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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for FOXA1

Z-value: 0.70

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Transcription factors associated with FOXA1

Gene Symbol Gene ID Gene Info
ENSG00000129514.8 FOXA1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXA1hg38_v1_chr14_-_37595224_375952810.125.7e-01Click!

Activity profile of FOXA1 motif

Sorted Z-values of FOXA1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXA1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr12_+_77830886 2.71 ENST00000397909.7
ENST00000549464.5
neuron navigator 3
chr2_+_149330506 2.06 ENST00000334166.9
LY6/PLAUR domain containing 6
chr5_+_136058849 2.03 ENST00000508076.5
transforming growth factor beta induced
chr22_+_20774092 1.57 ENST00000215727.10
serpin family D member 1
chr19_+_18386150 1.55 ENST00000252809.3
growth differentiation factor 15
chr6_-_31582415 1.53 ENST00000429299.3
ENST00000446745.2
lymphotoxin beta
chr17_+_76376581 1.49 ENST00000591651.5
ENST00000545180.5
sphingosine kinase 1
chr1_-_120100688 1.33 ENST00000652264.1
notch receptor 2
chr1_-_201127184 1.12 ENST00000449188.3
achaete-scute family bHLH transcription factor 5
chr10_+_89332484 1.07 ENST00000371811.4
ENST00000680037.1
ENST00000679583.1
ENST00000679897.1
interferon induced protein with tetratricopeptide repeats 3
chr10_+_113709261 1.07 ENST00000672138.1
ENST00000452490.3
caspase 7
chr5_+_150601060 1.05 ENST00000394243.5
synaptopodin
chr1_-_111200633 0.98 ENST00000357640.9
DENN domain containing 2D
chr3_-_146161167 0.97 ENST00000360060.7
ENST00000282903.10
procollagen-lysine,2-oxoglutarate 5-dioxygenase 2
chr8_+_119067239 0.97 ENST00000332843.3
collectin subfamily member 10
chr2_-_144431001 0.95 ENST00000636413.1
zinc finger E-box binding homeobox 2
chr8_+_32647080 0.94 ENST00000520502.7
ENST00000523041.2
ENST00000650819.1
neuregulin 1
chr6_+_36676489 0.90 ENST00000448526.6
cyclin dependent kinase inhibitor 1A
chr1_+_205256189 0.88 ENST00000329800.7
transmembrane and coiled-coil domain family 2
chr2_-_144516397 0.87 ENST00000638128.1
zinc finger E-box binding homeobox 2
chr2_-_144430934 0.85 ENST00000638087.1
ENST00000638007.1
zinc finger E-box binding homeobox 2
chr4_+_54229261 0.84 ENST00000508170.5
ENST00000512143.1
ENST00000257290.10
platelet derived growth factor receptor alpha
chr2_-_144516154 0.83 ENST00000637304.1
zinc finger E-box binding homeobox 2
chr11_-_9265302 0.82 ENST00000328194.8
DENN domain containing 5A
chr15_-_55249029 0.79 ENST00000566877.5
RAB27A, member RAS oncogene family
chr15_+_71096941 0.76 ENST00000355327.7
thrombospondin type 1 domain containing 4
chr18_+_3449413 0.75 ENST00000549253.5
TGFB induced factor homeobox 1
chr6_+_116399395 0.74 ENST00000644499.1
novel protein
chr6_-_87095059 0.73 ENST00000369582.6
ENST00000610310.3
ENST00000630630.2
ENST00000627148.3
ENST00000625577.1
glycoprotein hormones, alpha polypeptide
chr22_-_17219424 0.72 ENST00000649540.1
ENST00000399837.8
ENST00000543038.1
adenosine deaminase 2
chr3_-_71583713 0.69 ENST00000649528.3
ENST00000471386.3
ENST00000493089.7
forkhead box P1
chr14_+_104801082 0.67 ENST00000342537.8
zinc finger and BTB domain containing 42
chr22_-_17219571 0.66 ENST00000610390.4
adenosine deaminase 2
chr6_+_54018992 0.64 ENST00000509997.5
muscular LMNA interacting protein
chr8_+_125430333 0.61 ENST00000311922.4
tribbles pseudokinase 1
chr3_+_148730100 0.61 ENST00000474935.5
ENST00000475347.5
ENST00000461609.1
angiotensin II receptor type 1
chr15_+_60004305 0.61 ENST00000396057.6
forkhead box B1
chr21_-_14658812 0.60 ENST00000647101.1
SAM domain, SH3 domain and nuclear localization signals 1
chr5_+_162067764 0.57 ENST00000639213.2
ENST00000414552.6
gamma-aminobutyric acid type A receptor subunit gamma2
chr6_+_37929959 0.57 ENST00000373389.5
zinc finger AN1-type containing 3
chr5_+_98769273 0.56 ENST00000308234.11
repulsive guidance molecule BMP co-receptor b
chr5_+_162067500 0.56 ENST00000639384.1
ENST00000640985.1
ENST00000638772.1
gamma-aminobutyric acid type A receptor subunit gamma2
chr5_+_162067858 0.55 ENST00000361925.9
gamma-aminobutyric acid type A receptor subunit gamma2
chr6_-_89217339 0.54 ENST00000454853.7
gamma-aminobutyric acid type A receptor subunit rho1
chr11_-_108593738 0.52 ENST00000525344.5
ENST00000265843.9
exophilin 5
chr6_+_54018910 0.52 ENST00000514921.5
ENST00000274897.9
ENST00000370877.6
muscular LMNA interacting protein
chr8_+_32646838 0.52 ENST00000651333.1
ENST00000652592.1
neuregulin 1
chr5_+_162067458 0.50 ENST00000639975.1
ENST00000639111.2
ENST00000639683.1
gamma-aminobutyric acid type A receptor subunit gamma2
chr5_+_162068031 0.49 ENST00000356592.8
gamma-aminobutyric acid type A receptor subunit gamma2
chr3_+_52211442 0.49 ENST00000459884.1
5'-aminolevulinate synthase 1
chr11_+_107928394 0.47 ENST00000320578.3
RAB39A, member RAS oncogene family
chr7_-_32299287 0.47 ENST00000396193.5
phosphodiesterase 1C
chr11_+_35662739 0.45 ENST00000299413.7
tripartite motif containing 44
chr16_-_87936529 0.43 ENST00000649794.3
ENST00000649158.1
ENST00000648177.1
carbonic anhydrase 5A
chr6_-_43629222 0.43 ENST00000307126.10
GTP binding protein 2
chr17_+_9021501 0.43 ENST00000173229.7
netrin 1
chr4_+_164754116 0.43 ENST00000507311.1
small integral membrane protein 31
chr2_+_202073282 0.43 ENST00000459709.5
KIAA2012
chr7_+_114414809 0.43 ENST00000350908.9
forkhead box P2
chr14_-_56805648 0.42 ENST00000554788.5
ENST00000554845.1
ENST00000408990.8
orthodenticle homeobox 2
chr2_+_202073249 0.41 ENST00000498697.3
KIAA2012
chr1_-_248748327 0.41 ENST00000651827.1
novel protein
chr2_-_68952880 0.41 ENST00000481498.1
ENST00000328895.9
gastrokine 2
chr1_-_116667668 0.40 ENST00000369486.8
ENST00000369483.5
immunoglobulin superfamily member 3
chr3_+_189631373 0.40 ENST00000264731.8
ENST00000418709.6
ENST00000320472.9
ENST00000392460.7
ENST00000440651.6
tumor protein p63
chr11_-_116792386 0.38 ENST00000433069.2
ENST00000542499.5
apolipoprotein A5
chr9_-_86947496 0.38 ENST00000298743.9
growth arrest specific 1
chr5_-_41213505 0.37 ENST00000337836.10
ENST00000433294.1
complement C6
chr1_+_86468902 0.37 ENST00000394711.2
chloride channel accessory 1
chr12_-_52434363 0.36 ENST00000252245.6
keratin 75
chr2_-_218985176 0.36 ENST00000295727.2
FEV transcription factor, ETS family member
chr13_+_50015438 0.35 ENST00000312942.2
potassium channel regulator
chr13_+_50015254 0.35 ENST00000360473.8
potassium channel regulator
chr17_-_28368012 0.35 ENST00000555059.2
novel protein, readthrough between VTN and SEBOX
chr4_+_85475131 0.35 ENST00000395184.6
Rho GTPase activating protein 24
chr16_-_48610150 0.35 ENST00000262384.4
NEDD4 binding protein 1
chr1_-_56966006 0.34 ENST00000371237.9
complement C8 beta chain
chr21_-_26843012 0.34 ENST00000517777.6
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr2_+_168901290 0.34 ENST00000429379.2
ENST00000375363.8
ENST00000421979.1
glucose-6-phosphatase catalytic subunit 2
chrX_+_151176582 0.34 ENST00000218316.4
G protein-coupled receptor 50
chr3_-_186362223 0.34 ENST00000265022.8
diacylglycerol kinase gamma
chr17_-_41528293 0.34 ENST00000455635.1
ENST00000361566.7
keratin 19
chr7_-_81770122 0.33 ENST00000423064.7
hepatocyte growth factor
chr4_-_163613505 0.33 ENST00000339875.9
membrane associated ring-CH-type finger 1
chr1_-_206921867 0.33 ENST00000628511.2
ENST00000367091.8
Fc fragment of IgM receptor
chr14_-_21025490 0.33 ENST00000553442.5
ENST00000555869.5
ENST00000556457.5
ENST00000397844.6
ENST00000554415.5
ENST00000556974.5
ENST00000554419.5
ENST00000298687.9
ENST00000397858.5
ENST00000360463.7
ENST00000350792.7
ENST00000397847.6
NDRG family member 2
chr1_-_206921987 0.32 ENST00000530505.1
ENST00000442471.4
Fc fragment of IgM receptor
chr6_-_160664270 0.32 ENST00000316300.10
lipoprotein(a)
chr7_+_28412511 0.32 ENST00000357727.7
cAMP responsive element binding protein 5
chr17_-_50468871 0.32 ENST00000508540.6
ENST00000258969.4
chondroadherin
chrX_+_136532205 0.31 ENST00000370634.8
vestigial like family member 1
chr1_-_177970213 0.31 ENST00000464631.6
SEC16 homolog B, endoplasmic reticulum export factor
chr2_-_21044063 0.31 ENST00000233242.5
apolipoprotein B
chr16_+_7332839 0.31 ENST00000355637.9
RNA binding fox-1 homolog 1
chr11_+_13962676 0.31 ENST00000576479.4
spondin 1
chr3_-_190449782 0.30 ENST00000354905.3
transmembrane protein 207
chr21_-_26843063 0.30 ENST00000678221.1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr5_+_96663010 0.30 ENST00000506811.5
ENST00000514055.5
ENST00000508608.6
calpastatin
chr10_+_122163590 0.29 ENST00000368999.5
transforming acidic coiled-coil containing protein 2
chrX_+_22032301 0.29 ENST00000379374.5
phosphate regulating endopeptidase homolog X-linked
chr7_+_134891566 0.29 ENST00000424922.5
ENST00000495522.1
caldesmon 1
chr6_-_39322968 0.29 ENST00000507712.5
potassium two pore domain channel subfamily K member 16
chr20_-_7940444 0.28 ENST00000378789.4
hydroxyacid oxidase 1
chr3_-_71583683 0.28 ENST00000649631.1
ENST00000648718.1
forkhead box P1
chr19_-_48615050 0.28 ENST00000263266.4
family with sequence similarity 83 member E
chr22_-_40533808 0.28 ENST00000422851.1
ENST00000651694.1
ENST00000652095.2
myocardin related transcription factor A
chr4_+_164754045 0.28 ENST00000515485.5
small integral membrane protein 31
chr16_+_7332744 0.28 ENST00000436368.6
ENST00000311745.9
ENST00000340209.8
ENST00000620507.4
RNA binding fox-1 homolog 1
chr17_-_47957824 0.27 ENST00000300557.3
proline rich 15 like
chr5_-_142686079 0.27 ENST00000337706.7
fibroblast growth factor 1
chr12_+_120978686 0.26 ENST00000541395.5
ENST00000544413.2
HNF1 homeobox A
chr1_-_56966133 0.26 ENST00000535057.5
ENST00000543257.5
complement C8 beta chain
chr10_-_31031911 0.26 ENST00000375311.1
ENST00000413025.5
ENST00000436087.6
ENST00000452305.5
ENST00000442986.5
zinc finger protein 438
chr19_+_42302098 0.26 ENST00000598490.1
ENST00000341747.8
proline rich 19
chr10_+_122163672 0.26 ENST00000369004.7
ENST00000260733.7
transforming acidic coiled-coil containing protein 2
chr20_+_45791930 0.26 ENST00000372622.8
deoxynucleotidyltransferase terminal interacting protein 1
chr10_+_49299159 0.26 ENST00000374144.8
chromosome 10 open reading frame 71
chr12_+_10505890 0.26 ENST00000538173.1
eukaryotic translation initiation factor 2 subunit gamma B
chr11_+_31812307 0.25 ENST00000643436.1
ENST00000646959.1
ENST00000645942.1
ENST00000530348.5
PAX6 upstream antisense RNA
novel protein
chr5_-_136365476 0.25 ENST00000378459.7
ENST00000502753.4
ENST00000513104.6
ENST00000352189.8
transient receptor potential cation channel subfamily C member 7
chr7_+_130266847 0.24 ENST00000222481.9
carboxypeptidase A2
chr21_-_42350987 0.24 ENST00000291526.5
trefoil factor 2
chr1_+_204870831 0.24 ENST00000404076.5
ENST00000539706.6
neurofascin
chr3_+_108602776 0.24 ENST00000497905.5
ENST00000463306.1
DAZ interacting zinc finger protein 3
chrX_+_1268807 0.24 ENST00000381524.8
ENST00000381529.9
ENST00000412290.6
colony stimulating factor 2 receptor subunit alpha
chr13_-_46142834 0.24 ENST00000674665.1
lymphocyte cytosolic protein 1
chr14_-_31457495 0.24 ENST00000310850.9
D-aminoacyl-tRNA deacylase 2
chr6_+_52420992 0.24 ENST00000636954.1
ENST00000636566.1
ENST00000638075.1
EF-hand domain containing 1
chr3_+_160677152 0.23 ENST00000320767.4
ADP ribosylation factor like GTPase 14
chr6_+_10528326 0.23 ENST00000379597.7
glucosaminyl (N-acetyl) transferase 2 (I blood group)
chr19_+_38390055 0.23 ENST00000587947.5
ENST00000338502.8
sprouty related EVH1 domain containing 3
chr9_-_14722725 0.22 ENST00000380911.4
cerberus 1, DAN family BMP antagonist
chr12_+_120978537 0.22 ENST00000257555.11
ENST00000400024.6
HNF1 homeobox A
chr11_+_66258467 0.22 ENST00000394066.6
kinesin light chain 2
chr4_+_67558719 0.22 ENST00000265404.7
ENST00000396225.1
signal transducing adaptor family member 1
chr9_-_120477354 0.21 ENST00000416449.5
CDK5 regulatory subunit associated protein 2
chr12_-_21334858 0.21 ENST00000445053.1
ENST00000458504.5
ENST00000422327.5
ENST00000683939.1
solute carrier organic anion transporter family member 1A2
chr7_-_100100716 0.21 ENST00000354230.7
ENST00000425308.5
minichromosome maintenance complex component 7
chr4_+_164877164 0.21 ENST00000507152.6
ENST00000515275.1
apelin receptor early endogenous ligand
chr14_+_36657560 0.21 ENST00000402703.6
paired box 9
chr10_+_18400562 0.21 ENST00000377315.5
ENST00000650685.1
calcium voltage-gated channel auxiliary subunit beta 2
chr10_+_102776237 0.21 ENST00000369889.5
WW domain binding protein 1 like
chr2_+_151409878 0.20 ENST00000453091.6
ENST00000428287.6
ENST00000444746.7
ENST00000243326.9
ENST00000414861.6
replication timing regulatory factor 1
chr19_-_45406327 0.20 ENST00000593226.5
ENST00000418234.6
protein phosphatase 1 regulatory subunit 13 like
chr15_+_84237586 0.20 ENST00000512109.1
golgin A6 family like 4
chr11_-_107712049 0.19 ENST00000305991.3
sarcolipin
chr1_-_246566238 0.19 ENST00000366514.5
transcription factor B2, mitochondrial
chr2_+_151410090 0.19 ENST00000430328.6
replication timing regulatory factor 1
chr10_+_116590956 0.19 ENST00000358834.9
ENST00000528052.5
pancreatic lipase related protein 1
chr13_-_85799400 0.19 ENST00000647374.2
SLIT and NTRK like family member 6
chr2_-_49154433 0.18 ENST00000454032.5
ENST00000304421.8
follicle stimulating hormone receptor
chr14_-_31457417 0.18 ENST00000356180.4
D-aminoacyl-tRNA deacylase 2
chr11_+_119334511 0.18 ENST00000311413.5
ring finger protein 26
chr6_-_132659178 0.18 ENST00000275216.3
trace amine associated receptor 1
chr7_+_134745460 0.18 ENST00000436461.6
caldesmon 1
chr5_-_149379286 0.18 ENST00000261796.4
interleukin 17B
chr6_-_89315291 0.18 ENST00000402938.4
gamma-aminobutyric acid type A receptor subunit rho2
chr2_-_49154507 0.17 ENST00000406846.7
follicle stimulating hormone receptor
chr18_+_3449620 0.17 ENST00000405385.7
TGFB induced factor homeobox 1
chr2_+_17541157 0.17 ENST00000406397.1
visinin like 1
chr14_-_37595224 0.16 ENST00000250448.5
forkhead box A1
chr11_+_121102666 0.16 ENST00000264037.2
tectorin alpha
chrX_-_48958348 0.16 ENST00000428668.2
OTU deubiquitinase 5
chr14_+_36661852 0.16 ENST00000361487.7
paired box 9
chr1_-_244860376 0.16 ENST00000638716.1
heterogeneous nuclear ribonucleoprotein U
chr14_+_23185316 0.16 ENST00000399910.5
ENST00000492621.5
ring finger protein 212B
chr6_-_107824294 0.16 ENST00000369020.8
ENST00000369022.6
Scm polycomb group protein like 4
chr14_-_99271485 0.15 ENST00000345514.2
ENST00000443726.2
BAF chromatin remodeling complex subunit BCL11B
chr1_-_26913964 0.15 ENST00000254227.4
nuclear receptor subfamily 0 group B member 2
chr2_-_213151590 0.15 ENST00000374319.8
ENST00000457361.5
ENST00000451136.6
ENST00000434687.6
IKAROS family zinc finger 2
chr14_-_99272184 0.15 ENST00000357195.8
BAF chromatin remodeling complex subunit BCL11B
chr5_+_40841308 0.15 ENST00000381677.4
ENST00000254691.10
caspase recruitment domain family member 6
chr3_+_98353854 0.15 ENST00000354924.2
olfactory receptor family 5 subfamily K member 4
chr3_+_186996444 0.14 ENST00000676633.1
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr1_+_50105666 0.14 ENST00000651347.1
ELAV like RNA binding protein 4
chr7_-_107803215 0.14 ENST00000340010.10
ENST00000453332.1
solute carrier family 26 member 3
chr8_+_86866415 0.14 ENST00000518476.6
cyclic nucleotide binding domain containing 1
chr14_+_22829879 0.14 ENST00000355151.9
ENST00000397496.7
ENST00000555345.5
ENST00000432849.7
ENST00000553711.5
ENST00000556465.5
ENST00000397505.2
ENST00000557221.1
ENST00000556840.5
ENST00000555536.1
mitochondrial ribosomal protein L52
chr1_-_178871022 0.14 ENST00000367629.1
angiopoietin like 1
chr1_-_11047225 0.14 ENST00000400898.3
ENST00000400897.8
mannan binding lectin serine peptidase 2
chr9_+_137230757 0.14 ENST00000673865.1
ENST00000538474.5
ENST00000673835.1
ENST00000673953.1
ENST00000361134.2
solute carrier family 34 member 3
chr5_-_138338325 0.14 ENST00000510119.1
ENST00000513970.5
cell division cycle 25C
chr1_-_152360004 0.14 ENST00000388718.5
filaggrin family member 2
chrX_-_15384402 0.13 ENST00000297904.4
vascular endothelial growth factor D
chr21_-_42315336 0.13 ENST00000398431.2
ENST00000518498.3
trefoil factor 3
chr7_+_112423137 0.13 ENST00000005558.8
ENST00000621379.4
interferon related developmental regulator 1
chr10_-_79949098 0.13 ENST00000372292.8
surfactant protein D
chr1_+_74235377 0.13 ENST00000326637.8
TNNI3 interacting kinase
chrX_-_15600953 0.13 ENST00000679212.1
ENST00000679278.1
ENST00000678046.1
ENST00000252519.8
angiotensin I converting enzyme 2
chr1_+_43389874 0.13 ENST00000372450.8
SZT2 subunit of KICSTOR complex
chr2_+_172085499 0.12 ENST00000361725.5
ENST00000341900.6
distal-less homeobox 1
chr22_-_45008938 0.12 ENST00000420689.1
ENST00000403565.5
ENST00000396103.7
PHD finger protein 21B
chr5_+_96662969 0.11 ENST00000514845.5
ENST00000675663.1
calpastatin
chr1_-_43389768 0.11 ENST00000372455.4
ENST00000372457.9
ENST00000290663.10
mediator complex subunit 8
chr14_-_69797232 0.11 ENST00000216540.5
solute carrier family 10 member 1
chr20_-_57266606 0.11 ENST00000450594.6
ENST00000395863.8
bone morphogenetic protein 7
chr5_+_96936071 0.11 ENST00000231368.10
leucyl and cystinyl aminopeptidase
chr19_-_48390847 0.11 ENST00000597017.5
KDEL endoplasmic reticulum protein retention receptor 1
chr10_-_79560386 0.11 ENST00000372327.9
ENST00000417041.1
ENST00000640627.1
ENST00000372325.7
surfactant protein A2
chr1_-_94925759 0.11 ENST00000415017.1
ENST00000545882.5
calponin 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0046521 sphingoid catabolic process(GO:0046521)
0.5 4.1 GO:0061373 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373)
0.3 0.8 GO:0072276 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.3 1.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.3 1.6 GO:0008218 bioluminescence(GO:0008218)
0.2 1.0 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.2 0.6 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.2 1.4 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.2 0.5 GO:0021757 caudate nucleus development(GO:0021757) putamen development(GO:0021758)
0.2 1.5 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.2 0.5 GO:0035565 regulation of pronephros size(GO:0035565)
0.2 0.6 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 1.1 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 0.8 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.4 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.1 1.5 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.3 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.1 0.3 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.1 0.4 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.9 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.1 2.7 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.4 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.1 0.4 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.1 1.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.4 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 0.3 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 0.2 GO:1903973 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.1 0.2 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.1 1.1 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 1.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.1 GO:0007518 myoblast fate determination(GO:0007518)
0.1 0.2 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.1 0.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 1.0 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.2 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.4 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.2 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.0 1.6 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.4 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.4 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.2 GO:1905069 neural fold elevation formation(GO:0021502) nephrogenic mesenchyme morphogenesis(GO:0072134) allantois development(GO:1905069)
0.0 0.3 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.2 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0021893 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.7 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.3 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.6 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 2.1 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.5 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.5 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.4 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0035638 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.4 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.5 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.2 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.4 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.1 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897) secretory granule localization(GO:0032252)
0.0 0.4 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.2 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:1903598 positive regulation of gap junction assembly(GO:1903598)
0.0 0.1 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.3 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.3 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.1 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.3 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.4 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.8 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.2 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.7 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.9 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.1 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.0 0.2 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.1 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.2 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.6 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.0 0.4 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0097444 spine apparatus(GO:0097444)
0.2 0.9 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 1.0 GO:0005579 membrane attack complex(GO:0005579)
0.1 3.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.2 GO:0016938 kinesin I complex(GO:0016938)
0.1 0.8 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.2 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.0 0.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 2.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.4 GO:0001940 female pronucleus(GO:0001939) male pronucleus(GO:0001940)
0.0 0.3 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.2 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.8 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.5 GO:0030478 actin cap(GO:0030478)
0.0 1.5 GO:0030673 axolemma(GO:0030673)
0.0 1.0 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.8 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 3.1 GO:0005604 basement membrane(GO:0005604)
0.0 0.4 GO:0042627 chylomicron(GO:0042627)
0.0 0.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 1.4 GO:0005902 microvillus(GO:0005902)
0.0 1.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.3 0.8 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.2 1.0 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.2 1.5 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.2 0.6 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.2 0.9 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 2.7 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 1.3 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.1 1.4 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.4 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.1 0.3 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.4 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 0.7 GO:0035473 lipase binding(GO:0035473)
0.1 0.5 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.3 GO:0052852 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.1 1.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 3.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.0 GO:0005537 mannose binding(GO:0005537)
0.0 0.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.1 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 1.1 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0001855 complement component C4b binding(GO:0001855)
0.0 0.6 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.9 GO:0070410 co-SMAD binding(GO:0070410)
0.0 1.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.8 GO:0031489 myosin V binding(GO:0031489)
0.0 1.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 1.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.7 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0036122 BMP binding(GO:0036122)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 1.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 1.5 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.5 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.3 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.0 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.0 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 3.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 2.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.8 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.0 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.3 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.6 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 1.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 3.4 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 1.0 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 0.7 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 2.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.9 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 1.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling