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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for HOXB8

Z-value: 0.87

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Transcription factors associated with HOXB8

Gene Symbol Gene ID Gene Info
ENSG00000120068.7 HOXB8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB8hg38_v1_chr17_-_48613468_48613522-0.154.8e-01Click!

Activity profile of HOXB8 motif

Sorted Z-values of HOXB8 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB8

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr4_-_122621011 1.69 ENST00000611104.2
ENST00000648588.1
interleukin 21
chr5_+_157269317 1.35 ENST00000618329.4
cytoplasmic FMR1 interacting protein 2
chr1_+_86547070 1.16 ENST00000370563.3
chloride channel accessory 4
chr9_-_83267230 1.14 ENST00000328788.5
FERM domain containing 3
chr3_+_148827800 1.10 ENST00000282957.9
ENST00000468341.1
carboxypeptidase B1
chr15_+_76336755 1.04 ENST00000290759.9
ISL LIM homeobox 2
chr19_-_14835162 0.96 ENST00000322301.5
olfactory receptor family 7 subfamily A member 5
chr10_-_88952763 0.95 ENST00000224784.10
actin alpha 2, smooth muscle
chr7_-_116030735 0.89 ENST00000393485.5
transcription factor EC
chr20_-_56497608 0.86 ENST00000617620.1
glucosaminyl (N-acetyl) transferase family member 7
chr2_-_201697993 0.85 ENST00000428900.6
membrane palmitoylated protein 4
chr3_+_151814102 0.82 ENST00000232892.12
arylacetamide deacetylase
chr11_-_5324297 0.79 ENST00000624187.1
olfactory receptor family 51 subfamily B member 2
chr11_+_5389377 0.79 ENST00000328611.5
olfactory receptor family 51 subfamily M member 1
chr10_+_68106109 0.79 ENST00000540630.5
ENST00000354393.6
myopalladin
chr7_-_116030750 0.76 ENST00000265440.12
ENST00000320239.11
transcription factor EC
chr2_-_201698040 0.76 ENST00000396886.7
ENST00000409143.5
membrane palmitoylated protein 4
chr3_-_191282383 0.71 ENST00000427544.6
urotensin 2B
chr8_-_134510182 0.69 ENST00000521673.5
zinc finger and AT-hook domain containing
chr22_+_22704265 0.68 ENST00000390307.2
immunoglobulin lambda variable 3-22
chr4_-_69214743 0.67 ENST00000446444.2
UDP glucuronosyltransferase family 2 member B11
chr3_+_155083889 0.66 ENST00000680282.1
membrane metalloendopeptidase
chr6_-_52840843 0.66 ENST00000370989.6
glutathione S-transferase alpha 5
chr6_-_132659178 0.66 ENST00000275216.3
trace amine associated receptor 1
chr1_+_78620432 0.62 ENST00000370751.10
ENST00000459784.6
ENST00000680110.1
ENST00000680295.1
interferon induced protein 44 like
chr6_-_118710065 0.60 ENST00000392500.7
ENST00000368488.9
ENST00000434604.5
centrosomal protein 85 like
chr5_-_135954962 0.58 ENST00000522943.5
ENST00000514447.2
ENST00000274507.6
leukocyte cell derived chemotaxin 2
chr12_-_16600703 0.57 ENST00000616247.4
LIM domain only 3
chr11_-_102625332 0.57 ENST00000260228.3
matrix metallopeptidase 20
chr2_+_89884740 0.55 ENST00000509129.1
immunoglobulin kappa variable 1D-37 (non-functional)
chr4_+_69280472 0.55 ENST00000335568.10
ENST00000511240.1
UDP glucuronosyltransferase family 2 member B28
chr21_-_10649835 0.55 ENST00000622028.1
immunoglobulin heavy variable 1/OR21-1 (non-functional)
chr12_-_7444139 0.55 ENST00000416109.2
ENST00000313599.8
CD163 molecule like 1
chr16_-_28623560 0.55 ENST00000350842.8
sulfotransferase family 1A member 1
chr1_-_247758680 0.54 ENST00000408896.4
olfactory receptor family 1 subfamily C member 1
chr3_-_15440560 0.53 ENST00000595627.5
ENST00000597949.1
ENST00000494875.3
ENST00000595975.1
ENST00000598878.1
EAF1 antisense RNA 1
methyltransferase like 6
chr5_-_59216826 0.53 ENST00000638939.1
phosphodiesterase 4D
chr19_-_10587219 0.53 ENST00000591240.5
ENST00000589684.5
ENST00000591676.1
ENST00000250244.11
ENST00000590923.5
adaptor related protein complex 1 subunit mu 2
chr1_+_214603173 0.52 ENST00000366955.8
centromere protein F
chr17_-_41140487 0.51 ENST00000345847.4
keratin associated protein 4-6
chr9_+_122370523 0.51 ENST00000643810.1
ENST00000540753.6
prostaglandin-endoperoxide synthase 1
chr7_-_138679045 0.50 ENST00000419765.4
SVOP like
chr15_+_67125707 0.49 ENST00000540846.6
SMAD family member 3
chr3_+_155083523 0.48 ENST00000680057.1
membrane metalloendopeptidase
chr4_-_76023489 0.47 ENST00000306602.3
C-X-C motif chemokine ligand 10
chr10_+_68109433 0.47 ENST00000613327.4
ENST00000358913.10
ENST00000373675.3
myopalladin
chr3_-_112845950 0.47 ENST00000398214.5
CD200 receptor 1 like
chr8_-_133060347 0.46 ENST00000427060.6
Src like adaptor
chr10_+_13100075 0.45 ENST00000378747.8
ENST00000378757.6
ENST00000378752.7
ENST00000378748.7
optineurin
chr1_+_24319342 0.45 ENST00000361548.9
grainyhead like transcription factor 3
chr4_-_176195563 0.44 ENST00000280191.7
spermatogenesis associated 4
chr17_-_1229706 0.44 ENST00000574139.7
ABR activator of RhoGEF and GTPase
chr11_-_7796942 0.44 ENST00000329434.3
olfactory receptor family 5 subfamily P member 2
chr12_-_49897056 0.43 ENST00000552863.5
Fas apoptotic inhibitory molecule 2
chr10_+_13099440 0.43 ENST00000263036.9
optineurin
chr4_+_122732652 0.42 ENST00000542236.5
ENST00000314218.8
Bardet-Biedl syndrome 12
chr5_+_129748091 0.41 ENST00000564719.2
membrane integral NOTCH2 associated receptor 2
chr5_-_58999885 0.41 ENST00000317118.12
phosphodiesterase 4D
chr11_-_114595777 0.41 ENST00000375478.4
neurexophilin and PC-esterase domain family member 4
chr1_-_111563956 0.40 ENST00000369717.8
transmembrane and immunoglobulin domain containing 3
chr3_-_12545499 0.40 ENST00000564146.4
MKRN2 opposite strand
chr1_+_244352627 0.40 ENST00000366537.5
ENST00000308105.5
chromosome 1 open reading frame 100
chr4_+_73481737 0.39 ENST00000226355.5
afamin
chr11_-_102874974 0.39 ENST00000571244.3
matrix metallopeptidase 12
chr1_-_27914513 0.39 ENST00000313433.11
ENST00000373912.8
ENST00000444045.1
replication protein A2
chr3_+_98353854 0.38 ENST00000354924.2
olfactory receptor family 5 subfamily K member 4
chr12_+_112978386 0.38 ENST00000342315.8
2'-5'-oligoadenylate synthetase 2
chr14_-_67412112 0.38 ENST00000216446.9
pleckstrin 2
chr10_+_13099585 0.38 ENST00000378764.6
optineurin
chr3_+_148791058 0.38 ENST00000491148.5
carboxypeptidase B1
chr3_-_122993232 0.38 ENST00000650207.1
ENST00000616742.4
ENST00000393583.6
semaphorin 5B
chr12_+_21526287 0.37 ENST00000256969.7
spexin hormone
chr7_+_70596078 0.37 ENST00000644506.1
activator of transcription and developmental regulator AUTS2
chr6_-_132763424 0.37 ENST00000532012.1
ENST00000525270.5
ENST00000530536.5
ENST00000524919.5
vanin 2
chr2_-_99255107 0.37 ENST00000333017.6
ENST00000626374.2
ENST00000409679.5
ENST00000423306.1
lysozyme g2
chr7_-_13986439 0.37 ENST00000443608.5
ENST00000438956.5
ETS variant transcription factor 1
chr11_+_96389985 0.36 ENST00000332349.5
JRK like
chr7_-_80919017 0.36 ENST00000265361.8
semaphorin 3C
chr16_-_67416420 0.36 ENST00000348579.6
ENST00000565726.3
zinc finger DHHC-type containing 1
chr22_-_30246739 0.36 ENST00000403987.3
ENST00000249075.4
LIF interleukin 6 family cytokine
chr4_+_87832917 0.35 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
matrix extracellular phosphoglycoprotein
chr5_+_122129533 0.35 ENST00000296600.5
ENST00000504912.1
ENST00000505843.1
zinc finger protein 474
chr11_-_124315099 0.35 ENST00000641897.1
olfactory receptor family 8 subfamily D member 1
chr8_-_100106034 0.35 ENST00000360863.11
ENST00000617334.1
regulator of G protein signaling 22
chr4_+_168092530 0.35 ENST00000359299.8
annexin A10
chr9_+_72577369 0.35 ENST00000651183.1
transmembrane channel like 1
chr15_-_79971164 0.35 ENST00000335661.6
ENST00000267953.4
ENST00000677151.1
BCL2 related protein A1
chr17_+_41249687 0.35 ENST00000334109.3
keratin associated protein 9-4
chr3_-_108058361 0.34 ENST00000398258.7
CD47 molecule
chr20_+_33217325 0.34 ENST00000375452.3
ENST00000375454.8
BPI fold containing family A member 3
chr7_-_45111673 0.34 ENST00000461363.1
ENST00000258770.8
ENST00000495078.1
ENST00000494076.5
ENST00000478532.5
ENST00000361278.7
transforming growth factor beta regulator 4
chr17_-_41009124 0.34 ENST00000391588.3
keratin associated protein 3-1
chr18_+_63887698 0.34 ENST00000457692.5
ENST00000299502.9
ENST00000413956.5
serpin family B member 2
chr2_+_167135901 0.33 ENST00000628543.2
xin actin binding repeat containing 2
chr11_-_60243103 0.33 ENST00000651255.1
membrane spanning 4-domains A4E
chr10_+_96129707 0.32 ENST00000316045.9
zinc finger protein 518A
chr5_-_41213505 0.32 ENST00000337836.10
ENST00000433294.1
complement C6
chr1_-_154627945 0.32 ENST00000681683.1
ENST00000368471.8
ENST00000649042.1
ENST00000680270.1
ENST00000649022.2
ENST00000681056.1
ENST00000649724.1
adenosine deaminase RNA specific
chr10_+_94683771 0.32 ENST00000339022.6
cytochrome P450 family 2 subfamily C member 18
chr14_+_22508602 0.32 ENST00000390504.1
T cell receptor alpha joining 33
chr10_+_114239245 0.32 ENST00000392982.8
von Willebrand factor A domain containing 2
chr17_-_40937641 0.32 ENST00000209718.8
keratin 23
chr9_+_108862255 0.32 ENST00000333999.5
actin like 7A
chr11_-_18939493 0.31 ENST00000526914.1
MAS related GPR family member X1
chrX_+_134990980 0.31 ENST00000330288.6
small integral membrane protein 10
chr18_+_74534493 0.30 ENST00000358821.8
carnosine dipeptidase 1
chr12_+_9827472 0.30 ENST00000617793.4
ENST00000617889.5
ENST00000354855.7
ENST00000279545.7
killer cell lectin like receptor F1
chr3_+_130081831 0.30 ENST00000425059.1
ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase like 2
chr4_-_71784046 0.30 ENST00000513476.5
ENST00000273951.13
GC vitamin D binding protein
chr19_-_52095704 0.30 ENST00000594440.6
ENST00000426391.6
zinc finger protein 841
chr19_+_54803604 0.30 ENST00000359085.8
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4
chr7_-_105679089 0.30 ENST00000477775.5
ataxin 7 like 1
chr14_+_75605462 0.30 ENST00000539311.5
FLVCR heme transporter 2
chr8_+_36784324 0.30 ENST00000523973.5
ENST00000399881.8
potassium calcium-activated channel subfamily U member 1
chr10_+_92593112 0.29 ENST00000260731.5
kinesin family member 11
chr14_+_73591873 0.29 ENST00000326303.5
acyl-CoA thioesterase 4
chr8_+_103880412 0.29 ENST00000436393.6
regulating synaptic membrane exocytosis 2
chr6_+_26365176 0.29 ENST00000377708.7
butyrophilin subfamily 3 member A2
chr10_+_60778490 0.29 ENST00000448257.6
ENST00000614696.4
cyclin dependent kinase 1
chr3_-_58627596 0.29 ENST00000474531.5
ENST00000465970.1
family with sequence similarity 107 member A
chr6_+_26365215 0.29 ENST00000527422.5
ENST00000356386.6
ENST00000396948.5
butyrophilin subfamily 3 member A2
chr9_-_146140 0.29 ENST00000475990.5
COBW domain containing 1
chr1_+_24319511 0.29 ENST00000356046.6
grainyhead like transcription factor 3
chr18_+_74534594 0.28 ENST00000582365.1
carnosine dipeptidase 1
chr1_-_200620729 0.28 ENST00000367350.5
kinesin family member 14
chr1_-_89198868 0.28 ENST00000355754.7
guanylate binding protein 4
chr7_+_120273129 0.28 ENST00000331113.9
potassium voltage-gated channel subfamily D member 2
chr5_+_162067858 0.27 ENST00000361925.9
gamma-aminobutyric acid type A receptor subunit gamma2
chr10_-_78029487 0.27 ENST00000372371.8
RNA polymerase III subunit A
chr12_-_262828 0.27 ENST00000343164.9
ENST00000436453.1
ENST00000445055.6
ENST00000546319.5
solute carrier family 6 member 13
chr10_-_13099652 0.27 ENST00000378839.1
coiled-coil domain containing 3
chr8_+_18391276 0.27 ENST00000286479.4
ENST00000520116.1
N-acetyltransferase 2
chr4_-_129093454 0.27 ENST00000281142.10
ENST00000511426.5
sodium channel and clathrin linker 1
chr10_+_60778331 0.27 ENST00000519078.6
ENST00000316629.8
ENST00000395284.8
cyclin dependent kinase 1
chr16_-_28623330 0.27 ENST00000677940.1
novel protein
chr8_+_85107172 0.26 ENST00000360375.8
leucine rich repeat and coiled-coil centrosomal protein 1
chr11_-_114595750 0.26 ENST00000424261.6
neurexophilin and PC-esterase domain family member 4
chrX_-_111412162 0.26 ENST00000637570.1
ENST00000356220.8
ENST00000636035.2
ENST00000637453.1
ENST00000635795.1
doublecortin
chr8_-_100105955 0.26 ENST00000523437.5
regulator of G protein signaling 22
chr17_+_42773442 0.26 ENST00000253794.7
ENST00000590339.5
ENST00000589520.1
vacuolar protein sorting 25 homolog
chr8_+_144477975 0.26 ENST00000435887.2
protein phosphatase 1 regulatory subunit 16A
chr2_-_89297785 0.26 ENST00000465170.1
immunoglobulin kappa variable 1-37 (non-functional)
chr1_+_248445512 0.26 ENST00000642130.1
ENST00000641925.2
olfactory receptor family 2 subfamily T member 2
chr4_+_155903688 0.26 ENST00000536354.3
tryptophan 2,3-dioxygenase
chr15_+_84235773 0.26 ENST00000510439.7
ENST00000422563.6
golgin A6 family like 4
chr14_+_51489112 0.26 ENST00000356218.8
FERM domain containing 6
chr20_+_36876119 0.26 ENST00000602922.5
ENST00000217320.8
TBC/LysM-associated domain containing 2
chr19_-_48513161 0.26 ENST00000673139.1
lemur tyrosine kinase 3
chr11_+_57597563 0.26 ENST00000619430.2
ENST00000457869.1
ENST00000340687.10
ENST00000278407.9
ENST00000378323.8
ENST00000378324.6
ENST00000403558.1
serpin family G member 1
chr10_+_55599041 0.25 ENST00000512524.4
MT-RNR2 like 5
chrX_-_152733715 0.25 ENST00000452779.3
ENST00000370287.7
chondrosarcoma associated gene 1
chr1_-_111563934 0.25 ENST00000443498.5
transmembrane and immunoglobulin domain containing 3
chr4_-_70666492 0.25 ENST00000254801.9
ENST00000391614.7
joining chain of multimeric IgA and IgM
chr7_+_97005538 0.25 ENST00000518156.3
distal-less homeobox 6
chr8_-_86743626 0.25 ENST00000320005.6
cyclic nucleotide gated channel subunit beta 3
chr9_+_122371036 0.25 ENST00000619306.5
ENST00000426608.6
ENST00000223423.8
prostaglandin-endoperoxide synthase 1
chr7_-_113086815 0.24 ENST00000424100.2
G protein-coupled receptor 85
chr14_+_19743571 0.24 ENST00000642117.2
olfactory receptor family 4 subfamily Q member 3
chr15_-_82349437 0.24 ENST00000621197.4
ENST00000610657.2
ENST00000619556.4
golgin A6 family like 10
chrX_+_96684712 0.24 ENST00000373049.8
diaphanous related formin 2
chr18_+_24113341 0.23 ENST00000540918.2
tetratricopeptide repeat domain 39C
chr8_-_7018295 0.23 ENST00000327857.7
defensin alpha 3
chr6_+_52420992 0.23 ENST00000636954.1
ENST00000636566.1
ENST00000638075.1
EF-hand domain containing 1
chr12_-_11022620 0.23 ENST00000390673.2
taste 2 receptor member 19
chr15_-_65115185 0.23 ENST00000559089.6
ubiquitin associated protein 1 like
chr14_-_23155302 0.23 ENST00000529705.6
solute carrier family 7 member 8
chr11_+_67452392 0.23 ENST00000438189.6
calcium binding protein 4
chr16_+_8642375 0.23 ENST00000562973.1
methyltransferase like 22
chrX_+_56563569 0.23 ENST00000338222.7
ubiquilin 2
chr1_-_205121964 0.23 ENST00000264515.11
RB binding protein 5, histone lysine methyltransferase complex subunit
chr12_-_51324652 0.23 ENST00000544402.5
bridging integrator 2
chr9_-_92878018 0.23 ENST00000332591.6
ENST00000375495.8
ENST00000395505.6
ENST00000395506.7
zinc finger protein 484
chr10_+_46375645 0.23 ENST00000622769.4
annexin A8 like 1
chr1_+_31413187 0.23 ENST00000373709.8
serine incorporator 2
chr1_+_84408230 0.23 ENST00000370662.3
deoxyribonuclease 2 beta
chr21_-_14546297 0.23 ENST00000400566.6
ENST00000400564.5
SAM domain, SH3 domain and nuclear localization signals 1
chr3_-_149221811 0.23 ENST00000455472.3
ENST00000264613.11
ceruloplasmin
chr10_+_46375619 0.23 ENST00000584982.7
ENST00000613703.4
annexin A8 like 1
chr3_+_142723999 0.23 ENST00000476941.6
ENST00000273482.10
transient receptor potential cation channel subfamily C member 1
chr3_+_108602776 0.22 ENST00000497905.5
ENST00000463306.1
DAZ interacting zinc finger protein 3
chr3_-_179251615 0.22 ENST00000314235.9
ENST00000392685.6
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr12_+_18242955 0.22 ENST00000676171.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr10_+_120851341 0.22 ENST00000263461.11
WD repeat domain 11
chr12_+_8509460 0.22 ENST00000382064.6
C-type lectin domain family 4 member D
chr3_+_2892199 0.22 ENST00000397459.6
contactin 4
chr12_+_80099535 0.22 ENST00000646859.1
ENST00000547103.7
otogelin like
chr11_-_123654939 0.22 ENST00000657191.1
sodium voltage-gated channel beta subunit 3
chr11_-_35360050 0.22 ENST00000644868.1
ENST00000643454.1
ENST00000646080.1
solute carrier family 1 member 2
chrX_-_13817027 0.22 ENST00000493677.5
ENST00000355135.6
ENST00000316715.9
glycoprotein M6B
chr1_-_160579439 0.21 ENST00000368054.8
ENST00000368048.7
ENST00000311224.8
ENST00000368051.3
ENST00000534968.5
CD84 molecule
chr4_+_36281591 0.21 ENST00000639862.2
ENST00000357504.7
death domain containing 1
chr3_+_102099244 0.21 ENST00000491959.5
zona pellucida like domain containing 1
chr2_-_96505345 0.21 ENST00000310865.7
ENST00000451794.6
neuralized E3 ubiquitin protein ligase 3
chr5_-_139383284 0.21 ENST00000353963.7
ENST00000348729.8
solute carrier family 23 member 1
chr12_-_109021015 0.21 ENST00000546618.2
ENST00000610966.5
SV2 related protein
chr20_-_56392131 0.21 ENST00000422322.5
ENST00000371356.6
ENST00000451915.1
ENST00000347343.6
ENST00000395911.5
ENST00000395915.8
ENST00000395907.5
ENST00000441357.5
ENST00000456249.5
ENST00000420474.5
ENST00000395914.5
ENST00000312783.10
ENST00000395913.7
aurora kinase A
chr4_-_159035226 0.21 ENST00000434826.3
chromosome 4 open reading frame 45
chr14_+_22052503 0.21 ENST00000390449.3
T cell receptor alpha variable 21
chr9_+_74497308 0.21 ENST00000376896.8
RAR related orphan receptor B
chrX_-_154371210 0.21 ENST00000369856.8
ENST00000422373.6
ENST00000360319.9
filamin A

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.2 0.9 GO:0090131 mesenchyme migration(GO:0090131)
0.2 1.3 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.2 0.5 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.1 1.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.1 GO:2000506 negative regulation of energy homeostasis(GO:2000506)
0.1 1.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.4 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.1 1.7 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 0.4 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.1 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.1 0.9 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.4 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.5 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.6 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.3 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.1 0.6 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 0.4 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 0.2 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.2 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
0.1 0.2 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 0.6 GO:0014038 regulation of Schwann cell differentiation(GO:0014038) Golgi disassembly(GO:0090166)
0.1 0.2 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 0.1 GO:0042322 negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
0.1 0.1 GO:0035744 T-helper 1 cell cytokine production(GO:0035744)
0.1 0.3 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.8 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.2 GO:0021658 rhombomere morphogenesis(GO:0021593) rhombomere 3 morphogenesis(GO:0021658)
0.1 0.2 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.1 0.2 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.1 0.7 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.1 0.2 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.1 0.2 GO:1904021 negative regulation of clathrin-mediated endocytosis(GO:1900186) negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.1 0.2 GO:0019605 butyrate metabolic process(GO:0019605)
0.1 0.2 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 0.9 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1 1.0 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.2 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.1 0.1 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.1 0.4 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.3 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 0.2 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.1 0.1 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 0.2 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.1 0.2 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.3 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.4 GO:1904306 regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.0 0.2 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.3 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.0 0.4 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.0 0.1 GO:0045359 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.2 GO:0007538 primary sex determination(GO:0007538)
0.0 0.1 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.0 0.5 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.3 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:0009720 detection of hormone stimulus(GO:0009720)
0.0 0.9 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0000023 maltose metabolic process(GO:0000023)
0.0 0.4 GO:2000620 innate vocalization behavior(GO:0098582) positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.2 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.2 GO:0030035 microspike assembly(GO:0030035)
0.0 0.4 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.7 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.7 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.3 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.2 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.1 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.1 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.1 GO:0019087 transformation of host cell by virus(GO:0019087)
0.0 0.1 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.2 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.1 GO:1903410 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.0 0.3 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.4 GO:0018377 protein myristoylation(GO:0018377)
0.0 0.5 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.1 GO:0035698 CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.0 0.3 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.1 GO:0039022 pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
0.0 0.3 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 1.2 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.3 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.1 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.0 0.1 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.3 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.0 0.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.2 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.2 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.4 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.4 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0031296 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.5 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.2 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.2 GO:1903936 cellular response to sodium arsenite(GO:1903936)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:0035880 embryonic nail plate morphogenesis(GO:0035880) establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.1 GO:0071231 cellular response to folic acid(GO:0071231)
0.0 0.1 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.0 0.1 GO:0051792 short-chain fatty acid biosynthetic process(GO:0051790) medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 0.6 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.0 0.1 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.1 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.1 GO:0075732 viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594)
0.0 0.3 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0 0.1 GO:0046103 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.0 0.1 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.0 0.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.2 GO:0051918 negative regulation of smooth muscle cell apoptotic process(GO:0034392) negative regulation of fibrinolysis(GO:0051918)
0.0 0.2 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.0 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.5 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.0 GO:0007008 outer mitochondrial membrane organization(GO:0007008)
0.0 0.1 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.3 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.1 GO:1904252 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.2 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.5 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0006568 tryptophan metabolic process(GO:0006568)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0051410 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.0 0.2 GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0 0.2 GO:0006828 manganese ion transport(GO:0006828)
0.0 2.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.2 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.4 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0051451 myoblast migration(GO:0051451)
0.0 0.8 GO:0051180 vitamin transport(GO:0051180)
0.0 0.2 GO:0006702 androgen biosynthetic process(GO:0006702)
0.0 0.0 GO:0035552 tRNA wobble cytosine modification(GO:0002101) oxidative single-stranded DNA demethylation(GO:0035552)
0.0 0.0 GO:0032831 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.4 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.2 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.0 0.0 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.1 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.2 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.1 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.1 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.2 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.1 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.0 0.4 GO:0048846 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.0 0.2 GO:0008228 opsonization(GO:0008228)
0.0 0.0 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.1 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.3 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.0 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0015747 urate transport(GO:0015747)
0.0 0.3 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.6 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.2 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.6 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 0.3 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.4 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.1 0.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 0.3 GO:0000814 ESCRT II complex(GO:0000814)
0.1 0.3 GO:0071750 dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752) IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
0.1 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 0.2 GO:0000811 GINS complex(GO:0000811)
0.1 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0031523 Myb complex(GO:0031523)
0.0 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.7 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.2 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.5 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.2 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0030849 X chromosome(GO:0000805) autosome(GO:0030849)
0.0 0.3 GO:0043073 germ cell nucleus(GO:0043073)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.0 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 1.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 1.1 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.0 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.1 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.2 0.9 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.4 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.6 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.7 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.3 GO:1902271 D3 vitamins binding(GO:1902271)
0.1 0.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.4 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.5 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.1 0.3 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 0.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.2 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 0.2 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.2 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.1 0.3 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.3 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.1 0.2 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.1 0.2 GO:0005148 prolactin receptor binding(GO:0005148)
0.1 0.2 GO:0097259 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1 0.3 GO:0019862 IgA binding(GO:0019862)
0.0 0.2 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.3 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.2 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.7 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.0 0.2 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.2 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.7 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 1.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.2 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 1.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 0.8 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.8 GO:0035173 histone kinase activity(GO:0035173)
0.0 1.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 1.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.1 GO:0005287 high-affinity basic amino acid transmembrane transporter activity(GO:0005287) high-affinity arginine transmembrane transporter activity(GO:0005289) high-affinity lysine transmembrane transporter activity(GO:0005292)
0.0 0.1 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.6 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.5 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.3 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.3 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.7 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 0.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.7 GO:0005549 odorant binding(GO:0005549)
0.0 0.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.3 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.3 GO:0015266 protein channel activity(GO:0015266)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0016160 amylase activity(GO:0016160)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.2 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.3 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.1 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.0 0.0 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.0 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 1.0 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.1 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 1.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.5 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.0 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 1.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.2 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.5 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.3 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.0 GO:0043734 DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 PID BCR 5PATHWAY BCR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1 1.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.6 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.5 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 2.9 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 1.2 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.7 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.0 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.5 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation