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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for HNF4G

Z-value: 0.80

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Transcription factors associated with HNF4G

Gene Symbol Gene ID Gene Info
ENSG00000164749.13 HNF4G

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HNF4Ghg38_v1_chr8_+_75539862_75539892,
hg38_v1_chr8_+_75539893_75539968
0.087.2e-01Click!

Activity profile of HNF4G motif

Sorted Z-values of HNF4G motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HNF4G

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr12_-_94616061 5.63 ENST00000551457.1
transmembrane and coiled-coil domain family 3
chr4_+_41613476 2.47 ENST00000508466.1
LIM and calponin homology domains 1
chr17_+_70169516 2.19 ENST00000243457.4
potassium inwardly rectifying channel subfamily J member 2
chr1_+_61082398 2.06 ENST00000664149.1
nuclear factor I A
chr3_+_194136138 1.98 ENST00000232424.4
hes family bHLH transcription factor 1
chr20_-_64049631 1.98 ENST00000340356.9
SRY-box transcription factor 18
chr1_+_61082553 1.86 ENST00000403491.8
ENST00000371187.7
nuclear factor I A
chr4_+_42397473 1.76 ENST00000319234.5
shisa family member 3
chr20_+_43945677 1.67 ENST00000358131.5
TOX high mobility group box family member 2
chr11_-_118264282 1.63 ENST00000278937.7
myelin protein zero like 2
chr2_-_74440484 1.54 ENST00000305557.9
ENST00000233330.6
rhotekin
chrX_+_139530730 1.40 ENST00000218099.7
coagulation factor IX
chr17_-_5584448 1.26 ENST00000269280.8
ENST00000571451.6
ENST00000572272.6
ENST00000613500.4
ENST00000619223.4
ENST00000617618.4
ENST00000345221.7
ENST00000262467.10
NLR family pyrin domain containing 1
chr2_-_69643152 1.20 ENST00000606389.7
AP2 associated kinase 1
chr2_+_233060295 1.18 ENST00000445964.6
inositol polyphosphate-5-phosphatase D
chr9_+_137077467 1.14 ENST00000409858.8
UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
chr6_-_31897200 1.12 ENST00000395728.7
ENST00000375528.8
euchromatic histone lysine methyltransferase 2
chr1_+_61082702 1.11 ENST00000485903.6
ENST00000371185.6
ENST00000371184.6
nuclear factor I A
chr2_+_12716893 1.06 ENST00000381465.2
ENST00000155926.9
tribbles pseudokinase 2
chr22_-_37484505 1.04 ENST00000442496.1
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chrX_+_150363258 1.01 ENST00000683696.1
mastermind like domain containing 1
chr21_-_30487436 0.99 ENST00000334055.5
keratin associated protein 19-2
chr2_-_237590660 0.98 ENST00000409576.1
RAB17, member RAS oncogene family
chr2_+_3379668 0.95 ENST00000382110.6
ENST00000324266.10
trafficking protein particle complex 12
chrX_+_150363306 0.95 ENST00000370401.7
ENST00000432680.7
mastermind like domain containing 1
chr19_-_1812194 0.95 ENST00000525591.5
ATPase phospholipid transporting 8B3
chr12_+_2959870 0.94 ENST00000397122.6
TEA domain transcription factor 4
chr1_+_77888612 0.88 ENST00000334785.12
nexilin F-actin binding protein
chr9_-_109013483 0.84 ENST00000325551.9
ENST00000374593.4
ENST00000374595.8
catenin alpha like 1
chr19_-_11197516 0.83 ENST00000592903.5
ENST00000586659.6
ENST00000589359.5
ENST00000588724.5
KN motif and ankyrin repeat domains 2
chr19_+_45499610 0.82 ENST00000396735.6
protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)
chr17_-_7179348 0.82 ENST00000573083.1
ENST00000574388.5
ENST00000269299.8
asialoglycoprotein receptor 1
chr14_+_96039328 0.82 ENST00000553764.1
ENST00000555004.3
ENST00000556728.1
ENST00000553782.1
chromosome 14 open reading frame 132
chr11_+_104036624 0.82 ENST00000302259.5
DNA damage inducible 1 homolog 1
chr9_+_2015186 0.80 ENST00000357248.8
ENST00000450198.6
ENST00000634287.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr4_+_70734419 0.80 ENST00000502653.5
RUN and FYVE domain containing 3
chr5_-_113294895 0.80 ENST00000514701.5
ENST00000302475.8
MCC regulator of WNT signaling pathway
chr19_+_45499797 0.80 ENST00000401593.5
ENST00000396736.2
protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)
chr19_+_34254543 0.80 ENST00000588470.5
ENST00000299505.8
ENST00000589583.5
granule associated Rac and RHOG effector 1
chr1_+_77888490 0.79 ENST00000401035.7
ENST00000330010.12
nexilin F-actin binding protein
chr17_+_60600178 0.76 ENST00000629650.2
ENST00000305921.8
protein phosphatase, Mg2+/Mn2+ dependent 1D
chr12_+_13044371 0.76 ENST00000197268.13
family with sequence similarity 234 member B
chr11_-_119364166 0.75 ENST00000525735.1
ubiquitin specific peptidase 2
chr17_-_41521719 0.74 ENST00000393976.6
keratin 15
chr17_-_7179544 0.72 ENST00000619926.4
asialoglycoprotein receptor 1
chr1_+_20633450 0.72 ENST00000321556.5
PTEN induced kinase 1
chr9_+_2015335 0.72 ENST00000636559.1
ENST00000349721.8
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr14_+_23988884 0.71 ENST00000558753.5
ENST00000537912.5
dehydrogenase/reductase 4 like 2
chr21_-_45544392 0.71 ENST00000443742.1
ENST00000528477.1
ENST00000567670.5
solute carrier family 19 member 1
chr22_+_19962537 0.69 ENST00000449653.5
catechol-O-methyltransferase
chr8_+_22579139 0.69 ENST00000397761.6
PDZ and LIM domain 2
chr2_+_178194460 0.67 ENST00000392505.6
ENST00000359685.7
ENST00000357080.8
ENST00000190611.9
ENST00000409045.7
oxysterol binding protein like 6
chr3_-_158672612 0.67 ENST00000264265.4
latexin
chr12_+_3077355 0.66 ENST00000537971.5
ENST00000011898.10
ENST00000649909.1
tetraspanin 9
chr8_+_22579100 0.66 ENST00000452226.5
ENST00000397760.8
PDZ and LIM domain 2
chr3_-_126101506 0.66 ENST00000509064.5
ENST00000508835.5
solute carrier family 41 member 3
chr17_-_81911350 0.66 ENST00000570388.5
phosphate cytidylyltransferase 2, ethanolamine
chr11_+_67303497 0.66 ENST00000308127.9
slingshot protein phosphatase 3
chr17_+_81103998 0.65 ENST00000572498.1
BAR/IMD domain containing adaptor protein 2
chr2_+_48568981 0.65 ENST00000394754.5
STON1-GTF2A1L readthrough
chr20_-_37527723 0.65 ENST00000397135.1
ENST00000397137.5
BLCAP apoptosis inducing factor
chr2_+_90038848 0.65 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr6_-_144008364 0.65 ENST00000625622.2
PLAG1 like zinc finger 1
chr6_-_144008396 0.65 ENST00000354765.6
ENST00000416623.5
ENST00000649211.1
PLAG1 like zinc finger 1
chr9_-_76692181 0.64 ENST00000376717.6
ENST00000223609.10
prune homolog 2 with BCH domain
chr12_-_51270351 0.64 ENST00000603798.6
small cell adhesion glycoprotein
chr12_-_54419259 0.64 ENST00000293379.9
integrin subunit alpha 5
chr11_+_67303476 0.62 ENST00000376757.9
ENST00000308298.11
slingshot protein phosphatase 3
chr8_-_73746830 0.62 ENST00000524300.6
ENST00000523558.5
ENST00000521210.5
ENST00000355780.9
ENST00000524104.5
ENST00000521736.5
ENST00000521447.5
ENST00000517542.5
ENST00000521451.5
ENST00000521419.5
ENST00000518502.5
staufen double-stranded RNA binding protein 2
chr2_-_62506136 0.62 ENST00000335390.6
transmembrane protein 17
chr7_+_23181994 0.62 ENST00000410002.7
ENST00000258742.10
ENST00000413919.1
nucleoporin 42
chr2_+_85584402 0.61 ENST00000306384.5
vesicle associated membrane protein 5
chr10_-_49188380 0.61 ENST00000374153.7
ENST00000374148.1
ENST00000374151.7
transmembrane protein 273
chr18_-_55586092 0.60 ENST00000563888.6
ENST00000540999.5
ENST00000627685.2
transcription factor 4
chr12_-_46372763 0.59 ENST00000256689.10
solute carrier family 38 member 2
chr2_-_237590694 0.59 ENST00000264601.8
ENST00000411462.5
ENST00000409822.1
RAB17, member RAS oncogene family
chr6_-_30113086 0.58 ENST00000376734.4
tripartite motif containing 31
chr14_+_104579757 0.58 ENST00000331952.6
ENST00000557649.6
chromosome 14 open reading frame 180
chr22_-_19178402 0.57 ENST00000451283.5
solute carrier family 25 member 1
chr9_-_34376878 0.57 ENST00000297625.8
myogenesis regulating glycosidase (putative)
chr7_-_15561986 0.57 ENST00000342526.8
alkylglycerol monooxygenase
chr17_-_81911128 0.57 ENST00000573927.5
ENST00000331285.7
ENST00000572157.1
phosphate cytidylyltransferase 2, ethanolamine
chr16_-_24930952 0.57 ENST00000571406.1
Rho GTPase activating protein 17
chr21_-_38661694 0.56 ENST00000417133.6
ENST00000398910.5
ENST00000442448.5
ENST00000429727.6
ETS transcription factor ERG
chr6_-_83065770 0.56 ENST00000369747.8
ubiquitin protein ligase E3D
chr8_-_27611325 0.53 ENST00000523500.5
clusterin
chr5_+_1225379 0.53 ENST00000324642.4
solute carrier family 6 member 18
chr2_-_85602351 0.52 ENST00000409668.1
transmembrane protein 150A
chr20_+_59933761 0.51 ENST00000358293.7
family with sequence similarity 217 member B
chr9_+_2015275 0.51 ENST00000637103.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr14_+_22040576 0.51 ENST00000390448.3
T cell receptor alpha variable 20
chr16_-_67150951 0.51 ENST00000449549.4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr8_-_27611424 0.51 ENST00000405140.7
clusterin
chr18_-_55585773 0.51 ENST00000563824.5
ENST00000626425.2
ENST00000566514.5
ENST00000568673.5
ENST00000562847.5
ENST00000568147.5
transcription factor 4
chr4_+_88523810 0.50 ENST00000512194.2
ENST00000598772.1
ENST00000597259.2
HECT and RLD domain containing E3 ubiquitin protein ligase 3
PIGY divergent transcript
chr4_+_143336762 0.50 ENST00000262995.8
GRB2 associated binding protein 1
chr20_+_64063481 0.50 ENST00000415602.5
transcription elongation factor A2
chr16_+_4788411 0.50 ENST00000589327.5
small integral membrane protein 22
chr2_-_89143133 0.50 ENST00000492167.1
immunoglobulin kappa variable 3-20
chr6_-_84763437 0.50 ENST00000606784.5
ENST00000606325.5
T-box transcription factor 18
chr14_-_105065422 0.49 ENST00000329797.8
ENST00000539291.6
ENST00000392585.2
G protein-coupled receptor 132
chr19_-_15125095 0.49 ENST00000600984.5
ilvB acetolactate synthase like
chr12_+_10213417 0.49 ENST00000546017.5
ENST00000535576.5
ENST00000539170.5
GABA type A receptor associated protein like 1
chr1_-_19274151 0.49 ENST00000420396.3
aldo-keto reductase family 7 like (gene/pseudogene)
chr13_+_42272134 0.48 ENST00000025301.4
A-kinase anchoring protein 11
chr1_+_96722628 0.48 ENST00000675401.1
polypyrimidine tract binding protein 2
chr2_+_240452809 0.48 ENST00000420138.5
glypican 1
chr8_-_38468627 0.48 ENST00000683815.1
ENST00000684654.1
ENST00000447712.7
ENST00000397091.9
fibroblast growth factor receptor 1
chr17_+_63484840 0.47 ENST00000290863.10
ENST00000413513.7
angiotensin I converting enzyme
chr9_+_137086857 0.47 ENST00000682881.1
ENST00000683324.1
ENST00000542372.2
ENST00000683355.1
ENST00000682117.1
ENST00000682212.1
ENST00000684144.1
ENST00000683987.1
ENST00000371589.9
ENST00000535144.6
ENST00000475449.7
ENST00000684759.1
mannosidase alpha class 1B member 1
chr20_-_1184981 0.47 ENST00000429036.2
transmembrane protein 74B
chrX_-_120559889 0.47 ENST00000371323.3
cullin 4B
chr17_+_68247930 0.47 ENST00000580548.5
ENST00000612294.4
ENST00000580753.5
ENST00000392720.6
ENST00000359904.8
ENST00000359783.8
ENST00000584837.5
ENST00000579724.5
ENST00000584494.5
ENST00000580837.5
archaelysin family metallopeptidase 2
chr17_-_42423246 0.47 ENST00000357037.6
caveolae associated protein 1
chr9_-_20382461 0.47 ENST00000380321.5
ENST00000629733.3
MLLT3 super elongation complex subunit
chr22_-_37019434 0.47 ENST00000249042.8
ENST00000403892.7
thiosulfate sulfurtransferase
chr14_+_59484443 0.46 ENST00000356057.9
ENST00000425728.6
ENST00000616435.5
ENST00000556985.5
ENST00000554271.5
ENST00000554795.1
JNK1/MAPK8 associated membrane protein
chr2_-_241508630 0.46 ENST00000403346.7
ENST00000535007.5
serine/threonine kinase 25
chr6_-_69796870 0.46 ENST00000649011.1
LMBR1 domain containing 1
chr8_-_38468601 0.46 ENST00000341462.9
ENST00000683765.1
ENST00000356207.9
ENST00000326324.10
ENST00000335922.9
ENST00000532791.5
fibroblast growth factor receptor 1
chrX_-_15270031 0.46 ENST00000380483.7
ENST00000380485.7
ENST00000380488.9
ankyrin repeat and SOCS box containing 9
chr12_-_57826295 0.45 ENST00000549039.5
CTD small phosphatase 2
chr20_-_37527862 0.45 ENST00000373537.7
ENST00000445723.5
ENST00000414080.1
BLCAP apoptosis inducing factor
chr1_-_101025763 0.45 ENST00000342173.11
ENST00000488176.1
ENST00000370109.8
diphthamide biosynthesis 5
chr11_+_78188871 0.44 ENST00000528910.5
ENST00000529308.6
ubiquitin specific peptidase 35
chr2_+_190343561 0.43 ENST00000322522.8
ENST00000392329.7
ENST00000430311.5
inositol polyphosphate-1-phosphatase
chr6_-_32177061 0.43 ENST00000395499.5
1-acylglycerol-3-phosphate O-acyltransferase 1
chr6_-_41039202 0.43 ENST00000244565.8
unc-5 family C-terminal like
chr2_+_216659600 0.43 ENST00000456764.1
insulin like growth factor binding protein 2
chr16_-_90008988 0.42 ENST00000568662.2
dysbindin domain containing 1
chr3_-_58214671 0.42 ENST00000460422.1
ENST00000483681.5
deoxyribonuclease 1 like 3
chr1_+_27342014 0.42 ENST00000618673.4
ENST00000318074.9
ENST00000616558.5
synaptotagmin like 1
chr6_+_31959130 0.42 ENST00000375394.7
ENST00000628157.1
Ski2 like RNA helicase
chr6_-_69796971 0.42 ENST00000649934.3
LMBR1 domain containing 1
chr22_+_22747383 0.42 ENST00000390311.3
immunoglobulin lambda variable 3-16
chr17_+_3475959 0.42 ENST00000263080.3
aspartoacylase
chr11_-_1750558 0.41 ENST00000340134.5
interferon induced transmembrane protein 10
chr18_+_7754959 0.41 ENST00000400053.8
protein tyrosine phosphatase receptor type M
chr1_+_96721762 0.41 ENST00000675735.1
ENST00000609116.5
ENST00000674951.1
ENST00000426398.3
ENST00000370197.5
ENST00000370198.5
polypyrimidine tract binding protein 2
chr5_-_113434978 0.41 ENST00000390666.4
testis specific serine kinase 1B
chr13_+_41457543 0.41 ENST00000379359.4
regulator of cell cycle
chr12_+_20810698 0.41 ENST00000540853.5
ENST00000381545.8
solute carrier organic anion transporter family member 1B3
chr3_-_48635426 0.41 ENST00000455886.6
ENST00000431739.5
ENST00000426599.1
ENST00000383733.7
ENST00000395550.7
ENST00000420764.6
ENST00000337000.12
solute carrier family 26 member 6
chr11_+_119149029 0.41 ENST00000619701.5
ATP binding cassette subfamily G member 4
chr17_+_50547089 0.40 ENST00000619622.4
ENST00000356488.8
ENST00000006658.11
spermatogenesis associated 20
chr1_+_70205708 0.40 ENST00000370950.7
serine and arginine rich splicing factor 11
chr19_+_37346283 0.39 ENST00000541583.6
zinc finger protein 875
chr10_+_68560317 0.39 ENST00000373644.5
tet methylcytosine dioxygenase 1
chr11_-_118264445 0.39 ENST00000438295.2
myelin protein zero like 2
chr5_-_177006581 0.39 ENST00000506128.5
ubiquitin interaction motif containing 1
chr12_+_109098118 0.39 ENST00000336865.6
uracil DNA glycosylase
chr8_+_11808417 0.39 ENST00000525954.5
farnesyl-diphosphate farnesyltransferase 1
chr7_+_33129530 0.39 ENST00000671890.1
ENST00000350941.7
ENST00000396127.6
ENST00000355070.6
ENST00000671871.1
ENST00000673431.1
ENST00000671963.1
ENST00000242067.11
Bardet-Biedl syndrome 9
chr1_+_28236096 0.38 ENST00000497986.5
ENST00000335514.10
ENST00000468425.2
ENST00000465645.1
ATP synthase inhibitory factor subunit 1
chr9_+_128340646 0.38 ENST00000372870.5
solute carrier family 27 member 4
chr19_-_42302766 0.38 ENST00000595530.5
ENST00000538771.5
ENST00000601865.5
platelet activating factor acetylhydrolase 1b catalytic subunit 3
chr1_+_26543106 0.38 ENST00000530003.5
ribosomal protein S6 kinase A1
chr12_+_111766887 0.38 ENST00000416293.7
ENST00000261733.7
aldehyde dehydrogenase 2 family member
chr2_-_214809597 0.38 ENST00000619009.5
ENST00000421162.2
ENST00000617164.5
ENST00000613374.5
ENST00000620057.4
BRCA1 associated RING domain 1
chr6_+_2999885 0.38 ENST00000397717.7
ENST00000380455.11
N-ribosyldihydronicotinamide:quinone reductase 2
chr11_-_66729184 0.38 ENST00000533211.6
ENST00000309996.7
spectrin beta, non-erythrocytic 2
chr17_-_27793716 0.37 ENST00000646938.1
nitric oxide synthase 2
chr1_+_28369705 0.37 ENST00000373839.8
phosphatase and actin regulator 4
chr5_-_177006350 0.37 ENST00000377227.8
ubiquitin interaction motif containing 1
chr20_-_59007210 0.37 ENST00000681175.1
ENST00000681416.1
ENST00000680753.1
ENST00000680995.1
ENST00000680206.1
ENST00000680879.1
ENST00000217131.6
ENST00000680738.1
ENST00000679948.1
ENST00000680880.1
ENST00000681877.1
cathepsin Z
chr2_-_240682879 0.37 ENST00000407834.4
ENST00000621682.4
aquaporin 12B
chrX_+_118974608 0.37 ENST00000304778.11
ENST00000371628.8
LON peptidase N-terminal domain and ring finger 3
chr2_-_127642131 0.37 ENST00000426981.5
LIM zinc finger domain containing 2
chr3_+_49007062 0.37 ENST00000395474.7
ENST00000610967.4
ENST00000429900.6
WD repeat domain 6
chr7_+_92057602 0.37 ENST00000491695.2
A-kinase anchoring protein 9
chr1_+_26159071 0.37 ENST00000374268.5
family with sequence similarity 110 member D
chr11_+_3855629 0.37 ENST00000526596.2
ENST00000300737.8
ENST00000616714.4
stromal interaction molecule 1
chr3_-_128487916 0.36 ENST00000430265.6
GATA binding protein 2
chr11_-_65614195 0.36 ENST00000309100.8
ENST00000529839.1
ENST00000526293.1
mitogen-activated protein kinase kinase kinase 11
chr10_-_98415143 0.36 ENST00000370575.5
pyridine nucleotide-disulphide oxidoreductase domain 2
chr6_+_38715288 0.36 ENST00000327475.11
dynein axonemal heavy chain 8
chr6_+_27247690 0.35 ENST00000421826.6
ENST00000230582.8
serine protease 16
chr19_+_17952236 0.35 ENST00000682733.1
potassium calcium-activated channel subfamily N member 1
chr17_-_28718147 0.35 ENST00000436730.7
ENST00000625712.2
ENST00000450529.5
ENST00000583538.5
ENST00000419712.7
ENST00000580843.6
ENST00000582934.1
ENST00000415040.6
ENST00000353676.9
ENST00000453384.7
RAB34, member RAS oncogene family
chr1_+_236523932 0.35 ENST00000366584.9
ENST00000323938.10
galectin 8
chr11_-_117098415 0.35 ENST00000445177.6
ENST00000375300.6
ENST00000446921.6
SIK family kinase 3
chr11_-_116823293 0.35 ENST00000357780.5
apolipoprotein A4
chr4_+_143336868 0.35 ENST00000262994.8
GRB2 associated binding protein 1
chr10_-_17129786 0.35 ENST00000377833.10
cubilin
chr1_-_9069797 0.35 ENST00000473209.1
solute carrier family 2 member 5
chr20_-_63969890 0.35 ENST00000369888.6
zinc finger protein 512B
chr3_+_196712298 0.34 ENST00000392391.9
ENST00000296333.10
phosphatidylinositol glycan anchor biosynthesis class X
chr15_+_75043263 0.34 ENST00000563393.1
phosphopantothenoylcysteine decarboxylase
chr4_+_88457110 0.34 ENST00000264350.8
HECT and RLD domain containing E3 ubiquitin protein ligase 5
chr11_+_847197 0.34 ENST00000532375.5
ENST00000346501.8
tetraspanin 4
chr17_-_41440983 0.33 ENST00000246646.4
keratin 38
chr8_-_144416481 0.33 ENST00000276833.9
solute carrier family 39 member 4
chr15_+_37934626 0.33 ENST00000559502.5
ENST00000558148.5
ENST00000319669.5
ENST00000558158.5
transmembrane and coiled-coil domains 5A
chr8_+_22987400 0.33 ENST00000519685.5
Rho related BTB domain containing 2
chr20_+_64038120 0.33 ENST00000463337.1
chromosome 20 open reading frame 204
chrX_-_134797134 0.33 ENST00000370790.5
ENST00000493333.5
ENST00000611027.2
ENST00000343004.10
ENST00000298090.10
PABIR family member 2
chr2_-_241508568 0.33 ENST00000426941.1
ENST00000316586.9
ENST00000405585.5
ENST00000420551.1
ENST00000429279.5
ENST00000442307.5
serine/threonine kinase 25
chr13_-_52739769 0.33 ENST00000448904.6
ENST00000377962.8
chondromodulin
chr11_-_63563370 0.33 ENST00000255695.2
phospholipase A and acyltransferase 2
chr17_-_4560564 0.32 ENST00000574584.1
ENST00000381550.8
ENST00000301395.7
gamma-glutamyltransferase 6

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0042668 trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164) negative regulation of pro-B cell differentiation(GO:2000974)
0.5 2.2 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.5 1.6 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.5 2.0 GO:0048865 stem cell fate commitment(GO:0048865)
0.3 0.9 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.3 0.9 GO:2000830 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.3 1.5 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.3 1.2 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.3 0.8 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.3 1.1 GO:0009439 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.3 1.1 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.2 1.5 GO:0038016 insulin receptor internalization(GO:0038016)
0.2 0.7 GO:1903384 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.2 0.7 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.2 1.0 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.2 0.4 GO:0090272 negative regulation of fibroblast growth factor production(GO:0090272)
0.2 1.7 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 0.6 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.2 0.5 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.2 0.5 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.2 5.0 GO:0072189 ureter development(GO:0072189)
0.1 0.7 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.1 0.4 GO:0006533 aspartate catabolic process(GO:0006533)
0.1 0.4 GO:0042938 dipeptide transport(GO:0042938)
0.1 0.5 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 0.4 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.4 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.5 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 0.5 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.1 0.7 GO:0050668 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.1 1.8 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.8 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.1 0.3 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.1 0.4 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.1 0.3 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.1 0.3 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 0.4 GO:0006562 proline catabolic process(GO:0006562)
0.1 0.4 GO:0043335 protein unfolding(GO:0043335)
0.1 0.3 GO:0003064 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.1 0.6 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.1 0.5 GO:0032571 response to vitamin K(GO:0032571)
0.1 0.4 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.1 0.3 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.1 0.3 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.6 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.2 GO:2000506 negative regulation of energy homeostasis(GO:2000506)
0.1 0.5 GO:0070560 protein secretion by platelet(GO:0070560)
0.1 0.8 GO:0032328 alanine transport(GO:0032328)
0.1 0.2 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.1 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.1 GO:0002316 follicular B cell differentiation(GO:0002316)
0.1 0.2 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1 1.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 0.8 GO:0036481 intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481)
0.1 0.6 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.1 0.4 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204) cellular lipid biosynthetic process(GO:0097384)
0.1 0.4 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.2 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 0.4 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 0.4 GO:0046061 dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061)
0.1 0.4 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 1.3 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.1 0.4 GO:2000909 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.1 0.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.2 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 2.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 1.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.3 GO:1990539 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.5 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 0.4 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.8 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.0 1.1 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.2 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.2 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 0.9 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.1 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.6 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.3 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.4 GO:0046826 negative regulation of protein export from nucleus(GO:0046826) protein K6-linked ubiquitination(GO:0085020)
0.0 0.5 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.2 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 1.7 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.4 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.3 GO:0032264 IMP salvage(GO:0032264)
0.0 0.4 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.3 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.5 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.7 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.4 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.8 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.3 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.5 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.3 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.2 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.0 0.9 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.5 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 1.0 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.4 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.8 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.4 GO:0032310 prostaglandin secretion(GO:0032310)
0.0 0.3 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.0 GO:0090365 regulation of mRNA modification(GO:0090365)
0.0 0.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.4 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.4 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.4 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.2 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.3 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.4 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.0 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.6 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 1.1 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.9 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.0 0.6 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.4 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.3 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.0 0.2 GO:0006489 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.0 0.5 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.1 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.0 0.1 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.0 0.3 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.4 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.9 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.4 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.1 GO:0001878 response to yeast(GO:0001878)
0.0 0.4 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0 0.4 GO:0010226 response to lithium ion(GO:0010226)
0.0 0.4 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.0 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.5 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 0.1 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.1 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.4 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.4 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 2.6 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 1.1 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.1 GO:0050893 sensory processing(GO:0050893)
0.0 1.1 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.4 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.7 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.2 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 2.4 GO:0007286 spermatid development(GO:0007286)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.1 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.1 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.2 0.6 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2 0.5 GO:0071756 IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
0.1 0.4 GO:0055087 Ski complex(GO:0055087)
0.1 0.4 GO:0044307 dendritic branch(GO:0044307)
0.1 0.5 GO:0031501 mannosyltransferase complex(GO:0031501)
0.1 1.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 0.6 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.0 GO:0097418 neurofibrillary tangle(GO:0097418)
0.1 0.7 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.3 GO:0031523 Myb complex(GO:0031523)
0.1 0.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.9 GO:0030008 TRAPP complex(GO:0030008)
0.1 2.1 GO:0071564 npBAF complex(GO:0071564)
0.1 0.3 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.0 GO:0044393 microspike(GO:0044393)
0.0 0.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.3 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.3 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 1.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.4 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.1 GO:0005602 complement component C1 complex(GO:0005602)
0.0 1.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.4 GO:0034464 BBSome(GO:0034464)
0.0 0.6 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 1.0 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 1.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.5 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.3 GO:0097512 cardiac myofibril(GO:0097512)
0.0 2.6 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.8 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.4 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.6 GO:0031201 SNARE complex(GO:0031201)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.8 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 1.2 GO:0043195 terminal bouton(GO:0043195)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.3 1.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 1.5 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.2 1.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.2 1.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.2 0.6 GO:0047012 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity(GO:0047012)
0.2 1.5 GO:0015235 cobalamin transporter activity(GO:0015235)
0.2 0.5 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.1 0.4 GO:0044713 GTP diphosphatase activity(GO:0036219) 2-hydroxy-adenosine triphosphate pyrophosphatase activity(GO:0044713) 2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity(GO:0044714) ATP diphosphatase activity(GO:0047693)
0.1 0.7 GO:0008518 reduced folate carrier activity(GO:0008518)
0.1 0.5 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 2.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 1.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.4 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
0.1 0.4 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 0.6 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1 0.5 GO:0008241 tripeptidyl-peptidase activity(GO:0008240) peptidyl-dipeptidase activity(GO:0008241) bradykinin receptor binding(GO:0031711) metallodipeptidase activity(GO:0070573)
0.1 0.4 GO:0001512 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.1 1.0 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.4 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.6 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 1.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.4 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.3 GO:0004461 lactose synthase activity(GO:0004461)
0.1 0.7 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 0.4 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 0.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.2 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.4 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.3 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 1.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.4 GO:0004517 nitric-oxide synthase activity(GO:0004517) tetrahydrobiopterin binding(GO:0034617)
0.1 0.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 1.1 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.5 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.5 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 0.2 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 1.1 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.4 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.3 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.6 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 1.0 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.6 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.5 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.4 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.5 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.4 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 1.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 1.6 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.4 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.6 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.2 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.3 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.3 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.9 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 2.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 1.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.2 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.0 0.4 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.7 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 2.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.7 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 2.4 GO:0051087 chaperone binding(GO:0051087)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0010465 neurotrophin p75 receptor binding(GO:0005166) nerve growth factor receptor activity(GO:0010465)
0.0 0.5 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.1 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.1 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.0 0.5 GO:0046961 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.3 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 7.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.2 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.9 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.4 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.0 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.8 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.7 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.1 GO:0008307 structural constituent of muscle(GO:0008307)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.0 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 2.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 2.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 2.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 2.2 PID EPO PATHWAY EPO signaling pathway
0.0 0.8 PID ATM PATHWAY ATM pathway
0.0 1.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.4 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.8 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 2.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.1 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 1.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 3.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.9 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.9 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.8 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.6 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.9 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 1.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.9 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 1.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.6 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS Genes involved in Acetylcholine Binding And Downstream Events
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.6 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.7 REACTOME SIGNALING BY FGFR MUTANTS Genes involved in Signaling by FGFR mutants
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis