ISMARA results: GMEB1

Project

Inflammatory response time course, HUVEC (Wada, 2009)

Navigation

Downloads

Results for GMEB1

Z-value: 1.18

Motif logo

Transcription factors associated with GMEB1

Gene Symbol	Gene ID	Gene Info
GMEB1 Ensembl NCBI GeneCards UniProt	ENSG00000162419.13	GMEB1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
GMEB1	hg38_v1_chr1_+_28668746_28668815	0.39	5.2e-02	Click!

Activity profile of GMEB1 motif

Sorted Z-values of GMEB1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GMEB1

View svg image
View png image

Top targets:

Search:

Show entries

Promoter	Score	Transcript	Gene	Gene Info
chr1_+_65147514 Show fit	4.18	ENST00000545314.5	AK4 Ensembl NCBI GeneCards UniProt Show fit	adenylate kinase 4
chr16_-_75556214 Show fit	3.39	ENST00000568377.5 ENST00000565067.5 ENST00000258173.11	TMEM231 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 231
chr9_-_120929160 Show fit	2.67	ENST00000540010.1	TRAF1 Ensembl NCBI GeneCards UniProt Show fit	TNF receptor associated factor 1
chr15_+_88635626 Show fit	2.63	ENST00000379224.10	ISG20 Ensembl NCBI GeneCards UniProt Show fit	interferon stimulated exonuclease gene 20
chr4_+_88378842 Show fit	2.50	ENST00000264346.12	HERC6 Ensembl NCBI GeneCards UniProt Show fit	HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr10_-_48604952 Show fit	2.50	ENST00000417912.6	ARHGAP22 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 22
chr1_-_209651291 Show fit	2.35	ENST00000391911.5 ENST00000415782.1	LAMB3 Ensembl NCBI GeneCards UniProt Show fit	laminin subunit beta 3
chr1_+_65147657 Show fit	2.18	ENST00000546702.5	AK4 Ensembl NCBI GeneCards UniProt Show fit	adenylate kinase 4
chr7_-_24980148 Show fit	2.16	ENST00000313367.7	OSBPL3 Ensembl NCBI GeneCards UniProt Show fit	oxysterol binding protein like 3
chr4_+_88378733 Show fit	2.10	ENST00000273960.7 ENST00000380265.9	HERC6 Ensembl NCBI GeneCards UniProt Show fit	HECT and RLD domain containing E3 ubiquitin protein ligase family member 6

Showing 1 to 10 of 200 entries

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	8.4	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
1.7	5.2	GO:0046967	cytosol to ER transport(GO:0046967)
0.0	4.6	GO:0002244	hematopoietic progenitor cell differentiation(GO:0002244)
0.1	3.3	GO:0003351	epithelial cilium movement(GO:0003351) sperm capacitation(GO:0048240)
0.3	2.9	GO:0038110	interleukin-2-mediated signaling pathway(GO:0038110)
0.1	2.8	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.7	2.6	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
0.6	2.6	GO:0046900	tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.4	2.6	GO:0035617	stress granule disassembly(GO:0035617)
0.2	2.5	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)

Showing 1 to 10 of 410 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	5.2	GO:0042825	TAP complex(GO:0042825)
0.2	3.6	GO:0036038	MKS complex(GO:0036038)
0.8	3.3	GO:0097229	sperm end piece(GO:0097229)
0.0	3.1	GO:0030018	Z disc(GO:0030018)
0.0	2.9	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	2.7	GO:0005923	bicellular tight junction(GO:0005923)
0.3	2.3	GO:0005610	laminin-5 complex(GO:0005610)
0.0	2.3	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	2.3	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.2	2.2	GO:0042612	MHC class I protein complex(GO:0042612)

Showing 1 to 10 of 171 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	7.9	GO:0046899	nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.8	7.4	GO:0046978	TAP binding(GO:0046977) TAP1 binding(GO:0046978)
0.0	7.4	GO:0005096	GTPase activator activity(GO:0005096)
0.0	5.3	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.0	3.8	GO:0017124	SH3 domain binding(GO:0017124)
0.0	3.8	GO:0019787	ubiquitin-like protein transferase activity(GO:0019787)
0.0	3.7	GO:0003714	transcription corepressor activity(GO:0003714)
0.0	3.1	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.2	2.7	GO:0031996	thioesterase binding(GO:0031996)
0.9	2.6	GO:0008859	exoribonuclease II activity(GO:0008859)

Showing 1 to 10 of 283 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	5.4	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.1	4.8	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	4.0	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	3.8	PID PLK1 PATHWAY	PLK1 signaling events
0.2	2.9	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.1	2.8	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	2.4	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	2.4	PID P73PATHWAY	p73 transcription factor network
0.0	2.2	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	2.0	ST G ALPHA I PATHWAY	G alpha i Pathway

Showing 1 to 10 of 43 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	6.6	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	4.7	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	4.0	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.1	3.6	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	3.5	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.1	3.2	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2	2.9	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	2.9	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	2.9	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	2.6	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall

Showing 1 to 10 of 82 entries

Results for GMEB1

Z-value: 1.18

Motif logo

Transcription factors associated with GMEB1

Activity-expression correlation:

Activity profile of GMEB1 motif

Sorted Z-values of GMEB1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GMEB1

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: