Inflammatory response time course, HUVEC (Wada, 2009)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
IKZF2 Links Ensembl NCBI GeneCards UniProt	ENSG00000030419.17	IKZF2

Gene	Promoter	Pearson corr. coef.	P-value	Plot
IKZF2	hg38_v1_chr2_-_213151590_213151619	-0.07	7.4e-01	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr1_+_100719734 Show fit	4.12	ENST00000370119.8 ENST00000294728.7 ENST00000347652.6 ENST00000370115.1	VCAM1 Links Ensembl NCBI GeneCards UniProt Show fit	vascular cell adhesion molecule 1
chr7_+_94394886 Show fit	2.10	ENST00000297268.11 ENST00000620463.1	COL1A2 Links Ensembl NCBI GeneCards UniProt Show fit	collagen type I alpha 2 chain
chr17_-_69141878 Show fit	2.08	ENST00000590645.1 ENST00000284425.7	ABCA6 Links Ensembl NCBI GeneCards UniProt Show fit	ATP binding cassette subfamily A member 6
chr8_+_96584920 Show fit	2.03	ENST00000521590.5	SDC2 Links Ensembl NCBI GeneCards UniProt Show fit	syndecan 2
chr6_-_142945028 Show fit	1.86	ENST00000012134.7	HIVEP2 Links Ensembl NCBI GeneCards UniProt Show fit	HIVEP zinc finger 2
chr6_-_142945160 Show fit	1.84	ENST00000367603.8	HIVEP2 Links Ensembl NCBI GeneCards UniProt Show fit	HIVEP zinc finger 2
chr8_-_6563044 Show fit	1.82	ENST00000338312.10	ANGPT2 Links Ensembl NCBI GeneCards UniProt Show fit	angiopoietin 2
chr17_+_28042839 Show fit	1.62	ENST00000582037.2	NLK Links Ensembl NCBI GeneCards UniProt Show fit	nemo like kinase
chr8_-_6563238 Show fit	1.62	ENST00000629816.3 ENST00000523120.2	ANGPT2 Links Ensembl NCBI GeneCards UniProt Show fit	angiopoietin 2
chr8_-_6563409 Show fit	1.58	ENST00000325203.9	ANGPT2 Links Ensembl NCBI GeneCards UniProt Show fit	angiopoietin 2
chr6_-_10412367 Show fit	1.55	ENST00000379608.9	TFAP2A Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor AP-2 alpha
chr6_+_106098933 Show fit	1.47	ENST00000369089.3	PRDM1 Links Ensembl NCBI GeneCards UniProt Show fit	PR/SET domain 1
chr1_-_173050931 Show fit	1.43	ENST00000404377.5	TNFSF18 Links Ensembl NCBI GeneCards UniProt Show fit	TNF superfamily member 18
chr12_+_26195647 Show fit	1.31	ENST00000535504.1	SSPN Links Ensembl NCBI GeneCards UniProt Show fit	sarcospan
chr10_+_113709261 Show fit	1.27	ENST00000672138.1 ENST00000452490.3	CASP7 Links Ensembl NCBI GeneCards UniProt Show fit	caspase 7
chr1_-_56579555 Show fit	1.24	ENST00000371250.4	PLPP3 Links Ensembl NCBI GeneCards UniProt Show fit	phospholipid phosphatase 3
chr2_+_102070360 Show fit	1.22	ENST00000409929.5 ENST00000424272.5	IL1R1 Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 1 receptor type 1
chr15_-_55249029 Show fit	1.20	ENST00000566877.5	RAB27A Links Ensembl NCBI GeneCards UniProt Show fit	RAB27A, member RAS oncogene family
chr6_+_106086316 Show fit	1.18	ENST00000369091.6 ENST00000369096.9	PRDM1 Links Ensembl NCBI GeneCards UniProt Show fit	PR/SET domain 1
chr14_+_63204859 Show fit	1.15	ENST00000555125.1	RHOJ Links Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member J
chr2_-_24328113 Show fit	1.13	ENST00000622089.4	ITSN2 Links Ensembl NCBI GeneCards UniProt Show fit	intersectin 2
chr10_-_114684612 Show fit	1.07	ENST00000533213.6 ENST00000369252.8	ABLIM1 Links Ensembl NCBI GeneCards UniProt Show fit	actin binding LIM protein 1
chr1_+_148748774 Show fit	1.02	ENST00000322209.5	NUDT4B Links Ensembl NCBI GeneCards UniProt Show fit	nudix hydrolase 4B
chr15_-_59372863 Show fit	1.01	ENST00000288235.9	MYO1E Links Ensembl NCBI GeneCards UniProt Show fit	myosin IE
chr17_+_41226648 Show fit	0.96	ENST00000377721.3	KRTAP9-2 Links Ensembl NCBI GeneCards UniProt Show fit	keratin associated protein 9-2
chr2_+_188974364 Show fit	0.95	ENST00000304636.9 ENST00000317840.9	COL3A1 Links Ensembl NCBI GeneCards UniProt Show fit	collagen type III alpha 1 chain
chr3_-_149333407 Show fit	0.93	ENST00000470080.5	TM4SF18 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane 4 L six family member 18
chr4_-_145938473 Show fit	0.91	ENST00000513320.5	ZNF827 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 827
chr12_-_104050112 Show fit	0.85	ENST00000547583.1 ENST00000546851.1 ENST00000360814.9	GLT8D2 Links Ensembl NCBI GeneCards UniProt Show fit	glycosyltransferase 8 domain containing 2
chr3_-_71583683 Show fit	0.84	ENST00000649631.1 ENST00000648718.1	FOXP1 Links Ensembl NCBI GeneCards UniProt Show fit	forkhead box P1
chr4_+_133149307 Show fit	0.83	ENST00000618019.1	PCDH10 Links Ensembl NCBI GeneCards UniProt Show fit	protocadherin 10
chr11_-_75306688 Show fit	0.82	ENST00000532525.1	ARRB1 Links Ensembl NCBI GeneCards UniProt Show fit	arrestin beta 1
chr7_+_30852273 Show fit	0.81	ENST00000509504.2	ENSG00000250424.4 Links Ensembl NCBI GeneCards UniProt Show fit	novel protein, MINDY4 and AQP1 readthrough
chr8_+_122781621 Show fit	0.75	ENST00000314393.6	ZHX2 Links Ensembl NCBI GeneCards UniProt Show fit	zinc fingers and homeoboxes 2
chr2_+_27078598 Show fit	0.75	ENST00000380320.9	EMILIN1 Links Ensembl NCBI GeneCards UniProt Show fit	elastin microfibril interfacer 1
chr15_-_82045998 Show fit	0.75	ENST00000329713.5	MEX3B Links Ensembl NCBI GeneCards UniProt Show fit	mex-3 RNA binding family member B
chr15_-_82046119 Show fit	0.74	ENST00000558133.1	MEX3B Links Ensembl NCBI GeneCards UniProt Show fit	mex-3 RNA binding family member B
chr3_-_71583592 Show fit	0.74	ENST00000650156.1 ENST00000649596.1	FOXP1 Links Ensembl NCBI GeneCards UniProt Show fit	forkhead box P1
chr3_-_112610262 Show fit	0.72	ENST00000479368.1	CCDC80 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 80
chr13_+_97222296 Show fit	0.70	ENST00000343600.8 ENST00000376673.7 ENST00000679496.1 ENST00000345429.10	MBNL2 Links Ensembl NCBI GeneCards UniProt Show fit	muscleblind like splicing regulator 2
chr15_+_73683938 Show fit	0.69	ENST00000567189.5	CD276 Links Ensembl NCBI GeneCards UniProt Show fit	CD276 molecule
chr4_-_145938422 Show fit	0.68	ENST00000656985.1 ENST00000652097.1 ENST00000503462.3 ENST00000379448.9 ENST00000513840.2	ZNF827 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 827
chr2_-_222320124 Show fit	0.66	ENST00000678139.1	ENSG00000288658.1 Links Ensembl NCBI GeneCards UniProt Show fit	novel protein, ortholog of Gm2102 (M. musculus)
chr14_+_63204436 Show fit	0.66	ENST00000316754.8	RHOJ Links Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member J
chrX_+_9543103 Show fit	0.66	ENST00000683056.1	TBL1X Links Ensembl NCBI GeneCards UniProt Show fit	transducin beta like 1 X-linked
chr14_+_22281097 Show fit	0.65	ENST00000390465.2	TRAV38-2DV8 Links Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha variable 38-2/delta variable 8
chr2_-_24360299 Show fit	0.64	ENST00000361999.7	ITSN2 Links Ensembl NCBI GeneCards UniProt Show fit	intersectin 2
chr14_+_32076939 Show fit	0.64	ENST00000556611.5 ENST00000539826.6	ARHGAP5 Links Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 5
chr17_-_676348 Show fit	0.63	ENST00000681510.1 ENST00000679680.1	VPS53 Links Ensembl NCBI GeneCards UniProt Show fit	VPS53 subunit of GARP complex
chr15_-_58014097 Show fit	0.62	ENST00000559517.5	ALDH1A2 Links Ensembl NCBI GeneCards UniProt Show fit	aldehyde dehydrogenase 1 family member A2
chr6_+_29395631 Show fit	0.61	ENST00000642051.1	OR12D2 Links Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 12 subfamily D member 2
chr22_-_45212431 Show fit	0.61	ENST00000496226.1 ENST00000251993.11	KIAA0930 Links Ensembl NCBI GeneCards UniProt Show fit	KIAA0930
chr2_-_159798043 Show fit	0.60	ENST00000664982.1 ENST00000259053.6	ENSG00000287091.1 Links Ensembl NCBI GeneCards UniProt Show fit CD302 Links Ensembl NCBI GeneCards UniProt Show fit	novel transcript, sense intronic to CD302and LY75-CD302 CD302 molecule
chr3_-_71583713 Show fit	0.60	ENST00000649528.3 ENST00000471386.3 ENST00000493089.7	FOXP1 Links Ensembl NCBI GeneCards UniProt Show fit	forkhead box P1
chr9_-_16705062 Show fit	0.60	ENST00000471301.3	BNC2 Links Ensembl NCBI GeneCards UniProt Show fit	basonuclin 2
chr18_-_55403682 Show fit	0.59	ENST00000564228.5 ENST00000630828.2	TCF4 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr9_+_89605004 Show fit	0.59	ENST00000252506.11 ENST00000375769.1	GADD45G Links Ensembl NCBI GeneCards UniProt Show fit	growth arrest and DNA damage inducible gamma
chr9_+_2159672 Show fit	0.59	ENST00000634343.1	SMARCA2 Links Ensembl NCBI GeneCards UniProt Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr19_+_11089446 Show fit	0.57	ENST00000557933.5 ENST00000455727.6 ENST00000535915.5 ENST00000545707.5 ENST00000558518.6 ENST00000558013.5	LDLR Links Ensembl NCBI GeneCards UniProt Show fit	low density lipoprotein receptor
chrX_+_136148440 Show fit	0.57	ENST00000627383.2 ENST00000630084.2	FHL1 Links Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr2_-_175005357 Show fit	0.57	ENST00000409156.7 ENST00000444573.2 ENST00000409900.9	CHN1 Links Ensembl NCBI GeneCards UniProt Show fit	chimerin 1
chr2_-_101151253 Show fit	0.57	ENST00000376840.8 ENST00000409318.2	TBC1D8 Links Ensembl NCBI GeneCards UniProt Show fit	TBC1 domain family member 8
chr16_-_20900319 Show fit	0.56	ENST00000564349.5 ENST00000324344.9	ERI2 Links Ensembl NCBI GeneCards UniProt Show fit DCUN1D3 Links Ensembl NCBI GeneCards UniProt Show fit	ERI1 exoribonuclease family member 2 defective in cullin neddylation 1 domain containing 3
chr17_-_40782544 Show fit	0.53	ENST00000301656.4	KRT27 Links Ensembl NCBI GeneCards UniProt Show fit	keratin 27
chr8_-_71356653 Show fit	0.53	ENST00000388742.8 ENST00000388740.4	EYA1 Links Ensembl NCBI GeneCards UniProt Show fit	EYA transcriptional coactivator and phosphatase 1
chr3_+_179148341 Show fit	0.53	ENST00000263967.4	PIK3CA Links Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
chr5_-_140633167 Show fit	0.53	ENST00000302014.11	CD14 Links Ensembl NCBI GeneCards UniProt Show fit	CD14 molecule
chr7_-_106284524 Show fit	0.52	ENST00000681936.1 ENST00000680786.1 ENST00000681550.1	NAMPT Links Ensembl NCBI GeneCards UniProt Show fit	nicotinamide phosphoribosyltransferase
chr1_-_150269051 Show fit	0.52	ENST00000414276.6 ENST00000360244.8	APH1A Links Ensembl NCBI GeneCards UniProt Show fit	aph-1 homolog A, gamma-secretase subunit
chr10_+_30434176 Show fit	0.51	ENST00000263056.6 ENST00000375322.2	MAP3K8 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase 8
chr12_+_121132869 Show fit	0.51	ENST00000328963.10	P2RX7 Links Ensembl NCBI GeneCards UniProt Show fit	purinergic receptor P2X 7
chr10_+_30434021 Show fit	0.50	ENST00000542547.5	MAP3K8 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase 8
chr6_+_27138588 Show fit	0.49	ENST00000615353.1	H4C9 Links Ensembl NCBI GeneCards UniProt Show fit	H4 clustered histone 9
chrX_+_28587411 Show fit	0.49	ENST00000378993.6	IL1RAPL1 Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 1 receptor accessory protein like 1
chr19_-_42765657 Show fit	0.49	ENST00000406636.7 ENST00000404209.8 ENST00000306511.5	PSG8 Links Ensembl NCBI GeneCards UniProt Show fit	pregnancy specific beta-1-glycoprotein 8
chr10_+_113125536 Show fit	0.48	ENST00000349937.7	TCF7L2 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor 7 like 2
chr9_+_2159850 Show fit	0.48	ENST00000416751.2	SMARCA2 Links Ensembl NCBI GeneCards UniProt Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr8_-_71356511 Show fit	0.48	ENST00000419131.6 ENST00000388743.6	EYA1 Links Ensembl NCBI GeneCards UniProt Show fit	EYA transcriptional coactivator and phosphatase 1
chr1_+_99646025 Show fit	0.47	ENST00000263174.9 ENST00000605497.5 ENST00000615664.1	PALMD Links Ensembl NCBI GeneCards UniProt Show fit	palmdelphin
chr20_-_10420737 Show fit	0.46	ENST00000649912.1	ENSG00000285723.1 Links Ensembl NCBI GeneCards UniProt Show fit	novel protein
chr1_-_155978524 Show fit	0.46	ENST00000361247.9	ARHGEF2 Links Ensembl NCBI GeneCards UniProt Show fit	Rho/Rac guanine nucleotide exchange factor 2
chr3_-_183099508 Show fit	0.46	ENST00000476176.5	MCCC1 Links Ensembl NCBI GeneCards UniProt Show fit	methylcrotonoyl-CoA carboxylase 1
chr11_-_33869816 Show fit	0.45	ENST00000395833.7	LMO2 Links Ensembl NCBI GeneCards UniProt Show fit	LIM domain only 2
chr19_-_57559833 Show fit	0.45	ENST00000457177.5	ZNF550 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 550
chr16_+_74999312 Show fit	0.44	ENST00000566250.5 ENST00000567962.5	ZNRF1 Links Ensembl NCBI GeneCards UniProt Show fit	zinc and ring finger 1
chr17_+_28042660 Show fit	0.44	ENST00000407008.8	NLK Links Ensembl NCBI GeneCards UniProt Show fit	nemo like kinase
chr12_-_123436664 Show fit	0.44	ENST00000280571.10	RILPL2 Links Ensembl NCBI GeneCards UniProt Show fit	Rab interacting lysosomal protein like 2
chr9_-_72365198 Show fit	0.44	ENST00000376962.10 ENST00000376960.8	ZFAND5 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger AN1-type containing 5
chr3_-_27722699 Show fit	0.43	ENST00000461503.2	EOMES Links Ensembl NCBI GeneCards UniProt Show fit	eomesodermin
chr17_+_7884783 Show fit	0.43	ENST00000380358.9	CHD3 Links Ensembl NCBI GeneCards UniProt Show fit	chromodomain helicase DNA binding protein 3
chrX_+_136169833 Show fit	0.43	ENST00000628032.2	FHL1 Links Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr12_-_91179472 Show fit	0.43	ENST00000550099.5 ENST00000546391.5	DCN Links Ensembl NCBI GeneCards UniProt Show fit	decorin
chr5_-_111756245 Show fit	0.42	ENST00000447165.6	NREP Links Ensembl NCBI GeneCards UniProt Show fit	neuronal regeneration related protein
chr17_-_17836973 Show fit	0.41	ENST00000261646.11 ENST00000355815.8	SREBF1 Links Ensembl NCBI GeneCards UniProt Show fit	sterol regulatory element binding transcription factor 1
chrX_+_136169624 Show fit	0.41	ENST00000394153.6	FHL1 Links Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr12_-_55927756 Show fit	0.41	ENST00000549939.1	PYM1 Links Ensembl NCBI GeneCards UniProt Show fit	PYM homolog 1, exon junction complex associated factor
chr4_+_133149278 Show fit	0.41	ENST00000264360.7	PCDH10 Links Ensembl NCBI GeneCards UniProt Show fit	protocadherin 10
chr5_-_176388563 Show fit	0.40	ENST00000509257.1 ENST00000616685.1 ENST00000614830.5	NOP16 Links Ensembl NCBI GeneCards UniProt Show fit	NOP16 nucleolar protein
chr13_-_40982880 Show fit	0.40	ENST00000635415.1	ELF1 Links Ensembl NCBI GeneCards UniProt Show fit	E74 like ETS transcription factor 1
chr12_-_71157872 Show fit	0.40	ENST00000546561.2	TSPAN8 Links Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 8
chrX_-_136780925 Show fit	0.40	ENST00000250617.7	ARHGEF6 Links Ensembl NCBI GeneCards UniProt Show fit	Rac/Cdc42 guanine nucleotide exchange factor 6
chr16_+_74999003 Show fit	0.40	ENST00000335325.9 ENST00000320619.10	ZNRF1 Links Ensembl NCBI GeneCards UniProt Show fit	zinc and ring finger 1
chr1_-_155978427 Show fit	0.40	ENST00000313667.8	ARHGEF2 Links Ensembl NCBI GeneCards UniProt Show fit	Rho/Rac guanine nucleotide exchange factor 2
chrX_+_136169664 Show fit	0.39	ENST00000456445.5	FHL1 Links Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr12_-_71157992 Show fit	0.39	ENST00000247829.8	TSPAN8 Links Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 8
chr4_+_168832005 Show fit	0.39	ENST00000393726.7 ENST00000507735.6	PALLD Links Ensembl NCBI GeneCards UniProt Show fit	palladin, cytoskeletal associated protein
chr5_-_176388629 Show fit	0.39	ENST00000619979.4 ENST00000621444.4	NOP16 Links Ensembl NCBI GeneCards UniProt Show fit	NOP16 nucleolar protein
chr9_-_70869076 Show fit	0.39	ENST00000677594.1	TRPM3 Links Ensembl NCBI GeneCards UniProt Show fit	transient receptor potential cation channel subfamily M member 3
chr18_+_58196736 Show fit	0.39	ENST00000675221.1	NEDD4L Links Ensembl NCBI GeneCards UniProt Show fit	NEDD4 like E3 ubiquitin protein ligase
chr3_+_160842143 Show fit	0.38	ENST00000464260.5 ENST00000295839.9	PPM1L Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase, Mg2+/Mn2+ dependent 1L
chr11_-_86068743 Show fit	0.38	ENST00000356360.9	PICALM Links Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol binding clathrin assembly protein
chr18_-_57586668 Show fit	0.38	ENST00000592699.6 ENST00000382873.8 ENST00000262093.11 ENST00000652755.1	FECH Links Ensembl NCBI GeneCards UniProt Show fit	ferrochelatase
chr9_+_34989641 Show fit	0.38	ENST00000453597.8 ENST00000312316.9 ENST00000458263.6 ENST00000537321.5 ENST00000682809.1 ENST00000684748.1	DNAJB5 Links Ensembl NCBI GeneCards UniProt Show fit	DnaJ heat shock protein family (Hsp40) member B5
chr14_-_44961889 Show fit	0.38	ENST00000579157.1 ENST00000396128.9 ENST00000556500.1	KLHL28 Links Ensembl NCBI GeneCards UniProt Show fit	kelch like family member 28
chr18_-_55422306 Show fit	0.37	ENST00000566777.5 ENST00000626584.2	TCF4 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr5_+_154038953 Show fit	0.37	ENST00000439768.2 ENST00000522782.6 ENST00000322602.9 ENST00000522177.1 ENST00000520899.1	MFAP3 Links Ensembl NCBI GeneCards UniProt Show fit	microfibril associated protein 3
chr22_-_35824373 Show fit	0.36	ENST00000473487.6	RBFOX2 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding fox-1 homolog 2
chr6_+_31655888 Show fit	0.36	ENST00000375916.4	APOM Links Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein M
chr7_-_93219564 Show fit	0.36	ENST00000341723.8	HEPACAM2 Links Ensembl NCBI GeneCards UniProt Show fit	HEPACAM family member 2
chr7_-_93219545 Show fit	0.36	ENST00000440868.5	HEPACAM2 Links Ensembl NCBI GeneCards UniProt Show fit	HEPACAM family member 2
chr17_+_41249687 Show fit	0.35	ENST00000334109.3	KRTAP9-4 Links Ensembl NCBI GeneCards UniProt Show fit	keratin associated protein 9-4
chr12_+_59664677 Show fit	0.35	ENST00000548610.5	SLC16A7 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 16 member 7
chr9_+_5510492 Show fit	0.35	ENST00000397747.5	PDCD1LG2 Links Ensembl NCBI GeneCards UniProt Show fit	programmed cell death 1 ligand 2
chr14_-_106235582 Show fit	0.35	ENST00000390607.2	IGHV3-21 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-21
chr7_+_1086800 Show fit	0.34	ENST00000413368.5 ENST00000397092.5 ENST00000297469.3	GPER1 Links Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled estrogen receptor 1
chr17_+_34285734 Show fit	0.34	ENST00000305869.4	CCL11 Links Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine ligand 11
chr20_+_38805686 Show fit	0.34	ENST00000299824.6 ENST00000373331.2	PPP1R16B Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory subunit 16B
chr3_+_41194741 Show fit	0.33	ENST00000643541.1 ENST00000426215.5 ENST00000645210.1 ENST00000646381.1 ENST00000405570.6 ENST00000642248.1 ENST00000433400.6	CTNNB1 Links Ensembl NCBI GeneCards UniProt Show fit	catenin beta 1
chrX_+_81202066 Show fit	0.33	ENST00000373212.6	SH3BGRL Links Ensembl NCBI GeneCards UniProt Show fit	SH3 domain binding glutamate rich protein like
chrX_-_101407893 Show fit	0.33	ENST00000676156.1 ENST00000675592.1 ENST00000674634.2 ENST00000649178.1 ENST00000218516.4	GLA Links Ensembl NCBI GeneCards UniProt Show fit	galactosidase alpha
chr6_+_87344812 Show fit	0.33	ENST00000388923.5	C6orf163 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 6 open reading frame 163
chr2_-_127675459 Show fit	0.33	ENST00000355119.9	LIMS2 Links Ensembl NCBI GeneCards UniProt Show fit	LIM zinc finger domain containing 2
chr2_-_55334529 Show fit	0.33	ENST00000645860.1 ENST00000642563.1 ENST00000647396.1	CCDC88A Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 88A
chrX_+_41339931 Show fit	0.32	ENST00000642424.1	DDX3X Links Ensembl NCBI GeneCards UniProt Show fit	DEAD-box helicase 3 X-linked
chr18_-_55422492 Show fit	0.32	ENST00000561992.5 ENST00000630712.2	TCF4 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr15_+_40439721 Show fit	0.31	ENST00000561234.5	BAHD1 Links Ensembl NCBI GeneCards UniProt Show fit	bromo adjacent homology domain containing 1
chr17_-_7217206 Show fit	0.31	ENST00000447163.6 ENST00000647975.1	DLG4 Links Ensembl NCBI GeneCards UniProt Show fit	discs large MAGUK scaffold protein 4
chr2_-_127675065 Show fit	0.31	ENST00000545738.6 ENST00000409808.6	LIMS2 Links Ensembl NCBI GeneCards UniProt Show fit	LIM zinc finger domain containing 2
chr11_-_55936400 Show fit	0.31	ENST00000301532.3	OR5I1 Links Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 5 subfamily I member 1
chr5_+_173889337 Show fit	0.31	ENST00000520867.5 ENST00000334035.9	CPEB4 Links Ensembl NCBI GeneCards UniProt Show fit	cytoplasmic polyadenylation element binding protein 4
chr2_-_208255055 Show fit	0.31	ENST00000345146.7	IDH1 Links Ensembl NCBI GeneCards UniProt Show fit	isocitrate dehydrogenase (NADP(+)) 1
chr20_-_44504850 Show fit	0.30	ENST00000411544.5	SERINC3 Links Ensembl NCBI GeneCards UniProt Show fit	serine incorporator 3
chr10_+_110919595 Show fit	0.29	ENST00000369452.9	SHOC2 Links Ensembl NCBI GeneCards UniProt Show fit	SHOC2 leucine rich repeat scaffold protein
chrX_-_41665766 Show fit	0.29	ENST00000643043.2 ENST00000486402.1 ENST00000646087.2	CASK Links Ensembl NCBI GeneCards UniProt Show fit	calcium/calmodulin dependent serine protein kinase
chr10_-_92497727 Show fit	0.29	ENST00000496903.5 ENST00000678824.1 ENST00000371581.9	IDE Links Ensembl NCBI GeneCards UniProt Show fit	insulin degrading enzyme
chr2_-_227379297 Show fit	0.28	ENST00000304568.4	TM4SF20 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane 4 L six family member 20
chr12_-_55927865 Show fit	0.27	ENST00000454792.2 ENST00000408946.7	PYM1 Links Ensembl NCBI GeneCards UniProt Show fit	PYM homolog 1, exon junction complex associated factor
chr1_+_50105666 Show fit	0.27	ENST00000651347.1	ELAVL4 Links Ensembl NCBI GeneCards UniProt Show fit	ELAV like RNA binding protein 4
chr17_-_41041447 Show fit	0.26	ENST00000306271.5	KRTAP1-1 Links Ensembl NCBI GeneCards UniProt Show fit	keratin associated protein 1-1
chrX_+_136648214 Show fit	0.26	ENST00000370628.2	CD40LG Links Ensembl NCBI GeneCards UniProt Show fit	CD40 ligand
chr11_-_72785932 Show fit	0.26	ENST00000539138.1 ENST00000542989.5	STARD10 Links Ensembl NCBI GeneCards UniProt Show fit	StAR related lipid transfer domain containing 10
chr15_+_73684204 Show fit	0.26	ENST00000537340.6 ENST00000318424.9	CD276 Links Ensembl NCBI GeneCards UniProt Show fit	CD276 molecule
chrX_+_136648138 Show fit	0.26	ENST00000370629.7	CD40LG Links Ensembl NCBI GeneCards UniProt Show fit	CD40 ligand
chr13_-_46182136 Show fit	0.26	ENST00000323076.7	LCP1 Links Ensembl NCBI GeneCards UniProt Show fit	lymphocyte cytosolic protein 1
chr6_-_131063207 Show fit	0.26	ENST00000530481.5	EPB41L2 Links Ensembl NCBI GeneCards UniProt Show fit	erythrocyte membrane protein band 4.1 like 2
chr11_-_65662780 Show fit	0.26	ENST00000534283.1 ENST00000527749.5 ENST00000533187.5 ENST00000525693.5 ENST00000534558.5 ENST00000532879.5 ENST00000406246.8 ENST00000532999.5	RELA Links Ensembl NCBI GeneCards UniProt Show fit	RELA proto-oncogene, NF-kB subunit
chr1_+_171248471 Show fit	0.25	ENST00000402921.6 ENST00000617670.6 ENST00000367750.7	FMO1 Links Ensembl NCBI GeneCards UniProt Show fit	flavin containing dimethylaniline monoxygenase 1
chr15_+_81000913 Show fit	0.25	ENST00000267984.4	TLNRD1 Links Ensembl NCBI GeneCards UniProt Show fit	talin rod domain containing 1
chrX_+_103776493 Show fit	0.25	ENST00000433491.5 ENST00000612423.4 ENST00000443502.5	PLP1 Links Ensembl NCBI GeneCards UniProt Show fit	proteolipid protein 1
chr19_+_30372364 Show fit	0.25	ENST00000355537.4	ZNF536 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 536
chr19_-_54941610 Show fit	0.24	ENST00000328092.9 ENST00000590030.5	NLRP7 Links Ensembl NCBI GeneCards UniProt Show fit	NLR family pyrin domain containing 7
chr1_-_17045219 Show fit	0.24	ENST00000491274.5	SDHB Links Ensembl NCBI GeneCards UniProt Show fit	succinate dehydrogenase complex iron sulfur subunit B
chr2_-_196926670 Show fit	0.24	ENST00000354764.9	PGAP1 Links Ensembl NCBI GeneCards UniProt Show fit	post-GPI attachment to proteins inositol deacylase 1
chr6_+_108166015 Show fit	0.24	ENST00000368986.9	NR2E1 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 2 group E member 1
chrX_+_103776831 Show fit	0.24	ENST00000621218.5 ENST00000619236.1	PLP1 Links Ensembl NCBI GeneCards UniProt Show fit	proteolipid protein 1
chr19_+_43716095 Show fit	0.24	ENST00000596627.1	IRGC Links Ensembl NCBI GeneCards UniProt Show fit	immunity related GTPase cinema
chr6_+_31670167 Show fit	0.24	ENST00000375864.4	LY6G5B Links Ensembl NCBI GeneCards UniProt Show fit	lymphocyte antigen 6 family member G5B
chr17_+_7888783 Show fit	0.23	ENST00000330494.12 ENST00000358181.8	CHD3 Links Ensembl NCBI GeneCards UniProt Show fit	chromodomain helicase DNA binding protein 3
chrX_+_101550537 Show fit	0.23	ENST00000372829.8	ARMCX1 Links Ensembl NCBI GeneCards UniProt Show fit	armadillo repeat containing X-linked 1
chr1_+_174964750 Show fit	0.23	ENST00000367688.3	RABGAP1L Links Ensembl NCBI GeneCards UniProt Show fit	RAB GTPase activating protein 1 like
chr22_+_39901075 Show fit	0.23	ENST00000344138.9	GRAP2 Links Ensembl NCBI GeneCards UniProt Show fit	GRB2 related adaptor protein 2
chr4_-_167234266 Show fit	0.23	ENST00000511269.5 ENST00000506697.5 ENST00000512042.1	SPOCK3 Links Ensembl NCBI GeneCards UniProt Show fit	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr19_-_43205551 Show fit	0.23	ENST00000599391.1 ENST00000244295.13 ENST00000596907.5 ENST00000405312.8 ENST00000451895.1 ENST00000433626.6	PSG4 Links Ensembl NCBI GeneCards UniProt Show fit	pregnancy specific beta-1-glycoprotein 4
chr20_+_58891302 Show fit	0.23	ENST00000371095.7 ENST00000265620.11 ENST00000354359.12 ENST00000371085.8	GNAS Links Ensembl NCBI GeneCards UniProt Show fit	GNAS complex locus
chr6_-_131063272 Show fit	0.23	ENST00000445890.6 ENST00000368128.6 ENST00000628542.2	EPB41L2 Links Ensembl NCBI GeneCards UniProt Show fit	erythrocyte membrane protein band 4.1 like 2
chr18_-_55321640 Show fit	0.23	ENST00000637169.2	TCF4 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr20_+_45881218 Show fit	0.23	ENST00000372523.1	ZSWIM1 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger SWIM-type containing 1
chr8_-_140921188 Show fit	0.23	ENST00000517887.5	PTK2 Links Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine kinase 2
chr2_+_233032672 Show fit	0.22	ENST00000233840.3	NEU2 Links Ensembl NCBI GeneCards UniProt Show fit	neuraminidase 2
chr6_+_32976347 Show fit	0.22	ENST00000606059.1	BRD2 Links Ensembl NCBI GeneCards UniProt Show fit	bromodomain containing 2
chr7_+_134986483 Show fit	0.22	ENST00000436302.6 ENST00000435976.6 ENST00000455283.2	AGBL3 Links Ensembl NCBI GeneCards UniProt Show fit	ATP/GTP binding protein like 3
chr12_+_122021850 Show fit	0.22	ENST00000261822.5	BCL7A Links Ensembl NCBI GeneCards UniProt Show fit	BAF chromatin remodeling complex subunit BCL7A
chr6_-_131063233 Show fit	0.21	ENST00000392427.7 ENST00000337057.8 ENST00000525271.5 ENST00000527411.5	EPB41L2 Links Ensembl NCBI GeneCards UniProt Show fit	erythrocyte membrane protein band 4.1 like 2
chr19_-_12666695 Show fit	0.21	ENST00000221363.8 ENST00000598876.1 ENST00000456935.7 ENST00000486847.2	MAN2B1 Links Ensembl NCBI GeneCards UniProt Show fit	mannosidase alpha class 2B member 1
chr1_-_159714581 Show fit	0.21	ENST00000255030.9 ENST00000437342.1 ENST00000368112.5 ENST00000368111.5 ENST00000368110.1	CRP Links Ensembl NCBI GeneCards UniProt Show fit	C-reactive protein
chr12_-_86838867 Show fit	0.21	ENST00000621808.4	MGAT4C Links Ensembl NCBI GeneCards UniProt Show fit	MGAT4 family member C
chr11_-_65662931 Show fit	0.21	ENST00000615805.4 ENST00000612991.4	RELA Links Ensembl NCBI GeneCards UniProt Show fit	RELA proto-oncogene, NF-kB subunit
chr3_+_46577778 Show fit	0.21	ENST00000296145.6	TDGF1 Links Ensembl NCBI GeneCards UniProt Show fit	teratocarcinoma-derived growth factor 1
chr1_+_161749762 Show fit	0.21	ENST00000367943.5	DUSP12 Links Ensembl NCBI GeneCards UniProt Show fit	dual specificity phosphatase 12
chr17_-_7217178 Show fit	0.20	ENST00000485100.5	DLG4 Links Ensembl NCBI GeneCards UniProt Show fit	discs large MAGUK scaffold protein 4
chr15_+_84603896 Show fit	0.20	ENST00000541040.5 ENST00000538076.5 ENST00000485222.2	ZSCAN2 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger and SCAN domain containing 2
chr1_+_158831323 Show fit	0.20	ENST00000368141.5	MNDA Links Ensembl NCBI GeneCards UniProt Show fit	myeloid cell nuclear differentiation antigen
chr1_-_34165219 Show fit	0.20	ENST00000373381.9	CSMD2 Links Ensembl NCBI GeneCards UniProt Show fit	CUB and Sushi multiple domains 2
chr13_-_72781871 Show fit	0.20	ENST00000377767.9 ENST00000377780.8	DIS3 Links Ensembl NCBI GeneCards UniProt Show fit	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease
chr6_-_26056460 Show fit	0.20	ENST00000343677.4	H1-2 Links Ensembl NCBI GeneCards UniProt Show fit	H1.2 linker histone, cluster member
chr1_-_68232514 Show fit	0.19	ENST00000262348.9 ENST00000370973.2 ENST00000370971.1	WLS Links Ensembl NCBI GeneCards UniProt Show fit	Wnt ligand secretion mediator
chr1_+_209768597 Show fit	0.19	ENST00000487271.5 ENST00000477431.1	TRAF3IP3 Links Ensembl NCBI GeneCards UniProt Show fit	TRAF3 interacting protein 3
chr9_-_127905313 Show fit	0.19	ENST00000622357.5	ST6GALNAC6 Links Ensembl NCBI GeneCards UniProt Show fit	ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr7_+_55365317 Show fit	0.19	ENST00000254770.3	LANCL2 Links Ensembl NCBI GeneCards UniProt Show fit	LanC like 2
chr5_-_16508990 Show fit	0.19	ENST00000399793.6	RETREG1 Links Ensembl NCBI GeneCards UniProt Show fit	reticulophagy regulator 1

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	5.0	GO:0050928	negative regulation of positive chemotaxis(GO:0050928)
0.9	2.6	GO:0033082	regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.6	4.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.4	1.2	GO:2000661	positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.4	1.6	GO:0003409	optic cup structural organization(GO:0003409)
0.4	1.4	GO:2000329	negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.3	2.0	GO:0008218	bioluminescence(GO:0008218)
0.2	0.7	GO:1903259	exon-exon junction complex disassembly(GO:1903259)
0.2	1.2	GO:1903435	positive regulation of constitutive secretory pathway(GO:1903435)
0.2	0.9	GO:0071802	negative regulation of podosome assembly(GO:0071802)
0.2	0.5	GO:1904172	positive regulation of interleukin-1 alpha secretion(GO:0050717) regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172)
0.2	1.3	GO:0072733	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.2	0.5	GO:0006117	acetaldehyde metabolic process(GO:0006117)
0.1	0.7	GO:1903978	regulation of microglial cell activation(GO:1903978)
0.1	0.4	GO:0002302	CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.1	2.1	GO:0043589	skin morphogenesis(GO:0043589)
0.1	0.9	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1	2.2	GO:0032625	interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1	1.0	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
0.1	1.8	GO:0061299	retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1	0.3	GO:0031959	mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.1	0.3	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1	1.0	GO:0072513	positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1	0.4	GO:0046909	intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1	0.5	GO:2000653	regulation of genetic imprinting(GO:2000653)
0.1	0.5	GO:0038123	toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1	1.4	GO:0008354	germ cell migration(GO:0008354)
0.1	0.3	GO:0006097	glyoxylate cycle(GO:0006097)
0.1	0.8	GO:0042699	follicle-stimulating hormone signaling pathway(GO:0042699)
0.1	0.4	GO:0034444	regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.1	0.4	GO:0061357	positive regulation of Wnt protein secretion(GO:0061357)
0.1	0.2	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.1	0.3	GO:1901143	insulin catabolic process(GO:1901143)
0.1	0.6	GO:0042904	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1	0.3	GO:0035962	response to interleukin-13(GO:0035962)
0.1	2.1	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.1	0.2	GO:1901421	positive regulation of response to alcohol(GO:1901421)
0.1	0.8	GO:0044334	canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.1	0.2	GO:2000174	regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.1	1.0	GO:0045078	positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1	0.4	GO:1902963	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1	0.3	GO:1903566	positive regulation of protein localization to cilium(GO:1903566)
0.0	0.6	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.0	0.3	GO:0016139	glycoside catabolic process(GO:0016139)
0.0	0.2	GO:0018008	N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.0	0.4	GO:0006848	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0	0.4	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.0	0.3	GO:0009597	detection of virus(GO:0009597)
0.0	1.9	GO:1903861	positive regulation of dendrite extension(GO:1903861)
0.0	0.1	GO:1903015	regulation of exo-alpha-sialidase activity(GO:1903015)
0.0	0.2	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.2	GO:0035610	protein side chain deglutamylation(GO:0035610)
0.0	0.5	GO:0097113	AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0	0.9	GO:0042789	mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0	0.4	GO:0006552	leucine catabolic process(GO:0006552)
0.0	0.3	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0	0.2	GO:0033133	positive regulation of glucokinase activity(GO:0033133)
0.0	0.3	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.0	0.1	GO:0036269	swimming behavior(GO:0036269)
0.0	0.6	GO:0010225	response to UV-C(GO:0010225)
0.0	0.3	GO:0070995	NADPH oxidation(GO:0070995)
0.0	0.1	GO:0070845	misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0	0.2	GO:0033591	response to L-ascorbic acid(GO:0033591)
0.0	0.5	GO:0007220	Notch receptor processing(GO:0007220)
0.0	0.1	GO:1903926	signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0	0.1	GO:0021965	spinal cord ventral commissure morphogenesis(GO:0021965)
0.0	0.1	GO:0099558	maintenance of synapse structure(GO:0099558)
0.0	0.2	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.1	GO:0044855	plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0	0.2	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.6	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.4	GO:0017085	response to insecticide(GO:0017085)
0.0	0.2	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.0	0.6	GO:1900745	positive regulation of p38MAPK cascade(GO:1900745)
0.0	0.2	GO:0090666	scaRNA localization to Cajal body(GO:0090666)
0.0	0.5	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.0	0.5	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0	0.5	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0	0.2	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.0	GO:1902725	negative regulation of satellite cell differentiation(GO:1902725)
0.0	0.1	GO:1904381	Golgi apparatus mannose trimming(GO:1904381)
0.0	0.1	GO:0045410	positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.0	0.3	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.3	GO:1900364	negative regulation of mRNA polyadenylation(GO:1900364)
0.0	0.1	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0	0.1	GO:0090427	activation of meiosis(GO:0090427)
0.0	0.3	GO:0032782	bile acid secretion(GO:0032782)
0.0	0.2	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.0	0.4	GO:0003334	keratinocyte development(GO:0003334)
0.0	0.1	GO:0035910	ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.0	0.5	GO:0031069	hair follicle morphogenesis(GO:0031069)
0.0	0.0	GO:0040030	regulation of molecular function, epigenetic(GO:0040030)
0.0	1.6	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.3	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.1	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0	0.2	GO:0019375	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0	0.1	GO:0010716	negative regulation of extracellular matrix disassembly(GO:0010716)
0.0	0.6	GO:0003416	endochondral bone growth(GO:0003416)
0.0	0.1	GO:0015798	myo-inositol transport(GO:0015798)
0.0	0.0	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.0	0.1	GO:2000435	regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0	0.2	GO:0001887	selenium compound metabolic process(GO:0001887)
0.0	0.0	GO:0010607	negative regulation of cytoplasmic mRNA processing body assembly(GO:0010607)
0.0	0.1	GO:0070858	negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0	0.2	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.0	0.4	GO:0050860	negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.2	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.3	GO:0048745	smooth muscle tissue development(GO:0048745)
0.0	0.8	GO:0070207	protein homotrimerization(GO:0070207)
0.0	0.1	GO:0060440	trachea formation(GO:0060440)
0.0	0.6	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.2	GO:0040032	post-embryonic body morphogenesis(GO:0040032)
0.0	0.1	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.3	GO:0031507	heterochromatin assembly(GO:0031507)
0.0	0.2	GO:0032930	positive regulation of superoxide anion generation(GO:0032930)
0.0	0.2	GO:0006105	succinate metabolic process(GO:0006105)
0.0	0.2	GO:0038007	netrin-activated signaling pathway(GO:0038007) negative regulation of synapse assembly(GO:0051964)
0.0	0.1	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.1	GO:0010751	regulation of nitric oxide mediated signal transduction(GO:0010749) negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.0	1.0	GO:0000186	activation of MAPKK activity(GO:0000186)
0.0	0.4	GO:0016048	detection of temperature stimulus(GO:0016048)
0.0	0.2	GO:0006677	glycosylceramide metabolic process(GO:0006677)
0.0	0.2	GO:0035641	locomotory exploration behavior(GO:0035641)
0.0	1.4	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.2	GO:0007351	blastoderm segmentation(GO:0007350) tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0	0.0	GO:0070221	sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0	0.3	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.2	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.0	0.2	GO:0032310	prostaglandin secretion(GO:0032310)
0.0	0.2	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.0	GO:0010979	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) vitamin D catabolic process(GO:0042369)
0.0	0.2	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.0	GO:1903031	regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	4.1	GO:0071065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.2	2.8	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2	0.6	GO:1990666	PCSK9-LDLR complex(GO:1990666)
0.2	0.5	GO:0035525	NF-kappaB p50/p65 complex(GO:0035525)
0.1	0.5	GO:0005943	phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1	0.4	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
0.1	0.3	GO:0098843	postsynaptic endocytic zone(GO:0098843)
0.1	1.2	GO:0033093	Weibel-Palade body(GO:0033093)
0.1	0.4	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.1	0.8	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369)
0.1	0.5	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	0.5	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.4	GO:0002169	3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0	0.2	GO:0005749	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.2	GO:0071149	TEAD-2-YAP complex(GO:0071149)
0.0	0.7	GO:0008091	spectrin(GO:0008091)
0.0	0.3	GO:1990745	EARP complex(GO:1990745)
0.0	0.3	GO:0044327	dendritic spine head(GO:0044327)
0.0	0.5	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.5	GO:0098839	postsynaptic density membrane(GO:0098839)
0.0	0.5	GO:0032059	bleb(GO:0032059)
0.0	1.1	GO:0071564	npBAF complex(GO:0071564)
0.0	0.8	GO:0031143	pseudopodium(GO:0031143)
0.0	0.4	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	1.6	GO:0002102	podosome(GO:0002102)
0.0	0.4	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.3	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0	0.1	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.0	0.6	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.7	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.7	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0	2.7	GO:0043202	lysosomal lumen(GO:0043202)
0.0	1.5	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.3	GO:0031597	cytosolic proteasome complex(GO:0031597)
0.0	0.2	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.3	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.2	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.0	0.3	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.1	GO:0061689	tricellular tight junction(GO:0061689)
0.0	2.2	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.4	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	1.1	GO:0016459	myosin complex(GO:0016459)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	4.1	GO:0008131	primary amine oxidase activity(GO:0008131)
0.3	1.2	GO:0004909	interleukin-1, Type I, activating receptor activity(GO:0004909)
0.3	0.8	GO:0031896	V2 vasopressin receptor binding(GO:0031896)
0.3	0.8	GO:0098640	integrin binding involved in cell-matrix adhesion(GO:0098640)
0.2	3.0	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.2	1.2	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.2	0.5	GO:0005174	CD40 receptor binding(GO:0005174)
0.1	0.4	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1	0.5	GO:0047280	nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.1	0.3	GO:0051990	isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.1	0.3	GO:0031626	beta-endorphin binding(GO:0031626)
0.1	0.5	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.1	0.4	GO:0032810	sterol response element binding(GO:0032810)
0.1	0.3	GO:0043273	CTPase activity(GO:0043273)
0.1	0.6	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1	1.5	GO:0001087	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1	0.3	GO:0031728	CCR3 chemokine receptor binding(GO:0031728)
0.1	0.3	GO:0016936	galactoside binding(GO:0016936)
0.1	0.5	GO:0031812	G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1	0.7	GO:0042731	PH domain binding(GO:0042731)
0.1	2.0	GO:0004707	MAP kinase activity(GO:0004707)
0.1	0.2	GO:0051538	succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1	2.6	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.1	0.5	GO:0071532	ankyrin repeat binding(GO:0071532)
0.1	0.2	GO:0033265	choline binding(GO:0033265)
0.1	0.6	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.4	GO:0004485	methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0	5.1	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.0	0.5	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.2	GO:0052795	exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0	0.2	GO:0019107	glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.0	0.1	GO:0033754	indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0	1.2	GO:0031489	myosin V binding(GO:0031489)
0.0	0.1	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
0.0	0.3	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.1	GO:0070506	high-density lipoprotein particle receptor activity(GO:0070506)
0.0	0.3	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.2	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.0	0.2	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.5	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.4	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.0	0.9	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.3	GO:1990239	steroid hormone binding(GO:1990239)
0.0	2.4	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.2	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.0	1.0	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	2.8	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.3	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.0	0.6	GO:0097602	cullin family protein binding(GO:0097602)
0.0	1.0	GO:0000146	microfilament motor activity(GO:0000146)
0.0	0.9	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0	0.6	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.0	0.2	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0	1.5	GO:0032813	tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0	0.3	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.3	GO:0004559	alpha-mannosidase activity(GO:0004559)
0.0	1.0	GO:0042169	SH2 domain binding(GO:0042169)
0.0	1.3	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.1	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.0	0.1	GO:0010348	lithium:proton antiporter activity(GO:0010348)
0.0	0.8	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.0	0.1	GO:0042903	tubulin deacetylase activity(GO:0042903)
0.0	0.7	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.4	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.5	GO:0098811	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0	0.4	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	2.0	GO:0030165	PDZ domain binding(GO:0030165)
0.0	0.2	GO:0050694	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.1	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.0	0.1	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.4	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.2	GO:0008430	selenium binding(GO:0008430)
0.0	0.7	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.2	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.4	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	1.0	GO:0043022	ribosome binding(GO:0043022)
0.0	0.3	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.0	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.0	0.5	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0	1.1	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0	0.3	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.3	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	1.4	GO:0042626	ATPase activity, coupled to transmembrane movement of substances(GO:0042626)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.1	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	6.1	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.1	1.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	2.6	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.1	2.4	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	1.3	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	2.3	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	1.4	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	1.2	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.5	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.9	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.6	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.5	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	1.1	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	1.4	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.6	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.2	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.5	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	2.6	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	1.0	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.8	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.7	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.5	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.1	ST G ALPHA S PATHWAY	G alpha s Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.5	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	2.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	2.1	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.1	1.0	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.1	0.5	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.1	2.3	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	1.4	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	4.7	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	1.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	1.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	2.3	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.8	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.6	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	1.1	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.5	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	1.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.0	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.4	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	1.4	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.2	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.4	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.2	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.7	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.2	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules