ISMARA results: HIC1

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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for HIC1

Z-value: 1.13

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Transcription factors associated with HIC1

Gene Symbol	Gene ID	Gene Info
HIC1 Ensembl NCBI GeneCards UniProt	ENSG00000177374.13	HIC1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
HIC1	hg38_v1_chr17_+_2055094_2055110	0.30	1.5e-01	Click!

Activity profile of HIC1 motif

Sorted Z-values of HIC1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HIC1

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Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr3_+_39809602 Show fit	6.63	ENST00000302541.11 ENST00000396217.7	MYRIP Ensembl NCBI GeneCards UniProt Show fit	myosin VIIA and Rab interacting protein
chr1_+_25616780 Show fit	5.76	ENST00000374332.9	MAN1C1 Ensembl NCBI GeneCards UniProt Show fit	mannosidase alpha class 1C member 1
chr9_-_109013483 Show fit	5.55	ENST00000325551.9 ENST00000374593.4 ENST00000374595.8	CTNNAL1 Ensembl NCBI GeneCards UniProt Show fit	catenin alpha like 1
chr4_+_41360759 Show fit	5.28	ENST00000508501.5 ENST00000512946.5 ENST00000313860.11 ENST00000512632.5 ENST00000512820.5	LIMCH1 Ensembl NCBI GeneCards UniProt Show fit	LIM and calponin homology domains 1
chr3_+_32106612 Show fit	4.88	ENST00000282541.10 ENST00000425459.5 ENST00000431009.1	GPD1L Ensembl NCBI GeneCards UniProt Show fit	glycerol-3-phosphate dehydrogenase 1 like
chr2_+_6917404 Show fit	4.23	ENST00000320892.11	RNF144A Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 144A
chr12_+_53046969 Show fit	3.80	ENST00000379902.7	TNS2 Ensembl NCBI GeneCards UniProt Show fit	tensin 2
chr14_-_91060113 Show fit	3.40	ENST00000536315.6	RPS6KA5 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase A5
chr12_+_3077355 Show fit	3.38	ENST00000537971.5 ENST00000011898.10 ENST00000649909.1	TSPAN9 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 9
chr1_+_64745089 Show fit	3.31	ENST00000294428.7 ENST00000371072.8	RAVER2 Ensembl NCBI GeneCards UniProt Show fit	ribonucleoprotein, PTB binding 2
chr20_+_64255728 Show fit	3.24	ENST00000369758.8 ENST00000308824.11 ENST00000609372.1 ENST00000610196.1 ENST00000609764.1	PCMTD2 Ensembl NCBI GeneCards UniProt Show fit	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr1_+_61082398 Show fit	2.90	ENST00000664149.1	NFIA Ensembl NCBI GeneCards UniProt Show fit	nuclear factor I A
chr8_+_27633863 Show fit	2.89	ENST00000337221.8	SCARA3 Ensembl NCBI GeneCards UniProt Show fit	scavenger receptor class A member 3
chr9_+_136712531 Show fit	2.86	ENST00000371692.9	DIPK1B Ensembl NCBI GeneCards UniProt Show fit	divergent protein kinase domain 1B
chr11_-_33869816 Show fit	2.85	ENST00000395833.7	LMO2 Ensembl NCBI GeneCards UniProt Show fit	LIM domain only 2
chr15_+_57376497 Show fit	2.83	ENST00000281282.6	CGNL1 Ensembl NCBI GeneCards UniProt Show fit	cingulin like 1
chr1_+_61082702 Show fit	2.83	ENST00000485903.6 ENST00000371185.6 ENST00000371184.6	NFIA Ensembl NCBI GeneCards UniProt Show fit	nuclear factor I A
chr9_-_75088140 Show fit	2.70	ENST00000361092.9 ENST00000376811.5	NMRK1 Ensembl NCBI GeneCards UniProt Show fit	nicotinamide riboside kinase 1
chr9_-_75088198 Show fit	2.68	ENST00000376808.8	NMRK1 Ensembl NCBI GeneCards UniProt Show fit	nicotinamide riboside kinase 1
chr2_-_156342348 Show fit	2.66	ENST00000409572.5	NR4A2 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 4 group A member 2
chr2_+_241687059 Show fit	2.49	ENST00000636051.1	ING5 Ensembl NCBI GeneCards UniProt Show fit	inhibitor of growth family member 5
chr11_+_95089804 Show fit	2.48	ENST00000278505.5	ENDOD1 Ensembl NCBI GeneCards UniProt Show fit	endonuclease domain containing 1
chr10_+_35127023 Show fit	2.46	ENST00000429130.7 ENST00000469949.6 ENST00000460270.5	CREM Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element modulator
chr12_-_29783798 Show fit	2.32	ENST00000552618.5 ENST00000551659.5 ENST00000539277.6	TMTC1 Ensembl NCBI GeneCards UniProt Show fit	transmembrane O-mannosyltransferase targeting cadherins 1
chr6_+_124962420 Show fit	2.28	ENST00000521654.7 ENST00000560949.5	RNF217 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 217
chr10_+_8054808 Show fit	2.23	ENST00000346208.4	GATA3 Ensembl NCBI GeneCards UniProt Show fit	GATA binding protein 3
chr3_-_64268161 Show fit	2.23	ENST00000564377.6	PRICKLE2 Ensembl NCBI GeneCards UniProt Show fit	prickle planar cell polarity protein 2
chr7_-_11832190 Show fit	2.22	ENST00000423059.9 ENST00000617773.1	THSD7A Ensembl NCBI GeneCards UniProt Show fit	thrombospondin type 1 domain containing 7A
chr3_+_37861926 Show fit	2.18	ENST00000443503.6	CTDSPL Ensembl NCBI GeneCards UniProt Show fit	CTD small phosphatase like
chr22_-_19941798 Show fit	2.17	ENST00000400519.6 ENST00000334363.14 ENST00000400521.7 ENST00000400525.6	TXNRD2 Ensembl NCBI GeneCards UniProt Show fit	thioredoxin reductase 2
chr1_+_61082553 Show fit	2.16	ENST00000403491.8 ENST00000371187.7	NFIA Ensembl NCBI GeneCards UniProt Show fit	nuclear factor I A
chr3_+_52246204 Show fit	2.13	ENST00000409502.7	PPM1M Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase, Mg2+/Mn2+ dependent 1M
chr22_+_23180365 Show fit	2.06	ENST00000359540.7 ENST00000305877.13	BCR Ensembl NCBI GeneCards UniProt Show fit	BCR activator of RhoGEF and GTPase
chr9_+_76459152 Show fit	2.06	ENST00000444201.6 ENST00000376730.5	GCNT1 Ensembl NCBI GeneCards UniProt Show fit	glucosaminyl (N-acetyl) transferase 1
chr12_-_94650506 Show fit	2.06	ENST00000261226.9	TMCC3 Ensembl NCBI GeneCards UniProt Show fit	transmembrane and coiled-coil domain family 3
chr13_+_20703677 Show fit	2.05	ENST00000682841.1	IL17D Ensembl NCBI GeneCards UniProt Show fit	interleukin 17D
chr10_+_8054668 Show fit	2.03	ENST00000379328.9	GATA3 Ensembl NCBI GeneCards UniProt Show fit	GATA binding protein 3
chr3_+_37861849 Show fit	1.98	ENST00000273179.10	CTDSPL Ensembl NCBI GeneCards UniProt Show fit	CTD small phosphatase like
chr4_-_148444674 Show fit	1.98	ENST00000344721.8	NR3C2 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 3 group C member 2
chr13_-_76886397 Show fit	1.97	ENST00000377474.4	KCTD12 Ensembl NCBI GeneCards UniProt Show fit	potassium channel tetramerization domain containing 12
chr18_+_79863668 Show fit	1.94	ENST00000316249.3	KCNG2 Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel modifier subfamily G member 2
chr9_-_13279407 Show fit	1.93	ENST00000546205.5	MPDZ Ensembl NCBI GeneCards UniProt Show fit	multiple PDZ domain crumbs cell polarity complex component
chr1_+_64470120 Show fit	1.86	ENST00000651257.2	CACHD1 Ensembl NCBI GeneCards UniProt Show fit	cache domain containing 1
chr11_-_2139382 Show fit	1.84	ENST00000416167.7	IGF2 Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor 2
chr13_-_106535653 Show fit	1.81	ENST00000646441.1	EFNB2 Ensembl NCBI GeneCards UniProt Show fit	ephrin B2
chr9_-_13279642 Show fit	1.80	ENST00000319217.12	MPDZ Ensembl NCBI GeneCards UniProt Show fit	multiple PDZ domain crumbs cell polarity complex component
chr9_-_13279564 Show fit	1.77	ENST00000541718.5 ENST00000447879.6	MPDZ Ensembl NCBI GeneCards UniProt Show fit	multiple PDZ domain crumbs cell polarity complex component
chr2_-_157876301 Show fit	1.76	ENST00000434821.7	ACVR1 Ensembl NCBI GeneCards UniProt Show fit	activin A receptor type 1
chr8_-_9150648 Show fit	1.73	ENST00000310455.4	PPP1R3B Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory subunit 3B
chr3_+_52245721 Show fit	1.73	ENST00000323588.9	PPM1M Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase, Mg2+/Mn2+ dependent 1M
chr14_-_38256074 Show fit	1.73	ENST00000342213.3	CLEC14A Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain containing 14A
chr17_+_63477052 Show fit	1.71	ENST00000290866.10 ENST00000428043.5	ACE Ensembl NCBI GeneCards UniProt Show fit	angiotensin I converting enzyme
chr7_-_87059639 Show fit	1.71	ENST00000450689.7	ELAPOR2 Ensembl NCBI GeneCards UniProt Show fit	endosome-lysosome associated apoptosis and autophagy regulator family member 2
chr8_+_27633884 Show fit	1.68	ENST00000301904.4	SCARA3 Ensembl NCBI GeneCards UniProt Show fit	scavenger receptor class A member 3
chr7_-_87059515 Show fit	1.68	ENST00000423294.5	ELAPOR2 Ensembl NCBI GeneCards UniProt Show fit	endosome-lysosome associated apoptosis and autophagy regulator family member 2
chr5_+_122312229 Show fit	1.66	ENST00000261368.13	SNCAIP Ensembl NCBI GeneCards UniProt Show fit	synuclein alpha interacting protein
chr7_+_107044689 Show fit	1.65	ENST00000265717.5	PRKAR2B Ensembl NCBI GeneCards UniProt Show fit	protein kinase cAMP-dependent type II regulatory subunit beta
chr13_-_48533165 Show fit	1.65	ENST00000430805.6 ENST00000544492.5 ENST00000544904.3	RCBTB2 Ensembl NCBI GeneCards UniProt Show fit	RCC1 and BTB domain containing protein 2
chr20_+_11890785 Show fit	1.64	ENST00000399006.6 ENST00000405977.5	BTBD3 Ensembl NCBI GeneCards UniProt Show fit	BTB domain containing 3
chr12_-_42589737 Show fit	1.61	ENST00000345127.9 ENST00000639958.1	PRICKLE1 Ensembl NCBI GeneCards UniProt Show fit	prickle planar cell polarity protein 1
chr3_+_20040437 Show fit	1.61	ENST00000263754.5	KAT2B Ensembl NCBI GeneCards UniProt Show fit	lysine acetyltransferase 2B
chr1_+_84078043 Show fit	1.58	ENST00000370689.6 ENST00000370688.7	PRKACB Ensembl NCBI GeneCards UniProt Show fit	protein kinase cAMP-activated catalytic subunit beta
chr2_+_12716893 Show fit	1.57	ENST00000381465.2 ENST00000155926.9	TRIB2 Ensembl NCBI GeneCards UniProt Show fit	tribbles pseudokinase 2
chr19_-_4581755 Show fit	1.57	ENST00000676793.1	SEMA6B Ensembl NCBI GeneCards UniProt Show fit	semaphorin 6B
chr17_+_67825494 Show fit	1.56	ENST00000306378.11 ENST00000544778.6	BPTF Ensembl NCBI GeneCards UniProt Show fit	bromodomain PHD finger transcription factor
chr7_-_87059624 Show fit	1.54	ENST00000444627.5	ELAPOR2 Ensembl NCBI GeneCards UniProt Show fit	endosome-lysosome associated apoptosis and autophagy regulator family member 2
chr3_+_52246158 Show fit	1.54	ENST00000296487.8	PPM1M Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase, Mg2+/Mn2+ dependent 1M
chr10_+_35126791 Show fit	1.53	ENST00000474362.5 ENST00000374721.7	CREM Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element modulator
chr9_-_10612966 Show fit	1.53	ENST00000381196.9	PTPRD Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase receptor type D
chr13_-_48533069 Show fit	1.52	ENST00000344532.8	RCBTB2 Ensembl NCBI GeneCards UniProt Show fit	RCC1 and BTB domain containing protein 2
chr10_+_35127162 Show fit	1.51	ENST00000354759.7	CREM Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element modulator
chr9_-_122228845 Show fit	1.50	ENST00000394319.8 ENST00000340587.7	LHX6 Ensembl NCBI GeneCards UniProt Show fit	LIM homeobox 6
chr10_-_124744280 Show fit	1.50	ENST00000337318.8	FAM53B Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 53 member B
chr4_-_98658582 Show fit	1.50	ENST00000305798.8	TSPAN5 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 5
chr6_-_83709382 Show fit	1.49	ENST00000520302.5 ENST00000520213.5 ENST00000439399.6	SNAP91 Ensembl NCBI GeneCards UniProt Show fit	synaptosome associated protein 91
chr12_+_93571664 Show fit	1.47	ENST00000622746.4 ENST00000548537.1	SOCS2 Ensembl NCBI GeneCards UniProt Show fit	suppressor of cytokine signaling 2
chr10_+_115093404 Show fit	1.47	ENST00000527407.5	ATRNL1 Ensembl NCBI GeneCards UniProt Show fit	attractin like 1
chr7_-_28958321 Show fit	1.46	ENST00000539664.3	TRIL Ensembl NCBI GeneCards UniProt Show fit	TLR4 interactor with leucine rich repeats
chr12_+_52948840 Show fit	1.46	ENST00000388837.6 ENST00000550600.5	KRT18 Ensembl NCBI GeneCards UniProt Show fit	keratin 18
chr8_-_28386073 Show fit	1.45	ENST00000523095.5 ENST00000522795.1	ZNF395 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 395
chr11_-_47186399 Show fit	1.45	ENST00000531226.5 ENST00000524509.1 ENST00000298838.11 ENST00000528201.1 ENST00000530513.5	PACSIN3 Ensembl NCBI GeneCards UniProt Show fit	protein kinase C and casein kinase substrate in neurons 3
chr6_-_83709141 Show fit	1.43	ENST00000521743.5	SNAP91 Ensembl NCBI GeneCards UniProt Show fit	synaptosome associated protein 91
chr6_+_107490103 Show fit	1.43	ENST00000317357.10	SOBP Ensembl NCBI GeneCards UniProt Show fit	sine oculis binding protein homolog
chr19_-_3029013 Show fit	1.43	ENST00000590536.5 ENST00000587137.5 ENST00000455444.6	TLE2 Ensembl NCBI GeneCards UniProt Show fit	TLE family member 2, transcriptional corepressor
chr6_-_83709019 Show fit	1.42	ENST00000519779.5 ENST00000369694.6 ENST00000195649.10	SNAP91 Ensembl NCBI GeneCards UniProt Show fit	synaptosome associated protein 91
chr14_+_63852951 Show fit	1.41	ENST00000357395.7 ENST00000358025.7 ENST00000344113.8 ENST00000341472.9 ENST00000555002.6	SYNE2 Ensembl NCBI GeneCards UniProt Show fit	spectrin repeat containing nuclear envelope protein 2
chr12_+_96194501 Show fit	1.40	ENST00000552142.5	ELK3 Ensembl NCBI GeneCards UniProt Show fit	ETS transcription factor ELK3
chr2_+_70258088 Show fit	1.39	ENST00000433351.7 ENST00000264441.9	PCYOX1 Ensembl NCBI GeneCards UniProt Show fit	prenylcysteine oxidase 1
chr4_-_25862979 Show fit	1.38	ENST00000399878.8	SEL1L3 Ensembl NCBI GeneCards UniProt Show fit	SEL1L family member 3
chr20_+_43945677 Show fit	1.38	ENST00000358131.5	TOX2 Ensembl NCBI GeneCards UniProt Show fit	TOX high mobility group box family member 2
chr20_+_36092698 Show fit	1.37	ENST00000430276.5 ENST00000373950.6 ENST00000373946.7 ENST00000441639.5 ENST00000628415.2 ENST00000452261.5	EPB41L1 Ensembl NCBI GeneCards UniProt Show fit	erythrocyte membrane protein band 4.1 like 1
chr11_+_33376077 Show fit	1.37	ENST00000658780.2	KIAA1549L Ensembl NCBI GeneCards UniProt Show fit	KIAA1549 like
chr9_-_16870662 Show fit	1.36	ENST00000380672.9	BNC2 Ensembl NCBI GeneCards UniProt Show fit	basonuclin 2
chr9_+_137077467 Show fit	1.36	ENST00000409858.8	UAP1L1 Ensembl NCBI GeneCards UniProt Show fit	UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
chr9_-_16870702 Show fit	1.35	ENST00000380667.6 ENST00000545497.5 ENST00000486514.5	BNC2 Ensembl NCBI GeneCards UniProt Show fit	basonuclin 2
chr3_-_9553796 Show fit	1.35	ENST00000287585.8	LHFPL4 Ensembl NCBI GeneCards UniProt Show fit	LHFPL tetraspan subfamily member 4
chrX_+_150363306 Show fit	1.34	ENST00000370401.7 ENST00000432680.7	MAMLD1 Ensembl NCBI GeneCards UniProt Show fit	mastermind like domain containing 1
chr12_+_93571832 Show fit	1.33	ENST00000549887.1	SOCS2 Ensembl NCBI GeneCards UniProt Show fit	suppressor of cytokine signaling 2
chrX_+_150363258 Show fit	1.32	ENST00000683696.1	MAMLD1 Ensembl NCBI GeneCards UniProt Show fit	mastermind like domain containing 1
chr2_+_176188658 Show fit	1.32	ENST00000331462.6	HOXD1 Ensembl NCBI GeneCards UniProt Show fit	homeobox D1
chr14_+_65412949 Show fit	1.31	ENST00000674118.1 ENST00000553924.5 ENST00000358307.6 ENST00000557338.5 ENST00000554610.1	FUT8 Ensembl NCBI GeneCards UniProt Show fit	fucosyltransferase 8
chr6_-_42048648 Show fit	1.30	ENST00000502771.1 ENST00000508143.5 ENST00000514588.1 ENST00000510503.5	CCND3 Ensembl NCBI GeneCards UniProt Show fit	cyclin D3
chr22_+_19714450 Show fit	1.28	ENST00000455784.7 ENST00000406395.5	SEPTIN5 Ensembl NCBI GeneCards UniProt Show fit	septin 5
chr3_+_48990219 Show fit	1.28	ENST00000383729.9	P4HTM Ensembl NCBI GeneCards UniProt Show fit	prolyl 4-hydroxylase, transmembrane
chr17_+_67825664 Show fit	1.27	ENST00000321892.8	BPTF Ensembl NCBI GeneCards UniProt Show fit	bromodomain PHD finger transcription factor
chr14_-_91060578 Show fit	1.26	ENST00000418736.6 ENST00000614987.5	RPS6KA5 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase A5
chr3_+_32238667 Show fit	1.22	ENST00000458535.6 ENST00000307526.4	CMTM8 Ensembl NCBI GeneCards UniProt Show fit	CKLF like MARVEL transmembrane domain containing 8
chrX_+_10015226 Show fit	1.22	ENST00000380861.9	WWC3 Ensembl NCBI GeneCards UniProt Show fit	WWC family member 3
chr19_-_3029269 Show fit	1.21	ENST00000262953.11	TLE2 Ensembl NCBI GeneCards UniProt Show fit	TLE family member 2, transcriptional corepressor
chr6_+_18387326 Show fit	1.20	ENST00000259939.4	RNF144B Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 144B
chr11_-_66347560 Show fit	1.20	ENST00000311181.5	B4GAT1 Ensembl NCBI GeneCards UniProt Show fit	beta-1,4-glucuronyltransferase 1
chr8_+_6708626 Show fit	1.19	ENST00000285518.11	AGPAT5 Ensembl NCBI GeneCards UniProt Show fit	1-acylglycerol-3-phosphate O-acyltransferase 5
chr2_-_98731063 Show fit	1.19	ENST00000393487.6	MGAT4A Ensembl NCBI GeneCards UniProt Show fit	alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
chr3_+_50155305 Show fit	1.18	ENST00000002829.8 ENST00000426511.5	SEMA3F Ensembl NCBI GeneCards UniProt Show fit	semaphorin 3F
chr14_-_100306430 Show fit	1.17	ENST00000392908.7 ENST00000359232.8	SLC25A29 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 25 member 29
chr11_+_119149029 Show fit	1.17	ENST00000619701.5	ABCG4 Ensembl NCBI GeneCards UniProt Show fit	ATP binding cassette subfamily G member 4
chr11_-_68121370 Show fit	1.17	ENST00000265689.9 ENST00000356135.9	CHKA Ensembl NCBI GeneCards UniProt Show fit	choline kinase alpha
chr6_-_56954747 Show fit	1.16	ENST00000680361.1	DST Ensembl NCBI GeneCards UniProt Show fit	dystonin
chr5_+_95731300 Show fit	1.16	ENST00000379982.8	RHOBTB3 Ensembl NCBI GeneCards UniProt Show fit	Rho related BTB domain containing 3
chr4_-_25863537 Show fit	1.16	ENST00000502949.5 ENST00000264868.9 ENST00000513691.1 ENST00000514872.1	SEL1L3 Ensembl NCBI GeneCards UniProt Show fit	SEL1L family member 3
chr11_+_111977300 Show fit	1.15	ENST00000615255.1	DIXDC1 Ensembl NCBI GeneCards UniProt Show fit	DIX domain containing 1
chr6_+_16129077 Show fit	1.15	ENST00000356840.8 ENST00000349606.4	MYLIP Ensembl NCBI GeneCards UniProt Show fit	myosin regulatory light chain interacting protein
chr6_+_7726089 Show fit	1.15	ENST00000283147.7	BMP6 Ensembl NCBI GeneCards UniProt Show fit	bone morphogenetic protein 6
chr10_+_35127295 Show fit	1.14	ENST00000489321.5 ENST00000427847.6 ENST00000374728.7 ENST00000345491.7 ENST00000487132.5	CREM Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element modulator
chr1_+_32539418 Show fit	1.14	ENST00000373510.9 ENST00000316459.4	ZBTB8A Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 8A
chr19_-_13102848 Show fit	1.13	ENST00000264824.5	LYL1 Ensembl NCBI GeneCards UniProt Show fit	LYL1 basic helix-loop-helix family member
chr19_+_51693327 Show fit	1.13	ENST00000637797.2	SPACA6 Ensembl NCBI GeneCards UniProt Show fit	sperm acrosome associated 6
chr9_+_36036899 Show fit	1.13	ENST00000377966.4	RECK Ensembl NCBI GeneCards UniProt Show fit	reversion inducing cysteine rich protein with kazal motifs
chr12_-_95790755 Show fit	1.12	ENST00000343702.9 ENST00000344911.8	NTN4 Ensembl NCBI GeneCards UniProt Show fit	netrin 4
chr9_+_68705230 Show fit	1.12	ENST00000265382.8	PIP5K1B Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol-4-phosphate 5-kinase type 1 beta
chr11_+_65111845 Show fit	1.11	ENST00000526809.5 ENST00000524986.5 ENST00000534371.5 ENST00000279263.14 ENST00000525385.5 ENST00000345348.9 ENST00000531321.5 ENST00000529414.5 ENST00000526085.5 ENST00000530750.5	TM7SF2 Ensembl NCBI GeneCards UniProt Show fit	transmembrane 7 superfamily member 2
chr9_+_127612222 Show fit	1.11	ENST00000637953.1 ENST00000636962.2	STXBP1 Ensembl NCBI GeneCards UniProt Show fit	syntaxin binding protein 1
chr13_+_26557659 Show fit	1.11	ENST00000335327.6 ENST00000361042.8 ENST00000671038.1	WASF3 Ensembl NCBI GeneCards UniProt Show fit	WASP family member 3
chr1_-_236065079 Show fit	1.11	ENST00000264187.7 ENST00000366595.7	NID1 Ensembl NCBI GeneCards UniProt Show fit	nidogen 1
chrX_+_46573757 Show fit	1.11	ENST00000276055.4	CHST7 Ensembl NCBI GeneCards UniProt Show fit	carbohydrate sulfotransferase 7
chr3_+_50155024 Show fit	1.10	ENST00000414301.5 ENST00000450338.5 ENST00000413852.5	SEMA3F Ensembl NCBI GeneCards UniProt Show fit	semaphorin 3F
chr9_+_131096476 Show fit	1.09	ENST00000372309.7 ENST00000247291.8 ENST00000372302.5 ENST00000372300.5 ENST00000372298.1	AIF1L Ensembl NCBI GeneCards UniProt Show fit	allograft inflammatory factor 1 like
chr13_-_36920227 Show fit	1.09	ENST00000379826.5 ENST00000350148.10	SMAD9 Ensembl NCBI GeneCards UniProt Show fit	SMAD family member 9
chr9_+_126326809 Show fit	1.09	ENST00000361171.8 ENST00000489637.3	MVB12B Ensembl NCBI GeneCards UniProt Show fit	multivesicular body subunit 12B
chr11_-_64803152 Show fit	1.09	ENST00000439069.5 ENST00000294066.7 ENST00000377350.7	MAP4K2 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase kinase 2
chr19_-_14206168 Show fit	1.09	ENST00000361434.7 ENST00000340736.10	ADGRL1 Ensembl NCBI GeneCards UniProt Show fit	adhesion G protein-coupled receptor L1
chr1_+_32741779 Show fit	1.08	ENST00000401073.7	KIAA1522 Ensembl NCBI GeneCards UniProt Show fit	KIAA1522
chr17_+_6071075 Show fit	1.08	ENST00000574232.5 ENST00000539421.1	WSCD1 Ensembl NCBI GeneCards UniProt Show fit	WSC domain containing 1
chr18_-_75209126 Show fit	1.07	ENST00000322342.4	ZADH2 Ensembl NCBI GeneCards UniProt Show fit	zinc binding alcohol dehydrogenase domain containing 2
chr3_+_48989876 Show fit	1.06	ENST00000343546.8	P4HTM Ensembl NCBI GeneCards UniProt Show fit	prolyl 4-hydroxylase, transmembrane
chr12_-_123271089 Show fit	1.06	ENST00000535979.5	CDK2AP1 Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase 2 associated protein 1
chr22_-_26590082 Show fit	1.05	ENST00000442495.5 ENST00000440953.5 ENST00000450022.1 ENST00000338754.9	TPST2 Ensembl NCBI GeneCards UniProt Show fit	tyrosylprotein sulfotransferase 2
chr5_+_69415065 Show fit	1.05	ENST00000647531.1 ENST00000645446.1 ENST00000325631.10 ENST00000454295.6	MARVELD2 Ensembl NCBI GeneCards UniProt Show fit	MARVEL domain containing 2
chr2_-_75560893 Show fit	1.03	ENST00000410113.5 ENST00000393913.8	EVA1A Ensembl NCBI GeneCards UniProt Show fit	eva-1 homolog A, regulator of programmed cell death
chr17_+_83079595 Show fit	1.03	ENST00000320095.12	METRNL Ensembl NCBI GeneCards UniProt Show fit	meteorin like, glial cell differentiation regulator
chr22_+_19941813 Show fit	1.02	ENST00000678769.1	COMT Ensembl NCBI GeneCards UniProt Show fit	catechol-O-methyltransferase
chr1_+_14924100 Show fit	1.02	ENST00000361144.9	KAZN Ensembl NCBI GeneCards UniProt Show fit	kazrin, periplakin interacting protein
chr8_-_102655707 Show fit	1.02	ENST00000285407.11	KLF10 Ensembl NCBI GeneCards UniProt Show fit	Kruppel like factor 10
chr12_-_42589592 Show fit	1.01	ENST00000552108.6 ENST00000547113.1 ENST00000640646.1	PRICKLE1 Ensembl NCBI GeneCards UniProt Show fit	prickle planar cell polarity protein 1
chr8_-_88327475 Show fit	1.00	ENST00000286614.11	MMP16 Ensembl NCBI GeneCards UniProt Show fit	matrix metallopeptidase 16
chr9_+_67859398 Show fit	1.00	ENST00000620792.1	ANKRD20A1 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat domain 20 family member A1
chr9_+_68705414 Show fit	1.00	ENST00000541509.5	PIP5K1B Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol-4-phosphate 5-kinase type 1 beta
chr13_-_45418337 Show fit	0.99	ENST00000519676.6 ENST00000519547.5	SLC25A30 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 25 member 30
chr9_+_69325168 Show fit	0.99	ENST00000303068.14	FAM189A2 Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 189 member A2
chr3_+_43286512 Show fit	0.99	ENST00000454177.5 ENST00000429705.6 ENST00000296088.12 ENST00000437827.1	SNRK Ensembl NCBI GeneCards UniProt Show fit	SNF related kinase
chr14_+_96039328 Show fit	0.99	ENST00000553764.1 ENST00000555004.3 ENST00000556728.1 ENST00000553782.1	C14orf132 Ensembl NCBI GeneCards UniProt Show fit	chromosome 14 open reading frame 132
chr18_+_9334757 Show fit	0.99	ENST00000262120.10 ENST00000581641.1	TWSG1 Ensembl NCBI GeneCards UniProt Show fit	twisted gastrulation BMP signaling modulator 1
chr7_-_149773548 Show fit	0.99	ENST00000302017.4	ZNF467 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 467
chr3_-_124887353 Show fit	0.98	ENST00000296181.9	ITGB5 Ensembl NCBI GeneCards UniProt Show fit	integrin subunit beta 5
chr2_+_46297397 Show fit	0.98	ENST00000263734.5	EPAS1 Ensembl NCBI GeneCards UniProt Show fit	endothelial PAS domain protein 1
chr1_-_97920986 Show fit	0.98	ENST00000370192.8	DPYD Ensembl NCBI GeneCards UniProt Show fit	dihydropyrimidine dehydrogenase
chr17_+_6070361 Show fit	0.97	ENST00000317744.10	WSCD1 Ensembl NCBI GeneCards UniProt Show fit	WSC domain containing 1
chr10_+_92848461 Show fit	0.97	ENST00000443748.6 ENST00000371543.5 ENST00000260762.10	EXOC6 Ensembl NCBI GeneCards UniProt Show fit	exocyst complex component 6
chr10_+_35336486 Show fit	0.97	ENST00000374704.8	CCNY Ensembl NCBI GeneCards UniProt Show fit	cyclin Y
chr21_+_46286623 Show fit	0.95	ENST00000397691.1	YBEY Ensembl NCBI GeneCards UniProt Show fit	ybeY metalloendoribonuclease
chr16_+_81444799 Show fit	0.95	ENST00000537098.8	CMIP Ensembl NCBI GeneCards UniProt Show fit	c-Maf inducing protein
chr22_+_19723525 Show fit	0.95	ENST00000366425.4	GP1BB Ensembl NCBI GeneCards UniProt Show fit	glycoprotein Ib platelet subunit beta
chr15_-_34583592 Show fit	0.94	ENST00000683415.1	GOLGA8B Ensembl NCBI GeneCards UniProt Show fit	golgin A8 family member B
chr14_+_92513766 Show fit	0.94	ENST00000216487.12 ENST00000620541.4 ENST00000557762.1	RIN3 Ensembl NCBI GeneCards UniProt Show fit	Ras and Rab interactor 3
chr2_-_69643615 Show fit	0.94	ENST00000409068.5	AAK1 Ensembl NCBI GeneCards UniProt Show fit	AP2 associated kinase 1
chr19_-_41353904 Show fit	0.94	ENST00000221930.6	TGFB1 Ensembl NCBI GeneCards UniProt Show fit	transforming growth factor beta 1
chr21_-_38660656 Show fit	0.94	ENST00000398919.6	ERG Ensembl NCBI GeneCards UniProt Show fit	ETS transcription factor ERG
chr11_-_119340544 Show fit	0.94	ENST00000530681.2	C1QTNF5 Ensembl NCBI GeneCards UniProt Show fit	C1q and TNF related 5
chr4_-_113761724 Show fit	0.93	ENST00000511664.6	CAMK2D Ensembl NCBI GeneCards UniProt Show fit	calcium/calmodulin dependent protein kinase II delta
chr2_-_164621461 Show fit	0.93	ENST00000446413.6 ENST00000263915.8	GRB14 Ensembl NCBI GeneCards UniProt Show fit	growth factor receptor bound protein 14
chr6_+_117482634 Show fit	0.93	ENST00000296955.12 ENST00000338728.10	DCBLD1 Ensembl NCBI GeneCards UniProt Show fit	discoidin, CUB and LCCL domain containing 1
chr9_+_127612257 Show fit	0.93	ENST00000637173.2 ENST00000630492.2 ENST00000627871.2 ENST00000373302.8 ENST00000373299.5 ENST00000650920.1 ENST00000476182.3	STXBP1 Ensembl NCBI GeneCards UniProt Show fit	syntaxin binding protein 1
chr22_-_29581074 Show fit	0.93	ENST00000415100.5 ENST00000216121.12	NIPSNAP1 Ensembl NCBI GeneCards UniProt Show fit	nipsnap homolog 1
chr22_+_19941733 Show fit	0.92	ENST00000403184.5 ENST00000361682.11 ENST00000403710.5 ENST00000407537.5 ENST00000678868.1	COMT Ensembl NCBI GeneCards UniProt Show fit	catechol-O-methyltransferase
chr5_+_122312164 Show fit	0.92	ENST00000514497.6 ENST00000261367.11	SNCAIP Ensembl NCBI GeneCards UniProt Show fit	synuclein alpha interacting protein
chr11_+_925840 Show fit	0.92	ENST00000448903.7 ENST00000525796.5 ENST00000534328.5	AP2A2 Ensembl NCBI GeneCards UniProt Show fit	adaptor related protein complex 2 subunit alpha 2
chr7_-_149773207 Show fit	0.92	ENST00000484747.5	ZNF467 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 467
chr13_-_100674813 Show fit	0.91	ENST00000376234.7 ENST00000423847.1	TMTC4 Ensembl NCBI GeneCards UniProt Show fit	transmembrane O-mannosyltransferase targeting cadherins 4
chr9_-_78031775 Show fit	0.91	ENST00000286548.9	GNAQ Ensembl NCBI GeneCards UniProt Show fit	G protein subunit alpha q
chr8_-_73746830 Show fit	0.91	ENST00000524300.6 ENST00000523558.5 ENST00000521210.5 ENST00000355780.9 ENST00000524104.5 ENST00000521736.5 ENST00000521447.5 ENST00000517542.5 ENST00000521451.5 ENST00000521419.5 ENST00000518502.5	STAU2 Ensembl NCBI GeneCards UniProt Show fit	staufen double-stranded RNA binding protein 2
chr5_+_122311740 Show fit	0.91	ENST00000506272.5 ENST00000508681.5 ENST00000509154.6	SNCAIP Ensembl NCBI GeneCards UniProt Show fit	synuclein alpha interacting protein
chr2_-_69643152 Show fit	0.91	ENST00000606389.7	AAK1 Ensembl NCBI GeneCards UniProt Show fit	AP2 associated kinase 1
chr17_+_30970984 Show fit	0.91	ENST00000443677.6 ENST00000324689.8 ENST00000328381.10 ENST00000535306.6 ENST00000580444.2	RNF135 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 135
chr1_-_109397888 Show fit	0.90	ENST00000256637.8	SORT1 Ensembl NCBI GeneCards UniProt Show fit	sortilin 1
chr10_-_125158704 Show fit	0.90	ENST00000531469.5	CTBP2 Ensembl NCBI GeneCards UniProt Show fit	C-terminal binding protein 2
chr17_-_50866347 Show fit	0.90	ENST00000499247.3	TOB1 Ensembl NCBI GeneCards UniProt Show fit	transducer of ERBB2, 1
chr2_+_241558716 Show fit	0.89	ENST00000318407.5	BOK Ensembl NCBI GeneCards UniProt Show fit	BCL2 family apoptosis regulator BOK
chr7_-_120857124 Show fit	0.89	ENST00000441017.5 ENST00000424710.5 ENST00000433758.5	TSPAN12 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 12
chr12_+_131894615 Show fit	0.89	ENST00000321867.6	ULK1 Ensembl NCBI GeneCards UniProt Show fit	unc-51 like autophagy activating kinase 1
chr16_-_4614876 Show fit	0.88	ENST00000591401.5 ENST00000283474.12 ENST00000591897.5	UBALD1 Ensembl NCBI GeneCards UniProt Show fit	UBA like domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	4.9	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
1.5	4.6	GO:0072204	cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
1.4	5.8	GO:1904381	Golgi apparatus mannose trimming(GO:1904381)
0.9	4.7	GO:0043988	histone H3-S28 phosphorylation(GO:0043988)
0.9	2.7	GO:0021986	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.9	0.9	GO:0061441	renal artery morphogenesis(GO:0061441)
0.6	1.8	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.6	1.8	GO:0061445	endocardial cell fate commitment(GO:0060957) endocardial cushion cell fate commitment(GO:0061445)
0.5	2.6	GO:2000691	negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.5	2.1	GO:0043314	negative regulation of neutrophil degranulation(GO:0043314) negative regulation of respiratory burst(GO:0060268)
0.5	2.0	GO:1903296	regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296)
0.5	1.5	GO:0043000	Golgi to plasma membrane CFTR protein transport(GO:0043000)
0.5	6.7	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.5	3.2	GO:0097338	response to clozapine(GO:0097338)
0.4	2.7	GO:0050668	cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.4	1.3	GO:1990535	neuron projection maintenance(GO:1990535)
0.4	1.3	GO:0036071	N-glycan fucosylation(GO:0036071)
0.4	1.2	GO:1904772	hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.4	1.6	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.4	1.2	GO:1902024	histidine transport(GO:0015817) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.4	1.1	GO:0090031	positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.4	1.9	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.4	1.1	GO:0071344	diphosphate metabolic process(GO:0071344)
0.4	1.1	GO:0006478	peptidyl-tyrosine sulfation(GO:0006478)
0.3	1.7	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.3	1.0	GO:0042412	taurine biosynthetic process(GO:0042412)
0.3	1.0	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.3	1.0	GO:1902462	regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.3	2.3	GO:0035290	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.3	1.2	GO:0044210	'de novo' CTP biosynthetic process(GO:0044210)
0.3	0.9	GO:0019483	uracil catabolic process(GO:0006212) beta-alanine biosynthetic process(GO:0019483)
0.3	0.9	GO:0072720	response to dithiothreitol(GO:0072720)
0.3	1.1	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.3	1.1	GO:0048627	myoblast development(GO:0048627)
0.3	1.6	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.3	1.5	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.3	7.7	GO:0072189	ureter development(GO:0072189)
0.2	0.7	GO:0031064	negative regulation of histone deacetylation(GO:0031064)
0.2	0.7	GO:2001153	regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.2	1.0	GO:0044313	protein K6-linked deubiquitination(GO:0044313)
0.2	1.8	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.2	1.2	GO:0032484	Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.2	0.7	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.2	0.7	GO:1902683	regulation of receptor localization to synapse(GO:1902683)
0.2	0.9	GO:0009405	pathogenesis(GO:0009405)
0.2	1.1	GO:0019075	virus maturation(GO:0019075)
0.2	1.1	GO:2001295	malonyl-CoA biosynthetic process(GO:2001295)
0.2	0.8	GO:0002270	plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711)
0.2	2.9	GO:0021853	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.2	0.8	GO:0046379	extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.2	0.6	GO:0002316	follicular B cell differentiation(GO:0002316)
0.2	0.6	GO:0003192	mitral valve formation(GO:0003192)
0.2	0.6	GO:0097187	dentinogenesis(GO:0097187)
0.2	1.5	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.2	0.8	GO:0015772	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.2	1.1	GO:0030311	poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.2	1.7	GO:0060179	male mating behavior(GO:0060179)
0.2	1.3	GO:0075071	autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.2	1.1	GO:0033088	immature T cell proliferation in thymus(GO:0033080) regulation of immature T cell proliferation in thymus(GO:0033084) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.2	0.7	GO:1901382	chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.2	2.2	GO:0001955	blood vessel maturation(GO:0001955)
0.2	1.1	GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.2	1.4	GO:0099515	nuclear migration along microfilament(GO:0031022) actin filament-based transport(GO:0099515)
0.2	0.7	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
0.2	2.1	GO:0060352	cell adhesion molecule production(GO:0060352)
0.2	0.5	GO:0043396	corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.2	0.7	GO:0009956	radial pattern formation(GO:0009956)
0.2	0.8	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.2	0.2	GO:0006447	regulation of translational initiation by iron(GO:0006447)
0.2	0.8	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.2	1.3	GO:0002329	pre-B cell differentiation(GO:0002329)
0.2	0.6	GO:0021965	spinal cord ventral commissure morphogenesis(GO:0021965)
0.2	1.6	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.2	0.5	GO:0048073	regulation of eye pigmentation(GO:0048073)
0.2	5.5	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.2	0.8	GO:0060160	negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.2	1.4	GO:0032803	regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803)
0.2	0.3	GO:0070318	positive regulation of G0 to G1 transition(GO:0070318)
0.2	0.6	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.2	0.6	GO:0002384	hepatic immune response(GO:0002384)
0.2	3.9	GO:0009650	UV protection(GO:0009650)
0.2	0.6	GO:0032474	otolith morphogenesis(GO:0032474)
0.2	0.5	GO:0002086	diaphragm contraction(GO:0002086)
0.1	0.9	GO:0033490	cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1	1.3	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.1	1.3	GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1	1.9	GO:0072307	metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1	0.9	GO:0006574	valine catabolic process(GO:0006574)
0.1	1.1	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.1	1.5	GO:0072178	nephric duct morphogenesis(GO:0072178)
0.1	1.5	GO:0006657	CDP-choline pathway(GO:0006657)
0.1	4.7	GO:0014850	response to muscle activity(GO:0014850)
0.1	1.0	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.1	0.4	GO:0021593	rhombomere morphogenesis(GO:0021593) rhombomere 3 morphogenesis(GO:0021658)
0.1	3.0	GO:0042789	mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1	0.4	GO:0060931	sinoatrial node cell development(GO:0060931)
0.1	1.7	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1	0.8	GO:0016129	ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204) phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129)
0.1	0.5	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.1	0.5	GO:0001927	exocyst assembly(GO:0001927)
0.1	5.2	GO:0009435	NAD biosynthetic process(GO:0009435)
0.1	0.9	GO:0032377	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1	0.9	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1	0.7	GO:0008218	bioluminescence(GO:0008218)
0.1	1.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.1	0.4	GO:0021718	pons maturation(GO:0021586) superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1	1.6	GO:0098909	regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1	0.3	GO:0018002	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1	0.9	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1	0.3	GO:0036363	transforming growth factor beta activation(GO:0036363) regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
0.1	7.0	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.1	0.3	GO:1902512	positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.1	1.0	GO:0032482	Rab protein signal transduction(GO:0032482)
0.1	0.4	GO:0036518	chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.1	0.3	GO:0022018	subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875)
0.1	2.8	GO:0003416	endochondral bone growth(GO:0003416)
0.1	2.4	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.1	1.3	GO:0043129	surfactant homeostasis(GO:0043129)
0.1	0.4	GO:0097089	methyl-branched fatty acid metabolic process(GO:0097089)
0.1	0.7	GO:1905123	regulation of glucosylceramidase activity(GO:1905123)
0.1	3.7	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.1	0.7	GO:0015798	myo-inositol transport(GO:0015798)
0.1	0.2	GO:0034427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.1	0.4	GO:0010430	fatty acid omega-oxidation(GO:0010430)
0.1	0.3	GO:1903028	asymmetric Golgi ribbon formation(GO:0090164) positive regulation of opsonization(GO:1903028)
0.1	0.8	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) lung vasculature development(GO:0060426)
0.1	0.6	GO:0034499	late endosome to Golgi transport(GO:0034499)
0.1	0.3	GO:0061580	colon epithelial cell migration(GO:0061580)
0.1	0.4	GO:0030200	heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1	1.9	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1	1.2	GO:0090168	Golgi reassembly(GO:0090168)
0.1	1.5	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.1	1.4	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.1	0.5	GO:1901907	diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1	0.5	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1	0.5	GO:0032487	regulation of Rap protein signal transduction(GO:0032487)
0.1	0.3	GO:0061011	negative regulation of transcription by transcription factor localization(GO:0010621) hepatic duct development(GO:0061011) hepatoblast differentiation(GO:0061017)
0.1	0.4	GO:0007386	compartment pattern specification(GO:0007386)
0.1	0.3	GO:0000710	meiotic mismatch repair(GO:0000710)
0.1	0.4	GO:1901350	cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.1	1.2	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.1	0.2	GO:0051228	mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.1	1.0	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.1	1.4	GO:0006450	regulation of translational fidelity(GO:0006450)
0.1	1.5	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.1	0.5	GO:0090116	C-5 methylation of cytosine(GO:0090116)
0.1	0.2	GO:0035494	SNARE complex disassembly(GO:0035494)
0.1	0.5	GO:0033274	response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1	0.6	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.1	0.2	GO:0031508	pericentric heterochromatin assembly(GO:0031508)
0.1	0.6	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1	0.2	GO:0003064	regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.1	0.3	GO:1903288	positive regulation of potassium ion import(GO:1903288)
0.1	1.3	GO:0003334	keratinocyte development(GO:0003334)
0.1	1.1	GO:0032836	glomerular basement membrane development(GO:0032836)
0.1	0.5	GO:0090235	regulation of metaphase plate congression(GO:0090235)
0.1	0.4	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.1	0.3	GO:2000312	regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1	0.4	GO:0043385	mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.1	0.3	GO:0031133	regulation of axon diameter(GO:0031133)
0.1	0.6	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.1	0.1	GO:0060279	positive regulation of ovulation(GO:0060279)
0.1	0.6	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1	0.1	GO:0061300	cerebellum vasculature development(GO:0061300)
0.1	0.7	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.1	0.3	GO:0002545	chronic inflammatory response to non-antigenic stimulus(GO:0002545) positive regulation of chronic inflammatory response(GO:0002678) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
0.1	0.1	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1	0.5	GO:0008215	spermine metabolic process(GO:0008215)
0.1	0.4	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1	0.8	GO:1901898	negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1	0.6	GO:0032049	cardiolipin biosynthetic process(GO:0032049)
0.1	0.3	GO:0018094	protein polyglycylation(GO:0018094)
0.1	0.2	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.1	0.5	GO:1904177	osteoblast fate commitment(GO:0002051) regulation of adipose tissue development(GO:1904177) positive regulation of adipose tissue development(GO:1904179)
0.1	0.6	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654)
0.1	0.3	GO:0060754	positive regulation of mast cell chemotaxis(GO:0060754)
0.1	0.3	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.1	0.3	GO:0038030	non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1	0.2	GO:0071139	resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.1	0.7	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1	1.1	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1	0.4	GO:0006013	mannose metabolic process(GO:0006013)
0.1	0.3	GO:0014004	microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.1	0.5	GO:0046959	habituation(GO:0046959)
0.1	0.3	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.1	0.1	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1	0.4	GO:0033132	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1	0.2	GO:0060382	release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.1	0.3	GO:0045080	positive regulation of chemokine biosynthetic process(GO:0045080)
0.1	0.8	GO:0007258	JUN phosphorylation(GO:0007258)
0.1	0.2	GO:0070914	UV-damage excision repair(GO:0070914)
0.0	0.2	GO:0046391	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0	0.0	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0	0.2	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.0	0.0	GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.0	0.6	GO:0010668	ectodermal cell differentiation(GO:0010668)
0.0	0.2	GO:0036414	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0	0.2	GO:0060729	intestinal epithelial structure maintenance(GO:0060729)
0.0	0.7	GO:0014051	gamma-aminobutyric acid secretion(GO:0014051)
0.0	0.3	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.0	0.7	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.6	GO:0086036	regulation of cardiac muscle cell membrane potential(GO:0086036)
0.0	0.5	GO:0070307	lens fiber cell development(GO:0070307)
0.0	1.3	GO:0035728	response to hepatocyte growth factor(GO:0035728)
0.0	0.7	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.0	0.5	GO:0098535	de novo centriole assembly(GO:0098535)
0.0	0.2	GO:0032290	peripheral nervous system myelin formation(GO:0032290)
0.0	0.5	GO:0071880	adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0	0.8	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.2	GO:1990502	dense core granule maturation(GO:1990502)
0.0	0.1	GO:1901526	positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0	0.8	GO:0016446	somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0	0.2	GO:0031860	telomeric 3' overhang formation(GO:0031860)
0.0	5.2	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0	0.2	GO:0010807	regulation of synaptic vesicle priming(GO:0010807)
0.0	0.5	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0	1.4	GO:0045332	phospholipid translocation(GO:0045332)
0.0	0.8	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.0	0.3	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0	0.3	GO:0051415	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0	0.3	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0	0.4	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.8	GO:1902373	negative regulation of mRNA catabolic process(GO:1902373)
0.0	0.4	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.2	GO:0001923	B-1 B cell differentiation(GO:0001923)
0.0	0.2	GO:0046929	negative regulation of neurotransmitter secretion(GO:0046929)
0.0	0.6	GO:0008090	retrograde axonal transport(GO:0008090)
0.0	0.2	GO:0023016	signal transduction by trans-phosphorylation(GO:0023016)
0.0	0.2	GO:1903758	regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0	0.2	GO:0045048	protein insertion into ER membrane(GO:0045048)
0.0	0.3	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.3	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.3	GO:0021707	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.1	GO:1904116	response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.0	0.1	GO:0090135	actin filament branching(GO:0090135)
0.0	0.7	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.0	0.1	GO:0051643	endoplasmic reticulum localization(GO:0051643)
0.0	0.7	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	0.1	GO:0099553	trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.0	0.3	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0	0.3	GO:0009086	methionine biosynthetic process(GO:0009086)
0.0	0.6	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.2	GO:0086047	membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.0	0.5	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0	1.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.3	GO:0097026	dendritic cell dendrite assembly(GO:0097026)
0.0	0.3	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.0	0.3	GO:0072513	positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0	0.2	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	1.6	GO:1990090	cellular response to nerve growth factor stimulus(GO:1990090)
0.0	0.5	GO:0090161	Golgi ribbon formation(GO:0090161)
0.0	0.1	GO:0018199	peptidyl-glutamine modification(GO:0018199)
0.0	0.5	GO:0043306	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0	0.3	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0	0.2	GO:0048194	Golgi vesicle budding(GO:0048194)
0.0	0.1	GO:0070904	L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.0	1.7	GO:0006692	prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0	0.2	GO:0006196	AMP catabolic process(GO:0006196)
0.0	0.1	GO:0031296	positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.0	0.1	GO:0003057	regulation of the force of heart contraction by chemical signal(GO:0003057)
0.0	1.3	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.0	0.4	GO:0007144	female meiosis I(GO:0007144)
0.0	0.5	GO:0048642	negative regulation of skeletal muscle tissue development(GO:0048642)
0.0	0.7	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.1	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.1	GO:0009439	cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.0	0.1	GO:1903225	negative regulation of endodermal cell differentiation(GO:1903225)
0.0	0.8	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.4	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	2.1	GO:0016574	histone ubiquitination(GO:0016574)
0.0	0.7	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.6	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	1.0	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	1.1	GO:0034142	toll-like receptor 4 signaling pathway(GO:0034142)
0.0	1.2	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0	0.5	GO:0045116	protein neddylation(GO:0045116)
0.0	0.1	GO:2000393	negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0	0.0	GO:0003256	regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003256)
0.0	0.3	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0	0.1	GO:0034472	snRNA 3'-end processing(GO:0034472)
0.0	0.3	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.2	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.2	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0	0.7	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	2.7	GO:0043966	histone H3 acetylation(GO:0043966)
0.0	0.1	GO:0003290	atrial septum secundum morphogenesis(GO:0003290)
0.0	0.2	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.2	GO:0036089	cleavage furrow formation(GO:0036089)
0.0	0.9	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0	0.8	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.6	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.0	0.1	GO:0010796	regulation of multivesicular body size(GO:0010796)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.3	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.3	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.1	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.3	GO:0010042	response to manganese ion(GO:0010042)
0.0	1.3	GO:0045646	regulation of erythrocyte differentiation(GO:0045646)
0.0	0.2	GO:0060295	regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0	0.2	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.0	0.2	GO:0015705	iodide transport(GO:0015705)
0.0	0.5	GO:0006071	glycerol metabolic process(GO:0006071)
0.0	0.1	GO:0072229	proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.0	1.4	GO:0046513	ceramide biosynthetic process(GO:0046513)
0.0	0.2	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.0	0.1	GO:0030576	Cajal body organization(GO:0030576)
0.0	0.2	GO:0070475	rRNA base methylation(GO:0070475)
0.0	0.1	GO:0001189	RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0	1.0	GO:0090102	cochlea development(GO:0090102)
0.0	0.8	GO:0090129	positive regulation of synapse maturation(GO:0090129)
0.0	0.9	GO:0033344	cholesterol efflux(GO:0033344)
0.0	0.3	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0	0.2	GO:2001135	regulation of endocytic recycling(GO:2001135)
0.0	0.1	GO:1905098	regulation of guanyl-nucleotide exchange factor activity(GO:1905097) negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0	0.4	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.3	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.2	GO:0044597	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0	0.1	GO:0015853	adenine transport(GO:0015853)
0.0	0.1	GO:0035720	intraciliary anterograde transport(GO:0035720)
0.0	0.1	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	1.1	GO:0045540	regulation of cholesterol biosynthetic process(GO:0045540)
0.0	1.3	GO:0046626	regulation of insulin receptor signaling pathway(GO:0046626)
0.0	0.6	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	1.0	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0	2.6	GO:0070268	cornification(GO:0070268)
0.0	0.4	GO:0030497	fatty acid elongation(GO:0030497)
0.0	0.3	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.2	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.4	GO:2000651	positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0	0.6	GO:0001893	maternal placenta development(GO:0001893)
0.0	0.4	GO:0097320	membrane tubulation(GO:0097320)
0.0	0.5	GO:0060612	adipose tissue development(GO:0060612)
0.0	0.1	GO:0071286	cellular response to magnesium ion(GO:0071286)
0.0	0.2	GO:0046133	pyrimidine ribonucleoside catabolic process(GO:0046133)
0.0	0.1	GO:0021943	formation of radial glial scaffolds(GO:0021943)
0.0	0.1	GO:1903416	response to glycoside(GO:1903416)
0.0	0.1	GO:0042421	norepinephrine biosynthetic process(GO:0042421)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.2	GO:0035563	positive regulation of chromatin binding(GO:0035563)
0.0	0.4	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	0.1	GO:0071799	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0	0.6	GO:1901570	icosanoid biosynthetic process(GO:0046456) fatty acid derivative biosynthetic process(GO:1901570)
0.0	1.0	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.0	GO:2000584	regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0	0.1	GO:0045872	positive regulation of rhodopsin gene expression(GO:0045872)
0.0	0.1	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.0	0.4	GO:2000505	regulation of energy homeostasis(GO:2000505)
0.0	0.1	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.2	GO:0050961	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.1	GO:0098838	reduced folate transmembrane transport(GO:0098838)
0.0	0.3	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	1.1	GO:0070206	protein trimerization(GO:0070206)
0.0	0.2	GO:0072520	seminiferous tubule development(GO:0072520)
0.0	0.1	GO:0051541	elastin metabolic process(GO:0051541)
0.0	0.1	GO:0019064	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0	0.1	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.0	0.3	GO:0046051	UTP metabolic process(GO:0046051)
0.0	0.1	GO:0015744	succinate transport(GO:0015744) sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221) succinate transmembrane transport(GO:0071422)
0.0	0.3	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	0.3	GO:0005980	glycogen catabolic process(GO:0005980)
0.0	0.4	GO:0044803	multi-organism membrane organization(GO:0044803)
0.0	0.5	GO:0022400	regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0	0.1	GO:0002115	store-operated calcium entry(GO:0002115)
0.0	0.3	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.0	0.2	GO:2000781	positive regulation of double-strand break repair(GO:2000781)
0.0	0.3	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.2	GO:0035810	positive regulation of urine volume(GO:0035810)
0.0	0.0	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0	0.0	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.3	GO:1902884	positive regulation of response to oxidative stress(GO:1902884)
0.0	0.3	GO:0045724	positive regulation of cilium assembly(GO:0045724)
0.0	0.1	GO:0006621	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.0	GO:1903333	regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) regulation of protein folding(GO:1903332) negative regulation of protein folding(GO:1903333)
0.0	0.4	GO:0014003	oligodendrocyte development(GO:0014003)
0.0	0.1	GO:1902410	mitotic cytokinetic process(GO:1902410)
0.0	0.0	GO:1903121	regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0	0.3	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.4	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.1	GO:0080182	histone H3-K4 trimethylation(GO:0080182)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	4.9	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.4	8.3	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
0.4	2.3	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.4	1.8	GO:0048179	activin receptor complex(GO:0048179)
0.3	1.2	GO:0097196	Shu complex(GO:0097196)
0.3	7.2	GO:0031045	dense core granule(GO:0031045)
0.3	3.0	GO:0016589	NURF complex(GO:0016589)
0.3	0.8	GO:0036117	hyaluranon cable(GO:0036117)
0.3	0.8	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.3	3.0	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.2	1.4	GO:0031673	H zone(GO:0031673)
0.2	1.6	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2	0.9	GO:0097629	extrinsic component of omegasome membrane(GO:0097629)
0.2	1.9	GO:0000125	PCAF complex(GO:0000125)
0.2	2.6	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2	0.7	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.2	1.5	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	0.9	GO:0071458	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1	3.2	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.1	0.7	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.1	0.6	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.4	GO:0034657	GID complex(GO:0034657)
0.1	7.2	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.1	1.3	GO:0042587	glycogen granule(GO:0042587)
0.1	0.3	GO:0031251	PAN complex(GO:0031251)
0.1	0.3	GO:1990917	sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917)
0.1	0.8	GO:0043196	varicosity(GO:0043196)
0.1	1.2	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1	2.0	GO:0035102	PRC1 complex(GO:0035102)
0.1	0.6	GO:0020016	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1	0.3	GO:1905103	integral component of lysosomal membrane(GO:1905103)
0.1	2.1	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1	1.4	GO:0000813	ESCRT I complex(GO:0000813)
0.1	0.3	GO:0032449	CBM complex(GO:0032449)
0.1	0.2	GO:0030312	external encapsulating structure(GO:0030312)
0.1	0.7	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1	1.2	GO:0000930	gamma-tubulin complex(GO:0000930)
0.1	0.2	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.1	0.4	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1	1.2	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.2	GO:0000939	condensed chromosome inner kinetochore(GO:0000939)
0.1	0.4	GO:0098837	postsynaptic recycling endosome(GO:0098837)
0.1	1.5	GO:0036020	endolysosome membrane(GO:0036020)
0.1	0.4	GO:1990246	uniplex complex(GO:1990246)
0.1	0.3	GO:0005873	plus-end kinesin complex(GO:0005873)
0.1	0.3	GO:0071595	Nem1-Spo7 phosphatase complex(GO:0071595)
0.1	2.2	GO:0034451	centriolar satellite(GO:0034451)
0.1	1.3	GO:0044232	organelle membrane contact site(GO:0044232)
0.1	0.3	GO:0032301	MutSalpha complex(GO:0032301)
0.1	0.3	GO:0032311	angiogenin-PRI complex(GO:0032311)
0.0	0.5	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.8	GO:0097470	ribbon synapse(GO:0097470)
0.0	0.4	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.8	GO:0061700	GATOR2 complex(GO:0061700)
0.0	0.8	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.2	GO:0019034	viral replication complex(GO:0019034)
0.0	0.9	GO:0060077	inhibitory synapse(GO:0060077)
0.0	1.2	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.2	GO:0097059	CNTFR-CLCF1 complex(GO:0097059)
0.0	1.1	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.3	GO:0031415	NatA complex(GO:0031415)
0.0	4.6	GO:0005905	clathrin-coated pit(GO:0005905)
0.0	0.8	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.7	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.1	GO:0055087	Ski complex(GO:0055087)
0.0	5.1	GO:0042734	presynaptic membrane(GO:0042734)
0.0	1.4	GO:0034361	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0	0.3	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.0	0.6	GO:0031209	SCAR complex(GO:0031209)
0.0	0.5	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	1.2	GO:0030057	desmosome(GO:0030057)
0.0	0.4	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.2	GO:0061673	mitotic spindle astral microtubule(GO:0061673)
0.0	0.5	GO:0005915	zonula adherens(GO:0005915)
0.0	0.2	GO:0000124	SAGA complex(GO:0000124)
0.0	0.1	GO:0042720	mitochondrial inner membrane peptidase complex(GO:0042720)
0.0	0.9	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	0.4	GO:0030478	actin cap(GO:0030478)
0.0	0.2	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.8	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	3.9	GO:0005796	Golgi lumen(GO:0005796)
0.0	3.2	GO:0005581	collagen trimer(GO:0005581)
0.0	0.1	GO:0000814	ESCRT II complex(GO:0000814)
0.0	1.2	GO:0008305	integrin complex(GO:0008305)
0.0	0.1	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.4	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	0.6	GO:0036038	MKS complex(GO:0036038)
0.0	1.5	GO:0097542	ciliary tip(GO:0097542)
0.0	0.8	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.4	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.0	0.2	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0	2.2	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.1	GO:0005610	laminin-5 complex(GO:0005610)
0.0	0.8	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	1.6	GO:0045095	keratin filament(GO:0045095)
0.0	2.4	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.3	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.0	0.2	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.3	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.4	GO:0031143	pseudopodium(GO:0031143)
0.0	2.4	GO:0016459	myosin complex(GO:0016459)
0.0	0.3	GO:0001520	outer dense fiber(GO:0001520)
0.0	0.2	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.0	1.3	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	5.8	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.0	0.3	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.2	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0	2.4	GO:0031985	Golgi cisterna(GO:0031985)
0.0	0.3	GO:0008091	spectrin(GO:0008091)
0.0	0.5	GO:0097381	photoreceptor disc membrane(GO:0097381)
0.0	0.1	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0	0.4	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.4	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.2	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.5	GO:0033202	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0	0.4	GO:0031083	BLOC-1 complex(GO:0031083)
0.0	0.4	GO:0030137	COPI-coated vesicle(GO:0030137)
0.0	0.3	GO:0000145	exocyst(GO:0000145)
0.0	0.9	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.0	1.1	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.0	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.2	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.2	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.2	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.3	GO:0010369	chromocenter(GO:0010369)
0.0	1.9	GO:0101002	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0	0.2	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.4	GO:0005921	gap junction(GO:0005921)
0.0	0.3	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.8	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.1	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.1	GO:1990745	EARP complex(GO:1990745)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	5.4	GO:0050262	ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.7	2.1	GO:0052810	1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.7	2.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.6	3.2	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.6	5.5	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.6	4.3	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.5	0.5	GO:0070097	delta-catenin binding(GO:0070097)
0.5	2.2	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.5	1.5	GO:0004782	sulfinoalanine decarboxylase activity(GO:0004782)
0.5	4.9	GO:0008420	CTD phosphatase activity(GO:0008420)
0.4	1.3	GO:0008424	glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.4	3.2	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.4	1.9	GO:0070573	metallodipeptidase activity(GO:0070573)
0.4	6.4	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.4	1.1	GO:0008903	hydroxypyruvate isomerase activity(GO:0008903)
0.4	1.1	GO:0050613	delta14-sterol reductase activity(GO:0050613)
0.4	1.1	GO:0008476	protein-tyrosine sulfotransferase activity(GO:0008476)
0.4	2.8	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.3	1.7	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.3	1.6	GO:1903135	cupric ion binding(GO:1903135)
0.3	1.2	GO:0003883	CTP synthase activity(GO:0003883)
0.3	2.7	GO:0016206	catechol O-methyltransferase activity(GO:0016206)
0.3	1.2	GO:0034041	sterol-transporting ATPase activity(GO:0034041)
0.3	1.2	GO:0033265	choline binding(GO:0033265)
0.3	1.4	GO:0032184	SUMO polymer binding(GO:0032184)
0.3	1.1	GO:0016524	latrotoxin receptor activity(GO:0016524)
0.3	1.1	GO:0047493	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.3	0.5	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.3	1.8	GO:0016361	activin receptor activity, type I(GO:0016361)
0.2	2.2	GO:0043237	laminin-1 binding(GO:0043237)
0.2	1.0	GO:0048763	calcium-induced calcium release activity(GO:0048763)
0.2	0.9	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
0.2	0.7	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.2	1.8	GO:0036132	13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.2	0.9	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.2	1.1	GO:0003989	acetyl-CoA carboxylase activity(GO:0003989)
0.2	0.6	GO:0051717	inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.2	0.6	GO:0070119	ciliary neurotrophic factor binding(GO:0070119)
0.2	1.6	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2	0.8	GO:0015154	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.2	1.1	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.2	0.7	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.2	1.6	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.2	1.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.2	0.9	GO:0047273	galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.2	0.5	GO:0080023	3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
0.2	0.5	GO:0000248	C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704)
0.2	0.5	GO:0005055	laminin receptor activity(GO:0005055)
0.2	0.8	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.2	1.0	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.2	0.5	GO:0002094	polyprenyltransferase activity(GO:0002094)
0.2	0.8	GO:0031750	D3 dopamine receptor binding(GO:0031750)
0.2	0.5	GO:0010698	acetyltransferase activator activity(GO:0010698)
0.2	1.1	GO:0030267	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.2	0.9	GO:0010465	nerve growth factor receptor activity(GO:0010465)
0.1	1.2	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.1	6.6	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.1	0.7	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1	0.6	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.1	2.9	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1	1.0	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	1.4	GO:0070569	uridylyltransferase activity(GO:0070569)
0.1	1.4	GO:0002161	aminoacyl-tRNA editing activity(GO:0002161)
0.1	2.0	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.1	0.5	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1	0.8	GO:0051996	farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1	0.9	GO:1904288	BAT3 complex binding(GO:1904288)
0.1	0.4	GO:0071209	U7 snRNA binding(GO:0071209)
0.1	0.4	GO:0004566	beta-glucuronidase activity(GO:0004566) heparanase activity(GO:0030305)
0.1	0.6	GO:0043208	glycosphingolipid binding(GO:0043208)
0.1	2.3	GO:0038191	neuropilin binding(GO:0038191)
0.1	0.5	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1	0.8	GO:0004075	biotin carboxylase activity(GO:0004075)
0.1	0.4	GO:0016534	cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1	0.3	GO:1990190	peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.1	0.3	GO:0002135	CTP binding(GO:0002135)
0.1	1.8	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.1	3.9	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.1	0.3	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.1	1.1	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.1	0.3	GO:0008466	glycogenin glucosyltransferase activity(GO:0008466)
0.1	0.4	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1	1.5	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	1.6	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.1	2.0	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.1	1.5	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1	1.0	GO:0015651	quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.1	0.4	GO:0022865	transmembrane electron transfer carrier(GO:0022865)
0.1	0.3	GO:0051990	(R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.1	0.1	GO:0031755	endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.1	0.5	GO:0046624	sphingolipid transporter activity(GO:0046624)
0.1	0.6	GO:0004522	ribonuclease A activity(GO:0004522)
0.1	1.3	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1	0.5	GO:0052844	endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.1	0.7	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.1	0.5	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.1	0.8	GO:0043426	MRF binding(GO:0043426)
0.1	0.5	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.1	1.4	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.1	0.3	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1	0.3	GO:0051011	microtubule minus-end binding(GO:0051011)
0.1	1.3	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	1.7	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.1	1.7	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1	0.4	GO:0097108	hedgehog family protein binding(GO:0097108)
0.1	0.7	GO:0005000	vasopressin receptor activity(GO:0005000)
0.1	1.0	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.1	0.4	GO:0097016	L27 domain binding(GO:0097016)
0.1	1.3	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.2	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	0.3	GO:0044378	non-sequence-specific DNA binding, bending(GO:0044378)
0.1	1.9	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.1	0.3	GO:0003839	gamma-glutamylcyclotransferase activity(GO:0003839)
0.1	0.5	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1	0.4	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.1	0.2	GO:0004174	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1	2.8	GO:0031418	L-ascorbic acid binding(GO:0031418)
0.1	0.5	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1	0.8	GO:0004844	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.1	0.3	GO:0004487	methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.1	0.6	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1	1.0	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1	0.8	GO:0004118	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1	0.6	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.1	0.3	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1	0.8	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1	0.3	GO:0003943	N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1	0.3	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1	0.5	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.1	1.8	GO:0031432	titin binding(GO:0031432)
0.1	0.2	GO:0055100	adiponectin binding(GO:0055100)
0.1	1.7	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	0.3	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1	4.6	GO:0051018	protein kinase A binding(GO:0051018)
0.1	0.4	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.1	0.9	GO:0070492	oligosaccharide binding(GO:0070492)
0.1	0.2	GO:0002060	purine nucleobase binding(GO:0002060) glycogen phosphorylase activity(GO:0008184)
0.1	0.9	GO:0032183	SUMO binding(GO:0032183)
0.1	0.7	GO:0031386	protein tag(GO:0031386)
0.1	2.7	GO:0043015	gamma-tubulin binding(GO:0043015)
0.1	4.3	GO:0005044	scavenger receptor activity(GO:0005044)
0.1	0.6	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1	0.9	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1	0.3	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.1	1.6	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.1	1.5	GO:0043274	phospholipase binding(GO:0043274)
0.1	1.6	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	1.8	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1	0.4	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1	1.6	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1	1.7	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.1	0.7	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
0.1	0.6	GO:0038132	neuregulin binding(GO:0038132)
0.1	1.1	GO:0004707	MAP kinase activity(GO:0004707)
0.1	0.2	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1	0.2	GO:0102345	3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.1	0.4	GO:0070728	leucine binding(GO:0070728)
0.1	0.3	GO:0032143	single thymine insertion binding(GO:0032143)
0.1	2.0	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.1	0.7	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.6	GO:0003996	acyl-CoA ligase activity(GO:0003996)
0.0	0.1	GO:0052739	phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0	0.6	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
0.0	0.3	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.0	1.5	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.2	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.5	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.6	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.4	GO:0004996	thyroid-stimulating hormone receptor activity(GO:0004996)
0.0	1.2	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	1.4	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.2	GO:0016402	pristanoyl-CoA oxidase activity(GO:0016402)
0.0	3.4	GO:0051287	NAD binding(GO:0051287)
0.0	0.4	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.2	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.0	0.3	GO:0051373	FATZ binding(GO:0051373)
0.0	0.2	GO:0016434	rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0	1.3	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0	0.1	GO:0001537	N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0	0.1	GO:0016784	3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.0	1.2	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0	0.9	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.5	GO:0050072	m7G(5')pppN diphosphatase activity(GO:0050072)
0.0	0.6	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.2	GO:0086062	voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0	0.3	GO:0010385	double-stranded methylated DNA binding(GO:0010385)
0.0	0.7	GO:0008391	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0	0.1	GO:0070890	L-ascorbate:sodium symporter activity(GO:0008520) sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0	0.3	GO:0001042	RNA polymerase I core binding(GO:0001042)
0.0	0.7	GO:0005542	folic acid binding(GO:0005542)
0.0	0.1	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.6	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.7	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.7	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.0	0.1	GO:0005471	ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0	0.2	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.6	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.4	GO:0045159	myosin II binding(GO:0045159)
0.0	0.4	GO:0003678	DNA helicase activity(GO:0003678)
0.0	0.6	GO:0051400	BH domain binding(GO:0051400)
0.0	1.4	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.3	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.5	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.3	GO:0036310	annealing helicase activity(GO:0036310)
0.0	0.7	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.0	0.9	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	0.2	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:1904455	ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0	0.2	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	2.9	GO:0008094	DNA-dependent ATPase activity(GO:0008094)
0.0	0.1	GO:0005046	KDEL sequence binding(GO:0005046)
0.0	0.2	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.3	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.1	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0	0.1	GO:0015275	stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.0	0.4	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.0	GO:0004915	interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0	2.5	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.0	0.2	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.2	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.9	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.2	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	5.2	GO:0004721	phosphoprotein phosphatase activity(GO:0004721)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.2	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.7	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.5	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0015140	malate transmembrane transporter activity(GO:0015140)
0.0	5.4	GO:0008022	protein C-terminus binding(GO:0008022)
0.0	0.2	GO:0015926	glucosidase activity(GO:0015926)
0.0	0.1	GO:0044736	acid-sensing ion channel activity(GO:0044736)
0.0	0.2	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.1	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.0	0.1	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.4	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.7	GO:0042165	neurotransmitter binding(GO:0042165)
0.0	0.6	GO:0030552	cAMP binding(GO:0030552)
0.0	0.3	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	0.1	GO:0015440	peptide-transporting ATPase activity(GO:0015440)
0.0	3.1	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	0.3	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.8	GO:0008146	sulfotransferase activity(GO:0008146)
0.0	0.4	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.2	GO:0015386	potassium:proton antiporter activity(GO:0015386)
0.0	0.9	GO:0019894	kinesin binding(GO:0019894)
0.0	0.5	GO:0005158	insulin receptor binding(GO:0005158)
0.0	0.0	GO:0004051	arachidonate 5-lipoxygenase activity(GO:0004051)
0.0	0.4	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.3	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	1.0	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.1	GO:0047066	phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0	0.3	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.2	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	1.3	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0008453	alanine-glyoxylate transaminase activity(GO:0008453)
0.0	0.0	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.2	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.1	GO:0004532	exoribonuclease activity(GO:0004532)
0.0	3.3	GO:0051015	actin filament binding(GO:0051015)
0.0	0.4	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	5.5	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0	0.1	GO:0022821	calcium, potassium:sodium antiporter activity(GO:0008273) potassium ion antiporter activity(GO:0022821)
0.0	0.2	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.3	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.4	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.1	GO:0034618	arginine binding(GO:0034618)
0.0	0.7	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)
0.0	0.1	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.4	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	3.8	GO:0031625	ubiquitin protein ligase binding(GO:0031625)
0.0	0.1	GO:0098639	C-X3-C chemokine binding(GO:0019960) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0	1.5	GO:0005179	hormone activity(GO:0005179)
0.0	0.4	GO:0015269	calcium-activated potassium channel activity(GO:0015269)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.5	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.2	1.0	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.1	0.3	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.1	1.4	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.1	4.0	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	1.9	PID ALK2 PATHWAY	ALK2 signaling events
0.1	8.4	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	7.3	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	3.1	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1	0.9	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.1	3.7	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.1	0.4	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.1	4.0	PID RHOA PATHWAY	RhoA signaling pathway
0.1	0.8	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.6	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.3	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.2	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	1.7	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.7	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.7	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	8.1	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.4	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.3	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	1.2	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	1.8	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.3	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.6	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.4	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.8	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.9	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	2.0	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	2.7	PID E2F PATHWAY	E2F transcription factor network
0.0	1.0	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.9	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	0.1	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	1.9	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.6	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.8	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.3	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	0.2	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.3	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.4	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.5	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.1	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.8	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.4	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.1	PID TXA2PATHWAY	Thromboxane A2 receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.6	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.2	6.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	3.0	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.1	7.3	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.1	2.5	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1	0.8	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.1	5.6	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	3.1	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.1	4.3	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.1	1.2	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	2.6	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.1	1.8	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	1.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.2	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	0.9	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	1.7	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.1	1.0	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	2.8	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	2.5	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.1	1.4	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.1	0.4	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	0.6	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	1.9	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	0.1	REACTOME SIGNALING BY GPCR	Genes involved in Signaling by GPCR
0.1	0.2	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	1.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	1.8	REACTOME KINESINS	Genes involved in Kinesins
0.0	1.5	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.8	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	1.4	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	1.2	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	1.5	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.3	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	4.0	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	1.3	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	1.0	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.6	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.6	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.6	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.5	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	1.3	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	1.0	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.8	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	3.6	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.9	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	2.9	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	0.6	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.3	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.6	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	1.0	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.6	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.9	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	1.3	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.5	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	1.1	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.4	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	1.0	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.3	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.6	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.5	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.2	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	0.9	REACTOME ION CHANNEL TRANSPORT	Genes involved in Ion channel transport
0.0	0.4	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.6	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	1.6	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.4	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.4	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.6	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.3	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.4	REACTOME SIGNALING BY FGFR MUTANTS	Genes involved in Signaling by FGFR mutants
0.0	0.1	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.3	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.2	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.7	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.7	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.6	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription

Results for HIC1

Z-value: 1.13

Motif logo

Transcription factors associated with HIC1

Activity-expression correlation:

Activity profile of HIC1 motif

Sorted Z-values of HIC1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HIC1

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: