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Inflammatory response time course, HUVEC (Wada, 2009)
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Results for HIVEP1
Z-value: 1.74
Motif logo
Transcription factors associated with HIVEP1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
HIVEP1
|
ENSG00000095951.17 | HIVEP1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HIVEP1 | hg38_v1_chr6_+_12012304_12012338 | 0.44 | 2.7e-02 | Click! |
Activity profile of HIVEP1 motif
Sorted Z-values of HIVEP1 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of HIVEP1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.4 | 17.0 | GO:0000255 | allantoin metabolic process(GO:0000255) |
| 2.2 | 6.6 | GO:0034147 | regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) |
| 1.8 | 5.4 | GO:0061394 | regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) |
| 1.7 | 5.2 | GO:0052027 | modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032) |
| 1.6 | 8.1 | GO:0034344 | type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) |
| 1.5 | 15.2 | GO:0002480 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480) |
| 1.1 | 4.5 | GO:0002296 | T-helper 1 cell lineage commitment(GO:0002296) |
| 1.1 | 6.7 | GO:2001180 | negative regulation of interleukin-10 secretion(GO:2001180) |
| 1.1 | 11.7 | GO:0043950 | positive regulation of cAMP-mediated signaling(GO:0043950) |
| 0.9 | 8.0 | GO:0032713 | negative regulation of interleukin-4 production(GO:0032713) |
| 0.8 | 5.8 | GO:0033590 | response to cobalamin(GO:0033590) cellular response to erythropoietin(GO:0036018) |
| 0.8 | 5.4 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
| 0.8 | 3.0 | GO:0032499 | detection of peptidoglycan(GO:0032499) activation of MAPK activity involved in innate immune response(GO:0035419) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) |
| 0.7 | 9.1 | GO:0032782 | bile acid secretion(GO:0032782) |
| 0.6 | 1.9 | GO:0045212 | negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212) |
| 0.6 | 20.6 | GO:0090023 | positive regulation of neutrophil chemotaxis(GO:0090023) |
| 0.6 | 4.3 | GO:2000857 | positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860) |
| 0.6 | 4.5 | GO:0042699 | follicle-stimulating hormone signaling pathway(GO:0042699) |
| 0.5 | 8.0 | GO:0045078 | positive regulation of interferon-gamma biosynthetic process(GO:0045078) |
| 0.5 | 3.1 | GO:1903936 | cellular response to sodium arsenite(GO:1903936) |
| 0.5 | 1.9 | GO:0060448 | dichotomous subdivision of terminal units involved in lung branching(GO:0060448) |
| 0.5 | 4.3 | GO:2001199 | negative regulation of dendritic cell differentiation(GO:2001199) |
| 0.5 | 3.7 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
| 0.4 | 7.6 | GO:0042940 | D-amino acid transport(GO:0042940) |
| 0.4 | 1.7 | GO:1901842 | negative regulation of high voltage-gated calcium channel activity(GO:1901842) |
| 0.4 | 2.5 | GO:2000158 | positive regulation of ubiquitin-specific protease activity(GO:2000158) |
| 0.4 | 3.3 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.4 | 2.0 | GO:0071393 | cellular response to progesterone stimulus(GO:0071393) |
| 0.4 | 5.2 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 0.3 | 1.0 | GO:0070427 | nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427) |
| 0.3 | 1.0 | GO:1902214 | negative regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034125) regulation of interleukin-4-mediated signaling pathway(GO:1902214) |
| 0.3 | 5.3 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.3 | 7.8 | GO:0045063 | T-helper 1 cell differentiation(GO:0045063) |
| 0.3 | 1.9 | GO:0051106 | positive regulation of DNA ligation(GO:0051106) |
| 0.3 | 1.2 | GO:0035880 | embryonic nail plate morphogenesis(GO:0035880) activation of meiosis(GO:0090427) |
| 0.3 | 0.6 | GO:0009726 | detection of endogenous stimulus(GO:0009726) |
| 0.3 | 1.6 | GO:0060370 | susceptibility to T cell mediated cytotoxicity(GO:0060370) |
| 0.3 | 1.9 | GO:0051684 | maintenance of Golgi location(GO:0051684) double-strand break repair via classical nonhomologous end joining(GO:0097680) |
| 0.3 | 1.3 | GO:0045875 | negative regulation of sister chromatid cohesion(GO:0045875) |
| 0.3 | 0.8 | GO:0001544 | initiation of primordial ovarian follicle growth(GO:0001544) |
| 0.3 | 1.3 | GO:0071918 | urea transmembrane transport(GO:0071918) |
| 0.3 | 0.8 | GO:0060578 | subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578) |
| 0.3 | 1.3 | GO:2001034 | positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034) |
| 0.3 | 1.0 | GO:1903519 | apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747) |
| 0.2 | 2.1 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 0.2 | 1.4 | GO:0019264 | glycine biosynthetic process from serine(GO:0019264) |
| 0.2 | 1.8 | GO:0060154 | cellular process regulating host cell cycle in response to virus(GO:0060154) |
| 0.2 | 0.8 | GO:0033031 | positive regulation of neutrophil apoptotic process(GO:0033031) |
| 0.2 | 2.2 | GO:0035585 | calcium-mediated signaling using extracellular calcium source(GO:0035585) |
| 0.2 | 0.8 | GO:1904732 | regulation of electron carrier activity(GO:1904732) |
| 0.2 | 0.7 | GO:2000077 | negative regulation of dopaminergic neuron differentiation(GO:1904339) negative regulation of type B pancreatic cell development(GO:2000077) |
| 0.2 | 1.7 | GO:0035897 | proteolysis in other organism(GO:0035897) |
| 0.2 | 0.5 | GO:0051695 | actin filament uncapping(GO:0051695) |
| 0.2 | 0.7 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
| 0.2 | 1.2 | GO:0038110 | interleukin-2-mediated signaling pathway(GO:0038110) |
| 0.2 | 0.7 | GO:0018008 | N-terminal peptidyl-glycine N-myristoylation(GO:0018008) |
| 0.2 | 2.0 | GO:2001288 | positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 0.2 | 1.5 | GO:1903142 | positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
| 0.2 | 1.5 | GO:0006335 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.2 | 4.2 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.2 | 17.9 | GO:0050672 | negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672) |
| 0.2 | 1.3 | GO:0061709 | reticulophagy(GO:0061709) |
| 0.2 | 4.2 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.1 | 0.4 | GO:0001560 | regulation of cell growth by extracellular stimulus(GO:0001560) |
| 0.1 | 1.2 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.1 | 0.7 | GO:0007406 | negative regulation of neuroblast proliferation(GO:0007406) |
| 0.1 | 2.3 | GO:0006878 | cellular copper ion homeostasis(GO:0006878) |
| 0.1 | 0.9 | GO:0031133 | regulation of axon diameter(GO:0031133) |
| 0.1 | 8.1 | GO:1901998 | toxin transport(GO:1901998) |
| 0.1 | 4.4 | GO:0042347 | negative regulation of NF-kappaB import into nucleus(GO:0042347) |
| 0.1 | 0.9 | GO:0006651 | diacylglycerol biosynthetic process(GO:0006651) |
| 0.1 | 0.6 | GO:0043128 | regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128) |
| 0.1 | 0.4 | GO:0070093 | negative regulation of glucagon secretion(GO:0070093) |
| 0.1 | 1.0 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
| 0.1 | 0.6 | GO:2001184 | positive regulation of interleukin-12 secretion(GO:2001184) |
| 0.1 | 2.1 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
| 0.1 | 1.3 | GO:2000645 | negative regulation of receptor catabolic process(GO:2000645) |
| 0.1 | 1.2 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.1 | 5.7 | GO:1902230 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230) |
| 0.1 | 0.3 | GO:0002503 | peptide antigen assembly with MHC class II protein complex(GO:0002503) |
| 0.1 | 4.1 | GO:1904659 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
| 0.1 | 0.7 | GO:0035234 | ectopic germ cell programmed cell death(GO:0035234) pyroptosis(GO:0070269) |
| 0.1 | 0.8 | GO:0097039 | protein linear polyubiquitination(GO:0097039) |
| 0.1 | 0.5 | GO:0060437 | lung growth(GO:0060437) |
| 0.1 | 0.5 | GO:0010813 | neuropeptide catabolic process(GO:0010813) |
| 0.1 | 0.3 | GO:1904899 | regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922) |
| 0.1 | 1.3 | GO:0048298 | positive regulation of isotype switching to IgA isotypes(GO:0048298) |
| 0.1 | 0.5 | GO:0010513 | positive regulation of phosphatidylinositol biosynthetic process(GO:0010513) |
| 0.1 | 1.1 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 0.1 | 1.4 | GO:1990573 | potassium ion import across plasma membrane(GO:1990573) |
| 0.1 | 0.9 | GO:0086024 | adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024) |
| 0.1 | 0.7 | GO:0060681 | branch elongation involved in ureteric bud branching(GO:0060681) |
| 0.1 | 0.5 | GO:0061743 | motor learning(GO:0061743) |
| 0.1 | 7.8 | GO:0010803 | regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803) |
| 0.1 | 0.6 | GO:1900264 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 0.1 | 0.9 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.1 | 0.4 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 0.1 | 0.9 | GO:2000002 | negative regulation of DNA damage checkpoint(GO:2000002) |
| 0.1 | 1.3 | GO:1903071 | positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071) |
| 0.1 | 0.8 | GO:0035524 | proline transmembrane transport(GO:0035524) |
| 0.1 | 0.8 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
| 0.1 | 3.2 | GO:0003016 | respiratory system process(GO:0003016) |
| 0.1 | 0.4 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 0.1 | 0.4 | GO:0032849 | positive regulation of cellular pH reduction(GO:0032849) |
| 0.1 | 1.2 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.1 | 3.9 | GO:0019835 | cytolysis(GO:0019835) |
| 0.1 | 0.3 | GO:1900108 | negative regulation of nodal signaling pathway(GO:1900108) |
| 0.1 | 0.2 | GO:0042631 | cellular response to water deprivation(GO:0042631) |
| 0.1 | 0.3 | GO:0010446 | response to alkaline pH(GO:0010446) |
| 0.1 | 0.5 | GO:0016344 | meiotic chromosome movement towards spindle pole(GO:0016344) |
| 0.1 | 2.3 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.1 | 0.3 | GO:0042488 | positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141) |
| 0.1 | 1.0 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.1 | 2.2 | GO:0046475 | glycerophospholipid catabolic process(GO:0046475) |
| 0.1 | 0.4 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
| 0.1 | 0.2 | GO:1900169 | regulation of glucocorticoid mediated signaling pathway(GO:1900169) |
| 0.1 | 0.3 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
| 0.1 | 0.6 | GO:0042487 | regulation of odontogenesis of dentin-containing tooth(GO:0042487) |
| 0.1 | 2.5 | GO:0043124 | negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124) |
| 0.1 | 0.6 | GO:0048743 | positive regulation of skeletal muscle fiber development(GO:0048743) |
| 0.1 | 3.6 | GO:0042531 | positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531) |
| 0.1 | 1.5 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.0 | 2.0 | GO:0071800 | podosome assembly(GO:0071800) |
| 0.0 | 0.2 | GO:0055118 | negative regulation of cardiac muscle contraction(GO:0055118) |
| 0.0 | 0.1 | GO:0034963 | box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258) |
| 0.0 | 1.9 | GO:0032469 | endoplasmic reticulum calcium ion homeostasis(GO:0032469) |
| 0.0 | 0.6 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
| 0.0 | 0.1 | GO:1902732 | positive regulation of chondrocyte proliferation(GO:1902732) |
| 0.0 | 0.4 | GO:0045329 | carnitine biosynthetic process(GO:0045329) |
| 0.0 | 0.1 | GO:0060392 | negative regulation of SMAD protein import into nucleus(GO:0060392) |
| 0.0 | 0.7 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
| 0.0 | 0.5 | GO:0033690 | positive regulation of osteoblast proliferation(GO:0033690) |
| 0.0 | 3.7 | GO:0070098 | chemokine-mediated signaling pathway(GO:0070098) |
| 0.0 | 0.4 | GO:0002024 | diet induced thermogenesis(GO:0002024) negative regulation of feeding behavior(GO:2000252) |
| 0.0 | 0.7 | GO:1904259 | regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
| 0.0 | 0.6 | GO:0090136 | epithelial cell-cell adhesion(GO:0090136) |
| 0.0 | 1.1 | GO:0045730 | respiratory burst(GO:0045730) |
| 0.0 | 0.7 | GO:0034374 | low-density lipoprotein particle remodeling(GO:0034374) |
| 0.0 | 0.1 | GO:0010041 | response to iron(III) ion(GO:0010041) |
| 0.0 | 0.1 | GO:0006408 | snRNA export from nucleus(GO:0006408) |
| 0.0 | 0.5 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
| 0.0 | 0.6 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 0.0 | 0.8 | GO:0036150 | phosphatidylserine acyl-chain remodeling(GO:0036150) |
| 0.0 | 0.4 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
| 0.0 | 0.4 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
| 0.0 | 0.7 | GO:0048305 | immunoglobulin secretion(GO:0048305) |
| 0.0 | 1.3 | GO:0042026 | protein refolding(GO:0042026) |
| 0.0 | 1.2 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.0 | 0.5 | GO:0034629 | cellular protein complex localization(GO:0034629) |
| 0.0 | 2.8 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.0 | 1.3 | GO:0007080 | mitotic metaphase plate congression(GO:0007080) |
| 0.0 | 1.0 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
| 0.0 | 0.2 | GO:1903659 | regulation of complement-dependent cytotoxicity(GO:1903659) |
| 0.0 | 0.7 | GO:0050962 | detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) |
| 0.0 | 0.2 | GO:0070127 | tRNA aminoacylation for mitochondrial protein translation(GO:0070127) |
| 0.0 | 1.0 | GO:0035338 | long-chain fatty-acyl-CoA biosynthetic process(GO:0035338) |
| 0.0 | 0.7 | GO:0045648 | positive regulation of erythrocyte differentiation(GO:0045648) |
| 0.0 | 0.2 | GO:0051001 | negative regulation of nitric-oxide synthase activity(GO:0051001) |
| 0.0 | 0.6 | GO:0043584 | nose development(GO:0043584) |
| 0.0 | 0.2 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) |
| 0.0 | 0.2 | GO:0051683 | establishment of Golgi localization(GO:0051683) |
| 0.0 | 0.2 | GO:1904715 | negative regulation of chaperone-mediated autophagy(GO:1904715) |
| 0.0 | 0.5 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.0 | 0.5 | GO:0043923 | positive regulation by host of viral transcription(GO:0043923) |
| 0.0 | 2.1 | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) |
| 0.0 | 0.6 | GO:0016578 | histone deubiquitination(GO:0016578) |
| 0.0 | 0.2 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.0 | 0.7 | GO:0070266 | necroptotic process(GO:0070266) |
| 0.0 | 0.8 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 0.0 | 0.4 | GO:0098743 | cell aggregation(GO:0098743) |
| 0.0 | 1.0 | GO:0032922 | circadian regulation of gene expression(GO:0032922) |
| 0.0 | 0.7 | GO:0043666 | regulation of phosphoprotein phosphatase activity(GO:0043666) |
| 0.0 | 0.2 | GO:0035860 | glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860) |
| 0.0 | 0.2 | GO:1902004 | positive regulation of beta-amyloid formation(GO:1902004) |
| 0.0 | 1.1 | GO:0007004 | telomere maintenance via telomerase(GO:0007004) |
| 0.0 | 0.1 | GO:0008050 | negative regulation of female receptivity(GO:0007621) female courtship behavior(GO:0008050) |
| 0.0 | 1.2 | GO:0010595 | positive regulation of endothelial cell migration(GO:0010595) |
| 0.0 | 0.2 | GO:1901741 | positive regulation of myoblast fusion(GO:1901741) |
| 0.0 | 0.8 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 1.4 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 0.0 | 0.7 | GO:0043550 | regulation of lipid kinase activity(GO:0043550) |
| 0.0 | 1.1 | GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479) |
| 0.0 | 2.2 | GO:0008277 | regulation of G-protein coupled receptor protein signaling pathway(GO:0008277) |
| 0.0 | 0.4 | GO:0046850 | regulation of bone remodeling(GO:0046850) |
| 0.0 | 0.3 | GO:0097150 | neuronal stem cell population maintenance(GO:0097150) |
| 0.0 | 1.5 | GO:0002062 | chondrocyte differentiation(GO:0002062) |
| 0.0 | 0.1 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 0.0 | 1.3 | GO:0007631 | feeding behavior(GO:0007631) |
| 0.0 | 0.6 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.0 | 0.1 | GO:1901623 | regulation of lymphocyte chemotaxis(GO:1901623) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 5.4 | GO:1990622 | CHOP-ATF3 complex(GO:1990622) |
| 1.4 | 15.2 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 0.6 | 5.2 | GO:0043196 | varicosity(GO:0043196) |
| 0.6 | 4.2 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.6 | 8.7 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.6 | 4.4 | GO:0098559 | cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560) |
| 0.5 | 2.7 | GO:0045160 | myosin I complex(GO:0045160) |
| 0.3 | 1.6 | GO:0072557 | IPAF inflammasome complex(GO:0072557) AIM2 inflammasome complex(GO:0097169) |
| 0.2 | 0.9 | GO:0097629 | extrinsic component of omegasome membrane(GO:0097629) |
| 0.2 | 5.9 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.2 | 1.3 | GO:1990037 | Lewy body core(GO:1990037) |
| 0.2 | 5.3 | GO:0000145 | exocyst(GO:0000145) |
| 0.2 | 1.9 | GO:0097208 | alveolar lamellar body(GO:0097208) |
| 0.2 | 2.3 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.2 | 1.5 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
| 0.1 | 2.3 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.1 | 1.4 | GO:0070552 | BRISC complex(GO:0070552) |
| 0.1 | 1.3 | GO:0001939 | female pronucleus(GO:0001939) male pronucleus(GO:0001940) |
| 0.1 | 1.1 | GO:0032010 | phagolysosome(GO:0032010) |
| 0.1 | 0.7 | GO:0035841 | new growing cell tip(GO:0035841) |
| 0.1 | 1.9 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.1 | 1.7 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.1 | 2.1 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.1 | 1.9 | GO:0030897 | HOPS complex(GO:0030897) |
| 0.1 | 0.7 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
| 0.1 | 0.5 | GO:0031302 | intrinsic component of endosome membrane(GO:0031302) |
| 0.1 | 2.2 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.1 | 1.7 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.1 | 37.7 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.1 | 0.3 | GO:0036284 | tubulobulbar complex(GO:0036284) |
| 0.1 | 1.2 | GO:0070775 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.1 | 1.0 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.1 | 0.6 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 0.1 | 0.7 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 0.1 | 0.1 | GO:0072536 | interleukin-23 receptor complex(GO:0072536) |
| 0.1 | 0.3 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.1 | 1.5 | GO:0036038 | MKS complex(GO:0036038) |
| 0.1 | 5.1 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.1 | 0.9 | GO:0042555 | MCM complex(GO:0042555) |
| 0.1 | 0.5 | GO:0016011 | dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012) |
| 0.1 | 0.6 | GO:0005879 | axonemal microtubule(GO:0005879) |
| 0.0 | 0.5 | GO:0030478 | actin cap(GO:0030478) |
| 0.0 | 0.6 | GO:0060091 | kinocilium(GO:0060091) |
| 0.0 | 6.0 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 1.7 | GO:0030673 | axolemma(GO:0030673) |
| 0.0 | 0.8 | GO:0033010 | paranodal junction(GO:0033010) |
| 0.0 | 1.3 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 0.3 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
| 0.0 | 0.3 | GO:0097165 | nuclear stress granule(GO:0097165) |
| 0.0 | 0.5 | GO:0000445 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.0 | 0.8 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.0 | 0.7 | GO:0045180 | basal cortex(GO:0045180) |
| 0.0 | 2.5 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 5.0 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 1.9 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.0 | 0.8 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.0 | 0.5 | GO:0044354 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.0 | 0.4 | GO:0016589 | NURF complex(GO:0016589) |
| 0.0 | 7.5 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.0 | 0.7 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.0 | 1.3 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.0 | 2.2 | GO:0005771 | multivesicular body(GO:0005771) |
| 0.0 | 0.5 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.0 | 1.1 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.0 | 1.1 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.0 | 0.8 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.0 | 1.9 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 0.2 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.0 | 0.8 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.0 | 0.2 | GO:0044326 | dendritic spine neck(GO:0044326) |
| 0.0 | 0.6 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.0 | 0.8 | GO:0005839 | proteasome core complex(GO:0005839) |
| 0.0 | 0.7 | GO:0031312 | extrinsic component of organelle membrane(GO:0031312) |
| 0.0 | 0.2 | GO:0098575 | lumenal side of lysosomal membrane(GO:0098575) |
| 0.0 | 0.3 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.0 | 1.4 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 1.6 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 0.1 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
| 0.0 | 3.7 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.0 | 1.6 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.0 | 0.1 | GO:0000221 | vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) |
| 0.0 | 0.3 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.0 | 0.1 | GO:0097123 | cyclin A1-CDK2 complex(GO:0097123) |
| 0.0 | 0.6 | GO:0034704 | calcium channel complex(GO:0034704) |
| 0.0 | 1.8 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 1.3 | GO:0072686 | mitotic spindle(GO:0072686) |
| 0.0 | 0.2 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.0 | 0.3 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.0 | 4.2 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 12.9 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.0 | 0.1 | GO:0030061 | mitochondrial crista(GO:0030061) |
| 0.0 | 1.3 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.0 | 0.5 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.0 | 1.7 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 0.8 | GO:0031907 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 0.4 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 0.2 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.0 | 1.2 | GO:0031902 | late endosome membrane(GO:0031902) |
| 0.0 | 1.9 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 0.1 | GO:0000346 | transcription export complex(GO:0000346) |
| 0.0 | 0.1 | GO:1990907 | beta-catenin-TCF complex(GO:1990907) |
| 0.0 | 2.4 | GO:0034399 | nuclear periphery(GO:0034399) |
| 0.0 | 2.2 | GO:0000775 | chromosome, centromeric region(GO:0000775) |
| 0.0 | 1.1 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.0 | 0.1 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 0.0 | 1.4 | GO:0005884 | actin filament(GO:0005884) |
| 0.0 | 0.2 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.4 | 12.1 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
| 2.1 | 20.6 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 1.5 | 4.5 | GO:0031896 | V2 vasopressin receptor binding(GO:0031896) |
| 0.8 | 6.2 | GO:0046979 | TAP2 binding(GO:0046979) |
| 0.8 | 2.3 | GO:0009032 | thymidine phosphorylase activity(GO:0009032) pyrimidine-nucleoside phosphorylase activity(GO:0016154) |
| 0.7 | 2.8 | GO:0004307 | ethanolaminephosphotransferase activity(GO:0004307) |
| 0.7 | 9.4 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.6 | 4.4 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
| 0.5 | 5.7 | GO:0019958 | C-X-C chemokine binding(GO:0019958) |
| 0.5 | 9.2 | GO:0031996 | thioesterase binding(GO:0031996) |
| 0.5 | 1.9 | GO:0003990 | acetylcholinesterase activity(GO:0003990) |
| 0.4 | 2.5 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
| 0.4 | 12.8 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.4 | 2.6 | GO:0005280 | hydrogen:amino acid symporter activity(GO:0005280) |
| 0.4 | 12.5 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.3 | 1.0 | GO:1902271 | D3 vitamins binding(GO:1902271) |
| 0.3 | 4.9 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 0.3 | 1.3 | GO:0015265 | urea channel activity(GO:0015265) |
| 0.3 | 1.0 | GO:0005136 | interleukin-4 receptor binding(GO:0005136) |
| 0.3 | 0.8 | GO:0052739 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) |
| 0.2 | 1.4 | GO:0042392 | sphingosine-1-phosphate phosphatase activity(GO:0042392) |
| 0.2 | 4.0 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.2 | 5.2 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.2 | 1.4 | GO:0004793 | glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
| 0.2 | 7.4 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.2 | 2.7 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.2 | 0.6 | GO:0031862 | prostanoid receptor binding(GO:0031862) |
| 0.2 | 1.5 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.2 | 3.7 | GO:0048185 | activin binding(GO:0048185) I-SMAD binding(GO:0070411) |
| 0.2 | 1.2 | GO:0086089 | voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089) |
| 0.2 | 6.9 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 0.2 | 0.7 | GO:0019107 | glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107) |
| 0.2 | 1.2 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
| 0.1 | 1.2 | GO:0051373 | FATZ binding(GO:0051373) |
| 0.1 | 2.2 | GO:0019957 | C-C chemokine binding(GO:0019957) |
| 0.1 | 0.4 | GO:0004980 | melanocyte-stimulating hormone receptor activity(GO:0004980) |
| 0.1 | 1.7 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.1 | 2.2 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
| 0.1 | 0.8 | GO:0005298 | proline:sodium symporter activity(GO:0005298) |
| 0.1 | 1.9 | GO:0032393 | MHC class I receptor activity(GO:0032393) |
| 0.1 | 1.2 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 0.1 | 0.4 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 0.1 | 0.9 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
| 0.1 | 0.4 | GO:0098640 | integrin binding involved in cell-matrix adhesion(GO:0098640) |
| 0.1 | 5.7 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.1 | 0.8 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.1 | 2.0 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.1 | 2.5 | GO:0032183 | SUMO binding(GO:0032183) |
| 0.1 | 3.0 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.1 | 2.7 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.1 | 0.4 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
| 0.1 | 0.3 | GO:0001601 | peptide YY receptor activity(GO:0001601) |
| 0.1 | 1.1 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 0.1 | 1.0 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.1 | 0.8 | GO:0016531 | copper chaperone activity(GO:0016531) |
| 0.1 | 1.1 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.1 | 2.0 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) sodium channel inhibitor activity(GO:0019871) |
| 0.1 | 4.7 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.1 | 0.8 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.1 | 0.2 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
| 0.1 | 0.8 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.1 | 1.9 | GO:0003906 | DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906) |
| 0.1 | 3.5 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.1 | 1.8 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.1 | 1.0 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.1 | 0.6 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.1 | 1.1 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
| 0.1 | 8.5 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.1 | 1.2 | GO:0005537 | mannose binding(GO:0005537) |
| 0.1 | 2.5 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.1 | 0.3 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.1 | 1.2 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.1 | 1.5 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.1 | 1.0 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.0 | 0.3 | GO:0031849 | olfactory receptor binding(GO:0031849) |
| 0.0 | 1.3 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 0.1 | GO:1990259 | protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259) |
| 0.0 | 1.5 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
| 0.0 | 0.6 | GO:1990459 | transferrin receptor binding(GO:1990459) |
| 0.0 | 0.7 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
| 0.0 | 1.8 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.0 | 6.8 | GO:0004896 | cytokine receptor activity(GO:0004896) |
| 0.0 | 1.7 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.0 | 0.8 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 0.0 | 0.6 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.0 | 0.5 | GO:0043176 | amine binding(GO:0043176) serotonin binding(GO:0051378) |
| 0.0 | 0.1 | GO:0008988 | rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) |
| 0.0 | 1.0 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
| 0.0 | 0.3 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
| 0.0 | 0.8 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.0 | 0.2 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.0 | 1.5 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.0 | 0.5 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.0 | 1.3 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.0 | 0.6 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.0 | 0.3 | GO:0017040 | ceramidase activity(GO:0017040) |
| 0.0 | 0.9 | GO:0031698 | beta-2 adrenergic receptor binding(GO:0031698) |
| 0.0 | 0.3 | GO:0050682 | AF-2 domain binding(GO:0050682) |
| 0.0 | 0.2 | GO:0016416 | O-palmitoyltransferase activity(GO:0016416) |
| 0.0 | 0.1 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
| 0.0 | 1.5 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
| 0.0 | 0.7 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.0 | 6.2 | GO:0019903 | protein phosphatase binding(GO:0019903) |
| 0.0 | 0.7 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.0 | 1.3 | GO:0004622 | lysophospholipase activity(GO:0004622) |
| 0.0 | 0.3 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.0 | 0.2 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 0.0 | 1.1 | GO:0017147 | Wnt-protein binding(GO:0017147) |
| 0.0 | 0.3 | GO:0016713 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713) |
| 0.0 | 1.4 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.0 | 0.8 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.0 | 0.4 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.0 | 10.7 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.0 | 0.9 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.0 | 2.1 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.0 | 1.0 | GO:0015026 | coreceptor activity(GO:0015026) |
| 0.0 | 0.2 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
| 0.0 | 6.5 | GO:0004713 | protein tyrosine kinase activity(GO:0004713) |
| 0.0 | 0.3 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.0 | 3.0 | GO:0005518 | collagen binding(GO:0005518) |
| 0.0 | 0.2 | GO:1990239 | steroid hormone binding(GO:1990239) |
| 0.0 | 0.2 | GO:0004308 | exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) |
| 0.0 | 0.5 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.0 | 0.1 | GO:0019862 | IgA binding(GO:0019862) |
| 0.0 | 0.5 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.0 | 0.4 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.0 | 1.8 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.0 | 0.2 | GO:0022820 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.0 | 0.6 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.0 | 1.5 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.0 | 2.9 | GO:0000149 | SNARE binding(GO:0000149) |
| 0.0 | 1.3 | GO:0002039 | p53 binding(GO:0002039) |
| 0.0 | 1.6 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 0.7 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.0 | 0.1 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
| 0.0 | 0.1 | GO:0070576 | vitamin D 24-hydroxylase activity(GO:0070576) |
| 0.0 | 0.2 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.0 | 0.2 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.0 | 0.1 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.0 | 0.8 | GO:0043130 | ubiquitin binding(GO:0043130) |
| 0.0 | 0.3 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.0 | 0.3 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 0.0 | 0.6 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.0 | 0.2 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.0 | 1.1 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.0 | 0.1 | GO:0030284 | estrogen receptor activity(GO:0030284) |
| 0.0 | 0.2 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.0 | 0.3 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.0 | 0.5 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.0 | 0.5 | GO:0003774 | motor activity(GO:0003774) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 17.0 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.4 | 25.2 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.3 | 9.0 | ST G ALPHA I PATHWAY | G alpha i Pathway |
| 0.3 | 9.2 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.3 | 9.2 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.3 | 15.5 | PID CXCR3 PATHWAY | CXCR3-mediated signaling events |
| 0.2 | 4.2 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.2 | 7.9 | ST GAQ PATHWAY | G alpha q Pathway |
| 0.2 | 13.0 | PID IL12 2PATHWAY | IL12-mediated signaling events |
| 0.1 | 5.7 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 0.1 | 1.7 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.1 | 1.7 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.1 | 0.8 | SIG IL4RECEPTOR IN B LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.1 | 5.9 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.1 | 1.0 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.1 | 2.6 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.1 | 6.7 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.1 | 1.9 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.1 | 4.2 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 0.1 | 1.3 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.1 | 1.1 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 0.0 | 19.0 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 1.5 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 0.0 | 2.3 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 0.1 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 0.0 | 1.6 | PID ATR PATHWAY | ATR signaling pathway |
| 0.0 | 0.3 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.0 | 1.0 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 0.2 | SA PTEN PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.0 | 1.8 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.0 | 0.4 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 0.6 | SIG BCR SIGNALING PATHWAY | Members of the BCR signaling pathway |
| 0.0 | 0.4 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.0 | 1.3 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 0.3 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.0 | 0.3 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 0.4 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.0 | 0.7 | PID RAC1 PATHWAY | RAC1 signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 15.2 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 0.9 | 18.2 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.5 | 34.5 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.4 | 9.3 | REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
| 0.3 | 1.7 | REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.2 | 11.2 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.2 | 4.9 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.2 | 4.1 | REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX | Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex |
| 0.2 | 6.7 | REACTOME ACTIVATION OF GENES BY ATF4 | Genes involved in Activation of Genes by ATF4 |
| 0.2 | 3.7 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.1 | 4.5 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.1 | 0.4 | REACTOME CD28 DEPENDENT PI3K AKT SIGNALING | Genes involved in CD28 dependent PI3K/Akt signaling |
| 0.1 | 2.3 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |
| 0.1 | 3.3 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.1 | 1.5 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
| 0.1 | 1.2 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.1 | 1.5 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.1 | 1.1 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.1 | 1.2 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.1 | 1.7 | REACTOME INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.1 | 2.5 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.1 | 1.5 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.1 | 4.6 | REACTOME G ALPHA Z SIGNALLING EVENTS | Genes involved in G alpha (z) signalling events |
| 0.1 | 1.0 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.1 | 0.9 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.1 | 7.2 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
| 0.1 | 1.6 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.1 | 2.0 | REACTOME GPVI MEDIATED ACTIVATION CASCADE | Genes involved in GPVI-mediated activation cascade |
| 0.0 | 1.8 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 1.3 | REACTOME ACTIVATED POINT MUTANTS OF FGFR2 | Genes involved in Activated point mutants of FGFR2 |
| 0.0 | 1.0 | REACTOME CD28 DEPENDENT VAV1 PATHWAY | Genes involved in CD28 dependent Vav1 pathway |
| 0.0 | 0.6 | REACTOME POL SWITCHING | Genes involved in Polymerase switching |
| 0.0 | 1.3 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.0 | 0.7 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.0 | 0.5 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 0.0 | 3.9 | REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | Genes involved in Downstream signal transduction |
| 0.0 | 1.6 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.0 | 0.8 | REACTOME RNA POL III CHAIN ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 0.0 | 1.0 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 2.8 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
| 0.0 | 0.2 | REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
| 0.0 | 0.9 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 0.8 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.0 | 0.7 | REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
| 0.0 | 0.6 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.0 | 1.8 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 1.9 | REACTOME ANTIGEN PROCESSING CROSS PRESENTATION | Genes involved in Antigen processing-Cross presentation |
| 0.0 | 1.5 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 0.7 | REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
| 0.0 | 1.7 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 1.3 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 0.4 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.0 | 0.8 | REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
| 0.0 | 1.4 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.0 | 1.4 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 1.5 | REACTOME L1CAM INTERACTIONS | Genes involved in L1CAM interactions |
| 0.0 | 0.8 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |