Project

Inflammatory response time course, HUVEC (Wada, 2009)

Navigation
Downloads

Results for HMGA1

Z-value: 1.58

Motif logo

Transcription factors associated with HMGA1

Gene Symbol Gene ID Gene Info
ENSG00000137309.20 HMGA1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMGA1hg38_v1_chr6_+_34236865_34236887-0.527.9e-03Click!

Activity profile of HMGA1 motif

Sorted Z-values of HMGA1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HMGA1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image
Promoter Score Transcript Gene Gene Info
chr9_-_41908681 16.74 ENST00000476961.5
contactin associated protein family member 3B
chr4_+_41538143 12.38 ENST00000503057.6
ENST00000511496.5
LIM and calponin homology domains 1
chr3_-_18438767 8.92 ENST00000454909.6
SATB homeobox 1
chr4_-_89835617 7.65 ENST00000611107.1
ENST00000345009.8
ENST00000505199.5
ENST00000502987.5
synuclein alpha
chr9_-_39288138 6.61 ENST00000297668.10
contactin associated protein family member 3
chr4_-_185775271 6.07 ENST00000430503.5
ENST00000319454.10
ENST00000450341.5
sorbin and SH3 domain containing 2
chr13_+_31945826 5.88 ENST00000647500.1
FRY microtubule binding protein
chr2_-_187448244 5.73 ENST00000392370.8
ENST00000410068.5
ENST00000447403.5
ENST00000410102.5
calcitonin receptor like receptor
chr13_+_102656933 5.53 ENST00000650757.1
tripeptidyl peptidase 2
chr3_+_194136138 5.14 ENST00000232424.4
hes family bHLH transcription factor 1
chr9_+_2159672 5.12 ENST00000634343.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr10_-_114684612 4.74 ENST00000533213.6
ENST00000369252.8
actin binding LIM protein 1
chr4_-_137532452 4.53 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
protocadherin 18
chr1_+_84164962 4.46 ENST00000614872.4
ENST00000394839.6
protein kinase cAMP-activated catalytic subunit beta
chr3_-_18424533 4.38 ENST00000417717.6
SATB homeobox 1
chr18_+_75210755 4.37 ENST00000322038.5
teashirt zinc finger homeobox 1
chr2_+_238138661 4.33 ENST00000409223.2
kelch like family member 30
chr1_+_84181630 4.30 ENST00000610457.1
protein kinase cAMP-activated catalytic subunit beta
chr5_+_62578810 4.28 ENST00000334994.6
ENST00000409534.1
leucine rich repeat containing 70
importin 11
chr10_-_114684457 4.14 ENST00000392955.7
actin binding LIM protein 1
chrX_-_19965142 4.11 ENST00000340625.3
BCLAF1 and THRAP3 family member 3
chr10_+_92834594 4.10 ENST00000371552.8
exocyst complex component 6
chr4_-_185775890 3.98 ENST00000437304.6
sorbin and SH3 domain containing 2
chr4_-_185956652 3.92 ENST00000355634.9
sorbin and SH3 domain containing 2
chr7_-_120858066 3.92 ENST00000222747.8
tetraspanin 12
chr10_+_92831153 3.85 ENST00000672817.1
exocyst complex component 6
chr1_+_60865259 3.65 ENST00000371191.5
nuclear factor I A
chr8_-_3409528 3.60 ENST00000335551.11
CUB and Sushi multiple domains 1
chr2_+_178320228 3.54 ENST00000315022.2
oxysterol binding protein like 6
chr18_+_75210789 3.37 ENST00000580243.3
teashirt zinc finger homeobox 1
chr10_+_35167516 3.35 ENST00000361599.8
cAMP responsive element modulator
chr9_-_42129125 3.31 ENST00000617422.4
ENST00000612828.4
ENST00000341990.8
ENST00000377561.7
ENST00000276974.7
contactin associated protein family member 3B
chr13_+_32031706 3.29 ENST00000542859.6
FRY microtubule binding protein
chr1_+_77918128 3.28 ENST00000342754.5
nexilin F-actin binding protein
chr12_+_8992029 3.17 ENST00000543895.1
killer cell lectin like receptor G1
chr17_-_69141878 3.13 ENST00000590645.1
ENST00000284425.7
ATP binding cassette subfamily A member 6
chr9_-_14307928 3.11 ENST00000637640.1
ENST00000493697.1
ENST00000636057.1
nuclear factor I B
chr4_-_158159657 3.08 ENST00000590648.5
golgi associated kinase 1B
chr6_+_36029082 2.97 ENST00000472333.1
mitogen-activated protein kinase 14
chr5_-_88731827 2.94 ENST00000627170.2
myocyte enhancer factor 2C
chr13_-_48413105 2.91 ENST00000620633.5
lysophosphatidic acid receptor 6
chr2_-_98663464 2.87 ENST00000414521.6
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
chr7_+_94394886 2.86 ENST00000297268.11
ENST00000620463.1
collagen type I alpha 2 chain
chr1_-_153094521 2.75 ENST00000368750.8
small proline rich protein 2E
chr12_+_78864768 2.75 ENST00000261205.9
ENST00000457153.6
synaptotagmin 1
chr9_+_87497222 2.60 ENST00000358077.9
death associated protein kinase 1
chr4_+_133149278 2.59 ENST00000264360.7
protocadherin 10
chr8_+_27633863 2.59 ENST00000337221.8
scavenger receptor class A member 3
chr22_-_28711931 2.56 ENST00000434810.5
ENST00000456369.5
checkpoint kinase 2
chr1_+_78004930 2.55 ENST00000370763.6
DnaJ heat shock protein family (Hsp40) member B4
chr7_-_120858303 2.55 ENST00000415871.5
ENST00000430985.1
tetraspanin 12
chr3_-_15798184 2.51 ENST00000624145.3
ankyrin repeat domain 28
chr12_+_12785652 2.48 ENST00000356591.5
apolipoprotein L domain containing 1
chr6_-_75363003 2.44 ENST00000370020.1
filamin A interacting protein 1
chr9_-_72953047 2.44 ENST00000297785.8
ENST00000376939.5
aldehyde dehydrogenase 1 family member A1
chrX_-_117973579 2.42 ENST00000371878.5
kelch like family member 13
chr4_+_143381939 2.39 ENST00000505913.5
GRB2 associated binding protein 1
chr5_-_88785493 2.38 ENST00000503554.4
myocyte enhancer factor 2C
chr12_+_32502114 2.37 ENST00000682739.1
ENST00000427716.7
ENST00000583694.2
FYVE, RhoGEF and PH domain containing 4
chr5_+_69415065 2.32 ENST00000647531.1
ENST00000645446.1
ENST00000325631.10
ENST00000454295.6
MARVEL domain containing 2
chr2_+_42494547 2.31 ENST00000405592.5
metastasis associated 1 family member 3
chr12_+_19205294 2.30 ENST00000424268.5
pleckstrin homology domain containing A5
chr8_-_17676484 2.24 ENST00000634613.1
ENST00000519066.5
microtubule associated scaffold protein 1
chr7_-_122098831 2.22 ENST00000681213.1
ENST00000679419.1
aminoadipate-semialdehyde synthase
chr9_+_2159850 2.21 ENST00000416751.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_+_162318884 2.19 ENST00000446271.5
ENST00000429691.6
grancalcin
chr13_-_44437214 2.17 ENST00000622051.1
TSC22 domain family member 1
chr2_-_69643152 2.15 ENST00000606389.7
AP2 associated kinase 1
chr7_+_150567347 2.13 ENST00000461940.5
GTPase, IMAP family member 4
chr2_+_190927649 2.11 ENST00000409428.5
ENST00000409215.5
glutaminase
chr8_-_17697654 2.10 ENST00000297488.10
microtubule associated scaffold protein 1
chrX_-_117973717 2.08 ENST00000262820.7
kelch like family member 13
chr4_-_69860138 2.08 ENST00000226444.4
sulfotransferase family 1E member 1
chr10_+_35195124 2.05 ENST00000487763.5
ENST00000473940.5
ENST00000488328.5
ENST00000356917.9
cAMP responsive element modulator
chr3_-_185821092 2.05 ENST00000421047.3
insulin like growth factor 2 mRNA binding protein 2
chr7_+_150567382 2.03 ENST00000255945.4
ENST00000479232.1
GTPase, IMAP family member 4
chr17_-_445939 2.02 ENST00000329099.4
refilin B
chrX_-_10677720 2.01 ENST00000453318.6
midline 1
chr7_+_93921720 2.00 ENST00000248564.6
G protein subunit gamma 11
chr14_-_91946989 2.00 ENST00000556154.5
fibulin 5
chr4_+_122339221 2.00 ENST00000442707.1
KIAA1109
chr2_+_66435116 1.98 ENST00000272369.14
ENST00000560281.6
Meis homeobox 1
chr16_-_3372666 1.98 ENST00000399974.5
MT-RNR2 like 4
chr3_+_132597260 1.91 ENST00000249887.3
atypical chemokine receptor 4
chr20_-_61998132 1.90 ENST00000474089.5
TATA-box binding protein associated factor 4
chr7_+_92057602 1.89 ENST00000491695.2
A-kinase anchoring protein 9
chr9_-_123184233 1.89 ENST00000447404.6
spermatid perinuclear RNA binding protein
chr15_+_57219411 1.88 ENST00000543579.5
ENST00000537840.5
ENST00000343827.7
transcription factor 12
chr8_+_73991345 1.88 ENST00000284818.7
ENST00000518893.1
lymphocyte antigen 96
chr2_-_221572272 1.85 ENST00000409854.5
ENST00000443796.5
ENST00000281821.7
EPH receptor A4
chr1_+_65264694 1.84 ENST00000263441.11
ENST00000395325.7
DnaJ heat shock protein family (Hsp40) member C6
chr11_-_66347560 1.82 ENST00000311181.5
beta-1,4-glucuronyltransferase 1
chr2_-_69643615 1.81 ENST00000409068.5
AP2 associated kinase 1
chr4_-_109801978 1.81 ENST00000510800.1
ENST00000512148.5
ENST00000394634.7
ENST00000394635.8
ENST00000645635.1
complement factor I
novel protein
chr18_-_55510753 1.80 ENST00000543082.5
transcription factor 4
chr6_-_52994248 1.80 ENST00000457564.1
ENST00000370960.5
glutathione S-transferase alpha 4
chr2_+_108588453 1.79 ENST00000393310.5
LIM zinc finger domain containing 1
chr8_+_95024977 1.77 ENST00000396124.9
NADH:ubiquinone oxidoreductase complex assembly factor 6
chr13_-_67230377 1.75 ENST00000544246.5
ENST00000377861.4
protocadherin 9
chr6_+_30888672 1.75 ENST00000446312.5
discoidin domain receptor tyrosine kinase 1
chr2_+_108588286 1.74 ENST00000332345.10
LIM zinc finger domain containing 1
chr14_-_20802402 1.71 ENST00000412779.2
ribonuclease A family member 1, pancreatic
chr5_-_88877967 1.68 ENST00000508610.5
ENST00000636294.1
myocyte enhancer factor 2C
chr13_-_44474296 1.67 ENST00000611198.4
TSC22 domain family member 1
chr2_-_182242031 1.66 ENST00000358139.6
phosphodiesterase 1A
chr18_-_55588535 1.65 ENST00000566286.5
ENST00000566279.5
ENST00000626595.2
ENST00000564999.5
ENST00000616053.4
ENST00000356073.8
transcription factor 4
chr7_+_116222804 1.64 ENST00000393481.6
testin LIM domain protein
chrX_-_77634229 1.63 ENST00000675732.1
ATRX chromatin remodeler
chr22_-_28306645 1.63 ENST00000612946.4
tetratricopeptide repeat domain 28
chr12_+_20810698 1.63 ENST00000540853.5
ENST00000381545.8
solute carrier organic anion transporter family member 1B3
chr15_-_99249523 1.62 ENST00000560235.1
ENST00000394132.7
ENST00000560860.5
ENST00000558078.5
ENST00000560772.5
tetratricopeptide repeat domain 23
chr2_+_1414382 1.62 ENST00000423320.5
ENST00000346956.7
ENST00000382198.5
thyroid peroxidase
chrX_-_20218941 1.62 ENST00000457145.6
ribosomal protein S6 kinase A3
chr1_+_179882040 1.61 ENST00000528443.6
torsin 1A interacting protein 1
chr22_-_28712136 1.60 ENST00000464581.6
checkpoint kinase 2
chr12_+_59596010 1.56 ENST00000547379.6
ENST00000552432.5
solute carrier family 16 member 7
chrX_-_10576901 1.55 ENST00000380779.5
midline 1
chr1_+_196652022 1.54 ENST00000367429.9
ENST00000630130.2
ENST00000359637.2
complement factor H
chr5_+_141192330 1.53 ENST00000239446.6
protocadherin beta 10
chr5_+_141223332 1.52 ENST00000239449.7
ENST00000624896.1
ENST00000624396.1
protocadherin beta 14
novel protein
chr15_+_47717344 1.49 ENST00000558816.5
ENST00000536845.7
semaphorin 6D
chr8_+_27633884 1.49 ENST00000301904.4
scavenger receptor class A member 3
chr17_+_7857987 1.48 ENST00000332439.5
cytochrome b5 domain containing 1
chr12_+_101594849 1.47 ENST00000547405.5
ENST00000452455.6
ENST00000392934.7
ENST00000547509.5
ENST00000361685.6
ENST00000549145.5
ENST00000361466.7
ENST00000553190.5
ENST00000545503.6
ENST00000536007.5
ENST00000541119.5
ENST00000551300.5
ENST00000550270.1
myosin binding protein C1
chr17_-_65826445 1.47 ENST00000317442.12
centrosomal protein 112
chr4_-_88823306 1.46 ENST00000395002.6
family with sequence similarity 13 member A
chr12_-_46372763 1.44 ENST00000256689.10
solute carrier family 38 member 2
chr4_-_151226427 1.43 ENST00000304527.8
ENST00000409598.8
SH3 domain containing 19
chr13_-_44436801 1.43 ENST00000261489.6
TSC22 domain family member 1
chr7_-_92134737 1.40 ENST00000450723.5
cytochrome P450 family 51 subfamily A member 1
chr18_-_36829154 1.40 ENST00000614939.4
ENST00000610723.4
tubulin polyglutamylase complex subunit 2
chr4_+_89894846 1.39 ENST00000264790.7
multimerin 1
chr3_+_124584625 1.37 ENST00000291478.9
ENST00000682363.1
ENST00000454902.1
kalirin RhoGEF kinase
chr12_+_59689337 1.33 ENST00000261187.8
solute carrier family 16 member 7
chr5_-_88823763 1.32 ENST00000635898.1
ENST00000626391.2
ENST00000628656.2
myocyte enhancer factor 2C
chr2_+_188974364 1.31 ENST00000304636.9
ENST00000317840.9
collagen type III alpha 1 chain
chr6_-_132798587 1.31 ENST00000275227.9
solute carrier family 18 member B1
chr12_+_56267674 1.31 ENST00000546544.5
ENST00000553234.1
coenzyme Q10A
chr1_+_179882275 1.30 ENST00000606911.7
ENST00000271583.7
torsin 1A interacting protein 1
chr9_+_73151833 1.30 ENST00000456643.5
ENST00000257497.11
ENST00000415424.5
annexin A1
chr3_-_197573323 1.30 ENST00000358186.6
ENST00000431056.5
3-hydroxybutyrate dehydrogenase 1
chr9_-_21202205 1.29 ENST00000239347.3
interferon alpha 7
chr5_-_111758061 1.27 ENST00000509979.5
ENST00000513100.5
ENST00000508161.5
ENST00000455559.6
neuronal regeneration related protein
chr14_-_89619118 1.26 ENST00000345097.8
ENST00000555855.5
ENST00000555353.5
forkhead box N3
chr18_-_55321640 1.25 ENST00000637169.2
transcription factor 4
chr5_+_140834230 1.25 ENST00000356878.5
ENST00000525929.2
protocadherin alpha 7
chr1_-_179143044 1.24 ENST00000504405.5
ENST00000512653.5
ENST00000344730.7
ABL proto-oncogene 2, non-receptor tyrosine kinase
chr8_+_11809135 1.24 ENST00000528643.5
ENST00000525777.5
farnesyl-diphosphate farnesyltransferase 1
chr14_-_75069478 1.24 ENST00000555463.1
acylphosphatase 1
chr13_+_75804221 1.22 ENST00000489941.6
ENST00000525373.5
LIM domain 7
chr12_-_12338674 1.21 ENST00000545735.1
MANSC domain containing 1
chr1_+_207770322 1.21 ENST00000462968.2
CD46 molecule
chr7_+_107583919 1.21 ENST00000491150.5
B cell receptor associated protein 29
chr11_+_9575496 1.21 ENST00000681684.1
WEE1 G2 checkpoint kinase
chr12_-_70754631 1.21 ENST00000440835.6
ENST00000549308.5
ENST00000550661.1
ENST00000378778.5
protein tyrosine phosphatase receptor type R
chr1_+_51617079 1.20 ENST00000447887.5
ENST00000428468.6
ENST00000453295.5
oxysterol binding protein like 9
chr6_-_116254063 1.18 ENST00000420283.3
TSPY like 4
chr2_+_172735912 1.18 ENST00000409036.5
Rap guanine nucleotide exchange factor 4
chr4_+_89901979 1.18 ENST00000508372.1
multimerin 1
chr17_-_69060906 1.17 ENST00000495634.5
ENST00000453985.6
ENST00000340001.9
ENST00000585714.1
ATP binding cassette subfamily A member 9
chr13_-_67230313 1.17 ENST00000377865.7
protocadherin 9
chr7_+_117014881 1.14 ENST00000422922.5
ENST00000432298.5
suppression of tumorigenicity 7
chr10_-_125158704 1.14 ENST00000531469.5
C-terminal binding protein 2
chr20_+_11917859 1.13 ENST00000618296.4
ENST00000378226.7
BTB domain containing 3
chr14_-_21537206 1.13 ENST00000614342.1
spalt like transcription factor 2
chr7_+_116862552 1.13 ENST00000361183.8
ENST00000639546.1
ENST00000490693.5
capping actin protein of muscle Z-line subunit alpha 2
chr14_-_20305932 1.11 ENST00000258821.8
ENST00000553828.1
tetratricopeptide repeat domain 5
chr4_-_25863537 1.11 ENST00000502949.5
ENST00000264868.9
ENST00000513691.1
ENST00000514872.1
SEL1L family member 3
chr14_-_34713759 1.11 ENST00000673315.1
cofilin 2
chr6_-_69699124 1.11 ENST00000651675.1
LMBR1 domain containing 1
chr22_+_40177917 1.10 ENST00000454349.7
ENST00000335727.13
trinucleotide repeat containing adaptor 6B
chr3_+_148865288 1.10 ENST00000296046.4
carboxypeptidase A3
chr1_+_145964675 1.10 ENST00000369314.2
ENST00000369313.7
RNA polymerase III subunit GL
chr5_+_119476530 1.09 ENST00000645099.1
ENST00000513628.5
hydroxysteroid 17-beta dehydrogenase 4
chr6_+_152697888 1.09 ENST00000367245.5
ENST00000529453.1
MYC target 1
chrX_+_37780049 1.09 ENST00000378588.5
cytochrome b-245 beta chain
chr11_-_104898670 1.08 ENST00000422698.6
caspase 12 (gene/pseudogene)
chr10_+_119819244 1.08 ENST00000637174.1
inositol polyphosphate-5-phosphatase F
chr1_+_163068775 1.06 ENST00000421743.6
regulator of G protein signaling 4
chr6_+_152697934 1.05 ENST00000532295.1
MYC target 1
chr9_-_110337808 1.05 ENST00000374510.8
ENST00000374507.4
ENST00000423740.7
ENST00000374511.7
thioredoxin domain containing 8
chr8_-_81483226 1.05 ENST00000256104.5
fatty acid binding protein 4
chr17_+_3475959 1.04 ENST00000263080.3
aspartoacylase
chr9_+_72628020 1.03 ENST00000646619.1
transmembrane channel like 1
chr3_-_123980727 1.01 ENST00000620893.4
rhophilin associated tail protein 1
chr7_+_832470 1.01 ENST00000401592.6
Sad1 and UNC84 domain containing 1
chr3_+_148791058 1.01 ENST00000491148.5
carboxypeptidase B1
chr12_+_12725897 1.00 ENST00000326765.10
apolipoprotein L domain containing 1
chr3_-_149377637 1.00 ENST00000305366.8
transmembrane 4 L six family member 1
chrX_-_101617921 0.99 ENST00000361910.9
ENST00000538627.5
ENST00000539247.5
armadillo repeat containing X-linked 6
chr12_-_102197827 0.99 ENST00000329406.5
pro-melanin concentrating hormone
chr10_-_45594760 0.98 ENST00000319836.7
membrane associated ring-CH-type finger 8
chr2_+_209580024 0.98 ENST00000392194.5
microtubule associated protein 2
chrX_-_81201886 0.98 ENST00000451455.1
ENST00000358130.7
ENST00000436386.5
high mobility group nucleosome binding domain 5
chr11_+_58622659 0.98 ENST00000361987.6
ciliary neurotrophic factor
chrX_+_10158448 0.97 ENST00000380829.5
ENST00000421085.7
ENST00000674669.1
ENST00000454850.1
chloride voltage-gated channel 4
chr7_-_56051544 0.97 ENST00000395471.7
phosphoserine phosphatase
chr2_+_172735838 0.97 ENST00000397081.8
Rap guanine nucleotide exchange factor 4
chr3_-_69080350 0.97 ENST00000630585.1
ENST00000361055.9
ENST00000415609.6
ENST00000349511.8
ubiquitin like modifier activating enzyme 3
chr2_-_201739205 0.96 ENST00000681558.1
ENST00000681495.1
alsin Rho guanine nucleotide exchange factor ALS2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 9.2 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
1.7 5.1 GO:0042668 trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164) negative regulation of pro-B cell differentiation(GO:2000974)
1.4 4.2 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
1.3 7.7 GO:0060023 soft palate development(GO:0060023)
1.3 7.7 GO:1903284 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
1.3 8.8 GO:0097338 response to clozapine(GO:0097338)
1.0 8.3 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
1.0 1.0 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.9 2.8 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.8 13.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.7 2.2 GO:0019878 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.7 2.1 GO:0006711 estrogen catabolic process(GO:0006711)
0.7 2.0 GO:0061182 negative regulation of chondrocyte development(GO:0061182)
0.6 1.9 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.5 1.6 GO:0034183 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.5 3.0 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.4 5.7 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.4 1.3 GO:0036292 DNA rewinding(GO:0036292)
0.4 2.4 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.4 1.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.4 1.1 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.4 1.1 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.4 2.9 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.4 2.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.3 1.0 GO:0006533 aspartate catabolic process(GO:0006533)
0.3 13.2 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.3 1.0 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.3 1.8 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.3 0.9 GO:0097274 urea homeostasis(GO:0097274)
0.3 2.9 GO:0071763 nuclear membrane organization(GO:0071763)
0.3 3.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.3 1.1 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.3 1.9 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.3 0.8 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.3 0.8 GO:0014813 skeletal muscle satellite cell commitment(GO:0014813)
0.3 0.8 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.3 4.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.2 0.7 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.2 1.0 GO:0007113 endomitotic cell cycle(GO:0007113)
0.2 1.0 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.2 3.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.2 0.7 GO:0071206 establishment of protein localization to juxtaparanode region of axon(GO:0071206)
0.2 1.1 GO:0038016 insulin receptor internalization(GO:0038016)
0.2 1.3 GO:0046952 ketone body catabolic process(GO:0046952)
0.2 0.9 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.2 4.1 GO:0009650 UV protection(GO:0009650)
0.2 0.6 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.2 0.8 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 1.2 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.2 1.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2 1.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.2 2.0 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 0.8 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.2 0.6 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.2 1.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 3.0 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.2 2.4 GO:0043589 skin morphogenesis(GO:0043589)
0.2 0.8 GO:0061760 antifungal innate immune response(GO:0061760)
0.2 1.8 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.2 0.8 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.4 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 0.4 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.6 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.1 5.9 GO:0010842 retina layer formation(GO:0010842)
0.1 1.6 GO:0090292 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 1.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 2.0 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 1.4 GO:0032328 alanine transport(GO:0032328)
0.1 0.9 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1 0.4 GO:0060931 sinoatrial node cell development(GO:0060931)
0.1 0.7 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.1 0.8 GO:0071461 cellular response to redox state(GO:0071461)
0.1 1.4 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 0.5 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.7 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.1 1.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 3.7 GO:0072189 ureter development(GO:0072189)
0.1 2.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 1.1 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1 0.4 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.1 0.6 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.5 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.5 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.1 1.1 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.1 0.8 GO:0016139 glycoside catabolic process(GO:0016139)
0.1 0.5 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.1 1.5 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.8 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 1.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.5 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.6 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.7 GO:0051552 flavone metabolic process(GO:0051552)
0.1 0.6 GO:0051697 protein delipidation(GO:0051697)
0.1 1.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 1.0 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.5 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 7.3 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.5 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1 1.3 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 5.4 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 0.6 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 4.8 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 1.1 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.1 1.9 GO:0060044 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.1 3.1 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 2.7 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 2.6 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.5 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1 2.5 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.4 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.6 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.1 0.6 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.1 3.5 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.1 0.7 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.1 0.7 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 1.5 GO:0006012 galactose metabolic process(GO:0006012)
0.1 1.0 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 1.6 GO:0006590 thyroid hormone generation(GO:0006590)
0.1 14.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.3 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.1 2.9 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 8.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 1.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 0.5 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.1 0.3 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 2.2 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.1 1.1 GO:0072672 neutrophil extravasation(GO:0072672)
0.1 0.6 GO:0034465 response to carbon monoxide(GO:0034465)
0.1 1.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.2 GO:0007538 primary sex determination(GO:0007538)
0.1 1.1 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.1 1.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.6 GO:0001956 positive regulation of neurotransmitter secretion(GO:0001956)
0.1 1.8 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1 1.2 GO:0060347 heart trabecula formation(GO:0060347)
0.1 0.3 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.1 1.1 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.2 GO:0070101 positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.1 1.1 GO:0097264 self proteolysis(GO:0097264)
0.1 1.0 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 1.3 GO:0002003 angiotensin maturation(GO:0002003)
0.1 0.3 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 1.9 GO:0002323 natural killer cell activation involved in immune response(GO:0002323)
0.1 0.8 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.4 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.1 1.6 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.1 0.5 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.1 0.3 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.1 0.6 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.6 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.6 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 1.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 9.4 GO:0007286 spermatid development(GO:0007286)
0.0 0.6 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.5 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 1.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 1.5 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.2 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.1 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.0 0.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 1.9 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.7 GO:0075522 IRES-dependent translational initiation(GO:0002192) IRES-dependent viral translational initiation(GO:0075522)
0.0 0.3 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.4 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.5 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 1.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 1.9 GO:0018149 peptide cross-linking(GO:0018149)
0.0 1.1 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.0 1.0 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.1 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.1 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.0 0.6 GO:0097435 fibril organization(GO:0097435)
0.0 2.4 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.6 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 1.1 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.5 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.3 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 2.1 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.5 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.8 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.0 1.5 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 1.2 GO:0051353 positive regulation of oxidoreductase activity(GO:0051353)
0.0 7.2 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.9 GO:0072663 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.1 GO:0006169 adenosine salvage(GO:0006169) dATP biosynthetic process(GO:0006175)
0.0 0.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.4 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.3 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 5.0 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 2.0 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.5 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.8 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.1 GO:0039513 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 7.2 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 1.0 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 1.8 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 1.0 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 1.1 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.3 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 0.8 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.0 0.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.3 GO:1901798 positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.3 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.3 GO:0035886 vascular smooth muscle cell differentiation(GO:0035886)
0.0 0.2 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 1.0 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 1.1 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.7 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 1.1 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.0 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.1 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.3 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 1.6 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.2 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 1.0 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.5 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.7 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 1.2 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.2 GO:0090312 positive regulation of protein deacetylation(GO:0090312)
0.0 0.2 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.9 GO:0007605 sensory perception of sound(GO:0007605)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.8 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.5 1.9 GO:0044307 dendritic branch(GO:0044307)
0.4 1.6 GO:0031933 telomeric heterochromatin(GO:0031933)
0.4 8.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 1.0 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.3 12.6 GO:0005720 nuclear heterochromatin(GO:0005720)
0.3 7.5 GO:0000145 exocyst(GO:0000145)
0.3 3.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 2.3 GO:0061689 tricellular tight junction(GO:0061689)
0.2 2.0 GO:0071953 elastic fiber(GO:0071953)
0.2 1.9 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 1.2 GO:0031417 NatC complex(GO:0031417)
0.2 7.3 GO:0071564 npBAF complex(GO:0071564)
0.2 1.2 GO:0002079 inner acrosomal membrane(GO:0002079)
0.2 1.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.2 1.1 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.2 7.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 3.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 2.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.4 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 1.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.9 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 3.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.8 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 1.9 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 8.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 3.2 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 1.6 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 1.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 10.2 GO:0032432 actin filament bundle(GO:0032432)
0.1 2.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.3 GO:0071920 cleavage body(GO:0071920)
0.1 1.2 GO:0097433 dense body(GO:0097433)
0.1 0.3 GO:0005602 complement component C1 complex(GO:0005602)
0.1 1.1 GO:0097470 ribbon synapse(GO:0097470)
0.1 0.3 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 0.8 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.7 GO:0000439 core TFIIH complex(GO:0000439)
0.1 0.6 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 1.3 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 14.6 GO:0030018 Z disc(GO:0030018)
0.1 1.0 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.2 GO:0097679 other organism cytoplasm(GO:0097679)
0.1 12.9 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.5 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 4.4 GO:0043195 terminal bouton(GO:0043195)
0.0 4.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.5 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.0 1.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 2.2 GO:0001533 cornified envelope(GO:0001533)
0.0 0.7 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 2.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 2.9 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 2.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.6 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.6 GO:0036038 MKS complex(GO:0036038)
0.0 2.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.5 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 0.4 GO:0071439 clathrin complex(GO:0071439)
0.0 4.5 GO:0032993 protein-DNA complex(GO:0032993)
0.0 3.8 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 3.3 GO:0001650 fibrillar center(GO:0001650)
0.0 7.5 GO:0005819 spindle(GO:0005819)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.0 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.9 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.7 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 1.7 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.7 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.8 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.3 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)
0.0 6.1 GO:0005925 focal adhesion(GO:0005925)
0.0 1.7 GO:0031902 late endosome membrane(GO:0031902)
0.0 2.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.7 GO:0004948 calcitonin receptor activity(GO:0004948)
1.3 7.7 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
1.1 5.5 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
1.0 2.9 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.5 8.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.5 1.6 GO:0015616 DNA translocase activity(GO:0015616)
0.5 1.5 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.5 14.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.5 2.8 GO:0030348 syntaxin-3 binding(GO:0030348)
0.4 8.3 GO:0003680 AT DNA binding(GO:0003680)
0.4 1.3 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.4 2.4 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.4 1.1 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.4 1.1 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.4 2.1 GO:0004359 glutaminase activity(GO:0004359)
0.3 2.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.3 1.6 GO:0004447 iodide peroxidase activity(GO:0004447)
0.3 5.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.3 0.9 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.3 1.8 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.3 1.8 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.3 1.7 GO:0004522 ribonuclease A activity(GO:0004522)
0.3 4.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.3 1.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.3 3.0 GO:0051525 NFAT protein binding(GO:0051525)
0.3 2.9 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.3 1.3 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.3 0.8 GO:0070538 oleic acid binding(GO:0070538)
0.2 6.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 1.9 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.2 4.7 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 1.2 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.2 1.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.2 4.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 1.0 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.2 2.1 GO:0042731 PH domain binding(GO:0042731)
0.2 2.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 0.7 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.2 1.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 1.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 5.5 GO:0001671 ATPase activator activity(GO:0001671)
0.1 1.0 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 1.1 GO:0015235 cobalamin transporter activity(GO:0015235)
0.1 1.1 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 2.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 1.3 GO:0048039 ubiquinone binding(GO:0048039)
0.1 1.0 GO:0004046 aminoacylase activity(GO:0004046)
0.1 2.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.6 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 1.9 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 4.7 GO:0015248 sterol transporter activity(GO:0015248)
0.1 3.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.0 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 0.8 GO:0019763 immunoglobulin receptor activity(GO:0019763) IgE binding(GO:0019863)
0.1 7.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 1.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 0.7 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 1.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.7 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.7 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 0.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 7.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.8 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.8 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.5 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 1.5 GO:0035497 cAMP response element binding(GO:0035497)
0.1 1.0 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.3 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.3 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1 0.2 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.5 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 1.9 GO:0031005 filamin binding(GO:0031005)
0.1 0.5 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 1.9 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.1 1.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 24.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 2.2 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 2.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.6 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 1.6 GO:0002162 dystroglycan binding(GO:0002162)
0.1 1.6 GO:0005521 lamin binding(GO:0005521)
0.1 0.5 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 2.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.5 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 1.3 GO:0031432 titin binding(GO:0031432)
0.1 0.6 GO:0051425 PTB domain binding(GO:0051425)
0.1 2.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.6 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 1.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.5 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.2 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.0 0.1 GO:0052815 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
0.0 2.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.9 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.3 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 1.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.6 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.2 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.0 1.0 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.8 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 2.7 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.7 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.3 GO:0089720 caspase binding(GO:0089720)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 1.4 GO:0032451 demethylase activity(GO:0032451)
0.0 2.0 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.9 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.8 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0004001 adenosine kinase activity(GO:0004001)
0.0 0.8 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252) acid-sensing ion channel activity(GO:0044736)
0.0 2.7 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 17.2 GO:0003779 actin binding(GO:0003779)
0.0 0.7 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.6 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 2.3 GO:0005518 collagen binding(GO:0005518)
0.0 0.4 GO:0008494 translation activator activity(GO:0008494)
0.0 0.7 GO:0001848 complement binding(GO:0001848)
0.0 0.9 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.4 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 16.1 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.7 GO:0030332 cyclin binding(GO:0030332)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.0 GO:1901476 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0035877 death effector domain binding(GO:0035877) cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 1.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.8 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.8 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 1.0 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 2.0 GO:0005516 calmodulin binding(GO:0005516)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 12.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.2 8.8 PID IL3 PATHWAY IL3-mediated signaling events
0.2 8.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 2.9 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 7.1 PID INSULIN PATHWAY Insulin Pathway
0.1 14.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 4.2 PID ATM PATHWAY ATM pathway
0.1 1.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 2.4 PID EPO PATHWAY EPO signaling pathway
0.1 7.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 1.5 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 4.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 4.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 4.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 5.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.9 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 1.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 3.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 0.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 1.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 3.3 PID AURORA B PATHWAY Aurora B signaling
0.1 2.4 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 1.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.9 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.3 PID IGF1 PATHWAY IGF1 pathway
0.0 1.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.1 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.1 PID P53 REGULATION PATHWAY p53 pathway
0.0 2.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.5 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.6 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.4 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.4 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.6 ST FAS SIGNALING PATHWAY Fas Signaling Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 10.6 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.3 11.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.3 5.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.3 12.9 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.3 7.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.2 6.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.2 5.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 2.9 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 8.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.2 2.6 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 3.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 2.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 3.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 2.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.9 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 10.4 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 3.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 6.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 2.0 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 4.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.9 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 0.9 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 0.5 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 2.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 2.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 4.7 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 2.2 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 1.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 2.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.8 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 0.9 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.9 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.9 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 5.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.1 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 3.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.5 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 1.1 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 1.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 2.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 2.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 1.1 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 3.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)