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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for FUBP1

Z-value: 0.80

Motif logo

Transcription factors associated with FUBP1

Gene Symbol Gene ID Gene Info
ENSG00000162613.17 FUBP1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FUBP1hg38_v1_chr1_-_77979054_77979116-0.404.8e-02Click!

Activity profile of FUBP1 motif

Sorted Z-values of FUBP1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FUBP1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr4_-_16898619 3.68 ENST00000502640.5
ENST00000304523.10
ENST00000506732.1
LIM domain binding 2
chr4_-_16898561 3.28 ENST00000515064.5
ENST00000441778.6
LIM domain binding 2
chr3_-_149333407 3.15 ENST00000470080.5
transmembrane 4 L six family member 18
chr11_-_33869816 3.06 ENST00000395833.7
LIM domain only 2
chr3_-_149333619 2.97 ENST00000296059.7
transmembrane 4 L six family member 18
chr4_-_100517991 2.93 ENST00000511970.5
ENST00000502569.1
ENST00000305864.7
ENST00000296420.9
endomucin
chr1_+_84144260 2.63 ENST00000370685.7
protein kinase cAMP-activated catalytic subunit beta
chr3_+_40100007 1.99 ENST00000539167.2
myosin VIIA and Rab interacting protein
chr5_-_88883147 1.98 ENST00000513252.5
ENST00000506554.5
ENST00000508569.5
ENST00000637732.1
ENST00000504921.7
ENST00000637481.1
ENST00000510942.5
myocyte enhancer factor 2C
chr1_+_108560031 1.87 ENST00000405454.1
ENST00000370035.8
family with sequence similarity 102 member B
chr18_-_55588535 1.79 ENST00000566286.5
ENST00000566279.5
ENST00000626595.2
ENST00000564999.5
ENST00000616053.4
ENST00000356073.8
transcription factor 4
chr14_+_61187544 1.79 ENST00000555185.5
ENST00000557294.5
ENST00000556778.5
protein kinase C eta
chr4_-_88231322 1.77 ENST00000515655.5
ATP binding cassette subfamily G member 2 (Junior blood group)
chr2_-_182427014 1.55 ENST00000409365.5
ENST00000351439.9
phosphodiesterase 1A
chr12_-_9869345 1.37 ENST00000228438.3
C-type lectin domain family 2 member B
chr3_-_187736493 1.30 ENST00000232014.8
BCL6 transcription repressor
chr5_-_88883199 1.29 ENST00000514015.5
ENST00000503075.1
myocyte enhancer factor 2C
chr12_-_85836372 1.25 ENST00000361228.5
Ras association domain family member 9
chr12_+_48119787 1.18 ENST00000551804.5
phosphofructokinase, muscle
chr2_+_33134620 1.17 ENST00000402934.5
ENST00000404525.5
ENST00000407925.5
latent transforming growth factor beta binding protein 1
chr2_+_33134579 1.17 ENST00000418533.6
latent transforming growth factor beta binding protein 1
chr4_-_151226427 1.13 ENST00000304527.8
ENST00000409598.8
SH3 domain containing 19
chr14_+_65411845 1.06 ENST00000556518.5
ENST00000557164.5
fucosyltransferase 8
chr1_+_43300971 1.04 ENST00000372476.8
ENST00000538015.1
tyrosine kinase with immunoglobulin like and EGF like domains 1
chr17_+_69502397 0.98 ENST00000613873.4
ENST00000589647.5
mitogen-activated protein kinase kinase 6
chr17_-_64390852 0.87 ENST00000563924.6
platelet and endothelial cell adhesion molecule 1
chr12_+_10212867 0.86 ENST00000545047.5
ENST00000266458.10
ENST00000629504.1
ENST00000543602.5
ENST00000545887.1
GABA type A receptor associated protein like 1
chr18_-_55588184 0.84 ENST00000354452.8
ENST00000565908.6
ENST00000635822.2
transcription factor 4
chr19_-_54941610 0.80 ENST00000328092.9
ENST00000590030.5
NLR family pyrin domain containing 7
chr4_-_25863537 0.78 ENST00000502949.5
ENST00000264868.9
ENST00000513691.1
ENST00000514872.1
SEL1L family member 3
chr10_+_61901678 0.76 ENST00000644638.1
ENST00000681100.1
ENST00000279873.12
AT-rich interaction domain 5B
chr20_+_21125981 0.76 ENST00000619574.4
kizuna centrosomal protein
chr22_-_28741783 0.75 ENST00000439200.5
ENST00000405598.5
ENST00000398017.3
ENST00000649563.1
ENST00000650281.1
ENST00000425190.7
ENST00000404276.6
ENST00000650233.1
ENST00000348295.7
ENST00000382580.6
checkpoint kinase 2
chr1_+_77918128 0.75 ENST00000342754.5
nexilin F-actin binding protein
chr19_+_44751251 0.74 ENST00000444487.1
BCL3 transcription coactivator
chr20_+_21126074 0.74 ENST00000619189.5
kizuna centrosomal protein
chr6_-_36757380 0.72 ENST00000393189.2
copine 5
chr1_-_243843226 0.70 ENST00000336199.9
AKT serine/threonine kinase 3
chr10_-_63269057 0.70 ENST00000542921.5
jumonji domain containing 1C
chr6_+_118894144 0.69 ENST00000229595.6
anti-silencing function 1A histone chaperone
chr2_-_151261839 0.69 ENST00000331426.6
RNA binding motif protein 43
chr2_+_201116143 0.66 ENST00000443227.5
ENST00000309955.8
ENST00000341222.10
ENST00000341582.10
CASP8 and FADD like apoptosis regulator
chr2_+_66435558 0.65 ENST00000488550.5
Meis homeobox 1
chr6_+_5260992 0.59 ENST00000324331.10
phenylalanyl-tRNA synthetase 2, mitochondrial
chr4_-_151227881 0.57 ENST00000652233.1
ENST00000514152.5
SH3 domain containing 19
chr4_+_169660062 0.56 ENST00000507875.5
ENST00000613795.4
chloride voltage-gated channel 3
chr7_-_15561986 0.55 ENST00000342526.8
alkylglycerol monooxygenase
chr14_-_21383989 0.55 ENST00000216297.7
SPT16 homolog, facilitates chromatin remodeling subunit
chr15_-_55365231 0.52 ENST00000568543.1
cell cycle progression 1
chr21_-_37072688 0.52 ENST00000464265.5
ENST00000399102.5
phosphatidylinositol glycan anchor biosynthesis class P
chr9_+_125748175 0.51 ENST00000491787.7
ENST00000447726.6
PBX homeobox 3
chr20_-_17558811 0.51 ENST00000536626.7
ENST00000377868.6
beaded filament structural protein 1
chr1_-_243843164 0.46 ENST00000491219.6
ENST00000680056.1
ENST00000492957.2
AKT serine/threonine kinase 3
chr18_+_7754959 0.46 ENST00000400053.8
protein tyrosine phosphatase receptor type M
chr11_+_114060204 0.45 ENST00000683318.1
zinc finger and BTB domain containing 16
chr19_-_14090963 0.45 ENST00000269724.5
sterile alpha motif domain containing 1
chr22_-_40856565 0.43 ENST00000620312.4
ENST00000216218.8
ST13 Hsp70 interacting protein
chr2_-_65366650 0.42 ENST00000443619.6
sprouty related EVH1 domain containing 2
chr19_-_49362376 0.40 ENST00000601519.5
ENST00000593945.6
ENST00000539846.5
ENST00000596757.1
ENST00000311227.6
TEA domain transcription factor 2
chr19_+_15944299 0.40 ENST00000641275.1
olfactory receptor family 10 subfamily H member 4
chr7_+_56064224 0.39 ENST00000651354.1
ENST00000651586.1
ENST00000652303.1
ENST00000275607.13
ENST00000650735.1
ENST00000395435.7
ENST00000413952.7
ENST00000342190.11
ENST00000437307.6
ENST00000434526.8
ENST00000413756.5
ENST00000451338.1
sulfatase modifying factor 2
chr7_+_80638633 0.39 ENST00000447544.7
ENST00000482059.6
CD36 molecule
chr7_+_80638510 0.38 ENST00000433696.6
ENST00000538969.5
ENST00000544133.5
CD36 molecule
chr10_+_99782628 0.37 ENST00000648689.1
ENST00000647814.1
ATP binding cassette subfamily C member 2
chr5_+_140647802 0.37 ENST00000417647.7
ENST00000507593.5
ENST00000508301.5
IK cytokine
chr12_-_8650529 0.37 ENST00000543467.5
microfibril associated protein 5
chr9_-_70869076 0.37 ENST00000677594.1
transient receptor potential cation channel subfamily M member 3
chr2_+_176151543 0.36 ENST00000306324.4
homeobox D4
chr1_-_154936681 0.35 ENST00000368467.4
phosphomevalonate kinase
chr12_+_12717359 0.34 ENST00000614874.2
ENST00000228872.9
cyclin dependent kinase inhibitor 1B
chr15_-_29822418 0.34 ENST00000614355.5
ENST00000495972.6
ENST00000346128.10
tight junction protein 1
chr2_-_197675578 0.34 ENST00000295049.9
raftlin family member 2
chr4_+_88523810 0.33 ENST00000512194.2
ENST00000598772.1
ENST00000597259.2
HECT and RLD domain containing E3 ubiquitin protein ligase 3
PIGY divergent transcript
chr1_-_17045219 0.32 ENST00000491274.5
succinate dehydrogenase complex iron sulfur subunit B
chr6_+_32164586 0.31 ENST00000333845.11
ENST00000395512.5
ENST00000432129.1
EGF like domain multiple 8
chr3_+_57890011 0.30 ENST00000494088.6
ENST00000438794.5
sarcolemma associated protein
chr8_+_74320613 0.30 ENST00000675821.1
ganglioside induced differentiation associated protein 1
chr21_-_37073019 0.30 ENST00000360525.9
phosphatidylinositol glycan anchor biosynthesis class P
chr5_+_76403266 0.28 ENST00000274364.11
IQ motif containing GTPase activating protein 2
chr12_+_18262730 0.28 ENST00000675017.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr14_+_88594395 0.27 ENST00000318308.10
zinc finger CCCH-type containing 14
chr19_-_55166565 0.27 ENST00000526003.5
ENST00000534170.5
ENST00000524407.7
dynein axonemal assembly factor 3
chr2_+_201257980 0.27 ENST00000447616.5
ENST00000358485.8
ENST00000392266.7
caspase 8
chr1_+_15456727 0.26 ENST00000359621.5
chymotrypsin like elastase 2A
chr14_+_101809795 0.26 ENST00000350249.7
ENST00000557621.5
ENST00000556946.1
protein phosphatase 2 regulatory subunit B'gamma
chrX_+_51893533 0.25 ENST00000375722.5
ENST00000326587.12
ENST00000375695.2
MAGE family member D1
chr19_-_55166632 0.25 ENST00000532817.5
ENST00000527223.6
ENST00000391720.8
dynein axonemal assembly factor 3
chr4_-_119300546 0.25 ENST00000504110.2
chromosome 4 open reading frame 3
chr22_-_36703723 0.25 ENST00000300105.7
calcium voltage-gated channel auxiliary subunit gamma 2
chr4_-_83284752 0.24 ENST00000311461.7
ENST00000647002.2
ENST00000311469.9
coenzyme Q2, polyprenyltransferase
chr14_+_101809855 0.24 ENST00000557714.1
ENST00000445439.7
ENST00000334743.9
ENST00000557095.5
protein phosphatase 2 regulatory subunit B'gamma
chr6_-_111567271 0.23 ENST00000464903.1
ENST00000368730.5
ENST00000368735.1
TRAF3 interacting protein 2
chr10_-_68332914 0.23 ENST00000358769.7
ENST00000495025.2
phenazine biosynthesis like protein domain containing
chr15_+_49170200 0.23 ENST00000396509.6
galactokinase 2
chr1_+_176463164 0.23 ENST00000367661.7
ENST00000367662.5
pappalysin 2
chr12_+_15956585 0.23 ENST00000526530.1
deoxyribose-phosphate aldolase
chr11_-_790062 0.22 ENST00000330106.5
cell cycle exit and neuronal differentiation 1
chr4_+_173370908 0.21 ENST00000296504.4
Sin3A associated protein 30
chrX_+_41447322 0.20 ENST00000378220.2
ENST00000342595.2
nyctalopin
chr1_-_44674402 0.20 ENST00000420706.1
ENST00000372235.7
ENST00000372242.7
ENST00000372243.7
ENST00000372244.3
ENST00000372237.8
transmembrane protein 53
chr11_-_118225002 0.19 ENST00000356289.10
ENST00000526620.5
junction adhesion molecule like
chr3_+_130560334 0.19 ENST00000358511.10
collagen type VI alpha 6 chain
chr11_+_1853049 0.18 ENST00000311604.8
lymphocyte specific protein 1
chr14_+_69191760 0.17 ENST00000409949.5
ENST00000312994.9
ENST00000409242.5
ENST00000413191.1
exonuclease 3'-5' domain containing 2
chr11_+_75562274 0.17 ENST00000532356.5
ENST00000524558.5
serpin family H member 1
chr9_-_27005659 0.17 ENST00000380055.6
leucine rich repeat containing 19
chrX_+_103330206 0.16 ENST00000372666.1
ENST00000332431.5
transcription elongation factor A like 7
chr2_+_180981108 0.16 ENST00000602710.5
ubiquitin conjugating enzyme E2 E3
chr11_+_57763820 0.16 ENST00000674106.1
catenin delta 1
chr13_-_26221703 0.15 ENST00000381570.7
ENST00000346166.7
ring finger protein 6
chr18_-_63318674 0.15 ENST00000589955.2
BCL2 apoptosis regulator
chr11_+_75562242 0.15 ENST00000526397.5
ENST00000529643.1
ENST00000525492.5
ENST00000530284.5
ENST00000358171.8
serpin family H member 1
chr19_+_13023958 0.14 ENST00000587760.5
ENST00000585575.5
nuclear factor I X
chr6_+_167111789 0.14 ENST00000400926.5
C-C motif chemokine receptor 6
chr7_+_75092573 0.14 ENST00000651028.1
ENST00000472837.7
ENST00000629105.2
ENST00000619142.4
ENST00000614064.4
GTF2I repeat domain containing 2B
chr19_-_45493208 0.14 ENST00000430715.6
reticulon 2
chr4_+_183683849 0.13 ENST00000512476.1
trafficking protein particle complex 11
chrX_+_12906639 0.13 ENST00000311912.5
toll like receptor 8
chr19_-_44304968 0.13 ENST00000591609.1
ENST00000589799.5
ENST00000291182.9
ENST00000650576.1
ENST00000589248.5
zinc finger protein 235
chr5_+_137889437 0.12 ENST00000508638.5
ENST00000508883.6
ENST00000502810.5
polycystin 2 like 2, transient receptor potential cation channel
chr1_-_216805367 0.12 ENST00000360012.7
estrogen related receptor gamma
chr4_-_88823165 0.12 ENST00000508369.5
family with sequence similarity 13 member A
chr16_+_28553908 0.12 ENST00000317058.8
SAGA complex associated factor 29
chr19_+_18571730 0.11 ENST00000596304.5
ENST00000430157.6
ENST00000596273.5
ENST00000442744.7
ENST00000595683.5
ENST00000599256.5
ENST00000595158.5
ENST00000598780.5
ubiquitin A-52 residue ribosomal protein fusion product 1
chr22_-_46263338 0.11 ENST00000253255.7
polycystin family receptor for egg jelly
chr9_-_107489754 0.11 ENST00000610832.1
ENST00000374672.5
Kruppel like factor 4
chr11_+_99020940 0.10 ENST00000524871.6
contactin 5
chr15_+_80072559 0.10 ENST00000560228.5
ENST00000559835.5
ENST00000559775.5
ENST00000558688.5
ENST00000560392.5
ENST00000560976.5
ENST00000558272.5
ENST00000558390.5
zinc finger AN1-type containing 6
chr2_-_10812706 0.10 ENST00000272227.8
protein disulfide isomerase family A member 6
chr9_-_96418334 0.09 ENST00000375256.5
zinc finger protein 367
chr17_-_15566276 0.09 ENST00000630868.1
CMT1A duplicated region transcript 1
chr19_+_19192229 0.08 ENST00000421262.7
ENST00000456252.7
ENST00000303088.9
ENST00000593273.5
regulatory factor X associated ankyrin containing protein
chr10_-_54801221 0.08 ENST00000644397.2
ENST00000395445.6
ENST00000613657.5
ENST00000320301.11
protocadherin related 15
chrX_-_33128360 0.08 ENST00000378677.6
dystrophin
chr8_-_42377227 0.07 ENST00000220812.3
dickkopf WNT signaling pathway inhibitor 4
chr19_+_1438351 0.07 ENST00000233609.8
ribosomal protein S15
chr10_-_54801179 0.07 ENST00000373955.5
protocadherin related 15
chr13_+_48976597 0.06 ENST00000541916.5
fibronectin type III domain containing 3A
chr17_+_58083407 0.06 ENST00000579991.3
dynein light chain LC8-type 2
chr10_+_119819244 0.06 ENST00000637174.1
inositol polyphosphate-5-phosphatase F
chr4_+_47485268 0.05 ENST00000273859.8
ENST00000504445.1
ATPase phospholipid transporting 10D (putative)
chr13_+_36432487 0.05 ENST00000255465.7
ENST00000625767.1
cyclin A1
chr7_+_54542300 0.05 ENST00000302287.7
ENST00000407838.7
V-set and transmembrane domain containing 2A
chr10_-_54801262 0.04 ENST00000373965.6
ENST00000616114.4
ENST00000621708.4
ENST00000495484.5
ENST00000395440.5
ENST00000395442.5
ENST00000617271.4
ENST00000395446.5
ENST00000409834.5
ENST00000361849.7
ENST00000373957.7
ENST00000395430.5
ENST00000395433.5
ENST00000437009.5
protocadherin related 15
chrX_+_12906612 0.04 ENST00000218032.7
toll like receptor 8
chr1_-_155301423 0.04 ENST00000342741.6
pyruvate kinase L/R
chr5_+_137889469 0.04 ENST00000290431.5
polycystin 2 like 2, transient receptor potential cation channel
chr1_+_202348727 0.04 ENST00000356764.6
protein phosphatase 1 regulatory subunit 12B
chr19_+_54105923 0.03 ENST00000420296.1
NADH:ubiquinone oxidoreductase subunit A3
chr12_-_91058016 0.03 ENST00000266719.4
keratocan
chr2_-_287687 0.03 ENST00000401489.6
ENST00000619265.4
ALK and LTK ligand 2
chr3_+_148827800 0.03 ENST00000282957.9
ENST00000468341.1
carboxypeptidase B1
chr2_-_168890368 0.03 ENST00000282074.7
SPC25 component of NDC80 kinetochore complex
chr2_-_287299 0.02 ENST00000405290.5
ALK and LTK ligand 2
chr12_-_91182784 0.02 ENST00000547568.6
ENST00000052754.10
ENST00000552962.5
decorin
chr21_+_43789522 0.01 ENST00000497547.2
ribosomal RNA processing 1
chr3_-_120285215 0.01 ENST00000464295.6
G protein-coupled receptor 156
chr11_-_111871271 0.01 ENST00000398006.6
ALG9 alpha-1,2-mannosyltransferase
chr15_+_49170237 0.00 ENST00000560031.6
ENST00000558145.5
ENST00000544523.5
ENST00000560138.5
galactokinase 2
chr6_+_29111560 0.00 ENST00000377169.2
olfactory receptor family 2 subfamily J member 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.3 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.4 2.6 GO:0097338 response to clozapine(GO:0097338)
0.4 1.1 GO:0036071 N-glycan fucosylation(GO:0036071)
0.3 2.1 GO:1903464 negative regulation of mitotic cell cycle DNA replication(GO:1903464)
0.3 1.0 GO:0072709 cellular response to sorbitol(GO:0072709)
0.3 2.3 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 0.7 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.2 1.2 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.2 0.9 GO:0072011 diapedesis(GO:0050904) glomerular endothelium development(GO:0072011)
0.2 7.2 GO:0010669 epithelial structure maintenance(GO:0010669)
0.2 1.8 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.1 1.8 GO:0015886 heme transport(GO:0015886)
0.1 2.0 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 0.4 GO:0050787 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
0.1 0.4 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 3.1 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1 0.6 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.5 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.6 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.4 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.1 0.8 GO:0070543 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.6 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.4 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.1 0.3 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.1 1.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.3 GO:0039513 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.1 1.7 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 1.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.7 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.5 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.9 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.3 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.2 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.8 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.2 GO:0021699 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0 0.2 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.2 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.1 GO:0014740 mesodermal cell fate determination(GO:0007500) negative regulation of muscle hyperplasia(GO:0014740)
0.0 0.3 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0 0.7 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.8 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.6 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.2 GO:0035696 monocyte extravasation(GO:0035696)
0.0 0.3 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.5 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.8 GO:0016577 histone demethylation(GO:0016577)
0.0 0.2 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.4 GO:0030903 notochord development(GO:0030903)
0.0 0.1 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 0.4 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 1.0 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.6 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.3 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.3 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.1 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.0 0.6 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.5 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.1 GO:0070352 positive regulation of white fat cell proliferation(GO:0070352)
0.0 0.5 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.3 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.2 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.3 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 0.7 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 2.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 2.7 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.4 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 2.0 GO:0031045 dense core granule(GO:0031045)
0.1 0.8 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.3 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 1.2 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.9 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 1.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 12.7 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.9 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 1.2 GO:0005657 replication fork(GO:0005657)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.0 GO:0030274 LIM domain binding(GO:0030274)
0.5 2.3 GO:0050436 microfibril binding(GO:0050436)
0.4 1.1 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.3 1.8 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.3 1.6 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 3.3 GO:0003680 AT DNA binding(GO:0003680)
0.2 2.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 1.8 GO:0015232 heme transporter activity(GO:0015232)
0.1 1.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.6 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 2.6 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.6 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 0.8 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.4 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.1 0.8 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.3 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 0.2 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.1 0.6 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.2 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 3.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 1.0 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.7 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.8 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.8 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 1.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.5 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 1.7 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.4 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.2 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.0 GO:0004743 pyruvate kinase activity(GO:0004743)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 1.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 2.6 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.7 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.7 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 1.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 2.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.9 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 3.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID ATM PATHWAY ATM pathway
0.0 0.5 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 5.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 2.6 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 1.6 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.1 1.4 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 1.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.7 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 1.1 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.8 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.9 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.6 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.6 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 1.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression