Inflammatory response time course, HUVEC (Wada, 2009)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
HMX1 Links Ensembl NCBI GeneCards UniProt	ENSG00000215612.8	HMX1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
HMX1	hg38_v1_chr4_-_8871817_8871857	-0.19	3.7e-01	Click!

View svg image
View png image

Promoter	Score	Transcript	Gene	Gene Info
chr1_-_58577244 Show fit	2.79	ENST00000371225.4	TACSTD2 Links Ensembl NCBI GeneCards UniProt Show fit	tumor associated calcium signal transducer 2
chr5_-_81751022 Show fit	2.76	ENST00000509013.2 ENST00000505980.5 ENST00000509053.5	SSBP2 Links Ensembl NCBI GeneCards UniProt Show fit	single stranded DNA binding protein 2
chr4_-_185812209 Show fit	2.75	ENST00000393523.6 ENST00000393528.7 ENST00000449407.6	SORBS2 Links Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 2
chr5_-_81751085 Show fit	2.38	ENST00000515395.5	SSBP2 Links Ensembl NCBI GeneCards UniProt Show fit	single stranded DNA binding protein 2
chr12_+_53046969 Show fit	2.27	ENST00000379902.7	TNS2 Links Ensembl NCBI GeneCards UniProt Show fit	tensin 2
chr2_+_69013170 Show fit	2.13	ENST00000303714.9	ANTXR1 Links Ensembl NCBI GeneCards UniProt Show fit	ANTXR cell adhesion molecule 1
chr14_+_63204859 Show fit	2.06	ENST00000555125.1	RHOJ Links Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member J
chr12_+_57089094 Show fit	2.01	ENST00000342556.6 ENST00000300131.8	NAB2 Links Ensembl NCBI GeneCards UniProt Show fit	NGFI-A binding protein 2
chr6_-_13486137 Show fit	1.94	ENST00000612338.4	GFOD1 Links Ensembl NCBI GeneCards UniProt Show fit	glucose-fructose oxidoreductase domain containing 1
chr14_-_105168753 Show fit	1.81	ENST00000331782.8 ENST00000347004.2	JAG2 Links Ensembl NCBI GeneCards UniProt Show fit	jagged canonical Notch ligand 2
chr14_+_63204436 Show fit	1.81	ENST00000316754.8	RHOJ Links Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member J
chr7_-_132576493 Show fit	1.76	ENST00000321063.8	PLXNA4 Links Ensembl NCBI GeneCards UniProt Show fit	plexin A4
chr1_-_32702736 Show fit	1.72	ENST00000373484.4 ENST00000409190.8	SYNC Links Ensembl NCBI GeneCards UniProt Show fit	syncoilin, intermediate filament protein
chr9_-_10612966 Show fit	1.31	ENST00000381196.9	PTPRD Links Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase receptor type D
chr17_-_8630749 Show fit	1.29	ENST00000379980.8 ENST00000269243.8	MYH10 Links Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 10
chr19_+_1407731 Show fit	1.28	ENST00000592453.2	DAZAP1 Links Ensembl NCBI GeneCards UniProt Show fit	DAZ associated protein 1
chr17_-_8630713 Show fit	1.25	ENST00000411957.1 ENST00000360416.8	MYH10 Links Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 10
chr11_+_59755427 Show fit	1.25	ENST00000529177.5	STX3 Links Ensembl NCBI GeneCards UniProt Show fit	syntaxin 3
chr6_+_85450033 Show fit	1.24	ENST00000257770.8 ENST00000369646.7	NT5E Links Ensembl NCBI GeneCards UniProt Show fit	5'-nucleotidase ecto
chr2_-_219571241 Show fit	1.24	ENST00000373876.5 ENST00000603926.5 ENST00000373873.8 ENST00000289656.3	OBSL1 Links Ensembl NCBI GeneCards UniProt Show fit	obscurin like cytoskeletal adaptor 1
chr9_-_127854636 Show fit	1.20	ENST00000344849.4 ENST00000373203.9	ENG Links Ensembl NCBI GeneCards UniProt Show fit	endoglin
chr19_-_14206168 Show fit	1.12	ENST00000361434.7 ENST00000340736.10	ADGRL1 Links Ensembl NCBI GeneCards UniProt Show fit	adhesion G protein-coupled receptor L1
chr1_-_46132650 Show fit	1.10	ENST00000372006.5 ENST00000425892.2 ENST00000420542.5	PIK3R3 Links Ensembl NCBI GeneCards UniProt Show fit	phosphoinositide-3-kinase regulatory subunit 3
chr5_+_139648338 Show fit	1.10	ENST00000302517.8	CXXC5 Links Ensembl NCBI GeneCards UniProt Show fit	CXXC finger protein 5
chr18_-_48409292 Show fit	1.10	ENST00000589194.5 ENST00000591279.5 ENST00000590855.5 ENST00000587107.5 ENST00000588970.5 ENST00000586525.5 ENST00000592387.5 ENST00000590800.6	ZBTB7C Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 7C
chr11_+_849816 Show fit	1.09	ENST00000527644.1	TSPAN4 Links Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 4
chr3_+_58008350 Show fit	1.07	ENST00000490882.5 ENST00000358537.7 ENST00000429972.6 ENST00000682871.1 ENST00000295956.9	FLNB Links Ensembl NCBI GeneCards UniProt Show fit	filamin B
chr11_+_59755365 Show fit	1.07	ENST00000337979.9	STX3 Links Ensembl NCBI GeneCards UniProt Show fit	syntaxin 3
chr12_-_48865863 Show fit	1.06	ENST00000309739.6	RND1 Links Ensembl NCBI GeneCards UniProt Show fit	Rho family GTPase 1
chr9_+_112750722 Show fit	1.06	ENST00000374232.8	SNX30 Links Ensembl NCBI GeneCards UniProt Show fit	sorting nexin family member 30
chr6_-_2245563 Show fit	1.05	ENST00000380815.5	GMDS Links Ensembl NCBI GeneCards UniProt Show fit	GDP-mannose 4,6-dehydratase
chr11_+_59755398 Show fit	1.01	ENST00000633708.1	STX3 Links Ensembl NCBI GeneCards UniProt Show fit	syntaxin 3
chr15_-_89655428 Show fit	1.00	ENST00000394412.8	KIF7 Links Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 7
chr17_-_64020544 Show fit	0.96	ENST00000583366.5	ICAM2 Links Ensembl NCBI GeneCards UniProt Show fit	intercellular adhesion molecule 2
chr1_-_46132616 Show fit	0.94	ENST00000423209.5 ENST00000262741.10	PIK3R3 Links Ensembl NCBI GeneCards UniProt Show fit	phosphoinositide-3-kinase regulatory subunit 3
chr7_+_130492066 Show fit	0.93	ENST00000223215.10 ENST00000437945.6	MEST Links Ensembl NCBI GeneCards UniProt Show fit	mesoderm specific transcript
chr7_-_156892987 Show fit	0.91	ENST00000415428.5	LMBR1 Links Ensembl NCBI GeneCards UniProt Show fit	limb development membrane protein 1
chr9_+_79571767 Show fit	0.88	ENST00000376544.7	TLE4 Links Ensembl NCBI GeneCards UniProt Show fit	TLE family member 4, transcriptional corepressor
chr2_+_61065863 Show fit	0.87	ENST00000402291.6	KIAA1841 Links Ensembl NCBI GeneCards UniProt Show fit	KIAA1841
chr11_-_19240936 Show fit	0.85	ENST00000250024.9	E2F8 Links Ensembl NCBI GeneCards UniProt Show fit	E2F transcription factor 8
chr12_+_32399517 Show fit	0.85	ENST00000534526.7	FGD4 Links Ensembl NCBI GeneCards UniProt Show fit	FYVE, RhoGEF and PH domain containing 4
chr17_-_64020566 Show fit	0.84	ENST00000578313.5 ENST00000584084.1 ENST00000579687.5 ENST00000578379.5 ENST00000578892.5 ENST00000579788.6 ENST00000412356.5 ENST00000418105.5	ICAM2 Links Ensembl NCBI GeneCards UniProt Show fit	intercellular adhesion molecule 2
chr3_+_50155024 Show fit	0.84	ENST00000414301.5 ENST00000450338.5 ENST00000413852.5	SEMA3F Links Ensembl NCBI GeneCards UniProt Show fit	semaphorin 3F
chr9_+_79571956 Show fit	0.82	ENST00000376552.8	TLE4 Links Ensembl NCBI GeneCards UniProt Show fit	TLE family member 4, transcriptional corepressor
chr1_-_26960369 Show fit	0.77	ENST00000616918.1	KDF1 Links Ensembl NCBI GeneCards UniProt Show fit	keratinocyte differentiation factor 1
chr1_-_26960413 Show fit	0.76	ENST00000320567.6	KDF1 Links Ensembl NCBI GeneCards UniProt Show fit	keratinocyte differentiation factor 1
chr22_+_29306582 Show fit	0.76	ENST00000616432.4 ENST00000416823.1 ENST00000428622.1	GAS2L1 Links Ensembl NCBI GeneCards UniProt Show fit	growth arrest specific 2 like 1
chr20_-_36746053 Show fit	0.76	ENST00000373803.6 ENST00000359675.6 ENST00000349004.6	NDRG3 Links Ensembl NCBI GeneCards UniProt Show fit	NDRG family member 3
chr22_+_29307005 Show fit	0.74	ENST00000406549.7 ENST00000610653.4 ENST00000621062.4 ENST00000611648.2 ENST00000618518.3	GAS2L1 Links Ensembl NCBI GeneCards UniProt Show fit	growth arrest specific 2 like 1
chr8_-_29263063 Show fit	0.73	ENST00000524189.6	KIF13B Links Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 13B
chr2_-_179264757 Show fit	0.73	ENST00000428443.8	SESTD1 Links Ensembl NCBI GeneCards UniProt Show fit	SEC14 and spectrin domain containing 1
chr2_-_69643152 Show fit	0.73	ENST00000606389.7	AAK1 Links Ensembl NCBI GeneCards UniProt Show fit	AP2 associated kinase 1
chr6_+_16238554 Show fit	0.69	ENST00000259727.5	GMPR Links Ensembl NCBI GeneCards UniProt Show fit	guanosine monophosphate reductase
chr8_+_143734133 Show fit	0.68	ENST00000527139.7 ENST00000533004.5	IQANK1 Links Ensembl NCBI GeneCards UniProt Show fit	IQ motif and ankyrin repeat containing 1
chr12_-_15882261 Show fit	0.66	ENST00000646918.1 ENST00000647087.1 ENST00000535752.5	EPS8 Links Ensembl NCBI GeneCards UniProt Show fit	epidermal growth factor receptor pathway substrate 8
chr5_-_115816650 Show fit	0.64	ENST00000250535.5	CDO1 Links Ensembl NCBI GeneCards UniProt Show fit	cysteine dioxygenase type 1
chr22_+_41092869 Show fit	0.64	ENST00000674155.1	EP300 Links Ensembl NCBI GeneCards UniProt Show fit	E1A binding protein p300
chr2_-_219571529 Show fit	0.64	ENST00000404537.6	OBSL1 Links Ensembl NCBI GeneCards UniProt Show fit	obscurin like cytoskeletal adaptor 1
chr13_+_41457543 Show fit	0.63	ENST00000379359.4	RGCC Links Ensembl NCBI GeneCards UniProt Show fit	regulator of cell cycle
chr2_-_27489716 Show fit	0.63	ENST00000260570.8 ENST00000675690.1	IFT172 Links Ensembl NCBI GeneCards UniProt Show fit	intraflagellar transport 172
chr1_+_156893678 Show fit	0.63	ENST00000292357.8 ENST00000338302.7 ENST00000455314.5	PEAR1 Links Ensembl NCBI GeneCards UniProt Show fit	platelet endothelial aggregation receptor 1
chr8_+_144466317 Show fit	0.61	ENST00000645548.2 ENST00000642354.1 ENST00000301332.3	KIFC2 Links Ensembl NCBI GeneCards UniProt Show fit	kinesin family member C2
chr2_-_27323006 Show fit	0.61	ENST00000402310.5 ENST00000405983.5 ENST00000403262.6	MPV17 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial inner membrane protein MPV17
chr10_-_50623897 Show fit	0.60	ENST00000361781.7 ENST00000429490.5 ENST00000619438.4	SGMS1 Links Ensembl NCBI GeneCards UniProt Show fit	sphingomyelin synthase 1
chr22_-_18936142 Show fit	0.59	ENST00000438924.5 ENST00000457083.1 ENST00000357068.11 ENST00000420436.5 ENST00000334029.6 ENST00000610940.4	PRODH Links Ensembl NCBI GeneCards UniProt Show fit	proline dehydrogenase 1
chr2_-_69643615 Show fit	0.59	ENST00000409068.5	AAK1 Links Ensembl NCBI GeneCards UniProt Show fit	AP2 associated kinase 1
chr22_+_46674593 Show fit	0.58	ENST00000408031.1	GRAMD4 Links Ensembl NCBI GeneCards UniProt Show fit	GRAM domain containing 4
chr21_-_39313578 Show fit	0.57	ENST00000380800.7	BRWD1 Links Ensembl NCBI GeneCards UniProt Show fit	bromodomain and WD repeat domain containing 1
chr5_+_10353668 Show fit	0.57	ENST00000274140.10 ENST00000449913.6 ENST00000503788.5	MARCHF6 Links Ensembl NCBI GeneCards UniProt Show fit	membrane associated ring-CH-type finger 6
chr2_-_191150971 Show fit	0.57	ENST00000409995.5 ENST00000392320.7	STAT4 Links Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 4
chr3_-_126056786 Show fit	0.56	ENST00000383598.6	SLC41A3 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 41 member 3
chr10_-_100185993 Show fit	0.56	ENST00000421367.7 ENST00000370408.2 ENST00000407654.7	ERLIN1 Links Ensembl NCBI GeneCards UniProt Show fit	ER lipid raft associated 1
chr9_+_128882502 Show fit	0.56	ENST00000259324.5	LRRC8A Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 8 VRAC subunit A
chr19_-_46023046 Show fit	0.55	ENST00000008938.5	PGLYRP1 Links Ensembl NCBI GeneCards UniProt Show fit	peptidoglycan recognition protein 1
chrX_+_47585212 Show fit	0.55	ENST00000445623.1	TIMP1 Links Ensembl NCBI GeneCards UniProt Show fit	TIMP metallopeptidase inhibitor 1
chr10_+_134465 Show fit	0.55	ENST00000439456.5 ENST00000397962.8 ENST00000309776.8 ENST00000397959.7	ZMYND11 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger MYND-type containing 11
chr1_-_109397888 Show fit	0.54	ENST00000256637.8	SORT1 Links Ensembl NCBI GeneCards UniProt Show fit	sortilin 1
chr17_+_68512878 Show fit	0.54	ENST00000585981.5 ENST00000589480.5 ENST00000585815.5	PRKAR1A Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase cAMP-dependent type I regulatory subunit alpha
chr1_-_52921681 Show fit	0.54	ENST00000467988.2 ENST00000358358.9 ENST00000371522.9 ENST00000536120.5	ECHDC2 Links Ensembl NCBI GeneCards UniProt Show fit	enoyl-CoA hydratase domain containing 2
chr14_-_24634160 Show fit	0.53	ENST00000616551.1 ENST00000382542.5 ENST00000216341.9 ENST00000526004.1 ENST00000415355.7	GZMB Links Ensembl NCBI GeneCards UniProt Show fit	granzyme B
chrX_-_101659796 Show fit	0.53	ENST00000431597.5 ENST00000458024.5 ENST00000413506.5 ENST00000440675.5 ENST00000328766.9 ENST00000356824.9	ARMCX2 Links Ensembl NCBI GeneCards UniProt Show fit	armadillo repeat containing X-linked 2
chr11_-_65047861 Show fit	0.53	ENST00000533842.5 ENST00000532802.5 ENST00000530139.2 ENST00000526516.5	NAALADL1 Links Ensembl NCBI GeneCards UniProt Show fit	N-acetylated alpha-linked acidic dipeptidase like 1
chr6_-_32190170 Show fit	0.53	ENST00000375050.6	PBX2 Links Ensembl NCBI GeneCards UniProt Show fit	PBX homeobox 2
chr3_+_127672925 Show fit	0.53	ENST00000232744.13 ENST00000453791.6	ABTB1 Links Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat and BTB domain containing 1
chr2_+_202634960 Show fit	0.51	ENST00000392238.3	FAM117B Links Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 117 member B
chr14_-_24634266 Show fit	0.51	ENST00000382540.5	GZMB Links Ensembl NCBI GeneCards UniProt Show fit	granzyme B
chr14_+_104724221 Show fit	0.50	ENST00000330877.7	ADSS1 Links Ensembl NCBI GeneCards UniProt Show fit	adenylosuccinate synthase 1
chrX_-_20266834 Show fit	0.49	ENST00000379565.9	RPS6KA3 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase A3
chr12_+_53006422 Show fit	0.49	ENST00000551002.5 ENST00000420463.7 ENST00000262056.14 ENST00000416762.7 ENST00000549481.5 ENST00000552490.5	EIF4B Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 4B
chr12_-_79690814 Show fit	0.49	ENST00000548426.1	PAWR Links Ensembl NCBI GeneCards UniProt Show fit	pro-apoptotic WT1 regulator
chr19_-_4581755 Show fit	0.49	ENST00000676793.1	SEMA6B Links Ensembl NCBI GeneCards UniProt Show fit	semaphorin 6B
chr11_-_65540610 Show fit	0.48	ENST00000532661.5	LTBP3 Links Ensembl NCBI GeneCards UniProt Show fit	latent transforming growth factor beta binding protein 3
chrX_+_111681650 Show fit	0.48	ENST00000436609.5 ENST00000482742.5 ENST00000623189.1	ALG13 Links Ensembl NCBI GeneCards UniProt Show fit	ALG13 UDP-N-acetylglucosaminyltransferase subunit
chr9_+_128882119 Show fit	0.48	ENST00000372600.9 ENST00000372599.7	LRRC8A Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 8 VRAC subunit A
chr19_-_18896081 Show fit	0.47	ENST00000429504.6 ENST00000623882.4 ENST00000247005.8	CERS1 Links Ensembl NCBI GeneCards UniProt Show fit GDF1 Links Ensembl NCBI GeneCards UniProt Show fit	ceramide synthase 1 growth differentiation factor 1
chr11_-_236821 Show fit	0.46	ENST00000529382.5 ENST00000528469.1	SIRT3 Links Ensembl NCBI GeneCards UniProt Show fit	sirtuin 3
chr12_-_79690957 Show fit	0.46	ENST00000328827.9	PAWR Links Ensembl NCBI GeneCards UniProt Show fit	pro-apoptotic WT1 regulator
chr1_-_53940100 Show fit	0.46	ENST00000371376.1	HSPB11 Links Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family B (small) member 11
chrX_-_20266606 Show fit	0.45	ENST00000643085.1 ENST00000645270.1 ENST00000644368.1	RPS6KA3 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase A3
chr4_+_83035159 Show fit	0.44	ENST00000509317.5 ENST00000264389.7 ENST00000503682.5 ENST00000511653.1	COPS4 Links Ensembl NCBI GeneCards UniProt Show fit	COP9 signalosome subunit 4
chr14_+_22543179 Show fit	0.44	ENST00000390534.1	TRAJ3 Links Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha joining 3
chr17_-_7262343 Show fit	0.44	ENST00000571881.2 ENST00000360325.11	CLDN7 Links Ensembl NCBI GeneCards UniProt Show fit	claudin 7
chrX_+_111681118 Show fit	0.44	ENST00000371979.7 ENST00000610588.4 ENST00000251943.8 ENST00000621367.4 ENST00000394780.8 ENST00000473389.5 ENST00000622986.3 ENST00000623255.1	ALG13 Links Ensembl NCBI GeneCards UniProt Show fit	ALG13 UDP-N-acetylglucosaminyltransferase subunit
chr2_+_130181662 Show fit	0.43	ENST00000425361.5 ENST00000457492.5	MZT2B Links Ensembl NCBI GeneCards UniProt Show fit	mitotic spindle organizing protein 2B
chr11_+_45922640 Show fit	0.42	ENST00000401752.6 ENST00000325468.9	LARGE2 Links Ensembl NCBI GeneCards UniProt Show fit	LARGE xylosyl- and glucuronyltransferase 2
chr2_-_27323072 Show fit	0.42	ENST00000428910.5 ENST00000402722.5 ENST00000380044.6 ENST00000399052.8 ENST00000405076.5	MPV17 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial inner membrane protein MPV17
chr7_+_832470 Show fit	0.41	ENST00000401592.6	SUN1 Links Ensembl NCBI GeneCards UniProt Show fit	Sad1 and UNC84 domain containing 1
chr2_-_27322564 Show fit	0.41	ENST00000233545.6	MPV17 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial inner membrane protein MPV17
chr7_-_156893150 Show fit	0.41	ENST00000353442.10	LMBR1 Links Ensembl NCBI GeneCards UniProt Show fit	limb development membrane protein 1
chr11_-_417304 Show fit	0.40	ENST00000397632.7	SIGIRR Links Ensembl NCBI GeneCards UniProt Show fit	single Ig and TIR domain containing
chrX_-_20266995 Show fit	0.40	ENST00000644893.1 ENST00000642835.1 ENST00000646610.1	RPS6KA3 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase A3
chr6_-_107115493 Show fit	0.40	ENST00000369042.6	BEND3 Links Ensembl NCBI GeneCards UniProt Show fit	BEN domain containing 3
chr2_+_74549026 Show fit	0.39	ENST00000409429.5	DOK1 Links Ensembl NCBI GeneCards UniProt Show fit	docking protein 1
chr2_+_69013282 Show fit	0.39	ENST00000409829.7	ANTXR1 Links Ensembl NCBI GeneCards UniProt Show fit	ANTXR cell adhesion molecule 1
chr6_+_41638438 Show fit	0.37	ENST00000441667.5 ENST00000230321.11 ENST00000373050.8 ENST00000446650.1 ENST00000435476.1	MDFI Links Ensembl NCBI GeneCards UniProt Show fit	MyoD family inhibitor
chr3_+_49674344 Show fit	0.37	ENST00000296456.10 ENST00000442186.5 ENST00000438011.5 ENST00000457042.1	APEH Links Ensembl NCBI GeneCards UniProt Show fit	acylaminoacyl-peptide hydrolase
chr2_+_27123798 Show fit	0.37	ENST00000316470.9 ENST00000416071.1	ABHD1 Links Ensembl NCBI GeneCards UniProt Show fit	abhydrolase domain containing 1
chr17_-_75271223 Show fit	0.37	ENST00000579297.5 ENST00000580571.5 ENST00000325102.13	MIF4GD Links Ensembl NCBI GeneCards UniProt Show fit	MIF4G domain containing
chr1_+_155308930 Show fit	0.36	ENST00000465559.5 ENST00000612683.1	FDPS Links Ensembl NCBI GeneCards UniProt Show fit	farnesyl diphosphate synthase
chr1_+_155308748 Show fit	0.36	ENST00000611010.4 ENST00000447866.5 ENST00000368356.9 ENST00000467076.5 ENST00000491013.5 ENST00000356657.10	FDPS Links Ensembl NCBI GeneCards UniProt Show fit	farnesyl diphosphate synthase
chrX_+_136497079 Show fit	0.36	ENST00000535601.5 ENST00000448450.5 ENST00000425695.5	HTATSF1 Links Ensembl NCBI GeneCards UniProt Show fit	HIV-1 Tat specific factor 1
chr17_-_75270999 Show fit	0.35	ENST00000579194.6 ENST00000580717.5 ENST00000577542.5 ENST00000579612.5 ENST00000245551.9 ENST00000578305.5	MIF4GD Links Ensembl NCBI GeneCards UniProt Show fit	MIF4G domain containing
chr22_-_31346143 Show fit	0.35	ENST00000405309.7 ENST00000351933.8	PATZ1 Links Ensembl NCBI GeneCards UniProt Show fit	POZ/BTB and AT hook containing zinc finger 1
chr1_-_25906457 Show fit	0.35	ENST00000426559.6	STMN1 Links Ensembl NCBI GeneCards UniProt Show fit	stathmin 1
chr4_+_155759365 Show fit	0.35	ENST00000513437.1	GUCY1B1 Links Ensembl NCBI GeneCards UniProt Show fit	guanylate cyclase 1 soluble subunit beta 1
chr1_-_50960230 Show fit	0.35	ENST00000396153.7	FAF1 Links Ensembl NCBI GeneCards UniProt Show fit	Fas associated factor 1
chr9_-_137188540 Show fit	0.35	ENST00000323927.3	ANAPC2 Links Ensembl NCBI GeneCards UniProt Show fit	anaphase promoting complex subunit 2
chr8_+_86514416 Show fit	0.34	ENST00000517490.6 ENST00000621783.4 ENST00000620393.4 ENST00000621526.4 ENST00000621245.4 ENST00000523469.5 ENST00000522240.1	CPNE3 Links Ensembl NCBI GeneCards UniProt Show fit	copine 3
chr7_-_105691637 Show fit	0.34	ENST00000472195.1	ATXN7L1 Links Ensembl NCBI GeneCards UniProt Show fit	ataxin 7 like 1
chr11_+_66857056 Show fit	0.34	ENST00000309602.5 ENST00000393952.3	LRFN4 Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat and fibronectin type III domain containing 4
chr16_-_1773113 Show fit	0.33	ENST00000397375.7 ENST00000177742.7	MRPS34 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein S34
chr19_-_36054224 Show fit	0.33	ENST00000292894.2	THAP8 Links Ensembl NCBI GeneCards UniProt Show fit	THAP domain containing 8
chr17_-_75270710 Show fit	0.33	ENST00000581777.2	MIF4GD Links Ensembl NCBI GeneCards UniProt Show fit	MIF4G domain containing
chr4_-_177442427 Show fit	0.33	ENST00000264595.7	AGA Links Ensembl NCBI GeneCards UniProt Show fit	aspartylglucosaminidase
chr13_-_75537805 Show fit	0.33	ENST00000626103.1 ENST00000682242.1 ENST00000355801.4	COMMD6 Links Ensembl NCBI GeneCards UniProt Show fit	COMM domain containing 6
chr2_+_69013379 Show fit	0.32	ENST00000409349.7	ANTXR1 Links Ensembl NCBI GeneCards UniProt Show fit	ANTXR cell adhesion molecule 1
chr1_-_167090370 Show fit	0.32	ENST00000367868.4	GPA33 Links Ensembl NCBI GeneCards UniProt Show fit	glycoprotein A33
chr4_-_151015263 Show fit	0.31	ENST00000510413.5 ENST00000507224.5 ENST00000651943.2	LRBA Links Ensembl NCBI GeneCards UniProt Show fit	LPS responsive beige-like anchor protein
chr17_-_75271205 Show fit	0.31	ENST00000649805.1	MIF4GD Links Ensembl NCBI GeneCards UniProt Show fit	MIF4G domain containing
chr19_-_1401487 Show fit	0.31	ENST00000640762.1 ENST00000252288.8 ENST00000447102.8	GAMT Links Ensembl NCBI GeneCards UniProt Show fit	guanidinoacetate N-methyltransferase
chr9_+_88388356 Show fit	0.31	ENST00000375859.4	SPIN1 Links Ensembl NCBI GeneCards UniProt Show fit	spindlin 1
chr20_+_58888779 Show fit	0.31	ENST00000488546.6 ENST00000667293.2 ENST00000481039.6 ENST00000467321.6	GNAS Links Ensembl NCBI GeneCards UniProt Show fit	GNAS complex locus
chr1_+_150364136 Show fit	0.31	ENST00000369068.5	RPRD2 Links Ensembl NCBI GeneCards UniProt Show fit	regulation of nuclear pre-mRNA domain containing 2
chr7_+_30969533 Show fit	0.31	ENST00000409904.7 ENST00000409316.5	GHRHR Links Ensembl NCBI GeneCards UniProt Show fit	growth hormone releasing hormone receptor
chr12_+_112013418 Show fit	0.31	ENST00000261735.4 ENST00000552052.1	ERP29 Links Ensembl NCBI GeneCards UniProt Show fit	endoplasmic reticulum protein 29
chr11_-_106077401 Show fit	0.30	ENST00000526793.5	KBTBD3 Links Ensembl NCBI GeneCards UniProt Show fit	kelch repeat and BTB domain containing 3
chr9_-_113299196 Show fit	0.30	ENST00000441031.3	RNF183 Links Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 183
chr22_+_46762617 Show fit	0.30	ENST00000380995.5 ENST00000337137.9 ENST00000407381.7	TBC1D22A Links Ensembl NCBI GeneCards UniProt Show fit	TBC1 domain family member 22A
chr11_-_106077313 Show fit	0.29	ENST00000531837.2 ENST00000534815.1	KBTBD3 Links Ensembl NCBI GeneCards UniProt Show fit	kelch repeat and BTB domain containing 3
chr16_-_726431 Show fit	0.29	ENST00000345165.10 ENST00000650995.1 ENST00000293889.10	CCDC78 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 78
chr19_+_676385 Show fit	0.29	ENST00000166139.9	FSTL3 Links Ensembl NCBI GeneCards UniProt Show fit	follistatin like 3
chr1_+_39081316 Show fit	0.29	ENST00000484793.5	MACF1 Links Ensembl NCBI GeneCards UniProt Show fit	microtubule actin crosslinking factor 1
chr3_-_38649668 Show fit	0.29	ENST00000333535.9 ENST00000413689.6 ENST00000423572.7	SCN5A Links Ensembl NCBI GeneCards UniProt Show fit	sodium voltage-gated channel alpha subunit 5
chr2_+_203936755 Show fit	0.29	ENST00000316386.11 ENST00000435193.1	ICOS Links Ensembl NCBI GeneCards UniProt Show fit	inducible T cell costimulator
chr8_+_74320832 Show fit	0.28	ENST00000676377.1	GDAP1 Links Ensembl NCBI GeneCards UniProt Show fit	ganglioside induced differentiation associated protein 1
chr1_+_53014926 Show fit	0.28	ENST00000430330.6 ENST00000408941.7 ENST00000478274.6 ENST00000484100.5 ENST00000435345.6 ENST00000488965.1	SCP2 Links Ensembl NCBI GeneCards UniProt Show fit	sterol carrier protein 2
chr22_+_46762677 Show fit	0.28	ENST00000355704.7	TBC1D22A Links Ensembl NCBI GeneCards UniProt Show fit	TBC1 domain family member 22A
chr17_-_49677976 Show fit	0.28	ENST00000665825.1 ENST00000508805.5 ENST00000515508.6 ENST00000451526.6 ENST00000507970.5	SPOP Links Ensembl NCBI GeneCards UniProt Show fit	speckle type BTB/POZ protein
chr7_+_101815904 Show fit	0.27	ENST00000437600.9 ENST00000645010.1 ENST00000646649.1	CUX1 Links Ensembl NCBI GeneCards UniProt Show fit	cut like homeobox 1
chr3_+_69739425 Show fit	0.27	ENST00000352241.9 ENST00000642352.1	MITF Links Ensembl NCBI GeneCards UniProt Show fit	melanocyte inducing transcription factor
chr20_+_13995369 Show fit	0.27	ENST00000217246.8 ENST00000684519.1 ENST00000642719.1	MACROD2 Links Ensembl NCBI GeneCards UniProt Show fit	mono-ADP ribosylhydrolase 2
chr9_-_113298865 Show fit	0.27	ENST00000416588.2	RNF183 Links Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 183
chr11_-_417385 Show fit	0.26	ENST00000332725.7	SIGIRR Links Ensembl NCBI GeneCards UniProt Show fit	single Ig and TIR domain containing
chr1_-_17011891 Show fit	0.26	ENST00000341676.9 ENST00000326735.13 ENST00000452699.5	ATP13A2 Links Ensembl NCBI GeneCards UniProt Show fit	ATPase cation transporting 13A2
chrX_+_136497586 Show fit	0.26	ENST00000218364.5	HTATSF1 Links Ensembl NCBI GeneCards UniProt Show fit	HIV-1 Tat specific factor 1
chr16_+_85611401 Show fit	0.26	ENST00000405402.6	GSE1 Links Ensembl NCBI GeneCards UniProt Show fit	Gse1 coiled-coil protein
chr13_-_96994350 Show fit	0.25	ENST00000298440.5 ENST00000543457.6 ENST00000541038.2	OXGR1 Links Ensembl NCBI GeneCards UniProt Show fit	oxoglutarate receptor 1
chr22_+_50343294 Show fit	0.25	ENST00000359139.7 ENST00000395741.7 ENST00000612753.5 ENST00000395744.7	PPP6R2 Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 6 regulatory subunit 2
chr4_-_140427635 Show fit	0.25	ENST00000325617.10 ENST00000414773.5	CLGN Links Ensembl NCBI GeneCards UniProt Show fit	calmegin
chr1_+_150549734 Show fit	0.25	ENST00000674043.1 ENST00000674058.1	ADAMTSL4 Links Ensembl NCBI GeneCards UniProt Show fit	ADAMTS like 4
chr17_-_7044091 Show fit	0.25	ENST00000574600.3 ENST00000662352.3 ENST00000673828.2	SLC16A11 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 16 member 11
chr1_+_39081410 Show fit	0.24	ENST00000602421.5 ENST00000361689.7	MACF1 Links Ensembl NCBI GeneCards UniProt Show fit	microtubule actin crosslinking factor 1
chr13_+_113667213 Show fit	0.24	ENST00000335678.7	GRK1 Links Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor kinase 1
chr7_+_832488 Show fit	0.24	ENST00000405266.5 ENST00000403868.5 ENST00000425407.6	SUN1 Links Ensembl NCBI GeneCards UniProt Show fit	Sad1 and UNC84 domain containing 1
chr13_-_96994730 Show fit	0.24	ENST00000541518.6	OXGR1 Links Ensembl NCBI GeneCards UniProt Show fit	oxoglutarate receptor 1
chr17_-_7043906 Show fit	0.24	ENST00000308009.5 ENST00000447225.1	SLC16A11 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 16 member 11
chr5_-_37371061 Show fit	0.24	ENST00000513532.1 ENST00000231498.8	NUP155 Links Ensembl NCBI GeneCards UniProt Show fit	nucleoporin 155
chr1_+_150364621 Show fit	0.24	ENST00000401000.8	RPRD2 Links Ensembl NCBI GeneCards UniProt Show fit	regulation of nuclear pre-mRNA domain containing 2
chr7_-_98252117 Show fit	0.24	ENST00000420697.1 ENST00000415086.5 ENST00000447648.7	TECPR1 Links Ensembl NCBI GeneCards UniProt Show fit	tectonin beta-propeller repeat containing 1
chr11_+_43680686 Show fit	0.23	ENST00000531185.5 ENST00000278353.10	HSD17B12 Links Ensembl NCBI GeneCards UniProt Show fit	hydroxysteroid 17-beta dehydrogenase 12
chr9_-_125189721 Show fit	0.23	ENST00000456642.1 ENST00000373547.9 ENST00000415905.5 ENST00000451402.5	PPP6C Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 6 catalytic subunit
chr1_+_95117923 Show fit	0.23	ENST00000455656.1 ENST00000604534.5	TLCD4 Links Ensembl NCBI GeneCards UniProt Show fit TLCD4-RWDD3 Links Ensembl NCBI GeneCards UniProt Show fit	TLC domain containing 4 TLCD4-RWDD3 readthrough
chr22_-_38700920 Show fit	0.23	ENST00000456626.1 ENST00000412832.1 ENST00000683374.1	JOSD1 Links Ensembl NCBI GeneCards UniProt Show fit	Josephin domain containing 1
chr6_+_33075952 Show fit	0.23	ENST00000418931.7	HLA-DPB1 Links Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DP beta 1
chr1_-_61725121 Show fit	0.23	ENST00000371177.2 ENST00000606498.5	TM2D1 Links Ensembl NCBI GeneCards UniProt Show fit	TM2 domain containing 1
chr9_+_113501359 Show fit	0.23	ENST00000343817.9 ENST00000394646.7	RGS3 Links Ensembl NCBI GeneCards UniProt Show fit	regulator of G protein signaling 3
chr21_-_41767071 Show fit	0.23	ENST00000352483.3	RIPK4 Links Ensembl NCBI GeneCards UniProt Show fit	receptor interacting serine/threonine kinase 4
chr1_-_31764035 Show fit	0.22	ENST00000373655.6	ADGRB2 Links Ensembl NCBI GeneCards UniProt Show fit	adhesion G protein-coupled receptor B2
chr21_-_41767042 Show fit	0.22	ENST00000332512.8	RIPK4 Links Ensembl NCBI GeneCards UniProt Show fit	receptor interacting serine/threonine kinase 4
chr22_-_38700655 Show fit	0.22	ENST00000216039.9	JOSD1 Links Ensembl NCBI GeneCards UniProt Show fit	Josephin domain containing 1
chr4_-_53591477 Show fit	0.21	ENST00000263925.8	LNX1 Links Ensembl NCBI GeneCards UniProt Show fit	ligand of numb-protein X 1
chr7_+_8433602 Show fit	0.21	ENST00000405863.6	NXPH1 Links Ensembl NCBI GeneCards UniProt Show fit	neurexophilin 1
chr4_-_143905529 Show fit	0.21	ENST00000358615.9 ENST00000437468.2	GYPE Links Ensembl NCBI GeneCards UniProt Show fit	glycophorin E (MNS blood group)
chr10_-_133308817 Show fit	0.21	ENST00000543663.6	TUBGCP2 Links Ensembl NCBI GeneCards UniProt Show fit	tubulin gamma complex associated protein 2
chr21_-_39313610 Show fit	0.21	ENST00000342449.8 ENST00000341322.4	BRWD1 Links Ensembl NCBI GeneCards UniProt Show fit	bromodomain and WD repeat domain containing 1
chr2_-_166375901 Show fit	0.21	ENST00000303354.11 ENST00000645907.1 ENST00000642356.2 ENST00000452182.2	SCN9A Links Ensembl NCBI GeneCards UniProt Show fit	sodium voltage-gated channel alpha subunit 9
chr11_+_60931744 Show fit	0.21	ENST00000536409.1	TMEM132A Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 132A
chr16_+_15434577 Show fit	0.21	ENST00000300006.9	BMERB1 Links Ensembl NCBI GeneCards UniProt Show fit	bMERB domain containing 1
chr10_+_133308874 Show fit	0.20	ENST00000361518.10 ENST00000359035.4	ZNF511 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 511
chr19_-_10587219 Show fit	0.20	ENST00000591240.5 ENST00000589684.5 ENST00000591676.1 ENST00000250244.11 ENST00000590923.5	AP1M2 Links Ensembl NCBI GeneCards UniProt Show fit	adaptor related protein complex 1 subunit mu 2

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	2.5	GO:0021592	fourth ventricle development(GO:0021592)
0.6	2.9	GO:1901202	negative regulation of extracellular matrix assembly(GO:1901202)
0.6	1.7	GO:0021793	chemorepulsion of branchiomotor axon(GO:0021793)
0.4	1.2	GO:0001300	chronological cell aging(GO:0001300)
0.4	2.0	GO:0016480	negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.4	2.7	GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.3	3.3	GO:0098881	exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.3	0.8	GO:0032877	positive regulation of DNA endoreduplication(GO:0032877)
0.3	0.8	GO:0036486	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.3	1.0	GO:0046368	GDP-L-fucose metabolic process(GO:0046368)
0.3	3.9	GO:0061299	retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.2	0.7	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.2	1.5	GO:0010481	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.2	0.6	GO:0042412	taurine biosynthetic process(GO:0042412)
0.2	1.2	GO:0046086	AMP catabolic process(GO:0006196) adenosine biosynthetic process(GO:0046086)
0.2	0.6	GO:0010133	proline catabolic process to glutamate(GO:0010133)
0.2	0.9	GO:0042986	positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.2	0.6	GO:0002325	natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.2	0.8	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.2	1.3	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.2	0.5	GO:1902462	regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.2	0.6	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.2	0.5	GO:0072720	response to dithiothreitol(GO:0072720)
0.2	1.8	GO:0042492	auditory receptor cell fate commitment(GO:0009912) gamma-delta T cell differentiation(GO:0042492) inner ear receptor cell fate commitment(GO:0060120)
0.1	1.0	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1	1.0	GO:0002329	pre-B cell differentiation(GO:0002329)
0.1	0.3	GO:1904017	cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1	1.9	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.1	0.5	GO:0033384	geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.1	0.7	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.1	1.4	GO:0032836	glomerular basement membrane development(GO:0032836)
0.1	0.4	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1	0.3	GO:0033277	abortive mitotic cell cycle(GO:0033277)
0.1	0.6	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1	1.1	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.1	0.3	GO:0060133	somatotropin secreting cell development(GO:0060133)
0.1	0.3	GO:0043335	protein unfolding(GO:0043335)
0.1	2.7	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1	0.6	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.1	2.3	GO:0014850	response to muscle activity(GO:0014850)
0.1	0.4	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
0.1	0.7	GO:0030473	nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	1.1	GO:0003334	keratinocyte development(GO:0003334)
0.1	1.1	GO:0016322	neuron remodeling(GO:0016322)
0.1	0.2	GO:0006212	uracil catabolic process(GO:0006212)
0.1	0.3	GO:0086048	membrane depolarization during bundle of His cell action potential(GO:0086048)
0.1	0.6	GO:1901164	negative regulation of membrane protein ectodomain proteolysis(GO:0051045) negative regulation of trophoblast cell migration(GO:1901164)
0.1	0.3	GO:0021997	neural plate axis specification(GO:0021997)
0.1	0.5	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.1	1.6	GO:2001275	positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.1	1.1	GO:0070986	left/right axis specification(GO:0070986)
0.0	1.5	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.0	0.2	GO:0018032	peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.0	0.7	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835) negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.3	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.0	0.7	GO:1902514	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0	0.5	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.0	0.6	GO:0040032	post-embryonic body morphogenesis(GO:0040032)
0.0	0.3	GO:0032380	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0	1.3	GO:0043555	regulation of translation in response to stress(GO:0043555)
0.0	1.5	GO:0090129	positive regulation of synapse maturation(GO:0090129)
0.0	0.3	GO:0046498	S-adenosylhomocysteine metabolic process(GO:0046498)
0.0	0.9	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	0.4	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.0	0.1	GO:1905246	regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0	1.3	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0	0.1	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
0.0	0.1	GO:0019878	lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.0	0.3	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.0	0.4	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0	1.5	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.1	GO:0060010	Sertoli cell fate commitment(GO:0060010)
0.0	0.5	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.0	0.2	GO:0001971	negative regulation of activation of membrane attack complex(GO:0001971)
0.0	1.0	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.0	0.4	GO:0000338	protein deneddylation(GO:0000338)
0.0	1.6	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.2	GO:0090435	protein localization to nuclear envelope(GO:0090435)
0.0	0.4	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.0	0.3	GO:0098535	de novo centriole assembly(GO:0098535)
0.0	0.2	GO:0051418	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0	0.4	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.0	0.4	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.0	0.2	GO:1900165	negative regulation of interleukin-6 secretion(GO:1900165)
0.0	0.3	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0	0.1	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
0.0	0.1	GO:1905000	regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0	0.2	GO:0061087	positive regulation of histone H3-K27 methylation(GO:0061087)
0.0	1.3	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.0	0.7	GO:0006144	purine nucleobase metabolic process(GO:0006144)
0.0	0.2	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.1	GO:0035965	cardiolipin acyl-chain remodeling(GO:0035965)
0.0	0.1	GO:0031133	regulation of axon diameter(GO:0031133)
0.0	1.1	GO:1904837	beta-catenin-TCF complex assembly(GO:1904837)
0.0	1.3	GO:0042733	embryonic digit morphogenesis(GO:0042733)
0.0	0.3	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.6	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.0	0.3	GO:0002517	T cell tolerance induction(GO:0002517)
0.0	0.0	GO:1903348	positive regulation of bicellular tight junction assembly(GO:1903348)
0.0	0.4	GO:0032463	negative regulation of protein homooligomerization(GO:0032463)
0.0	0.2	GO:2000774	positive regulation of cellular senescence(GO:2000774)
0.0	0.4	GO:0048266	behavioral response to pain(GO:0048266)
0.0	0.1	GO:0010796	regulation of multivesicular body size(GO:0010796)
0.0	0.1	GO:0032902	zygotic determination of anterior/posterior axis, embryo(GO:0007354) nerve growth factor production(GO:0032902)
0.0	0.1	GO:0034551	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0	0.1	GO:1904209	regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) positive regulation of metalloendopeptidase activity(GO:1904685)
0.0	0.0	GO:0034473	U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0	0.1	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	3.3	GO:1990796	photoreceptor cell terminal bouton(GO:1990796)
0.5	2.5	GO:0097513	myosin II filament(GO:0097513)
0.4	1.2	GO:0072563	endothelial microparticle(GO:0072563)
0.3	1.9	GO:1990393	3M complex(GO:1990393)
0.2	0.6	GO:0097598	sperm cytoplasmic droplet(GO:0097598)
0.1	0.7	GO:1902560	GMP reductase complex(GO:1902560)
0.1	0.9	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1	1.7	GO:0002116	semaphorin receptor complex(GO:0002116)
0.1	0.6	GO:0097013	phagocytic vesicle lumen(GO:0097013)
0.1	0.3	GO:1905103	integral component of lysosomal membrane(GO:1905103)
0.1	1.8	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1	0.2	GO:0044611	nuclear pore inner ring(GO:0044611)
0.1	2.9	GO:0031527	filopodium membrane(GO:0031527)
0.1	0.7	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	1.4	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	2.8	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.5	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.4	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.2	GO:0008275	gamma-tubulin small complex(GO:0008275)
0.0	0.3	GO:0098536	deuterosome(GO:0098536)
0.0	0.7	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0070435	Shc-EGFR complex(GO:0070435)
0.0	0.7	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952) nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.8	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.2	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.1	GO:1990769	proximal neuron projection(GO:1990769)
0.0	0.5	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.6	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.3	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.2	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.3	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.6	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.4	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	4.4	GO:0030018	Z disc(GO:0030018)
0.0	0.2	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.4	GO:0005686	U2 snRNP(GO:0005686)
0.0	1.1	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.4	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	1.5	GO:0043195	terminal bouton(GO:0043195)
0.0	0.5	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.2	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	1.5	GO:0072686	mitotic spindle(GO:0072686)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0004577	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity(GO:0004577)
0.3	1.1	GO:0016524	latrotoxin receptor activity(GO:0016524)
0.2	3.3	GO:0050544	arachidonic acid binding(GO:0050544)
0.2	2.0	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2	6.1	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.2	0.6	GO:0047493	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2	1.2	GO:0005534	galactose binding(GO:0005534)
0.1	0.7	GO:0016657	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1	0.6	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1	3.3	GO:0005112	Notch binding(GO:0005112)
0.1	0.3	GO:0033142	progesterone receptor binding(GO:0033142)
0.1	0.8	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1	2.5	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.1	0.5	GO:0004161	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1	0.3	GO:0070538	oleic acid binding(GO:0070538)
0.1	0.5	GO:0010465	nerve growth factor receptor activity(GO:0010465)
0.1	1.7	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.5	GO:0033592	RNA strand annealing activity(GO:0033592)
0.1	1.0	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.1	0.3	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.1	0.5	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	1.2	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.1	0.2	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.1	0.3	GO:0086062	voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1	1.3	GO:0035613	RNA stem-loop binding(GO:0035613)
0.1	0.3	GO:1903135	cupric ion binding(GO:1903135)
0.0	0.5	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.2	GO:0050254	rhodopsin kinase activity(GO:0050254)
0.0	1.6	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.4	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.2	GO:0004598	peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0	0.7	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.5	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	0.7	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.6	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.4	GO:0000182	rDNA binding(GO:0000182)
0.0	1.0	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0	0.7	GO:0043495	protein anchor(GO:0043495)
0.0	1.3	GO:0071889	14-3-3 protein binding(GO:0071889)
0.0	0.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.6	GO:0051430	corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0	0.1	GO:0008969	phosphohistidine phosphatase activity(GO:0008969)
0.0	0.1	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0	0.6	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	3.8	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.5	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.1	GO:0048408	epidermal growth factor binding(GO:0048408)
0.0	0.6	GO:0071949	FAD binding(GO:0071949)
0.0	0.4	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.1	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.4	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.9	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.5	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.1	GO:0001069	regulatory region RNA binding(GO:0001069)
0.0	0.6	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0	0.2	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.0	0.7	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.5	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.3	GO:0048185	activin binding(GO:0048185)
0.0	1.7	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	1.0	GO:0016836	hydro-lyase activity(GO:0016836)
0.0	0.4	GO:0008242	omega peptidase activity(GO:0008242)
0.0	1.1	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.4	GO:0031402	sodium ion binding(GO:0031402)
0.0	1.7	GO:0005518	collagen binding(GO:0005518)
0.0	0.1	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.0	0.7	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.4	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.5	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.3	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.1	0.6	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	1.8	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	1.0	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	1.4	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	1.3	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	1.2	PID ALK1 PATHWAY	ALK1 signaling events
0.0	1.5	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.4	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.6	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	2.5	PID P73PATHWAY	p73 transcription factor network
0.0	1.3	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.9	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.9	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.2	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	1.0	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	2.7	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	1.8	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.1	2.0	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	1.4	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.1	2.6	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.8	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	1.3	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.9	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.5	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.5	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.7	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.2	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.6	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	1.0	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	4.2	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	1.7	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.5	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	1.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.6	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.0	0.6	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.3	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.5	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	1.3	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.3	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.3	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.0	0.2	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.5	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.2	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus