214146 1.37 ENST00000684302.1
SLC6A12
solute carrier family 6 member 12
chr6_-_46325641 1.34 ENST00000330430.10
ENST00000405162.2
RCAN2
regulator of calcineurin 2
chr6_-_169250825 1.28 ENST00000676869.1
ENST00000676760.1
THBS2
thrombospondin 2
chrX_-_111270474 1.28 ENST00000324068.2
CAPN6
calpain 6
chr5_+_179820895 1.28 ENST00000504627.1
ENST00000389805.9
ENST00000510187.5
SQSTM1
sequestosome 1
chr6_+_45328203 1.26 ENST00000371432.7
ENST00000647337.2
ENST00000371438.5
RUNX2
RUNX family transcription factor 2
chr19_+_38304105 1.26 ENST00000588605.5
ENST00000301246.10
C19orf33
chromosome 19 open reading frame 33
chr16_+_57628684 1.23 ENST00000567397.5
ENST00000568979.5
ENST00000672974.1
ADGRG1
adhesion G protein-coupled receptor G1
chr10_-_30999469 1.22 ENST00000538351.6
ZNF438
zinc finger protein 438
chr3_+_30606574 1.21 ENST00000295754.10
ENST00000359013.4
TGFBR2
transforming growth factor beta receptor 2
chr21_-_26843012 1.20 ENST00000517777.6
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr18_-_49557 1.19 ENST00000308911.8
TUBB8B
tubulin beta 8B
chr5_-_60488055 1.16 ENST00000505507.6
ENST00000515835.2
ENST00000502484.6
PDE4D
phosphodiesterase 4D
chr17_+_76265332 1.16 ENST00000327490.8
ENST00000587913.1
UBALD2
UBA like domain containing 2
chr1_+_150149819 1.15 ENST00000369124.5
PLEKHO1
pleckstrin homology domain containing O1
chr21_-_26843063 1.14 ENST00000678221.1
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr12_+_6914571 1.13 ENST00000229277.6
ENST00000538763.5
ENST00000545045.6
ENO2
enolase 2
chr1_-_150235943 1.13 ENST00000533654.5
ANP32E
acidic nuclear phosphoprotein 32 family member E
chr6_-_83431038 1.09 ENST00000369705.4
ME1
malic enzyme 1
chr19_+_35030711 1.08 ENST00000595652.5
SCN1B
sodium voltage-gated channel beta subunit 1
chr12_-_55842927 1.08 ENST00000322569.9
ENST00000409200.7
MMP19
matrix metallopeptidase 19
chr22_-_30246739 1.07 ENST00000403987.3
ENST00000249075.4
LIF
LIF interleukin 6 family cytokine
chr1_-_112704921 1.05 ENST00000414971.1
ENST00000534717.5
RHOC
ras homolog family member C
chr6_+_138161932 1.05 ENST00000251691.5
ARFGEF3
ARFGEF family member 3
chr5_+_148203024 1.04 ENST00000325630.3
SPINK6
serine peptidase inhibitor Kazal type 6
chr22_+_39520553 1.03 ENST00000674920.3
ENST00000679776.1
ENST00000675582.2
ENST00000337304.2
ENST00000676346.2
ENST00000396680.3
ENST00000680446.1
ENST00000674568.2
ENST00000680748.1
ENST00000674835.2
ATF4
activating transcription factor 4
chr16_+_88453260 1.03 ENST00000319555.8
ZFPM1
zinc finger protein, FOG family member 1
chr14_-_52791597 1.01 ENST00000216410.8
ENST00000557604.1
GNPNAT1
glucosamine-phosphate N-acetyltransferase 1
chr1_+_156126160 1.00 ENST00000448611.6
ENST00000368297.5
LMNA
lamin A/C
chr15_-_70096604 0.99 ENST00000559048.5
ENST00000560939.5
ENST00000440567.7
ENST00000557907.5
ENST00000558379.5
ENST00000559929.5
TLE3
TLE family member 3, transcriptional corepressor
chr3_-_191282383 0.98 ENST00000427544.6
UTS2B
urotensin 2B
chrX_-_130110679 0.97 ENST00000335997.11
ELF4
E74 like ETS transcription factor 4
chr4_-_165279679 0.96 ENST00000505354.2
GK3P
glycerol kinase 3 pseudogene
chr22_+_20507571 0.96 ENST00000414658.5
ENST00000432052.5
ENST00000292733.11
ENST00000263205.11
ENST00000406969.5
MED15
mediator complex subunit 15
chr3_-_37174578 0.96 ENST00000336686.9
LRRFIP2
LRR binding FLII interacting protein 2
chr1_-_150235995 0.95 ENST00000436748.6
ANP32E
acidic nuclear phosphoprotein 32 family member E
chr6_-_35921047 0.93 ENST00000361690.7
ENST00000512445.5
SRPK1
SRSF protein kinase 1
chr11_-_76669985 0.91 ENST00000407242.6
ENST00000421973.1
LRRC32
leucine rich repeat containing 32
chr10_+_30434176 0.91 ENST00000263056.6
ENST00000375322.2
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr8_-_69833338 0.91 ENST00000524945.5
SLCO5A1
solute carrier organic anion transporter family member 5A1
chr1_-_28193873 0.90 ENST00000305392.3
ENST00000539896.1
PTAFR
platelet activating factor receptor
chr7_+_128455849 0.89 ENST00000435296.2
ENST00000257696.5
HILPDA
hypoxia inducible lipid droplet associated
chr8_-_27258414 0.88 ENST00000523048.5
STMN4
stathmin 4
chr6_+_25652201 0.88 ENST00000612225.4
ENST00000377961.3
SCGN
secretagogin, EF-hand calcium binding protein
chrX_-_49079702 0.87 ENST00000636049.1
ENST00000474053.6
ENST00000635003.1
WDR45
WD repeat domain 45
chr10_+_30434021 0.86 ENST00000542547.5
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr15_-_70096260 0.85 ENST00000558201.5
TLE3
TLE family member 3, transcriptional corepressor
chr4_-_99657820 0.85 ENST00000511828.2
C4orf54
chromosome 4 open reading frame 54
chr19_+_38390055 0.85 ENST00000587947.5
ENST00000338502.8
SPRED3
sprouty related EVH1 domain containing 3
chr1_-_159924529 0.84 ENST00000320307.8
TAGLN2
transgelin 2
chr16_-_31150058 0.84 ENST00000569305.1
ENST00000268281.9
ENST00000418068.6
PRSS36
serine protease 36
chr10_-_49269 0.83 ENST00000562809.1
ENST00000568866.5
ENST00000561967.1
ENST00000568584.6
TUBB8
tubulin beta 8 class VIII
chr7_+_148698857 0.83 ENST00000663835.1
ENST00000655324.1
ENST00000662132.1
ENST00000666124.1
ENST00000325222.9
ENST00000660240.1
CUL1
cullin 1
chrX_-_130110479 0.83 ENST00000308167.10
ELF4
E74 like ETS transcription factor 4
chr10_-_79949098 0.82 ENST00000372292.8
SFTPD
surfactant protein D
chr18_+_58341038 0.82 ENST00000679791.1
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr11_-_3840942 0.81 ENST00000351018.5
RHOG
ras homolog family member G
chr19_-_45782388 0.80 ENST00000458663.6
DMPK
DM1 protein kinase
chr11_-_9003994 0.79 ENST00000309166.8
ENST00000525100.1
ENST00000531090.5
NRIP3
nuclear receptor interacting protein 3
chr6_-_35921079 0.78 ENST00000507909.1
ENST00000373825.7
SRPK1
SRSF protein kinase 1
chr19_-_10339610 0.78 ENST00000589261.5
ENST00000160262.10
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
ICAM3
intercellular adhesion molecule 3
chr19_-_45782479 0.77 ENST00000447742.6
ENST00000354227.9
ENST00000291270.9
ENST00000683086.1
ENST00000343373.10
DMPK
DM1 protein kinase
chr2_+_68974573 0.77 ENST00000673932.3
ENST00000377938.4
GKN1
gastrokine 1
chr19_+_35154715 0.76 ENST00000392218.6
ENST00000543307.5
ENST00000392219.7
ENST00000541435.6
ENST00000590686.5
ENST00000342879.7
ENST00000588699.5
FXYD5
FXYD domain containing ion transport regulator 5
chr6_-_35921128 0.75 ENST00000510290.5
ENST00000423325.6
SRPK1
SRSF protein kinase 1
chr1_-_27490130 0.75 ENST00000618852.5
WASF2
WASP family member 2
chr9_-_35111573 0.75 ENST00000378561.5
ENST00000603301.5
FAM214B
family with sequence similarity 214 member B
chr19_+_35154914 0.74 ENST00000423817.7
FXYD5
FXYD domain containing ion transport regulator 5
chr3_-_11568764 0.74 ENST00000424529.6
VGLL4
vestigial like family member 4
chr12_-_53232182 0.72 ENST00000425354.7
ENST00000546717.1
ENST00000394426.5
RARG
retinoic acid receptor gamma
chr17_-_40755328 0.71 ENST00000312150.5
KRT25
keratin 25
chr1_+_36155930 0.70 ENST00000316156.8
MAP7D1
MAP7 domain containing 1
chrX_-_154019800 0.69 ENST00000444230.5
ENST00000393687.6
ENST00000429936.6
ENST00000369974.6
ENST00000369980.8
IRAK1
interleukin 1 receptor associated kinase 1
chr9_-_35111423 0.69 ENST00000378557.1
FAM214B
family with sequence similarity 214 member B
chr7_-_151024423 0.69 ENST00000469530.4
ENST00000639579.1
ATG9B
autophagy related 9B
chr1_+_36156096 0.68 ENST00000474796.2
ENST00000373150.8
ENST00000373151.6
MAP7D1
MAP7 domain containing 1
chr9_-_107489754 0.68 ENST00000610832.1
ENST00000374672.5
KLF4
Kruppel like factor 4
chr11_+_706117 0.68 ENST00000533256.5
ENST00000614442.4
EPS8L2
EPS8 like 2
chr17_+_7351889 0.66 ENST00000576980.2
KCTD11
potassium channel tetramerization domain containing 11
chr1_+_155033824 0.64 ENST00000295542.6
ENST00000423025.6
ENST00000368419.2
DCST1
DC-STAMP domain containing 1
chrX_-_49079872 0.64 ENST00000473974.5
ENST00000475880.6
ENST00000634838.1
ENST00000376372.9
ENST00000476728.5
ENST00000635666.1
ENST00000634559.1
ENST00000322995.13
ENST00000634736.1
ENST00000396681.9
ENST00000471338.6
ENST00000485908.6
ENST00000376368.7
ENST00000376358.4
WDR45
ENSG00000288053.1
WD repeat domain 45
novel protein
chr1_-_150236064 0.63 ENST00000532744.2
ENST00000369114.9
ENST00000369115.3
ENST00000583931.6
ANP32E
acidic nuclear phosphoprotein 32 family member E
chr17_+_7352142 0.63 ENST00000333751.8
KCTD11
potassium channel tetramerization domain containing 11
chr2_+_232697362 0.63 ENST00000482666.5
ENST00000483164.5
ENST00000490229.5
ENST00000464805.5
ENST00000489328.1
GIGYF2
GRB10 interacting GYF protein 2
chr9_-_120877026 0.63 ENST00000436309.5
PHF19
PHD finger protein 19
chr1_-_207051202 0.63 ENST00000315927.9
YOD1
YOD1 deubiquitinase
chrX_+_41333905 0.62 ENST00000457138.7
ENST00000643821.1
DDX3X
DEAD-box helicase 3 X-linked
chr5_+_141489066 0.62 ENST00000252087.3
PCDHGC5
protocadherin gamma subfamily C, 5
chr11_+_35662739 0.61 ENST00000299413.7
TRIM44
tripartite motif containing 44
chr3_+_48466222 0.61 ENST00000625293.3
ENST00000492235.2
ENST00000635452.2
ENST00000456089.1
TREX1
three prime repair exonuclease 1
chr15_-_48963912 0.61 ENST00000332408.9
SHC4
SHC adaptor protein 4
chr2_+_169509693 0.61 ENST00000284669.2
KLHL41
kelch like family member 41
chr2_-_179746040 0.60 ENST00000409343.5
ZNF385B
zinc finger protein 385B
chr22_+_22030934 0.59 ENST00000390282.2
IGLV4-69
immunoglobulin lambda variable 4-69
chr4_-_122621011 0.57 ENST00000611104.2
ENST00000648588.1
IL21
interleukin 21
chr7_+_99408609 0.56 ENST00000403633.6
BUD31
BUD31 homolog
chr6_+_30717433 0.56 ENST00000681435.1
TUBB
tubulin beta class I
chr17_-_58517835 0.56 ENST00000579921.1
ENST00000579925.5
ENST00000323456.9
MTMR4
myotubularin related protein 4
chr6_+_63521738 0.56 ENST00000648894.1
ENST00000639568.2
PTP4A1
protein tyrosine phosphatase 4A1
chr9_+_4985227 0.55 ENST00000381652.4
JAK2
Janus kinase 2
chr17_-_7687427 0.55 ENST00000514944.5
ENST00000503591.1
ENST00000610292.4
ENST00000420246.6
ENST00000455263.6
ENST00000610538.4
ENST00000622645.4
ENST00000445888.6
ENST00000619485.4
ENST00000509690.5
ENST00000604348.5
ENST00000269305.9
ENST00000620739.4
TP53
tumor protein p53
chr10_+_122112957 0.55 ENST00000369001.5
TACC2
transforming acidic coiled-coil containing protein 2
chr11_+_706222 0.55 ENST00000318562.13
ENST00000533500.5
EPS8L2
EPS8 like 2
chr4_-_36244438 0.55 ENST00000303965.9
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr17_-_49210567 0.54 ENST00000507680.6
GNGT2
G protein subunit gamma transducin 2
chr16_+_89921851 0.53 ENST00000554444.5
ENST00000556565.5
TUBB3
tubulin beta 3 class III
chrX_-_49080066 0.53 ENST00000634944.1
ENST00000423215.3
ENST00000465382.6
WDR45
WD repeat domain 45
chr21_-_42010327 0.53 ENST00000398505.7
ENST00000449949.5
ENST00000310826.10
ENST00000398499.5
ENST00000398497.2
ENST00000398511.3
ZBTB21
zinc finger and BTB domain containing 21
chr1_-_150236150 0.52 ENST00000629042.2
ANP32E
acidic nuclear phosphoprotein 32 family member E
chr15_-_22980334 0.52 ENST00000610365.4
ENST00000617928.5
ENST00000611832.4
CYFIP1
cytoplasmic FMR1 interacting protein 1
chr16_+_83953232 0.52 ENST00000565123.5
ENST00000393306.6
OSGIN1
oxidative stress induced growth inhibitor 1
chr3_+_48465811 0.52 ENST00000433541.1
ENST00000444177.1
TREX1
three prime repair exonuclease 1
chr17_+_49210699 0.52 ENST00000225941.6
ABI3
ABI family member 3
chrX_+_49171889 0.51 ENST00000376327.6
PLP2
proteolipid protein 2
chrX_-_49043345 0.51 ENST00000315869.8
TFE3
transcription factor binding to IGHM enhancer 3
chr5_+_148202771 0.51 ENST00000514389.5
ENST00000621437.4
SPINK6
serine peptidase inhibitor Kazal type 6
chr5_+_150497772 0.51 ENST00000523767.5
NDST1
N-deacetylase and N-sulfotransferase 1
chr5_-_135578983 0.50 ENST00000512158.6
CXCL14
C-X-C motif chemokine ligand 14
chr7_+_150368189 0.49 ENST00000519397.1
ENST00000479668.5
REPIN1
replication initiator 1
chr17_-_29589536 0.48 ENST00000394869.7
GIT1
GIT ArfGAP 1
chr5_-_138575359 0.48 ENST00000297185.9
ENST00000678300.1
ENST00000677425.1
ENST00000677064.1
ENST00000507115.6
HSPA9
heat shock protein family A (Hsp70) member 9
chr1_-_109426410 0.48 ENST00000271308.9
PSMA5
proteasome 20S subunit alpha 5
chr15_-_55917080 0.47 ENST00000506154.1
NEDD4
NEDD4 E3 ubiquitin protein ligase
chr2_+_36696686 0.47 ENST00000379242.7
ENST00000389975.7
VIT
vitrin
chr4_-_39032922 0.47 ENST00000344606.6
TMEM156
transmembrane protein 156
chr12_-_70788914 0.47 ENST00000342084.8
PTPRR
protein tyrosine phosphatase receptor type R
chr19_+_49928702 0.47 ENST00000595125.5
ATF5
activating transcription factor 5

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 14.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
3.5 14.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
2.7 8.2 GO:0034148 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
2.0 6.1 GO:0006117 acetaldehyde metabolic process(GO:0006117)
1.5 8.7 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
1.0 3.1 GO:0046521 sphingoid catabolic process(GO:0046521)
1.0 3.0 GO:0042946 glucoside transport(GO:0042946)
1.0 5.0 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
1.0 3.8 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.8 11.0 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.8 5.0 GO:0007296 vitellogenesis(GO:0007296)
0.8 2.4 GO:0060720 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.8 2.4 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.7 8.0 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.7 0.7 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.7 4.0 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.6 1.8 GO:1990654 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.5 1.5 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.5 1.9 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.5 5.9 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.4 1.7 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.4 3.6 GO:0035897 proteolysis in other organism(GO:0035897)
0.4 3.9 GO:0001554 luteolysis(GO:0001554)
0.4 10.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.4 4.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.3 1.0 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.3 1.0 GO:0003192 mitral valve formation(GO:0003192)
0.3 0.9 GO:0035425 autocrine signaling(GO:0035425)
0.3 0.8 GO:0051821 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821)
0.3 9.1 GO:0030728 ovulation(GO:0030728)
0.3 0.6 GO:0051097 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.2 3.6 GO:0032329 serine transport(GO:0032329)
0.2 1.1 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.2 1.1 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.2 1.0 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.2 0.8 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.2 2.0 GO:0001866 NK T cell proliferation(GO:0001866)
0.2 3.0 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 0.6 GO:1902724 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.2 2.2 GO:0002934 desmosome organization(GO:0002934)
0.2 0.9 GO:1903238 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609) regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943) positive regulation of leukocyte tethering or rolling(GO:1903238)
0.2 0.5 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.2 0.7 GO:0044805 late nucleophagy(GO:0044805)
0.2 1.0 GO:0006041 glucosamine metabolic process(GO:0006041)
0.2 0.3 GO:1902623 negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.2 0.8 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.2 3.4 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.2 2.0 GO:0035092 sperm chromatin condensation(GO:0035092)
0.2 0.6 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.1 1.0 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.1 1.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 2.2 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.1 2.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 1.1 GO:0006741 NADP biosynthetic process(GO:0006741) regulation of NADP metabolic process(GO:1902031)
0.1 4.7 GO:0042730 fibrinolysis(GO:0042730)
0.1 0.4 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.1 0.4 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.1 0.4 GO:0060164 amygdala development(GO:0021764) regulation of timing of neuron differentiation(GO:0060164)
0.1 0.4 GO:1904692 positive regulation of type B pancreatic cell proliferation(GO:1904692)
0.1 2.0 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 0.4 GO:0002125 maternal aggressive behavior(GO:0002125) positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 1.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.4 GO:1990523 bone regeneration(GO:1990523)
0.1 0.3 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
0.1 1.7 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.1 0.7 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.1 5.2 GO:0043486 histone exchange(GO:0043486)
0.1 2.1 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.1 4.4 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.1 0.3 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 0.6 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.1 0.8 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.1 0.5 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.8 GO:0010265 SCF complex assembly(GO:0010265)
0.1 1.2 GO:0051451 myoblast migration(GO:0051451)
0.1 0.9 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1 0.2 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.1 0.5 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.4 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.7 GO:0006477 protein sulfation(GO:0006477)
0.1 3.7 GO:0034629 cellular protein complex localization(GO:0034629)
0.1 1.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.3 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 0.2 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.1 0.4 GO:0070317 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.3 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.1 1.4 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.1 3.5 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.3 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.1 0.6 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 0.2 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 0.4 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 1.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 3.6 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.2 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.6 GO:0014877 response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.5 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1 2.8 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.1 0.8 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 1.9 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 2.6 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.5 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.4 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.6 GO:0032740 positive regulation of interleukin-17 production(GO:0032740)
0.0 0.4 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 1.6 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:2001107 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.0 0.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.4 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.6 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.6 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.0 0.8 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 0.1 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.6 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.2 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.1 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.0 0.2 GO:1902748 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.3 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.4 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 1.8 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.1 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.0 0.4 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.8 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.9 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 2.6 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.1 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 1.0 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 1.7 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.3 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.2 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.4 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 1.1 GO:0002228 natural killer cell mediated immunity(GO:0002228)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.3 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.3 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.1 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 1.3 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.2 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.1 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.4 GO:0006882 cellular zinc ion homeostasis(GO:0006882)
0.0 0.6 GO:0006298 mismatch repair(GO:0006298)
0.0 0.2 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.2 GO:0030502 negative regulation of bone mineralization(GO:0030502) negative regulation of biomineral tissue development(GO:0070168)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.1 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
1.0 11.0 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
1.0 3.8 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.8 8.7 GO:0005638 lamin filament(GO:0005638)
0.8 9.1 GO:0043256 laminin complex(GO:0043256)
0.7 2.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.5 3.9 GO:0005827 polar microtubule(GO:0005827)
0.4 1.3 GO:0044753 amphisome(GO:0044753)
0.4 1.2 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.4 3.0 GO:0097451 glial limiting end-foot(GO:0097451)
0.3 1.0 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.3 12.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.3 3.0 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 5.2 GO:0000812 Swr1 complex(GO:0000812)
0.2 1.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 0.7 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.2 13.7 GO:0015030 Cajal body(GO:0015030)
0.1 0.8 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.4 GO:0035517 PR-DUB complex(GO:0035517)
0.1 0.9 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.4 GO:1990032 parallel fiber(GO:1990032)
0.1 1.3 GO:0031209 SCAR complex(GO:0031209)
0.1 1.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.8 GO:0072687 meiotic spindle(GO:0072687)
0.1 2.0 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 6.1 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 0.2 GO:0034515 proteasome storage granule(GO:0034515)
0.1 4.7 GO:0005771 multivesicular body(GO:0005771)
0.1 0.4 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 1.0 GO:0097512 cardiac myofibril(GO:0097512)
0.1 2.1 GO:0030057 desmosome(GO:0030057)
0.1 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.1 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 1.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.6 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.7 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 6.4 GO:0005604 basement membrane(GO:0005604)
0.0 0.7 GO:0042599 lamellar body(GO:0042599)
0.0 1.1 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.5 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 1.3 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.3 GO:0043219 lateral loop(GO:0043219)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0097470 ribbon synapse(GO:0097470)
0.0 1.6 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 16.0 GO:0031965 nuclear membrane(GO:0031965)
0.0 3.9 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.4 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.4 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.3 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.8 GO:0001533 cornified envelope(GO:0001533)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 2.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 7.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 1.0 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 5.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.7 GO:0002102 podosome(GO:0002102)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.6 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.8 GO:0005876 spindle microtubule(GO:0005876)
0.0 2.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.6 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.2 GO:0097433 dense body(GO:0097433)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 14.3 GO:0008859 exoribonuclease II activity(GO:0008859)
1.0 3.0 GO:0042947 glucoside transmembrane transporter activity(GO:0042947)
0.8 6.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.5 8.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.5 8.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.4 3.1 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.4 17.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.4 1.2 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.3 3.0 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 0.6 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.2 5.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.2 1.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.2 1.1 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.2 35.8 GO:0004896 cytokine receptor activity(GO:0004896)
0.2 0.8 GO:0043273 CTPase activity(GO:0043273)
0.2 3.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 1.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2 1.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.2 3.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.7 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 2.4 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 1.7 GO:0046870 cadmium ion binding(GO:0046870)
0.1 0.5 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 1.8 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.4 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955)
0.1 0.8 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.9 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.3 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.1 0.4 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1 0.3 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.3 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 1.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.7 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 3.0 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 3.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.3 GO:0005163 nerve growth factor receptor binding(GO:0005163)
0.1 1.8 GO:0030275 LRR domain binding(GO:0030275)
0.1 0.7 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.9 GO:0019956 chemokine binding(GO:0019956)
0.1 0.4 GO:0031893 vasopressin receptor binding(GO:0031893)
0.1 5.7 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.1 0.4 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.1 0.8 GO:0038132 neuregulin binding(GO:0038132)
0.1 2.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 5.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 9.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 2.0 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.6 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.6 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 1.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.5 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 1.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.5 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 1.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 5.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 7.1 GO:0008201 heparin binding(GO:0008201)
0.0 0.7 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 1.2 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 2.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.8 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0098918 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 1.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.6 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.9 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.8 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.7 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 5.3 GO:0001047 core promoter binding(GO:0001047)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.0 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 6.1 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 9.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 9.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3 14.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.2 14.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 3.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 6.7 ST GAQ PATHWAY G alpha q Pathway
0.1 7.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 6.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 1.8 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 1.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 4.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 1.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 2.2 PID IL1 PATHWAY IL1-mediated signaling events
0.1 0.6 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 1.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 2.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.3 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 4.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 15.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.6 PID AURORA A PATHWAY Aurora A signaling
0.0 0.8 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.3 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 6.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 8.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.1 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.3 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 1.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.4 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.5 PID RHOA PATHWAY RhoA signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.6 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.6 8.4 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.5 11.0 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.3 7.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 14.1 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.2 5.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 3.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 0.6 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.2 7.7 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.2 2.9 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.1 8.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 14.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 3.2 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 1.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 11.5 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 3.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 3.1 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 2.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 2.8 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 4.6 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 1.0 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 3.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.0 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 3.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.4 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 0.4 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 1.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 1.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.9 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.9 REACTOME INTERFERON SIGNALING Genes involved in Interferon Signaling
0.0 0.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates