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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for HOXB2_UNCX_HOXD3

Z-value: 0.61

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Transcription factors associated with HOXB2_UNCX_HOXD3

Gene Symbol Gene ID Gene Info
ENSG00000173917.11 HOXB2
ENSG00000164853.9 UNCX
ENSG00000128652.12 HOXD3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB2hg38_v1_chr17_-_48545077_48545117-0.386.1e-02Click!
HOXD3hg38_v1_chr2_+_176157293_176157332-0.125.8e-01Click!

Activity profile of HOXB2_UNCX_HOXD3 motif

Sorted Z-values of HOXB2_UNCX_HOXD3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB2_UNCX_HOXD3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_150765735 1.22 ENST00000679898.1
ENST00000448301.7
ENST00000680664.1
ENST00000679512.1
ENST00000368985.8
ENST00000679582.1
cathepsin S
chr1_-_150765785 1.21 ENST00000680311.1
ENST00000681728.1
ENST00000680288.1
cathepsin S
chr4_-_76023489 1.07 ENST00000306602.3
C-X-C motif chemokine ligand 10
chr10_-_48652493 1.04 ENST00000435790.6
Rho GTPase activating protein 22
chr12_+_26195313 0.96 ENST00000422622.3
sarcospan
chr17_-_41149823 0.92 ENST00000343246.6
keratin associated protein 4-5
chr6_+_127577168 0.83 ENST00000329722.8
chromosome 6 open reading frame 58
chr10_+_89392546 0.81 ENST00000546318.2
ENST00000371804.4
interferon induced protein with tetratricopeptide repeats 1
chr4_+_168092530 0.80 ENST00000359299.8
annexin A10
chr7_-_24980148 0.78 ENST00000313367.7
oxysterol binding protein like 3
chr16_+_53099100 0.78 ENST00000565832.5
chromodomain helicase DNA binding protein 9
chr2_-_207167220 0.78 ENST00000421199.5
ENST00000457962.5
Kruppel like factor 7
chr11_-_102780620 0.73 ENST00000279441.9
ENST00000539681.1
matrix metallopeptidase 10
chr12_+_112906777 0.73 ENST00000452357.7
ENST00000445409.7
2'-5'-oligoadenylate synthetase 1
chr10_-_13707536 0.73 ENST00000632570.1
ENST00000477221.2
FERM domain containing 4A
chr10_+_24208774 0.69 ENST00000376456.8
ENST00000458595.5
ENST00000376452.7
ENST00000430453.6
KIAA1217
chr2_-_224947030 0.67 ENST00000409592.7
dedicator of cytokinesis 10
chr17_+_43006740 0.66 ENST00000438323.2
ENST00000415816.7
interferon induced protein 35
chr12_+_78036248 0.66 ENST00000644176.1
neuron navigator 3
chr2_+_112095189 0.65 ENST00000649734.1
transmembrane protein 87B
chr18_+_34593312 0.64 ENST00000591816.6
ENST00000588125.5
ENST00000684610.1
ENST00000683705.1
ENST00000598334.5
ENST00000588684.5
ENST00000554864.7
ENST00000399121.9
ENST00000595022.5
dystrobrevin alpha
chr12_+_26195543 0.63 ENST00000242729.7
sarcospan
chr9_+_12693327 0.62 ENST00000388918.10
tyrosinase related protein 1
chr3_+_173398438 0.62 ENST00000457714.5
neuroligin 1
chr8_-_85341659 0.59 ENST00000522389.5
carbonic anhydrase 1
chr3_-_172711005 0.59 ENST00000424772.2
ENST00000475381.7
neutral cholesterol ester hydrolase 1
chr7_-_93148345 0.57 ENST00000437805.5
ENST00000446959.5
ENST00000439952.5
ENST00000414791.5
ENST00000446033.1
ENST00000411955.5
ENST00000318238.9
sterile alpha motif domain containing 9 like
chr12_-_88580459 0.57 ENST00000552044.1
ENST00000644744.1
ENST00000357116.4
KIT ligand
chr4_-_76007501 0.55 ENST00000264888.6
C-X-C motif chemokine ligand 9
chr6_+_113857333 0.55 ENST00000612661.2
myristoylated alanine rich protein kinase C substrate
chr11_-_105035113 0.54 ENST00000526568.5
ENST00000531166.5
ENST00000534497.5
ENST00000527979.5
ENST00000533400.6
ENST00000528974.1
ENST00000525825.5
ENST00000353247.9
ENST00000446369.5
ENST00000436863.7
caspase 1
chr11_-_117877463 0.54 ENST00000527717.5
FXYD domain containing ion transport regulator 6
chr18_-_36122110 0.53 ENST00000586829.1
solute carrier family 39 member 6
chr5_+_172641241 0.52 ENST00000369800.6
ENST00000520919.5
ENST00000522853.5
neuralized E3 ubiquitin protein ligase 1B
chr10_-_27240505 0.52 ENST00000375888.5
ENST00000676732.1
acyl-CoA binding domain containing 5
chr5_-_151093566 0.52 ENST00000521001.1
TNFAIP3 interacting protein 1
chr18_+_34593392 0.51 ENST00000684377.1
dystrobrevin alpha
chr10_-_14330879 0.51 ENST00000357447.7
FERM domain containing 4A
chr7_-_122699108 0.50 ENST00000340112.3
ring finger protein 133
chr1_+_67685170 0.50 ENST00000370985.4
ENST00000370986.9
ENST00000650283.1
ENST00000648742.1
growth arrest and DNA damage inducible alpha
chr7_-_25228485 0.48 ENST00000222674.2
neuropeptide VF precursor
chr3_+_190615308 0.47 ENST00000412080.1
interleukin 1 receptor accessory protein
chr7_-_116030735 0.47 ENST00000393485.5
transcription factor EC
chr10_+_94683771 0.47 ENST00000339022.6
cytochrome P450 family 2 subfamily C member 18
chr1_-_7940825 0.45 ENST00000377507.8
TNF receptor superfamily member 9
chr16_-_53703883 0.45 ENST00000262135.9
ENST00000564374.5
ENST00000566096.5
RPGRIP1 like
chr10_+_27532521 0.45 ENST00000683924.1
RAB18, member RAS oncogene family
chr8_+_104223344 0.45 ENST00000523362.5
regulating synaptic membrane exocytosis 2
chr4_+_94995919 0.44 ENST00000509540.6
bone morphogenetic protein receptor type 1B
chr11_+_33039996 0.44 ENST00000432887.5
ENST00000528898.1
ENST00000531632.6
t-complex 11 like 1
chr6_+_63521738 0.44 ENST00000648894.1
ENST00000639568.2
protein tyrosine phosphatase 4A1
chr18_-_36129305 0.43 ENST00000269187.10
ENST00000590986.5
ENST00000440549.6
solute carrier family 39 member 6
chr6_+_167291329 0.43 ENST00000366829.2
unc-93 homolog A
chr7_-_116030750 0.43 ENST00000265440.12
ENST00000320239.11
transcription factor EC
chr8_+_106447918 0.42 ENST00000442977.6
oxidation resistance 1
chr14_+_32329256 0.42 ENST00000280979.9
A-kinase anchoring protein 6
chr5_-_173328407 0.42 ENST00000265087.9
stanniocalcin 2
chr2_+_167135901 0.42 ENST00000628543.2
xin actin binding repeat containing 2
chr4_+_94974984 0.41 ENST00000672698.1
bone morphogenetic protein receptor type 1B
chr21_-_36542600 0.41 ENST00000399136.5
claudin 14
chr3_+_130850585 0.41 ENST00000505330.5
ENST00000504381.5
ENST00000507488.6
ATPase secretory pathway Ca2+ transporting 1
chr2_+_151357583 0.40 ENST00000243347.5
TNF alpha induced protein 6
chr7_+_138460238 0.39 ENST00000343526.9
tripartite motif containing 24
chr16_-_53703810 0.39 ENST00000569716.1
ENST00000562588.5
ENST00000621565.5
ENST00000562230.5
ENST00000563746.5
ENST00000568653.7
ENST00000647211.2
RPGRIP1 like
chr6_-_134318097 0.39 ENST00000367858.10
ENST00000533224.1
serum/glucocorticoid regulated kinase 1
chr4_-_102828048 0.39 ENST00000508249.1
ubiquitin conjugating enzyme E2 D3
chr6_-_32838727 0.39 ENST00000652259.1
ENST00000374897.4
ENST00000620123.4
ENST00000452392.2
transporter 2, ATP binding cassette subfamily B member
novel protein, TAP2-HLA-DOB readthrough
chr19_-_3557563 0.38 ENST00000389395.7
ENST00000355415.7
major facilitator superfamily domain containing 12
chr6_+_26365215 0.37 ENST00000527422.5
ENST00000356386.6
ENST00000396948.5
butyrophilin subfamily 3 member A2
chr1_-_153549120 0.37 ENST00000368712.1
S100 calcium binding protein A3
chr8_+_49911604 0.36 ENST00000642164.1
ENST00000644093.1
ENST00000643999.1
ENST00000647073.1
ENST00000646880.1
syntrophin gamma 1
chr3_-_191282383 0.36 ENST00000427544.6
urotensin 2B
chr6_+_26365176 0.36 ENST00000377708.7
butyrophilin subfamily 3 member A2
chr6_+_167291309 0.36 ENST00000230256.8
unc-93 homolog A
chrX_+_30243715 0.36 ENST00000378981.8
ENST00000397550.6
MAGE family member B1
chr3_-_157503574 0.35 ENST00000494677.5
ENST00000468233.5
ventricular zone expressed PH domain containing 1
chr13_+_38349822 0.35 ENST00000379649.5
ENST00000239878.9
ubiquitin fold modifier 1
chr11_+_35186820 0.35 ENST00000531110.6
ENST00000525685.6
CD44 molecule (Indian blood group)
chr9_+_131289685 0.35 ENST00000372264.4
phospholipid phosphatase 7 (inactive)
chr7_-_22194709 0.35 ENST00000458533.5
Rap guanine nucleotide exchange factor 5
chr2_+_186590022 0.35 ENST00000261023.8
ENST00000374907.7
integrin subunit alpha V
chr21_+_30396030 0.35 ENST00000355459.4
keratin associated protein 13-1
chr10_+_13099585 0.35 ENST00000378764.6
optineurin
chr11_+_24496988 0.35 ENST00000336930.11
leucine zipper protein 2
chr1_+_206635521 0.34 ENST00000367109.8
dual specificity tyrosine phosphorylation regulated kinase 3
chr21_+_25639272 0.34 ENST00000400532.5
ENST00000312957.9
junctional adhesion molecule 2
chr8_-_118951876 0.34 ENST00000297350.9
TNF receptor superfamily member 11b
chr6_+_13272709 0.34 ENST00000379335.8
phosphatase and actin regulator 1
chr17_-_41055211 0.34 ENST00000542910.1
ENST00000398477.1
keratin associated protein 2-2
chr8_+_22567038 0.33 ENST00000523348.1
sorbin and SH3 domain containing 3
chr12_+_10505602 0.33 ENST00000322446.3
eukaryotic translation initiation factor 2 subunit gamma B
chr18_+_63887698 0.33 ENST00000457692.5
ENST00000299502.9
ENST00000413956.5
serpin family B member 2
chr21_+_25639251 0.33 ENST00000480456.6
junctional adhesion molecule 2
chr22_+_18150162 0.33 ENST00000215794.8
ubiquitin specific peptidase 18
chr2_+_68734861 0.33 ENST00000467265.5
Rho GTPase activating protein 25
chr4_-_75724386 0.32 ENST00000677606.1
ENST00000678798.1
ENST00000677970.1
ENST00000677620.1
ENST00000679281.1
ENST00000677333.1
ENST00000676470.1
ENST00000499709.3
ENST00000511868.6
ENST00000678971.1
ENST00000677265.1
ENST00000677952.1
ENST00000678122.1
ENST00000678100.1
ENST00000678062.1
ENST00000676666.1
G3BP stress granule assembly factor 2
chr22_+_20774092 0.32 ENST00000215727.10
serpin family D member 1
chr19_-_40882226 0.32 ENST00000301146.9
cytochrome P450 family 2 subfamily A member 7
chr6_+_122996227 0.32 ENST00000275162.10
clavesin 2
chr1_+_168179030 0.32 ENST00000367830.3
TOR signaling pathway regulator
chr14_+_34993240 0.31 ENST00000677647.1
signal recognition particle 54
chr20_+_33217325 0.31 ENST00000375452.3
ENST00000375454.8
BPI fold containing family A member 3
chr4_-_39977836 0.31 ENST00000303538.13
ENST00000503396.5
PDS5 cohesin associated factor A
chr19_-_45584810 0.31 ENST00000323060.3
outer mitochondrial membrane lipid metabolism regulator OPA3
chr17_+_76467597 0.31 ENST00000392492.8
aralkylamine N-acetyltransferase
chr15_+_45252228 0.31 ENST00000560438.5
ENST00000347644.8
solute carrier family 28 member 2
chr17_-_41124178 0.31 ENST00000394014.2
keratin associated protein 4-12
chrX_-_15314543 0.31 ENST00000344384.8
ankyrin repeat and SOCS box containing 11
chr1_-_88891496 0.31 ENST00000448623.5
ENST00000370500.10
ENST00000418217.1
general transcription factor IIB
chr10_+_13099440 0.30 ENST00000263036.9
optineurin
chr10_-_73591330 0.30 ENST00000451492.5
ENST00000681793.1
ENST00000680396.1
ENST00000413442.5
ubiquitin specific peptidase 54
chr11_-_117876719 0.30 ENST00000529335.6
ENST00000260282.8
FXYD domain containing ion transport regulator 6
chr11_-_89921767 0.30 ENST00000530311.6
tripartite motif containing 49D1
chr1_+_70411241 0.30 ENST00000370938.8
ENST00000346806.2
cystathionine gamma-lyase
chr11_+_92969651 0.30 ENST00000257068.3
ENST00000528076.1
melatonin receptor 1B
chr7_-_107803215 0.29 ENST00000340010.10
ENST00000453332.1
solute carrier family 26 member 3
chr5_+_136058849 0.29 ENST00000508076.5
transforming growth factor beta induced
chr21_-_14546297 0.29 ENST00000400566.6
ENST00000400564.5
SAM domain, SH3 domain and nuclear localization signals 1
chr11_-_96343170 0.29 ENST00000524717.6
mastermind like transcriptional coactivator 2
chr8_-_42377227 0.29 ENST00000220812.3
dickkopf WNT signaling pathway inhibitor 4
chr15_-_55270280 0.29 ENST00000564609.5
RAB27A, member RAS oncogene family
chr6_-_32941018 0.29 ENST00000418107.3
major histocompatibility complex, class II, DM beta
chr4_+_94207596 0.28 ENST00000359052.8
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr11_+_121102666 0.28 ENST00000264037.2
tectorin alpha
chr4_-_75724362 0.28 ENST00000677583.1
G3BP stress granule assembly factor 2
chr1_+_156194091 0.28 ENST00000684582.1
ENST00000359511.5
solute carrier family 25 member 44
chr13_-_33285682 0.28 ENST00000336934.10
StAR related lipid transfer domain containing 13
chr10_+_13100075 0.28 ENST00000378747.8
ENST00000378757.6
ENST00000378752.7
ENST00000378748.7
optineurin
chr11_-_117876892 0.27 ENST00000539526.5
FXYD domain containing ion transport regulator 6
chr11_+_89924064 0.27 ENST00000623787.3
tripartite motif containing 49D2
chr5_+_69565122 0.27 ENST00000507595.1
GTF2H2 family member C
chr4_-_102828022 0.27 ENST00000502690.5
ubiquitin conjugating enzyme E2 D3
chr9_-_21305313 0.27 ENST00000610521.2
interferon alpha 5
chr10_-_77637902 0.27 ENST00000286627.10
ENST00000639486.1
ENST00000640523.1
potassium calcium-activated channel subfamily M alpha 1
chr18_-_28036585 0.27 ENST00000399380.7
cadherin 2
chr3_+_155083523 0.27 ENST00000680057.1
membrane metalloendopeptidase
chr3_-_108058361 0.27 ENST00000398258.7
CD47 molecule
chr5_-_16916400 0.27 ENST00000513882.5
myosin X
chr2_+_68734773 0.27 ENST00000409202.8
Rho GTPase activating protein 25
chr12_+_96912517 0.27 ENST00000457368.2
NEDD1 gamma-tubulin ring complex targeting factor
chr2_+_102418642 0.27 ENST00000264260.6
interleukin 18 receptor accessory protein
chr5_+_132873660 0.27 ENST00000296877.3
liver enriched antimicrobial peptide 2
chr3_+_4680617 0.26 ENST00000648212.1
inositol 1,4,5-trisphosphate receptor type 1
chr11_+_35176696 0.26 ENST00000528455.5
CD44 molecule (Indian blood group)
chr20_-_18413216 0.26 ENST00000480488.2
double zinc ribbon and ankyrin repeat domains 1
chr20_+_18507520 0.26 ENST00000336714.8
ENST00000646240.1
ENST00000450074.6
ENST00000262544.6
SEC23 homolog B, COPII coat complex component
chr4_-_102827723 0.26 ENST00000349311.12
ubiquitin conjugating enzyme E2 D3
chr12_-_119804298 0.26 ENST00000678652.1
ENST00000678494.1
citron rho-interacting serine/threonine kinase
chr5_-_24644968 0.26 ENST00000264463.8
cadherin 10
chr17_-_41467386 0.26 ENST00000225899.4
keratin 32
chr8_-_30812867 0.26 ENST00000518243.5
protein phosphatase 2 catalytic subunit beta
chr15_+_41621492 0.26 ENST00000570161.6
MAX dimerization protein MGA
chr12_-_119803383 0.26 ENST00000392520.2
ENST00000678677.1
ENST00000679249.1
ENST00000676849.1
citron rho-interacting serine/threonine kinase
chr17_-_66229380 0.26 ENST00000205948.11
apolipoprotein H
chr8_+_49911396 0.26 ENST00000642720.2
syntrophin gamma 1
chr1_+_168178916 0.26 ENST00000367833.7
TOR signaling pathway regulator
chr17_+_46923075 0.26 ENST00000640608.1
ENST00000638634.1
ENST00000623037.2
ENST00000225567.9
ENST00000415811.7
ENST00000576910.7
ENST00000573224.2
ENST00000640621.1
ENST00000638892.1
ENST00000638838.1
ENST00000638216.1
ENST00000575949.6
ENST00000640806.1
ENST00000640269.1
ENST00000640443.1
ENST00000638697.1
ENST00000640051.2
ENST00000640007.1
ENST00000640711.1
ENST00000640495.1
ENST00000638374.1
ENST00000571048.1
ENST00000639287.1
ENST00000640138.1
ENST00000570879.2
ENST00000640068.1
ENST00000393456.7
ENST00000639031.1
golgi SNAP receptor complex member 2
chr3_-_123620496 0.25 ENST00000578202.1
myosin light chain kinase
chr3_-_120285215 0.25 ENST00000464295.6
G protein-coupled receptor 156
chr6_+_26402237 0.25 ENST00000476549.6
ENST00000450085.6
ENST00000425234.6
ENST00000427334.5
ENST00000506698.1
ENST00000289361.11
butyrophilin subfamily 3 member A1
chr19_+_55600277 0.25 ENST00000301073.4
zinc finger protein 524
chr5_-_124746630 0.25 ENST00000513986.2
zinc finger protein 608
chr17_+_18183052 0.25 ENST00000541285.1
alkB homolog 5, RNA demethylase
chr2_-_189179754 0.24 ENST00000374866.9
ENST00000618828.1
collagen type V alpha 2 chain
chr6_-_46325641 0.24 ENST00000330430.10
ENST00000405162.2
regulator of calcineurin 2
chr7_-_56034133 0.24 ENST00000421626.5
phosphoserine phosphatase
chr8_-_48921419 0.24 ENST00000020945.4
snail family transcriptional repressor 2
chr1_+_70411180 0.24 ENST00000411986.6
cystathionine gamma-lyase
chr1_+_86547070 0.24 ENST00000370563.3
chloride channel accessory 4
chr15_+_41621134 0.24 ENST00000566718.6
MAX dimerization protein MGA
chr11_-_11353241 0.24 ENST00000528848.3
casein kinase 2 alpha 3
chr11_+_35180279 0.24 ENST00000531873.5
CD44 molecule (Indian blood group)
chr12_-_10807286 0.24 ENST00000240615.3
taste 2 receptor member 8
chr1_+_174275093 0.24 ENST00000367690.5
RAB GTPase activating protein 1 like
chr8_-_89984231 0.24 ENST00000517337.1
ENST00000409330.5
nibrin
chr6_+_29111560 0.24 ENST00000377169.2
olfactory receptor family 2 subfamily J member 3
chr3_+_111999326 0.24 ENST00000494932.1
transgelin 3
chr18_+_52752032 0.24 ENST00000412726.5
ENST00000578080.1
ENST00000582875.1
DCC netrin 1 receptor
chr1_-_32964685 0.24 ENST00000373456.11
ENST00000356990.9
ENST00000235150.5
ring finger protein 19B
chr17_-_79950828 0.23 ENST00000572862.5
ENST00000573782.5
ENST00000574427.1
ENST00000570373.5
ENST00000340848.11
ENST00000576768.5
TBC1 domain family member 16
chr10_-_88952763 0.23 ENST00000224784.10
actin alpha 2, smooth muscle
chr11_-_18236795 0.23 ENST00000278222.7
serum amyloid A4, constitutive
chr18_+_34976928 0.23 ENST00000591734.5
ENST00000413393.5
ENST00000589180.5
ENST00000587359.5
microtubule associated protein RP/EB family member 2
chr5_+_173918186 0.23 ENST00000657000.1
cytoplasmic polyadenylation element binding protein 4
chr8_-_130386864 0.23 ENST00000521426.5
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr1_-_152159227 0.23 ENST00000316073.3
repetin
chr11_+_313391 0.23 ENST00000680802.1
ENST00000528780.5
ENST00000681761.1
ENST00000681821.1
ENST00000328221.5
interferon induced transmembrane protein 1
chr9_+_470291 0.23 ENST00000382303.5
KN motif and ankyrin repeat domains 1
chr11_-_124315099 0.23 ENST00000641897.1
olfactory receptor family 8 subfamily D member 1
chr15_-_55270874 0.23 ENST00000567380.5
ENST00000565972.5
ENST00000569493.5
RAB27A, member RAS oncogene family
chr15_-_55270383 0.22 ENST00000396307.6
RAB27A, member RAS oncogene family
chr6_+_41053194 0.22 ENST00000244669.3
apolipoprotein B mRNA editing enzyme catalytic subunit 2
chr16_-_28623560 0.22 ENST00000350842.8
sulfotransferase family 1A member 1
chr7_-_93226449 0.22 ENST00000394468.7
ENST00000453812.2
HEPACAM family member 2
chr7_+_151341764 0.22 ENST00000413040.7
ENST00000470229.6
ENST00000568733.6
negative regulator of ubiquitin like proteins 1
chr11_-_60243103 0.22 ENST00000651255.1
membrane spanning 4-domains A4E
chr1_-_92486916 0.22 ENST00000294702.6
growth factor independent 1 transcriptional repressor
chr1_-_89126066 0.22 ENST00000370466.4
guanylate binding protein 2
chr11_-_4608226 0.22 ENST00000300747.10
ENST00000526337.5
tripartite motif containing 68
chr15_+_89575492 0.22 ENST00000560985.5
TOPBP1 interacting checkpoint and replication regulator

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0034769 basement membrane disassembly(GO:0034769)
0.3 0.8 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.2 0.6 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) mast cell proliferation(GO:0070662)
0.2 0.5 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2 0.7 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.2 0.5 GO:0085032 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.2 1.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.2 1.7 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.4 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.1 0.4 GO:0046967 cytosol to ER transport(GO:0046967)
0.1 0.4 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.7 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.9 GO:1902731 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.1 0.2 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.1 0.3 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 0.5 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.5 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.5 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 0.3 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.1 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.1 1.1 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.6 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.4 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 0.3 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.1 0.5 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.9 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.4 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.1 0.2 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.3 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 0.4 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 1.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.2 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
0.1 0.5 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.3 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.1 0.5 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1 0.2 GO:0061011 hepatic duct development(GO:0061011)
0.1 0.6 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.2 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.1 0.3 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.1 0.2 GO:1903487 regulation of lactation(GO:1903487)
0.1 0.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.5 GO:0030242 pexophagy(GO:0030242)
0.1 1.0 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.3 GO:0035617 stress granule disassembly(GO:0035617)
0.1 0.2 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.1 0.2 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.6 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.3 GO:0008218 bioluminescence(GO:0008218)
0.1 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.2 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.1 0.2 GO:2000329 negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.1 0.4 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.5 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:1904823 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.2 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 1.2 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.4 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.4 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.2 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.2 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.0 0.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.6 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.2 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.2 GO:0030035 microspike assembly(GO:0030035)
0.0 0.3 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.0 0.8 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.5 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 1.0 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.2 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.0 0.2 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.1 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 0.2 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.2 GO:0015692 lead ion transport(GO:0015692)
0.0 0.1 GO:0016108 tetraterpenoid metabolic process(GO:0016108) carotenoid metabolic process(GO:0016116) carotene catabolic process(GO:0016121) xanthophyll metabolic process(GO:0016122) terpene catabolic process(GO:0046247)
0.0 0.1 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.2 GO:0060356 leucine import(GO:0060356)
0.0 0.1 GO:0009720 detection of hormone stimulus(GO:0009720)
0.0 0.2 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0 0.1 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 1.9 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.6 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.1 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.0 0.1 GO:0036215 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.4 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.2 GO:0003350 pulmonary myocardium development(GO:0003350)
0.0 0.1 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.0 0.3 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 0.1 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.0 0.2 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.1 GO:0042495 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.0 0.7 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.0 0.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.3 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.1 GO:1901993 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.1 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0 0.3 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.4 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.1 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.0 GO:0002125 maternal aggressive behavior(GO:0002125)
0.0 0.1 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.1 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.5 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.2 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.1 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
0.0 0.1 GO:0042335 cuticle development(GO:0042335)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0090365 regulation of mRNA modification(GO:0090365)
0.0 0.5 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 1.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.2 GO:0060467 negative regulation of fertilization(GO:0060467)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.8 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.0 0.1 GO:0032621 interleukin-18 production(GO:0032621)
0.0 0.1 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.1 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.2 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.1 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.0 2.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.0 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.1 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
0.0 0.0 GO:1901355 response to rapamycin(GO:1901355)
0.0 0.1 GO:0097272 ammonia homeostasis(GO:0097272)
0.0 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.1 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
0.0 0.5 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.0 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.0 0.3 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.1 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.1 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0 0.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.1 GO:0033606 B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.2 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.0 0.1 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.6 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.0 0.1 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.1 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.2 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.5 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.2 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0070859 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.0 0.2 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.6 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.1 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.2 GO:0070170 regulation of tooth mineralization(GO:0070170)
0.0 0.2 GO:1904180 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.2 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0019255 glucosamine metabolic process(GO:0006041) glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.0 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397) positive regulation of hepatocyte proliferation(GO:2000347)
0.0 0.0 GO:0072641 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024) regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905031)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.1 GO:0002912 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.0 0.0 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 2.3 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.1 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.0 0.0 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.0 1.1 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.3 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.0 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.2 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.0 GO:1990523 bone regeneration(GO:1990523)
0.0 0.0 GO:0039023 positive regulation of polarized epithelial cell differentiation(GO:0030862) pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
0.0 0.0 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.0 0.1 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.2 GO:0071476 cellular hypotonic response(GO:0071476)
0.0 0.1 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.0 0.3 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.2 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.9 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.0 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 0.0 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.3 GO:0008228 opsonization(GO:0008228)
0.0 0.0 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.1 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.1 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.1 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.0 GO:0007174 epidermal growth factor catabolic process(GO:0007174)
0.0 0.1 GO:0061358 adenylate cyclase-inhibiting opioid receptor signaling pathway(GO:0031635) negative regulation of Wnt protein secretion(GO:0061358)
0.0 0.1 GO:0035962 response to interleukin-13(GO:0035962)
0.0 0.2 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.2 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0015820 leucine transport(GO:0015820)
0.0 0.0 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.0 0.0 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.1 GO:0052564 response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.0 0.1 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.1 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.0 0.2 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.0 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.1 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.0 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.0 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.2 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.2 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.1 GO:0001554 luteolysis(GO:0001554)
0.0 0.2 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.1 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.0 0.0 GO:1901859 base-excision repair, DNA ligation(GO:0006288) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.0 0.0 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.0 GO:0006545 glycine biosynthetic process(GO:0006545) cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0 0.1 GO:0007320 insemination(GO:0007320)
0.0 0.3 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.1 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0 0.0 GO:1903936 cellular response to sodium arsenite(GO:1903936)
0.0 0.2 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 GO:0036021 endolysosome lumen(GO:0036021)
0.2 0.6 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.5 GO:0097179 protease inhibitor complex(GO:0097179)
0.1 0.3 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 1.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 2.0 GO:0032433 filopodium tip(GO:0032433)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.2 GO:0033565 ESCRT-0 complex(GO:0033565)
0.1 0.8 GO:0005879 axonemal microtubule(GO:0005879)
0.1 1.6 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 1.0 GO:0016013 syntrophin complex(GO:0016013)
0.1 0.4 GO:0042825 TAP complex(GO:0042825)
0.1 1.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.4 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.2 GO:0000811 GINS complex(GO:0000811)
0.0 0.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.6 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.2 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.0 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.4 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0032010 phagolysosome(GO:0032010)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.5 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.1 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.3 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.2 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 1.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.3 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.0 GO:0071752 dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.1 GO:0032302 MutSbeta complex(GO:0032302)
0.0 0.2 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 0.2 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 0.0 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.0 1.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.0 GO:0045259 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.0 0.6 GO:0001533 cornified envelope(GO:0001533)
0.0 0.0 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.7 GO:0002102 podosome(GO:0002102)
0.0 0.7 GO:0031941 filamentous actin(GO:0031941)
0.0 0.0 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.0 GO:0042272 nuclear RNA export factor complex(GO:0042272)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.3 0.8 GO:0031862 prostanoid receptor binding(GO:0031862)
0.2 0.2 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.1 0.4 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.1 0.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.3 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 0.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.7 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.3 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.4 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.1 0.3 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.1 0.9 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 2.8 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.7 GO:0004064 arylesterase activity(GO:0004064)
0.1 0.5 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.1 0.2 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.2 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.1 0.8 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.5 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.5 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.5 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 1.0 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.0 0.1 GO:0036505 prosaposin receptor activity(GO:0036505)
0.0 0.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.1 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 1.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.1 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 0.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0070728 leucine binding(GO:0070728)
0.0 0.2 GO:0050473 arachidonate 15-lipoxygenase activity(GO:0050473)
0.0 0.2 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.5 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.2 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.2 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.1 GO:0003973 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.0 0.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.9 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.2 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 1.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.0 0.0 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 1.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.0 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.2 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 0.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.1 GO:0001132 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.8 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0000406 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.7 GO:0005549 odorant binding(GO:0005549)
0.0 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 2.6 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.6 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.0 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.6 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.6 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.0 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.0 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.0 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.2 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.0 0.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0038047 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.3 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.0 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.1 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.0 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.0 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0 0.6 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.0 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.3 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.0 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 1.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.0 0.8 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.0 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.0 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.6 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.1 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.0 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.0 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.5 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.7 PID ARF 3PATHWAY Arf1 pathway
0.0 1.2 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.0 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.0 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.1 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 2.1 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.1 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 4.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.7 PID BMP PATHWAY BMP receptor signaling
0.0 0.4 ST GAQ PATHWAY G alpha q Pathway
0.0 0.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 0.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 2.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.6 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 3.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.2 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.7 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.1 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.2 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway