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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for HOXB7

Z-value: 0.39

Motif logo

Transcription factors associated with HOXB7

Gene Symbol Gene ID Gene Info
ENSG00000260027.5 HOXB7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB7hg38_v1_chr17_-_48610971_48611023-0.527.6e-03Click!

Activity profile of HOXB7 motif

Sorted Z-values of HOXB7 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB7

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr21_+_42199686 1.27 ENST00000398457.6
ATP binding cassette subfamily G member 1
chr17_-_1229706 1.17 ENST00000574139.7
ABR activator of RhoGEF and GTPase
chr15_+_67125707 1.12 ENST00000540846.6
SMAD family member 3
chr11_-_102798148 0.97 ENST00000315274.7
matrix metallopeptidase 1
chrX_+_9463272 0.74 ENST00000407597.7
ENST00000380961.5
ENST00000424279.6
transducin beta like 1 X-linked
chr5_+_132073782 0.73 ENST00000296871.4
colony stimulating factor 2
chr1_+_218345326 0.64 ENST00000366930.9
transforming growth factor beta 2
chr11_-_57427474 0.56 ENST00000533235.5
ENST00000526621.5
ENST00000352187.5
solute carrier family 43 member 3
chr10_+_13099440 0.53 ENST00000263036.9
optineurin
chr3_+_173398438 0.48 ENST00000457714.5
neuroligin 1
chr6_+_113857333 0.46 ENST00000612661.2
myristoylated alanine rich protein kinase C substrate
chr7_-_45111673 0.44 ENST00000461363.1
ENST00000258770.8
ENST00000495078.1
ENST00000494076.5
ENST00000478532.5
ENST00000361278.7
transforming growth factor beta regulator 4
chr10_+_13099585 0.44 ENST00000378764.6
optineurin
chr3_-_71064964 0.43 ENST00000650387.1
forkhead box P1
chr3_-_71064915 0.43 ENST00000614176.5
ENST00000485326.7
forkhead box P1
chr21_+_25639272 0.43 ENST00000400532.5
ENST00000312957.9
junctional adhesion molecule 2
chr2_+_102418642 0.42 ENST00000264260.6
interleukin 18 receptor accessory protein
chr14_+_51489112 0.42 ENST00000356218.8
FERM domain containing 6
chr10_+_13100075 0.41 ENST00000378747.8
ENST00000378757.6
ENST00000378752.7
ENST00000378748.7
optineurin
chr4_-_122621011 0.41 ENST00000611104.2
ENST00000648588.1
interleukin 21
chr21_+_25639251 0.41 ENST00000480456.6
junctional adhesion molecule 2
chr2_+_89947508 0.40 ENST00000491977.1
immunoglobulin kappa variable 2D-29
chr20_-_1329131 0.39 ENST00000360779.4
syndecan binding protein 2
chr10_+_24466487 0.38 ENST00000396446.5
ENST00000396445.5
ENST00000376451.4
KIAA1217
chr6_+_29100609 0.37 ENST00000377171.3
olfactory receptor family 2 subfamily J member 1
chr1_-_100895132 0.37 ENST00000535414.5
exostosin like glycosyltransferase 2
chr18_+_63887698 0.36 ENST00000457692.5
ENST00000299502.9
ENST00000413956.5
serpin family B member 2
chr17_-_43661915 0.34 ENST00000318579.9
ENST00000393661.2
mesenchyme homeobox 1
chr3_-_190122317 0.34 ENST00000427335.6
prolyl 3-hydroxylase 2
chr12_-_39340963 0.33 ENST00000552961.5
kinesin family member 21A
chr5_+_126423363 0.33 ENST00000285689.8
GRAM domain containing 2B
chr4_-_69214743 0.33 ENST00000446444.2
UDP glucuronosyltransferase family 2 member B11
chr2_-_96505345 0.33 ENST00000310865.7
ENST00000451794.6
neuralized E3 ubiquitin protein ligase 3
chr10_+_116545907 0.32 ENST00000369221.2
pancreatic lipase
chr2_-_24328113 0.32 ENST00000622089.4
intersectin 2
chr2_+_27496830 0.31 ENST00000264717.7
glucokinase regulator
chr9_-_83267230 0.31 ENST00000328788.5
FERM domain containing 3
chr4_-_48012934 0.31 ENST00000420489.7
ENST00000504722.6
cyclic nucleotide gated channel subunit alpha 1
chr7_-_80919017 0.30 ENST00000265361.8
semaphorin 3C
chr2_+_167187283 0.30 ENST00000409605.1
ENST00000409273.6
xin actin binding repeat containing 2
chr2_+_167187364 0.29 ENST00000672671.1
xin actin binding repeat containing 2
chr12_-_91179355 0.29 ENST00000550563.5
ENST00000546370.5
decorin
chr5_-_58999885 0.29 ENST00000317118.12
phosphodiesterase 4D
chr3_-_142448060 0.29 ENST00000264951.8
5'-3' exoribonuclease 1
chr11_-_5324297 0.28 ENST00000624187.1
olfactory receptor family 51 subfamily B member 2
chr5_+_126423122 0.28 ENST00000515200.5
GRAM domain containing 2B
chr11_+_96389985 0.27 ENST00000332349.5
JRK like
chr13_-_103066411 0.27 ENST00000245312.5
solute carrier family 10 member 2
chr19_-_14835162 0.27 ENST00000322301.5
olfactory receptor family 7 subfamily A member 5
chr11_-_123654581 0.27 ENST00000392770.6
ENST00000530277.5
ENST00000299333.8
sodium voltage-gated channel beta subunit 3
chr5_+_126423176 0.27 ENST00000542322.5
ENST00000544396.5
GRAM domain containing 2B
chr12_+_21372899 0.27 ENST00000240652.8
ENST00000542023.1
ENST00000537593.1
islet amyloid polypeptide
chr11_-_123654939 0.26 ENST00000657191.1
sodium voltage-gated channel beta subunit 3
chr22_-_30246739 0.26 ENST00000403987.3
ENST00000249075.4
LIF interleukin 6 family cytokine
chr15_+_64387828 0.26 ENST00000261884.8
thyroid hormone receptor interactor 4
chr14_+_34993240 0.26 ENST00000677647.1
signal recognition particle 54
chr18_+_58196736 0.26 ENST00000675221.1
NEDD4 like E3 ubiquitin protein ligase
chr3_-_142448028 0.26 ENST00000392981.7
5'-3' exoribonuclease 1
chr2_-_10447771 0.26 ENST00000405333.5
ENST00000443218.1
ornithine decarboxylase 1
chr3_-_109118131 0.26 ENST00000232603.10
MORC family CW-type zinc finger 1
chr8_-_10655137 0.26 ENST00000382483.4
RP1 like 1
chr5_+_126360113 0.25 ENST00000513040.5
GRAM domain containing 2B
chr11_-_57324907 0.25 ENST00000358252.8
tankyrase 1 binding protein 1
chr17_+_21126947 0.25 ENST00000579303.5
dehydrogenase/reductase 7B
chr4_-_68670648 0.25 ENST00000338206.6
UDP glucuronosyltransferase family 2 member B15
chr6_+_31586124 0.24 ENST00000418507.6
ENST00000376096.5
ENST00000376099.5
ENST00000376110.7
leukocyte specific transcript 1
chr2_-_160493799 0.24 ENST00000348849.8
RNA binding motif single stranded interacting protein 1
chr6_+_45422485 0.24 ENST00000359524.7
RUNX family transcription factor 2
chr6_+_31586269 0.24 ENST00000438075.7
leukocyte specific transcript 1
chr1_-_160954801 0.23 ENST00000368029.4
intelectin 2
chr5_-_77492199 0.23 ENST00000515253.5
ENST00000507654.5
ENST00000514559.5
ENST00000511791.1
WD repeat domain 41
chr7_+_20330893 0.23 ENST00000222573.5
integrin subunit beta 8
chr14_-_73950393 0.22 ENST00000651776.1
FAM161 centrosomal protein B
chr6_+_45422564 0.22 ENST00000625924.1
RUNX family transcription factor 2
chr6_-_65707214 0.22 ENST00000370621.7
ENST00000393380.6
ENST00000503581.6
eyes shut homolog
chr6_-_152563271 0.21 ENST00000535896.7
ENST00000672122.1
spectrin repeat containing nuclear envelope protein 1
chr11_-_55936400 0.21 ENST00000301532.3
olfactory receptor family 5 subfamily I member 1
chrX_+_1268786 0.21 ENST00000501036.7
ENST00000417535.7
colony stimulating factor 2 receptor subunit alpha
chr12_-_86256267 0.21 ENST00000620241.4
MGAT4 family member C
chrX_+_1268807 0.20 ENST00000381524.8
ENST00000381529.9
ENST00000412290.6
colony stimulating factor 2 receptor subunit alpha
chr2_+_161136901 0.20 ENST00000259075.6
ENST00000432002.5
TRAF family member associated NFKB activator
chr11_-_102625332 0.20 ENST00000260228.3
matrix metallopeptidase 20
chr15_-_74082550 0.20 ENST00000290438.3
golgin A6 family member A
chr12_+_64497968 0.20 ENST00000676593.1
ENST00000677093.1
TANK binding kinase 1
novel transcript
chr1_+_75134382 0.19 ENST00000356261.4
LIM homeobox 8
chr10_+_116324440 0.19 ENST00000333254.4
coiled-coil domain containing 172
chr17_+_43211835 0.19 ENST00000588693.5
ENST00000588659.5
ENST00000541594.5
ENST00000536052.5
ENST00000612339.4
transmembrane protein 106A
chr20_+_41340780 0.18 ENST00000373257.8
lipin 3
chr19_-_49451793 0.18 ENST00000262265.10
PIH1 domain containing 1
chr4_+_168092530 0.18 ENST00000359299.8
annexin A10
chr3_+_98353854 0.17 ENST00000354924.2
olfactory receptor family 5 subfamily K member 4
chrX_+_136305988 0.17 ENST00000394141.1
adhesion G protein-coupled receptor G4
chr3_+_68006224 0.17 ENST00000496687.1
TAFA chemokine like family member 1
chr2_+_89884740 0.17 ENST00000509129.1
immunoglobulin kappa variable 1D-37 (non-functional)
chr3_-_58627596 0.17 ENST00000474531.5
ENST00000465970.1
family with sequence similarity 107 member A
chr5_-_139383284 0.17 ENST00000353963.7
ENST00000348729.8
solute carrier family 23 member 1
chrX_+_56563569 0.17 ENST00000338222.7
ubiquilin 2
chr8_+_10095704 0.17 ENST00000382490.9
methionine sulfoxide reductase A
chr12_-_91111460 0.16 ENST00000266718.5
lumican
chr15_-_85794902 0.16 ENST00000337975.6
kelch like family member 25
chr3_+_181711915 0.16 ENST00000325404.3
SRY-box transcription factor 2
chr16_-_69754913 0.16 ENST00000268802.10
NIN1 (RPN12) binding protein 1 homolog
chr7_+_120273129 0.16 ENST00000331113.9
potassium voltage-gated channel subfamily D member 2
chr3_+_141386862 0.16 ENST00000513258.5
zinc finger and BTB domain containing 38
chr17_-_41140487 0.16 ENST00000345847.4
keratin associated protein 4-6
chr4_+_99574812 0.16 ENST00000422897.6
ENST00000265517.10
microsomal triglyceride transfer protein
chr3_-_112845950 0.16 ENST00000398214.5
CD200 receptor 1 like
chr17_+_8288637 0.15 ENST00000407006.8
ENST00000226105.11
ENST00000580434.5
ENST00000439238.3
RAN guanine nucleotide release factor
chr3_+_156291834 0.15 ENST00000389634.5
potassium voltage-gated channel subfamily A member regulatory beta subunit 1
chr1_+_103750406 0.15 ENST00000370079.3
amylase alpha 1C
chr1_-_152115443 0.15 ENST00000614923.1
trichohyalin
chr8_-_113436883 0.15 ENST00000455883.2
ENST00000297405.10
CUB and Sushi multiple domains 3
chr8_+_10095551 0.15 ENST00000522907.5
ENST00000528246.5
methionine sulfoxide reductase A
chrX_+_1268828 0.15 ENST00000432318.8
ENST00000381509.8
ENST00000494969.7
ENST00000355805.7
ENST00000355432.8
colony stimulating factor 2 receptor subunit alpha
chr11_-_104968533 0.15 ENST00000444739.7
caspase 4
chr12_+_53954870 0.15 ENST00000243103.4
homeobox C12
chr17_-_66229380 0.15 ENST00000205948.11
apolipoprotein H
chr12_+_21526287 0.15 ENST00000256969.7
spexin hormone
chr9_+_107306459 0.14 ENST00000457811.1
RAD23 homolog B, nucleotide excision repair protein
chr9_-_125484490 0.14 ENST00000444226.1
MAPK associated protein 1
chr1_-_165445220 0.14 ENST00000619224.1
retinoid X receptor gamma
chr16_-_84187026 0.14 ENST00000561955.1
ENST00000564454.1
ENST00000341690.10
ENST00000566732.6
ENST00000570117.5
ENST00000564345.5
ENST00000541676.5
TATA-box binding protein associated factor, RNA polymerase I subunit C
chr1_-_165445088 0.14 ENST00000359842.10
retinoid X receptor gamma
chr7_-_27102669 0.14 ENST00000222718.7
homeobox A2
chr12_+_18242955 0.14 ENST00000676171.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr16_-_84186998 0.14 ENST00000567759.5
TATA-box binding protein associated factor, RNA polymerase I subunit C
chr7_-_106285898 0.14 ENST00000424768.2
ENST00000681255.1
nicotinamide phosphoribosyltransferase
chr1_+_168179030 0.13 ENST00000367830.3
TOR signaling pathway regulator
chr8_+_103880412 0.13 ENST00000436393.6
regulating synaptic membrane exocytosis 2
chr3_-_46566276 0.13 ENST00000395905.8
leucine rich repeat containing 2
chr15_+_49423233 0.13 ENST00000560270.1
ENST00000267843.9
ENST00000560979.1
fibroblast growth factor 7
chr4_-_117085541 0.13 ENST00000310754.5
translocation associated membrane protein 1 like 1
chrX_+_100584928 0.13 ENST00000373031.5
tenomodulin
chr3_-_122993232 0.13 ENST00000650207.1
ENST00000616742.4
ENST00000393583.6
semaphorin 5B
chr18_+_57352541 0.13 ENST00000324000.4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr7_+_141995872 0.13 ENST00000497673.5
ENST00000620571.1
ENST00000475668.6
maltase-glucoamylase
chr18_+_31591869 0.13 ENST00000237014.8
transthyretin
chr3_+_191329020 0.13 ENST00000392456.4
coiled-coil domain containing 50
chr10_-_60572599 0.13 ENST00000503366.5
ankyrin 3
chr19_-_32869741 0.12 ENST00000590341.5
ENST00000587772.1
ENST00000023064.9
solute carrier family 7 member 9
chr15_+_58138368 0.12 ENST00000219919.9
ENST00000536493.1
aquaporin 9
chr1_-_241357171 0.12 ENST00000440928.6
regulator of G protein signaling 7
chr17_+_47651061 0.12 ENST00000540627.5
karyopherin subunit beta 1
chr11_-_96389936 0.12 ENST00000680763.1
ENST00000679856.1
ENST00000643839.1
ENST00000645500.1
ENST00000530106.2
coiled-coil domain containing 82
chr5_-_179620933 0.12 ENST00000521173.5
heterogeneous nuclear ribonucleoprotein H1
chr1_-_241357225 0.12 ENST00000366565.5
regulator of G protein signaling 7
chr9_-_71121596 0.12 ENST00000377110.9
ENST00000377111.8
ENST00000677713.2
transient receptor potential cation channel subfamily M member 3
chr12_-_66803980 0.12 ENST00000539540.5
ENST00000540433.5
ENST00000541947.1
ENST00000538373.1
glutamate receptor interacting protein 1
chrX_-_1212634 0.12 ENST00000381567.8
ENST00000381566.6
ENST00000400841.8
cytokine receptor like factor 2
chr11_-_96389857 0.11 ENST00000680532.1
ENST00000681014.1
ENST00000679708.1
ENST00000645439.1
ENST00000645366.1
ENST00000680728.1
ENST00000680859.1
ENST00000679788.1
ENST00000681164.1
ENST00000646818.2
ENST00000680171.1
ENST00000679696.1
ENST00000681200.1
ENST00000679960.1
ENST00000647080.1
ENST00000646050.1
ENST00000681451.1
ENST00000644686.1
ENST00000680052.1
ENST00000679616.1
ENST00000530203.2
coiled-coil domain containing 82
chr16_-_28623560 0.11 ENST00000350842.8
sulfotransferase family 1A member 1
chr1_-_103696209 0.11 ENST00000330330.10
amylase alpha 1B
chr3_+_189631373 0.11 ENST00000264731.8
ENST00000418709.6
ENST00000320472.9
ENST00000392460.7
ENST00000440651.6
tumor protein p63
chr6_-_89315291 0.11 ENST00000402938.4
gamma-aminobutyric acid type A receptor subunit rho2
chr2_-_142131004 0.11 ENST00000434794.1
ENST00000389484.8
LDL receptor related protein 1B
chr8_+_12945667 0.11 ENST00000524591.7
tRNA methyltransferase 9B (putative)
chrX_+_96684712 0.11 ENST00000373049.8
diaphanous related formin 2
chr6_-_116545658 0.11 ENST00000368602.4
trafficking protein particle complex 3 like
chr11_-_107858777 0.11 ENST00000525815.6
solute carrier family 35 member F2
chr12_+_51590873 0.11 ENST00000667214.1
ENST00000662684.1
ENST00000638820.1
sodium voltage-gated channel alpha subunit 8
chr12_+_112791933 0.11 ENST00000551052.5
ENST00000415485.7
rabphilin 3A
chr11_+_114400030 0.11 ENST00000540163.5
RNA binding motif protein 7
chr4_+_112647059 0.11 ENST00000511529.1
La ribonucleoprotein 7, transcriptional regulator
chr1_+_146949314 0.11 ENST00000617844.4
ENST00000611443.4
NBPF member 12
chr9_-_120877026 0.11 ENST00000436309.5
PHD finger protein 19
chr3_+_160225409 0.11 ENST00000326474.5
chromosome 3 open reading frame 80
chr1_+_103617427 0.11 ENST00000423678.2
ENST00000414303.7
amylase alpha 2A
chr12_+_112791738 0.11 ENST00000389385.9
rabphilin 3A
chr11_+_125746272 0.11 ENST00000305738.10
ENST00000437148.2
prostate and testis expressed 1
chr8_-_108787563 0.11 ENST00000297459.4
transmembrane protein 74
chr10_+_102776237 0.10 ENST00000369889.5
WW domain binding protein 1 like
chr2_+_168802610 0.10 ENST00000397206.6
ENST00000317647.12
ENST00000397209.6
nitric oxide synthase trafficking
chr8_-_66178455 0.10 ENST00000276571.5
corticotropin releasing hormone
chr11_-_13495984 0.10 ENST00000282091.6
parathyroid hormone
chr4_-_154590735 0.10 ENST00000403106.8
ENST00000622532.1
ENST00000651975.1
fibrinogen alpha chain
chr15_+_85380672 0.10 ENST00000361243.6
ENST00000560256.1
A-kinase anchoring protein 13
chr15_+_85380565 0.10 ENST00000559362.5
ENST00000394518.7
A-kinase anchoring protein 13
chr11_+_67452392 0.10 ENST00000438189.6
calcium binding protein 4
chr9_-_120876356 0.10 ENST00000456291.1
PHD finger protein 19
chr19_-_54242751 0.10 ENST00000245621.6
ENST00000396365.6
leukocyte immunoglobulin like receptor A6
chr17_-_5035418 0.10 ENST00000254853.10
ENST00000424747.1
solute carrier family 52 member 1
chr17_+_1771688 0.10 ENST00000572048.1
ENST00000573763.1
serpin family F member 1
chr17_-_44066595 0.10 ENST00000585388.2
ENST00000293406.8
LSM12 homolog
chr12_+_95858928 0.10 ENST00000266735.9
ENST00000553192.5
ENST00000552085.1
small nuclear ribonucleoprotein polypeptide F
chr4_-_145180496 0.10 ENST00000447906.8
OTU deubiquitinase 4
chr7_+_30145789 0.10 ENST00000324489.5
maturin, neural progenitor differentiation regulator homolog
chr11_+_31816266 0.10 ENST00000644607.1
ENST00000646221.1
ENST00000643671.1
ENST00000643931.1
ENST00000642614.1
ENST00000642818.1
ENST00000645848.1
ENST00000506388.2
ENST00000645824.1
ENST00000532942.5
PAX6 upstream antisense RNA
novel protein
chr16_-_66730216 0.10 ENST00000569320.5
dynein cytoplasmic 1 light intermediate chain 2
chr12_+_56007484 0.10 ENST00000262032.9
IKAROS family zinc finger 4
chr9_+_72114595 0.09 ENST00000545168.5
guanine deaminase
chr1_+_107141022 0.09 ENST00000370067.5
ENST00000370068.6
netrin G1
chrX_+_30243715 0.09 ENST00000378981.8
ENST00000397550.6
MAGE family member B1
chr2_-_108989206 0.09 ENST00000258443.7
ENST00000409271.5
ENST00000376651.1
ectodysplasin A receptor
chr7_-_124765753 0.09 ENST00000303921.3
G protein-coupled receptor 37
chr5_+_163460650 0.09 ENST00000358715.3
hyaluronan mediated motility receptor
chr12_+_9827472 0.09 ENST00000617793.4
ENST00000617889.5
ENST00000354855.7
ENST00000279545.7
killer cell lectin like receptor F1
chr2_+_27032938 0.09 ENST00000238788.14
ENST00000404032.7
transmembrane protein 214
chr14_+_64704380 0.09 ENST00000247226.13
ENST00000394691.7
pleckstrin homology and RhoGEF domain containing G3
chrX_-_111412162 0.09 ENST00000637570.1
ENST00000356220.8
ENST00000636035.2
ENST00000637453.1
ENST00000635795.1
doublecortin
chr2_-_86105839 0.09 ENST00000263857.11
RNA polymerase I subunit A

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0009720 detection of hormone stimulus(GO:0009720)
0.3 1.2 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.2 0.6 GO:1905006 negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006)
0.2 1.4 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.2 1.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.2 0.2 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.1 0.7 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 0.6 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 0.5 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.1 0.4 GO:0061056 sclerotome development(GO:0061056)
0.1 0.4 GO:0003383 apical constriction(GO:0003383)
0.1 0.3 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 0.2 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.5 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.3 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.1 0.4 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.2 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.1 0.2 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.3 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 0.5 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.9 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.2 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.0 0.1 GO:0021593 rhombomere morphogenesis(GO:0021593) rhombomere 3 morphogenesis(GO:0021658)
0.0 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.3 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.2 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186) negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.0 0.3 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.1 GO:0042322 negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322) negative regulation of glucagon secretion(GO:0070093) cellular response to cocaine(GO:0071314)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.0 0.1 GO:0006147 guanine catabolic process(GO:0006147)
0.0 0.1 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0015855 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.3 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.1 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 0.1 GO:1904306 regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.1 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.4 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.5 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.0 0.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.1 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.0 1.0 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.2 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0050758 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) cellular response to folic acid(GO:0071231)
0.0 0.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:1903538 meiotic spindle elongation(GO:0051232) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.0 0.5 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.2 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.2 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.1 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.0 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.2 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.1 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.1 GO:0007538 primary sex determination(GO:0007538)
0.0 0.0 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.1 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.0 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.2 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.3 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) cellular response to cobalt ion(GO:0071279)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.1 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.4 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.2 GO:0042448 progesterone metabolic process(GO:0042448)
0.0 0.4 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.4 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.1 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 0.2 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 1.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.2 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.3 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 1.7 GO:0005776 autophagosome(GO:0005776)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 1.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.0 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.0 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.2 1.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.4 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.1 0.6 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.6 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.3 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.1 0.3 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.3 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.3 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.4 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.2 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.3 GO:0016160 amylase activity(GO:0016160)
0.1 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 1.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0008892 guanine deaminase activity(GO:0008892)
0.0 0.1 GO:0036505 prosaposin receptor activity(GO:0036505)
0.0 0.1 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.0 0.1 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.0 0.3 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 0.1 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 0.1 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.3 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.0 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.9 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 1.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination