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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for HSF4

Z-value: 0.49

Motif logo

Transcription factors associated with HSF4

Gene Symbol Gene ID Gene Info
ENSG00000102878.18 HSF4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HSF4hg38_v1_chr16_+_67164730_671647680.291.6e-01Click!

Activity profile of HSF4 motif

Sorted Z-values of HSF4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HSF4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_+_227813834 1.97 ENST00000358813.5
ENST00000409189.7
C-C motif chemokine ligand 20
chr5_+_119354771 1.18 ENST00000503646.1
TNF alpha induced protein 8
chr6_+_127577168 0.87 ENST00000329722.8
chromosome 6 open reading frame 58
chr9_+_33025265 0.86 ENST00000330899.5
DnaJ heat shock protein family (Hsp40) member A1
chr6_+_4889992 0.72 ENST00000343762.5
chromodomain Y like
chr15_-_58065734 0.67 ENST00000347587.7
aldehyde dehydrogenase 1 family member A2
chr15_-_58065703 0.66 ENST00000249750.9
aldehyde dehydrogenase 1 family member A2
chrX_-_155334580 0.64 ENST00000369449.7
ENST00000321926.4
chloride intracellular channel 2
chr19_-_17847962 0.63 ENST00000458235.7
ENST00000534444.1
Janus kinase 3
chr15_-_58065870 0.62 ENST00000537372.5
aldehyde dehydrogenase 1 family member A2
chr7_-_1160144 0.61 ENST00000397083.6
ENST00000401903.5
ENST00000316495.8
zinc finger AN1-type containing 2A
chr18_+_59899988 0.60 ENST00000316660.7
ENST00000269518.9
phorbol-12-myristate-13-acetate-induced protein 1
chr2_-_100142575 0.57 ENST00000317233.8
ENST00000672204.1
ENST00000416492.5
ENST00000672857.1
ENST00000672756.2
AF4/FMR2 family member 3
chr12_-_57111338 0.53 ENST00000538913.6
ENST00000537215.6
ENST00000300134.8
ENST00000454075.7
ENST00000640254.2
ENST00000553275.1
ENST00000553533.2
signal transducer and activator of transcription 6
chrX_+_109536641 0.51 ENST00000372107.5
nuclear transport factor 2 like export factor 2
chr11_+_64186219 0.48 ENST00000543847.1
stress induced phosphoprotein 1
chr20_+_57329801 0.46 ENST00000371263.8
ENST00000345868.8
ENST00000371260.8
ENST00000418127.5
SPO11 initiator of meiotic double stranded breaks
chr8_+_142834801 0.45 ENST00000220940.2
glycosylphosphatidylinositol anchored molecule like
chr21_-_30372265 0.45 ENST00000399889.4
keratin associated protein 13-2
chr21_+_33403466 0.44 ENST00000405436.5
interferon gamma receptor 2
chr20_-_36951637 0.43 ENST00000646066.1
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
chr20_-_36951665 0.43 ENST00000643918.1
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
chr20_+_59628609 0.42 ENST00000541461.5
phosphatase and actin regulator 3
chr19_-_55160668 0.41 ENST00000588076.1
dynein axonemal assembly factor 3
chr19_-_51390528 0.40 ENST00000570516.1
ENST00000574814.2
chromosome 19 open reading frame 84
chr20_-_36951837 0.40 ENST00000262878.5
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
chr17_-_76726453 0.39 ENST00000585429.1
jumonji domain containing 6, arginine demethylase and lysine hydroxylase
chrX_-_153673778 0.39 ENST00000340888.8
pregnancy up-regulated nonubiquitous CaM kinase
chr1_+_212608628 0.39 ENST00000613954.4
ENST00000341491.9
ENST00000366985.5
activating transcription factor 3
chr6_+_31715339 0.38 ENST00000375824.1
ENST00000375825.7
lymphocyte antigen 6 family member G6D
chr7_-_100896123 0.37 ENST00000428317.7
acetylcholinesterase (Cartwright blood group)
chr11_+_107928394 0.37 ENST00000320578.3
RAB39A, member RAS oncogene family
chr20_-_36951701 0.36 ENST00000646673.2
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
chr10_-_73096850 0.36 ENST00000307116.6
ENST00000373008.6
ENST00000394890.7
prolyl 4-hydroxylase subunit alpha 1
chr5_+_10250216 0.34 ENST00000515390.5
chaperonin containing TCP1 subunit 5
chr19_-_344786 0.34 ENST00000264819.7
MIER family member 2
chr9_+_34989641 0.33 ENST00000453597.8
ENST00000312316.9
ENST00000458263.6
ENST00000537321.5
ENST00000682809.1
ENST00000684748.1
DnaJ heat shock protein family (Hsp40) member B5
chr5_+_173144442 0.33 ENST00000231668.13
ENST00000351486.10
ENST00000352523.10
ENST00000393770.4
BCL2 interacting protein 1
chr11_+_111245725 0.33 ENST00000280325.7
chromosome 11 open reading frame 53
chr11_+_64186163 0.32 ENST00000305218.9
ENST00000538945.5
stress induced phosphoprotein 1
chr21_+_42974510 0.32 ENST00000432907.6
ENST00000291547.10
PBX/knotted 1 homeobox 1
chr9_-_135699473 0.32 ENST00000425225.2
ENST00000298466.9
spermatogenesis and oogenesis specific basic helix-loop-helix 1
chr7_+_157336961 0.30 ENST00000429029.6
DnaJ heat shock protein family (Hsp40) member B6
chr2_+_200306648 0.29 ENST00000409140.8
spermatogenesis associated serine rich 2 like
chr11_-_10568650 0.29 ENST00000256178.8
lymphatic vessel endothelial hyaluronan receptor 1
chrX_+_109536832 0.28 ENST00000372106.6
nuclear transport factor 2 like export factor 2
chr18_+_46917561 0.28 ENST00000683218.1
katanin catalytic subunit A1 like 2
chr20_-_44960348 0.27 ENST00000372813.4
translocase of outer mitochondrial membrane 34
chr11_+_67240047 0.27 ENST00000530342.2
lysine demethylase 2A
chr17_-_76726590 0.27 ENST00000397625.9
ENST00000445478.6
jumonji domain containing 6, arginine demethylase and lysine hydroxylase
chr2_+_200305976 0.26 ENST00000358677.9
spermatogenesis associated serine rich 2 like
chr11_-_111911759 0.26 ENST00000650687.2
crystallin alpha B
chr3_+_39467598 0.26 ENST00000428261.5
ENST00000420739.5
ENST00000415443.5
ENST00000447324.5
ENST00000383754.7
myelin associated oligodendrocyte basic protein
chr17_-_42016680 0.25 ENST00000674497.1
DnaJ heat shock protein family (Hsp40) member C7
chr11_-_111910790 0.25 ENST00000533280.6
crystallin alpha B
chr11_-_111910888 0.25 ENST00000525823.1
ENST00000528961.6
crystallin alpha B
chr3_+_39467672 0.25 ENST00000436143.6
ENST00000441980.6
ENST00000682069.1
ENST00000311042.10
myelin associated oligodendrocyte basic protein
chr11_-_111910830 0.24 ENST00000526167.5
ENST00000651650.1
crystallin alpha B
chr18_-_74147816 0.24 ENST00000419743.7
ENST00000582526.1
F-box protein 15
chr8_-_51809414 0.24 ENST00000356297.5
peroxidasin like
chr17_+_34319427 0.23 ENST00000394620.2
C-C motif chemokine ligand 8
chr6_-_32371872 0.23 ENST00000527965.5
ENST00000532023.5
ENST00000447241.6
ENST00000534588.1
testis expressed basic protein 1
chr6_-_32371897 0.23 ENST00000442822.6
ENST00000375015.8
ENST00000533191.5
testis expressed basic protein 1
chr10_+_24239181 0.22 ENST00000438429.5
KIAA1217
chr4_+_41256921 0.22 ENST00000284440.9
ENST00000508768.5
ENST00000512788.1
ubiquitin C-terminal hydrolase L1
chr6_-_32371912 0.22 ENST00000612031.4
testis expressed basic protein 1
chr1_+_28259473 0.22 ENST00000253063.4
sestrin 2
chr4_-_158723355 0.22 ENST00000307720.4
peptidylprolyl isomerase D
chr12_-_9733083 0.21 ENST00000542530.5
C-type lectin like 1
chr11_-_10568571 0.21 ENST00000529598.1
lymphatic vessel endothelial hyaluronan receptor 1
chr7_+_130381092 0.21 ENST00000484324.1
carboxypeptidase A1
chr20_+_37521206 0.21 ENST00000346199.3
ENST00000647955.1
ENST00000649451.1
ENST00000649697.1
ENST00000649309.1
neuronatin
chr2_+_85539158 0.21 ENST00000306434.8
methionine adenosyltransferase 2A
chr11_+_65386611 0.20 ENST00000531296.1
ENST00000533782.5
ENST00000355991.9
ENST00000317568.10
ENST00000416776.6
ENST00000526201.1
FERM domain containing 8
chr6_+_42564060 0.20 ENST00000372903.6
ubiquitin protein ligase E3 component n-recognin 2
chr7_+_130380339 0.20 ENST00000481342.5
ENST00000604896.5
ENST00000011292.8
carboxypeptidase A1
chr1_+_26921715 0.20 ENST00000321265.10
nuclear distribution C, dynein complex regulator
chr1_+_1308587 0.20 ENST00000379031.10
pseudouridine synthase like 1
chr1_-_156338226 0.18 ENST00000496684.6
ENST00000368259.6
ENST00000472765.6
ENST00000295688.8
ENST00000533194.5
ENST00000478640.6
chaperonin containing TCP1 subunit 3
chr11_+_193078 0.18 ENST00000342878.3
secretoglobin family 1C member 1
chr3_+_130894157 0.18 ENST00000504948.5
ENST00000513801.5
ENST00000505072.5
ATPase secretory pathway Ca2+ transporting 1
chr1_+_156338619 0.18 ENST00000481479.5
ENST00000368252.5
ENST00000466306.5
ENST00000368251.1
TSSK6 activating cochaperone
chr17_-_76726753 0.18 ENST00000617192.4
jumonji domain containing 6, arginine demethylase and lysine hydroxylase
chr3_+_1093002 0.18 ENST00000446702.7
contactin 6
chr15_+_43800586 0.18 ENST00000442995.4
ENST00000458412.2
huntingtin interacting protein K
chr3_+_130894382 0.18 ENST00000509662.5
ENST00000328560.12
ENST00000428331.6
ENST00000359644.7
ENST00000422190.6
ATPase secretory pathway Ca2+ transporting 1
chr19_+_41003946 0.18 ENST00000593831.1
cytochrome P450 family 2 subfamily B member 6
chr1_+_53459391 0.17 ENST00000371445.3
DMRT like family B with proline rich C-terminal 1
chrX_-_103688033 0.17 ENST00000434230.5
ENST00000418819.5
ENST00000360458.5
mortality factor 4 like 2
chr1_-_205935822 0.17 ENST00000340781.8
solute carrier family 26 member 9
chr19_-_18538371 0.17 ENST00000596015.1
FKBP prolyl isomerase 8
chr11_-_47848539 0.16 ENST00000526870.1
nucleoporin 160
chr14_-_102087034 0.16 ENST00000216281.13
ENST00000553585.5
heat shock protein 90 alpha family class A member 1
chr20_+_18813777 0.16 ENST00000377428.4
SCP2 sterol binding domain containing 1
chr17_+_7355123 0.16 ENST00000389982.8
ENST00000576060.6
ENST00000330767.4
transmembrane protein 95
chr3_+_130893959 0.16 ENST00000508532.5
ENST00000533801.6
ATPase secretory pathway Ca2+ transporting 1
chr17_+_137569 0.16 ENST00000595228.4
secretoglobin family 1C member 2
chr20_-_23826721 0.15 ENST00000304725.3
cystatin SA
chr4_+_22692906 0.15 ENST00000613293.4
ENST00000610628.4
glucosylceramidase beta 3 (gene/pseudogene)
chr1_+_154974672 0.15 ENST00000308987.6
ENST00000368436.1
CDC28 protein kinase regulatory subunit 1B
chr8_+_142700465 0.15 ENST00000522591.1
lymphocyte antigen 6 family member K
chr20_-_63463843 0.15 ENST00000637193.1
potassium voltage-gated channel subfamily Q member 2
chr22_+_29268316 0.15 ENST00000414183.6
ENST00000333395.10
ENST00000455726.5
ENST00000332035.10
EWS RNA binding protein 1
chr13_+_94601830 0.14 ENST00000376958.5
G protein-coupled receptor 180
chr1_+_156338455 0.14 ENST00000368253.6
ENST00000470342.5
ENST00000368254.6
TSSK6 activating cochaperone
chr8_+_142700095 0.14 ENST00000292430.10
ENST00000518841.5
ENST00000519387.1
lymphocyte antigen 6 family member K
chr3_+_130894050 0.14 ENST00000510168.6
ATPase secretory pathway Ca2+ transporting 1
chrX_-_103688090 0.14 ENST00000433176.6
mortality factor 4 like 2
chr1_+_154974653 0.14 ENST00000368439.5
CDC28 protein kinase regulatory subunit 1B
chr12_+_69738853 0.14 ENST00000247833.12
ENST00000378815.10
ENST00000483530.6
RAB3A interacting protein
chr12_-_110502065 0.14 ENST00000447578.6
ENST00000546588.1
ENST00000360579.11
ENST00000549578.6
ENST00000549970.5
VPS29 retromer complex component
chr19_-_49061997 0.13 ENST00000593537.1
neurotrophin 4
chr9_-_135499846 0.13 ENST00000429260.7
chromosome 9 open reading frame 116
chr3_+_133400046 0.13 ENST00000302334.3
beaded filament structural protein 2
chr22_+_29268248 0.12 ENST00000436425.5
ENST00000447973.5
ENST00000397938.7
ENST00000406548.5
ENST00000437155.6
ENST00000415761.5
ENST00000331029.11
EWS RNA binding protein 1
chr1_-_26306576 0.12 ENST00000421827.2
ENST00000374215.5
ENST00000374223.5
ENST00000357089.8
ENST00000314675.11
ENST00000423664.5
ENST00000374221.7
UBX domain protein 11
chr11_-_47848313 0.12 ENST00000530326.5
ENST00000528071.5
nucleoporin 160
chr11_+_66002475 0.12 ENST00000312175.7
ENST00000533166.5
BAF nuclear assembly factor 1
chr9_-_4666347 0.12 ENST00000381890.9
ENST00000682582.1
spermatogenesis associated 6 like
chr21_+_43728851 0.12 ENST00000327574.4
pyridoxal kinase
chr15_-_89211803 0.12 ENST00000563254.1
retinaldehyde binding protein 1
chr2_-_68952880 0.11 ENST00000481498.1
ENST00000328895.9
gastrokine 2
chr11_-_66002123 0.11 ENST00000532707.5
ENST00000526451.5
ENST00000312234.6
ENST00000533544.6
ENST00000530462.5
ENST00000525767.5
ENST00000529964.5
ENST00000527249.5
eukaryotic translation initiation factor 1A domain containing
chr12_-_9733292 0.11 ENST00000621400.4
ENST00000327839.3
C-type lectin like 1
chr11_+_66002225 0.11 ENST00000445560.6
ENST00000530204.1
BAF nuclear assembly factor 1
chrX_-_107000185 0.11 ENST00000355610.9
MORC family CW-type zinc finger 4
chr3_+_101724602 0.11 ENST00000341893.8
centrosomal protein 97
chr6_+_36197356 0.11 ENST00000446974.1
ENST00000454960.1
bromodomain and PHD finger containing 3
chr11_-_86672419 0.11 ENST00000524826.7
ENST00000532471.1
malic enzyme 3
chr16_-_9943182 0.10 ENST00000535259.6
glutamate ionotropic receptor NMDA type subunit 2A
chr4_-_76421121 0.10 ENST00000682701.1
coiled-coil domain containing 158
chr8_+_37736667 0.10 ENST00000518586.5
ENST00000335171.10
ENST00000521644.5
ER lipid raft associated 2
chr2_-_61888570 0.10 ENST00000394440.8
ENST00000544079.2
chaperonin containing TCP1 subunit 4
chr1_-_173669835 0.10 ENST00000333279.3
ankyrin repeat domain 45
chr9_+_69123009 0.10 ENST00000647986.1
tight junction protein 2
chr22_+_32475257 0.10 ENST00000397426.5
F-box protein 7
chr7_+_142670734 0.10 ENST00000390398.3
T cell receptor beta variable 25-1
chr7_+_157336988 0.10 ENST00000262177.9
ENST00000417758.5
ENST00000443280.5
DnaJ heat shock protein family (Hsp40) member B6
chr8_+_61287950 0.09 ENST00000519846.5
ENST00000325897.5
ENST00000523868.2
ENST00000518592.5
clavesin 1
chr5_+_40909490 0.09 ENST00000313164.10
complement C7
chr15_-_85794902 0.09 ENST00000337975.6
kelch like family member 25
chr11_-_47848467 0.09 ENST00000378460.6
nucleoporin 160
chr9_-_33025088 0.09 ENST00000436040.7
aprataxin
chr5_+_10250272 0.08 ENST00000280326.9
ENST00000625723.1
chaperonin containing TCP1 subunit 5
chr6_-_76072654 0.08 ENST00000369950.8
ENST00000611179.4
ENST00000369963.5
interphotoreceptor matrix proteoglycan 1
chr17_-_63773534 0.08 ENST00000403162.7
ENST00000582252.1
ENST00000225726.10
coiled-coil domain containing 47
chr14_-_56810448 0.08 ENST00000339475.10
ENST00000555006.5
ENST00000672264.2
ENST00000554559.5
ENST00000555804.1
orthodenticle homeobox 2
chr9_-_134917872 0.08 ENST00000616356.4
ENST00000371806.4
ficolin 1
chr9_-_4666495 0.08 ENST00000475086.5
spermatogenesis associated 6 like
chr5_-_140673568 0.08 ENST00000542735.2
DND microRNA-mediated repression inhibitor 1
chr7_-_151410677 0.08 ENST00000621812.2
ENST00000477459.5
WD repeat domain 86
chr7_+_5879827 0.07 ENST00000416608.5
oncomodulin
chr1_+_21468442 0.07 ENST00000619554.1
NBPF member 3
chr12_+_69585434 0.07 ENST00000299300.11
ENST00000544368.6
chaperonin containing TCP1 subunit 2
chr10_-_88851809 0.07 ENST00000371930.5
ankyrin repeat domain 22
chr2_-_197499826 0.07 ENST00000439605.2
ENST00000388968.8
ENST00000418022.2
heat shock protein family D (Hsp60) member 1
chr11_+_66002754 0.07 ENST00000527348.1
BAF nuclear assembly factor 1
chr1_-_152414256 0.07 ENST00000271835.3
cornulin
chr12_-_114406133 0.07 ENST00000405440.7
T-box transcription factor 5
chr12_+_110502200 0.07 ENST00000409246.5
ENST00000392672.8
ENST00000409425.5
RAD9 checkpoint clamp component B
chr11_-_90223059 0.07 ENST00000457199.6
ENST00000530765.5
cysteine and histidine rich domain containing 1
chr2_-_68252482 0.07 ENST00000234310.8
protein phosphatase 3 regulatory subunit B, alpha
chr3_-_185938006 0.07 ENST00000342294.4
ENST00000453386.7
ENST00000382191.4
transformer 2 beta homolog
chr20_-_23751256 0.07 ENST00000398402.1
cystatin SN
chr20_+_10034963 0.07 ENST00000378392.6
ankyrin repeat and EF-hand domain containing 1
chr6_+_44246166 0.06 ENST00000620073.4
heat shock protein 90 alpha family class B member 1
chr2_-_197499857 0.06 ENST00000428204.6
ENST00000678170.1
ENST00000676933.1
ENST00000678621.1
heat shock protein family D (Hsp60) member 1
chr12_+_110502307 0.06 ENST00000409778.7
ENST00000409300.6
RAD9 checkpoint clamp component B
chr1_-_244863085 0.06 ENST00000440865.2
heterogeneous nuclear ribonucleoprotein U
chr10_+_10798570 0.06 ENST00000638035.1
ENST00000636488.1
CUGBP Elav-like family member 2
chr1_-_25905989 0.06 ENST00000399728.5
stathmin 1
chr19_+_859654 0.06 ENST00000592860.2
ENST00000327726.11
complement factor D
chr2_-_208129824 0.06 ENST00000282141.4
crystallin gamma C
chr17_+_47323941 0.06 ENST00000331493.7
ENST00000519772.5
ENST00000517484.5
EF-hand calcium binding domain 13
chr9_-_33025052 0.06 ENST00000673248.1
aprataxin
chr6_+_42563981 0.06 ENST00000372899.6
ENST00000372901.2
ubiquitin protein ligase E3 component n-recognin 2
chr1_-_156282799 0.05 ENST00000361813.5
SMG5 nonsense mediated mRNA decay factor
chr20_+_10035029 0.05 ENST00000378380.4
ankyrin repeat and EF-hand domain containing 1
chrX_-_107982370 0.05 ENST00000302917.1
testis expressed 13B
chr3_+_136957948 0.05 ENST00000329582.9
interleukin 20 receptor subunit beta
chr11_-_111923722 0.05 ENST00000527950.5
crystallin alpha B
chr20_+_56533246 0.05 ENST00000371325.1
family with sequence similarity 209 member B
chr14_-_56810380 0.05 ENST00000672125.1
ENST00000673481.1
orthodenticle homeobox 2
chrX_-_153724343 0.05 ENST00000442093.5
ENST00000345046.12
ENST00000645377.1
ENST00000672675.1
ENST00000647529.1
ENST00000429550.5
B cell receptor associated protein 31
chr7_+_146116772 0.05 ENST00000361727.8
contactin associated protein 2
chr12_-_56636318 0.04 ENST00000549506.5
ENST00000379441.7
ENST00000551812.5
bromodomain adjacent to zinc finger domain 2A
chr1_-_6393339 0.04 ENST00000608083.5
acyl-CoA thioesterase 7
chr1_-_6393750 0.04 ENST00000545482.5
ENST00000361521.9
acyl-CoA thioesterase 7
chr14_-_22919124 0.04 ENST00000555209.5
ENST00000554256.5
ENST00000557403.5
ENST00000359890.8
ENST00000557549.5
ENST00000555676.5
ENST00000557571.5
ENST00000557464.5
ENST00000554618.5
ENST00000556862.5
ENST00000555722.5
ENST00000346528.9
ENST00000542016.6
ENST00000399922.6
ENST00000557227.5
RNA binding motif protein 23
chr19_-_6720641 0.04 ENST00000245907.11
complement C3
chr1_-_53238485 0.04 ENST00000371466.4
ENST00000371470.8
mago homolog, exon junction complex subunit
chr4_+_76011171 0.04 ENST00000513353.5
ENST00000341029.9
ADP-ribosyltransferase 3 (inactive)
chrX_-_153724044 0.04 ENST00000423827.5
ENST00000458587.8
B cell receptor associated protein 31
chr17_-_78577383 0.04 ENST00000389840.7
dynein axonemal heavy chain 17
chr10_-_60572599 0.04 ENST00000503366.5
ankyrin 3
chr16_-_23557331 0.04 ENST00000563232.1
ENST00000449606.7
glutamyl-tRNA synthetase 2, mitochondrial
chr1_-_60073750 0.04 ENST00000371201.3
chromosome 1 open reading frame 87
chr2_-_208124514 0.04 ENST00000264376.5
crystallin gamma D
chr2_+_202265721 0.04 ENST00000264279.10
NOP58 ribonucleoprotein
chr4_-_94342826 0.04 ENST00000295256.10
hematopoietic prostaglandin D synthase

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.3 0.8 GO:0070077 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine(GO:0018395) histone arginine demethylation(GO:0070077) histone H3-R2 demethylation(GO:0070078) histone H4-R3 demethylation(GO:0070079)
0.2 2.0 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 1.6 GO:0006203 dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061)
0.2 0.6 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.1 0.5 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 0.4 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.4 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.5 GO:0000706 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.1 0.7 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 1.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.2 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.0 0.4 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.0 0.1 GO:0045041 B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.2 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0048867 stem cell fate determination(GO:0048867)
0.0 0.5 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.2 GO:0043335 protein unfolding(GO:0043335)
0.0 0.6 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.9 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.6 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.0 0.5 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.1 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.1 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.1 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0 0.4 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.1 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.0 0.6 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.2 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:1901389 regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
0.0 0.2 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.1 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.1 GO:0033058 directional locomotion(GO:0033058)
0.0 0.1 GO:1900535 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 0.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.0 GO:0001794 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
0.0 0.2 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.4 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.4 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.1 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.4 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.4 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.9 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 0.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 1.0 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.8 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.1 GO:0097409 glial cytoplasmic inclusion(GO:0097409) classical Lewy body(GO:0097414) Lewy neurite(GO:0097462) Lewy body corona(GO:1990038)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.4 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:1990917 sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.4 1.6 GO:0016793 dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793) guanyl deoxyribonucleotide binding(GO:0032560) dGTP binding(GO:0032567)
0.3 0.8 GO:0033749 histone demethylase activity (H3-R2 specific)(GO:0033746) histone demethylase activity (H4-R3 specific)(GO:0033749)
0.2 2.0 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.2 0.5 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.4 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.4 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 0.4 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.5 GO:0070728 leucine binding(GO:0070728)
0.1 0.4 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 0.6 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.1 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
0.0 1.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.1 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 1.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0002135 CTP binding(GO:0002135)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.1 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0030911 nitric-oxide synthase regulator activity(GO:0030235) TPR domain binding(GO:0030911)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.2 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.5 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 1.0 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.5 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC