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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for HOXA1

Z-value: 0.71

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Transcription factors associated with HOXA1

Gene Symbol Gene ID Gene Info
ENSG00000105991.10 HOXA1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA1hg38_v1_chr7_-_27095972_270960390.262.1e-01Click!

Activity profile of HOXA1 motif

Sorted Z-values of HOXA1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chrX_-_63785510 1.51 ENST00000437457.6
ENST00000374878.5
ENST00000623517.3
Cdc42 guanine nucleotide exchange factor 9
chr16_+_83968244 1.35 ENST00000305202.9
N-terminal EF-hand calcium binding protein 2
chr7_+_80135694 1.22 ENST00000457358.7
G protein subunit alpha i1
chr2_-_75560893 1.16 ENST00000410113.5
ENST00000393913.8
eva-1 homolog A, regulator of programmed cell death
chr6_-_13487593 1.16 ENST00000379287.4
ENST00000603223.1
glucose-fructose oxidoreductase domain containing 1
chr1_-_91886144 1.08 ENST00000212355.9
transforming growth factor beta receptor 3
chr4_-_137532452 1.07 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
protocadherin 18
chr7_-_101165114 1.03 ENST00000445482.2
VGF nerve growth factor inducible
chr11_-_69819410 1.01 ENST00000334134.4
fibroblast growth factor 3
chr2_-_189580773 1.01 ENST00000261024.7
solute carrier family 40 member 1
chr22_-_30470577 0.97 ENST00000435069.1
ENST00000540910.5
SEC14 like lipid binding 3
chr1_+_18630839 0.89 ENST00000420770.7
paired box 7
chr1_+_12063285 0.82 ENST00000263932.7
TNF receptor superfamily member 8
chr3_+_196639684 0.79 ENST00000328557.5
negative regulator of reactive oxygen species
chr6_+_15248855 0.77 ENST00000397311.4
jumonji and AT-rich interaction domain containing 2
chr6_+_130366281 0.76 ENST00000617887.4
transmembrane protein 200A
chr15_-_52295792 0.74 ENST00000261839.12
myosin VC
chr7_-_101165558 0.72 ENST00000611537.1
ENST00000249330.3
VGF nerve growth factor inducible
chr6_+_32038382 0.70 ENST00000478281.5
ENST00000471671.4
ENST00000435122.3
ENST00000644719.2
cytochrome P450 family 21 subfamily A member 2
chrX_-_10677720 0.70 ENST00000453318.6
midline 1
chr9_-_94640130 0.68 ENST00000414122.1
fructose-bisphosphatase 1
chr13_-_77919390 0.67 ENST00000475537.2
ENST00000646605.1
endothelin receptor type B
chr5_+_36151989 0.61 ENST00000274254.9
S-phase kinase associated protein 2
chr14_-_106374129 0.61 ENST00000390616.2
immunoglobulin heavy variable 4-34
chr12_+_12725897 0.58 ENST00000326765.10
apolipoprotein L domain containing 1
chr1_+_65264694 0.57 ENST00000263441.11
ENST00000395325.7
DnaJ heat shock protein family (Hsp40) member C6
chr20_-_25058115 0.56 ENST00000323482.9
acyl-CoA synthetase short chain family member 1
chr19_-_11339573 0.55 ENST00000222120.8
RAB3D, member RAS oncogene family
chr1_+_2073986 0.54 ENST00000461106.6
protein kinase C zeta
chr9_-_10612966 0.54 ENST00000381196.9
protein tyrosine phosphatase receptor type D
chr15_+_94355956 0.54 ENST00000557742.1
multiple C2 and transmembrane domain containing 2
chr20_+_36154630 0.52 ENST00000338074.7
ENST00000636016.2
ENST00000373945.5
erythrocyte membrane protein band 4.1 like 1
chr15_+_47717344 0.52 ENST00000558816.5
ENST00000536845.7
semaphorin 6D
chr19_-_49020523 0.52 ENST00000637680.1
novel protein
chr17_-_48613468 0.52 ENST00000498634.2
homeobox B8
chr17_+_41819201 0.51 ENST00000455106.1
FKBP prolyl isomerase 10
chr5_-_137736066 0.50 ENST00000309755.9
kelch like family member 3
chr12_-_95116967 0.50 ENST00000551521.5
FYVE, RhoGEF and PH domain containing 6
chr19_+_16324817 0.49 ENST00000248071.6
ENST00000592003.1
Kruppel like factor 2
chr5_+_36152077 0.49 ENST00000546211.6
ENST00000620197.5
ENST00000678270.1
ENST00000679015.1
ENST00000678580.1
ENST00000274255.11
ENST00000508514.5
S-phase kinase associated protein 2
chr2_+_24049705 0.48 ENST00000380986.9
ENST00000452109.1
FKBP prolyl isomerase 1B
chr11_-_5441514 0.48 ENST00000380211.1
olfactory receptor family 51 subfamily I member 1
chr7_-_120857124 0.45 ENST00000441017.5
ENST00000424710.5
ENST00000433758.5
tetraspanin 12
chr6_+_17393576 0.44 ENST00000229922.7
ENST00000611958.4
cyclase associated actin cytoskeleton regulatory protein 2
chr12_-_14885845 0.44 ENST00000539261.6
ENST00000228938.5
matrix Gla protein
chr8_-_27611424 0.43 ENST00000405140.7
clusterin
chr6_+_17393505 0.43 ENST00000616440.4
cyclase associated actin cytoskeleton regulatory protein 2
chr8_-_27611325 0.42 ENST00000523500.5
clusterin
chr6_+_89562308 0.42 ENST00000522441.5
ankyrin repeat domain 6
chr11_+_5488685 0.41 ENST00000322641.5
olfactory receptor family 52 subfamily D member 1
chr19_+_1908258 0.40 ENST00000411971.5
ENST00000588907.2
secretory carrier membrane protein 4
chr5_-_20575850 0.40 ENST00000507958.5
cadherin 18
chr19_-_40226682 0.40 ENST00000430325.7
ENST00000599263.6
cyclin P
chr6_-_31684040 0.39 ENST00000375863.7
lymphocyte antigen 6 family member G5C
chr17_+_7855055 0.39 ENST00000574668.1
ENST00000301599.7
transmembrane protein 88
chr3_+_111674654 0.39 ENST00000636933.1
ENST00000393934.7
ENST00000477665.2
phosphatidylinositol specific phospholipase C X domain containing 2
chr17_-_3595831 0.38 ENST00000399759.7
transient receptor potential cation channel subfamily V member 1
chr3_-_129893551 0.38 ENST00000505616.5
ENST00000426664.6
ENST00000648771.1
ENST00000393238.8
transmembrane and coiled-coil domain family 1
chr9_+_122519141 0.38 ENST00000340750.1
olfactory receptor family 1 subfamily J member 4
chr10_-_63269057 0.37 ENST00000542921.5
jumonji domain containing 1C
chr11_-_2140967 0.37 ENST00000381389.5
insulin like growth factor 2
chr19_+_840991 0.35 ENST00000234347.10
proteinase 3
chr8_+_2045058 0.34 ENST00000523438.1
myomesin 2
chr5_-_42825884 0.33 ENST00000506577.5
selenoprotein P
chr12_+_124993633 0.33 ENST00000341446.9
ENST00000671775.2
BRI3 binding protein
chr5_-_36151853 0.33 ENST00000296603.5
LMBR1 domain containing 2
chr2_-_44361555 0.33 ENST00000409957.5
prolyl endopeptidase like
chr9_-_94640248 0.33 ENST00000415431.5
fructose-bisphosphatase 1
chr1_+_202203721 0.33 ENST00000255432.11
leucine rich repeat containing G protein-coupled receptor 6
chr10_+_119104075 0.33 ENST00000472379.2
ENST00000361432.3
ENST00000648560.1
DENN domain containing 10
chr19_-_42423100 0.32 ENST00000597001.1
lipase E, hormone sensitive type
chr3_+_196639735 0.31 ENST00000426755.5
phosphatidylinositol glycan anchor biosynthesis class X
chr7_+_94509793 0.31 ENST00000297273.9
CAS1 domain containing 1
chr3_-_49813880 0.31 ENST00000333486.4
ubiquitin like modifier activating enzyme 7
chr14_-_20305932 0.30 ENST00000258821.8
ENST00000553828.1
tetratricopeptide repeat domain 5
chr2_+_24049673 0.30 ENST00000380991.8
FKBP prolyl isomerase 1B
chr1_-_24143112 0.30 ENST00000270800.2
interleukin 22 receptor subunit alpha 1
chr7_-_117323041 0.30 ENST00000491214.1
ENST00000265441.8
Wnt family member 2
chr17_+_45161864 0.30 ENST00000589230.6
ENST00000591576.5
ENST00000591070.6
ENST00000592695.1
HEXIM P-TEFb complex subunit 2
chr13_+_91398613 0.30 ENST00000377067.9
glypican 5
chr2_-_69961624 0.29 ENST00000320256.6
aspartic peptidase retroviral like 1
chr1_-_13201409 0.29 ENST00000625019.3
PRAME family member 13
chr1_-_182672232 0.28 ENST00000508450.5
regulator of G protein signaling 8
chr2_+_230864921 0.28 ENST00000326427.11
ENST00000335005.10
ENST00000326407.10
integral membrane protein 2C
chr2_+_64988469 0.28 ENST00000531327.5
solute carrier family 1 member 4
chr8_+_42338477 0.28 ENST00000518925.5
ENST00000265421.9
DNA polymerase beta
chr3_+_159839847 0.28 ENST00000445224.6
schwannomin interacting protein 1
chr19_+_17420029 0.27 ENST00000317040.12
ENST00000529939.5
ENST00000528515.5
ENST00000543795.5
multivesicular body subunit 12A
chr7_+_105014176 0.27 ENST00000257745.8
ENST00000311117.8
ENST00000478990.5
ENST00000495267.5
ENST00000476671.5
lysine methyltransferase 2E (inactive)
chr16_-_28471175 0.27 ENST00000435324.3
nuclear pore complex interacting protein family member B7
chr6_+_17393607 0.27 ENST00000489374.5
ENST00000378990.6
cyclase associated actin cytoskeleton regulatory protein 2
chr19_+_13764502 0.27 ENST00000040663.8
ENST00000319545.12
methylthioribose-1-phosphate isomerase 1
chr2_-_43676406 0.27 ENST00000475092.4
C1GALT1 specific chaperone 1 like
chr22_-_50261543 0.26 ENST00000395778.3
ENST00000215659.13
mitogen-activated protein kinase 12
chr14_+_24232921 0.26 ENST00000557854.5
ENST00000399440.7
ENST00000559104.5
ENST00000456667.7
guanosine monophosphate reductase 2
chr20_+_9514562 0.25 ENST00000246070.3
lysosomal associated membrane protein family member 5
chr1_+_162632454 0.25 ENST00000367921.8
ENST00000367922.7
discoidin domain receptor tyrosine kinase 2
chr1_-_44674402 0.25 ENST00000420706.1
ENST00000372235.7
ENST00000372242.7
ENST00000372243.7
ENST00000372244.3
ENST00000372237.8
transmembrane protein 53
chr1_+_43300971 0.25 ENST00000372476.8
ENST00000538015.1
tyrosine kinase with immunoglobulin like and EGF like domains 1
chr2_-_153478753 0.25 ENST00000325926.4
reprimo, TP53 dependent G2 arrest mediator homolog
chr3_+_159852933 0.24 ENST00000482804.1
schwannomin interacting protein 1
chr16_-_28470905 0.24 ENST00000652214.1
nuclear pore complex interacting protein family member B7
chr8_-_27605271 0.24 ENST00000522098.1
clusterin
chr2_+_180980347 0.24 ENST00000602959.5
ENST00000602479.5
ENST00000392415.6
ENST00000602291.5
ubiquitin conjugating enzyme E2 E3
chr17_-_76308271 0.23 ENST00000680821.2
glutamine rich 2
chr19_+_54630960 0.23 ENST00000396317.5
ENST00000396315.5
leukocyte immunoglobulin like receptor B1
chr2_-_169824851 0.23 ENST00000410097.5
ENST00000308099.7
ENST00000409837.5
ENST00000260953.10
ENST00000538491.1
ENST00000409965.5
ENST00000392640.6
methyltransferase like 5
chr9_-_5304713 0.23 ENST00000381627.4
relaxin 2
chr8_-_65634202 0.23 ENST00000458464.3
armadillo repeat containing 1
chr16_+_30378312 0.22 ENST00000528032.5
ENST00000622647.3
zinc finger protein 48
chr2_-_169824814 0.22 ENST00000409340.5
methyltransferase like 5
chr12_+_48183602 0.22 ENST00000316554.5
coiled-coil domain containing 184
chr15_-_93073111 0.22 ENST00000557420.1
ENST00000542321.6
repulsive guidance molecule BMP co-receptor a
chrX_+_135309480 0.22 ENST00000635820.1
embryonic testis differentiation homolog C
chr5_+_108747879 0.22 ENST00000281092.9
FER tyrosine kinase
chr13_-_20161038 0.22 ENST00000241125.4
gap junction protein alpha 3
chr22_-_50261711 0.21 ENST00000622558.4
mitogen-activated protein kinase 12
chr16_+_15502266 0.21 ENST00000452191.6
bMERB domain containing 1
chr8_-_65634138 0.21 ENST00000518908.5
ENST00000276569.8
ENST00000519352.1
armadillo repeat containing 1
chr5_+_140834230 0.21 ENST00000356878.5
ENST00000525929.2
protocadherin alpha 7
chr8_+_67952028 0.21 ENST00000288368.5
phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2
chr8_+_97775829 0.21 ENST00000517924.5
lysosomal protein transmembrane 4 beta
chr1_-_151347234 0.21 ENST00000290524.8
ENST00000452671.7
ENST00000437327.5
ENST00000368870.6
regulatory factor X5
chr7_+_139829242 0.20 ENST00000455353.6
ENST00000458722.6
ENST00000448866.7
ENST00000411653.6
thromboxane A synthase 1
chr10_-_87863533 0.20 ENST00000445946.5
killin, p53 regulated DNA replication inhibitor
chr4_+_70721953 0.20 ENST00000381006.8
ENST00000226328.8
RUN and FYVE domain containing 3
chr16_-_66550112 0.20 ENST00000544898.6
ENST00000620035.5
ENST00000545043.6
thymidine kinase 2
chr1_-_217631034 0.20 ENST00000366934.3
ENST00000366935.8
G-patch domain containing 2
chr20_+_45408276 0.20 ENST00000372710.5
ENST00000443296.1
dysbindin domain containing 2
chr15_+_81299416 0.20 ENST00000558332.3
interleukin 16
chr7_-_44141074 0.20 ENST00000457314.5
ENST00000447951.1
ENST00000431007.1
myosin light chain 7
chr18_-_76495191 0.20 ENST00000443185.7
zinc finger protein 516
chr1_-_13347134 0.19 ENST00000334600.7
PRAME family member 14
chr20_-_23421409 0.19 ENST00000377026.4
ENST00000398425.7
ENST00000432543.6
ENST00000617876.4
NSF attachment protein beta
chr19_-_38878247 0.19 ENST00000591812.2
Ras and Rab interactor like
chr2_+_1484663 0.19 ENST00000446278.5
ENST00000469607.3
thyroid peroxidase
chr6_-_168319762 0.19 ENST00000366795.4
dishevelled binding antagonist of beta catenin 2
chr8_+_97775775 0.19 ENST00000521545.7
lysosomal protein transmembrane 4 beta
chr6_-_41154326 0.19 ENST00000426005.6
ENST00000437044.2
ENST00000373127.8
triggering receptor expressed on myeloid cells like 1
chr15_-_22185402 0.18 ENST00000557788.2
immunoglobulin heavy variable 4/OR15-8 (non-functional)
chr16_+_29662923 0.18 ENST00000395389.2
sialophorin
chr20_+_2692736 0.18 ENST00000380648.9
ENST00000497450.5
EBF family member 4
chr17_-_44023106 0.18 ENST00000585950.5
ENST00000592127.5
ENST00000589334.5
transmembrane protein 101
chr13_+_35476740 0.18 ENST00000537702.5
neurobeachin
chr6_-_31592992 0.18 ENST00000340027.10
natural cytotoxicity triggering receptor 3
chr4_-_151325488 0.17 ENST00000604030.7
SH3 domain containing 19
chr2_-_152098810 0.17 ENST00000636442.1
ENST00000638005.1
calcium voltage-gated channel auxiliary subunit beta 4
chr1_+_17308194 0.17 ENST00000375453.5
ENST00000375448.4
peptidyl arginine deiminase 4
chr11_+_18266254 0.17 ENST00000532858.5
ENST00000649195.1
ENST00000356524.9
ENST00000405158.2
serum amyloid A1
chr10_-_33334382 0.17 ENST00000374823.9
ENST00000374821.9
ENST00000374816.7
neuropilin 1
chr5_+_134526176 0.17 ENST00000681820.1
ENST00000512386.6
ENST00000612830.2
jade family PHD finger 2
chr1_-_19980416 0.17 ENST00000375111.7
phospholipase A2 group IIA
chr12_-_110468222 0.16 ENST00000228827.8
ENST00000537466.6
ENST00000550974.1
GPN-loop GTPase 3
chr19_-_38256513 0.16 ENST00000347262.8
ENST00000591585.1
protein phosphatase 1 regulatory inhibitor subunit 14A
chrX_+_54808359 0.16 ENST00000375058.5
ENST00000375060.5
MAGE family member D2
chr11_+_63938971 0.16 ENST00000539656.5
ENST00000377793.9
N-alpha-acetyltransferase 40, NatD catalytic subunit
chr9_-_83956677 0.16 ENST00000376344.8
chromosome 9 open reading frame 64
chr12_+_63779894 0.16 ENST00000261234.11
ribitol xylosyltransferase 1
chr16_+_29663219 0.16 ENST00000436527.5
ENST00000360121.4
ENST00000652691.1
ENST00000449759.2
sialophorin
quinolinate phosphoribosyltransferase
chr12_-_49094792 0.16 ENST00000649637.2
desert hedgehog signaling molecule
chr17_-_59151794 0.15 ENST00000584089.1
spindle and kinetochore associated complex subunit 2
chr7_+_33904911 0.15 ENST00000297161.6
BMP binding endothelial regulator
chr11_+_125904467 0.15 ENST00000263576.11
ENST00000530414.5
ENST00000530129.6
DEAD-box helicase 25
chr1_+_12063357 0.15 ENST00000417814.3
TNF receptor superfamily member 8
chr13_-_37105664 0.15 ENST00000379800.4
casein kinase 1 alpha 1 like
chr14_-_68979436 0.15 ENST00000193403.10
actinin alpha 1
chr6_-_168319691 0.15 ENST00000610183.1
ENST00000607983.1
dishevelled binding antagonist of beta catenin 2
chr17_-_3292600 0.15 ENST00000615105.1
olfactory receptor family 3 subfamily A member 1
chr14_+_24130659 0.15 ENST00000267426.6
fat storage inducing transmembrane protein 1
chr2_+_237692290 0.15 ENST00000420665.5
ENST00000392000.4
LRR binding FLII interacting protein 1
chr16_+_28292485 0.15 ENST00000341901.5
SH3 domain binding kinase 1
chr1_-_110519175 0.14 ENST00000369771.4
potassium voltage-gated channel subfamily A member 10
chrX_+_135520616 0.14 ENST00000370752.4
ENST00000639893.2
integrator complex subunit 6 like
chr15_+_73443149 0.14 ENST00000560581.1
ENST00000331090.11
REC114 meiotic recombination protein
chr6_-_31721679 0.14 ENST00000495859.1
ENST00000375819.3
lymphocyte antigen 6 family member G6C
chr12_-_84912705 0.14 ENST00000679933.1
ENST00000680260.1
ENST00000551010.2
ENST00000679453.1
ENST00000681281.1
solute carrier family 6 member 15
chr17_-_8156320 0.14 ENST00000584202.1
ENST00000354903.9
ENST00000577253.5
period circadian regulator 1
chr17_+_42780592 0.14 ENST00000246914.10
WNK lysine deficient protein kinase 4
chr1_+_228208054 0.14 ENST00000284548.16
ENST00000422127.5
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr12_-_54984667 0.14 ENST00000524668.5
ENST00000533607.1
ENST00000449076.6
thymocyte expressed, positive selection associated 1
chrX_+_54808334 0.14 ENST00000218439.8
MAGE family member D2
chr6_-_31592952 0.13 ENST00000376073.8
ENST00000376072.7
natural cytotoxicity triggering receptor 3
chr8_-_96235533 0.13 ENST00000518406.5
ENST00000287022.10
ENST00000523920.1
ubiquinol-cytochrome c reductase binding protein
chr2_+_70978380 0.13 ENST00000272421.10
ENST00000441349.5
ENST00000457410.5
ankyrin repeat domain 53
chrM_+_4467 0.13 ENST00000361453.3
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2
chr4_+_153257339 0.13 ENST00000676374.1
ENST00000676196.1
ENST00000674935.1
ENST00000674769.1
ENST00000674896.1
ENST00000676191.1
ENST00000675312.1
ENST00000675456.1
ENST00000674847.1
ENST00000675977.1
ENST00000676264.1
ENST00000674726.1
ENST00000676252.1
ENST00000674730.1
ENST00000675738.1
ENST00000482578.3
tripartite motif containing 2
chr13_+_111114550 0.13 ENST00000317133.9
Rho guanine nucleotide exchange factor 7
chr2_-_70835808 0.13 ENST00000410009.5
CD207 molecule
chrX_+_37780049 0.13 ENST00000378588.5
cytochrome b-245 beta chain
chr19_-_15898057 0.12 ENST00000011989.11
ENST00000221700.11
cytochrome P450 family 4 subfamily F member 2
chr2_+_44168866 0.12 ENST00000282412.9
ENST00000409432.7
ENST00000378551.6
ENST00000345249.8
protein phosphatase, Mg2+/Mn2+ dependent 1B
chr11_+_26188836 0.12 ENST00000672621.1
anoctamin 3
chr14_+_24310170 0.12 ENST00000530080.1
leukotriene B4 receptor 2
chr19_-_54242751 0.12 ENST00000245621.6
ENST00000396365.6
leukocyte immunoglobulin like receptor A6
chr3_+_98497681 0.12 ENST00000427338.3
olfactory receptor family 5 subfamily K member 2
chr3_-_146544701 0.12 ENST00000487389.5
phospholipid scramblase 1
chr4_+_81030700 0.12 ENST00000282701.4
bone morphogenetic protein 3
chr15_+_75336078 0.12 ENST00000567377.5
ENST00000562789.5
ENST00000568301.1
COMM domain containing 4
chr8_-_78805306 0.12 ENST00000639719.1
ENST00000263851.9
interleukin 7
chr1_+_161153968 0.12 ENST00000368003.6
ubiquitin-fold modifier conjugating enzyme 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:1904021 negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.3 1.0 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.3 1.0 GO:0045556 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.3 0.9 GO:0014813 skeletal muscle satellite cell commitment(GO:0014813)
0.3 1.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.3 1.0 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.2 1.1 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.2 0.6 GO:0019427 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate biosynthetic process(GO:0019542)
0.2 1.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.7 GO:0035645 enteric smooth muscle cell differentiation(GO:0035645)
0.1 0.5 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.5 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.1 0.3 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.1 0.5 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 0.4 GO:0050960 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.1 0.5 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 1.2 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.3 GO:0072061 inner medullary collecting duct development(GO:0072061) negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.8 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.1 0.6 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.3 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.1 0.3 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.1 0.1 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.1 0.2 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.2 GO:0035548 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.1 0.2 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.1 0.5 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.2 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 1.7 GO:0002021 response to dietary excess(GO:0002021)
0.1 0.3 GO:0019075 virus maturation(GO:0019075)
0.1 0.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.3 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 0.3 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.2 GO:1990523 bone regeneration(GO:1990523)
0.0 0.6 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.7 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.8 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.3 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.3 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.2 GO:0061552 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0 0.1 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.3 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.7 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 0.3 GO:0060424 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718) positive regulation of meiosis I(GO:0060903)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.2 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.3 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.5 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.1 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.1 GO:0035261 external genitalia morphogenesis(GO:0035261)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.3 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.1 GO:0050883 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.1 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.1 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.1 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.5 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.1 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.0 0.1 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.7 GO:0055026 negative regulation of cardiac muscle tissue development(GO:0055026)
0.0 0.3 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.4 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.3 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.4 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.1 GO:1990167 protein K6-linked deubiquitination(GO:0044313) protein K27-linked deubiquitination(GO:1990167)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.1 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.5 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.6 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.1 GO:0061591 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.5 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.0 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.0 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.0 0.2 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.2 GO:0030238 male sex determination(GO:0030238) Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:0061143 alveolar primary septum development(GO:0061143) paramesonephric duct development(GO:0061205)
0.0 0.5 GO:0007190 activation of adenylate cyclase activity(GO:0007190)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 1.1 GO:0097418 neurofibrillary tangle(GO:0097418)
0.1 0.3 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.5 GO:0043203 axon hillock(GO:0043203)
0.0 0.1 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.0 0.1 GO:0032116 SMC loading complex(GO:0032116)
0.0 0.3 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.5 GO:0042588 zymogen granule(GO:0042588)
0.0 1.2 GO:0099738 cell cortex region(GO:0099738)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.3 GO:1990909 Wnt signalosome(GO:1990909)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 0.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.3 1.0 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.2 0.8 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 0.6 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 1.0 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 0.9 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 0.3 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 1.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 1.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.2 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 1.0 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 1.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.3 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.2 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.1 0.4 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.1 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.3 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 1.1 GO:0051787 misfolded protein binding(GO:0051787)
0.0 1.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:0097259 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.3 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.2 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.2 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.3 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:1902271 D3 vitamins binding(GO:1902271)
0.0 0.2 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.3 GO:0008430 selenium binding(GO:0008430)
0.0 0.3 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.1 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.8 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.6 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.2 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.9 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.5 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0004096 catalase activity(GO:0004096)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.3 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.7 GO:0030546 receptor activator activity(GO:0030546)
0.0 0.2 GO:0005113 patched binding(GO:0005113)
0.0 0.0 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.1 PID MYC PATHWAY C-MYC pathway
0.0 1.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.7 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.4 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 1.0 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.8 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.8 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 1.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.1 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.8 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.5 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway