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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for FOXJ2

Z-value: 0.61

Motif logo

Transcription factors associated with FOXJ2

Gene Symbol Gene ID Gene Info
ENSG00000065970.9 FOXJ2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXJ2hg38_v1_chr12_+_8032692_8032744-0.471.8e-02Click!

Activity profile of FOXJ2 motif

Sorted Z-values of FOXJ2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXJ2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr15_+_67138001 3.81 ENST00000439724.7
SMAD family member 3
chr8_+_103371490 1.75 ENST00000330295.10
ENST00000415886.2
collagen triple helix repeat containing 1
chr2_+_161160299 1.69 ENST00000440506.5
ENST00000429217.5
ENST00000406287.5
ENST00000402568.5
TRAF family member associated NFKB activator
chr21_-_34526850 1.54 ENST00000481448.5
ENST00000381132.6
regulator of calcineurin 1
chr11_+_35180279 1.11 ENST00000531873.5
CD44 molecule (Indian blood group)
chr9_+_5510492 1.02 ENST00000397747.5
programmed cell death 1 ligand 2
chr2_+_161160420 0.96 ENST00000392749.7
ENST00000405852.5
TRAF family member associated NFKB activator
chr21_-_34526815 0.92 ENST00000492600.1
regulator of calcineurin 1
chr1_-_220089818 0.87 ENST00000498791.6
ENST00000480959.6
3'(2'), 5'-bisphosphate nucleotidase 1
chr11_+_35180342 0.85 ENST00000639002.1
CD44 molecule (Indian blood group)
chr16_-_58546702 0.81 ENST00000567133.1
CCR4-NOT transcription complex subunit 1
chr21_-_26051023 0.75 ENST00000415997.1
amyloid beta precursor protein
chr9_-_131740056 0.74 ENST00000372195.5
ENST00000683357.1
Rap guanine nucleotide exchange factor 1
chr2_+_201116143 0.69 ENST00000443227.5
ENST00000309955.8
ENST00000341222.10
ENST00000341582.10
CASP8 and FADD like apoptosis regulator
chr19_+_9087061 0.55 ENST00000641627.1
olfactory receptor family 1 subfamily M member 1
chr6_+_30571393 0.54 ENST00000376545.7
ENST00000441867.6
ENST00000468958.1
ENST00000326195.13
ATP binding cassette subfamily F member 1
chr17_+_27631148 0.52 ENST00000313648.10
ENST00000395473.7
ENST00000577392.5
ENST00000584661.5
galectin 9
chr9_+_100429511 0.50 ENST00000613183.1
Myb/SANT DNA binding domain containing 3
chrX_+_109537118 0.50 ENST00000372103.1
nuclear transport factor 2 like export factor 2
chr11_-_57322197 0.48 ENST00000532437.1
tankyrase 1 binding protein 1
chr6_+_31494881 0.46 ENST00000538442.5
MHC class I polypeptide-related sequence B
chr19_-_7058640 0.44 ENST00000333843.8
methyl-CpG binding domain protein 3 like 3
chr7_-_102642791 0.44 ENST00000340457.8
uroplakin 3B like 1
chr8_+_38728186 0.44 ENST00000519416.5
ENST00000520615.5
transforming acidic coiled-coil containing protein 1
chr4_+_87975829 0.42 ENST00000614857.5
secreted phosphoprotein 1
chr7_-_115968302 0.42 ENST00000457268.5
transcription factor EC
chr19_+_7030578 0.41 ENST00000329753.5
methyl-CpG binding domain protein 3 like 5
chr7_+_23598144 0.40 ENST00000410069.1
coiled-coil domain containing 126
chr19_-_7040179 0.40 ENST00000381394.9
methyl-CpG binding domain protein 3 like 4
chr17_+_68515399 0.40 ENST00000588188.6
protein kinase cAMP-dependent type I regulatory subunit alpha
chr15_+_73873604 0.40 ENST00000535547.6
ENST00000562056.1
TBC1 domain family member 21
chr11_-_82845734 0.39 ENST00000681883.1
ENST00000680040.1
ENST00000681432.1
prolylcarboxypeptidase
chr9_-_96655280 0.39 ENST00000446045.1
ENST00000375234.8
peroxiredoxin like 2C
chr3_+_157436842 0.38 ENST00000295927.4
pentraxin 3
chrX_-_6535118 0.37 ENST00000381089.7
ENST00000612369.4
ENST00000398729.1
variable charge X-linked 3A
chr6_+_10887036 0.37 ENST00000283141.11
synaptonemal complex protein 2 like
chr1_+_160796098 0.36 ENST00000392203.8
lymphocyte antigen 9
chr8_+_100158029 0.36 ENST00000251809.4
sperm associated antigen 1
chr1_+_160796070 0.35 ENST00000368037.9
lymphocyte antigen 9
chr1_+_150149819 0.35 ENST00000369124.5
pleckstrin homology domain containing O1
chr12_-_10098940 0.35 ENST00000420265.2
C-type lectin domain family 1 member A
chr7_-_33100886 0.35 ENST00000448915.1
RP9 pre-mRNA splicing factor
chr10_+_116545907 0.35 ENST00000369221.2
pancreatic lipase
chr8_-_33567118 0.34 ENST00000256257.2
ring finger protein 122
chr4_+_67558719 0.34 ENST00000265404.7
ENST00000396225.1
signal transducing adaptor family member 1
chr20_-_43726989 0.34 ENST00000373003.2
gametocyte specific factor 1 like
chr11_-_82846128 0.33 ENST00000679809.1
ENST00000680186.1
ENST00000681592.1
prolylcarboxypeptidase
chr10_+_84230660 0.32 ENST00000652073.1
retinal G protein coupled receptor
chr14_+_88005128 0.32 ENST00000267549.5
G protein-coupled receptor 65
chr9_-_127916978 0.31 ENST00000361444.3
ENST00000335791.10
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr12_-_52680398 0.31 ENST00000252244.3
keratin 1
chr15_+_66505289 0.31 ENST00000565627.5
ENST00000564179.5
ENST00000307897.10
zwilch kinetochore protein
chr2_+_100974849 0.31 ENST00000450763.1
neuronal PAS domain protein 2
chr15_+_73873557 0.30 ENST00000300504.7
TBC1 domain family member 21
chr2_+_209653171 0.30 ENST00000447185.5
microtubule associated protein 2
chr1_-_72100930 0.29 ENST00000306821.3
neuronal growth regulator 1
chr12_-_10098977 0.29 ENST00000315330.8
ENST00000457018.6
C-type lectin domain family 1 member A
chr15_+_66504959 0.29 ENST00000535141.6
ENST00000613446.4
ENST00000446801.6
zwilch kinetochore protein
chr6_-_167157980 0.28 ENST00000366834.2
G protein-coupled receptor 31
chr1_+_44746401 0.28 ENST00000372217.5
kinesin family member 2C
chr19_+_54497879 0.27 ENST00000412608.5
ENST00000610651.1
leukocyte associated immunoglobulin like receptor 2
chr16_-_30429207 0.26 ENST00000568434.1
dCTP pyrophosphatase 1
chr3_-_190449782 0.26 ENST00000354905.3
transmembrane protein 207
chr17_-_58417521 0.26 ENST00000584437.5
ENST00000407977.7
ring finger protein 43
chr17_-_41168219 0.26 ENST00000391356.4
keratin associated protein 4-3
chr10_-_25062279 0.25 ENST00000615958.4
enkurin, TRPC channel interacting protein
chr9_-_21141832 0.25 ENST00000380229.4
interferon omega 1
chr17_+_39461468 0.25 ENST00000447079.6
ENST00000584632.5
cyclin dependent kinase 12
chr11_+_63369779 0.24 ENST00000279178.4
solute carrier family 22 member 9
chrX_+_109535775 0.24 ENST00000218004.5
nuclear transport factor 2 like export factor 2
chr1_-_43389768 0.24 ENST00000372455.4
ENST00000372457.9
ENST00000290663.10
mediator complex subunit 8
chr17_-_58417547 0.24 ENST00000577716.5
ring finger protein 43
chr10_-_72626111 0.24 ENST00000604238.2
ENST00000642044.1
ENST00000635239.1
ENST00000398761.8
mitochondrial calcium uptake 1
chr16_+_57413861 0.23 ENST00000616880.1
C-C motif chemokine ligand 17
chr21_-_36079382 0.23 ENST00000399201.5
SET domain containing 4
chr19_+_11547840 0.23 ENST00000588935.1
calponin 1
chr1_-_27626229 0.22 ENST00000399173.5
FGR proto-oncogene, Src family tyrosine kinase
chr12_+_108129276 0.22 ENST00000547525.6
WSC domain containing 2
chr7_+_99828010 0.22 ENST00000631161.2
ENST00000354829.7
ENST00000342499.8
ENST00000417625.5
ENST00000415413.5
ENST00000444905.5
ENST00000222382.5
ENST00000312017.9
cytochrome P450 family 3 subfamily A member 43
chr4_-_47981535 0.21 ENST00000402813.9
cyclic nucleotide gated channel subunit alpha 1
chr15_-_55588937 0.21 ENST00000302000.10
pygopus family PHD finger 1
chr3_+_49007365 0.21 ENST00000608424.6
ENST00000438660.5
ENST00000415265.6
WD repeat domain 6
chr3_-_44510602 0.21 ENST00000436261.6
zinc finger protein 852
chr1_+_162069768 0.20 ENST00000530878.5
nitric oxide synthase 1 adaptor protein
chr3_+_179148341 0.20 ENST00000263967.4
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
chr9_+_105662457 0.19 ENST00000334077.6
TAL bHLH transcription factor 2
chr16_-_18896874 0.19 ENST00000565324.5
ENST00000561947.5
SMG1 nonsense mediated mRNA decay associated PI3K related kinase
chr3_+_57890011 0.19 ENST00000494088.6
ENST00000438794.5
sarcolemma associated protein
chr1_+_162069674 0.19 ENST00000361897.10
nitric oxide synthase 1 adaptor protein
chr11_+_64318091 0.19 ENST00000265462.9
ENST00000352435.8
ENST00000347941.4
peroxiredoxin 5
chr15_-_34336749 0.19 ENST00000397707.6
ENST00000560611.5
solute carrier family 12 member 6
chr1_+_50105666 0.18 ENST00000651347.1
ELAV like RNA binding protein 4
chr8_+_30387064 0.18 ENST00000523115.5
ENST00000519647.5
RNA binding protein, mRNA processing factor
chr19_+_54115726 0.18 ENST00000445811.5
ENST00000321030.9
ENST00000445124.5
ENST00000447810.5
pre-mRNA processing factor 31
chr9_+_113444725 0.18 ENST00000374140.6
regulator of G protein signaling 3
chr1_+_35869750 0.18 ENST00000373206.5
argonaute RISC component 1
chr10_+_59176600 0.18 ENST00000373880.9
phytanoyl-CoA 2-hydroxylase interacting protein like
chr11_+_27055215 0.17 ENST00000525090.1
gamma-butyrobetaine hydroxylase 1
chr1_+_224183197 0.17 ENST00000323699.9
delta 4-desaturase, sphingolipid 1
chr2_-_85414039 0.17 ENST00000447219.6
ENST00000409670.5
ENST00000409724.5
capping actin protein, gelsolin like
chr11_-_5516690 0.17 ENST00000380184.2
ubiquilin like
chr1_+_43389889 0.16 ENST00000562955.2
ENST00000634258.3
SZT2 subunit of KICSTOR complex
chr3_+_128726151 0.16 ENST00000675342.1
ENST00000493186.6
ENST00000674748.1
ENST00000265062.8
ENST00000482525.5
RAB7A, member RAS oncogene family
chr12_+_54497712 0.15 ENST00000293373.11
NCK associated protein 1 like
chr11_-_16356538 0.15 ENST00000683767.1
SRY-box transcription factor 6
chr4_+_95051671 0.15 ENST00000440890.7
bone morphogenetic protein receptor type 1B
chr17_+_75633420 0.14 ENST00000375215.3
small integral membrane protein 5
chr11_-_125680869 0.13 ENST00000527795.1
acrosomal vesicle protein 1
chr1_+_239719542 0.13 ENST00000448020.1
cholinergic receptor muscarinic 3
chrX_+_55717796 0.13 ENST00000262850.7
Ras related GTP binding B
chr2_-_206086057 0.13 ENST00000403263.6
INO80 complex subunit D
chr15_-_55196608 0.13 ENST00000677989.1
ENST00000562895.2
ENST00000569386.2
ribosomal L24 domain containing 1
chr3_+_63443076 0.13 ENST00000295894.9
synaptoporin
chr1_-_27374816 0.13 ENST00000270879.9
ENST00000354982.2
ficolin 3
chr1_-_217076889 0.13 ENST00000493748.5
ENST00000463665.5
estrogen related receptor gamma
chr10_+_103245887 0.13 ENST00000441178.2
ribulose-5-phosphate-3-epimerase like 1
chr4_-_119322128 0.13 ENST00000274024.4
fatty acid binding protein 2
chr17_+_17782108 0.12 ENST00000395774.1
retinoic acid induced 1
chr17_+_28719972 0.12 ENST00000422514.7
ribosomal protein L23a
chr6_-_130222813 0.12 ENST00000437477.6
ENST00000439090.7
sterile alpha motif domain containing 3
chr12_-_8662619 0.12 ENST00000544889.1
ENST00000543369.5
microfibril associated protein 5
chr3_+_172039556 0.12 ENST00000415807.7
ENST00000421757.5
fibronectin type III domain containing 3B
chr7_+_133253064 0.11 ENST00000393161.6
ENST00000253861.5
exocyst complex component 4
chr12_-_8662703 0.11 ENST00000535336.5
microfibril associated protein 5
chr4_-_41748713 0.11 ENST00000226382.4
paired like homeobox 2B
chr3_-_57199938 0.11 ENST00000473921.2
ENST00000295934.8
HESX homeobox 1
chr7_+_8433602 0.11 ENST00000405863.6
neurexophilin 1
chrX_-_80809854 0.11 ENST00000373275.5
bromodomain and WD repeat domain containing 3
chr4_-_122621011 0.11 ENST00000611104.2
ENST00000648588.1
interleukin 21
chr15_+_64136330 0.11 ENST00000560861.1
sorting nexin 1
chr12_-_102480552 0.11 ENST00000337514.11
ENST00000307046.8
insulin like growth factor 1
chr3_+_128726130 0.11 ENST00000676425.1
ENST00000675864.1
RAB7A, member RAS oncogene family
chr1_+_160796157 0.11 ENST00000263285.11
ENST00000368039.2
lymphocyte antigen 9
chr10_-_104232301 0.11 ENST00000369720.6
ENST00000369719.2
ENST00000278064.7
ENST00000357060.8
cilia and flagella associated protein 43
chr1_-_152325232 0.10 ENST00000368799.2
filaggrin
chr6_-_26123910 0.10 ENST00000314332.5
ENST00000396984.1
H2B clustered histone 4
chr16_+_3018390 0.10 ENST00000573001.5
TNF receptor superfamily member 12A
chr11_-_57649894 0.10 ENST00000534810.3
ENST00000300022.8
yippee like 4
chr14_+_36657560 0.10 ENST00000402703.6
paired box 9
chr20_+_34194569 0.10 ENST00000568305.5
agouti signaling protein
chr17_+_4788926 0.10 ENST00000331264.8
glycolipid transfer protein domain containing 2
chr3_-_149221811 0.10 ENST00000455472.3
ENST00000264613.11
ceruloplasmin
chr9_+_5890872 0.10 ENST00000381477.8
ENST00000381476.5
ENST00000381471.1
melan-A
chr11_-_57649932 0.09 ENST00000524669.5
yippee like 4
chr6_+_33454543 0.09 ENST00000621915.1
ENST00000395064.3
zinc finger and BTB domain containing 9
chr9_+_130693756 0.09 ENST00000546165.5
ENST00000372352.7
ENST00000372358.10
ENST00000372351.7
ENST00000372350.7
ENST00000495699.2
exosome component 2
chr6_+_29457155 0.09 ENST00000377133.6
ENST00000377136.5
olfactory receptor family 2 subfamily H member 1
chr7_-_56106444 0.09 ENST00000395422.4
coiled-coil-helix-coiled-coil-helix domain containing 2
chr3_+_49007062 0.09 ENST00000395474.7
ENST00000610967.4
ENST00000429900.6
WD repeat domain 6
chrX_+_55717733 0.08 ENST00000414239.5
ENST00000374941.9
Ras related GTP binding B
chr10_+_116621306 0.08 ENST00000611850.4
ENST00000591655.3
pancreatic lipase related protein 2 (gene/pseudogene)
chr6_-_24666591 0.08 ENST00000341060.3
tyrosyl-DNA phosphodiesterase 2
chr5_-_64768619 0.08 ENST00000513458.9
SREK1 interacting protein 1
chr6_-_52763473 0.08 ENST00000493422.3
glutathione S-transferase alpha 2
chr7_+_73827737 0.08 ENST00000435050.1
claudin 4
chr3_-_109337572 0.07 ENST00000335658.6
developmental pluripotency associated 4
chr17_-_28406160 0.07 ENST00000618626.1
ENST00000612814.5
solute carrier family 46 member 1
chr9_-_26892732 0.07 ENST00000333916.8
ENST00000520187.1
caspase activity and apoptosis inhibitor 1
chr3_+_51983438 0.06 ENST00000476351.5
ENST00000476854.5
ENST00000494103.5
ENST00000404366.7
ENST00000635797.1
ENST00000636358.2
ENST00000469863.1
aminoacylase 1
chr11_+_61430100 0.06 ENST00000542074.1
ENST00000534878.5
ENST00000301761.7
ENST00000537782.5
ENST00000543265.1
succinate dehydrogenase complex assembly factor 2
chr2_-_74392025 0.06 ENST00000440727.1
ENST00000409240.5
dynactin subunit 1
chr14_+_90397019 0.06 ENST00000447653.8
ENST00000356978.9
ENST00000626705.2
calmodulin 1
chr15_-_80252205 0.06 ENST00000560778.3
cortexin domain containing 1
chrX_-_53422170 0.05 ENST00000675504.1
structural maintenance of chromosomes 1A
chr18_+_3447562 0.05 ENST00000618001.4
TGFB induced factor homeobox 1
chr6_+_31114793 0.05 ENST00000259881.10
psoriasis susceptibility 1 candidate 1
chr2_-_89160329 0.05 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr1_-_37554277 0.05 ENST00000296215.8
Smad nuclear interacting protein 1
chr13_-_37598750 0.05 ENST00000379743.8
ENST00000379742.4
ENST00000379749.8
ENST00000379747.9
ENST00000541179.5
ENST00000541481.5
periostin
chr13_-_46142834 0.05 ENST00000674665.1
lymphocyte cytosolic protein 1
chr11_+_120210991 0.05 ENST00000328965.9
out at first homolog
chrX_+_80335504 0.05 ENST00000538312.5
terminal nucleotidyltransferase 5D
chr1_-_179877790 0.04 ENST00000495650.1
ENST00000367612.7
ENST00000482587.5
ENST00000609928.6
torsin 1A interacting protein 2
chr19_-_55363243 0.04 ENST00000424985.3
family with sequence similarity 71 member E2
chr8_+_47961028 0.04 ENST00000650216.1
minichromosome maintenance complex component 4
chr4_-_67883987 0.04 ENST00000283916.11
transmembrane serine protease 11D
chr6_+_10747753 0.04 ENST00000612333.4
transmembrane protein 14B
chr17_-_41184895 0.04 ENST00000620667.1
ENST00000398472.2
keratin associated protein 4-1
chr1_-_216805367 0.04 ENST00000360012.7
estrogen related receptor gamma
chr12_-_68159732 0.04 ENST00000229135.4
interferon gamma
chr4_-_38804783 0.04 ENST00000308979.7
ENST00000505940.1
ENST00000515861.5
toll like receptor 1
chr6_+_10747765 0.04 ENST00000461342.5
ENST00000475942.5
ENST00000379542.10
ENST00000379530.7
ENST00000473276.5
ENST00000481240.5
ENST00000467317.5
transmembrane protein 14B
chr17_-_81947233 0.03 ENST00000409745.2
myeloid associated differentiation marker like 2
chr12_+_21526287 0.03 ENST00000256969.7
spexin hormone
chr14_+_37795308 0.03 ENST00000267368.11
ENST00000382320.4
tetratricopeptide repeat domain 6
chr1_+_32274111 0.03 ENST00000619559.4
ENST00000461712.6
ENST00000373562.7
ENST00000477031.6
ENST00000373557.6
ENST00000333070.4
LCK proto-oncogene, Src family tyrosine kinase
chrX_+_8464830 0.03 ENST00000453306.4
ENST00000381032.6
ENST00000444481.3
variable charge X-linked 3B
chr2_-_24123251 0.03 ENST00000313213.5
ENST00000436622.1
profilin family member 4
chr7_-_101211672 0.02 ENST00000454310.5
procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
chr19_+_49363074 0.02 ENST00000597873.5
dickkopf like acrosomal protein 1
chr17_+_28719995 0.02 ENST00000496182.5
ribosomal protein L23a
chr2_+_231056845 0.01 ENST00000677230.1
ENST00000677259.1
ENST00000677180.1
ENST00000409643.6
ENST00000619128.5
ENST00000678679.1
ENST00000676740.1
ENST00000308696.11
ENST00000440838.5
ENST00000373635.9
proteasome 26S subunit, non-ATPase 1
chr3_+_26694499 0.01 ENST00000456208.2
leucine rich repeat containing 3B
chr19_+_13023958 0.01 ENST00000587760.5
ENST00000585575.5
nuclear factor I X
chr17_-_66229380 0.01 ENST00000205948.11
apolipoprotein H
chr4_-_159035226 0.01 ENST00000434826.3
chromosome 4 open reading frame 45
chr20_+_37744630 0.01 ENST00000373473.5
catenin beta like 1
chr2_+_90021567 0.01 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr12_+_27710795 0.01 ENST00000081029.8
ENST00000538315.5
ENST00000542791.1
mitochondrial ribosomal protein S35
chr17_+_28720224 0.00 ENST00000394938.8
ENST00000394935.7
ENST00000355731.8
ribosomal protein L23a

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.8 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.4 2.6 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.2 1.7 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.2 0.6 GO:0032831 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.2 2.0 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.4 GO:1903947 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.1 0.4 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.1 0.8 GO:0048669 microglia differentiation(GO:0014004) microglia development(GO:0014005) collateral sprouting in absence of injury(GO:0048669) smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.5 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.3 GO:1903973 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.1 0.4 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 1.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.7 GO:0002353 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.1 0.3 GO:0007174 epidermal growth factor catabolic process(GO:0007174)
0.1 0.8 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.2 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.1 0.7 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.5 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.1 0.3 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.1 0.2 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 2.4 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 1.3 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.9 GO:0032740 positive regulation of interleukin-17 production(GO:0032740)
0.0 0.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.1 GO:0003358 noradrenergic neuron development(GO:0003358)
0.0 0.1 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.7 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.2 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.2 GO:1990253 positive regulation of TORC1 signaling(GO:1904263) cellular response to leucine starvation(GO:1990253)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.3 GO:0051451 myoblast migration(GO:0051451)
0.0 0.2 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.1 GO:1902731 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.0 0.1 GO:0019376 galactolipid catabolic process(GO:0019376)
0.0 0.1 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.0 0.0 GO:0070340 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.0 0.1 GO:0000459 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467) CUT catabolic process(GO:0071034) nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038) CUT metabolic process(GO:0071043)
0.0 0.4 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:0034553 mitochondrial electron transport, succinate to ubiquinone(GO:0006121) respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052) pentose catabolic process(GO:0019323)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.3 GO:0051775 response to redox state(GO:0051775)
0.0 0.1 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.0 GO:1990523 bone regeneration(GO:1990523)
0.0 0.2 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.3 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.2 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.5 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.2 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.1 GO:0051958 methotrexate transport(GO:0051958)
0.0 0.1 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.3 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.8 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 2.0 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.6 GO:1990423 RZZ complex(GO:1990423)
0.1 0.3 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.3 GO:0032419 extrinsic component of lysosome membrane(GO:0032419)
0.1 0.8 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 0.4 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.8 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.7 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.3 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952) nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.0 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.2 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 1.3 GO:0005581 collagen trimer(GO:0005581)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.8 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.4 2.6 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.3 2.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.5 GO:0048030 disaccharide binding(GO:0048030)
0.1 0.8 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.5 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.4 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.2 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.1 0.7 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 2.2 GO:0005109 frizzled binding(GO:0005109)
0.0 2.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.5 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0004750 ribulose-phosphate 3-epimerase activity(GO:0004750)
0.0 0.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.2 GO:0030622 U4atac snRNA binding(GO:0030622)
0.0 0.3 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 1.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.7 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.0 0.1 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 0.3 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.2 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.0 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.1 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0015350 methotrexate transporter activity(GO:0015350)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 2.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 2.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.9 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.4 PID AVB3 OPN PATHWAY Osteopontin-mediated events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 2.0 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 2.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.7 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB