Project

Inflammatory response time course, HUVEC (Wada, 2009)

Navigation
Downloads

Results for HSF1

Z-value: 0.66

Motif logo

Transcription factors associated with HSF1

Gene Symbol Gene ID Gene Info
ENSG00000185122.11 HSF1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HSF1hg38_v1_chr8_+_144291581_144291617-0.164.6e-01Click!

Activity profile of HSF1 motif

Sorted Z-values of HSF1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HSF1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image
Promoter Score Transcript Gene Gene Info
chr7_+_150567347 1.36 ENST00000461940.5
GTPase, IMAP family member 4
chr7_+_150737382 1.23 ENST00000358647.5
GTPase, IMAP family member 5
chr7_+_150567382 1.23 ENST00000255945.4
ENST00000479232.1
GTPase, IMAP family member 4
chr20_-_59007807 1.18 ENST00000680386.1
cathepsin Z
chr8_-_80171106 1.15 ENST00000519303.6
tumor protein D52
chr1_-_160954801 1.10 ENST00000368029.4
intelectin 2
chr4_+_41359599 1.08 ENST00000513024.5
LIM and calponin homology domains 1
chr10_-_114684457 1.05 ENST00000392955.7
actin binding LIM protein 1
chr10_-_114684612 0.96 ENST00000533213.6
ENST00000369252.8
actin binding LIM protein 1
chr2_-_191013955 0.93 ENST00000409465.5
signal transducer and activator of transcription 1
chr2_-_237590660 0.91 ENST00000409576.1
RAB17, member RAS oncogene family
chr16_-_9943182 0.88 ENST00000535259.6
glutamate ionotropic receptor NMDA type subunit 2A
chr4_+_54657918 0.84 ENST00000412167.6
ENST00000288135.6
KIT proto-oncogene, receptor tyrosine kinase
chr17_-_69141878 0.79 ENST00000590645.1
ENST00000284425.7
ATP binding cassette subfamily A member 6
chr9_+_124291935 0.75 ENST00000546191.5
NIMA related kinase 6
chr2_-_191014137 0.72 ENST00000673777.1
ENST00000673942.1
ENST00000424722.6
ENST00000392322.7
ENST00000361099.8
ENST00000392323.6
ENST00000673816.1
ENST00000673847.1
ENST00000673952.1
ENST00000540176.6
ENST00000673841.1
signal transducer and activator of transcription 1
chr2_-_27628975 0.72 ENST00000324364.4
coiled-coil domain containing 121
chrX_-_126552801 0.67 ENST00000371126.3
DDB1 and CUL4 associated factor 12 like 1
chr14_-_22644352 0.65 ENST00000540461.2
olfactory receptor family 6 subfamily J member 1
chr1_+_47023659 0.64 ENST00000371901.4
cytochrome P450 family 4 subfamily X member 1
chr8_-_80171496 0.64 ENST00000379096.9
ENST00000518937.6
tumor protein D52
chr19_+_34926892 0.64 ENST00000303586.11
ENST00000601142.2
ENST00000439785.5
ENST00000601540.5
ENST00000601957.5
zinc finger protein 30
chr14_+_63204436 0.63 ENST00000316754.8
ras homolog family member J
chrX_+_54920796 0.62 ENST00000442098.5
ENST00000430420.5
ENST00000453081.5
ENST00000319167.12
ENST00000622017.4
ENST00000375022.8
ENST00000399736.5
ENST00000440072.5
ENST00000173898.12
ENST00000431115.5
ENST00000440759.5
ENST00000375041.6
trophinin
chr1_+_220879434 0.61 ENST00000366903.8
H2.0 like homeobox
chr10_-_96358989 0.61 ENST00000371172.8
oligodendrocytic myelin paranodal and inner loop protein
chr9_+_117704168 0.61 ENST00000472304.2
ENST00000394487.5
toll like receptor 4
chr8_+_142834247 0.60 ENST00000522728.5
glycosylphosphatidylinositol anchored molecule like
chr6_+_116511626 0.59 ENST00000368599.4
calcium homeostasis modulator family member 5
chr7_-_138663152 0.55 ENST00000288513.9
SVOP like
chr1_+_152663378 0.54 ENST00000368784.2
late cornified envelope 2D
chr9_-_13279407 0.54 ENST00000546205.5
multiple PDZ domain crumbs cell polarity complex component
chr5_-_43043170 0.54 ENST00000314890.3
annexin A2 receptor
chr6_+_32637419 0.53 ENST00000374949.2
major histocompatibility complex, class II, DQ alpha 1
chr5_+_122311740 0.53 ENST00000506272.5
ENST00000508681.5
ENST00000509154.6
synuclein alpha interacting protein
chr3_+_132597260 0.52 ENST00000249887.3
atypical chemokine receptor 4
chr13_-_48444653 0.51 ENST00000378434.8
lysophosphatidic acid receptor 6
chr19_+_17406099 0.51 ENST00000634942.2
ENST00000634568.1
ENST00000600514.5
BST2 interferon stimulated positive regulator
multivesicular body subunit 12A
chr1_-_205994439 0.51 ENST00000617991.4
RAB7B, member RAS oncogene family
chr9_+_117704382 0.49 ENST00000646089.1
ENST00000355622.8
novel protein
toll like receptor 4
chr19_+_48019726 0.49 ENST00000593413.1
epididymal sperm binding protein 1
chr4_+_75556048 0.49 ENST00000616557.1
ENST00000435974.2
ENST00000311623.9
odontogenesis associated phosphoprotein
chr1_-_60073733 0.49 ENST00000450089.6
chromosome 1 open reading frame 87
chr1_-_60073750 0.48 ENST00000371201.3
chromosome 1 open reading frame 87
chr12_+_93378550 0.47 ENST00000550056.5
ENST00000549992.5
ENST00000548662.5
ENST00000547014.5
nudix hydrolase 4
chr6_+_32637396 0.47 ENST00000395363.5
ENST00000496318.5
ENST00000343139.11
major histocompatibility complex, class II, DQ alpha 1
chrX_+_87517784 0.47 ENST00000373119.9
ENST00000373114.4
kelch like family member 4
chr12_+_93378625 0.46 ENST00000546925.1
nudix hydrolase 4
chr3_-_46464868 0.46 ENST00000417439.5
ENST00000231751.9
ENST00000431944.1
lactotransferrin
chrX_-_52517057 0.46 ENST00000375613.7
X antigen family member 1B
chr5_+_150778733 0.46 ENST00000526627.2
small integral membrane protein 3
chr3_-_39192584 0.46 ENST00000340369.4
ENST00000421646.1
ENST00000396251.1
xin actin binding repeat containing 1
chr20_-_59007210 0.46 ENST00000681175.1
ENST00000681416.1
ENST00000680753.1
ENST00000680995.1
ENST00000680206.1
ENST00000680879.1
ENST00000217131.6
ENST00000680738.1
ENST00000679948.1
ENST00000680880.1
ENST00000681877.1
cathepsin Z
chr12_-_10674013 0.46 ENST00000535345.5
ENST00000542562.5
ENST00000075503.8
serine/threonine/tyrosine kinase 1
chr2_-_189762755 0.44 ENST00000520350.1
ENST00000521630.1
ENST00000264151.10
ENST00000517895.5
O-sialoglycoprotein endopeptidase like 1
chr11_+_59713403 0.44 ENST00000641815.1
syntaxin 3
chr6_-_28252246 0.44 ENST00000377294.3
zinc finger with KRAB and SCAN domains 4
chrX_+_48521788 0.43 ENST00000651615.1
ENST00000495186.6
novel protein
EBP cholestenol delta-isomerase
chr2_-_96740034 0.43 ENST00000264963.9
ENST00000377079.8
lectin, mannose binding 2 like
chr7_+_80646305 0.43 ENST00000426978.5
ENST00000432207.5
CD36 molecule
chr11_+_124115404 0.42 ENST00000361352.9
ENST00000449321.5
ENST00000392748.5
ENST00000392744.4
ENST00000456829.7
von Willebrand factor A domain containing 5A
chr7_+_80646436 0.42 ENST00000419819.2
CD36 molecule
chr16_+_31483002 0.41 ENST00000569576.5
ENST00000330498.4
solute carrier family 5 member 2
chr5_+_150778781 0.41 ENST00000648745.1
small integral membrane protein 3
chrX_+_52495791 0.40 ENST00000375602.2
ENST00000375600.5
X antigen family member 1A
chr16_+_68085861 0.40 ENST00000570212.5
ENST00000562926.5
nuclear factor of activated T cells 3
chrX_-_153673778 0.39 ENST00000340888.8
pregnancy up-regulated nonubiquitous CaM kinase
chr17_-_35986649 0.39 ENST00000622526.1
ENST00000620991.1
ENST00000618404.5
C-C motif chemokine ligand 14
chr19_-_54941610 0.39 ENST00000328092.9
ENST00000590030.5
NLR family pyrin domain containing 7
chr8_-_30082948 0.39 ENST00000521265.5
store-operated calcium entry associated regulatory factor
chr8_-_30083053 0.38 ENST00000256255.11
ENST00000523761.1
store-operated calcium entry associated regulatory factor
chr3_-_184017863 0.38 ENST00000427120.6
ENST00000334444.11
ENST00000392579.6
ENST00000382494.6
ENST00000265586.10
ENST00000446941.2
ATP binding cassette subfamily C member 5
chr8_-_30083110 0.38 ENST00000545648.2
store-operated calcium entry associated regulatory factor
chr1_-_147760592 0.38 ENST00000579774.3
gap junction protein alpha 5
chr5_-_123036664 0.38 ENST00000306442.5
peptidylprolyl isomerase C
chr1_-_24143112 0.37 ENST00000270800.2
interleukin 22 receptor subunit alpha 1
chr19_-_14518383 0.37 ENST00000254322.3
ENST00000595139.2
DnaJ heat shock protein family (Hsp40) member B1
chr19_-_14517425 0.37 ENST00000676577.1
ENST00000677204.1
ENST00000598235.2
DnaJ heat shock protein family (Hsp40) member B1
chr4_-_47914569 0.37 ENST00000507489.2
nuclear transcription factor, X-box binding like 1
chr1_+_220786853 0.37 ENST00000366910.10
mitochondrial amidoxime reducing component 1
chrX_-_153673678 0.37 ENST00000370150.5
pregnancy up-regulated nonubiquitous CaM kinase
chr10_-_96359273 0.37 ENST00000393871.5
ENST00000419479.5
ENST00000393870.3
oligodendrocytic myelin paranodal and inner loop protein
chr6_+_46652914 0.36 ENST00000411689.6
solute carrier family 25 member 27
chr4_-_47914596 0.36 ENST00000381538.7
ENST00000329043.7
nuclear transcription factor, X-box binding like 1
chr6_+_47698538 0.36 ENST00000327753.7
adhesion G protein-coupled receptor F4
chr9_-_21202205 0.35 ENST00000239347.3
interferon alpha 7
chr20_-_25585517 0.35 ENST00000422516.5
ENST00000278886.11
ninein like
chr17_+_50834581 0.35 ENST00000426127.1
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr1_+_152675295 0.35 ENST00000368783.1
late cornified envelope 2C
chr6_+_47698574 0.35 ENST00000283303.3
adhesion G protein-coupled receptor F4
chr2_+_202634960 0.34 ENST00000392238.3
family with sequence similarity 117 member B
chr13_+_39038347 0.34 ENST00000379599.6
ENST00000379600.8
NHL repeat containing 3
chr13_+_39038292 0.34 ENST00000470258.5
NHL repeat containing 3
chr9_+_36036899 0.34 ENST00000377966.4
reversion inducing cysteine rich protein with kazal motifs
chr6_-_170291053 0.34 ENST00000366756.4
delta like canonical Notch ligand 1
chr2_+_189857393 0.34 ENST00000452382.1
PMS1 homolog 1, mismatch repair system component
chr2_+_108786738 0.34 ENST00000412964.6
ENST00000295124.9
coiled-coil domain containing 138
chr6_+_154995258 0.33 ENST00000682666.1
TIAM Rac1 associated GEF 2
chrX_-_112840815 0.33 ENST00000304758.5
ENST00000371959.9
angiomotin
chr13_-_112588125 0.33 ENST00000375669.7
ENST00000464139.5
ENST00000261965.8
tubulin gamma complex associated protein 3
chr19_+_36851645 0.32 ENST00000331800.8
ENST00000612719.4
ENST00000586646.1
zinc finger protein 345
chr22_-_40856565 0.32 ENST00000620312.4
ENST00000216218.8
ST13 Hsp70 interacting protein
chr19_-_4559663 0.32 ENST00000586582.6
semaphorin 6B
chr9_-_94640130 0.32 ENST00000414122.1
fructose-bisphosphatase 1
chr12_+_51238854 0.32 ENST00000549732.6
ENST00000604900.5
DAZ associated protein 2
chr7_+_107660819 0.31 ENST00000644269.2
solute carrier family 26 member 4
chr19_-_17334844 0.30 ENST00000159087.7
anoctamin 8
chr22_+_26621952 0.30 ENST00000354760.4
crystallin beta A4
chr5_+_54517706 0.30 ENST00000326277.5
ENST00000381410.5
ENST00000343017.11
sorting nexin 18
chr1_-_113759464 0.30 ENST00000357783.6
ENST00000369604.6
putative homeodomain transcription factor 1
chr9_+_124853417 0.30 ENST00000613760.4
ENST00000618744.4
ENST00000373574.2
WD repeat domain 38
chr19_-_7040179 0.30 ENST00000381394.9
methyl-CpG binding domain protein 3 like 4
chr13_-_44437214 0.29 ENST00000622051.1
TSC22 domain family member 1
chr6_+_35737028 0.29 ENST00000373869.7
ENST00000373866.4
armadillo repeat containing 12
chr8_+_142834801 0.29 ENST00000220940.2
glycosylphosphatidylinositol anchored molecule like
chr12_-_76348404 0.29 ENST00000650064.2
Bardet-Biedl syndrome 10
chr2_-_58241259 0.29 ENST00000481670.2
ENST00000403676.5
ENST00000427708.6
ENST00000403295.7
ENST00000233741.9
ENST00000446381.5
ENST00000417361.1
ENST00000402135.7
ENST00000449070.5
FA complementation group L
chr1_-_206003385 0.29 ENST00000617070.5
RAB7B, member RAS oncogene family
chr7_+_101817601 0.29 ENST00000292535.12
ENST00000546411.7
ENST00000549414.6
ENST00000550008.6
ENST00000556210.1
cut like homeobox 1
chr6_+_46652968 0.28 ENST00000371347.10
solute carrier family 25 member 27
chr19_+_1354931 0.28 ENST00000591337.7
PWWP domain containing 3A, DNA repair factor
chr3_-_36739791 0.28 ENST00000416516.2
doublecortin like kinase 3
chr19_-_42302292 0.28 ENST00000594989.5
platelet activating factor acetylhydrolase 1b catalytic subunit 3
chr19_-_2051224 0.28 ENST00000309340.11
ENST00000589534.2
ENST00000250896.9
ENST00000589509.5
MAPK interacting serine/threonine kinase 2
chr2_+_216659600 0.28 ENST00000456764.1
insulin like growth factor binding protein 2
chr6_+_35737078 0.28 ENST00000288065.6
armadillo repeat containing 12
chr16_-_88703611 0.28 ENST00000541206.6
ring finger protein 166
chr13_-_44436801 0.28 ENST00000261489.6
TSC22 domain family member 1
chr14_-_106335613 0.28 ENST00000603660.1
immunoglobulin heavy variable 3-30
chr4_-_83109843 0.28 ENST00000411416.6
placenta associated 8
chr7_+_150323239 0.27 ENST00000323078.7
ENST00000493307.1
ENST00000359623.9
leucine rich repeat containing 61
chr1_+_14929734 0.27 ENST00000376028.8
ENST00000400798.6
kazrin, periplakin interacting protein
chr1_-_153963462 0.27 ENST00000368621.5
ENST00000368623.7
ENST00000621013.4
solute carrier family 39 member 1
chr12_+_52274610 0.27 ENST00000423955.7
keratin 86
chr11_+_86302211 0.27 ENST00000533986.5
ENST00000278483.8
heat shock protein nuclear import factor hikeshi
chr2_-_191847068 0.26 ENST00000304141.5
caveolae associated protein 2
chr1_-_145095528 0.26 ENST00000612199.4
ENST00000641863.1
SLIT-ROBO Rho GTPase activating protein 2B
chr19_+_917287 0.26 ENST00000592648.1
ENST00000234371.10
KISS1 receptor
chr13_-_77975513 0.26 ENST00000646948.1
ENST00000435281.2
endothelin receptor type B
novel transcript
chrX_-_153674325 0.26 ENST00000370142.5
ENST00000447676.6
pregnancy up-regulated nonubiquitous CaM kinase
chr19_+_1249870 0.26 ENST00000591446.6
midnolin
chr21_-_32771712 0.26 ENST00000331923.9
PAX3 and PAX7 binding protein 1
chr1_-_235866916 0.26 ENST00000389794.7
lysosomal trafficking regulator
chr9_-_21207143 0.26 ENST00000357374.2
interferon alpha 10
chrX_+_136197039 0.25 ENST00000370683.6
four and a half LIM domains 1
chr21_-_30372265 0.25 ENST00000399889.4
keratin associated protein 13-2
chr12_+_103930332 0.25 ENST00000681861.1
ENST00000550595.2
ENST00000680762.1
ENST00000614327.2
ENST00000681949.1
ENST00000299767.10
heat shock protein 90 beta family member 1
chr19_+_13151975 0.25 ENST00000588173.1
immediate early response 2
chr4_-_103099811 0.25 ENST00000504285.5
ENST00000296424.9
3-hydroxybutyrate dehydrogenase 2
chr19_-_54364908 0.25 ENST00000391742.7
leukocyte associated immunoglobulin like receptor 1
chr20_+_33283205 0.25 ENST00000253354.2
BPI fold containing family B member 1
chr1_-_153963505 0.25 ENST00000356205.9
ENST00000537590.5
solute carrier family 39 member 1
chr4_-_83485065 0.24 ENST00000515303.2
ENST00000321945.12
ENST00000503217.2
abraxas 1, BRCA1 A complex subunit
chr6_+_87472925 0.24 ENST00000369556.7
ENST00000369557.9
ENST00000369552.9
solute carrier family 35 member A1
chr6_-_84763437 0.24 ENST00000606784.5
ENST00000606325.5
T-box transcription factor 18
chr19_-_7058640 0.24 ENST00000333843.8
methyl-CpG binding domain protein 3 like 3
chr20_+_64066211 0.24 ENST00000458442.1
transcription elongation factor A2
chr17_+_80220406 0.24 ENST00000573809.5
ENST00000361193.8
ENST00000574967.5
ENST00000576126.5
ENST00000411502.7
ENST00000546047.6
ENST00000572725.5
solute carrier family 26 member 11
chr10_-_99913971 0.24 ENST00000543621.6
dynamin binding protein
chrX_-_154295085 0.24 ENST00000617225.4
ENST00000619903.4
testis expressed 28
chr18_-_35290184 0.24 ENST00000589178.5
ENST00000592278.1
ENST00000333206.10
ENST00000592211.1
ENST00000420878.7
ENST00000610712.1
ENST00000586922.2
zinc finger and SCAN domain containing 30
novel transcript
chr9_-_21368057 0.24 ENST00000449498.2
interferon alpha 13
chr11_-_102452758 0.23 ENST00000398136.7
ENST00000361236.7
transmembrane protein 123
chr2_-_127642131 0.23 ENST00000426981.5
LIM zinc finger domain containing 2
chr1_-_151372683 0.23 ENST00000458566.5
ENST00000447402.7
ENST00000426705.6
ENST00000368868.10
selenium binding protein 1
chr2_+_87748087 0.23 ENST00000359481.9
plasminogen like B2
chr10_+_133453936 0.23 ENST00000640237.1
scavenger receptor family member expressed on T cells 1
chr9_-_34710069 0.23 ENST00000378792.1
ENST00000259607.7
C-C motif chemokine ligand 21
chr19_-_51020019 0.23 ENST00000309958.7
kallikrein related peptidase 10
chr2_-_87021844 0.23 ENST00000355705.4
ENST00000409310.6
plasminogen like B1
chr19_-_7702124 0.23 ENST00000597921.6
Fc fragment of IgE receptor II
chr17_-_61928005 0.23 ENST00000444766.7
integrator complex subunit 2
chr6_-_38639898 0.23 ENST00000481247.6
BTB domain containing 9
chr4_+_89111521 0.23 ENST00000603357.3
tigger transposable element derived 2
chr14_+_75522427 0.22 ENST00000286639.8
basic leucine zipper ATF-like transcription factor
chrX_-_30308333 0.22 ENST00000378963.1
nuclear receptor subfamily 0 group B member 1
chr2_-_218002988 0.22 ENST00000682258.1
ENST00000446903.5
tensin 1
chr19_-_42302690 0.22 ENST00000596265.5
platelet activating factor acetylhydrolase 1b catalytic subunit 3
chr8_+_22995831 0.22 ENST00000522948.5
Rho related BTB domain containing 2
chr11_+_61752603 0.22 ENST00000278836.10
myelin regulatory factor
chr19_+_1248553 0.22 ENST00000586757.5
ENST00000300952.6
ENST00000682408.1
midnolin
chr22_+_40857076 0.22 ENST00000614001.1
ENST00000357137.9
X-prolyl aminopeptidase 3
chr1_-_235866867 0.22 ENST00000389793.7
lysosomal trafficking regulator
chr8_+_95024977 0.22 ENST00000396124.9
NADH:ubiquinone oxidoreductase complex assembly factor 6
chr2_+_102473219 0.22 ENST00000295269.5
solute carrier family 9 member A4
chr2_-_240025299 0.22 ENST00000404554.5
ENST00000407129.3
ENST00000307300.8
ENST00000678455.1
ENST00000444548.6
ENST00000252711.7
ENST00000620965.5
ENST00000443626.5
NADH:ubiquinone oxidoreductase subunit A10
chr2_-_200864561 0.22 ENST00000434813.3
CDC like kinase 1
chr19_-_42302576 0.22 ENST00000262890.8
platelet activating factor acetylhydrolase 1b catalytic subunit 3
chr1_+_7961894 0.22 ENST00000377491.5
ENST00000377488.5
Parkinsonism associated deglycase
chr14_+_39265278 0.22 ENST00000554392.5
ENST00000555716.5
ENST00000341749.7
ENST00000557038.5
MIA SH3 domain ER export factor 2
chr20_+_3888915 0.21 ENST00000316562.9
ENST00000495692.5
pantothenate kinase 2
chr12_+_119668109 0.21 ENST00000229328.10
ENST00000630317.1
protein kinase AMP-activated non-catalytic subunit beta 1
chr11_-_59810750 0.21 ENST00000300151.5
mitochondrial ribosomal protein L16
chr3_+_119703001 0.21 ENST00000273390.9
ENST00000463700.1
ENST00000648112.1
cilia and flagella associated protein 91
novel protein
chrX_-_75523011 0.21 ENST00000373367.8
zinc finger DHHC-type palmitoyltransferase 15
chr12_+_119667859 0.21 ENST00000541640.5
protein kinase AMP-activated non-catalytic subunit beta 1
chr17_-_78577383 0.21 ENST00000389840.7
dynein axonemal heavy chain 17
chr15_-_72197772 0.21 ENST00000309731.12
GRAM domain containing 2A
chr20_+_63235883 0.21 ENST00000342412.10
baculoviral IAP repeat containing 7
chr22_-_26565362 0.21 ENST00000398110.6
tyrosylprotein sulfotransferase 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.4 1.1 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.3 0.9 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.3 1.1 GO:1904349 regulation of small intestine smooth muscle contraction(GO:1904347) positive regulation of small intestine smooth muscle contraction(GO:1904349) small intestine smooth muscle contraction(GO:1990770)
0.2 1.6 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.2 0.8 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.2 0.9 GO:0033058 directional locomotion(GO:0033058)
0.2 0.6 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.2 0.5 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 0.9 GO:0015961 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.4 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.6 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.1 0.4 GO:0035922 pulmonary valve formation(GO:0003193) foramen ovale closure(GO:0035922) regulation of bundle of His cell action potential(GO:0098905)
0.1 0.5 GO:1900191 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229) positive regulation of chondrocyte proliferation(GO:1902732)
0.1 0.2 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
0.1 0.3 GO:0045608 negative regulation of auditory receptor cell differentiation(GO:0045608)
0.1 0.3 GO:1903181 enzyme active site formation(GO:0018307) neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) detoxification of mercury ion(GO:0050787) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.1 0.5 GO:0019075 virus maturation(GO:0019075)
0.1 0.8 GO:2000332 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.5 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1 0.3 GO:0031247 actin rod assembly(GO:0031247)
0.1 0.3 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.1 0.2 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.1 0.6 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.1 0.4 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.1 1.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.2 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.5 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.3 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.1 0.2 GO:0002368 B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.2 GO:0061386 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.2 GO:0002892 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
0.1 0.3 GO:0035645 enteric smooth muscle cell differentiation(GO:0035645)
0.1 0.2 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.1 0.1 GO:0001812 regulation of type I hypersensitivity(GO:0001810) positive regulation of type I hypersensitivity(GO:0001812) type I hypersensitivity(GO:0016068)
0.0 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.1 GO:0070676 intralumenal vesicle formation(GO:0070676) negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.1 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.1 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.2 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.3 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.1 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.0 0.4 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.6 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.3 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.2 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.2 GO:0030576 Cajal body organization(GO:0030576)
0.0 0.1 GO:1901389 regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
0.0 0.3 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.0 0.2 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.9 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 0.3 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.1 GO:0018032 protein amidation(GO:0018032)
0.0 0.1 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0 0.1 GO:2000612 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.0 0.3 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.0 0.1 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.1 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.0 0.3 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.1 GO:0052314 phthalate metabolic process(GO:0018963) epinephrine biosynthetic process(GO:0042418) phytoalexin metabolic process(GO:0052314)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.3 GO:0035973 aggrephagy(GO:0035973)
0.0 0.6 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.2 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.2 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.0 0.2 GO:0070943 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.0 0.1 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.0 0.1 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.2 GO:0042428 serotonin metabolic process(GO:0042428)
0.0 0.1 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.1 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.1 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.0 0.3 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.1 GO:0036100 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.4 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.2 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.0 0.6 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.4 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.2 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.1 GO:0048669 microglia differentiation(GO:0014004) microglia development(GO:0014005) collateral sprouting in absence of injury(GO:0048669) smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.1 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.0 0.3 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.2 GO:2000580 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.3 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.2 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.3 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.1 GO:2000653 chromatin reprogramming in the zygote(GO:0044725) regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536) regulation of genetic imprinting(GO:2000653)
0.0 0.0 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.3 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 1.0 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.0 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.5 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.4 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.1 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.1 GO:0015811 L-cystine transport(GO:0015811) basic amino acid transmembrane transport(GO:1990822)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.0 GO:2000452 CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.0 0.2 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.2 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.9 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0032202 telomere assembly(GO:0032202)
0.0 0.5 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.2 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.1 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.9 GO:0007566 embryo implantation(GO:0007566)
0.0 1.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.4 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.0 0.1 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.1 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.0 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0 0.0 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.0 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.4 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.5 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.2 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.2 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.1 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.0 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.4 GO:0043304 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 0.2 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.0 0.2 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.3 GO:0043303 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.0 0.3 GO:0010226 response to lithium ion(GO:0010226)
0.0 0.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.3 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.4 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 0.5 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.3 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.1 0.4 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.1 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.1 GO:1990913 sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917)
0.0 0.3 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 1.2 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0035363 histone locus body(GO:0035363)
0.0 1.8 GO:0099738 cell cortex region(GO:0099738)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.5 GO:0005922 connexon complex(GO:0005922)
0.0 2.4 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.2 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.4 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.2 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.4 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0000247 C-8 sterol isomerase activity(GO:0000247) cholestenol delta-isomerase activity(GO:0047750)
0.2 0.9 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.2 0.9 GO:0052845 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.1 0.6 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 1.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.4 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 0.8 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.3 GO:0016608 growth hormone-releasing hormone activity(GO:0016608)
0.1 0.4 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.4 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.1 0.3 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.3 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 0.9 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.3 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.1 0.4 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.3 GO:1903135 superoxide dismutase copper chaperone activity(GO:0016532) cupric ion binding(GO:1903135)
0.1 0.2 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.1 0.5 GO:0019863 IgE binding(GO:0019863)
0.1 0.8 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.8 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.5 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.2 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.4 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.3 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.7 GO:1901567 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.2 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.3 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.6 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.8 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.1 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.1 GO:0032093 SAM domain binding(GO:0032093)
0.0 1.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.0 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.1 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.6 GO:0070330 aromatase activity(GO:0070330)
0.0 0.1 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.0 0.3 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 1.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.7 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.4 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0008430 selenium binding(GO:0008430)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172) DNA-methyltransferase activity(GO:0009008)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 1.1 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.6 GO:0019956 chemokine binding(GO:0019956)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0034617 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) tetrahydrobiopterin binding(GO:0034617)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.0 GO:0004074 biliverdin reductase activity(GO:0004074)
0.0 0.1 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.3 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.0 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) protein phosphatase 2B binding(GO:0030346)
0.0 0.0 GO:0032428 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.9 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.6 PID IL12 2PATHWAY IL12-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 0.9 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 2.0 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.9 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.8 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.0 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 2.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.6 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.6 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.0 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 0.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.1 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants