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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for HBP1

Z-value: 1.31

Motif logo

Transcription factors associated with HBP1

Gene Symbol Gene ID Gene Info
ENSG00000105856.14 HBP1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HBP1hg38_v1_chr7_+_107168961_107169010-0.871.1e-08Click!

Activity profile of HBP1 motif

Sorted Z-values of HBP1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HBP1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_-_44265541 6.31 ENST00000619360.6
NFKB inhibitor epsilon
chr3_-_127736329 5.76 ENST00000398101.7
monoglyceride lipase
chr3_+_72888031 4.64 ENST00000389617.9
glucoside xylosyltransferase 2
chr7_-_93148345 3.99 ENST00000437805.5
ENST00000446959.5
ENST00000439952.5
ENST00000414791.5
ENST00000446033.1
ENST00000411955.5
ENST00000318238.9
sterile alpha motif domain containing 9 like
chr12_-_89526253 3.99 ENST00000547474.1
POC1B-GALNT4 readthrough
chr12_-_89526164 3.90 ENST00000548729.5
POC1B-GALNT4 readthrough
chr2_-_219399981 3.79 ENST00000519905.1
ENST00000523282.5
ENST00000434339.5
ENST00000457935.5
aspartyl aminopeptidase
chr1_+_65147514 3.74 ENST00000545314.5
adenylate kinase 4
chr1_+_65147657 3.72 ENST00000546702.5
adenylate kinase 4
chr4_+_85604146 3.48 ENST00000512201.5
Rho GTPase activating protein 24
chr10_+_24239181 2.93 ENST00000438429.5
KIAA1217
chr11_+_73376365 2.82 ENST00000064780.7
ENST00000545687.5
RELT TNF receptor
chr11_+_35186820 2.64 ENST00000531110.6
ENST00000525685.6
CD44 molecule (Indian blood group)
chr1_-_46616804 2.60 ENST00000531769.6
ENST00000319928.8
MAPK interacting serine/threonine kinase 1
MOB kinase activator 3C
chr11_+_20022550 2.58 ENST00000533917.5
neuron navigator 2
chr2_+_64989343 2.48 ENST00000234256.4
solute carrier family 1 member 4
chr7_+_18496162 2.38 ENST00000406072.5
histone deacetylase 9
chr5_+_126423122 2.36 ENST00000515200.5
GRAM domain containing 2B
chr9_+_130200375 2.34 ENST00000630865.1
neuronal calcium sensor 1
chr9_+_130172343 2.30 ENST00000372398.6
neuronal calcium sensor 1
chr7_-_105679089 2.28 ENST00000477775.5
ataxin 7 like 1
chr10_+_110005804 2.24 ENST00000360162.7
adducin 3
chr7_-_2314365 2.21 ENST00000222990.8
sorting nexin 8
chr2_+_74198605 2.20 ENST00000409804.5
ENST00000678340.1
ENST00000679055.1
ENST00000394053.7
ENST00000409601.1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr3_+_112086335 2.18 ENST00000431717.6
ENST00000480282.5
chromosome 3 open reading frame 52
chr20_+_46894824 2.18 ENST00000327619.10
ENST00000497062.6
EYA transcriptional coactivator and phosphatase 2
chr19_-_18397596 2.17 ENST00000595840.1
ENST00000339007.4
leucine rich repeat containing 25
chr3_+_112086364 2.15 ENST00000264848.10
chromosome 3 open reading frame 52
chr4_+_5051471 2.14 ENST00000282908.10
serine/threonine kinase 32B
chr17_-_50129792 2.12 ENST00000503131.1
sterile alpha motif domain containing 14
chr15_+_74782069 2.08 ENST00000220003.14
ENST00000439220.6
C-terminal Src kinase
chr20_+_46894581 2.05 ENST00000357410.7
ENST00000611592.4
EYA transcriptional coactivator and phosphatase 2
chr2_+_218568865 1.90 ENST00000295701.9
CCR4-NOT transcription complex subunit 9
chr12_-_89526011 1.90 ENST00000313546.8
POC1 centriolar protein B
chr6_-_36024635 1.90 ENST00000490799.6
solute carrier family 26 member 8
chr3_-_146161167 1.85 ENST00000360060.7
ENST00000282903.10
procollagen-lysine,2-oxoglutarate 5-dioxygenase 2
chr1_+_111230725 1.78 ENST00000533831.6
chitinase 3 like 2
chr4_+_139015751 1.78 ENST00000280614.4
nocturnin
chr17_-_50130121 1.77 ENST00000330175.9
sterile alpha motif domain containing 14
chr6_-_36024493 1.74 ENST00000394602.6
ENST00000355574.6
solute carrier family 26 member 8
chr11_+_94543894 1.71 ENST00000358752.4
fucosyltransferase 4
chr22_-_30246739 1.67 ENST00000403987.3
ENST00000249075.4
LIF interleukin 6 family cytokine
chr17_-_41009124 1.65 ENST00000391588.3
keratin associated protein 3-1
chr10_-_58267868 1.64 ENST00000373935.4
inositol polyphosphate multikinase
chr6_+_29100609 1.64 ENST00000377171.3
olfactory receptor family 2 subfamily J member 1
chr20_+_33217325 1.63 ENST00000375452.3
ENST00000375454.8
BPI fold containing family A member 3
chr17_-_1491610 1.61 ENST00000646049.1
myosin IC
chr18_+_34709356 1.57 ENST00000585446.1
ENST00000681241.1
dystrobrevin alpha
chr22_-_17773976 1.56 ENST00000317361.11
BH3 interacting domain death agonist
chr18_+_58362467 1.54 ENST00000675101.1
NEDD4 like E3 ubiquitin protein ligase
chr11_-_65900375 1.47 ENST00000312562.7
FOS like 1, AP-1 transcription factor subunit
chr11_-_65900413 1.45 ENST00000448083.6
ENST00000531493.5
ENST00000532401.1
FOS like 1, AP-1 transcription factor subunit
chr4_-_118836067 1.39 ENST00000280551.11
SEC24 homolog D, COPII coat complex component
chr3_+_100709424 1.38 ENST00000675246.1
ENST00000675692.1
ENST00000675890.1
ENST00000675586.1
ENST00000674645.1
ENST00000675958.1
ENST00000479672.6
ENST00000675420.1
ENST00000674615.1
ENST00000676431.1
ENST00000674758.1
trafficking from ER to golgi regulator
chr3_+_100709382 1.38 ENST00000620299.5
trafficking from ER to golgi regulator
chr19_+_38899680 1.35 ENST00000576510.5
ENST00000392079.7
NFKB inhibitor beta
chr4_+_99574812 1.35 ENST00000422897.6
ENST00000265517.10
microsomal triglyceride transfer protein
chr19_+_48552159 1.32 ENST00000201586.7
sulfotransferase family 2B member 1
chr4_-_48016631 1.31 ENST00000513178.2
ENST00000514170.7
cyclic nucleotide gated channel subunit alpha 1
chr3_+_100709344 1.30 ENST00000418917.7
ENST00000675553.1
trafficking from ER to golgi regulator
chr1_-_247760556 1.30 ENST00000641256.1
olfactory receptor family 1 subfamily C member 1
chr8_-_8893548 1.28 ENST00000276282.7
malignant fibrous histiocytoma amplified sequence 1
chr12_+_21501780 1.26 ENST00000229314.10
ENST00000542038.5
ENST00000540141.5
ENST00000631252.2
golgi transport 1B
chr6_+_29587455 1.26 ENST00000383640.4
olfactory receptor family 2 subfamily H member 2
chr3_+_100709473 1.25 ENST00000240851.9
ENST00000675243.1
ENST00000676111.1
ENST00000476228.5
ENST00000463568.6
ENST00000676395.1
trafficking from ER to golgi regulator
chr21_+_43719095 1.22 ENST00000468090.5
ENST00000291565.9
pyridoxal kinase
chr9_-_35563867 1.19 ENST00000399742.7
ENST00000619051.4
family with sequence similarity 166 member B
chr17_+_4950147 1.19 ENST00000522301.5
enolase 3
chr19_+_38899946 1.18 ENST00000572515.5
ENST00000313582.6
ENST00000575359.5
NFKB inhibitor beta
chr3_+_100709290 1.18 ENST00000675047.1
ENST00000490574.6
ENST00000675543.1
ENST00000676308.1
ENST00000675499.1
trafficking from ER to golgi regulator
chr15_-_66356672 1.14 ENST00000261881.9
TIMELESS interacting protein
chr4_-_47981535 1.12 ENST00000402813.9
cyclic nucleotide gated channel subunit alpha 1
chr6_+_30647008 1.12 ENST00000293604.10
ENST00000376473.9
chromosome 6 open reading frame 136
chr19_+_17719471 1.11 ENST00000600186.5
ENST00000597735.5
ENST00000324096.9
microtubule associated protein 1S
chr12_-_99154492 1.11 ENST00000546568.5
ENST00000546960.5
ankyrin repeat and sterile alpha motif domain containing 1B
chr2_-_238288600 1.07 ENST00000254657.8
period circadian regulator 2
chr15_+_33968484 1.07 ENST00000383263.7
cholinergic receptor muscarinic 5
chr11_+_69294107 1.05 ENST00000441339.3
ENST00000308946.3
ENST00000535407.1
myeloma overexpressed
chr2_-_223837484 1.05 ENST00000446015.6
ENST00000409375.1
adaptor related protein complex 1 subunit sigma 3
chr1_+_43969970 1.05 ENST00000255108.8
ENST00000396758.6
diphthamide biosynthesis 2
chr3_+_141051339 1.04 ENST00000310546.3
splA/ryanodine receptor domain and SOCS box containing 4
chr11_+_64035925 1.03 ENST00000682287.1
fibronectin leucine rich transmembrane protein 1
chr16_-_695946 1.02 ENST00000562563.1
F-box and leucine rich repeat protein 16
chr11_+_67416086 1.01 ENST00000445895.2
carnosine synthase 1
chr1_+_85062304 0.98 ENST00000326813.12
ENST00000528899.5
ENST00000294664.11
dynein axonemal intermediate chain 3
chr20_-_49713842 0.96 ENST00000371711.4
beta-1,4-galactosyltransferase 5
chr7_-_75813799 0.96 ENST00000222902.7
C-C motif chemokine ligand 24
chr17_-_44066595 0.96 ENST00000585388.2
ENST00000293406.8
LSM12 homolog
chr6_+_30647109 0.95 ENST00000651131.1
ENST00000376471.8
chromosome 6 open reading frame 136
chr14_-_100587404 0.95 ENST00000554140.2
brain enriched guanylate kinase associated
chrX_+_153334146 0.94 ENST00000370249.3
ENST00000650114.2
ENST00000370251.3
zinc finger protein 275
chr4_+_158315309 0.93 ENST00000460056.6
relaxin family peptide receptor 1
chr2_+_207711534 0.90 ENST00000392209.7
cyclin Y like 1
chr2_+_218568809 0.90 ENST00000273064.11
CCR4-NOT transcription complex subunit 9
chr17_+_81666713 0.89 ENST00000329214.13
ENST00000574107.1
coiled-coil domain containing 137
chr17_+_42798857 0.88 ENST00000588408.6
cyclin N-terminal domain containing 1
chr17_-_43778937 0.87 ENST00000226004.8
dual specificity phosphatase 3
chr6_+_157981826 0.86 ENST00000355585.9
ENST00000640338.1
ENST00000367113.5
synaptojanin 2
chr11_+_43680772 0.85 ENST00000395700.4
ENST00000637401.1
hydroxysteroid 17-beta dehydrogenase 12
chr10_-_132942526 0.84 ENST00000368586.10
cilia and flagella associated protein 46
chr3_-_52056552 0.84 ENST00000495880.2
dual specificity phosphatase 7
chr16_+_11668414 0.82 ENST00000329565.6
stannin
chr5_+_140691427 0.81 ENST00000643996.1
ENST00000509299.6
ENST00000645065.1
ENST00000642752.1
ENST00000503873.6
ENST00000642970.1
ENST00000230771.9
ENST00000646468.1
ENST00000645749.1
histidyl-tRNA synthetase 2, mitochondrial
chr2_-_29921580 0.80 ENST00000389048.8
ALK receptor tyrosine kinase
chr19_+_34365173 0.78 ENST00000589640.5
ENST00000591204.5
ENST00000589399.6
ENST00000356487.11
glucose-6-phosphate isomerase
chr16_+_31355215 0.77 ENST00000562522.2
integrin subunit alpha X
chr19_-_55580829 0.75 ENST00000592239.1
ENST00000325421.7
zinc finger protein 579
chr21_+_33230073 0.75 ENST00000342101.7
ENST00000413881.5
ENST00000443073.5
interferon alpha and beta receptor subunit 2
chr21_+_33229883 0.74 ENST00000382264.7
ENST00000342136.9
ENST00000404220.7
interferon alpha and beta receptor subunit 2
chr2_-_223837553 0.73 ENST00000396654.7
ENST00000396653.2
ENST00000443700.5
adaptor related protein complex 1 subunit sigma 3
chr7_+_66075811 0.72 ENST00000304874.14
ENST00000673518.1
ENST00000380839.9
argininosuccinate lyase
chr2_+_207711631 0.72 ENST00000295414.8
ENST00000420822.1
ENST00000339882.9
cyclin Y like 1
chr12_-_57752345 0.72 ENST00000551800.5
ENST00000549606.5
ENST00000312990.10
cyclin dependent kinase 4
chr11_+_119334511 0.71 ENST00000311413.5
ring finger protein 26
chr3_+_133805789 0.70 ENST00000678299.1
SRP receptor subunit beta
chr4_+_26320975 0.69 ENST00000509158.6
ENST00000681856.1
ENST00000680140.1
ENST00000355476.8
ENST00000680511.1
recombination signal binding protein for immunoglobulin kappa J region
chr19_+_18683656 0.69 ENST00000338797.10
ENST00000321949.13
CREB regulated transcription coactivator 1
chr1_-_154183130 0.68 ENST00000368531.6
ENST00000368533.8
tropomyosin 3
chr17_-_38748184 0.68 ENST00000618941.4
ENST00000620225.5
ENST00000618506.1
ENST00000616129.4
polycomb group ring finger 2
chr19_-_45153852 0.68 ENST00000589776.1
NTPase KAP family P-loop domain containing 1
chr8_-_11868043 0.67 ENST00000676843.1
ENST00000534510.6
ENST00000676825.1
ENST00000678145.1
ENST00000533455.6
ENST00000353047.11
ENST00000677650.1
ENST00000526195.6
ENST00000676691.1
ENST00000678598.1
ENST00000505496.7
ENST00000527215.7
ENST00000345125.8
ENST00000532656.7
ENST00000678067.1
ENST00000453527.7
ENST00000677415.1
ENST00000530640.7
ENST00000677418.1
ENST00000531089.6
ENST00000677544.1
ENST00000676502.1
ENST00000524500.6
ENST00000677873.1
ENST00000678629.1
ENST00000678929.1
ENST00000677819.1
ENST00000678357.1
ENST00000679051.1
ENST00000677082.1
ENST00000531502.6
ENST00000530296.6
ENST00000534636.6
ENST00000534149.6
ENST00000677366.1
ENST00000676755.1
ENST00000679140.1
ENST00000527243.6
ENST00000677047.1
ENST00000678242.1
cathepsin B
chr11_-_7830840 0.67 ENST00000641167.1
olfactory receptor family 5 subfamily P member 3
chr1_+_13171848 0.67 ENST00000415919.3
PRAME family member 9
chr17_+_42798881 0.66 ENST00000588527.5
cyclin N-terminal domain containing 1
chr7_+_66075913 0.66 ENST00000362000.10
ENST00000395331.4
ENST00000671817.1
argininosuccinate lyase
chr19_+_34365240 0.66 ENST00000586425.2
glucose-6-phosphate isomerase
chr7_+_66075876 0.65 ENST00000395332.8
argininosuccinate lyase
chr14_+_101964561 0.64 ENST00000643508.2
ENST00000680137.1
ENST00000644881.2
ENST00000645149.2
ENST00000681574.1
ENST00000360184.10
ENST00000679720.1
ENST00000645114.2
dynein cytoplasmic 1 heavy chain 1
chr19_+_19033575 0.63 ENST00000392335.6
ENST00000537263.5
ENST00000540707.5
ENST00000535612.6
ENST00000541725.5
ENST00000269932.10
ENST00000546344.5
ENST00000540792.5
ENST00000536098.5
ENST00000541898.5
armadillo repeat containing 6
chr20_+_45857607 0.63 ENST00000255152.3
zinc finger SWIM-type containing 3
chr4_+_121801311 0.62 ENST00000379663.7
ENST00000243498.10
ENST00000509800.5
exosome component 9
chr19_+_38647614 0.62 ENST00000252699.7
ENST00000424234.7
ENST00000440400.2
actinin alpha 4
chr5_-_16465757 0.62 ENST00000308683.3
zinc finger protein 622
chr20_-_23986795 0.62 ENST00000286890.8
ENST00000278765.8
gamma-glutamyltransferase light chain 1
chr19_+_38647679 0.61 ENST00000390009.7
ENST00000589528.1
actinin alpha 4
chr4_-_122621011 0.61 ENST00000611104.2
ENST00000648588.1
interleukin 21
chr15_+_57591891 0.60 ENST00000267853.10
ENST00000380569.6
myocardial zonula adherens protein
GRINL1A complex locus 1
chr9_-_125484490 0.60 ENST00000444226.1
MAPK associated protein 1
chr8_+_94641074 0.58 ENST00000423620.6
epithelial splicing regulatory protein 1
chr4_+_26320782 0.58 ENST00000514807.5
ENST00000348160.9
recombination signal binding protein for immunoglobulin kappa J region
chr6_-_36874783 0.57 ENST00000373699.6
peptidylprolyl isomerase like 1
chrX_+_150983350 0.57 ENST00000455596.5
ENST00000448905.6
high mobility group box 3
chr6_+_42563981 0.57 ENST00000372899.6
ENST00000372901.2
ubiquitin protein ligase E3 component n-recognin 2
chr2_+_231037500 0.56 ENST00000373640.5
chromosome 2 open reading frame 72
chr6_-_30672984 0.56 ENST00000415603.1
ENST00000376442.8
DEAH-box helicase 16
chr2_-_68952880 0.56 ENST00000481498.1
ENST00000328895.9
gastrokine 2
chr3_+_5122276 0.56 ENST00000256496.8
ENST00000419534.2
ADP ribosylation factor like GTPase 8B
chr5_-_140691312 0.56 ENST00000438307.6
ENST00000415192.6
ENST00000509087.2
ENST00000675698.1
ENST00000504156.7
ENST00000457527.6
ENST00000307633.7
ENST00000676327.1
ENST00000675851.1
ENST00000675366.1
ENST00000675204.1
ENST00000507746.7
ENST00000431330.7
histidyl-tRNA synthetase 1
chr7_-_151024423 0.56 ENST00000469530.4
ENST00000639579.1
autophagy related 9B
chr7_+_117480011 0.56 ENST00000649406.1
ENST00000648260.1
ENST00000003084.11
CF transmembrane conductance regulator
chr3_+_46370854 0.55 ENST00000292303.4
C-C motif chemokine receptor 5
chr12_+_55362975 0.54 ENST00000641576.1
olfactory receptor family 6 subfamily C member 75
chr4_+_26320563 0.54 ENST00000361572.10
recombination signal binding protein for immunoglobulin kappa J region
chr6_+_42564060 0.53 ENST00000372903.6
ubiquitin protein ligase E3 component n-recognin 2
chr8_-_115492221 0.51 ENST00000518018.1
transcriptional repressor GATA binding 1
chr15_+_57592003 0.50 ENST00000587652.5
ENST00000649429.1
ENST00000380568.7
ENST00000380565.8
GRINL1A complex locus 1
myocardial zonula adherens protein
chr20_-_31475125 0.50 ENST00000317676.3
defensin beta 124
chr19_-_51531659 0.50 ENST00000425629.8
sialic acid binding Ig like lectin 6
chr16_-_3611577 0.50 ENST00000294008.4
SLX4 structure-specific endonuclease subunit
chr1_-_154183199 0.49 ENST00000323144.12
ENST00000330188.13
ENST00000328159.9
ENST00000611659.4
tropomyosin 3
chr7_-_149461056 0.48 ENST00000247930.5
zinc finger protein 777
chr20_+_25195664 0.48 ENST00000354989.9
ENST00000360031.6
ENST00000376652.9
ENST00000439162.5
ENST00000433417.5
ENST00000417467.5
ENST00000433259.6
ENST00000427553.5
ectonucleoside triphosphate diphosphohydrolase 6
chrX_-_13319952 0.47 ENST00000622204.1
ENST00000380622.5
ataxin 3 like
chr5_+_162067500 0.45 ENST00000639384.1
ENST00000640985.1
ENST00000638772.1
gamma-aminobutyric acid type A receptor subunit gamma2
chr22_+_20117734 0.44 ENST00000416427.5
ENST00000421656.5
ENST00000423859.5
ENST00000418705.2
RAN binding protein 1
chr1_-_52698320 0.44 ENST00000371538.5
cytochrome c oxidase assembly factor 7
chr16_-_89418292 0.44 ENST00000683497.1
ENST00000642443.1
ENST00000644784.1
ENST00000647238.1
novel protein
ankyrin repeat domain 11
chr10_-_118342240 0.44 ENST00000369170.4
family with sequence similarity 204 member A
chr11_-_66958366 0.43 ENST00000651036.1
ENST00000652125.1
ENST00000531614.6
ENST00000524491.6
ENST00000529047.6
ENST00000393960.7
ENST00000393958.7
ENST00000528403.6
ENST00000651854.1
pyruvate carboxylase
chr5_+_162067458 0.42 ENST00000639975.1
ENST00000639111.2
ENST00000639683.1
gamma-aminobutyric acid type A receptor subunit gamma2
chr5_-_79514127 0.42 ENST00000334082.11
homer scaffold protein 1
chr7_+_141551278 0.42 ENST00000629555.2
ENST00000473247.5
ENST00000648690.1
ENST00000649286.2
ENST00000649914.1
ENST00000648395.1
ENST00000648068.1
ENST00000650547.1
acylglycerol kinase
chr3_-_186570308 0.42 ENST00000446782.5
TBCC domain containing 1
chr2_-_112836702 0.41 ENST00000416750.1
ENST00000263341.7
ENST00000418817.5
interleukin 1 beta
chr5_+_150660841 0.41 ENST00000297130.4
myozenin 3
chr3_+_191329020 0.41 ENST00000392456.4
coiled-coil domain containing 50
chr12_+_123633739 0.40 ENST00000618160.4
general transcription factor IIH subunit 3
chrX_-_23907887 0.40 ENST00000379226.9
apolipoprotein O
chrX_+_109535775 0.39 ENST00000218004.5
nuclear transport factor 2 like export factor 2
chr5_-_157460085 0.39 ENST00000519499.2
Novel protein
chr17_+_7014774 0.39 ENST00000439424.6
chromosome 17 open reading frame 49
chr3_+_184314525 0.39 ENST00000392537.6
ENST00000444134.5
ENST00000450424.5
ENST00000421110.5
ENST00000435046.7
ENST00000382330.7
ENST00000426123.5
ENST00000346169.7
ENST00000350481.9
ENST00000455679.5
ENST00000440448.5
eukaryotic translation initiation factor 4 gamma 1
chr17_+_7015035 0.38 ENST00000552775.1
chromosome 17 open reading frame 49
chr19_-_3500664 0.38 ENST00000427575.6
deoxyhypusine hydroxylase
chrX_+_101408198 0.38 ENST00000316594.6
heterogeneous nuclear ribonucleoprotein H2
chr12_-_93441886 0.37 ENST00000552442.1
ENST00000550657.1
ENST00000318066.7
ubiquitin conjugating enzyme E2 N
chr16_+_67192116 0.37 ENST00000379378.8
E2F transcription factor 4
chr20_-_35284745 0.37 ENST00000374443.7
ENST00000374450.8
eukaryotic translation initiation factor 6
chr2_+_206765578 0.37 ENST00000403094.3
ENST00000402774.8
FAST kinase domains 2
chr2_-_181680490 0.37 ENST00000684145.1
ENST00000295108.4
ENST00000684079.1
ENST00000683430.1
ceramide kinase like
neuronal differentiation 1
chr8_-_27992624 0.36 ENST00000524352.5
scavenger receptor class A member 5
chr3_-_197298558 0.35 ENST00000656944.1
ENST00000346964.6
ENST00000448528.6
ENST00000655488.1
ENST00000357674.9
ENST00000667157.1
ENST00000661336.1
ENST00000654737.1
ENST00000659716.1
ENST00000657381.1
discs large MAGUK scaffold protein 1
chr12_+_100473951 0.35 ENST00000648861.1
ENST00000546380.1
nuclear receptor subfamily 1 group H member 4
chr3_+_184314495 0.35 ENST00000352767.7
ENST00000414031.5
eukaryotic translation initiation factor 4 gamma 1
chr12_-_53336342 0.34 ENST00000537210.2
ENST00000536324.4
Sp7 transcription factor
chr18_-_69947864 0.33 ENST00000582621.6
CD226 molecule
chr7_+_95485934 0.33 ENST00000325885.6
ankyrin repeat and SOCS box containing 4
chr5_+_150661243 0.33 ENST00000517768.6
myozenin 3
chr12_+_123633819 0.33 ENST00000539994.5
ENST00000538845.5
ENST00000228955.11
ENST00000543341.7
ENST00000536375.5
general transcription factor IIH subunit 3
chr12_-_99984227 0.32 ENST00000547776.6
ENST00000547010.5
ankyrin repeat and sterile alpha motif domain containing 1B

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.8 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.6 7.5 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.6 2.8 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.5 8.8 GO:0032329 serine transport(GO:0032329)
0.5 2.0 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.5 2.9 GO:0007296 vitellogenesis(GO:0007296)
0.5 1.9 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.4 1.3 GO:0000103 sulfate assimilation(GO:0000103)
0.4 2.6 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.4 1.7 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.4 1.1 GO:0051941 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.3 1.0 GO:0035498 carnosine metabolic process(GO:0035498)
0.3 4.0 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.3 2.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.3 1.2 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.3 4.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.3 1.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.3 3.7 GO:0019532 oxalate transport(GO:0019532)
0.3 1.8 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.3 0.8 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.2 1.2 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.2 1.4 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.2 0.7 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.2 0.6 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.2 2.6 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2 1.6 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2 0.8 GO:0036269 swimming behavior(GO:0036269)
0.2 1.4 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.2 0.5 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.2 1.0 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.1 0.7 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.1 0.6 GO:0044805 late nucleophagy(GO:0044805)
0.1 0.4 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.1 1.8 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 1.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 0.7 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 2.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 1.5 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 1.1 GO:0048478 replication fork protection(GO:0048478)
0.1 1.8 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 1.7 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 1.3 GO:0034378 chylomicron assembly(GO:0034378)
0.1 0.7 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1 1.6 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.3 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.1 0.4 GO:0034255 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.1 0.6 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.1 0.4 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.6 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.3 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 1.0 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.4 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 0.4 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.5 GO:0008218 bioluminescence(GO:0008218)
0.1 1.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 1.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.8 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 1.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.4 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 5.6 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.3 GO:0010446 response to alkaline pH(GO:0010446)
0.1 0.7 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 2.4 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.1 0.7 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.1 0.4 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 2.2 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.1 0.3 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 0.2 GO:0002215 defense response to nematode(GO:0002215)
0.1 0.5 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 1.5 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.7 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 2.1 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.2 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 1.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.8 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 2.9 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 4.6 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.0 0.5 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.0 0.6 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.9 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.3 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 1.6 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.5 GO:0042407 cristae formation(GO:0042407)
0.0 1.5 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.7 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.5 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 4.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.3 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 1.6 GO:0030317 sperm motility(GO:0030317)
0.0 0.5 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.4 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374) phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 7.0 GO:0006486 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 0.9 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 1.2 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 1.9 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.8 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.2 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.0 0.3 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.7 GO:0050687 negative regulation of defense response to virus(GO:0050687)
0.0 1.6 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.3 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.4 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 3.0 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 1.0 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.3 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.3 GO:0016246 RNA interference(GO:0016246)
0.0 0.4 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.4 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.8 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0045160 myosin I complex(GO:0045160)
0.2 2.6 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.2 6.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.2 1.8 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 2.8 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.2 4.6 GO:0031045 dense core granule(GO:0031045)
0.2 0.7 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.2 0.8 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 1.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.4 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.1 0.7 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 1.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 2.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.5 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 0.7 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.4 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.1 2.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 2.6 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 1.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.7 GO:0001739 sex chromatin(GO:0001739)
0.1 2.2 GO:0030904 retromer complex(GO:0030904)
0.1 0.5 GO:0061617 MICOS complex(GO:0061617)
0.1 0.2 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.1 0.5 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.6 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.2 GO:0031143 pseudopodium(GO:0031143)
0.0 1.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 6.4 GO:0001650 fibrillar center(GO:0001650)
0.0 0.7 GO:0097025 myelin sheath abaxonal region(GO:0035748) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.6 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 2.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 2.1 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.6 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.6 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.5 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 1.2 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 10.0 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 3.0 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.6 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.0 1.4 GO:0015030 Cajal body(GO:0015030)
0.0 3.8 GO:0005882 intermediate filament(GO:0005882)
0.0 1.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.6 GO:0051233 spindle midzone(GO:0051233)
0.0 0.9 GO:0001772 immunological synapse(GO:0001772)
0.0 0.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 1.3 GO:0005771 multivesicular body(GO:0005771)
0.0 10.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.5 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 2.2 GO:0005903 brush border(GO:0005903)
0.0 1.2 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.2 GO:0001520 outer dense fiber(GO:0001520)
0.0 1.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.9 GO:0000922 spindle pole(GO:0000922)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.5 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.7 2.0 GO:0004056 argininosuccinate lyase activity(GO:0004056)
0.6 2.2 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.5 4.6 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.5 1.9 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.4 1.6 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.4 2.5 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.3 1.5 GO:0004905 type I interferon receptor activity(GO:0004905)
0.3 1.2 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.3 5.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.3 3.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.3 0.8 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.2 1.6 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.2 2.4 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.2 1.0 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.2 1.7 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 3.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 1.1 GO:0070728 leucine binding(GO:0070728)
0.1 1.8 GO:0004568 chitinase activity(GO:0004568)
0.1 2.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 1.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 1.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 1.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.4 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.1 1.0 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 1.8 GO:0000150 recombinase activity(GO:0000150)
0.1 1.8 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.1 0.7 GO:0051373 FATZ binding(GO:0051373)
0.1 0.8 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.7 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 0.6 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.9 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.1 1.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.5 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.1 2.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 1.5 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.5 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.1 0.3 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 1.5 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 2.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.3 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 1.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 4.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 0.3 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.9 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.3 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.3 GO:0042835 BRE binding(GO:0042835)
0.0 2.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.5 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.7 GO:0097016 L27 domain binding(GO:0097016)
0.0 1.6 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.4 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.0 1.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.3 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.4 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 1.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.4 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.8 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.6 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.6 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 4.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.9 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.8 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.4 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 3.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.8 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 1.3 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.7 GO:0043394 proteoglycan binding(GO:0043394)
0.0 5.6 GO:0016757 transferase activity, transferring glycosyl groups(GO:0016757)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 1.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 3.3 GO:0004386 helicase activity(GO:0004386)
0.0 1.1 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.5 GO:0004407 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.8 ST GAQ PATHWAY G alpha q Pathway
0.1 1.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 2.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 2.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 2.6 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 3.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 1.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 4.6 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 2.1 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.4 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.8 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.4 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.0 PID ATR PATHWAY ATR signaling pathway
0.0 0.6 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.9 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.7 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.4 PID ATM PATHWAY ATM pathway
0.0 0.8 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 3.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.2 5.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 4.6 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 8.8 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 2.6 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 0.5 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 2.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 1.8 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 2.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.4 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.6 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.7 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 2.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.0 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.8 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.7 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.1 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 1.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.7 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.2 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 2.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1