Project

Inflammatory response time course, HUVEC (Wada, 2009)

Navigation
Downloads

Results for GCM1

Z-value: 0.78

Motif logo

Transcription factors associated with GCM1

Gene Symbol Gene ID Gene Info
ENSG00000137270.11 GCM1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GCM1hg38_v1_chr6_-_53148822_531488460.321.2e-01Click!

Activity profile of GCM1 motif

Sorted Z-values of GCM1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GCM1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image
Promoter Score Transcript Gene Gene Info
chr3_+_10164883 3.79 ENST00000256458.5
interleukin 1 receptor associated kinase 2
chr9_-_120929160 3.68 ENST00000540010.1
TNF receptor associated factor 1
chr21_-_44240840 2.28 ENST00000344330.8
ENST00000407780.7
ENST00000400379.7
ENST00000400377.3
inducible T cell costimulator ligand
chr2_+_149330506 1.87 ENST00000334166.9
LY6/PLAUR domain containing 6
chr16_+_3065380 1.72 ENST00000551122.5
ENST00000548807.5
ENST00000528163.6
interleukin 32
chr16_+_67029359 1.60 ENST00000565389.1
core-binding factor subunit beta
chr16_+_3065610 1.58 ENST00000530890.5
ENST00000444393.7
ENST00000533097.6
ENST00000008180.13
ENST00000396890.6
ENST00000525228.5
ENST00000525643.7
ENST00000548652.5
ENST00000525377.6
ENST00000530538.6
ENST00000549213.5
ENST00000552936.5
ENST00000548476.5
ENST00000552664.5
ENST00000552356.5
ENST00000551513.5
ENST00000382213.7
ENST00000548246.1
interleukin 32
chr2_+_111120906 1.52 ENST00000337565.9
ENST00000357757.6
ENST00000308659.12
ENST00000393256.8
ENST00000610735.4
ENST00000615946.4
ENST00000619294.4
ENST00000620862.4
ENST00000621302.4
ENST00000622509.4
ENST00000622612.4
BCL2 like 11
chr8_+_103371490 1.49 ENST00000330295.10
ENST00000415886.2
collagen triple helix repeat containing 1
chr16_+_67029093 1.22 ENST00000561924.6
core-binding factor subunit beta
chr3_+_46407251 1.20 ENST00000399036.4
C-C motif chemokine receptor like 2
chr17_-_7590072 1.20 ENST00000538513.6
ENST00000570788.1
ENST00000250055.3
SRY-box transcription factor 15
chr14_-_91244669 1.04 ENST00000650645.1
G protein-coupled receptor 68
chr2_+_170715317 1.00 ENST00000375281.4
Sp5 transcription factor
chr21_+_32412648 0.98 ENST00000401402.7
ENST00000382699.7
ENST00000300255.7
eva-1 homolog C
chr5_+_141373878 0.95 ENST00000517434.3
ENST00000610583.1
protocadherin gamma subfamily A, 6
chr15_-_78641225 0.94 ENST00000412074.6
cholinergic receptor nicotinic beta 4 subunit
chr15_+_80695277 0.92 ENST00000258884.5
ENST00000558464.1
abhydrolase domain containing 17C, depalmitoylase
chr10_+_79347491 0.92 ENST00000448165.1
peptidylprolyl isomerase F
chr5_+_70025534 0.91 ENST00000515588.1
small EDRK-rich factor 1B
chr16_-_375205 0.88 ENST00000448854.1
post-glycosylphosphatidylinositol attachment to proteins 6
chr14_-_91244508 0.87 ENST00000535815.5
ENST00000529102.1
G protein-coupled receptor 68
chr2_-_106194286 0.80 ENST00000409501.7
ENST00000441952.5
ENST00000457835.5
ENST00000483426.5
ENST00000283148.12
UDP-glucuronate decarboxylase 1
chr8_+_140511286 0.79 ENST00000519533.1
ENST00000220913.10
chromatin accessibility complex subunit 1
chr10_+_49942048 0.78 ENST00000651259.3
ENST00000652716.1
translocase of inner mitochondrial membrane 23 homolog B
chr2_-_24360299 0.77 ENST00000361999.7
intersectin 2
chr2_+_102337148 0.76 ENST00000311734.6
ENST00000409584.5
interleukin 1 receptor like 1
chr1_+_205257180 0.72 ENST00000330675.12
transmembrane and coiled-coil domain family 2
chr16_+_56565070 0.69 ENST00000219162.4
metallothionein 4
chr10_+_79347460 0.69 ENST00000225174.8
peptidylprolyl isomerase F
chr8_+_141128581 0.66 ENST00000519811.6
DENN domain containing 3
chr19_-_18397596 0.66 ENST00000595840.1
ENST00000339007.4
leucine rich repeat containing 25
chr8_+_141128612 0.61 ENST00000518347.5
ENST00000262585.6
ENST00000520986.5
ENST00000523058.5
ENST00000518668.5
DENN domain containing 3
chr22_+_22195753 0.59 ENST00000390285.4
immunoglobulin lambda variable 6-57
chr17_+_82559340 0.58 ENST00000531030.5
ENST00000526383.2
forkhead box K2
chr16_+_67029133 0.57 ENST00000290858.11
ENST00000412916.7
ENST00000564034.6
core-binding factor subunit beta
chr15_-_78641200 0.56 ENST00000261751.8
cholinergic receptor nicotinic beta 4 subunit
chr1_+_23743153 0.56 ENST00000418390.6
elongin A
chr10_-_72215903 0.54 ENST00000526751.5
ENST00000672774.1
ENST00000394919.5
ENST00000394915.7
activating signal cointegrator 1 complex subunit 1
chr12_-_121800558 0.54 ENST00000546227.5
ras homolog family member F, filopodia associated
chr20_-_1325707 0.50 ENST00000381812.5
syndecan binding protein 2
chr1_+_23743462 0.50 ENST00000609199.1
elongin A
chr1_-_13198130 0.49 ENST00000638454.1
PRAME family member 13
chr5_-_143400716 0.49 ENST00000424646.6
ENST00000652686.1
nuclear receptor subfamily 3 group C member 1
chr10_-_72216267 0.49 ENST00000342444.8
ENST00000533958.1
ENST00000672957.1
ENST00000527593.5
ENST00000672940.1
ENST00000530461.5
ENST00000317168.11
ENST00000524829.5
activating signal cointegrator 1 complex subunit 1
chr22_+_43923755 0.48 ENST00000423180.2
ENST00000216180.8
patatin like phospholipase domain containing 3
chr11_-_34511710 0.48 ENST00000620316.4
ENST00000312319.6
E74 like ETS transcription factor 5
chr2_-_131093378 0.46 ENST00000409185.5
ENST00000389915.4
family with sequence similarity 168 member B
chr12_+_11649666 0.46 ENST00000396373.9
ETS variant transcription factor 6
chr20_-_1325746 0.45 ENST00000339987.7
syndecan binding protein 2
chr2_-_287320 0.45 ENST00000401503.5
ALK and LTK ligand 2
chr2_-_160493799 0.45 ENST00000348849.8
RNA binding motif single stranded interacting protein 1
chr2_-_229232039 0.44 ENST00000354069.6
phosphotyrosine interaction domain containing 1
chr6_+_157981826 0.44 ENST00000355585.9
ENST00000640338.1
ENST00000367113.5
synaptojanin 2
chr19_-_47555856 0.44 ENST00000391901.7
ENST00000314121.8
zinc finger protein 541
chr22_-_30326923 0.43 ENST00000215790.12
TBC1 domain family member 10A
chrX_+_35798791 0.43 ENST00000399985.1
MAGE family member B16
chr14_+_75632610 0.43 ENST00000555027.1
FLVCR heme transporter 2
chr3_+_38039199 0.43 ENST00000346219.7
ENST00000308059.11
DLEC1 cilia and flagella associated protein
chr22_-_30326877 0.43 ENST00000403477.7
TBC1 domain family member 10A
chr1_-_11058839 0.42 ENST00000465788.1
spermidine synthase
chr19_+_35031263 0.42 ENST00000640135.1
ENST00000596348.2
sodium voltage-gated channel beta subunit 1
chr3_-_99876104 0.41 ENST00000471562.1
ENST00000495625.2
filamin A interacting protein 1 like
chr20_+_2873420 0.41 ENST00000455631.5
ENST00000399903.7
ENST00000216877.10
ENST00000431048.5
ENST00000430705.5
ENST00000318266.9
protein tyrosine phosphatase receptor type A
chr20_+_380747 0.41 ENST00000217233.9
tribbles pseudokinase 3
chr19_+_11547840 0.41 ENST00000588935.1
calponin 1
chr3_-_10708007 0.40 ENST00000646379.1
ATPase plasma membrane Ca2+ transporting 2
chr11_-_101129042 0.39 ENST00000263463.9
progesterone receptor
chr3_-_47513303 0.37 ENST00000449409.5
ENST00000414236.5
ENST00000444760.5
ENST00000439305.5
elongator acetyltransferase complex subunit 6
chr15_-_77696142 0.37 ENST00000561030.5
leucine rich repeat and Ig domain containing 1
chr22_+_21632751 0.35 ENST00000292779.4
coiled-coil domain containing 116
chr4_-_75724386 0.35 ENST00000677606.1
ENST00000678798.1
ENST00000677970.1
ENST00000677620.1
ENST00000679281.1
ENST00000677333.1
ENST00000676470.1
ENST00000499709.3
ENST00000511868.6
ENST00000678971.1
ENST00000677265.1
ENST00000677952.1
ENST00000678122.1
ENST00000678100.1
ENST00000678062.1
ENST00000676666.1
G3BP stress granule assembly factor 2
chr1_-_145405778 0.34 ENST00000392971.6
NBPF member 20
chr19_+_12791470 0.34 ENST00000302754.6
JunB proto-oncogene, AP-1 transcription factor subunit
chr2_+_90069662 0.34 ENST00000390271.2
immunoglobulin kappa variable 6D-41 (non-functional)
chr1_+_23743366 0.33 ENST00000613537.4
elongin A
chr4_-_75724362 0.33 ENST00000677583.1
G3BP stress granule assembly factor 2
chr4_-_5893075 0.32 ENST00000324989.12
collapsin response mediator protein 1
chr17_-_28897602 0.32 ENST00000394906.6
ENST00000585169.5
flotillin 2
chr2_+_232456146 0.32 ENST00000295463.4
alkaline phosphatase, intestinal
chr18_+_10526011 0.31 ENST00000322897.11
NSF attachment protein gamma
chr16_-_21159441 0.31 ENST00000261383.3
dynein axonemal heavy chain 3
chr10_+_45972482 0.31 ENST00000580018.4
translocase of inner mitochondrial membrane 23
chr9_-_133129395 0.31 ENST00000393157.8
ral guanine nucleotide dissociation stimulator
chr2_+_950836 0.30 ENST00000308624.10
ENST00000407292.1
syntrophin gamma 2
chr16_+_2029636 0.30 ENST00000561844.5
SLC9A3 regulator 2
chrX_-_85379659 0.29 ENST00000262753.9
POF1B actin binding protein
chr3_-_99876193 0.29 ENST00000383694.3
filamin A interacting protein 1 like
chr12_+_65825116 0.29 ENST00000393577.7
high mobility group AT-hook 2
chr11_-_63015831 0.29 ENST00000430500.6
ENST00000336232.7
solute carrier family 22 member 8
chr1_+_11736120 0.29 ENST00000400895.6
ENST00000314340.10
ENST00000376629.8
ENST00000376627.6
ENST00000452018.6
ENST00000510878.1
angiotensin II receptor associated protein
chr7_-_33109363 0.29 ENST00000684207.1
ENST00000297157.8
RP9 pre-mRNA splicing factor
chr17_-_19716604 0.29 ENST00000325411.9
ENST00000350657.9
solute carrier family 47 member 2
chr19_+_11436044 0.28 ENST00000589838.5
protein kinase C substrate 80K-H
chr17_-_3696133 0.28 ENST00000225328.10
purinergic receptor P2X 5
chr17_-_3696033 0.28 ENST00000551178.5
ENST00000552276.5
ENST00000547178.5
purinergic receptor P2X 5
chr4_-_55636284 0.28 ENST00000511469.5
ENST00000264218.7
neuromedin U
chr20_-_49913693 0.28 ENST00000422556.1
spermatogenesis associated 2
chr16_+_72108296 0.28 ENST00000563819.5
ENST00000567142.2
DEAH-box helicase 38
chr19_+_17719471 0.28 ENST00000600186.5
ENST00000597735.5
ENST00000324096.9
microtubule associated protein 1S
chr19_-_17448664 0.27 ENST00000341130.6
transmembrane protein 221
chr9_+_137605674 0.27 ENST00000371421.9
ENST00000431925.6
arrestin domain containing 1
chr17_-_3696198 0.27 ENST00000345901.7
purinergic receptor P2X 5
chr11_+_64291285 0.27 ENST00000422670.7
ENST00000538767.1
potassium two pore domain channel subfamily K member 4
chr17_-_8079903 0.27 ENST00000649809.1
arachidonate 12-lipoxygenase, 12R type
chr19_+_11435619 0.26 ENST00000589126.5
ENST00000588269.1
ENST00000587509.5
ENST00000591462.6
ENST00000592741.5
ENST00000677123.1
ENST00000593101.5
ENST00000587327.5
protein kinase C substrate 80K-H
chr11_+_67416086 0.26 ENST00000445895.2
carnosine synthase 1
chr17_-_19716573 0.26 ENST00000433844.4
solute carrier family 47 member 2
chr20_+_33993646 0.26 ENST00000375114.7
ENST00000448364.5
RALY heterogeneous nuclear ribonucleoprotein
chr16_+_8621717 0.25 ENST00000561758.5
methyltransferase like 22
chr3_-_48595267 0.25 ENST00000328333.12
ENST00000681320.1
collagen type VII alpha 1 chain
chr9_-_35650902 0.25 ENST00000259608.8
ENST00000618781.1
signaling threshold regulating transmembrane adaptor 1
chr22_+_22322452 0.25 ENST00000390290.3
immunoglobulin lambda variable 1-51
chr9_-_135699473 0.25 ENST00000425225.2
ENST00000298466.9
spermatogenesis and oogenesis specific basic helix-loop-helix 1
chr5_-_892533 0.24 ENST00000483173.5
bromodomain containing 9
chr4_+_4387078 0.24 ENST00000504171.1
neuronal vesicle trafficking associated 1
chr16_+_8621679 0.24 ENST00000563958.5
ENST00000381920.8
ENST00000564554.1
methyltransferase like 22
chr3_+_130431463 0.24 ENST00000512836.5
collagen type VI alpha 5 chain
chr1_+_11736068 0.24 ENST00000376637.7
angiotensin II receptor associated protein
chr8_+_144078590 0.24 ENST00000525936.1
exosome component 4
chr20_+_33993904 0.24 ENST00000246194.8
RALY heterogeneous nuclear ribonucleoprotein
chr2_-_89160329 0.24 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr11_+_111255982 0.24 ENST00000637637.1
chromosome 11 open reading frame 53
chr19_+_18340629 0.23 ENST00000597431.2
pyroglutamyl-peptidase I
chr6_-_136526654 0.23 ENST00000611373.1
microtubule associated protein 7
chr1_+_1179676 0.23 ENST00000379288.3
tubulin tyrosine ligase like 10
chr5_-_137735997 0.22 ENST00000505853.1
kelch like family member 3
chr5_-_134367144 0.21 ENST00000265334.9
cyclin dependent kinase like 3
chr1_-_26067622 0.21 ENST00000374272.4
tripartite motif containing 63
chr15_+_45129933 0.21 ENST00000321429.8
ENST00000389037.7
ENST00000558322.5
dual oxidase 1
chr6_-_41154326 0.21 ENST00000426005.6
ENST00000437044.2
ENST00000373127.8
triggering receptor expressed on myeloid cells like 1
chrX_-_64395417 0.20 ENST00000374852.4
myotubularin related protein 8
chr7_-_50093204 0.20 ENST00000419417.5
ENST00000046087.7
zona pellucida binding protein
chr17_+_17179527 0.20 ENST00000579361.1
myosin phosphatase Rho interacting protein
chr16_-_81220370 0.20 ENST00000337114.8
polycystin 1 like 2 (gene/pseudogene)
chr1_+_161215242 0.20 ENST00000367992.7
ENST00000289902.2
Fc fragment of IgE receptor Ig
chr15_+_78340344 0.20 ENST00000299529.7
cellular retinoic acid binding protein 1
chr11_-_8964380 0.19 ENST00000528117.5
ENST00000309134.9
ENST00000534025.6
TMEM9 domain family member B
chr10_+_96000091 0.19 ENST00000424464.5
ENST00000410012.6
ENST00000344386.3
coiled-coil and C2 domain containing 2B
chr7_+_100126954 0.19 ENST00000398075.4
metallo-beta-lactamase domain containing 1
chr7_-_4862015 0.19 ENST00000404991.2
poly(A) polymerase beta
chr2_+_90159840 0.19 ENST00000377032.5
immunoglobulin kappa variable 1D-12
chr22_-_41688799 0.19 ENST00000469028.2
ENST00000463675.6
ENST00000649479.1
ENST00000469522.1
small nuclear ribonucleoprotein 13
chr1_-_235588959 0.18 ENST00000484517.2
G protein subunit gamma 4
chr12_+_55681647 0.18 ENST00000614691.1
methyltransferase like 7B
chr19_-_38315919 0.18 ENST00000591755.5
ENST00000337679.12
ENST00000339413.11
Yip1 interacting factor homolog B, membrane trafficking protein
chr16_-_11392065 0.18 ENST00000599216.5
novel lipoprotein amino terminal region containing protein
chr3_+_40505992 0.17 ENST00000420891.5
ENST00000314529.10
ENST00000418905.1
zinc finger protein 620
chr10_+_102918276 0.17 ENST00000369878.9
ENST00000369875.3
cyclin and CBS domain divalent metal cation transport mediator 2
chr1_+_146949314 0.17 ENST00000617844.4
ENST00000611443.4
NBPF member 12
chrX_-_71068311 0.17 ENST00000374274.8
sorting nexin 12
chr15_-_42094560 0.17 ENST00000290472.4
phospholipase A2 group IVD
chr17_+_42854078 0.17 ENST00000591562.1
ENST00000588033.1
amine oxidase copper containing 3
chr6_-_136526472 0.17 ENST00000454590.5
ENST00000432797.6
microtubule associated protein 7
chr11_-_63015804 0.16 ENST00000535878.5
ENST00000545207.5
solute carrier family 22 member 8
chr7_-_151210488 0.16 ENST00000644661.2
H2B.E variant histone 1
chr19_+_7535697 0.16 ENST00000600737.6
patatin like phospholipase domain containing 6
chr22_+_22811737 0.16 ENST00000390315.3
immunoglobulin lambda variable 3-10
chr2_+_90021567 0.16 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr19_-_37906646 0.16 ENST00000303868.5
WD repeat domain 87
chr7_+_129434424 0.16 ENST00000249344.7
ENST00000435494.2
striatin interacting protein 2
chr11_-_8964927 0.16 ENST00000525069.5
TMEM9 domain family member B
chr18_+_70288991 0.16 ENST00000397942.4
suppressor of cytokine signaling 6
chr7_-_101252133 0.16 ENST00000435848.1
ENST00000474120.5
fission, mitochondrial 1
chr12_+_55681711 0.15 ENST00000394252.4
methyltransferase like 7B
chr16_+_19718264 0.15 ENST00000564186.5
IQ motif containing K
chr3_+_49021605 0.15 ENST00000451378.2
NADH:ubiquinone oxidoreductase complex assembly factor 3
chr1_-_11847772 0.15 ENST00000376480.7
ENST00000610706.1
natriuretic peptide A
chr1_-_11848345 0.14 ENST00000376476.1
natriuretic peptide A
chr19_+_18559000 0.14 ENST00000602094.5
KxDL motif containing 1
chr3_+_52287811 0.13 ENST00000305690.12
ENST00000473032.5
ENST00000436784.7
ENST00000471180.5
glycerate kinase
chr3_-_196515315 0.13 ENST00000397537.3
single-pass membrane protein with coiled-coil domains 1
chr4_+_39406917 0.13 ENST00000257408.5
klotho beta
chr6_-_109440504 0.13 ENST00000520723.5
ENST00000518648.1
ENST00000417394.6
ENST00000521072.7
peptidylprolyl isomerase like 6
chr22_+_22431949 0.13 ENST00000390301.3
immunoglobulin lambda variable 1-36
chr19_-_3547306 0.13 ENST00000589063.5
ENST00000615073.4
major facilitator superfamily domain containing 12
chr17_-_40984297 0.13 ENST00000377755.9
keratin 40
chr16_+_165966 0.12 ENST00000356815.4
hemoglobin subunit mu
chr22_+_22244776 0.12 ENST00000302273.2
ENST00000403807.4
V-set pre-B cell surrogate light chain 1
chr19_-_47048559 0.12 ENST00000253047.7
transmembrane protein 160
chr17_+_15999815 0.12 ENST00000261647.10
tetratricopeptide repeat domain 19
chr11_-_47449129 0.12 ENST00000298854.7
ENST00000524487.5
ENST00000529341.1
ENST00000352508.7
receptor associated protein of the synapse
chr20_+_59123381 0.11 ENST00000637017.1
zinc finger protein 831
chr6_-_30075767 0.11 ENST00000244360.8
ENST00000376751.8
ring finger protein 39
chr20_+_1113257 0.11 ENST00000333082.7
ENST00000381899.8
proteasome inhibitor subunit 1
chr11_-_64744317 0.11 ENST00000419843.1
ENST00000394430.5
RAS guanyl releasing protein 2
chr11_-_41459592 0.11 ENST00000528697.6
ENST00000530763.5
leucine rich repeat containing 4C
chr17_+_45784265 0.11 ENST00000293493.11
ENST00000339069.9
ENST00000619154.4
corticotropin releasing hormone receptor 1
chr6_+_30061231 0.11 ENST00000376782.6
ENST00000359374.8
ENST00000376785.2
ENST00000332435.10
RNA polymerase I subunit H
chr21_-_44914271 0.11 ENST00000522931.5
integrin subunit beta 2
chr19_+_55339867 0.10 ENST00000255613.8
lysine methyltransferase 5C
chr19_-_10119863 0.10 ENST00000589454.5
eukaryotic translation initiation factor 3 subunit G
chr16_-_74421392 0.10 ENST00000339953.9
ENST00000620745.1
ENST00000682950.1
C-type lectin domain family 18 member B
chr11_-_8168987 0.10 ENST00000425599.6
ENST00000531450.1
ENST00000309737.11
ENST00000419822.2
ENST00000335425.7
ENST00000343202.8
RIC3 acetylcholine receptor chaperone
chr19_+_7522605 0.10 ENST00000264079.11
mucolipin TRP cation channel 1
chr1_-_68449927 0.10 ENST00000262340.6
retinoid isomerohydrolase RPE65
chr10_+_119029711 0.10 ENST00000425699.3
nanos C2HC-type zinc finger 1
chr16_+_1972035 0.10 ENST00000568546.6
ENST00000615855.4
transducin beta like 3
chr11_-_35418966 0.09 ENST00000531628.2
solute carrier family 1 member 2
chr22_-_32202451 0.09 ENST00000248983.8
ret finger protein like 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.5 1.5 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.4 1.2 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.2 1.5 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.2 1.5 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.2 1.9 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 3.8 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.1 0.4 GO:0070378 positive regulation of ERK5 cascade(GO:0070378)
0.1 0.4 GO:1901859 negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859) negative regulation of ATP biosynthetic process(GO:2001170)
0.1 0.8 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.3 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.1 0.3 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.1 0.3 GO:0035498 carnosine metabolic process(GO:0035498)
0.1 3.4 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.1 0.4 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 0.5 GO:0046618 drug export(GO:0046618)
0.1 0.5 GO:0007296 vitellogenesis(GO:0007296)
0.1 1.0 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 0.3 GO:2000685 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.1 2.3 GO:0006972 hyperosmotic response(GO:0006972)
0.1 0.4 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.1 0.5 GO:0001712 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.1 0.2 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.1 0.2 GO:0002445 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) positive regulation of type I hypersensitivity(GO:0001812) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892) mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.1 0.2 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.1 0.3 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.1 0.5 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.4 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.1 0.2 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.1 1.1 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 0.3 GO:0044860 protein localization to plasma membrane raft(GO:0044860)
0.1 0.2 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.1 0.2 GO:0042335 cuticle development(GO:0042335)
0.1 0.2 GO:1904397 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.0 0.3 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.0 0.2 GO:0018094 protein polyglycylation(GO:0018094)
0.0 1.0 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.2 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.7 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.5 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 3.6 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 1.9 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.2 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.3 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.5 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.3 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.2 GO:2000852 regulation of corticosterone secretion(GO:2000852)
0.0 0.4 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.8 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
0.0 0.8 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.2 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.4 GO:2000188 regulation of cholesterol homeostasis(GO:2000188)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.4 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.8 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.1 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.6 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.3 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 1.3 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.2 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.1 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.1 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0045259 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.3 0.8 GO:0008623 CHRAC(GO:0008623)
0.1 1.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 1.4 GO:0070449 elongin complex(GO:0070449)
0.1 0.3 GO:0036156 inner dynein arm(GO:0036156)
0.1 1.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 1.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0035976 AP1 complex(GO:0035976)
0.0 0.3 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.8 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.2 GO:0098845 postsynaptic endosome(GO:0098845)
0.0 0.3 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.3 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:0001651 dense fibrillar component(GO:0001651)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 1.7 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:1990879 CST complex(GO:1990879)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 1.3 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 2.2 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.3 0.8 GO:0002113 interleukin-33 binding(GO:0002113)
0.2 3.7 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.4 GO:0004766 spermidine synthase activity(GO:0004766)
0.1 1.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 0.3 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.5 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 0.5 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.1 0.4 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.1 0.3 GO:0097604 temperature-gated cation channel activity(GO:0097604)
0.1 1.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.4 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.8 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.5 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 0.3 GO:0035501 MH1 domain binding(GO:0035501)
0.1 0.5 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.3 GO:0052596 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 0.3 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.1 1.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.0 0.2 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.3 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.4 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 1.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 1.5 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:0034512 box C/D snoRNA binding(GO:0034512)
0.0 0.6 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.8 GO:0070403 NAD+ binding(GO:0070403)
0.0 1.3 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.2 GO:0019863 immunoglobulin receptor activity(GO:0019763) IgE binding(GO:0019863)
0.0 0.4 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 1.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.4 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.0 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.0 0.3 GO:0031005 filamin binding(GO:0031005)
0.0 3.3 GO:0005125 cytokine activity(GO:0005125)
0.0 0.1 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 3.7 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 1.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 3.7 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.8 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 1.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 2.3 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels