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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for HOXA10_HOXB9

Z-value: 0.45

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Transcription factors associated with HOXA10_HOXB9

Gene Symbol Gene ID Gene Info
HOXA10
ENSG00000253293.5 HOXA10
HOXB9
ENSG00000170689.10 HOXB9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA10hg38_v1_chr7_-_27174274_27174335,
hg38_v1_chr7_-_27174253_27174267		-0.452.3e-02Click!
HOXB9hg38_v1_chr17_-_48626325_486263790.067.6e-01Click!

Activity profile of HOXA10_HOXB9 motif

Sorted Z-values of HOXA10_HOXB9 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA10_HOXB9

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr15_+_67125707 1.33 ENST00000540846.6
SMAD3
SMAD family member 3
chr6_+_32844789 1.29 ENST00000414474.5
PSMB9
proteasome 20S subunit beta 9
chr15_-_55249029 1.08 ENST00000566877.5
RAB27A
RAB27A, member RAS oncogene family
chr18_-_5396265 0.97 ENST00000579951.2
EPB41L3
erythrocyte membrane protein band 4.1 like 3
chr4_-_76036060 0.91 ENST00000306621.8
CXCL11
C-X-C motif chemokine ligand 11
chr1_-_120054225 0.90 ENST00000602566.6
NOTCH2
notch receptor 2
chr4_+_70050431 0.72 ENST00000511674.5
ENST00000246896.8
HTN1
histatin 1
chr1_+_244352627 0.71 ENST00000366537.5
ENST00000308105.5
C1orf100
chromosome 1 open reading frame 100
chr5_+_98773651 0.56 ENST00000513185.3
RGMB
repulsive guidance molecule BMP co-receptor b
chr1_+_206635521 0.55 ENST00000367109.8
DYRK3
dual specificity tyrosine phosphorylation regulated kinase 3
chr7_-_41703062 0.52 ENST00000242208.5
INHBA
inhibin subunit beta A
chr18_+_58196736 0.51 ENST00000675221.1
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr11_+_111245725 0.49 ENST00000280325.7
C11orf53
chromosome 11 open reading frame 53
chr10_+_89392546 0.47 ENST00000546318.2
ENST00000371804.4
IFIT1
interferon induced protein with tetratricopeptide repeats 1
chr11_+_55635113 0.46 ENST00000641760.1
OR4P4
olfactory receptor family 4 subfamily P member 4
chr4_+_95051671 0.45 ENST00000440890.7
BMPR1B
bone morphogenetic protein receptor type 1B
chr5_-_58999885 0.44 ENST00000317118.12
PDE4D
phosphodiesterase 4D
chr6_-_154430495 0.38 ENST00000424998.3
CNKSR3
CNKSR family member 3
chr6_+_29301701 0.37 ENST00000641895.1
OR14J1
olfactory receptor family 14 subfamily J member 1
chr11_-_55936400 0.34 ENST00000301532.3
OR5I1
olfactory receptor family 5 subfamily I member 1
chr2_+_102311502 0.33 ENST00000404917.6
ENST00000410040.5
IL1RL1
IL18R1
interleukin 1 receptor like 1
interleukin 18 receptor 1
chr2_-_216013582 0.30 ENST00000620139.4
MREG
melanoregulin
chr2_-_189179754 0.29 ENST00000374866.9
ENST00000618828.1
COL5A2
collagen type V alpha 2 chain
chr19_+_47994625 0.29 ENST00000339841.7
ELSPBP1
epididymal sperm binding protein 1
chr10_-_127892930 0.29 ENST00000368671.4
CLRN3
clarin 3
chr19_+_47994696 0.28 ENST00000596043.5
ENST00000597519.5
ELSPBP1
epididymal sperm binding protein 1
chr11_-_105035113 0.26 ENST00000526568.5
ENST00000531166.5
ENST00000534497.5
ENST00000527979.5
ENST00000533400.6
ENST00000528974.1
ENST00000525825.5
ENST00000353247.9
ENST00000446369.5
ENST00000436863.7
CASP1
caspase 1
chr12_+_69825221 0.26 ENST00000552032.7
MYRFL
myelin regulatory factor like
chr11_-_5154757 0.26 ENST00000380367.3
OR52A1
olfactory receptor family 52 subfamily A member 1
chr17_-_65561137 0.25 ENST00000580513.1
AXIN2
axin 2
chr22_-_37844308 0.25 ENST00000411961.6
ENST00000434930.1
ENST00000215941.9
ANKRD54
ankyrin repeat domain 54
chr15_+_66386902 0.23 ENST00000307102.10
MAP2K1
mitogen-activated protein kinase kinase 1
chr5_+_68290637 0.23 ENST00000336483.9
PIK3R1
phosphoinositide-3-kinase regulatory subunit 1
chr3_+_101827982 0.23 ENST00000461724.5
ENST00000483180.5
ENST00000394054.6
NFKBIZ
NFKB inhibitor zeta
chr15_+_40594001 0.22 ENST00000346991.9
ENST00000528975.5
KNL1
kinetochore scaffold 1
chr10_-_72088533 0.22 ENST00000373109.7
SPOCK2
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2
chr4_+_71062642 0.21 ENST00000649996.1
SLC4A4
solute carrier family 4 member 4
chr12_+_69825273 0.21 ENST00000547771.6
MYRFL
myelin regulatory factor like
chr3_+_138621225 0.21 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr4_+_94974984 0.21 ENST00000672698.1
BMPR1B
bone morphogenetic protein receptor type 1B
chr6_-_83193882 0.20 ENST00000506587.5
ENST00000507554.1
PGM3
phosphoglucomutase 3
chr17_-_10549652 0.20 ENST00000245503.10
MYH2
myosin heavy chain 2
chr1_-_48776811 0.19 ENST00000371833.4
BEND5
BEN domain containing 5
chr9_-_130939205 0.19 ENST00000372338.9
FIBCD1
fibrinogen C domain containing 1
chr6_+_158312459 0.19 ENST00000367097.8
TULP4
TUB like protein 4
chr12_+_54498766 0.19 ENST00000545638.2
NCKAP1L
NCK associated protein 1 like
chr3_-_108953870 0.19 ENST00000261047.8
GUCA1C
guanylate cyclase activator 1C
chr2_+_161136901 0.19 ENST00000259075.6
ENST00000432002.5
TANK
TRAF family member associated NFKB activator
chr12_-_21775581 0.19 ENST00000537950.1
ENST00000665145.1
KCNJ8
potassium inwardly rectifying channel subfamily J member 8
chr22_-_32255344 0.19 ENST00000266086.6
SLC5A4
solute carrier family 5 member 4
chr8_-_103501890 0.19 ENST00000649416.1
ENSG00000285982.1
novel protein
chr4_-_71784046 0.19 ENST00000513476.5
ENST00000273951.13
GC
GC vitamin D binding protein
chr5_+_136160986 0.18 ENST00000507637.1
SMAD5
SMAD family member 5
chr4_-_68670648 0.18 ENST00000338206.6
UGT2B15
UDP glucuronosyltransferase family 2 member B15
chr4_+_70397931 0.18 ENST00000399575.7
OPRPN
opiorphin prepropeptide
chr5_-_161546671 0.18 ENST00000517547.5
GABRB2
gamma-aminobutyric acid type A receptor subunit beta2
chr15_-_101277287 0.18 ENST00000528346.1
ENST00000531964.5
ENST00000398226.7
ENST00000526049.6
SELENOS
selenoprotein S
chr5_-_161546970 0.17 ENST00000675303.1
GABRB2
gamma-aminobutyric acid type A receptor subunit beta2
chr10_+_84173793 0.17 ENST00000372126.4
C10orf99
chromosome 10 open reading frame 99
chr21_+_34364003 0.17 ENST00000290310.4
KCNE2
potassium voltage-gated channel subfamily E regulatory subunit 2
chr17_-_10549612 0.17 ENST00000532183.6
ENST00000397183.6
ENST00000420805.1
MYH2
myosin heavy chain 2
chr18_+_58341038 0.17 ENST00000679791.1
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr7_-_143408848 0.17 ENST00000275815.4
EPHA1
EPH receptor A1
chr21_+_42653585 0.17 ENST00000291539.11
PDE9A
phosphodiesterase 9A
chr2_+_219279330 0.17 ENST00000425450.5
ENST00000392086.8
ENST00000421532.5
ENST00000336576.10
DNAJB2
DnaJ heat shock protein family (Hsp40) member B2
chr3_-_50338226 0.16 ENST00000395126.7
RASSF1
Ras association domain family member 1
chr4_+_70383123 0.16 ENST00000304915.8
SMR3B
submaxillary gland androgen regulated protein 3B
chr15_-_58279245 0.16 ENST00000558231.5
ALDH1A2
aldehyde dehydrogenase 1 family member A2
chr19_+_3185911 0.16 ENST00000246117.9
ENST00000588428.5
NCLN
nicalin
chr1_-_161238085 0.15 ENST00000512372.5
ENST00000437437.6
ENST00000412844.6
ENST00000428574.6
ENST00000442691.6
ENST00000505005.5
ENST00000508740.5
ENST00000367981.7
ENST00000502985.5
ENST00000504010.5
ENST00000508387.5
ENST00000511676.5
ENST00000511748.5
ENST00000511944.5
ENST00000515621.5
ENST00000367984.8
ENST00000367985.7
NR1I3
nuclear receptor subfamily 1 group I member 3
chr12_-_62935117 0.15 ENST00000228705.7
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent 1H
chr8_+_131939865 0.15 ENST00000520362.5
ENST00000519656.1
EFR3A
EFR3 homolog A
chr9_+_127264740 0.14 ENST00000373387.9
GARNL3
GTPase activating Rap/RanGAP domain like 3
chr9_+_94084458 0.14 ENST00000620992.5
ENST00000288976.3
PTPDC1
protein tyrosine phosphatase domain containing 1
chr5_-_16738341 0.14 ENST00000515803.5
MYO10
myosin X
chr15_-_55917080 0.14 ENST00000506154.1
NEDD4
NEDD4 E3 ubiquitin protein ligase
chr2_-_164773733 0.13 ENST00000480873.1
COBLL1
cordon-bleu WH2 repeat protein like 1
chr3_-_108953762 0.13 ENST00000393963.7
ENST00000471108.1
GUCA1C
guanylate cyclase activator 1C
chr20_-_7940444 0.13 ENST00000378789.4
HAO1
hydroxyacid oxidase 1
chr17_-_10549694 0.13 ENST00000622564.4
MYH2
myosin heavy chain 2
chr11_+_72189528 0.13 ENST00000312293.9
FOLR1
folate receptor alpha
chr15_+_40594241 0.13 ENST00000532056.5
ENST00000527044.5
ENST00000399668.7
KNL1
kinetochore scaffold 1
chr15_-_83283449 0.13 ENST00000569704.2
BNC1
basonuclin 1
chr18_-_47035621 0.13 ENST00000332567.6
ELOA2
elongin A2
chr14_+_22168387 0.13 ENST00000557168.1
TRAV30
T cell receptor alpha variable 30
chr2_-_68952880 0.13 ENST00000481498.1
ENST00000328895.9
GKN2
gastrokine 2
chr11_+_72189659 0.13 ENST00000393681.6
FOLR1
folate receptor alpha
chr1_+_192158448 0.12 ENST00000367460.4
RGS18
regulator of G protein signaling 18
chr20_-_8019744 0.12 ENST00000246024.7
TMX4
thioredoxin related transmembrane protein 4
chr1_-_161238163 0.12 ENST00000367982.8
NR1I3
nuclear receptor subfamily 1 group I member 3
chr1_-_86383078 0.12 ENST00000460698.6
ODF2L
outer dense fiber of sperm tails 2 like
chr1_-_161238196 0.12 ENST00000367983.9
ENST00000506209.5
ENST00000367980.6
ENST00000628566.2
NR1I3
nuclear receptor subfamily 1 group I member 3
chr4_+_154563003 0.12 ENST00000302068.9
ENST00000509493.1
FGB
fibrinogen beta chain
chr1_-_220089818 0.12 ENST00000498791.6
ENST00000480959.6
BPNT1
3'(2'), 5'-bisphosphate nucleotidase 1
chr7_-_78771265 0.12 ENST00000630991.2
ENST00000629359.2
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr12_-_81598332 0.12 ENST00000443686.7
PPFIA2
PTPRF interacting protein alpha 2
chr1_+_22052627 0.12 ENST00000400259.5
ENST00000344548.7
ENST00000315554.13
ENST00000656825.1
ENST00000651171.1
ENST00000652582.1
ENST00000667384.1
CDC42
cell division cycle 42
chr9_-_101435760 0.11 ENST00000647789.2
ENST00000616752.1
ALDOB
aldolase, fructose-bisphosphate B
chr2_+_9961165 0.11 ENST00000405379.6
GRHL1
grainyhead like transcription factor 1
chr1_-_7853054 0.11 ENST00000361696.10
UTS2
urotensin 2
chr17_-_69268812 0.11 ENST00000586811.1
ABCA5
ATP binding cassette subfamily A member 5
chr6_+_43770707 0.11 ENST00000324450.11
ENST00000417285.7
ENST00000413642.8
ENST00000372055.9
ENST00000482630.7
ENST00000425836.7
ENST00000372064.9
ENST00000372077.8
ENST00000519767.5
VEGFA
vascular endothelial growth factor A
chr6_+_43770202 0.11 ENST00000372067.8
ENST00000672860.2
VEGFA
vascular endothelial growth factor A
chr4_+_87975667 0.11 ENST00000237623.11
ENST00000682655.1
ENST00000508233.6
ENST00000360804.4
ENST00000395080.8
SPP1
secreted phosphoprotein 1
chr15_-_66386668 0.11 ENST00000568216.5
ENST00000562124.5
ENST00000570251.1
TIPIN
TIMELESS interacting protein
chr19_-_3500664 0.11 ENST00000427575.6
DOHH
deoxyhypusine hydroxylase
chr6_+_83193331 0.11 ENST00000369724.5
RWDD2A
RWD domain containing 2A
chr4_+_85604146 0.10 ENST00000512201.5
ARHGAP24
Rho GTPase activating protein 24
chr15_-_55917129 0.10 ENST00000338963.6
ENST00000508342.5
NEDD4
NEDD4 E3 ubiquitin protein ligase
chr4_+_185395979 0.10 ENST00000507753.1
ANKRD37
ankyrin repeat domain 37
chr5_-_161546708 0.10 ENST00000393959.6
GABRB2
gamma-aminobutyric acid type A receptor subunit beta2
chr14_-_56805648 0.10 ENST00000554788.5
ENST00000554845.1
ENST00000408990.8
OTX2
orthodenticle homeobox 2
chr8_+_106726012 0.10 ENST00000449762.6
ENST00000297447.10
OXR1
oxidation resistance 1
chr9_+_92974476 0.10 ENST00000337352.10
FGD3
FYVE, RhoGEF and PH domain containing 3
chr2_+_225399684 0.10 ENST00000636099.1
NYAP2
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr5_+_72848161 0.10 ENST00000506351.6
TNPO1
transportin 1
chr19_+_21082140 0.10 ENST00000616183.1
ENST00000596053.5
ZNF714
zinc finger protein 714
chr13_+_23570370 0.10 ENST00000403372.6
ENST00000248484.9
TNFRSF19
TNF receptor superfamily member 19
chr6_+_26156323 0.09 ENST00000304218.6
H1-4
H1.4 linker histone, cluster member
chr10_-_95069489 0.09 ENST00000371270.6
ENST00000535898.5
ENST00000623108.3
CYP2C8
cytochrome P450 family 2 subfamily C member 8
chr14_+_56117702 0.09 ENST00000559044.5
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr12_-_49187369 0.09 ENST00000547939.6
TUBA1A
tubulin alpha 1a
chr15_+_63122561 0.09 ENST00000557972.1
LACTB
lactamase beta
chr9_+_60914407 0.09 ENST00000437823.5
SPATA31A5
SPATA31 subfamily A member 5
chr6_+_12717660 0.09 ENST00000674637.1
PHACTR1
phosphatase and actin regulator 1
chr13_+_24270681 0.09 ENST00000343003.10
ENST00000399949.6
SPATA13
spermatogenesis associated 13
chr19_-_3500625 0.09 ENST00000672935.1
DOHH
deoxyhypusine hydroxylase
chr12_-_84892120 0.09 ENST00000680379.1
SLC6A15
solute carrier family 6 member 15
chr3_-_9880250 0.09 ENST00000423850.5
ENST00000336832.7
ENST00000675828.1
ENST00000618572.4
ENST00000455015.6
CIDEC
cell death inducing DFFA like effector c
chr9_+_102995308 0.09 ENST00000612124.4
ENST00000374798.8
ENST00000487798.5
CYLC2
cylicin 2
chr17_-_31297231 0.09 ENST00000247271.5
OMG
oligodendrocyte myelin glycoprotein
chr4_-_56656448 0.08 ENST00000553379.6
HOPX
HOP homeobox
chr17_-_35142280 0.08 ENST00000586869.5
ENST00000442241.9
ENST00000360831.9
NLE1
notchless homolog 1
chr4_-_70666492 0.08 ENST00000254801.9
ENST00000391614.7
JCHAIN
joining chain of multimeric IgA and IgM
chr7_-_25228485 0.08 ENST00000222674.2
NPVF
neuropeptide VF precursor
chr1_+_117420597 0.08 ENST00000449370.6
MAN1A2
mannosidase alpha class 1A member 2
chr19_+_48393657 0.08 ENST00000263269.4
GRIN2D
glutamate ionotropic receptor NMDA type subunit 2D
chr12_-_91111460 0.08 ENST00000266718.5
LUM
lumican
chr14_-_25010604 0.08 ENST00000550887.5
STXBP6
syntaxin binding protein 6
chr5_+_122129533 0.08 ENST00000296600.5
ENST00000504912.1
ENST00000505843.1
ZNF474
zinc finger protein 474
chr19_+_29942205 0.08 ENST00000392271.6
URI1
URI1 prefoldin like chaperone
chr11_-_31811231 0.08 ENST00000438681.6
PAX6
paired box 6
chr4_-_56656507 0.08 ENST00000381255.7
ENST00000317745.11
ENST00000555760.6
ENST00000556614.6
HOPX
HOP homeobox
chr11_-_13496018 0.08 ENST00000529816.1
PTH
parathyroid hormone
chr16_-_21652598 0.08 ENST00000569602.1
ENST00000268389.6
IGSF6
immunoglobulin superfamily member 6
chr1_-_205121986 0.08 ENST00000367164.1
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit
chr4_-_56681588 0.08 ENST00000554144.5
ENST00000381260.7
HOPX
HOP homeobox
chr12_-_81598360 0.08 ENST00000333447.11
ENST00000407050.8
PPFIA2
PTPRF interacting protein alpha 2
chr11_-_31811034 0.08 ENST00000638250.1
PAX6
paired box 6
chr8_+_76681208 0.07 ENST00000651372.2
ZFHX4
zinc finger homeobox 4
chr7_+_16661182 0.07 ENST00000446596.5
ENST00000452975.6
ENST00000438834.5
BZW2
basic leucine zipper and W2 domains 2
chr1_-_205121964 0.07 ENST00000264515.11
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit
chr4_+_87832917 0.07 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
MEPE
matrix extracellular phosphoglycoprotein
chr12_-_8612850 0.07 ENST00000229335.11
ENST00000537228.5
AICDA
activation induced cytidine deaminase
chr13_+_76948500 0.07 ENST00000377462.6
ACOD1
aconitate decarboxylase 1
chr1_+_23019415 0.07 ENST00000465864.2
ENST00000356634.7
ENST00000400181.9
KDM1A
lysine demethylase 1A
chr5_+_141966820 0.07 ENST00000513019.5
ENST00000394519.5
ENST00000356143.5
RNF14
ring finger protein 14
chrX_-_54043927 0.07 ENST00000415025.5
ENST00000338946.10
PHF8
PHD finger protein 8
chr13_+_45464901 0.07 ENST00000349995.10
COG3
component of oligomeric golgi complex 3
chr3_-_197184131 0.07 ENST00000452595.5
DLG1
discs large MAGUK scaffold protein 1
chr4_-_52020332 0.07 ENST00000682860.1
LRRC66
leucine rich repeat containing 66
chr5_+_72848115 0.07 ENST00000679378.1
TNPO1
transportin 1
chr11_-_13495984 0.07 ENST00000282091.6
PTH
parathyroid hormone
chr8_-_94208548 0.06 ENST00000027335.8
ENST00000441892.6
ENST00000521491.1
CDH17
cadherin 17
chr1_-_247458105 0.06 ENST00000641149.1
ENST00000641527.1
OR2B11
olfactory receptor family 2 subfamily B member 11
chr19_-_51082883 0.06 ENST00000650543.2
KLK14
kallikrein related peptidase 14
chr14_+_79279403 0.06 ENST00000281127.11
NRXN3
neurexin 3
chr8_+_106726115 0.06 ENST00000521592.5
OXR1
oxidation resistance 1
chr12_+_55549602 0.06 ENST00000641569.1
ENST00000641851.1
OR6C4
olfactory receptor family 6 subfamily C member 4
chr6_+_131637296 0.06 ENST00000358229.6
ENST00000357639.8
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr14_-_106130061 0.06 ENST00000390602.3
IGHV3-13
immunoglobulin heavy variable 3-13
chr9_+_128787331 0.06 ENST00000223865.8
TBC1D13
TBC1 domain family member 13
chr3_+_138621207 0.06 ENST00000464668.5
FAIM
Fas apoptotic inhibitory molecule
chr11_-_40294089 0.06 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr16_-_48247533 0.06 ENST00000356608.7
ENST00000569991.1
ABCC11
ATP binding cassette subfamily C member 11
chr6_+_30328889 0.06 ENST00000396547.5
ENST00000623385.3
TRIM39
TRIM39-RPP21
tripartite motif containing 39
TRIM39-RPP21 readthrough
chr13_-_79405784 0.06 ENST00000267229.11
RBM26
RNA binding motif protein 26
chr21_+_33025927 0.06 ENST00000430860.1
ENST00000382357.4
ENST00000333337.3
OLIG2
oligodendrocyte transcription factor 2
chrX_-_15600953 0.06 ENST00000679212.1
ENST00000679278.1
ENST00000678046.1
ENST00000252519.8
ACE2
angiotensin I converting enzyme 2
chr11_-_31810991 0.06 ENST00000640684.1
PAX6
paired box 6
chr14_-_67533720 0.05 ENST00000554278.6
TMEM229B
transmembrane protein 229B
chr13_+_101452569 0.05 ENST00000618057.4
ITGBL1
integrin subunit beta like 1
chr2_+_196713117 0.05 ENST00000409270.5
CCDC150
coiled-coil domain containing 150
chr11_-_31811112 0.05 ENST00000640242.1
ENST00000640613.1
ENST00000606377.7
PAX6
paired box 6
chr12_-_18090141 0.05 ENST00000536890.1
RERGL
RERG like
chr13_-_103066411 0.05 ENST00000245312.5
SLC10A2
solute carrier family 10 member 2
chr6_+_111087495 0.05 ENST00000612036.4
ENST00000368851.10
SLC16A10
solute carrier family 16 member 10
chr1_+_209704836 0.05 ENST00000367027.5
HSD11B1
hydroxysteroid 11-beta dehydrogenase 1
chr5_-_36001006 0.05 ENST00000625798.2
UGT3A1
UDP glycosyltransferase family 3 member A1
chr11_-_31811140 0.05 ENST00000639916.1
PAX6
paired box 6
chr16_-_3018170 0.05 ENST00000572154.1
ENST00000328796.5
CLDN6
claudin 6
chr10_-_125816510 0.05 ENST00000650587.1
UROS
uroporphyrinogen III synthase
chr4_-_122456725 0.05 ENST00000226730.5
IL2
interleukin 2
chr2_-_240820945 0.05 ENST00000428768.2
ENST00000650053.1
ENST00000650130.1
KIF1A
kinesin family member 1A
chr15_-_43879835 0.05 ENST00000636859.1
FRMD5
FERM domain containing 5
chr9_+_122371036 0.05 ENST00000619306.5
ENST00000426608.6
ENST00000223423.8
PTGS1
prostaglandin-endoperoxide synthase 1
chrX_+_11293411 0.05 ENST00000348912.4
ENST00000380714.7
ENST00000380712.7
AMELX
amelogenin X-linked
chr12_-_71157872 0.05 ENST00000546561.2
TSPAN8
tetraspanin 8
chr1_+_154429315 0.05 ENST00000476006.5
IL6R
interleukin 6 receptor
chr17_-_41489907 0.05 ENST00000328119.11
KRT36
keratin 36

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.2 1.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.2 0.5 GO:0060279 positive regulation of ovulation(GO:0060279)
0.2 0.5 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 1.0 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.7 GO:1902731 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.1 0.5 GO:0035617 stress granule disassembly(GO:0035617)
0.1 0.3 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.3 GO:0060974 neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
0.1 0.9 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.2 GO:0051821 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821)
0.1 0.2 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.2 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 1.0 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.7 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.2 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.3 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.4 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.0 0.1 GO:0071335 submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.0 0.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.0 0.2 GO:0006041 glucosamine metabolic process(GO:0006041) glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.2 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.5 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.2 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.1 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.1 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.3 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.6 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.4 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.1 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.2 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.9 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.5 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.1 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.1 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0072573 propionate metabolic process(GO:0019541) cellular response to progesterone stimulus(GO:0071393) tolerance induction to lipopolysaccharide(GO:0072573)
0.0 0.1 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.1 GO:2001268 inner cell mass cell differentiation(GO:0001826) negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0 0.0 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760) negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.0 0.1 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.2 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.4 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.0 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.0 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.2 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 1.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 1.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 1.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.5 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.3 GO:0097179 protease inhibitor complex(GO:0097179)
0.1 0.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.7 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 1.0 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.2 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.1 GO:0071756 dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752) IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0070449 elongin complex(GO:0070449)
0.0 0.3 GO:0097381 photoreceptor disc membrane(GO:0097381)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.2 0.9 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.3 GO:0042008 interleukin-33 binding(GO:0002113) interleukin-18 receptor activity(GO:0042008)
0.1 0.9 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.1 0.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.4 GO:0004882 androgen receptor activity(GO:0004882)
0.1 0.3 GO:0061714 folic acid receptor activity(GO:0061714)
0.1 0.2 GO:1902271 D3 vitamins binding(GO:1902271)
0.1 0.7 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.5 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.1 GO:0052852 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.0 1.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.9 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 1.1 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.8 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.4 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.4 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.0 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.0 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.0 0.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.1 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.5 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.2 GO:0008061 chitin binding(GO:0008061)
0.0 0.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.0 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.2 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.6 PID IL23 PATHWAY IL23-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.1 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.1 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling