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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for FOXQ1

Z-value: 0.83

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Transcription factors associated with FOXQ1

Gene Symbol Gene ID Gene Info
FOXQ1
ENSG00000164379.7 FOXQ1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXQ1hg38_v1_chr6_+_1312090_1312105-0.404.9e-02Click!

Activity profile of FOXQ1 motif

Sorted Z-values of FOXQ1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXQ1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_-_185775271 3.90 ENST00000430503.5
ENST00000319454.10
ENST00000450341.5
SORBS2
sorbin and SH3 domain containing 2
chr4_+_41613476 3.55 ENST00000508466.1
LIMCH1
LIM and calponin homology domains 1
chr1_+_61077219 3.43 ENST00000407417.7
NFIA
nuclear factor I A
chr4_-_69760596 2.97 ENST00000510821.1
SULT1B1
sulfotransferase family 1B member 1
chr1_+_84164370 2.90 ENST00000446538.5
ENST00000610703.4
ENST00000370682.7
ENST00000394838.6
ENST00000432111.5
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr1_+_84164962 2.26 ENST00000614872.4
ENST00000394839.6
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr21_-_26573211 2.23 ENST00000299340.9
ENST00000652641.2
CYYR1
cysteine and tyrosine rich 1
chr8_-_3409528 2.10 ENST00000335551.11
CSMD1
CUB and Sushi multiple domains 1
chr9_-_72060590 2.03 ENST00000652156.1
C9orf57
chromosome 9 open reading frame 57
chr2_+_200440649 1.95 ENST00000366118.2
SPATS2L
spermatogenesis associated serine rich 2 like
chr9_-_72060605 1.86 ENST00000377024.8
ENST00000651200.2
ENST00000652752.1
C9orf57
chromosome 9 open reading frame 57
chr4_-_69760610 1.82 ENST00000310613.8
SULT1B1
sulfotransferase family 1B member 1
chr4_-_158173042 1.77 ENST00000592057.1
ENST00000393807.9
GASK1B
golgi associated kinase 1B
chr10_+_35195843 1.69 ENST00000488741.5
ENST00000474931.5
ENST00000468236.5
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr9_-_41908681 1.62 ENST00000476961.5
CNTNAP3B
contactin associated protein family member 3B
chr2_-_55269038 1.59 ENST00000417363.5
ENST00000412530.1
ENST00000366137.6
ENST00000420637.5
MTIF2
mitochondrial translational initiation factor 2
chr9_-_14300231 1.57 ENST00000636735.1
NFIB
nuclear factor I B
chr12_+_19205294 1.49 ENST00000424268.5
PLEKHA5
pleckstrin homology domain containing A5
chr2_+_108377947 1.49 ENST00000272452.7
SULT1C4
sulfotransferase family 1C member 4
chr4_-_158173004 1.47 ENST00000585682.6
GASK1B
golgi associated kinase 1B
chr3_+_152300135 1.46 ENST00000465907.6
ENST00000492948.5
ENST00000485509.5
ENST00000464596.5
MBNL1
muscleblind like splicing regulator 1
chr2_+_162318884 1.45 ENST00000446271.5
ENST00000429691.6
GCA
grancalcin
chr2_-_156342348 1.43 ENST00000409572.5
NR4A2
nuclear receptor subfamily 4 group A member 2
chr1_+_60865259 1.33 ENST00000371191.5
NFIA
nuclear factor I A
chr1_-_145910031 1.32 ENST00000369304.8
ITGA10
integrin subunit alpha 10
chr3_+_46407558 1.28 ENST00000357392.4
ENST00000400880.3
ENST00000433848.1
CCRL2
C-C motif chemokine receptor like 2
chr1_-_145910066 1.25 ENST00000539363.2
ITGA10
integrin subunit alpha 10
chr21_+_44573724 1.20 ENST00000622352.3
ENST00000400374.4
ENST00000616689.2
KRTAP10-4
keratin associated protein 10-4
chr10_+_92834594 1.15 ENST00000371552.8
EXOC6
exocyst complex component 6
chr12_+_27244222 1.13 ENST00000545470.5
ENST00000389032.8
ENST00000540996.5
STK38L
serine/threonine kinase 38 like
chr12_-_9869345 1.11 ENST00000228438.3
CLEC2B
C-type lectin domain family 2 member B
chr14_-_22819721 1.11 ENST00000554517.5
ENST00000285850.11
ENST00000397529.6
ENST00000555702.5
SLC7A7
solute carrier family 7 member 7
chr10_+_35195124 1.10 ENST00000487763.5
ENST00000473940.5
ENST00000488328.5
ENST00000356917.9
CREM
cAMP responsive element modulator
chrX_+_9912434 1.10 ENST00000418909.6
SHROOM2
shroom family member 2
chr20_+_36214373 1.04 ENST00000432603.1
EPB41L1
erythrocyte membrane protein band 4.1 like 1
chr5_+_141192330 1.02 ENST00000239446.6
PCDHB10
protocadherin beta 10
chr17_+_68525795 0.99 ENST00000592800.5
PRKAR1A
protein kinase cAMP-dependent type I regulatory subunit alpha
chr22_-_37484505 0.95 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr5_+_73813518 0.95 ENST00000296799.8
ARHGEF28
Rho guanine nucleotide exchange factor 28
chr1_+_196819731 0.94 ENST00000320493.10
ENST00000367424.4
CFHR1
complement factor H related 1
chr7_+_93921720 0.91 ENST00000248564.6
GNG11
G protein subunit gamma 11
chr7_+_92057602 0.90 ENST00000491695.2
AKAP9
A-kinase anchoring protein 9
chr7_-_150632333 0.90 ENST00000493969.2
ENST00000328902.9
GIMAP6
GTPase, IMAP family member 6
chr2_+_108378176 0.90 ENST00000409309.3
SULT1C4
sulfotransferase family 1C member 4
chr10_+_5048748 0.90 ENST00000602997.5
ENST00000439082.7
AKR1C3
aldo-keto reductase family 1 member C3
chr3_+_194136138 0.88 ENST00000232424.4
HES1
hes family bHLH transcription factor 1
chr2_-_187554473 0.86 ENST00000453013.5
ENST00000417013.5
TFPI
tissue factor pathway inhibitor
chr2_-_105438503 0.85 ENST00000393352.7
ENST00000607522.1
FHL2
four and a half LIM domains 2
chr7_-_156892987 0.85 ENST00000415428.5
LMBR1
limb development membrane protein 1
chr3_+_183265302 0.84 ENST00000465010.1
B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr5_-_111756245 0.83 ENST00000447165.6
NREP
neuronal regeneration related protein
chr4_-_139280179 0.83 ENST00000398955.2
MGARP
mitochondria localized glutamic acid rich protein
chr11_+_33376077 0.82 ENST00000658780.2
KIAA1549L
KIAA1549 like
chr19_+_49930219 0.82 ENST00000596658.1
ATF5
activating transcription factor 5
chr4_+_89879532 0.78 ENST00000394980.5
MMRN1
multimerin 1
chr17_-_445939 0.78 ENST00000329099.4
RFLNB
refilin B
chr3_+_184812138 0.78 ENST00000287546.8
VPS8
VPS8 subunit of CORVET complex
chr3_+_184812159 0.77 ENST00000625842.3
ENST00000436792.6
ENST00000446204.6
ENST00000422105.5
VPS8
VPS8 subunit of CORVET complex
chr7_+_116222804 0.77 ENST00000393481.6
TES
testin LIM domain protein
chr2_-_187554351 0.77 ENST00000437725.5
ENST00000409676.5
ENST00000233156.9
ENST00000339091.8
ENST00000420747.1
TFPI
tissue factor pathway inhibitor
chr3_-_165837412 0.77 ENST00000479451.5
ENST00000488954.1
ENST00000264381.8
BCHE
butyrylcholinesterase
chr11_+_6876625 0.75 ENST00000379829.2
OR10A4
olfactory receptor family 10 subfamily A member 4
chr5_-_88785493 0.73 ENST00000503554.4
MEF2C
myocyte enhancer factor 2C
chr21_-_26051023 0.73 ENST00000415997.1
APP
amyloid beta precursor protein
chr3_-_114624193 0.68 ENST00000481632.5
ZBTB20
zinc finger and BTB domain containing 20
chr10_+_80413817 0.67 ENST00000372187.9
PRXL2A
peroxiredoxin like 2A
chr14_+_65411845 0.66 ENST00000556518.5
ENST00000557164.5
FUT8
fucosyltransferase 8
chrX_+_139530730 0.66 ENST00000218099.7
F9
coagulation factor IX
chr1_+_196943738 0.66 ENST00000367415.8
ENST00000367421.5
ENST00000649283.1
ENST00000476712.6
ENST00000496448.6
ENST00000473386.1
ENST00000649960.1
CFHR2
complement factor H related 2
chr7_-_64563032 0.66 ENST00000447137.2
ZNF680
zinc finger protein 680
chr9_-_13279407 0.65 ENST00000546205.5
MPDZ
multiple PDZ domain crumbs cell polarity complex component
chr9_-_123268538 0.64 ENST00000360998.3
ENST00000348403.10
STRBP
spermatid perinuclear RNA binding protein
chr16_-_10559135 0.63 ENST00000536829.1
EMP2
epithelial membrane protein 2
chr16_+_22505845 0.62 ENST00000356156.7
NPIPB5
nuclear pore complex interacting protein family member B5
chr19_-_58353482 0.62 ENST00000263100.8
A1BG
alpha-1-B glycoprotein
chr5_-_88823763 0.62 ENST00000635898.1
ENST00000626391.2
ENST00000628656.2
MEF2C
myocyte enhancer factor 2C
chr11_+_73308237 0.62 ENST00000263674.4
ARHGEF17
Rho guanine nucleotide exchange factor 17
chr18_-_55589770 0.61 ENST00000565018.6
ENST00000636400.2
TCF4
transcription factor 4
chr21_-_34526815 0.61 ENST00000492600.1
RCAN1
regulator of calcineurin 1
chr18_-_55589836 0.61 ENST00000537578.5
ENST00000564403.6
TCF4
transcription factor 4
chr9_-_123184233 0.61 ENST00000447404.6
STRBP
spermatid perinuclear RNA binding protein
chr8_+_69492793 0.60 ENST00000616868.1
ENST00000419716.7
ENST00000402687.9
SULF1
sulfatase 1
chr6_+_30888672 0.60 ENST00000446312.5
DDR1
discoidin domain receptor tyrosine kinase 1
chr1_+_84164684 0.58 ENST00000370680.5
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr19_-_54947492 0.58 ENST00000592784.5
ENST00000340844.6
NLRP7
NLR family pyrin domain containing 7
chr14_+_22516273 0.58 ENST00000390510.1
TRAJ27
T cell receptor alpha joining 27
chr2_+_172860038 0.57 ENST00000538974.5
ENST00000540783.5
RAPGEF4
Rap guanine nucleotide exchange factor 4
chr6_+_135851681 0.57 ENST00000308191.11
PDE7B
phosphodiesterase 7B
chr9_-_13279564 0.56 ENST00000541718.5
ENST00000447879.6
MPDZ
multiple PDZ domain crumbs cell polarity complex component
chr6_-_130956371 0.56 ENST00000639623.1
ENST00000525193.5
ENST00000527659.5
EPB41L2
erythrocyte membrane protein band 4.1 like 2
chr3_-_185821092 0.56 ENST00000421047.3
IGF2BP2
insulin like growth factor 2 mRNA binding protein 2
chr2_-_174764407 0.56 ENST00000409219.5
ENST00000409542.5
CHRNA1
cholinergic receptor nicotinic alpha 1 subunit
chr2_-_216372432 0.56 ENST00000273067.5
MARCHF4
membrane associated ring-CH-type finger 4
chr9_-_13279642 0.56 ENST00000319217.12
MPDZ
multiple PDZ domain crumbs cell polarity complex component
chr10_+_5412542 0.56 ENST00000355029.9
NET1
neuroepithelial cell transforming 1
chr2_+_108621260 0.55 ENST00000409441.5
LIMS1
LIM zinc finger domain containing 1
chr18_-_55589795 0.55 ENST00000568740.5
ENST00000629387.2
TCF4
transcription factor 4
chr16_+_22490337 0.55 ENST00000415833.6
NPIPB5
nuclear pore complex interacting protein family member B5
chr5_+_141208697 0.55 ENST00000624949.1
ENST00000622978.1
ENST00000239450.4
PCDHB12
protocadherin beta 12
chr7_+_107583919 0.54 ENST00000491150.5
BCAP29
B cell receptor associated protein 29
chrX_-_100636799 0.54 ENST00000373020.9
TSPAN6
tetraspanin 6
chr6_+_122789197 0.54 ENST00000368440.5
SMPDL3A
sphingomyelin phosphodiesterase acid like 3A
chr2_-_190319845 0.54 ENST00000392332.7
HIBCH
3-hydroxyisobutyryl-CoA hydrolase
chr18_+_7754959 0.51 ENST00000400053.8
PTPRM
protein tyrosine phosphatase receptor type M
chr12_-_122395422 0.51 ENST00000540304.6
CLIP1
CAP-Gly domain containing linker protein 1
chr11_+_121576760 0.50 ENST00000532694.5
ENST00000534286.5
SORL1
sortilin related receptor 1
chr10_+_5446601 0.50 ENST00000449083.5
ENST00000380359.3
NET1
neuroepithelial cell transforming 1
chr1_-_75932392 0.49 ENST00000284142.7
ASB17
ankyrin repeat and SOCS box containing 17
chr8_+_73991345 0.49 ENST00000284818.7
ENST00000518893.1
LY96
lymphocyte antigen 96
chr11_+_844406 0.49 ENST00000397404.5
TSPAN4
tetraspanin 4
chr1_-_179143044 0.49 ENST00000504405.5
ENST00000512653.5
ENST00000344730.7
ABL2
ABL proto-oncogene 2, non-receptor tyrosine kinase
chr15_+_31366138 0.48 ENST00000558844.1
KLF13
Kruppel like factor 13
chr1_-_23868279 0.48 ENST00000374479.4
FUCA1
alpha-L-fucosidase 1
chr3_-_114759115 0.48 ENST00000471418.5
ZBTB20
zinc finger and BTB domain containing 20
chr6_+_156776020 0.47 ENST00000346085.10
ARID1B
AT-rich interaction domain 1B
chr21_-_34526850 0.47 ENST00000481448.5
ENST00000381132.6
RCAN1
regulator of calcineurin 1
chr7_+_135148041 0.45 ENST00000275767.3
TMEM140
transmembrane protein 140
chr1_+_162632454 0.45 ENST00000367921.8
ENST00000367922.7
DDR2
discoidin domain receptor tyrosine kinase 2
chr3_+_136930469 0.45 ENST00000469404.1
ENST00000467911.1
NCK1
NCK adaptor protein 1
chr1_+_213988501 0.44 ENST00000261454.8
ENST00000435016.2
PROX1
prospero homeobox 1
chr2_+_201183120 0.42 ENST00000272879.9
ENST00000286186.11
ENST00000374650.7
ENST00000346817.9
ENST00000313728.11
ENST00000448480.1
CASP10
caspase 10
chr5_+_73626158 0.41 ENST00000296794.10
ENST00000545377.5
ENST00000509848.5
ENST00000513042.7
ARHGEF28
Rho guanine nucleotide exchange factor 28
chr6_+_38715288 0.41 ENST00000327475.11
DNAH8
dynein axonemal heavy chain 8
chr4_+_85475167 0.41 ENST00000503995.5
ARHGAP24
Rho GTPase activating protein 24
chrX_+_10158448 0.41 ENST00000380829.5
ENST00000421085.7
ENST00000674669.1
ENST00000454850.1
CLCN4
chloride voltage-gated channel 4
chr10_+_114938187 0.40 ENST00000298746.5
TRUB1
TruB pseudouridine synthase family member 1
chr9_-_20382461 0.40 ENST00000380321.5
ENST00000629733.3
MLLT3
MLLT3 super elongation complex subunit
chr1_+_63523490 0.40 ENST00000371088.5
EFCAB7
EF-hand calcium binding domain 7
chr5_+_141199555 0.40 ENST00000624887.1
ENST00000354757.5
PCDHB11
protocadherin beta 11
chr11_+_7088991 0.40 ENST00000306904.7
RBMXL2
RBMX like 2
chr2_+_172928165 0.40 ENST00000535187.5
RAPGEF4
Rap guanine nucleotide exchange factor 4
chr4_+_85827745 0.40 ENST00000509300.5
ARHGAP24
Rho GTPase activating protein 24
chr17_-_48613468 0.39 ENST00000498634.2
HOXB8
homeobox B8
chr4_+_85827891 0.39 ENST00000514229.5
ARHGAP24
Rho GTPase activating protein 24
chr7_+_143288215 0.39 ENST00000619992.4
ENST00000310447.10
CASP2
caspase 2
chr13_-_77919390 0.39 ENST00000475537.2
ENST00000646605.1
EDNRB
endothelin receptor type B
chr18_+_63777773 0.39 ENST00000447428.5
ENST00000546027.5
SERPINB7
serpin family B member 7
chr12_-_102197827 0.39 ENST00000329406.5
PMCH
pro-melanin concentrating hormone
chr20_-_63956382 0.39 ENST00000358711.7
ENST00000354216.11
UCKL1
uridine-cytidine kinase 1 like 1
chr3_+_159273235 0.38 ENST00000638749.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr17_+_35844077 0.38 ENST00000604694.1
TAF15
TATA-box binding protein associated factor 15
chr20_-_61998132 0.38 ENST00000474089.5
TAF4
TATA-box binding protein associated factor 4
chr12_-_10388976 0.37 ENST00000540818.5
KLRK1
killer cell lectin like receptor K1
chr7_+_80638662 0.37 ENST00000394788.7
CD36
CD36 molecule
chr2_-_174764436 0.37 ENST00000409323.1
ENST00000261007.9
ENST00000348749.9
ENST00000672640.1
CHRNA1
cholinergic receptor nicotinic alpha 1 subunit
chr1_-_93614091 0.37 ENST00000370247.7
BCAR3
BCAR3 adaptor protein, NSP family member
chr12_-_47079859 0.37 ENST00000266581.4
AMIGO2
adhesion molecule with Ig like domain 2
chrX_+_106611930 0.36 ENST00000372544.6
ENST00000372548.9
RADX
RPA1 related single stranded DNA binding protein, X-linked
chr14_+_30577752 0.36 ENST00000547532.5
ENST00000555429.1
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr4_-_110198579 0.36 ENST00000302274.8
ELOVL6
ELOVL fatty acid elongase 6
chr8_+_74339566 0.36 ENST00000675376.1
GDAP1
ganglioside induced differentiation associated protein 1
chr18_-_12656716 0.36 ENST00000462226.1
ENST00000497844.6
ENST00000309836.9
ENST00000453447.6
SPIRE1
spire type actin nucleation factor 1
chr1_-_216805367 0.36 ENST00000360012.7
ESRRG
estrogen related receptor gamma
chr3_-_134250831 0.36 ENST00000623711.4
RYK
receptor like tyrosine kinase
chr9_-_96383675 0.35 ENST00000375257.2
ENST00000375259.9
ENST00000253270.13
SLC35D2
solute carrier family 35 member D2
chr1_+_220748297 0.34 ENST00000366913.8
MTARC2
mitochondrial amidoxime reducing component 2
chr6_+_87472925 0.34 ENST00000369556.7
ENST00000369557.9
ENST00000369552.9
SLC35A1
solute carrier family 35 member A1
chr3_+_172754457 0.34 ENST00000441497.6
ECT2
epithelial cell transforming 2
chr1_-_53940100 0.34 ENST00000371376.1
HSPB11
heat shock protein family B (small) member 11
chr10_+_68560317 0.34 ENST00000373644.5
TET1
tet methylcytosine dioxygenase 1
chr7_-_156893150 0.33 ENST00000353442.10
LMBR1
limb development membrane protein 1
chr4_-_110198650 0.33 ENST00000394607.7
ELOVL6
ELOVL fatty acid elongase 6
chr6_+_41637005 0.33 ENST00000419164.6
ENST00000373051.6
MDFI
MyoD family inhibitor
chr10_+_21524627 0.33 ENST00000651097.1
MLLT10
MLLT10 histone lysine methyltransferase DOT1L cofactor
chr7_-_139716980 0.33 ENST00000342645.7
HIPK2
homeodomain interacting protein kinase 2
chr15_-_55365231 0.32 ENST00000568543.1
CCPG1
cell cycle progression 1
chr11_+_65027402 0.32 ENST00000377244.8
ENST00000534637.5
ENST00000524831.5
SNX15
sorting nexin 15
chr17_+_30970984 0.32 ENST00000443677.6
ENST00000324689.8
ENST00000328381.10
ENST00000535306.6
ENST00000580444.2
RNF135
ring finger protein 135
chr11_+_112175526 0.32 ENST00000532612.5
ENST00000438022.5
BCO2
beta-carotene oxygenase 2
chr3_+_107377433 0.31 ENST00000261058.3
CCDC54
coiled-coil domain containing 54
chr10_+_70404129 0.31 ENST00000373218.5
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr12_-_8650529 0.31 ENST00000543467.5
MFAP5
microfibril associated protein 5
chr15_+_41256907 0.31 ENST00000560965.1
CHP1
calcineurin like EF-hand protein 1
chr4_-_139302460 0.31 ENST00000394223.2
ENST00000676245.1
NDUFC1
NADH:ubiquinone oxidoreductase subunit C1
chr10_+_21524670 0.30 ENST00000631589.1
MLLT10
MLLT10 histone lysine methyltransferase DOT1L cofactor
chr17_+_19282979 0.30 ENST00000395626.5
ENST00000571254.1
EPN2
epsin 2
chr14_-_106639589 0.30 ENST00000390630.3
IGHV4-61
immunoglobulin heavy variable 4-61
chr18_-_33136075 0.30 ENST00000581852.5
CCDC178
coiled-coil domain containing 178
chr2_-_8837589 0.29 ENST00000319688.5
ENST00000489024.5
ENST00000256707.8
ENST00000473731.5
KIDINS220
kinase D interacting substrate 220
chr1_+_95151377 0.29 ENST00000604203.1
TLCD4-RWDD3
TLCD4-RWDD3 readthrough
chr4_+_39182497 0.28 ENST00000509560.5
ENST00000512112.5
ENST00000399820.8
ENST00000506503.1
WDR19
WD repeat domain 19
chr19_-_9219589 0.28 ENST00000641244.1
ENST00000641669.1
OR7D4
olfactory receptor family 7 subfamily D member 4
chr6_+_116369837 0.27 ENST00000645988.1
DSE
dermatan sulfate epimerase
chr11_-_107457801 0.27 ENST00000282251.9
CWF19L2
CWF19 like cell cycle control factor 2
chr7_+_1688119 0.27 ENST00000424383.4
ELFN1
extracellular leucine rich repeat and fibronectin type III domain containing 1
chr6_+_42929127 0.26 ENST00000394142.7
CNPY3
canopy FGF signaling regulator 3
chr1_+_151766655 0.26 ENST00000400999.7
OAZ3
ornithine decarboxylase antizyme 3
chr5_+_55853464 0.26 ENST00000652039.1
IL31RA
interleukin 31 receptor A
chr11_+_6926417 0.26 ENST00000610573.4
ENST00000278319.10
ZNF215
zinc finger protein 215
chr5_+_119476530 0.26 ENST00000645099.1
ENST00000513628.5
HSD17B4
hydroxysteroid 17-beta dehydrogenase 4
chr7_+_134843884 0.25 ENST00000445569.6
CALD1
caldesmon 1
chr18_-_24272179 0.25 ENST00000399443.7
OSBPL1A
oxysterol binding protein like 1A
chr2_+_206275002 0.25 ENST00000650097.1
ENST00000649525.1
ENST00000649998.1
ZDBF2
zinc finger DBF-type containing 2
chr15_+_42404842 0.25 ENST00000673928.1
CAPN3
calpain 3
chr2_+_234050679 0.25 ENST00000373368.5
ENST00000168148.8
SPP2
secreted phosphoprotein 2
chr12_-_120325936 0.25 ENST00000549767.1
PLA2G1B
phospholipase A2 group IB
chr6_-_116829037 0.24 ENST00000368549.7
ENST00000530250.1
ENST00000310357.8
GPRC6A
G protein-coupled receptor class C group 6 member A
chr11_+_112176364 0.24 ENST00000526088.5
ENST00000532593.5
ENST00000531169.5
BCO2
beta-carotene oxygenase 2
chr5_+_141245384 0.24 ENST00000623671.1
ENST00000231173.6
PCDHB15
protocadherin beta 15
chr2_-_144517663 0.23 ENST00000427902.5
ENST00000462355.2
ENST00000470879.5
ENST00000409487.7
ENST00000435831.5
ENST00000630572.2
ZEB2
zinc finger E-box binding homeobox 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.7 GO:0097338 response to clozapine(GO:0097338)
0.5 1.6 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.5 1.4 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.4 0.8 GO:0014016 neuroblast differentiation(GO:0014016)
0.3 0.9 GO:0006714 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.3 0.9 GO:0021558 trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164) negative regulation of pro-B cell differentiation(GO:2000974)
0.3 0.8 GO:0061182 negative regulation of chondrocyte development(GO:0061182)
0.3 6.5 GO:0006068 ethanol catabolic process(GO:0006068)
0.3 2.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 0.7 GO:0036071 N-glycan fucosylation(GO:0036071)
0.2 0.8 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.2 0.6 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 0.6 GO:0046247 tetraterpenoid metabolic process(GO:0016108) carotenoid metabolic process(GO:0016116) carotene catabolic process(GO:0016121) xanthophyll metabolic process(GO:0016122) terpene catabolic process(GO:0046247)
0.2 1.3 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.2 0.5 GO:1902769 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.2 0.8 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.2 1.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 0.4 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.1 0.4 GO:0002194 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 1.6 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 4.5 GO:0072189 ureter development(GO:0072189)
0.1 0.4 GO:0001554 luteolysis(GO:0001554)
0.1 1.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.5 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.4 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.1 0.7 GO:0071874 microglia differentiation(GO:0014004) microglia development(GO:0014005) collateral sprouting in absence of injury(GO:0048669) smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.6 GO:0035645 posterior midgut development(GO:0007497) enteric smooth muscle cell differentiation(GO:0035645)
0.1 0.9 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 3.9 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.5 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.5 GO:0006574 valine catabolic process(GO:0006574)
0.1 0.4 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.1 0.3 GO:0015847 putrescine transport(GO:0015847)
0.1 0.3 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.1 1.1 GO:0045176 apical protein localization(GO:0045176)
0.1 0.4 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.3 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.1 0.4 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.1 0.2 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.2 GO:0000964 mitochondrial RNA 5'-end processing(GO:0000964)
0.1 0.2 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 0.6 GO:0070836 caveola assembly(GO:0070836)
0.1 0.5 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 0.9 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 0.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 1.0 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.2 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.7 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.0 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.5 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.1 0.4 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.7 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.1 0.2 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.3 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 0.8 GO:0051451 myoblast migration(GO:0051451)
0.1 0.1 GO:1990535 neuron projection maintenance(GO:1990535)
0.1 0.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.8 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.2 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 3.2 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.4 GO:0044211 CTP salvage(GO:0044211)
0.0 0.5 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0050787 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
0.0 0.1 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 0.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.2 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.0 0.4 GO:0072564 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.5 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.2 GO:1990637 response to prolactin(GO:1990637)
0.0 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.4 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.6 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.3 GO:0030578 PML body organization(GO:0030578)
0.0 0.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.2 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.2 GO:0009624 response to nematode(GO:0009624)
0.0 0.1 GO:0060723 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 1.1 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.3 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.0 0.2 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 1.3 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.4 GO:2000096 segment specification(GO:0007379) positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.0 0.6 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.2 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.2 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.1 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.1 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.0 0.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.4 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 1.0 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 1.0 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.3 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.1 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.0 0.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.3 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.4 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.2 GO:0051026 chiasma assembly(GO:0051026)
0.0 1.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.5 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0032700 negative regulation of interleukin-17 production(GO:0032700)
0.0 0.1 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 1.2 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.1 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.3 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.2 GO:0046689 response to mercury ion(GO:0046689)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.3 GO:0043031 T-helper 2 cell cytokine production(GO:0035745) negative regulation of macrophage activation(GO:0043031)
0.0 0.2 GO:0045008 depyrimidination(GO:0045008)
0.0 0.2 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 1.3 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 1.5 GO:0032091 negative regulation of protein binding(GO:0032091)
0.0 0.6 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.0 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 1.0 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 1.3 GO:0035113 embryonic limb morphogenesis(GO:0030326) embryonic appendage morphogenesis(GO:0035113)
0.0 0.2 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.9 GO:0032760 positive regulation of tumor necrosis factor production(GO:0032760)
0.0 0.2 GO:0015866 ADP transport(GO:0015866)
0.0 0.0 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.1 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.0 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.5 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 1.7 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.6 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.3 1.5 GO:0033263 CORVET complex(GO:0033263)
0.3 6.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 0.9 GO:0044307 dendritic branch(GO:0044307)
0.1 2.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 1.8 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.1 0.2 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.1 1.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.3 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.5 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.2 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.5 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 1.2 GO:0000145 exocyst(GO:0000145)
0.0 1.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.6 GO:0008091 spectrin(GO:0008091)
0.0 0.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 1.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 4.1 GO:0030018 Z disc(GO:0030018)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.5 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 1.5 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 1.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.2 GO:0032982 myosin filament(GO:0032982)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0030914 STAGA complex(GO:0030914)
0.0 5.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.3 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0001069 regulatory region RNA binding(GO:0001069)
0.4 5.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.3 6.5 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.3 2.6 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.3 0.9 GO:0047787 geranylgeranyl reductase activity(GO:0045550) delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.3 0.8 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.2 1.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 0.7 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.2 0.8 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.2 0.5 GO:0003860 3-hydroxyisobutyryl-CoA hydrolase activity(GO:0003860)
0.2 1.0 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.2 2.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 4.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.3 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.3 GO:0015489 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.1 1.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 1.6 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.3 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.1 0.6 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 1.8 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.8 GO:0051425 PTB domain binding(GO:0051425)
0.1 1.3 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.4 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 0.7 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 1.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.3 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 1.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.7 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.5 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 1.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.0 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.6 GO:0042731 PH domain binding(GO:0042731)
0.0 0.2 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.2 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.4 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.2 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 1.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.4 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.4 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.2 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.4 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.9 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.3 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 1.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.9 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.7 GO:0031005 filamin binding(GO:0031005)
0.0 0.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 1.0 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.0 GO:0055100 adiponectin binding(GO:0055100)
0.0 0.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.0 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 2.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.4 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.4 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.9 PID IL3 PATHWAY IL3-mediated signaling events
0.1 3.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 6.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 4.3 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.9 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.5 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 2.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.7 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.8 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.9 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.6 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.4 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 6.7 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 0.5 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.9 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 1.9 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 1.5 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.7 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 1.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 2.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.0 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.0 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 1.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.7 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.9 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 1.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.7 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 2.3 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 1.0 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.0 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 1.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.1 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction