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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for GCM2

Z-value: 0.75

Motif logo

Transcription factors associated with GCM2

Gene Symbol Gene ID Gene Info
ENSG00000124827.7 GCM2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GCM2hg38_v1_chr6_-_10882037_108820480.009.8e-01Click!

Activity profile of GCM2 motif

Sorted Z-values of GCM2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GCM2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr8_-_92103217 1.70 ENST00000615601.4
ENST00000523629.5
RUNX1 partner transcriptional co-repressor 1
chr11_+_7576408 1.48 ENST00000533792.5
PPFIA binding protein 2
chr1_+_14924100 1.14 ENST00000361144.9
kazrin, periplakin interacting protein
chr11_+_7513966 1.14 ENST00000299492.9
PPFIA binding protein 2
chr15_-_92655712 1.10 ENST00000327355.6
family with sequence similarity 174 member B
chr1_+_99646025 0.98 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
palmdelphin
chr1_+_26111139 0.94 ENST00000619836.4
ENST00000444713.5
PDLIM1 interacting kinase 1 like
chr5_+_123512214 0.79 ENST00000511130.6
ENST00000512718.7
casein kinase 1 gamma 3
chr1_-_39901996 0.78 ENST00000397332.2
MYCL proto-oncogene, bHLH transcription factor
chr6_-_31897200 0.73 ENST00000395728.7
ENST00000375528.8
euchromatic histone lysine methyltransferase 2
chr12_-_49828394 0.72 ENST00000335999.7
NCK associated protein 5 like
chr14_-_105168753 0.70 ENST00000331782.8
ENST00000347004.2
jagged canonical Notch ligand 2
chr14_+_64504574 0.67 ENST00000358738.3
zinc finger and BTB domain containing 1
chr17_-_27793716 0.67 ENST00000646938.1
nitric oxide synthase 2
chr5_+_177133005 0.64 ENST00000510954.5
ENST00000354179.8
nuclear receptor binding SET domain protein 1
chr13_+_31846713 0.63 ENST00000645780.1
FRY microtubule binding protein
chr6_+_7107941 0.62 ENST00000379938.7
ENST00000467782.5
ENST00000334984.10
ENST00000349384.10
ras responsive element binding protein 1
chr17_+_6070361 0.59 ENST00000317744.10
WSC domain containing 1
chr9_-_127755243 0.57 ENST00000629203.2
ENST00000420366.5
SH2 domain containing 3C
chr1_-_39901861 0.56 ENST00000372816.3
ENST00000372815.1
MYCL proto-oncogene, bHLH transcription factor
chr7_-_101165114 0.54 ENST00000445482.2
VGF nerve growth factor inducible
chr7_+_12687625 0.54 ENST00000651779.1
ENST00000404894.1
ADP ribosylation factor like GTPase 4A
chr19_-_38869921 0.53 ENST00000593809.1
ENST00000593424.5
Ras and Rab interactor like
chr12_+_57522801 0.53 ENST00000355673.8
ENST00000546632.1
ENST00000549623.1
methyl-CpG binding domain protein 6
chr19_+_35000275 0.50 ENST00000317991.10
ENST00000680623.1
GRAM domain containing 1A
chr13_-_98577131 0.49 ENST00000397517.6
serine/threonine kinase 24
chr10_+_92689946 0.49 ENST00000282728.10
hematopoietically expressed homeobox
chr17_-_67245165 0.48 ENST00000580168.5
ENST00000358691.10
helicase with zinc finger
chr12_+_55997180 0.47 ENST00000356124.8
ENST00000266971.8
ENST00000394115.6
ENST00000547586.5
ENST00000552258.5
ENST00000548274.5
ENST00000546833.5
sulfite oxidase
chr9_+_127612222 0.46 ENST00000637953.1
ENST00000636962.2
syntaxin binding protein 1
chr2_-_219543793 0.43 ENST00000243776.11
chondroitin polymerizing factor
chr12_+_14973020 0.43 ENST00000266395.3
phosphodiesterase 6H
chr9_+_70043840 0.43 ENST00000377182.5
MAM domain containing 2
chr6_-_6007511 0.43 ENST00000616243.1
neuritin 1
chr9_+_127612257 0.42 ENST00000637173.2
ENST00000630492.2
ENST00000627871.2
ENST00000373302.8
ENST00000373299.5
ENST00000650920.1
ENST00000476182.3
syntaxin binding protein 1
chr11_+_117232625 0.42 ENST00000534428.5
ENST00000300650.9
ring finger protein 214
chrX_-_63785510 0.42 ENST00000437457.6
ENST00000374878.5
ENST00000623517.3
Cdc42 guanine nucleotide exchange factor 9
chr19_+_17470474 0.42 ENST00000598424.5
ENST00000252595.12
solute carrier family 27 member 1
chr5_-_173328407 0.41 ENST00000265087.9
stanniocalcin 2
chr18_-_31684504 0.41 ENST00000383131.3
ENST00000237019.11
ENST00000306851.10
beta-1,4-galactosyltransferase 6
chr2_+_188292771 0.40 ENST00000359135.7
GULP PTB domain containing engulfment adaptor 1
chr9_-_124500986 0.40 ENST00000373587.3
nuclear receptor subfamily 5 group A member 1
chr7_+_121328991 0.40 ENST00000222462.3
Wnt family member 16
chr14_-_75069478 0.39 ENST00000555463.1
acylphosphatase 1
chr9_+_4490388 0.39 ENST00000262352.8
solute carrier family 1 member 1
chr14_-_49586325 0.39 ENST00000557519.1
ENST00000396020.7
ENST00000554075.2
ENST00000245458.11
ribosomal protein S29
chr5_-_177311882 0.39 ENST00000513169.1
ENST00000423571.6
ENST00000502529.1
ENST00000427908.6
MAX dimerization protein 3
chr1_+_2050387 0.39 ENST00000378567.8
protein kinase C zeta
chr7_-_101165558 0.39 ENST00000611537.1
ENST00000249330.3
VGF nerve growth factor inducible
chr6_+_130018565 0.39 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL histone methyl-lysine binding protein 3
chr17_-_4903088 0.38 ENST00000649488.2
cholinergic receptor nicotinic epsilon subunit
chr11_+_66857056 0.38 ENST00000309602.5
ENST00000393952.3
leucine rich repeat and fibronectin type III domain containing 4
chr7_+_5879827 0.38 ENST00000416608.5
oncomodulin
chr1_+_156728442 0.37 ENST00000368218.8
ENST00000368216.9
ribosomal RNA adenine dimethylase domain containing 1
chrX_-_63785149 0.37 ENST00000671741.2
ENST00000625116.3
ENST00000624355.1
Cdc42 guanine nucleotide exchange factor 9
chrX_+_47078380 0.37 ENST00000352078.8
regucalcin
chrX_+_47078434 0.37 ENST00000397180.6
regucalcin
chr11_-_58578096 0.37 ENST00000528954.5
ENST00000528489.1
leupaxin
chr17_+_1742836 0.36 ENST00000324015.7
ENST00000450523.6
ENST00000453723.5
ENST00000453066.6
ENST00000382061.5
serpin family F member 2
chr19_-_19515542 0.36 ENST00000585580.4
testis specific serine kinase 6
chr12_-_43552196 0.35 ENST00000389420.8
ADAM metallopeptidase with thrombospondin type 1 motif 20
chr12_+_56224318 0.35 ENST00000267023.9
ENST00000380198.6
ENST00000341463.5
nucleic acid binding protein 2
chr10_+_74824919 0.34 ENST00000648828.1
ENST00000648725.1
lysine acetyltransferase 6B
chr5_-_524322 0.34 ENST00000644203.1
ENST00000514375.1
ENST00000264938.8
solute carrier family 9 member A3
chrX_+_47078330 0.34 ENST00000457380.5
regucalcin
chr1_+_14945775 0.33 ENST00000400797.3
kazrin, periplakin interacting protein
chr22_+_19718390 0.33 ENST00000383045.7
ENST00000438754.6
septin 5
chr3_+_186666003 0.33 ENST00000232003.5
histidine rich glycoprotein
chr6_+_7107597 0.32 ENST00000379933.7
ENST00000491191.5
ENST00000471433.5
ras responsive element binding protein 1
chr3_-_86991135 0.32 ENST00000398399.7
vestigial like family member 3
chr14_-_64504570 0.32 ENST00000394715.1
zinc finger and BTB domain containing 25
chr4_-_146521891 0.32 ENST00000394059.8
ENST00000502607.1
ENST00000335472.12
ENST00000432059.6
solute carrier family 10 member 7
chr20_-_1002264 0.32 ENST00000400634.2
ENST00000217260.9
R-spondin 4
chr11_+_63938971 0.32 ENST00000539656.5
ENST00000377793.9
N-alpha-acetyltransferase 40, NatD catalytic subunit
chr9_+_134025455 0.31 ENST00000603928.3
ENST00000432807.1
BRD3 opposite strand
chr17_+_6071075 0.31 ENST00000574232.5
ENST00000539421.1
WSC domain containing 1
chr9_+_136712531 0.31 ENST00000371692.9
divergent protein kinase domain 1B
chr15_-_74956758 0.31 ENST00000322177.6
ribonuclease P and MRP subunit p25
chr12_-_48004467 0.30 ENST00000380518.8
collagen type II alpha 1 chain
chr7_-_44325421 0.30 ENST00000395747.6
ENST00000347193.8
ENST00000346990.8
ENST00000258682.10
ENST00000353625.8
ENST00000421607.1
ENST00000424197.5
calcium/calmodulin dependent protein kinase II beta
chr5_-_91383310 0.30 ENST00000265138.4
arrestin domain containing 3
chr19_+_17871937 0.30 ENST00000222248.4
solute carrier family 5 member 5
chr13_-_98577094 0.29 ENST00000539966.6
serine/threonine kinase 24
chr2_+_188292814 0.28 ENST00000409580.5
ENST00000409637.7
GULP PTB domain containing engulfment adaptor 1
chr9_+_125748175 0.27 ENST00000491787.7
ENST00000447726.6
PBX homeobox 3
chr7_-_44325653 0.27 ENST00000440254.6
calcium/calmodulin dependent protein kinase II beta
chr3_+_155080088 0.27 ENST00000462745.5
membrane metalloendopeptidase
chr3_+_23945271 0.26 ENST00000312521.9
nuclear receptor subfamily 1 group D member 2
chr7_-_5423543 0.26 ENST00000399537.8
trinucleotide repeat containing 18
chr2_+_232406836 0.26 ENST00000295453.8
alkaline phosphatase, germ cell
chr7_-_8262052 0.26 ENST00000396675.7
ENST00000430867.5
ENST00000402384.8
ENST00000265577.11
islet cell autoantigen 1
chr17_-_7219813 0.25 ENST00000399510.8
ENST00000648172.8
discs large MAGUK scaffold protein 4
chr7_-_5423826 0.25 ENST00000430969.6
trinucleotide repeat containing 18
chr13_-_20161038 0.25 ENST00000241125.4
gap junction protein alpha 3
chr7_-_27130182 0.25 ENST00000511914.1
homeobox A4
chr1_-_156500763 0.24 ENST00000348159.9
ENST00000489057.1
myocyte enhancer factor 2D
chrX_-_154805386 0.24 ENST00000393531.5
ENST00000369534.8
ENST00000453245.5
ENST00000428488.1
ENST00000369531.1
membrane palmitoylated protein 1
chr19_-_51368979 0.24 ENST00000601435.1
ENST00000291715.5
claudin domain containing 2
chr2_-_197310646 0.24 ENST00000647377.1
ankyrin repeat domain 44
chr3_-_19946970 0.23 ENST00000344838.8
EF-hand domain family member B
chr15_+_40569290 0.23 ENST00000315616.12
ENST00000559271.1
ENST00000616318.1
RNA pseudouridine synthase domain containing 2
chr12_-_51270351 0.23 ENST00000603798.6
small cell adhesion glycoprotein
chr19_+_40717091 0.23 ENST00000263370.3
inositol-trisphosphate 3-kinase C
chr2_-_44361555 0.22 ENST00000409957.5
prolyl endopeptidase like
chr7_-_44325490 0.22 ENST00000350811.7
calcium/calmodulin dependent protein kinase II beta
chr4_-_17781613 0.22 ENST00000265018.4
family with sequence similarity 184 member B
chr11_+_66638661 0.21 ENST00000396053.9
ENST00000408993.6
RNA binding motif protein 4
chr22_+_31093358 0.21 ENST00000404574.5
smoothelin
chr14_-_21098848 0.21 ENST00000556174.5
ENST00000554478.5
ENST00000553980.1
ENST00000421093.6
zinc finger protein 219
chr3_-_122022122 0.21 ENST00000393631.5
ENST00000273691.7
ENST00000344209.10
immunoglobulin like domain containing receptor 1
chr18_-_14132423 0.20 ENST00000589498.5
ENST00000590202.3
zinc finger protein 519
chr19_+_45039040 0.20 ENST00000221455.8
ENST00000391953.8
ENST00000588936.5
CLK4 associating serine/arginine rich protein
chrX_+_43654888 0.20 ENST00000542639.5
monoamine oxidase A
chrX_-_154805516 0.20 ENST00000413259.7
membrane palmitoylated protein 1
chr3_-_50567711 0.20 ENST00000357203.8
chromosome 3 open reading frame 18
chr14_-_77616630 0.20 ENST00000216484.7
serine palmitoyltransferase long chain base subunit 2
chr16_+_28985043 0.19 ENST00000395456.7
ENST00000564277.5
ENST00000630764.2
ENST00000354453.7
linker for activation of T cells
chrX_-_136880715 0.19 ENST00000431446.7
ENST00000320676.11
ENST00000562646.5
RNA binding motif protein X-linked
chr11_-_74170975 0.19 ENST00000539061.6
ENST00000680645.1
ENST00000334126.12
ENST00000680718.1
C2 domain containing 3 centriole elongation regulator
chr5_-_73448769 0.19 ENST00000615637.3
forkhead box D1
chr14_-_21098570 0.19 ENST00000360947.8
zinc finger protein 219
chr1_+_960549 0.19 ENST00000338591.8
ENST00000622660.1
kelch like family member 17
chr11_-_796185 0.19 ENST00000533385.5
ENST00000528936.5
ENST00000629634.2
ENST00000625752.2
ENST00000528606.5
ENST00000320230.9
solute carrier family 25 member 22
chr19_+_45039509 0.19 ENST00000544944.6
CLK4 associating serine/arginine rich protein
chr11_+_63681444 0.18 ENST00000341307.6
ENST00000356000.7
ENST00000542238.5
reticulon 3
chr6_-_32109291 0.18 ENST00000479795.1
ENST00000647633.1
ENST00000644971.2
ENST00000375244.7
tenascin XB
chr14_+_92513766 0.18 ENST00000216487.12
ENST00000620541.4
ENST00000557762.1
Ras and Rab interactor 3
chr11_-_74170792 0.18 ENST00000680231.1
ENST00000681143.1
ENST00000679906.1
ENST00000681310.1
ENST00000414160.7
ENST00000538361.2
C2 domain containing 3 centriole elongation regulator
chr9_-_69014090 0.18 ENST00000377276.5
protein kinase cAMP-activated catalytic subunit gamma
chr11_+_63681483 0.18 ENST00000339997.8
ENST00000540798.5
ENST00000545432.5
ENST00000543552.5
ENST00000377819.10
ENST00000537981.5
reticulon 3
chr19_-_38388020 0.17 ENST00000334928.11
ENST00000587676.1
gametogenetin
chr3_+_155079847 0.17 ENST00000615825.2
membrane metalloendopeptidase
chr1_+_150549734 0.17 ENST00000674043.1
ENST00000674058.1
ADAMTS like 4
chr1_-_16431371 0.17 ENST00000612240.1
spermatogenesis associated 21
chr20_+_43514426 0.17 ENST00000422861.3
L3MBTL histone methyl-lysine binding protein 1
chr22_-_29315656 0.17 ENST00000401450.3
ENST00000216101.7
RAS like family 10 member A
chr3_+_155079663 0.17 ENST00000460393.6
membrane metalloendopeptidase
chr3_-_50567646 0.16 ENST00000426034.5
ENST00000441239.5
chromosome 3 open reading frame 18
chr15_-_93089192 0.16 ENST00000329082.11
repulsive guidance molecule BMP co-receptor a
chr3_+_155079911 0.16 ENST00000675418.2
membrane metalloendopeptidase
chr19_-_10565990 0.16 ENST00000539027.5
ENST00000312962.12
ENST00000543682.3
ENST00000652042.1
ENST00000432197.5
KRI1 homolog
chr16_+_28985251 0.16 ENST00000360872.9
ENST00000566177.5
linker for activation of T cells
chr17_-_3893040 0.15 ENST00000158166.5
ENST00000348335.7
calcium/calmodulin dependent protein kinase kinase 1
chr1_+_150549384 0.15 ENST00000369041.9
ENST00000271643.9
ADAMTS like 4
chr19_-_51027662 0.15 ENST00000594768.5
kallikrein related peptidase 11
chr2_+_178194460 0.15 ENST00000392505.6
ENST00000359685.7
ENST00000357080.8
ENST00000190611.9
ENST00000409045.7
oxysterol binding protein like 6
chr19_-_14206168 0.15 ENST00000361434.7
ENST00000340736.10
adhesion G protein-coupled receptor L1
chr14_+_75069577 0.15 ENST00000238686.8
zinc finger C2HC-type containing 1C
chr14_+_75069632 0.15 ENST00000439583.2
ENST00000554763.2
ENST00000524913.3
ENST00000525046.2
ENST00000674086.1
ENST00000526130.2
ENST00000674094.1
ENST00000532198.2
zinc finger C2HC-type containing 1C
chr16_+_71358713 0.15 ENST00000349553.9
ENST00000302628.9
ENST00000562305.5
calbindin 2
chr22_+_19723525 0.15 ENST00000366425.4
glycoprotein Ib platelet subunit beta
chr11_-_6320494 0.15 ENST00000303927.4
ENST00000530979.1
caveolae associated protein 3
chr3_+_15206179 0.15 ENST00000253693.7
calpain 7
chr11_-_120120880 0.15 ENST00000526881.1
tripartite motif containing 29
chr2_-_219571241 0.14 ENST00000373876.5
ENST00000603926.5
ENST00000373873.8
ENST00000289656.3
obscurin like cytoskeletal adaptor 1
chr13_-_36131286 0.14 ENST00000255448.8
ENST00000379892.4
doublecortin like kinase 1
chr1_-_202807988 0.14 ENST00000648738.1
ENST00000648354.1
lysine demethylase 5B
chr17_-_8118489 0.14 ENST00000380149.6
ENST00000448843.7
arachidonate lipoxygenase 3
chr12_-_52618559 0.14 ENST00000305748.7
keratin 73
chr17_-_46193372 0.14 ENST00000638275.1
KAT8 regulatory NSL complex subunit 1
chr19_+_22286433 0.14 ENST00000601693.2
zinc finger protein 729
chr17_-_46193412 0.14 ENST00000432791.7
KAT8 regulatory NSL complex subunit 1
chr2_-_44361485 0.14 ENST00000438314.1
ENST00000409411.6
ENST00000409936.5
prolyl endopeptidase like
chr2_-_40512361 0.14 ENST00000403092.5
solute carrier family 8 member A1
chr5_+_100535317 0.14 ENST00000312637.5
family with sequence similarity 174 member A
chr11_+_63681573 0.14 ENST00000354497.4
reticulon 3
chr12_-_51270274 0.14 ENST00000605627.1
small cell adhesion glycoprotein
chr18_+_3449413 0.13 ENST00000549253.5
TGFB induced factor homeobox 1
chr11_+_5488685 0.13 ENST00000322641.5
olfactory receptor family 52 subfamily D member 1
chr7_-_8262668 0.13 ENST00000446305.1
islet cell autoantigen 1
chr2_+_219544002 0.13 ENST00000421791.1
ENST00000373883.4
ENST00000451952.1
transmembrane protein 198
chr17_-_10114546 0.13 ENST00000323816.8
growth arrest specific 7
chr9_-_21974821 0.13 ENST00000304494.10
ENST00000579122.1
ENST00000498124.1
cyclin dependent kinase inhibitor 2A
chr17_-_46192767 0.13 ENST00000262419.10
KAT8 regulatory NSL complex subunit 1
chr16_+_28984795 0.13 ENST00000395461.7
linker for activation of T cells
chr1_+_75724431 0.12 ENST00000541113.6
ENST00000680805.1
acyl-CoA dehydrogenase medium chain
chr11_+_31816266 0.12 ENST00000644607.1
ENST00000646221.1
ENST00000643671.1
ENST00000643931.1
ENST00000642614.1
ENST00000642818.1
ENST00000645848.1
ENST00000506388.2
ENST00000645824.1
ENST00000532942.5
PAX6 upstream antisense RNA
novel protein
chr5_+_177086867 0.12 ENST00000503708.5
ENST00000393648.6
ENST00000514472.1
ENST00000502906.5
ENST00000292408.9
ENST00000510911.5
fibroblast growth factor receptor 4
chr5_+_123512087 0.12 ENST00000345990.8
casein kinase 1 gamma 3
chr14_-_67515153 0.12 ENST00000555994.6
transmembrane protein 229B
chr11_-_5324297 0.11 ENST00000624187.1
olfactory receptor family 51 subfamily B member 2
chr19_-_17460893 0.11 ENST00000301944.3
nucleoredoxin like 1
chr5_+_134905100 0.11 ENST00000512783.5
ENST00000254908.11
pterin-4 alpha-carbinolamine dehydratase 2
chr12_-_16606102 0.11 ENST00000537304.6
LIM domain only 3
chr11_-_118152775 0.11 ENST00000324727.9
sodium voltage-gated channel beta subunit 4
chr17_-_5123102 0.11 ENST00000250076.7
zinc finger protein 232
chrX_-_41923547 0.11 ENST00000378163.7
calcium/calmodulin dependent serine protein kinase
chr12_-_16605939 0.11 ENST00000541295.5
ENST00000535535.5
LIM domain only 3
chr19_+_35292145 0.11 ENST00000595791.5
ENST00000597035.5
ENST00000537831.2
ENST00000392213.8
myelin associated glycoprotein
chr16_+_24845987 0.11 ENST00000565769.5
ENST00000569520.5
solute carrier family 5 member 11
chr19_+_7348930 0.10 ENST00000668164.2
Rho/Rac guanine nucleotide exchange factor 18
chr12_+_4909895 0.10 ENST00000638821.1
ENST00000382545.5
novel transcript, sense overlapping KCNA1
potassium voltage-gated channel subfamily A member 1
chr16_-_10182394 0.10 ENST00000330684.4
glutamate ionotropic receptor NMDA type subunit 2A
chr22_-_29555178 0.10 ENST00000418021.1
THO complex 5
chr19_+_35292125 0.10 ENST00000600291.5
ENST00000361922.8
myelin associated glycoprotein
chr15_+_78872954 0.10 ENST00000558746.5
ENST00000558830.5
ENST00000559345.5
mortality factor 4 like 1
chr17_+_29593118 0.10 ENST00000394859.8
ankyrin repeat domain 13B
chr10_+_44959780 0.10 ENST00000340258.10
ENST00000427758.5
Ras association domain family member 4
chr14_-_77271200 0.10 ENST00000298352.5
neuroglobin
chr2_-_40512423 0.10 ENST00000402441.5
ENST00000448531.1
solute carrier family 8 member A1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.3 1.1 GO:1903627 regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634)
0.2 0.9 GO:1903294 regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296)
0.2 0.5 GO:2000176 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.2 1.3 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.2 0.5 GO:0061011 hepatic duct development(GO:0061011)
0.2 0.6 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.4 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.1 0.5 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.1 0.3 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 0.4 GO:0007538 primary sex determination(GO:0007538)
0.1 0.4 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.1 0.7 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.1 0.8 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.3 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.4 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 0.6 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.1 0.4 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.3 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1 0.3 GO:0021997 neural plate axis specification(GO:0021997)
0.1 0.2 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.0 0.1 GO:0043465 fermentation(GO:0006113) regulation of fermentation(GO:0043465)
0.0 0.4 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.7 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.5 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:0051793 medium-chain fatty acid catabolic process(GO:0051793)
0.0 0.4 GO:0000101 sulfur amino acid transport(GO:0000101)
0.0 0.2 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.0 0.8 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.1 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 0.2 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.0 0.2 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.7 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.4 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.4 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.1 GO:0008614 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.6 GO:0097369 sodium ion import(GO:0097369)
0.0 1.7 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.9 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.9 GO:0048679 regulation of axon regeneration(GO:0048679)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.4 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.0 0.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.3 GO:0035878 nail development(GO:0035878)
0.0 0.2 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.1 GO:0033058 directional locomotion(GO:0033058)
0.0 0.2 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 0.3 GO:0007512 adult heart development(GO:0007512)
0.0 0.3 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.2 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.4 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.3 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.3 GO:0060174 limb bud formation(GO:0060174)
0.0 0.4 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.1 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.3 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0046222 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.0 0.2 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.1 GO:0042851 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.0 0.7 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.4 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.2 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.4 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 1.6 GO:0070268 cornification(GO:0070268)
0.0 0.5 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.5 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.4 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.1 GO:0038110 interleukin-4-mediated signaling pathway(GO:0035771) interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.1 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.1 0.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 1.5 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0045179 apical cortex(GO:0045179)
0.0 0.5 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:1990393 3M complex(GO:1990393)
0.0 0.5 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.7 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.5 GO:0042629 mast cell granule(GO:0042629)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0004341 gluconolactonase activity(GO:0004341)
0.1 0.7 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.4 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.5 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.1 0.3 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1 0.4 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.3 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.1 0.7 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.2 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.4 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.6 GO:0046975 histone methyltransferase activity (H4-K20 specific)(GO:0042799) histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.2 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.1 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.2 GO:0031208 POZ domain binding(GO:0031208)
0.0 1.3 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.4 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.4 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.1 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.0 0.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.1 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.7 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.1 GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.0 0.4 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.3 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 1.0 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.4 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.2 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.7 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.0 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.7 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 0.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.8 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.7 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.7 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules