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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for HOXB4_LHX9

Z-value: 0.52

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Transcription factors associated with HOXB4_LHX9

Gene Symbol Gene ID Gene Info
HOXB4
ENSG00000182742.6 HOXB4
LHX9
ENSG00000143355.16 LHX9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX9hg38_v1_chr1_+_197912462_1979125050.242.4e-01Click!
HOXB4hg38_v1_chr17_-_48578341_485783560.125.8e-01Click!

Activity profile of HOXB4_LHX9 motif

Sorted Z-values of HOXB4_LHX9 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB4_LHX9

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_+_155666718 1.35 ENST00000621234.4
ENST00000511108.5
GUCY1A1
guanylate cyclase 1 soluble subunit alpha 1
chr12_-_9869345 1.11 ENST00000228438.3
CLEC2B
C-type lectin domain family 2 member B
chr18_+_44700796 1.10 ENST00000677130.1
SETBP1
SET binding protein 1
chr16_-_66549839 1.02 ENST00000527800.6
ENST00000677555.1
ENST00000563369.6
TK2
thymidine kinase 2
chr16_-_66550091 1.00 ENST00000564917.5
ENST00000677420.1
TK2
thymidine kinase 2
chr16_-_66550005 0.95 ENST00000527284.6
TK2
thymidine kinase 2
chr3_-_142029108 0.95 ENST00000497579.5
TFDP2
transcription factor Dp-2
chr9_+_72577939 0.88 ENST00000645773.1
TMC1
transmembrane channel like 1
chr11_+_71527267 0.88 ENST00000398536.6
KRTAP5-7
keratin associated protein 5-7
chr4_-_139280179 0.86 ENST00000398955.2
MGARP
mitochondria localized glutamic acid rich protein
chr13_-_109786567 0.76 ENST00000375856.5
IRS2
insulin receptor substrate 2
chr11_-_63608542 0.72 ENST00000540943.1
PLAAT3
phospholipase A and acyltransferase 3
chr5_+_1225379 0.70 ENST00000324642.4
SLC6A18
solute carrier family 6 member 18
chr2_+_90038848 0.64 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr7_+_1044542 0.64 ENST00000444847.2
GPR146
G protein-coupled receptor 146
chr17_+_69502397 0.59 ENST00000613873.4
ENST00000589647.5
MAP2K6
mitogen-activated protein kinase kinase 6
chr20_-_35147285 0.57 ENST00000374491.3
ENST00000374492.8
EDEM2
ER degradation enhancing alpha-mannosidase like protein 2
chr15_-_19988117 0.56 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr6_+_130018565 0.54 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL3
L3MBTL histone methyl-lysine binding protein 3
chr9_+_72577369 0.53 ENST00000651183.1
TMC1
transmembrane channel like 1
chr5_+_113513674 0.51 ENST00000161863.9
ENST00000515883.5
YTHDC2
YTH domain containing 2
chr12_+_38316753 0.51 ENST00000551464.1
ENST00000308742.9
ALG10B
ALG10 alpha-1,2-glucosyltransferase B
chr4_-_89836213 0.50 ENST00000618500.4
ENST00000508895.5
SNCA
synuclein alpha
chr16_-_66550142 0.47 ENST00000417693.8
ENST00000299697.12
ENST00000451102.7
TK2
thymidine kinase 2
chr4_+_133149278 0.46 ENST00000264360.7
PCDH10
protocadherin 10
chr11_+_7605719 0.45 ENST00000530181.5
PPFIBP2
PPFIA binding protein 2
chr20_-_57690624 0.45 ENST00000414037.5
PMEPA1
prostate transmembrane protein, androgen induced 1
chr7_-_150323489 0.42 ENST00000683684.1
ENST00000478393.5
ACTR3C
actin related protein 3C
chr7_+_150323239 0.41 ENST00000323078.7
ENST00000493307.1
ENST00000359623.9
LRRC61
leucine rich repeat containing 61
chr4_-_137532452 0.40 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
PCDH18
protocadherin 18
chr14_+_30577752 0.40 ENST00000547532.5
ENST00000555429.1
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr17_+_41237998 0.40 ENST00000254072.7
KRTAP9-8
keratin associated protein 9-8
chr3_-_142000353 0.39 ENST00000499676.5
TFDP2
transcription factor Dp-2
chr4_+_89901979 0.39 ENST00000508372.1
MMRN1
multimerin 1
chr17_+_68515399 0.38 ENST00000588188.6
PRKAR1A
protein kinase cAMP-dependent type I regulatory subunit alpha
chr5_-_90474765 0.38 ENST00000316610.7
MBLAC2
metallo-beta-lactamase domain containing 2
chr2_+_201182873 0.37 ENST00000360132.7
CASP10
caspase 10
chr7_+_102912983 0.37 ENST00000339431.9
ENST00000249377.4
LRRC17
leucine rich repeat containing 17
chr6_+_47656436 0.36 ENST00000507065.5
ENST00000296862.5
ADGRF2
adhesion G protein-coupled receptor F2
chr6_-_110179995 0.36 ENST00000392586.5
ENST00000419252.1
ENST00000359451.6
ENST00000392588.5
WASF1
WASP family member 1
chr7_+_107583919 0.35 ENST00000491150.5
BCAP29
B cell receptor associated protein 29
chr8_-_92966081 0.35 ENST00000517858.5
ENST00000378861.9
TRIQK
triple QxxK/R motif containing
chr8_-_30812867 0.34 ENST00000518243.5
PPP2CB
protein phosphatase 2 catalytic subunit beta
chr20_-_31390483 0.34 ENST00000376315.2
DEFB119
defensin beta 119
chr18_-_55423757 0.33 ENST00000675707.1
TCF4
transcription factor 4
chr8_-_92966129 0.33 ENST00000522925.5
ENST00000522903.5
ENST00000537541.1
ENST00000521988.6
ENST00000518748.5
ENST00000519069.5
TRIQK
triple QxxK/R motif containing
chr8_-_92966105 0.33 ENST00000524037.5
ENST00000520430.5
ENST00000521617.5
ENST00000523580.5
TRIQK
triple QxxK/R motif containing
chr2_+_66435116 0.33 ENST00000272369.14
ENST00000560281.6
MEIS1
Meis homeobox 1
chr12_-_10826358 0.32 ENST00000240619.2
TAS2R10
taste 2 receptor member 10
chr10_+_99732211 0.32 ENST00000370476.10
ENST00000370472.4
CUTC
cutC copper transporter
chr7_+_116222804 0.32 ENST00000393481.6
TES
testin LIM domain protein
chr5_+_154941063 0.32 ENST00000523037.6
ENST00000265229.12
ENST00000439747.7
ENST00000522038.5
MRPL22
mitochondrial ribosomal protein L22
chr1_-_201171545 0.32 ENST00000367333.6
TMEM9
transmembrane protein 9
chr1_+_77918128 0.31 ENST00000342754.5
NEXN
nexilin F-actin binding protein
chr11_-_69819410 0.31 ENST00000334134.4
FGF3
fibroblast growth factor 3
chr11_-_122116215 0.31 ENST00000560104.2
BLID
BH3-like motif containing, cell death inducer
chr19_-_35812838 0.30 ENST00000653904.2
PRODH2
proline dehydrogenase 2
chr13_+_76948500 0.30 ENST00000377462.6
ACOD1
aconitate decarboxylase 1
chr19_-_51417700 0.30 ENST00000529627.1
ENST00000439889.6
SIGLEC10
sialic acid binding Ig like lectin 10
chr3_+_158801926 0.29 ENST00000622669.4
ENST00000392813.8
ENST00000415822.8
ENST00000651862.1
ENST00000264266.12
MFSD1
major facilitator superfamily domain containing 1
chr11_-_125111708 0.28 ENST00000531909.5
ENST00000529530.1
TMEM218
transmembrane protein 218
chr6_+_130421086 0.28 ENST00000545622.5
TMEM200A
transmembrane protein 200A
chrX_-_18672101 0.28 ENST00000379984.4
RS1
retinoschisin 1
chr16_-_66550112 0.28 ENST00000544898.6
ENST00000620035.5
ENST00000545043.6
TK2
thymidine kinase 2
chr11_+_92969651 0.27 ENST00000257068.3
ENST00000528076.1
MTNR1B
melatonin receptor 1B
chr9_+_72577788 0.27 ENST00000645208.2
TMC1
transmembrane channel like 1
chr5_-_74641419 0.27 ENST00000618628.4
ENST00000510316.5
ENST00000508331.1
ENC1
ectodermal-neural cortex 1
chr9_-_74952904 0.26 ENST00000376854.6
C9orf40
chromosome 9 open reading frame 40
chr10_+_96129707 0.26 ENST00000316045.9
ZNF518A
zinc finger protein 518A
chr12_+_26195647 0.25 ENST00000535504.1
SSPN
sarcospan
chr3_-_185821092 0.25 ENST00000421047.3
IGF2BP2
insulin like growth factor 2 mRNA binding protein 2
chr13_-_52011337 0.25 ENST00000400366.6
ENST00000400370.8
ENST00000634844.1
ENST00000673772.1
ENST00000418097.7
ENST00000242839.10
ENST00000344297.9
ENST00000448424.7
ATP7B
ATPase copper transporting beta
chr8_-_100559702 0.25 ENST00000520311.5
ENST00000520552.5
ENST00000521345.1
ENST00000523000.5
ENST00000335659.7
ENST00000358990.3
ENST00000519597.5
ANKRD46
ankyrin repeat domain 46
chr2_+_201183120 0.25 ENST00000272879.9
ENST00000286186.11
ENST00000374650.7
ENST00000346817.9
ENST00000313728.11
ENST00000448480.1
CASP10
caspase 10
chr12_+_64404338 0.25 ENST00000332707.10
XPOT
exportin for tRNA
chr3_+_42979281 0.25 ENST00000488863.5
ENST00000430121.3
GASK1A
golgi associated kinase 1A
chr2_-_182242031 0.25 ENST00000358139.6
PDE1A
phosphodiesterase 1A
chr6_+_29461440 0.24 ENST00000396792.2
OR2H1
olfactory receptor family 2 subfamily H member 1
chr20_-_31390580 0.24 ENST00000339144.3
ENST00000376321.4
DEFB119
defensin beta 119
chr19_+_49513353 0.24 ENST00000596975.5
FCGRT
Fc fragment of IgG receptor and transporter
chr17_-_55722857 0.24 ENST00000424486.3
TMEM100
transmembrane protein 100
chrX_+_43656289 0.24 ENST00000338702.4
MAOA
monoamine oxidase A
chrX_-_103255117 0.24 ENST00000372685.8
ENST00000360000.8
ENST00000451678.1
TCEAL8
transcription elongation factor A like 8
chr15_+_94355956 0.24 ENST00000557742.1
MCTP2
multiple C2 and transmembrane domain containing 2
chr17_-_445939 0.24 ENST00000329099.4
RFLNB
refilin B
chr5_+_175861628 0.24 ENST00000509837.5
CPLX2
complexin 2
chr6_-_38703066 0.23 ENST00000373365.5
GLO1
glyoxalase I
chr1_+_42825548 0.23 ENST00000372514.7
ERMAP
erythroblast membrane associated protein (Scianna blood group)
chr12_+_119668109 0.23 ENST00000229328.10
ENST00000630317.1
PRKAB1
protein kinase AMP-activated non-catalytic subunit beta 1
chr6_+_29111560 0.23 ENST00000377169.2
OR2J3
olfactory receptor family 2 subfamily J member 3
chr1_+_152811971 0.23 ENST00000360090.4
LCE1B
late cornified envelope 1B
chr6_+_28124596 0.23 ENST00000340487.5
ZSCAN16
zinc finger and SCAN domain containing 16
chr3_+_45886501 0.23 ENST00000395963.2
CCR9
C-C motif chemokine receptor 9
chr5_-_126595237 0.23 ENST00000637206.1
ENST00000553117.5
ALDH7A1
aldehyde dehydrogenase 7 family member A1
chr14_-_67412112 0.22 ENST00000216446.9
PLEK2
pleckstrin 2
chr19_-_43883964 0.22 ENST00000587539.2
ZNF404
zinc finger protein 404
chr2_-_88979016 0.22 ENST00000390247.2
IGKV3-7
immunoglobulin kappa variable 3-7 (non-functional)
chr2_+_90172802 0.22 ENST00000390277.3
IGKV3D-11
immunoglobulin kappa variable 3D-11
chr6_-_110815152 0.22 ENST00000413605.6
CDK19
cyclin dependent kinase 19
chr3_-_157503375 0.22 ENST00000362010.7
VEPH1
ventricular zone expressed PH domain containing 1
chr16_+_3135121 0.22 ENST00000576416.5
ENST00000416391.6
ZNF213
zinc finger protein 213
chr12_+_34022462 0.21 ENST00000538927.1
ENST00000266483.7
ALG10
ALG10 alpha-1,2-glucosyltransferase
chr9_+_93234923 0.21 ENST00000411624.5
WNK2
WNK lysine deficient protein kinase 2
chr4_+_94207596 0.21 ENST00000359052.8
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr1_+_248013660 0.21 ENST00000355281.2
OR2L5
olfactory receptor family 2 subfamily L member 5
chr3_-_157503339 0.21 ENST00000392833.6
VEPH1
ventricular zone expressed PH domain containing 1
chrX_+_10158448 0.21 ENST00000380829.5
ENST00000421085.7
ENST00000674669.1
ENST00000454850.1
CLCN4
chloride voltage-gated channel 4
chr1_-_13116854 0.21 ENST00000621994.3
HNRNPCL2
heterogeneous nuclear ribonucleoprotein C like 2
chr17_+_18183052 0.21 ENST00000541285.1
ALKBH5
alkB homolog 5, RNA demethylase
chr4_-_149815826 0.21 ENST00000636793.2
ENST00000636414.1
IQCM
IQ motif containing M
chr17_+_50746534 0.20 ENST00000511974.5
LUC7L3
LUC7 like 3 pre-mRNA splicing factor
chrX_+_108091752 0.20 ENST00000457035.5
ENST00000372232.8
ATG4A
autophagy related 4A cysteine peptidase
chr14_-_106038355 0.20 ENST00000390597.3
IGHV2-5
immunoglobulin heavy variable 2-5
chr1_-_212791762 0.20 ENST00000626725.1
ENST00000366977.8
ENST00000366976.3
NSL1
NSL1 component of MIS12 kinetochore complex
chr2_+_90234809 0.19 ENST00000443397.5
IGKV3D-7
immunoglobulin kappa variable 3D-7
chr6_-_110815408 0.19 ENST00000368911.8
CDK19
cyclin dependent kinase 19
chr15_+_58410543 0.19 ENST00000356113.10
ENST00000414170.7
LIPC
lipase C, hepatic type
chrX_+_108091665 0.19 ENST00000345734.7
ATG4A
autophagy related 4A cysteine peptidase
chr14_-_106211453 0.19 ENST00000390606.3
IGHV3-20
immunoglobulin heavy variable 3-20
chr18_+_62539511 0.19 ENST00000586834.1
ZCCHC2
zinc finger CCHC-type containing 2
chr2_-_27663594 0.19 ENST00000337768.10
ENST00000405491.5
ENST00000464789.2
ENST00000406540.5
SUPT7L
SPT7 like, STAGA complex subunit gamma
chr6_-_53510445 0.19 ENST00000509541.5
GCLC
glutamate-cysteine ligase catalytic subunit
chr6_-_52994248 0.19 ENST00000457564.1
ENST00000370960.5
GSTA4
glutathione S-transferase alpha 4
chr2_-_27663817 0.18 ENST00000404798.6
SUPT7L
SPT7 like, STAGA complex subunit gamma
chr1_-_160954801 0.18 ENST00000368029.4
ITLN2
intelectin 2
chr14_-_106470788 0.18 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chrX_-_72239022 0.18 ENST00000373657.2
ENST00000334463.4
ERCC6L
ERCC excision repair 6 like, spindle assembly checkpoint helicase
chr9_-_96778053 0.18 ENST00000375231.5
ENST00000223428.9
ZNF510
zinc finger protein 510
chr1_+_155308930 0.18 ENST00000465559.5
ENST00000612683.1
FDPS
farnesyl diphosphate synthase
chr4_+_87608529 0.18 ENST00000651931.1
DSPP
dentin sialophosphoprotein
chr11_-_129024157 0.17 ENST00000392657.7
ARHGAP32
Rho GTPase activating protein 32
chr1_+_155308748 0.17 ENST00000611010.4
ENST00000447866.5
ENST00000368356.9
ENST00000467076.5
ENST00000491013.5
ENST00000356657.10
FDPS
farnesyl diphosphate synthase
chr9_+_122371014 0.17 ENST00000362012.7
PTGS1
prostaglandin-endoperoxide synthase 1
chr5_+_36151989 0.17 ENST00000274254.9
SKP2
S-phase kinase associated protein 2
chr7_+_117014881 0.17 ENST00000422922.5
ENST00000432298.5
ST7
suppression of tumorigenicity 7
chr16_+_3134923 0.17 ENST00000574902.5
ENST00000396878.8
ZNF213
zinc finger protein 213
chr12_+_101594849 0.17 ENST00000547405.5
ENST00000452455.6
ENST00000392934.7
ENST00000547509.5
ENST00000361685.6
ENST00000549145.5
ENST00000361466.7
ENST00000553190.5
ENST00000545503.6
ENST00000536007.5
ENST00000541119.5
ENST00000551300.5
ENST00000550270.1
MYBPC1
myosin binding protein C1
chr6_+_29550407 0.16 ENST00000641137.1
OR2I1P
olfactory receptor family 2 subfamily I member 1 pseudogene
chr3_+_39383337 0.16 ENST00000650617.1
ENST00000431510.1
ENST00000645630.1
SLC25A38
solute carrier family 25 member 38
chrX_+_77910656 0.16 ENST00000343533.9
ENST00000341514.11
ENST00000645454.1
ENST00000642651.1
ENST00000644362.1
ATP7A
PGK1
ATPase copper transporting alpha
phosphoglycerate kinase 1
chr17_+_18183803 0.16 ENST00000399138.5
ALKBH5
alkB homolog 5, RNA demethylase
chr5_+_140841183 0.16 ENST00000378123.4
ENST00000531613.2
PCDHA8
protocadherin alpha 8
chr2_+_233729042 0.16 ENST00000482026.6
UGT1A3
UDP glucuronosyltransferase family 1 member A3
chr13_-_75366973 0.16 ENST00000648194.1
TBC1D4
TBC1 domain family member 4
chr14_-_94323324 0.16 ENST00000341584.4
SERPINA6
serpin family A member 6
chr13_+_35476740 0.16 ENST00000537702.5
NBEA
neurobeachin
chr10_+_92691813 0.16 ENST00000472590.6
HHEX
hematopoietically expressed homeobox
chr15_-_55408245 0.16 ENST00000563171.5
ENST00000425574.7
ENST00000442196.8
ENST00000564092.1
CCPG1
cell cycle progression 1
chr19_+_55836532 0.15 ENST00000301295.11
NLRP4
NLR family pyrin domain containing 4
chrX_+_37780049 0.15 ENST00000378588.5
CYBB
cytochrome b-245 beta chain
chr5_+_36152077 0.15 ENST00000546211.6
ENST00000620197.5
ENST00000678270.1
ENST00000679015.1
ENST00000678580.1
ENST00000274255.11
ENST00000508514.5
SKP2
S-phase kinase associated protein 2
chr17_-_41586887 0.15 ENST00000167586.7
KRT14
keratin 14
chr2_-_89027700 0.15 ENST00000483158.1
IGKV3-11
immunoglobulin kappa variable 3-11
chr6_-_109381739 0.15 ENST00000504373.2
CD164
CD164 molecule
chr2_+_87338511 0.15 ENST00000421835.2
IGKV3OR2-268
immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr4_+_157076119 0.15 ENST00000541722.5
ENST00000264428.9
ENST00000512619.5
GLRB
glycine receptor beta
chr19_+_11374658 0.14 ENST00000674460.1
ENST00000312423.4
SWSAP1
SWIM-type zinc finger 7 associated protein 1
chr2_-_160200289 0.14 ENST00000409872.1
ITGB6
integrin subunit beta 6
chr8_-_30812773 0.14 ENST00000221138.9
PPP2CB
protein phosphatase 2 catalytic subunit beta
chr19_-_4558417 0.14 ENST00000586965.1
SEMA6B
semaphorin 6B
chr6_+_110180418 0.14 ENST00000368930.5
ENST00000307731.2
CDC40
cell division cycle 40
chr8_-_7430348 0.14 ENST00000318124.3
DEFB103B
defensin beta 103B
chr12_-_23584600 0.14 ENST00000396007.6
SOX5
SRY-box transcription factor 5
chr2_-_142131004 0.14 ENST00000434794.1
ENST00000389484.8
LRP1B
LDL receptor related protein 1B
chr14_+_56117702 0.13 ENST00000559044.5
PELI2
pellino E3 ubiquitin protein ligase family member 2
chrX_+_7219431 0.13 ENST00000674499.1
ENST00000217961.5
STS
steroid sulfatase
chr2_+_132416795 0.13 ENST00000329321.4
GPR39
G protein-coupled receptor 39
chr10_-_30629741 0.13 ENST00000647634.2
ENST00000375318.4
LYZL2
lysozyme like 2
chr3_-_149576203 0.13 ENST00000472417.1
WWTR1
WW domain containing transcription regulator 1
chrX_+_85003863 0.13 ENST00000373173.7
APOOL
apolipoprotein O like
chr1_+_27934980 0.13 ENST00000373894.8
SMPDL3B
sphingomyelin phosphodiesterase acid like 3B
chr2_-_201739205 0.13 ENST00000681558.1
ENST00000681495.1
ALS2
alsin Rho guanine nucleotide exchange factor ALS2
chr4_+_75556048 0.13 ENST00000616557.1
ENST00000435974.2
ENST00000311623.9
ODAPH
odontogenesis associated phosphoprotein
chr10_+_87357720 0.13 ENST00000412718.3
ENST00000381697.7
NUTM2D
NUT family member 2D
chr2_+_102473219 0.13 ENST00000295269.5
SLC9A4
solute carrier family 9 member A4
chr17_-_47189176 0.13 ENST00000531206.5
ENST00000527547.5
ENST00000575483.5
ENST00000066544.8
CDC27
cell division cycle 27
chr17_+_50746614 0.13 ENST00000513969.5
ENST00000503728.1
LUC7L3
LUC7 like 3 pre-mRNA splicing factor
chr2_+_27663441 0.13 ENST00000326019.10
ENST00000613058.4
SLC4A1AP
solute carrier family 4 member 1 adaptor protein
chr17_+_32021005 0.13 ENST00000327564.11
ENST00000584368.5
ENST00000394713.7
ENST00000341671.11
LRRC37B
leucine rich repeat containing 37B
chr2_-_20823048 0.12 ENST00000402479.6
ENST00000237822.8
ENST00000626491.2
ENST00000432947.1
ENST00000403006.6
ENST00000419825.2
ENST00000381090.7
ENST00000412261.5
ENST00000619656.4
ENST00000541941.5
ENST00000440866.6
ENST00000435420.6
LDAH
lipid droplet associated hydrolase
chr20_+_45416551 0.12 ENST00000639292.1
PIGT
phosphatidylinositol glycan anchor biosynthesis class T
chr14_-_74084393 0.12 ENST00000350259.8
ENST00000553458.6
ALDH6A1
aldehyde dehydrogenase 6 family member A1
chr6_+_110180116 0.12 ENST00000368932.5
CDC40
cell division cycle 40
chr13_+_77741160 0.12 ENST00000314070.9
ENST00000351546.7
SLAIN1
SLAIN motif family member 1
chr22_+_39901075 0.12 ENST00000344138.9
GRAP2
GRB2 related adaptor protein 2
chr1_-_77219399 0.12 ENST00000359130.1
ENST00000370812.8
ENST00000445065.5
PIGK
phosphatidylinositol glycan anchor biosynthesis class K
chr2_+_27663880 0.12 ENST00000618046.4
ENST00000613517.4
SLC4A1AP
solute carrier family 4 member 1 adaptor protein
chr19_+_49513154 0.12 ENST00000426395.7
ENST00000600273.5
ENST00000599988.5
FCGRT
Fc fragment of IgG receptor and transporter
chr4_-_99219230 0.11 ENST00000394897.5
ENST00000508558.1
ENST00000394899.6
ADH6
alcohol dehydrogenase 6 (class V)
chr20_+_58907981 0.11 ENST00000656419.1
GNAS
GNAS complex locus
chr13_-_35855758 0.11 ENST00000615680.4
DCLK1
doublecortin like kinase 1
chr15_+_48191648 0.11 ENST00000646012.1
ENST00000561127.5
ENST00000647546.1
ENST00000559641.5
ENST00000417307.3
SLC12A1
CTXN2
solute carrier family 12 member 1
cortexin 2
chr7_-_36985060 0.11 ENST00000396040.6
ELMO1
engulfment and cell motility 1
chr2_+_233917371 0.11 ENST00000324695.9
ENST00000433712.6
TRPM8
transient receptor potential cation channel subfamily M member 8
chr18_-_35290184 0.11 ENST00000589178.5
ENST00000592278.1
ENST00000333206.10
ENST00000592211.1
ENST00000420878.7
ENST00000610712.1
ENST00000586922.2
ZSCAN30
ENSG00000268573.1
zinc finger and SCAN domain containing 30
novel transcript
chr7_-_87220567 0.11 ENST00000433078.5
TMEM243
transmembrane protein 243
chr19_+_55857437 0.11 ENST00000587891.5
NLRP4
NLR family pyrin domain containing 4
chr17_+_1771688 0.11 ENST00000572048.1
ENST00000573763.1
SERPINF1
serpin family F member 1
chr10_-_13001705 0.10 ENST00000378825.5
CCDC3
coiled-coil domain containing 3
chr3_-_149377637 0.10 ENST00000305366.8
TM4SF1
transmembrane 4 L six family member 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.7 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.2 0.6 GO:0072709 cellular response to sorbitol(GO:0072709)
0.2 0.6 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.2 0.9 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.2 1.6 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.4 GO:0060003 copper ion export(GO:0060003)
0.1 0.8 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 0.4 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.1 0.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.4 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.5 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.1 0.5 GO:0051622 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.2 GO:0061182 negative regulation of chondrocyte development(GO:0061182)
0.1 0.2 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.1 0.3 GO:0033384 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.1 0.4 GO:0051697 protein delipidation(GO:0051697)
0.1 0.3 GO:0072573 propionate metabolic process(GO:0019541) cellular response to progesterone stimulus(GO:0071393) tolerance induction to lipopolysaccharide(GO:0072573)
0.1 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.2 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.1 0.2 GO:0036233 glycine import(GO:0036233)
0.1 0.3 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.2 GO:0061011 hepatic duct development(GO:0061011)
0.1 0.2 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.2 GO:0097069 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.0 0.5 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.4 GO:0048539 bone marrow development(GO:0048539)
0.0 0.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.1 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.0 0.1 GO:0039008 pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
0.0 0.1 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.0 0.1 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 1.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.2 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 0.4 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.4 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.1 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.1 GO:0061419 positive regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061419)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.2 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.1 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.2 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.3 GO:0055070 copper ion homeostasis(GO:0055070)
0.0 0.1 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.0 0.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.2 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.3 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.1 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.2 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.3 GO:0009642 response to light intensity(GO:0009642)
0.0 0.3 GO:0055026 negative regulation of cardiac muscle tissue development(GO:0055026)
0.0 1.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.0 0.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.0 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.4 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 1.1 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.2 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0097196 Shu complex(GO:0097196)
0.0 0.2 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.6 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.4 GO:0030914 STAGA complex(GO:0030914)
0.0 0.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.5 GO:0045095 keratin filament(GO:0045095)
0.0 0.6 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.0 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.1 GO:0035363 histone locus body(GO:0035363)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.0 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.7 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.2 0.7 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1 0.4 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.1 1.7 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.6 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 0.4 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.4 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.5 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.3 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.2 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.1 GO:0004773 steryl-sulfatase activity(GO:0004773)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.2 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.7 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 1.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.7 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.3 GO:0070492 phosphatidylinositol-5-phosphate binding(GO:0010314) oligosaccharide binding(GO:0070492)
0.0 0.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.0 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.8 PID E2F PATHWAY E2F transcription factor network
0.0 0.7 PID MYC PATHWAY C-MYC pathway
0.0 0.8 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.6 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.8 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.5 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.6 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.7 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.7 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.5 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.6 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events