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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for HAND1

Z-value: 0.60

Motif logo

Transcription factors associated with HAND1

Gene Symbol Gene ID Gene Info
ENSG00000113196.3 HAND1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HAND1hg38_v1_chr5_-_154478218_154478234-0.321.2e-01Click!

Activity profile of HAND1 motif

Sorted Z-values of HAND1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HAND1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_+_227813834 2.66 ENST00000358813.5
ENST00000409189.7
C-C motif chemokine ligand 20
chr2_+_201132872 0.96 ENST00000470178.6
CASP8 and FADD like apoptosis regulator
chr2_-_207167220 0.91 ENST00000421199.5
ENST00000457962.5
Kruppel like factor 7
chr2_+_201132769 0.87 ENST00000494258.5
CASP8 and FADD like apoptosis regulator
chr2_+_201132928 0.85 ENST00000462763.5
CASP8 and FADD like apoptosis regulator
chr7_-_151057848 0.80 ENST00000297518.4
cyclin dependent kinase 5
chr7_-_151057880 0.80 ENST00000485972.6
cyclin dependent kinase 5
chr3_+_141384790 0.77 ENST00000507722.5
zinc finger and BTB domain containing 38
chr14_+_104138578 0.69 ENST00000423312.7
kinesin family member 26A
chr2_+_201132958 0.69 ENST00000479953.6
ENST00000340870.6
CASP8 and FADD like apoptosis regulator
chr11_-_72721908 0.62 ENST00000426523.5
ENST00000429686.5
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr3_+_112333147 0.62 ENST00000473539.5
ENST00000315711.12
ENST00000383681.7
CD200 molecule
chr4_+_41613476 0.58 ENST00000508466.1
LIM and calponin homology domains 1
chr6_-_39314412 0.52 ENST00000373231.9
potassium two pore domain channel subfamily K member 17
chr22_+_24607602 0.51 ENST00000447416.5
gamma-glutamyltransferase 1
chr6_-_39314445 0.50 ENST00000453413.2
potassium two pore domain channel subfamily K member 17
chr22_+_24607658 0.48 ENST00000451366.5
ENST00000428855.5
gamma-glutamyltransferase 1
chr6_-_30684744 0.41 ENST00000615892.4
protein phosphatase 1 regulatory subunit 18
chr2_+_209579429 0.40 ENST00000361559.8
microtubule associated protein 2
chr4_+_41612702 0.39 ENST00000509277.5
LIM and calponin homology domains 1
chr4_+_41612892 0.38 ENST00000509454.5
ENST00000396595.7
ENST00000381753.8
LIM and calponin homology domains 1
chr22_+_24607638 0.38 ENST00000432867.5
gamma-glutamyltransferase 1
chr5_-_151087131 0.35 ENST00000315050.11
ENST00000523338.5
ENST00000522100.5
TNFAIP3 interacting protein 1
chr3_-_15341368 0.35 ENST00000408919.7
SH3 domain binding protein 5
chr19_+_12751672 0.34 ENST00000549706.5
bestrophin 2
chr21_+_33229883 0.33 ENST00000382264.7
ENST00000342136.9
ENST00000404220.7
interferon alpha and beta receptor subunit 2
chr19_+_12751789 0.32 ENST00000553030.6
bestrophin 2
chr7_+_112450451 0.31 ENST00000429071.5
ENST00000403825.8
ENST00000675268.1
interferon related developmental regulator 1
novel protein
chrX_+_150363306 0.29 ENST00000370401.7
ENST00000432680.7
mastermind like domain containing 1
chrX_+_150363258 0.29 ENST00000683696.1
mastermind like domain containing 1
chr18_+_58045642 0.27 ENST00000676223.1
ENST00000675147.1
NEDD4 like E3 ubiquitin protein ligase
chr18_+_58045683 0.27 ENST00000592846.5
ENST00000675801.1
NEDD4 like E3 ubiquitin protein ligase
chr21_+_33230073 0.26 ENST00000342101.7
ENST00000413881.5
ENST00000443073.5
interferon alpha and beta receptor subunit 2
chr7_-_142258027 0.26 ENST00000552471.1
ENST00000547058.6
serine protease 58
chr20_+_836052 0.25 ENST00000246100.3
family with sequence similarity 110 member A
chr9_-_112332962 0.24 ENST00000458258.5
ENST00000210227.4
polypyrimidine tract binding protein 3
chr1_+_202122881 0.24 ENST00000683302.1
ENST00000683557.1
G protein-coupled receptor 37 like 1
chr11_+_72114840 0.24 ENST00000622388.4
folate receptor gamma
chr17_-_42028662 0.23 ENST00000461831.1
zinc finger protein 385C
chr10_+_97584347 0.22 ENST00000370649.3
ENST00000370646.9
novel protein
4-hydroxy-2-oxoglutarate aldolase 1
chr1_+_6206077 0.22 ENST00000377939.5
ring finger protein 207
chr4_-_25030922 0.22 ENST00000382114.9
leucine rich repeat LGI family member 2
chr1_+_61203496 0.22 ENST00000663597.1
nuclear factor I A
chr6_-_87095059 0.21 ENST00000369582.6
ENST00000610310.3
ENST00000630630.2
ENST00000627148.3
ENST00000625577.1
glycoprotein hormones, alpha polypeptide
chr5_+_36608146 0.21 ENST00000381918.4
ENST00000513646.1
solute carrier family 1 member 3
chr19_+_507487 0.21 ENST00000359315.6
tubulin polyglutamylase complex subunit 1
chr1_-_167914089 0.21 ENST00000476818.2
ENST00000367848.1
ENST00000367851.9
ENST00000545172.5
adenylate cyclase 10
chr10_+_116590956 0.20 ENST00000358834.9
ENST00000528052.5
pancreatic lipase related protein 1
chr10_+_116591010 0.20 ENST00000530319.5
ENST00000527980.5
ENST00000471549.5
ENST00000534537.5
pancreatic lipase related protein 1
chr17_-_8210203 0.20 ENST00000578549.5
ENST00000582368.5
aurora kinase B
chrX_+_15749848 0.20 ENST00000479740.5
ENST00000454127.2
carbonic anhydrase 5B
chr10_+_80537902 0.19 ENST00000339284.6
ENST00000646907.2
SH2 domain containing 4B
chr1_-_52404387 0.19 ENST00000371566.1
ENST00000371568.8
origin recognition complex subunit 1
chr11_-_19202004 0.19 ENST00000648719.1
cysteine and glycine rich protein 3
chr12_+_49323236 0.19 ENST00000549275.5
ENST00000551245.5
ENST00000380327.9
ENST00000548311.5
ENST00000257909.8
ENST00000550346.5
ENST00000550709.5
ENST00000549534.1
ENST00000547807.5
ENST00000551567.1
trophinin associated protein
chr12_+_49295138 0.19 ENST00000257860.9
peripherin
chr20_-_57710539 0.18 ENST00000395816.7
ENST00000347215.8
prostate transmembrane protein, androgen induced 1
chr14_+_21030509 0.18 ENST00000481535.5
tubulin polymerization promoting protein family member 2
chr7_+_111091119 0.18 ENST00000308478.10
leucine rich repeat neuronal 3
chr18_+_12308232 0.18 ENST00000590103.5
ENST00000591909.5
ENST00000586653.5
ENST00000317702.10
ENST00000592683.5
ENST00000590967.5
ENST00000591208.1
ENST00000591463.1
tubulin beta 6 class V
chr17_+_38428456 0.17 ENST00000622683.5
ENST00000620417.4
Rho GTPase activating protein 23
chr7_+_111091006 0.16 ENST00000451085.5
ENST00000422987.3
ENST00000421101.1
leucine rich repeat neuronal 3
chr12_-_10802627 0.16 ENST00000240687.2
taste 2 receptor member 7
chr6_+_44223770 0.15 ENST00000652453.1
ENST00000393841.6
ENST00000371724.6
ENST00000642777.1
ENST00000645692.1
solute carrier family 29 member 1 (Augustine blood group)
chr14_-_74426102 0.15 ENST00000554953.1
ENST00000331628.8
synapse differentiation inducing 1 like
chr17_+_47831608 0.14 ENST00000269025.9
leucine rich repeat containing 46
chr14_-_68793055 0.14 ENST00000439696.3
ZFP36 ring finger protein like 1
chr14_-_64942720 0.14 ENST00000557049.1
ENST00000389614.6
glutathione peroxidase 2
chr14_+_96256194 0.14 ENST00000216629.11
ENST00000553356.1
bradykinin receptor B1
chr7_-_81770122 0.14 ENST00000423064.7
hepatocyte growth factor
chr9_+_35042213 0.13 ENST00000378745.3
ENST00000312292.6
chromosome 9 open reading frame 131
chr2_+_203867764 0.13 ENST00000648405.2
cytotoxic T-lymphocyte associated protein 4
chr4_-_103019634 0.12 ENST00000510559.1
ENST00000296422.12
ENST00000394789.7
solute carrier family 9 member B1
chr6_+_133889105 0.12 ENST00000367882.5
transcription factor 21
chr4_-_40630588 0.12 ENST00000514014.1
RNA binding motif protein 47
chr20_+_142573 0.12 ENST00000382398.4
defensin beta 126
chr20_-_3786677 0.12 ENST00000379751.5
centromere protein B
chr14_-_64942783 0.12 ENST00000612794.1
glutathione peroxidase 2
chr6_-_53148822 0.11 ENST00000259803.8
glial cells missing transcription factor 1
chrX_-_134796256 0.11 ENST00000486347.5
PABIR family member 2
chr19_+_38304105 0.11 ENST00000588605.5
ENST00000301246.10
chromosome 19 open reading frame 33
chr1_-_110064916 0.11 ENST00000649954.1
ALX homeobox 3
chr7_-_20217342 0.11 ENST00000400331.10
ENST00000332878.8
MET transcriptional regulator MACC1
chr14_+_73616844 0.11 ENST00000381139.1
acyl-CoA thioesterase 6
chr15_-_89679360 0.11 ENST00000300055.10
perilipin 1
chr15_-_89679411 0.11 ENST00000430628.2
perilipin 1
chr3_-_9769910 0.10 ENST00000256460.8
calcium/calmodulin dependent protein kinase I
chr5_+_168486462 0.10 ENST00000231572.8
ENST00000626454.1
arginyl-tRNA synthetase 1
chr10_+_5048748 0.10 ENST00000602997.5
ENST00000439082.7
aldo-keto reductase family 1 member C3
chr9_+_122614738 0.10 ENST00000297913.3
olfactory receptor family 1 subfamily Q member 1
chr20_+_59721210 0.10 ENST00000395636.6
ENST00000361300.4
phosphatase and actin regulator 3
chr11_-_102625332 0.10 ENST00000260228.3
matrix metallopeptidase 20
chr19_-_10102659 0.10 ENST00000592641.5
ENST00000253109.5
angiopoietin like 6
chr11_+_118956289 0.09 ENST00000264031.3
uroplakin 2
chr17_+_39628496 0.09 ENST00000394265.5
ENST00000394267.2
protein phosphatase 1 regulatory inhibitor subunit 1B
chr22_+_24603147 0.09 ENST00000412658.5
ENST00000445029.5
ENST00000400382.6
ENST00000419133.5
ENST00000438643.6
ENST00000452551.5
ENST00000412898.5
ENST00000400380.5
ENST00000455483.5
ENST00000430289.5
gamma-glutamyltransferase 1
chr19_+_4304588 0.09 ENST00000221856.11
fibronectin type III and SPRY domain containing 1
chr8_+_78516329 0.09 ENST00000396418.7
ENST00000352966.9
cAMP-dependent protein kinase inhibitor alpha
chr3_+_51861604 0.09 ENST00000333127.4
IQ motif containing F2
chr10_-_102451536 0.08 ENST00000625129.1
chromosome 10 open reading frame 95
chr16_-_30031259 0.08 ENST00000380495.8
TLC domain containing 3B
chr1_+_27934980 0.08 ENST00000373894.8
sphingomyelin phosphodiesterase acid like 3B
chr11_-_63563370 0.07 ENST00000255695.2
phospholipase A and acyltransferase 2
chr6_+_11093753 0.07 ENST00000416247.4
small integral membrane protein 13
chr17_+_6444441 0.07 ENST00000250056.12
ENST00000571373.5
ENST00000570337.6
ENST00000572595.6
ENST00000572447.6
ENST00000576056.5
PICALM interacting mitotic regulator
chr6_+_43132472 0.07 ENST00000489707.5
protein tyrosine kinase 7 (inactive)
chrX_+_71144818 0.07 ENST00000536169.5
ENST00000358741.4
ENST00000395855.6
ENST00000374051.7
neuroligin 3
chr1_+_27935110 0.07 ENST00000549094.1
sphingomyelin phosphodiesterase acid like 3B
chr11_+_125063295 0.06 ENST00000532000.5
ENST00000403796.7
ENST00000308074.4
solute carrier family 37 member 2
chrX_+_47190836 0.06 ENST00000377351.8
ubiquitin like modifier activating enzyme 1
chr12_+_40692413 0.06 ENST00000551295.7
ENST00000547702.5
ENST00000551424.5
contactin 1
chr16_+_67893244 0.06 ENST00000291041.6
ENST00000570631.5
protein serine kinase H1
chr2_-_27495185 0.06 ENST00000264703.4
fibronectin type III domain containing 4
chr19_+_17075767 0.06 ENST00000682292.1
ENST00000595618.5
ENST00000594824.5
myosin IXB
chr19_+_35868585 0.06 ENST00000652533.1
amyloid beta precursor like protein 1
chr11_+_67403887 0.06 ENST00000526387.5
TBC1 domain family member 10C
chr16_+_56935371 0.06 ENST00000568358.1
homocysteine inducible ER protein with ubiquitin like domain 1
chr11_+_67404077 0.06 ENST00000542590.2
ENST00000312390.9
TBC1 domain family member 10C
chr12_+_53454819 0.06 ENST00000562264.5
poly(rC) binding protein 2
chr17_-_63704388 0.06 ENST00000582026.2
STE20 related adaptor alpha
chr12_+_53454764 0.05 ENST00000439930.7
ENST00000548933.5
poly(rC) binding protein 2
chr12_-_53336342 0.05 ENST00000537210.2
ENST00000536324.4
Sp7 transcription factor
chr12_-_7109176 0.05 ENST00000545280.5
ENST00000543933.5
ENST00000545337.1
ENST00000266542.9
ENST00000544702.5
complement C1r subcomponent like
chr11_-_5243644 0.05 ENST00000643122.1
hemoglobin subunit delta
chr9_-_97938157 0.05 ENST00000616898.2
hemogen
chr6_+_101181254 0.05 ENST00000682090.1
ENST00000421544.6
glutamate ionotropic receptor kainate type subunit 2
chr19_+_35868518 0.05 ENST00000221891.9
amyloid beta precursor like protein 1
chr2_-_42361198 0.05 ENST00000234301.3
cytochrome c oxidase subunit 7A2 like
chr13_-_60013178 0.05 ENST00000498416.2
ENST00000465066.5
diaphanous related formin 3
chr1_+_45012691 0.05 ENST00000469548.5
uroporphyrinogen decarboxylase
chr1_+_45012896 0.04 ENST00000428106.1
uroporphyrinogen decarboxylase
chr10_+_101354083 0.04 ENST00000408038.6
ENST00000370187.8
beta-transducin repeat containing E3 ubiquitin protein ligase
chr16_+_6019585 0.04 ENST00000547372.5
RNA binding fox-1 homolog 1
chr2_+_203867943 0.04 ENST00000295854.10
ENST00000487393.1
ENST00000472206.1
cytotoxic T-lymphocyte associated protein 4
chr3_+_112332500 0.04 ENST00000606471.5
CD200 molecule
chr14_+_23953729 0.04 ENST00000558263.5
ENST00000543741.6
ENST00000313250.10
ENST00000397075.7
ENST00000397074.7
ENST00000559632.5
ENST00000558581.5
dehydrogenase/reductase 4
chrX_+_50067576 0.04 ENST00000376108.7
chloride voltage-gated channel 5
chr2_+_97646034 0.03 ENST00000258424.3
cytochrome c oxidase subunit 5B
chr1_+_27935022 0.03 ENST00000411604.5
ENST00000373888.8
sphingomyelin phosphodiesterase acid like 3B
chr19_+_55488404 0.03 ENST00000594321.5
ENST00000389623.11
scavenger receptor cysteine rich family member with 5 domains
chr18_+_7567266 0.03 ENST00000580170.6
protein tyrosine phosphatase receptor type M
chr3_-_49093578 0.03 ENST00000424300.5
glutamine rich 1
chr16_+_89490917 0.03 ENST00000647079.1
SPG7 matrix AAA peptidase subunit, paraplegin
chr7_-_141014629 0.03 ENST00000393008.7
mitochondrial ribosomal protein S33
chr3_+_124094663 0.03 ENST00000460856.5
ENST00000240874.7
kalirin RhoGEF kinase
chr12_-_52814106 0.03 ENST00000551956.2
keratin 4
chr12_-_53335737 0.02 ENST00000303846.3
Sp7 transcription factor
chr10_+_97584314 0.02 ENST00000370647.8
4-hydroxy-2-oxoglutarate aldolase 1
chr7_-_141014939 0.02 ENST00000324787.10
ENST00000467334.1
mitochondrial ribosomal protein S33
chr6_-_132798587 0.02 ENST00000275227.9
solute carrier family 18 member B1
chr15_+_68277724 0.02 ENST00000306917.5
fem-1 homolog B
chr10_-_116273606 0.02 ENST00000682743.1
GDNF family receptor alpha 1
chr16_+_90022600 0.02 ENST00000620723.4
ENST00000268699.9
growth arrest specific 8
chr6_-_36986122 0.02 ENST00000460219.2
ENST00000373627.10
ENST00000373616.9
mitochondrial carrier 1
chr3_+_15601736 0.02 ENST00000303498.10
ENST00000417015.3
ENST00000672065.1
ENST00000672112.1
ENST00000643237.3
ENST00000672141.1
ENST00000646371.1
ENST00000672427.1
ENST00000672336.1
ENST00000673467.1
ENST00000672760.1
ENST00000437172.6
biotinidase
chr15_-_78811415 0.02 ENST00000388820.5
ADAM metallopeptidase with thrombospondin type 1 motif 7
chr11_+_2302119 0.01 ENST00000381121.7
tetraspanin 32
chr10_+_101354028 0.01 ENST00000393441.8
beta-transducin repeat containing E3 ubiquitin protein ligase
chr19_-_12933680 0.01 ENST00000593021.1
ENST00000314606.9
ENST00000587981.1
ENST00000423140.6
phenylalanyl-tRNA synthetase subunit alpha
chr5_+_144205250 0.01 ENST00000507359.3
potassium channel tetramerization domain containing 16
chr17_+_7933080 0.01 ENST00000565740.5
centrobin, centriole duplication and spindle assembly protein
chr7_+_100219236 0.01 ENST00000317271.2
PVR related immunoglobulin domain containing
chr17_-_76551174 0.01 ENST00000589145.1
cytoglobin
chr10_+_125973373 0.01 ENST00000417114.5
ENST00000445510.5
ENST00000368691.5
fibronectin type III and ankyrin repeat domains 1
chr2_+_230996115 0.00 ENST00000424440.5
ENST00000452881.5
ENST00000433428.6
ENST00000455816.1
ENST00000440792.5
ENST00000423134.1
spermatogenesis associated 3
chr12_-_68253502 0.00 ENST00000328087.6
ENST00000538666.6
interleukin 22
chr7_+_76510516 0.00 ENST00000257632.9
uroplakin 3B
chr12_-_25648544 0.00 ENST00000540106.5
ENST00000445693.5
ENST00000545543.1
lamin tail domain containing 1
chr12_+_25958891 0.00 ENST00000381352.7
ENST00000535907.5
ENST00000405154.6
ENST00000615708.4
Ras association domain family member 8
chr13_-_41019289 0.00 ENST00000239882.7
E74 like ETS transcription factor 1
chr1_+_1281224 0.00 ENST00000400928.7
sodium channel epithelial 1 subunit delta

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.3 3.4 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.2 0.7 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.2 1.6 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 0.6 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 0.3 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 1.5 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.1 0.3 GO:0007518 myoblast fate determination(GO:0007518)
0.1 0.2 GO:1903947 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of atrial cardiac muscle cell action potential(GO:1903949) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.1 0.2 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.0 0.1 GO:1904582 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.0 0.5 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 1.0 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0072277 branchiomeric skeletal muscle development(GO:0014707) bronchiole development(GO:0060435) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.0 0.2 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.7 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.2 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.1 GO:0016487 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.2 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.2 GO:0006537 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.2 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.6 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.2 GO:0015884 folic acid transport(GO:0015884)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 3.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.5 1.6 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.1 0.6 GO:0004905 type I interferon receptor activity(GO:0004905)
0.1 3.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 1.5 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.2 GO:0036505 prosaposin receptor activity(GO:0036505)
0.0 1.0 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0031696 alpha-2C adrenergic receptor binding(GO:0031696)
0.0 0.2 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.1 GO:0047787 geranylgeranyl reductase activity(GO:0045550) delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.0 0.6 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.0 0.5 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.2 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696) centromeric DNA binding(GO:0019237)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433)
0.0 0.0 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.2 GO:0005542 folic acid binding(GO:0005542)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.0 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 2.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.5 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide