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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for HOXA4

Z-value: 0.53

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Transcription factors associated with HOXA4

Gene Symbol Gene ID Gene Info
ENSG00000197576.14 HOXA4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA4hg38_v1_chr7_-_27130733_271307800.536.7e-03Click!

Activity profile of HOXA4 motif

Sorted Z-values of HOXA4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr20_+_54475584 1.30 ENST00000262593.10
docking protein 5
chr20_+_54475647 1.22 ENST00000395939.5
docking protein 5
chr1_+_28259473 1.09 ENST00000253063.4
sestrin 2
chr5_-_59430600 0.98 ENST00000636120.1
phosphodiesterase 4D
chr19_+_12838437 0.78 ENST00000251472.9
microtubule associated serine/threonine kinase 1
chr5_-_124746630 0.76 ENST00000513986.2
zinc finger protein 608
chr1_+_158461574 0.72 ENST00000641432.1
ENST00000641460.1
ENST00000641535.1
ENST00000641971.1
olfactory receptor family 10 subfamily K member 1
chr15_+_74788542 0.58 ENST00000567571.5
C-terminal Src kinase
chr5_+_68290637 0.56 ENST00000336483.9
phosphoinositide-3-kinase regulatory subunit 1
chr5_+_53480619 0.55 ENST00000396947.7
ENST00000256759.8
follistatin
chr10_-_90921079 0.54 ENST00000371697.4
ankyrin repeat domain 1
chr7_-_13986439 0.53 ENST00000443608.5
ENST00000438956.5
ETS variant transcription factor 1
chr6_+_12716760 0.51 ENST00000332995.12
phosphatase and actin regulator 1
chr2_-_68871382 0.50 ENST00000295379.2
bone morphogenetic protein 10
chr4_-_152352800 0.47 ENST00000393956.9
F-box and WD repeat domain containing 7
chr2_+_167187364 0.45 ENST00000672671.1
xin actin binding repeat containing 2
chr7_-_27130733 0.43 ENST00000428284.2
ENST00000360046.10
ENST00000610970.1
homeobox A4
chr17_-_41055211 0.43 ENST00000542910.1
ENST00000398477.1
keratin associated protein 2-2
chr12_-_119803383 0.41 ENST00000392520.2
ENST00000678677.1
ENST00000679249.1
ENST00000676849.1
citron rho-interacting serine/threonine kinase
chr12_+_71664352 0.40 ENST00000547843.1
THAP domain containing 2
chr2_-_179562576 0.38 ENST00000336917.9
zinc finger protein 385B
chr8_-_10655137 0.38 ENST00000382483.4
RP1 like 1
chr17_-_10549694 0.37 ENST00000622564.4
myosin heavy chain 2
chr8_-_28490220 0.37 ENST00000517673.5
ENST00000380254.7
ENST00000518734.5
ENST00000346498.6
F-box protein 16
chr17_-_10549612 0.36 ENST00000532183.6
ENST00000397183.6
ENST00000420805.1
myosin heavy chain 2
chr17_-_10549652 0.35 ENST00000245503.10
myosin heavy chain 2
chr18_+_31376777 0.34 ENST00000308128.9
ENST00000359747.4
desmoglein 4
chrM_+_5824 0.34 ENST00000361624.2
mitochondrially encoded cytochrome c oxidase I
chr17_-_79950828 0.34 ENST00000572862.5
ENST00000573782.5
ENST00000574427.1
ENST00000570373.5
ENST00000340848.11
ENST00000576768.5
TBC1 domain family member 16
chr1_-_100178215 0.34 ENST00000370138.1
ENST00000370137.6
ENST00000342895.7
ENST00000620882.4
leucine rich repeat containing 39
chr2_-_80304274 0.33 ENST00000409148.1
ENST00000415098.1
ENST00000452811.1
leucine rich repeat transmembrane neuronal 1
chr13_-_46142834 0.33 ENST00000674665.1
lymphocyte cytosolic protein 1
chr5_-_38557459 0.33 ENST00000511561.1
LIF receptor subunit alpha
chr1_-_41918858 0.32 ENST00000372583.6
HIVEP zinc finger 3
chr11_-_16356538 0.31 ENST00000683767.1
SRY-box transcription factor 6
chr5_-_1882902 0.30 ENST00000231357.7
iroquois homeobox 4
chr6_+_12716801 0.30 ENST00000674595.1
phosphatase and actin regulator 1
chr1_+_167329044 0.30 ENST00000367862.9
POU class 2 homeobox 1
chr2_+_170715317 0.30 ENST00000375281.4
Sp5 transcription factor
chr15_+_89088417 0.30 ENST00000569550.5
ENST00000565066.5
ENST00000565973.5
ENST00000352732.10
abhydrolase domain containing 2, acylglycerol lipase
chr8_-_94436926 0.29 ENST00000481490.3
fibrinogen silencer binding protein
chr10_+_116545907 0.29 ENST00000369221.2
pancreatic lipase
chr1_-_41918666 0.28 ENST00000372584.5
HIVEP zinc finger 3
chr2_-_2324323 0.28 ENST00000648339.1
ENST00000647694.1
myelin transcription factor 1 like
chr17_+_44957907 0.28 ENST00000678938.1
N-myristoyltransferase 1
chr7_+_107470050 0.27 ENST00000304402.6
G protein-coupled receptor 22
chr6_+_12716554 0.27 ENST00000676159.1
phosphatase and actin regulator 1
chr20_-_46406582 0.27 ENST00000450812.5
ENST00000290246.11
ENST00000396391.5
engulfment and cell motility 2
chr7_+_144355288 0.26 ENST00000498580.5
ENST00000056217.10
Rho guanine nucleotide exchange factor 5
chr14_+_22515623 0.25 ENST00000390509.1
T cell receptor alpha joining 28
chr8_+_22567038 0.24 ENST00000523348.1
sorbin and SH3 domain containing 3
chr15_+_51377247 0.24 ENST00000396399.6
gliomedin
chr3_-_52452828 0.24 ENST00000496590.1
troponin C1, slow skeletal and cardiac type
chr6_+_99606833 0.24 ENST00000369215.5
PR/SET domain 13
chr22_+_25742141 0.24 ENST00000536101.5
ENST00000335473.12
ENST00000407587.6
myosin XVIIIB
chr1_+_155689074 0.23 ENST00000343043.7
ENST00000421487.6
ENST00000535183.5
ENST00000368336.10
ENST00000465375.5
ENST00000470830.5
death associated protein 3
chr16_+_7332839 0.23 ENST00000355637.9
RNA binding fox-1 homolog 1
chr10_-_67696115 0.22 ENST00000433211.7
catenin alpha 3
chr4_+_15427998 0.22 ENST00000444304.3
C1q and TNF related 7
chr2_-_162243375 0.22 ENST00000188790.9
ENST00000443424.5
fibroblast activation protein alpha
chr2_-_162242998 0.22 ENST00000627638.2
ENST00000447386.5
fibroblast activation protein alpha
chr16_+_7332744 0.21 ENST00000436368.6
ENST00000311745.9
ENST00000340209.8
ENST00000620507.4
RNA binding fox-1 homolog 1
chrX_-_85379659 0.21 ENST00000262753.9
POF1B actin binding protein
chr11_+_27041313 0.21 ENST00000528583.5
gamma-butyrobetaine hydroxylase 1
chr4_+_87832917 0.21 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
matrix extracellular phosphoglycoprotein
chr3_-_120682215 0.21 ENST00000283871.10
homogentisate 1,2-dioxygenase
chr7_+_100867379 0.21 ENST00000200457.9
ENST00000619988.4
thyroid hormone receptor interactor 6
chr19_-_893172 0.21 ENST00000325464.6
ENST00000312090.10
mediator complex subunit 16
chr14_+_50560137 0.21 ENST00000358385.12
atlastin GTPase 1
chr14_+_36661852 0.21 ENST00000361487.7
paired box 9
chr2_-_80304700 0.20 ENST00000295057.4
leucine rich repeat transmembrane neuronal 1
chr1_+_160190567 0.20 ENST00000368078.8
calsequestrin 1
chr10_-_104085847 0.20 ENST00000648076.2
collagen type XVII alpha 1 chain
chr7_+_114416286 0.20 ENST00000635534.1
forkhead box P2
chr1_-_204359885 0.20 ENST00000414478.1
ENST00000272203.8
pleckstrin homology domain containing A6
chr8_+_76681208 0.20 ENST00000651372.2
zinc finger homeobox 4
chr17_-_10421944 0.20 ENST00000403437.2
myosin heavy chain 8
chr3_+_188947199 0.19 ENST00000433971.5
tumor protein p63 regulated 1
chrX_-_54998530 0.19 ENST00000545676.5
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr12_-_56643499 0.19 ENST00000551570.5
ATP synthase F1 subunit beta
chr15_+_90201301 0.19 ENST00000411539.6
semaphorin 4B
chr11_+_5351508 0.19 ENST00000380219.1
olfactory receptor family 51 subfamily B member 6
chr6_+_31546845 0.19 ENST00000376146.8
NFKB inhibitor like 1
chr11_+_112175526 0.18 ENST00000532612.5
ENST00000438022.5
beta-carotene oxygenase 2
chr7_-_29195186 0.18 ENST00000449801.5
ENST00000409850.5
carboxypeptidase vitellogenic like
chr14_+_39265278 0.18 ENST00000554392.5
ENST00000555716.5
ENST00000341749.7
ENST00000557038.5
MIA SH3 domain ER export factor 2
chr17_-_10518536 0.17 ENST00000226207.6
myosin heavy chain 1
chr7_+_95485898 0.17 ENST00000428113.5
ankyrin repeat and SOCS box containing 4
chr19_-_893200 0.17 ENST00000269814.8
ENST00000395808.7
mediator complex subunit 16
chr7_+_100676112 0.17 ENST00000412215.5
ENST00000393924.1
G protein subunit beta 2
chr8_-_42501224 0.17 ENST00000520262.6
ENST00000517366.1
solute carrier family 20 member 2
chr7_+_95485934 0.17 ENST00000325885.6
ankyrin repeat and SOCS box containing 4
chr20_+_33562365 0.16 ENST00000346541.7
ENST00000397800.5
ENST00000492345.5
CBFA2/RUNX1 partner transcriptional co-repressor 2
chr9_-_110999458 0.16 ENST00000374430.6
lysophosphatidic acid receptor 1
chr10_-_60572599 0.15 ENST00000503366.5
ankyrin 3
chr17_-_50707855 0.15 ENST00000285243.7
ankyrin repeat domain 40
chr1_-_107688492 0.15 ENST00000415432.6
vav guanine nucleotide exchange factor 3
chrX_-_85379703 0.14 ENST00000373145.3
POF1B actin binding protein
chr3_-_57199938 0.14 ENST00000473921.2
ENST00000295934.8
HESX homeobox 1
chr13_-_83882390 0.14 ENST00000377084.3
SLIT and NTRK like family member 1
chr6_-_116126120 0.13 ENST00000452729.1
ENST00000651968.1
ENST00000243222.8
collagen type X alpha 1 chain
chr7_+_129375643 0.13 ENST00000490911.5
adenosylhomocysteinase like 2
chr9_+_92964272 0.13 ENST00000468206.6
FYVE, RhoGEF and PH domain containing 3
chr6_-_55875583 0.13 ENST00000370830.4
bone morphogenetic protein 5
chr9_+_84669760 0.13 ENST00000304053.10
neurotrophic receptor tyrosine kinase 2
chr11_-_59615673 0.12 ENST00000263847.6
oxysterol binding protein
chr2_+_54456311 0.12 ENST00000615901.4
ENST00000356805.9
spectrin beta, non-erythrocytic 1
chr1_-_193106048 0.12 ENST00000367440.3
glutaredoxin 2
chrX_-_123623155 0.12 ENST00000618150.4
THO complex 2
chr5_+_153490655 0.12 ENST00000518142.5
ENST00000285900.10
glutamate ionotropic receptor AMPA type subunit 1
chr6_+_50818857 0.12 ENST00000393655.4
transcription factor AP-2 beta
chr2_-_2324642 0.12 ENST00000650485.1
ENST00000649207.1
myelin transcription factor 1 like
chrX_+_41688967 0.12 ENST00000378142.9
G protein-coupled receptor 34
chr17_-_10469558 0.12 ENST00000255381.2
myosin heavy chain 4
chr11_+_112175501 0.11 ENST00000357685.11
ENST00000361053.8
beta-carotene oxygenase 2
chr12_+_53425070 0.11 ENST00000550839.1
anti-Mullerian hormone receptor type 2
chr11_-_62545629 0.11 ENST00000528508.5
ENST00000533365.5
AHNAK nucleoprotein
chr14_-_37595224 0.11 ENST00000250448.5
forkhead box A1
chr11_-_5343524 0.11 ENST00000300773.3
olfactory receptor family 51 subfamily B member 5
chr9_-_110579880 0.11 ENST00000401783.6
ENST00000374461.1
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr9_+_84669707 0.11 ENST00000277120.8
ENST00000323115.10
neurotrophic receptor tyrosine kinase 2
chr5_+_55853464 0.11 ENST00000652039.1
interleukin 31 receptor A
chr12_+_54053815 0.10 ENST00000430889.3
homeobox C4
chr9_-_110579704 0.10 ENST00000374469.6
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr3_-_62374293 0.10 ENST00000486811.5
FEZ family zinc finger 2
chr2_-_190062721 0.10 ENST00000260950.5
myostatin
chr3_-_42702778 0.10 ENST00000457462.5
ENST00000441594.6
hedgehog acyltransferase like
chr11_+_124183219 0.09 ENST00000641351.2
olfactory receptor family 10 subfamily D member 3
chr12_+_106582996 0.09 ENST00000392842.6
regulatory factor X4
chr5_+_70025247 0.09 ENST00000380751.9
ENST00000380750.8
ENST00000503931.5
ENST00000506542.1
small EDRK-rich factor 1B
chr12_-_86256267 0.09 ENST00000620241.4
MGAT4 family member C
chr18_-_23437927 0.09 ENST00000578520.5
ENST00000383233.8
transmembrane protein 241
chr18_-_26548527 0.08 ENST00000580059.7
potassium channel tetramerization domain containing 1
chr1_-_113871665 0.08 ENST00000528414.5
ENST00000460620.5
ENST00000359785.10
ENST00000420377.6
ENST00000525799.1
ENST00000538253.5
protein tyrosine phosphatase non-receptor type 22
chr12_-_91004965 0.08 ENST00000261172.8
epiphycan
chr10_+_11005301 0.08 ENST00000416382.6
ENST00000631460.1
ENST00000631816.1
CUGBP Elav-like family member 2
chr7_+_117611617 0.08 ENST00000468795.1
CF transmembrane conductance regulator
chr6_-_116829037 0.07 ENST00000368549.7
ENST00000530250.1
ENST00000310357.8
G protein-coupled receptor class C group 6 member A
chr22_+_22588155 0.07 ENST00000390302.3
immunoglobulin lambda variable 2-33 (non-functional)
chr11_+_124611420 0.07 ENST00000284288.3
pannexin 3
chr12_+_12785652 0.07 ENST00000356591.5
apolipoprotein L domain containing 1
chr12_+_49750598 0.07 ENST00000552370.5
transmembrane BAX inhibitor motif containing 6
chr5_+_148203024 0.07 ENST00000325630.3
serine peptidase inhibitor Kazal type 6
chr5_+_66958870 0.07 ENST00000405643.5
ENST00000407621.1
ENST00000432426.5
microtubule associated serine/threonine kinase family member 4
chrX_-_120311408 0.07 ENST00000309720.9
transmembrane protein 255A
chrX_-_120311452 0.07 ENST00000371369.9
transmembrane protein 255A
chrX_+_41689006 0.07 ENST00000378138.5
ENST00000620846.1
ENST00000649219.1
G protein-coupled receptor 34
chr7_-_13989658 0.06 ENST00000430479.6
ENST00000433547.1
ENST00000405192.6
ETS variant transcription factor 1
chr13_-_52848632 0.06 ENST00000377942.7
ENST00000338862.5
protocadherin 8
chr14_-_80231052 0.06 ENST00000557010.5
iodothyronine deiodinase 2
chr6_-_31546552 0.06 ENST00000303892.10
ENST00000376151.4
ATPase H+ transporting V1 subunit G2
chr13_-_83882456 0.06 ENST00000674365.1
SLIT and NTRK like family member 1
chr7_-_13986498 0.06 ENST00000420159.6
ENST00000399357.7
ENST00000403527.5
ETS variant transcription factor 1
chr10_-_93702508 0.06 ENST00000359204.5
FRA10A associated CGG repeat 1
chrX_-_120311533 0.05 ENST00000440464.5
ENST00000519908.1
transmembrane protein 255A
chr10_+_113125536 0.05 ENST00000349937.7
transcription factor 7 like 2
chr5_+_67004618 0.05 ENST00000261569.11
ENST00000436277.5
microtubule associated serine/threonine kinase family member 4
chr11_+_121101243 0.05 ENST00000392793.6
ENST00000642222.1
tectorin alpha
chr5_+_141430565 0.04 ENST00000613314.1
protocadherin gamma subfamily A, 12
chr5_+_148202771 0.04 ENST00000514389.5
ENST00000621437.4
serine peptidase inhibitor Kazal type 6
chr18_+_13612614 0.04 ENST00000586765.1
ENST00000677910.1
low density lipoprotein receptor class A domain containing 4
chrX_-_111410420 0.04 ENST00000371993.7
ENST00000680476.1
doublecortin
chr2_+_113067970 0.04 ENST00000341010.6
interleukin 1 family member 10
chr12_-_95073490 0.03 ENST00000330677.7
nuclear receptor subfamily 2 group C member 1
chr5_-_146182591 0.03 ENST00000510191.5
ENST00000674277.1
ENST00000674447.1
ENST00000674270.1
ENST00000394434.7
ENST00000674290.1
ENST00000674398.1
ENST00000674174.1
leucyl-tRNA synthetase 1
chr17_-_48593748 0.03 ENST00000239151.6
homeobox B5
chr2_+_53767772 0.03 ENST00000295304.5
ChaC glutathione specific gamma-glutamylcyclotransferase 2
chr12_-_86256299 0.03 ENST00000552808.6
ENST00000547225.5
MGAT4 family member C
chr5_-_146182475 0.02 ENST00000674158.1
ENST00000674191.1
ENST00000274562.13
leucyl-tRNA synthetase 1
chr11_-_13496018 0.02 ENST00000529816.1
parathyroid hormone
chr12_+_53454764 0.02 ENST00000439930.7
ENST00000548933.5
poly(rC) binding protein 2
chr5_+_159916475 0.02 ENST00000306675.5
adrenoceptor alpha 1B
chr10_-_73655984 0.02 ENST00000394810.3
synaptopodin 2 like
chr16_+_6483379 0.02 ENST00000552089.5
RNA binding fox-1 homolog 1
chr4_-_184217854 0.01 ENST00000296741.7
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr5_+_153491174 0.01 ENST00000521843.6
glutamate ionotropic receptor AMPA type subunit 1
chr6_+_63211446 0.01 ENST00000370659.1
FKBP prolyl isomerase family member 1C
chr7_-_13988863 0.01 ENST00000405358.8
ETS variant transcription factor 1
chr15_+_36702009 0.01 ENST00000562489.1
CDAN1 interacting nuclease 1
chr3_+_122384167 0.01 ENST00000232125.9
ENST00000477892.5
ENST00000469967.1
family with sequence similarity 162 member A
chr1_+_26021768 0.01 ENST00000374280.4
exostosin like glycosyltransferase 1
chr10_-_119178791 0.00 ENST00000298510.4
peroxiredoxin 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 2.5 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.1 0.5 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.4 GO:0097325 melanocyte proliferation(GO:0097325)
0.1 0.3 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
0.1 0.3 GO:0016122 tetraterpenoid metabolic process(GO:0016108) carotenoid metabolic process(GO:0016116) carotene catabolic process(GO:0016121) xanthophyll metabolic process(GO:0016122) terpene catabolic process(GO:0046247)
0.1 1.0 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.6 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 0.2 GO:0002086 diaphragm contraction(GO:0002086)
0.1 0.2 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.1 0.3 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.1 0.2 GO:0021758 caudate nucleus development(GO:0021757) putamen development(GO:0021758)
0.1 0.3 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.1 0.3 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 1.1 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.3 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.0 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.2 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.0 0.2 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.5 GO:0007512 adult heart development(GO:0007512)
0.0 0.1 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.0 0.6 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.0 0.2 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.1 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.6 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.7 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.5 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:1902613 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.0 0.1 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.5 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.3 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.2 GO:0014877 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.3 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.3 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.1 GO:0031438 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.1 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.3 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.2 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:0042262 DNA protection(GO:0042262)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.6 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 1.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.5 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.4 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.3 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.5 GO:0032982 myosin filament(GO:0032982)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 1.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 1.1 GO:0070728 leucine binding(GO:0070728)
0.1 0.3 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.1 0.2 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1 0.4 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.3 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.5 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 2.5 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.5 GO:0031433 telethonin binding(GO:0031433)
0.0 1.2 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.6 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.6 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 1.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 0.6 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0030613 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.5 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.9 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.2 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.6 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 1.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events