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Inflammatory response time course, HUVEC (Wada, 2009)
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Results for FOXD1_FOXO1_FOXO6_FOXG1_FOXP1
Z-value: 1.22
Motif logo
Transcription factors associated with FOXD1_FOXO1_FOXO6_FOXG1_FOXP1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
FOXD1
|
ENSG00000251493.5 | FOXD1 |
|
FOXO1
|
ENSG00000150907.10 | FOXO1 |
|
FOXO6
|
ENSG00000204060.7 | FOXO6 |
|
FOXG1
|
ENSG00000176165.12 | FOXG1 |
|
FOXP1
|
ENSG00000114861.23 | FOXP1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| FOXP1 | hg38_v1_chr3_-_71130892_71130959 | -0.56 | 3.3e-03 | Click! |
| FOXG1 | hg38_v1_chr14_+_28766755_28766802 | -0.47 | 1.9e-02 | Click! |
| FOXO1 | hg38_v1_chr13_-_40666600_40666650 | 0.44 | 3.0e-02 | Click! |
| FOXD1 | hg38_v1_chr5_-_73448769_73448784 | -0.16 | 4.5e-01 | Click! |
Activity profile of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1 motif
Sorted Z-values of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.1 | 14.6 | GO:0097338 | response to clozapine(GO:0097338) |
| 1.9 | 7.7 | GO:0042091 | interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074) |
| 1.7 | 5.1 | GO:0046725 | negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) |
| 1.5 | 7.3 | GO:0072674 | multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675) |
| 0.9 | 2.8 | GO:0021986 | epithalamus development(GO:0021538) habenula development(GO:0021986) |
| 0.8 | 5.9 | GO:0000821 | regulation of arginine metabolic process(GO:0000821) |
| 0.7 | 2.8 | GO:1903758 | regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 0.7 | 3.5 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 0.7 | 2.0 | GO:0001869 | regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869) |
| 0.6 | 2.6 | GO:1904428 | negative regulation of tubulin deacetylation(GO:1904428) |
| 0.6 | 4.5 | GO:0071477 | hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) |
| 0.6 | 3.1 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
| 0.6 | 1.8 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
| 0.6 | 8.5 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.5 | 4.1 | GO:0003185 | primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) |
| 0.5 | 2.0 | GO:0009956 | radial pattern formation(GO:0009956) |
| 0.5 | 1.4 | GO:0061114 | hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979) |
| 0.5 | 5.1 | GO:0033227 | dsRNA transport(GO:0033227) |
| 0.4 | 1.3 | GO:0015917 | aminophospholipid transport(GO:0015917) |
| 0.4 | 4.1 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.4 | 1.2 | GO:0060164 | regulation of timing of neuron differentiation(GO:0060164) |
| 0.4 | 2.3 | GO:2000504 | endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504) |
| 0.4 | 2.2 | GO:0008204 | ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204) |
| 0.4 | 4.0 | GO:0006552 | leucine catabolic process(GO:0006552) |
| 0.3 | 5.9 | GO:2000774 | positive regulation of cellular senescence(GO:2000774) |
| 0.3 | 4.7 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 0.3 | 2.7 | GO:0048014 | Tie signaling pathway(GO:0048014) |
| 0.3 | 3.9 | GO:0098734 | macromolecule depalmitoylation(GO:0098734) |
| 0.3 | 0.9 | GO:0090285 | negative regulation of protein glycosylation in Golgi(GO:0090285) |
| 0.3 | 0.9 | GO:0031550 | positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550) |
| 0.3 | 1.7 | GO:0046340 | diacylglycerol catabolic process(GO:0046340) |
| 0.3 | 4.0 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
| 0.3 | 1.4 | GO:0093001 | glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001) |
| 0.3 | 5.4 | GO:0018214 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
| 0.3 | 0.8 | GO:0060139 | positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263) |
| 0.3 | 1.5 | GO:0060355 | positive regulation of cell adhesion molecule production(GO:0060355) |
| 0.3 | 1.8 | GO:0030421 | defecation(GO:0030421) |
| 0.2 | 0.7 | GO:0036071 | N-glycan fucosylation(GO:0036071) |
| 0.2 | 0.7 | GO:0035026 | leading edge cell differentiation(GO:0035026) |
| 0.2 | 1.4 | GO:0097167 | circadian regulation of translation(GO:0097167) |
| 0.2 | 1.2 | GO:2000690 | negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691) |
| 0.2 | 0.7 | GO:1900169 | regulation of glucocorticoid mediated signaling pathway(GO:1900169) |
| 0.2 | 1.7 | GO:0035290 | trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) |
| 0.2 | 0.9 | GO:1902617 | response to fluoride(GO:1902617) |
| 0.2 | 3.3 | GO:0015074 | DNA integration(GO:0015074) |
| 0.2 | 0.7 | GO:1990926 | short-term synaptic potentiation(GO:1990926) |
| 0.2 | 0.7 | GO:0009597 | detection of virus(GO:0009597) |
| 0.2 | 4.9 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
| 0.2 | 1.3 | GO:0002282 | microglial cell activation involved in immune response(GO:0002282) macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) |
| 0.2 | 1.5 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
| 0.2 | 2.1 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 0.2 | 0.8 | GO:0001080 | nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of nitrogen utilization(GO:0006808) nitrogen utilization(GO:0019740) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250) |
| 0.2 | 0.6 | GO:0071603 | endothelial cell-cell adhesion(GO:0071603) |
| 0.2 | 0.8 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
| 0.2 | 0.6 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
| 0.2 | 0.6 | GO:1904017 | cellular response to Thyroglobulin triiodothyronine(GO:1904017) |
| 0.2 | 1.8 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.2 | 2.0 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
| 0.2 | 2.1 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) |
| 0.2 | 2.8 | GO:0021527 | spinal cord association neuron differentiation(GO:0021527) |
| 0.2 | 5.0 | GO:0072189 | ureter development(GO:0072189) |
| 0.2 | 0.8 | GO:1901350 | cell-cell signaling involved in cell-cell junction organization(GO:1901350) |
| 0.2 | 0.8 | GO:0051389 | inactivation of MAPKK activity(GO:0051389) |
| 0.2 | 0.5 | GO:0072709 | cellular response to sorbitol(GO:0072709) |
| 0.1 | 0.3 | GO:2000078 | positive regulation of type B pancreatic cell development(GO:2000078) |
| 0.1 | 2.2 | GO:0035372 | protein localization to microtubule(GO:0035372) |
| 0.1 | 2.2 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.1 | 1.6 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.1 | 0.6 | GO:1990737 | regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) response to manganese-induced endoplasmic reticulum stress(GO:1990737) |
| 0.1 | 1.8 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 0.1 | 0.4 | GO:1903674 | regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676) |
| 0.1 | 1.9 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 0.1 | 6.3 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 0.1 | 1.6 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
| 0.1 | 0.9 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
| 0.1 | 3.4 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.1 | 0.4 | GO:0006533 | aspartate catabolic process(GO:0006533) |
| 0.1 | 0.4 | GO:0006864 | pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519) |
| 0.1 | 0.5 | GO:1990535 | neuron projection maintenance(GO:1990535) |
| 0.1 | 0.5 | GO:0032072 | plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) |
| 0.1 | 3.9 | GO:0060065 | uterus development(GO:0060065) |
| 0.1 | 0.5 | GO:0055011 | atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014) |
| 0.1 | 1.8 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
| 0.1 | 0.5 | GO:0090095 | metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096) |
| 0.1 | 0.5 | GO:0002032 | desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032) |
| 0.1 | 0.2 | GO:1904844 | response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845) |
| 0.1 | 4.5 | GO:0071425 | hematopoietic stem cell proliferation(GO:0071425) |
| 0.1 | 1.4 | GO:0014877 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.1 | 10.2 | GO:0032981 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.1 | 2.6 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.1 | 2.6 | GO:0046069 | cGMP catabolic process(GO:0046069) |
| 0.1 | 0.7 | GO:0051945 | negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470) |
| 0.1 | 4.3 | GO:0061049 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.1 | 1.0 | GO:0031666 | positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666) |
| 0.1 | 0.6 | GO:0044860 | protein localization to plasma membrane raft(GO:0044860) |
| 0.1 | 1.2 | GO:0031087 | deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
| 0.1 | 12.7 | GO:0010324 | membrane invagination(GO:0010324) |
| 0.1 | 0.6 | GO:1903566 | positive regulation of protein localization to cilium(GO:1903566) |
| 0.1 | 4.8 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.1 | 0.3 | GO:0003245 | cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) |
| 0.1 | 0.9 | GO:0060125 | habituation(GO:0046959) negative regulation of growth hormone secretion(GO:0060125) |
| 0.1 | 0.8 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.1 | 4.4 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
| 0.1 | 0.4 | GO:0021569 | rhombomere 3 development(GO:0021569) |
| 0.1 | 0.3 | GO:1904479 | negative regulation of intestinal absorption(GO:1904479) |
| 0.1 | 6.3 | GO:0043268 | positive regulation of potassium ion transport(GO:0043268) |
| 0.1 | 1.1 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 0.1 | 0.3 | GO:0046603 | negative regulation of mitotic centrosome separation(GO:0046603) |
| 0.1 | 2.8 | GO:2000249 | regulation of actin cytoskeleton reorganization(GO:2000249) |
| 0.1 | 0.7 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.1 | 0.4 | GO:0090131 | mesenchyme migration(GO:0090131) |
| 0.1 | 8.9 | GO:1901222 | regulation of NIK/NF-kappaB signaling(GO:1901222) |
| 0.1 | 0.3 | GO:0018032 | protein amidation(GO:0018032) |
| 0.1 | 0.3 | GO:0051919 | positive regulation of fibrinolysis(GO:0051919) |
| 0.1 | 0.4 | GO:2000653 | regulation of genetic imprinting(GO:2000653) |
| 0.1 | 0.3 | GO:1904379 | protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379) |
| 0.1 | 0.4 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
| 0.1 | 0.6 | GO:0044211 | CTP salvage(GO:0044211) |
| 0.1 | 1.0 | GO:0045176 | apical protein localization(GO:0045176) |
| 0.1 | 7.4 | GO:0048208 | vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) |
| 0.1 | 1.2 | GO:2000807 | regulation of synaptic vesicle clustering(GO:2000807) |
| 0.1 | 1.0 | GO:0045023 | G0 to G1 transition(GO:0045023) |
| 0.1 | 0.1 | GO:0010726 | positive regulation of hydrogen peroxide metabolic process(GO:0010726) |
| 0.1 | 1.5 | GO:1904355 | positive regulation of telomere capping(GO:1904355) |
| 0.1 | 1.1 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.1 | 0.6 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
| 0.1 | 1.2 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 0.1 | 0.3 | GO:0051138 | positive regulation of NK T cell differentiation(GO:0051138) |
| 0.1 | 0.2 | GO:1902595 | regulation of DNA replication origin binding(GO:1902595) |
| 0.1 | 0.4 | GO:0048170 | positive regulation of long-term neuronal synaptic plasticity(GO:0048170) |
| 0.1 | 1.1 | GO:0006198 | cAMP catabolic process(GO:0006198) |
| 0.1 | 0.1 | GO:2000850 | negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850) |
| 0.1 | 0.3 | GO:1904219 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222) |
| 0.1 | 0.5 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.1 | 0.3 | GO:0001757 | somite specification(GO:0001757) |
| 0.1 | 0.3 | GO:0070427 | nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427) |
| 0.1 | 0.2 | GO:0007386 | compartment pattern specification(GO:0007386) |
| 0.1 | 1.2 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
| 0.1 | 17.3 | GO:0065004 | protein-DNA complex assembly(GO:0065004) |
| 0.1 | 0.2 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
| 0.1 | 0.8 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
| 0.1 | 0.4 | GO:0006196 | AMP catabolic process(GO:0006196) |
| 0.1 | 0.7 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
| 0.1 | 0.8 | GO:0045603 | positive regulation of endothelial cell differentiation(GO:0045603) |
| 0.1 | 0.2 | GO:0010159 | specification of organ position(GO:0010159) |
| 0.1 | 0.2 | GO:0061055 | myotome development(GO:0061055) |
| 0.1 | 0.6 | GO:0031507 | heterochromatin assembly(GO:0031507) |
| 0.1 | 1.5 | GO:0035162 | embryonic hemopoiesis(GO:0035162) |
| 0.1 | 0.8 | GO:0008090 | retrograde axonal transport(GO:0008090) |
| 0.1 | 0.4 | GO:0009624 | response to nematode(GO:0009624) |
| 0.1 | 0.5 | GO:0090178 | regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179) |
| 0.1 | 2.3 | GO:1900739 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
| 0.1 | 0.3 | GO:0001692 | histamine metabolic process(GO:0001692) |
| 0.1 | 0.5 | GO:0098909 | regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) |
| 0.1 | 0.6 | GO:0042998 | positive regulation of Golgi to plasma membrane protein transport(GO:0042998) |
| 0.1 | 0.2 | GO:0098957 | anterograde axonal transport of mitochondrion(GO:0098957) |
| 0.1 | 0.6 | GO:0050861 | positive regulation of B cell receptor signaling pathway(GO:0050861) |
| 0.1 | 1.5 | GO:0036152 | phosphatidylethanolamine acyl-chain remodeling(GO:0036152) |
| 0.1 | 1.3 | GO:2000811 | negative regulation of anoikis(GO:2000811) |
| 0.0 | 0.4 | GO:0003215 | cardiac right ventricle morphogenesis(GO:0003215) |
| 0.0 | 0.4 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.0 | 1.1 | GO:0010832 | negative regulation of myotube differentiation(GO:0010832) |
| 0.0 | 1.2 | GO:1901663 | ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
| 0.0 | 0.5 | GO:0033689 | negative regulation of osteoblast proliferation(GO:0033689) |
| 0.0 | 0.3 | GO:0045409 | metanephric part of ureteric bud development(GO:0035502) negative regulation of interleukin-6 biosynthetic process(GO:0045409) |
| 0.0 | 0.6 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.0 | 7.0 | GO:0006338 | chromatin remodeling(GO:0006338) |
| 0.0 | 0.2 | GO:0038016 | insulin receptor internalization(GO:0038016) |
| 0.0 | 0.2 | GO:0071386 | cellular response to corticosterone stimulus(GO:0071386) |
| 0.0 | 1.8 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
| 0.0 | 0.8 | GO:0034656 | nucleobase-containing small molecule catabolic process(GO:0034656) |
| 0.0 | 0.1 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
| 0.0 | 1.0 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 0.0 | 0.2 | GO:0030070 | insulin processing(GO:0030070) |
| 0.0 | 0.7 | GO:1902187 | negative regulation of viral release from host cell(GO:1902187) |
| 0.0 | 0.1 | GO:0021759 | globus pallidus development(GO:0021759) |
| 0.0 | 0.5 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
| 0.0 | 0.2 | GO:0044334 | canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) |
| 0.0 | 0.2 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 0.0 | 0.1 | GO:0032455 | nerve growth factor processing(GO:0032455) |
| 0.0 | 0.9 | GO:0042994 | cytoplasmic sequestering of transcription factor(GO:0042994) |
| 0.0 | 0.2 | GO:0006651 | diacylglycerol biosynthetic process(GO:0006651) |
| 0.0 | 0.9 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.0 | 2.2 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
| 0.0 | 0.2 | GO:0090308 | regulation of methylation-dependent chromatin silencing(GO:0090308) |
| 0.0 | 0.2 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.0 | 0.3 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
| 0.0 | 0.1 | GO:0045872 | positive regulation of rhodopsin gene expression(GO:0045872) |
| 0.0 | 0.1 | GO:0032909 | transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909) |
| 0.0 | 0.5 | GO:0006768 | biotin metabolic process(GO:0006768) |
| 0.0 | 0.2 | GO:0071073 | positive regulation of phospholipid biosynthetic process(GO:0071073) |
| 0.0 | 0.6 | GO:0050884 | neuromuscular process controlling posture(GO:0050884) |
| 0.0 | 0.1 | GO:0035092 | sperm chromatin condensation(GO:0035092) |
| 0.0 | 0.7 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
| 0.0 | 0.1 | GO:0005986 | sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) |
| 0.0 | 0.7 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.0 | 0.2 | GO:1903027 | regulation of opsonization(GO:1903027) |
| 0.0 | 0.2 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
| 0.0 | 0.0 | GO:0007521 | muscle cell fate determination(GO:0007521) |
| 0.0 | 0.1 | GO:0019087 | transformation of host cell by virus(GO:0019087) |
| 0.0 | 0.6 | GO:0002076 | osteoblast development(GO:0002076) |
| 0.0 | 0.8 | GO:0072663 | protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663) |
| 0.0 | 0.1 | GO:0030885 | regulation of myeloid dendritic cell activation(GO:0030885) |
| 0.0 | 0.3 | GO:0034244 | negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
| 0.0 | 0.3 | GO:2000353 | positive regulation of endothelial cell apoptotic process(GO:2000353) |
| 0.0 | 0.1 | GO:2000189 | positive regulation of cholesterol homeostasis(GO:2000189) |
| 0.0 | 1.9 | GO:0019933 | cAMP-mediated signaling(GO:0019933) |
| 0.0 | 0.1 | GO:0034164 | negative regulation of toll-like receptor 9 signaling pathway(GO:0034164) |
| 0.0 | 0.3 | GO:0040033 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
| 0.0 | 0.1 | GO:1904693 | vitellogenesis(GO:0007296) midbrain morphogenesis(GO:1904693) |
| 0.0 | 0.4 | GO:0070734 | histone H3-K27 methylation(GO:0070734) |
| 0.0 | 0.2 | GO:0015705 | iodide transport(GO:0015705) |
| 0.0 | 0.1 | GO:0030240 | skeletal muscle thin filament assembly(GO:0030240) |
| 0.0 | 0.2 | GO:0051599 | response to hydrostatic pressure(GO:0051599) |
| 0.0 | 1.3 | GO:0008088 | axo-dendritic transport(GO:0008088) |
| 0.0 | 0.2 | GO:0043568 | positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) |
| 0.0 | 0.5 | GO:0010603 | regulation of cytoplasmic mRNA processing body assembly(GO:0010603) |
| 0.0 | 0.1 | GO:0090214 | spongiotrophoblast layer developmental growth(GO:0090214) |
| 0.0 | 0.2 | GO:1901529 | positive regulation of anion channel activity(GO:1901529) |
| 0.0 | 0.0 | GO:0060923 | cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) |
| 0.0 | 1.1 | GO:0072384 | organelle transport along microtubule(GO:0072384) |
| 0.0 | 0.4 | GO:0031915 | positive regulation of synaptic plasticity(GO:0031915) |
| 0.0 | 0.1 | GO:0042373 | vitamin K metabolic process(GO:0042373) |
| 0.0 | 0.2 | GO:0090481 | pyrimidine nucleotide-sugar transmembrane transport(GO:0090481) |
| 0.0 | 0.9 | GO:0001541 | ovarian follicle development(GO:0001541) |
| 0.0 | 0.1 | GO:0042427 | serotonin biosynthetic process(GO:0042427) |
| 0.0 | 0.2 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.0 | 0.1 | GO:0021516 | dorsal spinal cord development(GO:0021516) |
| 0.0 | 0.2 | GO:0033299 | secretion of lysosomal enzymes(GO:0033299) |
| 0.0 | 0.6 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.0 | 0.1 | GO:0048570 | notochord morphogenesis(GO:0048570) |
| 0.0 | 0.1 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 0.0 | 1.8 | GO:0031295 | T cell costimulation(GO:0031295) |
| 0.0 | 0.0 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.0 | 0.1 | GO:2001012 | mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012) |
| 0.0 | 0.3 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
| 0.0 | 0.1 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
| 0.0 | 0.2 | GO:0033147 | negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147) |
| 0.0 | 0.4 | GO:0001502 | cartilage condensation(GO:0001502) |
| 0.0 | 0.1 | GO:0021615 | glossopharyngeal nerve morphogenesis(GO:0021615) |
| 0.0 | 0.1 | GO:0010968 | regulation of microtubule nucleation(GO:0010968) |
| 0.0 | 0.2 | GO:1904776 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.0 | 0.1 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.0 | 0.2 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.0 | 0.0 | GO:0060684 | epithelial-mesenchymal cell signaling(GO:0060684) |
| 0.0 | 0.3 | GO:2000114 | regulation of establishment of cell polarity(GO:2000114) |
| 0.0 | 0.4 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.0 | 0.0 | GO:0033031 | positive regulation of neutrophil apoptotic process(GO:0033031) |
| 0.0 | 0.2 | GO:0043651 | linoleic acid metabolic process(GO:0043651) |
| 0.0 | 0.0 | GO:0022012 | smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776) subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) nose morphogenesis(GO:0043585) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875) |
| 0.0 | 0.2 | GO:1901750 | leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750) |
| 0.0 | 0.1 | GO:0007144 | female meiosis I(GO:0007144) |
| 0.0 | 0.4 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
| 0.0 | 0.2 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
| 0.0 | 0.1 | GO:0048840 | otolith development(GO:0048840) |
| 0.0 | 0.4 | GO:0051646 | mitochondrion localization(GO:0051646) |
| 0.0 | 0.2 | GO:0010818 | T cell chemotaxis(GO:0010818) |
| 0.0 | 1.7 | GO:0008037 | cell recognition(GO:0008037) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 4.0 | GO:0044307 | dendritic branch(GO:0044307) |
| 0.7 | 15.2 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.3 | 1.0 | GO:0034657 | GID complex(GO:0034657) |
| 0.3 | 2.6 | GO:0035976 | AP1 complex(GO:0035976) |
| 0.2 | 1.4 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 0.2 | 0.7 | GO:0070701 | mucus layer(GO:0070701) |
| 0.2 | 8.4 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.2 | 7.2 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.2 | 3.7 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.2 | 5.0 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.2 | 0.8 | GO:0032449 | CBM complex(GO:0032449) |
| 0.1 | 7.2 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.1 | 0.8 | GO:0031673 | H zone(GO:0031673) |
| 0.1 | 0.5 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.1 | 0.9 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
| 0.1 | 0.7 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) |
| 0.1 | 0.6 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.1 | 0.7 | GO:0043541 | UDP-N-acetylglucosamine transferase complex(GO:0043541) |
| 0.1 | 4.0 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.1 | 0.7 | GO:0035867 | alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) |
| 0.1 | 18.0 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.1 | 5.9 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.1 | 0.4 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
| 0.1 | 0.4 | GO:0070554 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554) |
| 0.1 | 0.2 | GO:0044609 | DBIRD complex(GO:0044609) |
| 0.1 | 1.5 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.1 | 1.0 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.1 | 1.3 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.1 | 0.3 | GO:0032044 | DSIF complex(GO:0032044) |
| 0.1 | 1.0 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
| 0.1 | 0.8 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.1 | 0.6 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.1 | 2.8 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.1 | 5.4 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.1 | 0.2 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.0 | 0.3 | GO:0033165 | interphotoreceptor matrix(GO:0033165) |
| 0.0 | 0.2 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.0 | 0.3 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.0 | 0.6 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.0 | 2.5 | GO:0043034 | costamere(GO:0043034) |
| 0.0 | 2.8 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.0 | 2.6 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 1.2 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.0 | 0.5 | GO:0097470 | ribbon synapse(GO:0097470) |
| 0.0 | 0.5 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.0 | 0.2 | GO:0071012 | catalytic step 1 spliceosome(GO:0071012) |
| 0.0 | 1.3 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.0 | 0.1 | GO:0031251 | PAN complex(GO:0031251) |
| 0.0 | 1.9 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 2.0 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.0 | 0.4 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.0 | 4.3 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 0.4 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.0 | 0.5 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.0 | 16.1 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 0.3 | GO:0071437 | invadopodium(GO:0071437) |
| 0.0 | 0.2 | GO:0016514 | SWI/SNF complex(GO:0016514) |
| 0.0 | 0.1 | GO:0001534 | radial spoke(GO:0001534) |
| 0.0 | 0.9 | GO:0031305 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 0.0 | 0.3 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.0 | 0.1 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
| 0.0 | 0.3 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.0 | 0.4 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.0 | 2.3 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.0 | 1.8 | GO:0045095 | keratin filament(GO:0045095) |
| 0.0 | 3.3 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.0 | 6.8 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 15.9 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.0 | 0.1 | GO:0005712 | chiasma(GO:0005712) |
| 0.0 | 2.6 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 1.3 | GO:0005747 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.0 | 0.1 | GO:0044218 | growing cell tip(GO:0035838) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279) |
| 0.0 | 0.3 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.0 | 0.2 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 0.0 | 0.4 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.0 | 3.4 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 0.0 | GO:0070939 | Dsl1p complex(GO:0070939) |
| 0.0 | 0.3 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.0 | 0.2 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.0 | 0.1 | GO:0031462 | Cul2-RING ubiquitin ligase complex(GO:0031462) |
| 0.0 | 0.8 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 0.2 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.0 | 0.1 | GO:0014802 | terminal cisterna(GO:0014802) |
| 0.0 | 0.6 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 0.2 | GO:0030904 | retromer complex(GO:0030904) |
| 0.0 | 0.4 | GO:0032982 | myosin filament(GO:0032982) |
| 0.0 | 0.3 | GO:0005605 | basal lamina(GO:0005605) |
| 0.0 | 0.2 | GO:0036057 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.0 | 1.1 | GO:0005604 | basement membrane(GO:0005604) |
| 0.0 | 1.9 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 0.1 | GO:0001673 | male germ cell nucleus(GO:0001673) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 5.0 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
| 1.2 | 4.7 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.9 | 14.6 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.9 | 18.2 | GO:0001087 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.8 | 5.1 | GO:0051033 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.7 | 2.0 | GO:0019959 | interleukin-8 binding(GO:0019959) |
| 0.6 | 5.2 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.5 | 1.6 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
| 0.5 | 2.3 | GO:0004719 | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) |
| 0.4 | 1.3 | GO:0036487 | nitric-oxide synthase inhibitor activity(GO:0036487) |
| 0.4 | 2.6 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 0.4 | 2.2 | GO:0051996 | farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996) |
| 0.4 | 4.0 | GO:0004300 | enoyl-CoA hydratase activity(GO:0004300) |
| 0.4 | 1.8 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.3 | 2.0 | GO:0050659 | N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659) |
| 0.3 | 1.3 | GO:0008427 | calcium-dependent protein kinase inhibitor activity(GO:0008427) |
| 0.3 | 3.9 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.3 | 4.5 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.3 | 1.3 | GO:0030226 | apolipoprotein receptor activity(GO:0030226) |
| 0.3 | 5.6 | GO:0055106 | ubiquitin-protein transferase regulator activity(GO:0055106) |
| 0.3 | 1.2 | GO:0047708 | biotinidase activity(GO:0047708) |
| 0.3 | 1.1 | GO:0005169 | neurotrophin TRKB receptor binding(GO:0005169) |
| 0.3 | 2.0 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
| 0.3 | 3.5 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.3 | 4.5 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) |
| 0.3 | 0.8 | GO:0008267 | poly-glutamine tract binding(GO:0008267) |
| 0.2 | 0.7 | GO:0008424 | glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921) |
| 0.2 | 0.7 | GO:0033878 | hormone-sensitive lipase activity(GO:0033878) |
| 0.2 | 0.7 | GO:0005010 | insulin-like growth factor-activated receptor activity(GO:0005010) |
| 0.2 | 0.7 | GO:0004577 | N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity(GO:0004577) |
| 0.2 | 4.1 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.2 | 4.1 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.2 | 0.8 | GO:1902122 | chenodeoxycholic acid binding(GO:1902122) |
| 0.2 | 1.0 | GO:0070653 | high-density lipoprotein particle receptor binding(GO:0070653) |
| 0.2 | 1.5 | GO:0005534 | galactose binding(GO:0005534) |
| 0.2 | 5.8 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.2 | 0.9 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.2 | 6.8 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.2 | 1.4 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 0.2 | 2.1 | GO:0008430 | selenium binding(GO:0008430) |
| 0.2 | 0.5 | GO:0055100 | adiponectin binding(GO:0055100) |
| 0.1 | 0.6 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.1 | 0.9 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.1 | 1.6 | GO:0102336 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.1 | 0.4 | GO:0005174 | CD40 receptor binding(GO:0005174) |
| 0.1 | 3.3 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.1 | 0.4 | GO:0015218 | pyrimidine nucleotide transmembrane transporter activity(GO:0015218) |
| 0.1 | 1.4 | GO:0050692 | DBD domain binding(GO:0050692) |
| 0.1 | 0.5 | GO:0010858 | calcium-dependent protein kinase regulator activity(GO:0010858) |
| 0.1 | 2.6 | GO:0046965 | retinoid X receptor binding(GO:0046965) |
| 0.1 | 0.7 | GO:0010465 | nerve growth factor receptor activity(GO:0010465) |
| 0.1 | 0.5 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
| 0.1 | 0.7 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
| 0.1 | 0.6 | GO:0010861 | thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375) |
| 0.1 | 0.4 | GO:0047493 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.1 | 8.0 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.1 | 6.9 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.1 | 2.8 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.1 | 0.4 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
| 0.1 | 0.6 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 0.1 | 2.8 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.1 | 2.9 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.1 | 0.7 | GO:0043426 | MRF binding(GO:0043426) |
| 0.1 | 0.3 | GO:0004504 | peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598) |
| 0.1 | 0.3 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
| 0.1 | 1.1 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.1 | 0.4 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 0.1 | 0.9 | GO:0016634 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634) |
| 0.1 | 0.6 | GO:0086083 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083) |
| 0.1 | 0.7 | GO:0008525 | phosphatidylcholine transporter activity(GO:0008525) |
| 0.1 | 0.5 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 0.1 | 5.0 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
| 0.1 | 0.8 | GO:0070915 | lysophosphatidic acid receptor activity(GO:0070915) |
| 0.1 | 1.7 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.1 | 0.3 | GO:1902444 | riboflavin binding(GO:1902444) |
| 0.1 | 2.9 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.1 | 0.9 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.1 | 0.6 | GO:0071253 | connexin binding(GO:0071253) |
| 0.1 | 0.1 | GO:1904713 | beta-catenin destruction complex binding(GO:1904713) |
| 0.1 | 1.0 | GO:0015280 | ligand-gated sodium channel activity(GO:0015280) |
| 0.1 | 1.3 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.1 | 1.2 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.1 | 1.8 | GO:0005521 | lamin binding(GO:0005521) |
| 0.1 | 2.6 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.1 | 0.6 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.1 | 2.0 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.1 | 0.3 | GO:0004096 | catalase activity(GO:0004096) |
| 0.1 | 0.2 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
| 0.0 | 6.7 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
| 0.0 | 0.4 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 0.0 | 0.7 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.0 | 1.5 | GO:0008198 | ferrous iron binding(GO:0008198) |
| 0.0 | 0.3 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
| 0.0 | 0.7 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.0 | 0.5 | GO:0043559 | insulin binding(GO:0043559) |
| 0.0 | 1.6 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
| 0.0 | 0.2 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
| 0.0 | 2.5 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.0 | 0.8 | GO:0017110 | nucleoside-diphosphatase activity(GO:0017110) |
| 0.0 | 0.4 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.0 | 0.2 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
| 0.0 | 0.1 | GO:0035651 | AP-3 adaptor complex binding(GO:0035651) |
| 0.0 | 0.4 | GO:0047623 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.0 | 1.3 | GO:0019198 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.0 | 0.6 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.0 | 1.2 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.0 | 0.5 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.0 | 0.5 | GO:0031432 | titin binding(GO:0031432) |
| 0.0 | 0.2 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 0.0 | 0.6 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.0 | 0.3 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
| 0.0 | 0.4 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.0 | 0.2 | GO:0015235 | cobalamin transporter activity(GO:0015235) |
| 0.0 | 0.1 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 0.0 | 1.2 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 3.8 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 0.0 | 1.1 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.0 | 6.5 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.0 | 0.5 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.0 | 0.1 | GO:0042132 | fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132) |
| 0.0 | 0.2 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.0 | 1.1 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.0 | 0.3 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) |
| 0.0 | 0.6 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.0 | 0.1 | GO:0003696 | satellite DNA binding(GO:0003696) |
| 0.0 | 0.2 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
| 0.0 | 0.9 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.0 | 0.8 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.0 | 0.2 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.0 | 0.1 | GO:0000386 | second spliceosomal transesterification activity(GO:0000386) |
| 0.0 | 0.8 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.0 | 0.6 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 0.0 | 1.3 | GO:0050136 | NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.0 | 1.3 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.0 | 0.1 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 0.0 | 0.6 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.0 | 10.6 | GO:0003682 | chromatin binding(GO:0003682) |
| 0.0 | 0.1 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
| 0.0 | 0.1 | GO:0004090 | carbonyl reductase (NADPH) activity(GO:0004090) |
| 0.0 | 0.1 | GO:0050528 | acyloxyacyl hydrolase activity(GO:0050528) |
| 0.0 | 0.5 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.0 | 1.1 | GO:0043531 | ADP binding(GO:0043531) |
| 0.0 | 0.1 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
| 0.0 | 0.2 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.0 | 0.3 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.0 | 0.2 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.0 | 0.2 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 0.0 | 0.7 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.0 | 4.0 | GO:0004866 | endopeptidase inhibitor activity(GO:0004866) |
| 0.0 | 0.3 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.0 | 0.0 | GO:0004796 | thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134) |
| 0.0 | 0.1 | GO:0052594 | tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596) |
| 0.0 | 0.1 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.0 | 0.1 | GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) |
| 0.0 | 0.1 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
| 0.0 | 0.2 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
| 0.0 | 0.2 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.0 | 0.2 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
| 0.0 | 0.2 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 0.0 | 0.2 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.0 | 0.2 | GO:0005542 | folic acid binding(GO:0005542) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 20.6 | PID GMCSF PATHWAY | GMCSF-mediated signaling events |
| 0.2 | 21.7 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 7.2 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.1 | 3.0 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.1 | 8.3 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.1 | 1.0 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.1 | 3.9 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.1 | 6.8 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.1 | 6.6 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.1 | 9.0 | PID E2F PATHWAY | E2F transcription factor network |
| 0.1 | 4.2 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.1 | 3.6 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.1 | 3.5 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.1 | 3.7 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.1 | 1.8 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.1 | 0.9 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.0 | 4.4 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 1.9 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.0 | 0.8 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.0 | 0.8 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.0 | 0.9 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.0 | 1.7 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 1.7 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 0.6 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.0 | 0.3 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
| 0.0 | 0.8 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 1.2 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 0.8 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 0.2 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.0 | 0.3 | PID S1P S1P3 PATHWAY | S1P3 pathway |
| 0.0 | 0.5 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 0.7 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 0.6 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 0.6 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.0 | 0.5 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.0 | 0.9 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.0 | 0.8 | PID FOXO PATHWAY | FoxO family signaling |
| 0.0 | 1.1 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.0 | 1.0 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 0.2 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.0 | 0.3 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.0 | 0.2 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.0 | 0.2 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.0 | 0.5 | PID P53 REGULATION PATHWAY | p53 pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 17.9 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.3 | 4.1 | REACTOME IRAK1 RECRUITS IKK COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 0.3 | 22.6 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.3 | 5.2 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.2 | 3.1 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.2 | 4.7 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
| 0.1 | 3.1 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 0.1 | 1.5 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.1 | 4.0 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.1 | 3.2 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.1 | 7.3 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.1 | 0.7 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.1 | 4.4 | REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
| 0.1 | 3.5 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.1 | 9.4 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.1 | 4.5 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.1 | 0.5 | REACTOME SHC RELATED EVENTS | Genes involved in SHC-related events |
| 0.1 | 0.2 | REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS | Genes involved in NRIF signals cell death from the nucleus |
| 0.1 | 1.0 | REACTOME SIGNALING BY NOTCH4 | Genes involved in Signaling by NOTCH4 |
| 0.1 | 5.6 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.1 | 3.0 | REACTOME CA DEPENDENT EVENTS | Genes involved in Ca-dependent events |
| 0.1 | 2.6 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.1 | 3.3 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.1 | 2.2 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.1 | 4.7 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.0 | 1.4 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 0.9 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.0 | 1.8 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.0 | 1.6 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 0.6 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.0 | 0.3 | REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL | Genes involved in NF-kB is activated and signals survival |
| 0.0 | 1.2 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.0 | 0.4 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 0.0 | 0.8 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
| 0.0 | 0.4 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.0 | 1.4 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 0.3 | REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX | Genes involved in TRAF6 mediated induction of TAK1 complex |
| 0.0 | 0.5 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.0 | 2.0 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 0.5 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.0 | 0.2 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.0 | 1.2 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 3.8 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 0.7 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.0 | 0.3 | REACTOME REGULATORY RNA PATHWAYS | Genes involved in Regulatory RNA pathways |
| 0.0 | 0.7 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.0 | 0.7 | REACTOME ANTIGEN PROCESSING CROSS PRESENTATION | Genes involved in Antigen processing-Cross presentation |
| 0.0 | 2.1 | REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR | Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR) |
| 0.0 | 0.4 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.0 | 0.3 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.0 | 0.5 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.0 | 1.3 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.0 | 0.4 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.0 | 0.6 | REACTOME PERK REGULATED GENE EXPRESSION | Genes involved in PERK regulated gene expression |
| 0.0 | 0.5 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.0 | 0.2 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.0 | 0.2 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.0 | 0.3 | REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS | Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis |
| 0.0 | 1.3 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.0 | 0.2 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 0.0 | 0.3 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |