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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for HNF1A_HNF1B

Z-value: 0.77

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Transcription factors associated with HNF1A_HNF1B

Gene Symbol Gene ID Gene Info
ENSG00000135100.19 HNF1A
ENSG00000275410.6 HNF1B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HNF1Bhg38_v1_chr17_-_37745018_377450690.376.8e-02Click!
HNF1Ahg38_v1_chr12_+_120978686_1209787490.242.5e-01Click!

Activity profile of HNF1A_HNF1B motif

Sorted Z-values of HNF1A_HNF1B motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HNF1A_HNF1B

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_-_154430495 2.48 ENST00000424998.3
CNKSR family member 3
chr10_+_97584314 1.51 ENST00000370647.8
4-hydroxy-2-oxoglutarate aldolase 1
chr16_-_69351778 1.16 ENST00000288025.4
transmembrane p24 trafficking protein 6
chr4_+_73481737 1.05 ENST00000226355.5
afamin
chr8_-_79767462 1.04 ENST00000674295.1
ENST00000518733.1
ENST00000674418.1
ENST00000674358.1
ENST00000354724.8
hes related family bHLH transcription factor with YRPW motif 1
chr2_+_27496830 0.99 ENST00000264717.7
glucokinase regulator
chr5_+_177087412 0.99 ENST00000513166.1
fibroblast growth factor receptor 4
chr15_+_67125707 0.91 ENST00000540846.6
SMAD family member 3
chr18_+_58341038 0.85 ENST00000679791.1
NEDD4 like E3 ubiquitin protein ligase
chr3_-_157503574 0.84 ENST00000494677.5
ENST00000468233.5
ventricular zone expressed PH domain containing 1
chr12_+_92702843 0.78 ENST00000397833.3
pleckstrin homology and RhoGEF domain containing G7
chr12_+_92702983 0.77 ENST00000344636.6
ENST00000544406.2
pleckstrin homology and RhoGEF domain containing G7
chr4_+_99574812 0.74 ENST00000422897.6
ENST00000265517.10
microsomal triglyceride transfer protein
chr22_-_30574572 0.72 ENST00000402369.5
galactose-3-O-sulfotransferase 1
chr16_-_55875299 0.72 ENST00000520435.2
carboxylesterase 5A
chr6_+_137871208 0.70 ENST00000614035.4
ENST00000621150.3
ENST00000619035.4
ENST00000615468.4
ENST00000620204.3
TNF alpha induced protein 3
chr1_+_17580474 0.68 ENST00000375415.5
Rho guanine nucleotide exchange factor 10 like
chr11_+_64555684 0.67 ENST00000377585.7
solute carrier family 22 member 11
chr16_-_57797764 0.64 ENST00000465878.6
ENST00000561524.5
kinesin family member C3
chr16_-_55875358 0.64 ENST00000319165.13
ENST00000290567.14
carboxylesterase 5A
chr17_-_66229380 0.63 ENST00000205948.11
apolipoprotein H
chr10_+_72692125 0.62 ENST00000373053.7
ENST00000357157.10
mitochondrial calcium uniporter
chr6_-_160664270 0.57 ENST00000316300.10
lipoprotein(a)
chr4_+_154563003 0.57 ENST00000302068.9
ENST00000509493.1
fibrinogen beta chain
chr20_+_44401397 0.56 ENST00000682427.1
ENST00000681977.1
ENST00000684136.1
ENST00000684046.1
ENST00000684476.1
ENST00000619550.5
ENST00000682169.1
hepatocyte nuclear factor 4 alpha
chr4_-_68670648 0.55 ENST00000338206.6
UDP glucuronosyltransferase family 2 member B15
chr12_-_39443390 0.54 ENST00000361961.7
kinesin family member 21A
chr14_-_94293071 0.52 ENST00000554723.5
serpin family A member 10
chr16_-_66918839 0.52 ENST00000565235.2
ENST00000568632.5
ENST00000565796.5
cadherin 16
chr16_-_66918876 0.52 ENST00000570262.5
ENST00000299752.9
ENST00000394055.7
cadherin 16
chr14_-_94293260 0.51 ENST00000261994.9
serpin family A member 10
chr14_-_94293024 0.51 ENST00000393096.5
serpin family A member 10
chrX_-_15664798 0.49 ENST00000380342.4
collectrin, amino acid transport regulator
chr2_-_96505345 0.48 ENST00000310865.7
ENST00000451794.6
neuralized E3 ubiquitin protein ligase 3
chr17_+_75646235 0.47 ENST00000556126.2
ENST00000579469.2
small integral membrane protein 6
chr11_+_64555924 0.47 ENST00000301891.9
solute carrier family 22 member 11
chr14_+_64704380 0.43 ENST00000247226.13
ENST00000394691.7
pleckstrin homology and RhoGEF domain containing G3
chr4_+_168092530 0.43 ENST00000359299.8
annexin A10
chr19_+_38647614 0.42 ENST00000252699.7
ENST00000424234.7
ENST00000440400.2
actinin alpha 4
chr11_-_107858777 0.41 ENST00000525815.6
solute carrier family 35 member F2
chr2_-_227379297 0.41 ENST00000304568.4
transmembrane 4 L six family member 20
chr20_+_44355692 0.40 ENST00000316673.8
ENST00000609795.5
ENST00000457232.5
ENST00000609262.5
hepatocyte nuclear factor 4 alpha
chr16_-_57798008 0.40 ENST00000421376.6
kinesin family member C3
chr3_-_138115594 0.40 ENST00000327532.7
ENST00000467030.5
DAZ interacting zinc finger protein 1 like
chr20_-_7940444 0.39 ENST00000378789.4
hydroxyacid oxidase 1
chr9_-_121050264 0.38 ENST00000223642.3
complement C5
chr13_-_103066411 0.37 ENST00000245312.5
solute carrier family 10 member 2
chr6_+_54308429 0.37 ENST00000259782.9
ENST00000370864.3
tubulointerstitial nephritis antigen
chr7_+_141995872 0.36 ENST00000497673.5
ENST00000620571.1
ENST00000475668.6
maltase-glucoamylase
chr19_+_38647679 0.36 ENST00000390009.7
ENST00000589528.1
actinin alpha 4
chr4_-_68951763 0.36 ENST00000251566.9
UDP glucuronosyltransferase family 2 member A3
chr10_+_97584347 0.35 ENST00000370649.3
ENST00000370646.9
novel protein
4-hydroxy-2-oxoglutarate aldolase 1
chr7_+_141995826 0.35 ENST00000549489.6
maltase-glucoamylase
chr16_-_87936529 0.35 ENST00000649794.3
ENST00000649158.1
ENST00000648177.1
carbonic anhydrase 5A
chr14_+_94561435 0.35 ENST00000557004.6
ENST00000555095.5
ENST00000298841.5
ENST00000554220.5
ENST00000553780.5
serpin family A member 4
serpin family A member 5
chr7_-_44541318 0.33 ENST00000381160.8
NPC1 like intracellular cholesterol transporter 1
chr1_-_159714581 0.33 ENST00000255030.9
ENST00000437342.1
ENST00000368112.5
ENST00000368111.5
ENST00000368110.1
C-reactive protein
chr14_-_57493827 0.32 ENST00000526336.1
ENST00000216445.8
coiled-coil domain containing 198
chr17_+_43211835 0.31 ENST00000588693.5
ENST00000588659.5
ENST00000541594.5
ENST00000536052.5
ENST00000612339.4
transmembrane protein 106A
chr16_+_21233672 0.31 ENST00000311620.7
ankyrin repeat and sterile alpha motif domain containing 4B
chr7_+_45888360 0.30 ENST00000457280.5
insulin like growth factor binding protein 1
chr3_+_75906666 0.30 ENST00000487694.7
ENST00000602589.5
roundabout guidance receptor 2
chr12_+_100357068 0.30 ENST00000323346.10
solute carrier family 17 member 8
chr10_+_110005804 0.29 ENST00000360162.7
adducin 3
chr1_+_103750406 0.29 ENST00000370079.3
amylase alpha 1C
chr8_-_69833338 0.29 ENST00000524945.5
solute carrier organic anion transporter family member 5A1
chr4_+_3441960 0.28 ENST00000382774.8
ENST00000511533.1
HGF activator
chr6_-_29045175 0.27 ENST00000377175.2
olfactory receptor family 2 subfamily W member 1
chr3_-_161372821 0.27 ENST00000617024.1
ENST00000359175.8
serine palmitoyltransferase small subunit B
chr1_+_119368773 0.27 ENST00000457318.5
ENST00000622548.4
ENST00000325945.4
hydroxyacid oxidase 2
chr6_+_167291309 0.26 ENST00000230256.8
unc-93 homolog A
chr17_+_4788926 0.25 ENST00000331264.8
glycolipid transfer protein domain containing 2
chr15_+_58138368 0.25 ENST00000219919.9
ENST00000536493.1
aquaporin 9
chr2_-_99301195 0.25 ENST00000308528.9
lysozyme g1
chr21_-_18403754 0.25 ENST00000284885.8
transmembrane serine protease 15
chr6_+_167291329 0.24 ENST00000366829.2
unc-93 homolog A
chr16_+_20451461 0.23 ENST00000574251.5
ENST00000573854.6
acyl-CoA synthetase medium chain family member 2A
chr9_+_137230757 0.23 ENST00000673865.1
ENST00000538474.5
ENST00000673835.1
ENST00000673953.1
ENST00000361134.2
solute carrier family 34 member 3
chr2_-_88128049 0.22 ENST00000393750.3
ENST00000295834.8
fatty acid binding protein 1
chr7_-_115968302 0.22 ENST00000457268.5
transcription factor EC
chrX_-_106038721 0.22 ENST00000372563.2
serpin family A member 7
chrX_-_15600953 0.22 ENST00000679212.1
ENST00000679278.1
ENST00000678046.1
ENST00000252519.8
angiotensin I converting enzyme 2
chr2_+_181986015 0.21 ENST00000409702.1
protein phosphatase 1 regulatory inhibitor subunit 1C
chr7_+_45888479 0.21 ENST00000275525.8
ENST00000468955.1
insulin like growth factor binding protein 1
chr17_+_42900791 0.21 ENST00000592383.5
ENST00000253801.7
ENST00000585489.1
glucose-6-phosphatase catalytic subunit 1
chr6_-_25874212 0.21 ENST00000361703.10
ENST00000397060.8
solute carrier family 17 member 3
chr1_+_48222685 0.20 ENST00000533824.5
ENST00000236495.9
ENST00000438567.7
solute carrier family 5 member 9
chr22_-_38110675 0.20 ENST00000381669.8
BAR/IMD domain containing adaptor protein 2 like 2
chr8_-_86743626 0.20 ENST00000320005.6
cyclic nucleotide gated channel subunit beta 3
chr11_-_117824734 0.20 ENST00000292079.7
FXYD domain containing ion transport regulator 2
chr11_+_2384603 0.20 ENST00000527343.5
ENST00000464784.6
CD81 molecule
chr5_+_68290637 0.19 ENST00000336483.9
phosphoinositide-3-kinase regulatory subunit 1
chr6_+_63521738 0.19 ENST00000648894.1
ENST00000639568.2
protein tyrosine phosphatase 4A1
chr17_+_28473635 0.19 ENST00000314669.10
ENST00000545060.2
solute carrier family 13 member 2
chr3_-_192727500 0.18 ENST00000430714.5
ENST00000418610.1
ENST00000445105.7
ENST00000684728.1
ENST00000448795.5
ENST00000683935.1
ENST00000684282.1
ENST00000683451.1
fibroblast growth factor 12
chr4_-_154590735 0.18 ENST00000403106.8
ENST00000622532.1
ENST00000651975.1
fibrinogen alpha chain
chr2_+_181985846 0.18 ENST00000682840.1
ENST00000409137.7
ENST00000280295.7
protein phosphatase 1 regulatory inhibitor subunit 1C
chr6_+_125749623 0.18 ENST00000368364.4
hes related family bHLH transcription factor with YRPW motif 2
chrX_-_124963768 0.18 ENST00000371130.7
ENST00000422452.2
teneurin transmembrane protein 1
chr22_+_44702186 0.18 ENST00000336985.11
ENST00000403696.5
ENST00000457960.5
ENST00000361473.9
proline rich 5
PRR5-ARHGAP8 readthrough
chr12_-_91180365 0.17 ENST00000547937.5
decorin
chr5_-_139383284 0.17 ENST00000353963.7
ENST00000348729.8
solute carrier family 23 member 1
chr15_+_86079863 0.17 ENST00000614907.3
ENST00000441037.7
ATP/GTP binding protein like 1
chr12_-_18090185 0.17 ENST00000229002.6
ENST00000538724.6
RERG like
chr10_-_126670686 0.17 ENST00000488181.3
chromosome 10 open reading frame 90
chrX_+_1591590 0.17 ENST00000313871.9
ENST00000381261.8
A-kinase anchoring protein 17A
chr3_-_165078480 0.16 ENST00000264382.8
sucrase-isomaltase
chr1_+_103617427 0.16 ENST00000423678.2
ENST00000414303.7
amylase alpha 2A
chr3_+_63443076 0.16 ENST00000295894.9
synaptoporin
chr16_+_81238682 0.15 ENST00000258168.7
ENST00000564552.1
beta-carotene oxygenase 1
chr4_+_39406917 0.15 ENST00000257408.5
klotho beta
chr4_-_1173168 0.15 ENST00000514490.5
ENST00000431380.5
ENST00000503765.5
spondin 2
chr6_+_12717660 0.15 ENST00000674637.1
phosphatase and actin regulator 1
chr9_-_91950201 0.15 ENST00000375708.4
receptor tyrosine kinase like orphan receptor 2
chr4_-_99352730 0.15 ENST00000510055.5
ENST00000515683.6
ENST00000511397.3
alcohol dehydrogenase 1C (class I), gamma polypeptide
chr3_-_142963663 0.15 ENST00000340634.6
progestin and adipoQ receptor family member 9
chr1_-_197067234 0.14 ENST00000367412.2
coagulation factor XIII B chain
chr7_-_88226987 0.14 ENST00000394641.7
sorcin
chr11_+_46719193 0.14 ENST00000311907.10
ENST00000530231.5
ENST00000442468.1
coagulation factor II, thrombin
chr7_-_88226965 0.14 ENST00000490437.5
ENST00000431660.5
sorcin
chr12_+_69738853 0.14 ENST00000247833.12
ENST00000378815.10
ENST00000483530.6
RAB3A interacting protein
chr12_+_18242955 0.14 ENST00000676171.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr17_+_28473278 0.14 ENST00000444914.7
solute carrier family 13 member 2
chr12_+_100473951 0.14 ENST00000648861.1
ENST00000546380.1
nuclear receptor subfamily 1 group H member 4
chr4_+_73404255 0.14 ENST00000621628.4
ENST00000621085.4
ENST00000415165.6
ENST00000295897.9
ENST00000503124.5
ENST00000509063.5
ENST00000401494.7
albumin
chr11_-_26722051 0.14 ENST00000396005.8
solute carrier family 5 member 12
chr11_+_114296347 0.13 ENST00000299964.4
nicotinamide N-methyltransferase
chr6_-_127518875 0.13 ENST00000465909.2
ENST00000467753.1
SOGA family member 3
chr14_-_94388589 0.13 ENST00000402629.1
ENST00000556091.1
ENST00000393087.9
ENST00000554720.1
serpin family A member 1
chr19_+_6464229 0.13 ENST00000600229.6
ENST00000356762.7
crumbs cell polarity complex component 3
chr3_+_184230373 0.13 ENST00000426955.6
von Willebrand factor A domain containing 5B2
chr6_-_117425905 0.13 ENST00000368507.8
ROS proto-oncogene 1, receptor tyrosine kinase
chr4_+_73436198 0.13 ENST00000395792.7
alpha fetoprotein
chr8_+_103880412 0.12 ENST00000436393.6
regulating synaptic membrane exocytosis 2
chr4_-_69653223 0.12 ENST00000286604.8
ENST00000505512.1
ENST00000514019.1
UDP glucuronosyltransferase family 2 member A1 complex locus
chr19_-_41627051 0.12 ENST00000221954.6
ENST00000600925.1
CEA cell adhesion molecule 4
chr10_+_84173793 0.12 ENST00000372126.4
chromosome 10 open reading frame 99
chr12_-_23949642 0.12 ENST00000537393.5
ENST00000451604.7
ENST00000381381.6
SRY-box transcription factor 5
chr10_-_73433550 0.12 ENST00000299432.7
MSS51 mitochondrial translational activator
chr6_-_117425855 0.12 ENST00000368508.7
ROS proto-oncogene 1, receptor tyrosine kinase
chr11_-_129024157 0.11 ENST00000392657.7
Rho GTPase activating protein 32
chr16_-_20576277 0.11 ENST00000566384.5
ENST00000565232.5
ENST00000567001.5
ENST00000565322.5
ENST00000569344.5
ENST00000329697.10
ENST00000568882.1
acyl-CoA synthetase medium chain family member 2B
chr13_+_33016415 0.11 ENST00000380099.4
klotho
chr10_+_133527355 0.11 ENST00000252945.8
ENST00000421586.5
ENST00000418356.1
cytochrome P450 family 2 subfamily E member 1
chr12_+_25052732 0.11 ENST00000547044.5
inositol 1,4,5-triphosphate receptor associated 2
chr11_+_1838970 0.10 ENST00000381911.6
troponin I2, fast skeletal type
chr19_+_53962925 0.10 ENST00000270458.4
calcium voltage-gated channel auxiliary subunit gamma 8
chr4_-_22443110 0.10 ENST00000508133.5
adhesion G protein-coupled receptor A3
chr6_+_160702238 0.10 ENST00000366924.6
ENST00000308192.14
ENST00000418964.1
plasminogen
chr12_+_100473708 0.10 ENST00000548884.5
ENST00000392986.8
nuclear receptor subfamily 1 group H member 4
chr7_-_44541262 0.10 ENST00000289547.8
ENST00000546276.5
ENST00000423141.1
NPC1 like intracellular cholesterol transporter 1
chr2_-_74328166 0.09 ENST00000358683.8
solute carrier family 4 member 5
chr11_-_65381951 0.09 ENST00000526432.5
ENST00000527174.5
solute carrier family 25 member 45
chr8_-_86230360 0.09 ENST00000419776.2
ENST00000297524.8
solute carrier family 7 member 13
chr5_+_141392616 0.09 ENST00000398604.3
protocadherin gamma subfamily A, 8
chr10_-_50885656 0.08 ENST00000374001.6
ENST00000395489.6
ENST00000282641.6
ENST00000395495.5
ENST00000373995.7
ENST00000414883.1
APOBEC1 complementation factor
chr6_-_116060859 0.08 ENST00000606080.2
fyn related Src family tyrosine kinase
chr4_-_99352754 0.08 ENST00000639454.1
alcohol dehydrogenase 1B (class I), beta polypeptide
chr6_+_106086316 0.08 ENST00000369091.6
ENST00000369096.9
PR/SET domain 1
chr8_-_94208548 0.08 ENST00000027335.8
ENST00000441892.6
ENST00000521491.1
cadherin 17
chr6_-_132763424 0.08 ENST00000532012.1
ENST00000525270.5
ENST00000530536.5
ENST00000524919.5
vanin 2
chr10_-_50885619 0.08 ENST00000373997.8
APOBEC1 complementation factor
chr3_+_186666003 0.08 ENST00000232003.5
histidine rich glycoprotein
chr8_-_107498041 0.08 ENST00000297450.7
angiopoietin 1
chr4_+_158521937 0.08 ENST00000343542.9
ENST00000470033.2
relaxin family peptide receptor 1
chr12_+_69739370 0.08 ENST00000550536.5
ENST00000362025.9
RAB3A interacting protein
chr4_+_158521872 0.07 ENST00000307765.10
relaxin family peptide receptor 1
chr6_-_52763473 0.07 ENST00000493422.3
glutathione S-transferase alpha 2
chr6_-_127519191 0.07 ENST00000525778.5
SOGA family member 3
chr1_+_116111395 0.07 ENST00000684484.1
ENST00000369500.4
mab-21 like 3
chr8_-_107497909 0.07 ENST00000517746.6
angiopoietin 1
chr22_+_32043253 0.07 ENST00000266088.9
solute carrier family 5 member 1
chr12_+_100503352 0.07 ENST00000551379.5
ENST00000188403.7
nuclear receptor subfamily 1 group H member 4
chr4_+_158521714 0.07 ENST00000613319.4
ENST00000423548.5
ENST00000448688.6
relaxin family peptide receptor 1
chr13_+_95433593 0.07 ENST00000376873.7
claudin 10
chr14_+_39233884 0.06 ENST00000553728.1
MIA SH3 domain ER export factor 2
chr15_+_85380565 0.06 ENST00000559362.5
ENST00000394518.7
A-kinase anchoring protein 13
chr12_-_102480552 0.06 ENST00000337514.11
ENST00000307046.8
insulin like growth factor 1
chr7_-_128910676 0.06 ENST00000620378.1
ENST00000610776.4
ENST00000613019.4
kielin cysteine rich BMP regulator
chr3_-_74521140 0.06 ENST00000263665.6
contactin 3
chr19_+_41796580 0.06 ENST00000357396.8
ENST00000630848.2
CEA cell adhesion molecule 3
chr20_+_58839741 0.06 ENST00000371098.6
ENST00000371075.7
ENST00000419558.7
ENST00000657090.1
GNAS complex locus
chr21_+_38256984 0.06 ENST00000398938.7
potassium inwardly rectifying channel subfamily J member 15
chr20_+_58839712 0.05 ENST00000313949.11
GNAS complex locus
chrX_+_108045050 0.05 ENST00000458383.1
ENST00000217957.10
V-set and immunoglobulin domain containing 1
chr11_-_83682414 0.05 ENST00000404783.7
discs large MAGUK scaffold protein 2
chr6_+_131250375 0.05 ENST00000474850.2
A-kinase anchoring protein 7
chr11_+_560956 0.05 ENST00000397582.7
ENST00000397583.8
Ras association domain family member 7
chr1_-_207032749 0.05 ENST00000359470.6
ENST00000461135.2
chromosome 1 open reading frame 116
chr16_+_14708944 0.04 ENST00000526520.5
ENST00000531598.6
nuclear pore complex interacting protein family member A3
chr14_-_64942783 0.04 ENST00000612794.1
glutathione peroxidase 2
chr4_+_73436244 0.04 ENST00000226359.2
alpha fetoprotein
chr19_+_6464491 0.04 ENST00000308243.7
crumbs cell polarity complex component 3
chr19_+_735026 0.04 ENST00000592155.5
ENST00000590161.2
paralemmin
chr9_+_79571767 0.04 ENST00000376544.7
TLE family member 4, transcriptional corepressor
chr6_+_29173303 0.04 ENST00000377167.3
olfactory receptor family 2 subfamily J member 2
chr14_-_64942720 0.03 ENST00000557049.1
ENST00000389614.6
glutathione peroxidase 2
chr10_-_32378720 0.03 ENST00000375110.6
enhancer of polycomb homolog 1
chr7_-_122304738 0.03 ENST00000442488.7
FEZ family zinc finger 1
chr6_+_31655888 0.03 ENST00000375916.4
apolipoprotein M

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.4 1.2 GO:0036304 umbilical cord morphogenesis(GO:0036304) umbilical cord development(GO:0061027)
0.3 1.5 GO:0008218 bioluminescence(GO:0008218)
0.2 0.7 GO:0070429 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.2 0.7 GO:0000023 maltose metabolic process(GO:0000023)
0.2 1.0 GO:0045218 zonula adherens maintenance(GO:0045218)
0.2 0.9 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.9 GO:1903412 response to bile acid(GO:1903412)
0.1 1.0 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.8 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417) positive regulation of pinocytosis(GO:0048549)
0.1 1.4 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 2.5 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 0.9 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.7 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.3 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.1 0.4 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.8 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.3 GO:0061107 seminal vesicle development(GO:0061107)
0.1 0.8 GO:0015747 urate transport(GO:0015747)
0.1 0.3 GO:2001250 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.1 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.3 GO:0015855 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.1 0.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.2 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.3 GO:0051801 cytolysis in other organism involved in symbiotic interaction(GO:0051801)
0.0 0.1 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.0 0.3 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 0.4 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.2 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.2 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0 0.2 GO:0016119 carotene metabolic process(GO:0016119)
0.0 0.3 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.3 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.3 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 0.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.2 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.4 GO:0098856 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.4 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.3 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 1.0 GO:0051180 vitamin transport(GO:0051180)
0.0 0.5 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.2 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0 0.1 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.2 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.2 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.0 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0036029 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.1 0.6 GO:1990246 uniplex complex(GO:1990246)
0.1 0.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.3 GO:0097441 basilar dendrite(GO:0097441)
0.1 1.0 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.3 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.3 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.8 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.8 GO:0005771 multivesicular body(GO:0005771)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0008431 vitamin E binding(GO:0008431)
0.3 1.2 GO:0035939 microsatellite binding(GO:0035939)
0.3 1.9 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.2 1.0 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 0.7 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.2 0.7 GO:0052852 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.2 0.9 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.6 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.3 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.3 GO:0033265 choline binding(GO:0033265)
0.1 1.0 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.7 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.3 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.1 0.3 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.1 0.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.2 GO:0008520 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.3 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.2 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.1 0.2 GO:0016160 amylase activity(GO:0016160)
0.0 0.3 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 1.0 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.2 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.8 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.3 GO:0032190 acrosin binding(GO:0032190)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.0 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.0 0.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.8 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.6 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.4 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.0 GO:1902271 D3 vitamins binding(GO:1902271)
0.0 0.1 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 1.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.2 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 2.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.3 GO:0015172 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.9 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.7 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.0 PID FGF PATHWAY FGF signaling pathway
0.0 0.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.4 PID E2F PATHWAY E2F transcription factor network
0.0 0.8 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 1.0 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.9 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.7 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 1.3 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 0.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 1.0 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.0 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.7 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism