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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for IRX2

Z-value: 0.55

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Transcription factors associated with IRX2

Gene Symbol Gene ID Gene Info
IRX2
ENSG00000170561.13 IRX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRX2hg38_v1_chr5_-_2751670_2751694-0.281.8e-01Click!

Activity profile of IRX2 motif

Sorted Z-values of IRX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr9_+_76459152 1.74 ENST00000444201.6
ENST00000376730.5
GCNT1
glucosaminyl (N-acetyl) transferase 1
chr7_+_150514851 1.17 ENST00000313543.5
GIMAP7
GTPase, IMAP family member 7
chr17_-_3691887 0.90 ENST00000552050.5
P2RX5
purinergic receptor P2X 5
chr13_+_102656933 0.87 ENST00000650757.1
TPP2
tripeptidyl peptidase 2
chr18_-_55403682 0.79 ENST00000564228.5
ENST00000630828.2
TCF4
transcription factor 4
chr9_-_137302264 0.78 ENST00000356628.4
NRARP
NOTCH regulated ankyrin repeat protein
chr7_+_107044689 0.64 ENST00000265717.5
PRKAR2B
protein kinase cAMP-dependent type II regulatory subunit beta
chr17_-_27800524 0.57 ENST00000313735.11
NOS2
nitric oxide synthase 2
chr8_-_85341659 0.57 ENST00000522389.5
CA1
carbonic anhydrase 1
chr9_-_35812238 0.56 ENST00000396638.7
ENST00000340291.6
SPAG8
sperm associated antigen 8
chr7_-_21945866 0.55 ENST00000356195.9
ENST00000447180.5
ENST00000373934.4
ENST00000406877.8
ENST00000457951.5
CDCA7L
cell division cycle associated 7 like
chr5_-_88731827 0.53 ENST00000627170.2
MEF2C
myocyte enhancer factor 2C
chr12_+_8992029 0.51 ENST00000543895.1
KLRG1
killer cell lectin like receptor G1
chr12_+_109098118 0.49 ENST00000336865.6
UNG
uracil DNA glycosylase
chr2_-_163735989 0.48 ENST00000333129.4
ENST00000409634.5
FIGN
fidgetin, microtubule severing factor
chr12_+_32502114 0.46 ENST00000682739.1
ENST00000427716.7
ENST00000583694.2
FGD4
FYVE, RhoGEF and PH domain containing 4
chr1_+_74235377 0.43 ENST00000326637.8
TNNI3K
TNNI3 interacting kinase
chr15_-_19988117 0.43 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr2_+_137964446 0.40 ENST00000280096.5
ENST00000280097.5
HNMT
histamine N-methyltransferase
chr2_+_190927649 0.38 ENST00000409428.5
ENST00000409215.5
GLS
glutaminase
chr6_+_24774925 0.38 ENST00000356509.7
ENST00000230056.8
GMNN
geminin DNA replication inhibitor
chr6_-_159045010 0.36 ENST00000338313.5
TAGAP
T cell activation RhoGTPase activating protein
chr8_-_85341705 0.35 ENST00000517618.5
CA1
carbonic anhydrase 1
chr15_+_37934626 0.35 ENST00000559502.5
ENST00000558148.5
ENST00000319669.5
ENST00000558158.5
TMCO5A
transmembrane and coiled-coil domains 5A
chr8_+_97887903 0.35 ENST00000520016.5
MATN2
matrilin 2
chr6_-_111605859 0.34 ENST00000651359.1
ENST00000650859.1
ENST00000359831.8
ENST00000368761.11
TRAF3IP2
TRAF3 interacting protein 2
chr7_-_105691637 0.34 ENST00000472195.1
ATXN7L1
ataxin 7 like 1
chr3_+_98168700 0.32 ENST00000383696.4
OR5H15
olfactory receptor family 5 subfamily H member 15
chr17_+_7857987 0.32 ENST00000332439.5
CYB5D1
cytochrome b5 domain containing 1
chr9_-_13175824 0.32 ENST00000545857.5
MPDZ
multiple PDZ domain crumbs cell polarity complex component
chr14_-_100375333 0.32 ENST00000557297.5
ENST00000555813.5
ENST00000392882.7
ENST00000557135.5
ENST00000556698.5
ENST00000554509.5
ENST00000555410.5
WARS1
tryptophanyl-tRNA synthetase 1
chr14_-_24508251 0.30 ENST00000250378.7
ENST00000206446.4
CMA1
chymase 1
chr22_-_28306645 0.28 ENST00000612946.4
TTC28
tetratricopeptide repeat domain 28
chr1_+_162381703 0.28 ENST00000458626.4
C1orf226
chromosome 1 open reading frame 226
chr17_+_35844077 0.28 ENST00000604694.1
TAF15
TATA-box binding protein associated factor 15
chr6_-_27873525 0.27 ENST00000618305.2
H4C13
H4 clustered histone 13
chr1_+_15756659 0.27 ENST00000375771.5
FBLIM1
filamin binding LIM protein 1
chr22_-_35617321 0.27 ENST00000397326.7
ENST00000442617.1
MB
myoglobin
chr7_-_5959083 0.27 ENST00000539903.5
RSPH10B
radial spoke head 10 homolog B
chr1_-_158554405 0.27 ENST00000641282.1
ENST00000641622.1
OR6Y1
olfactory receptor family 6 subfamily Y member 1
chr12_-_7503744 0.26 ENST00000396620.7
ENST00000432237.3
CD163
CD163 molecule
chr16_+_82035245 0.26 ENST00000199936.9
HSD17B2
hydroxysteroid 17-beta dehydrogenase 2
chr21_-_30492008 0.26 ENST00000334063.6
KRTAP19-3
keratin associated protein 19-3
chr1_+_152719522 0.26 ENST00000368775.3
C1orf68
chromosome 1 open reading frame 68
chr2_+_48617798 0.25 ENST00000448460.5
ENST00000437125.5
ENST00000430487.6
GTF2A1L
general transcription factor IIA subunit 1 like
chr2_+_137964279 0.25 ENST00000329366.8
HNMT
histamine N-methyltransferase
chr2_+_108588286 0.25 ENST00000332345.10
LIMS1
LIM zinc finger domain containing 1
chr14_-_75069478 0.25 ENST00000555463.1
ACYP1
acylphosphatase 1
chr4_-_149815826 0.24 ENST00000636793.2
ENST00000636414.1
IQCM
IQ motif containing M
chr16_-_74607088 0.24 ENST00000565260.1
ENST00000447066.6
ENST00000205061.9
ENST00000422840.7
ENST00000627032.2
GLG1
golgi glycoprotein 1
chr7_+_73667824 0.24 ENST00000324941.5
ENST00000451519.1
VPS37D
VPS37D subunit of ESCRT-I
chr17_-_7857854 0.23 ENST00000333775.9
NAA38
N-alpha-acetyltransferase 38, NatC auxiliary subunit
chr17_+_39700046 0.23 ENST00000269571.10
ERBB2
erb-b2 receptor tyrosine kinase 2
chr17_-_7857938 0.23 ENST00000575208.2
NAA38
N-alpha-acetyltransferase 38, NatC auxiliary subunit
chrX_-_149595314 0.23 ENST00000598963.3
HSFX2
heat shock transcription factor family, X-linked 2
chr11_+_33016106 0.23 ENST00000311388.7
DEPDC7
DEP domain containing 7
chr19_-_35228699 0.23 ENST00000324675.3
FAM187B
family with sequence similarity 187 member B
chr15_-_44194407 0.22 ENST00000484674.5
FRMD5
FERM domain containing 5
chr5_+_161850597 0.21 ENST00000634335.1
ENST00000635880.1
GABRA1
gamma-aminobutyric acid type A receptor subunit alpha1
chr16_+_67570741 0.21 ENST00000644753.1
ENST00000642819.1
ENST00000645306.1
CTCF
CCCTC-binding factor
chr9_+_137086857 0.21 ENST00000682881.1
ENST00000683324.1
ENST00000542372.2
ENST00000683355.1
ENST00000682117.1
ENST00000682212.1
ENST00000684144.1
ENST00000683987.1
ENST00000371589.9
ENST00000535144.6
ENST00000475449.7
ENST00000684759.1
MAN1B1
mannosidase alpha class 1B member 1
chr11_+_104036624 0.21 ENST00000302259.5
DDI1
DNA damage inducible 1 homolog 1
chr9_-_35079923 0.20 ENST00000378643.8
ENST00000448890.1
FANCG
FA complementation group G
chr3_-_58433810 0.20 ENST00000474765.1
ENST00000485460.5
ENST00000302746.11
ENST00000383714.8
PDHB
pyruvate dehydrogenase E1 subunit beta
chr3_-_185821092 0.20 ENST00000421047.3
IGF2BP2
insulin like growth factor 2 mRNA binding protein 2
chr5_+_147878703 0.20 ENST00000296694.5
SCGB3A2
secretoglobin family 3A member 2
chr14_+_22462932 0.19 ENST00000390477.2
TRDC
T cell receptor delta constant
chr9_-_110337808 0.19 ENST00000374510.8
ENST00000374507.4
ENST00000423740.7
ENST00000374511.7
TXNDC8
thioredoxin domain containing 8
chr2_+_233729042 0.19 ENST00000482026.6
UGT1A3
UDP glucuronosyltransferase family 1 member A3
chrX_-_100874351 0.19 ENST00000372966.8
NOX1
NADPH oxidase 1
chr13_+_34942263 0.18 ENST00000379939.7
ENST00000400445.7
NBEA
neurobeachin
chr3_-_123980727 0.17 ENST00000620893.4
ROPN1
rhophilin associated tail protein 1
chr4_-_69639642 0.17 ENST00000604629.6
ENST00000604021.1
UGT2A2
UDP glucuronosyltransferase family 2 member A2
chr2_-_46617020 0.17 ENST00000474980.1
ENST00000281382.11
ENST00000306465.8
PIGF
phosphatidylinositol glycan anchor biosynthesis class F
chr10_+_99782628 0.16 ENST00000648689.1
ENST00000647814.1
ABCC2
ATP binding cassette subfamily C member 2
chr17_+_36064265 0.16 ENST00000616054.2
CCL18
C-C motif chemokine ligand 18
chr16_+_33459650 0.16 ENST00000617705.1
TP53TG3F
TP53 target 3 family member F
chr19_-_46654657 0.16 ENST00000300875.4
DACT3
dishevelled binding antagonist of beta catenin 3
chr14_-_105845677 0.16 ENST00000390556.6
IGHD
immunoglobulin heavy constant delta
chr5_-_72507354 0.16 ENST00000414109.2
ENST00000318442.6
ZNF366
zinc finger protein 366
chr2_+_46617180 0.15 ENST00000238892.4
CRIPT
CXXC repeat containing interactor of PDZ3 domain
chr3_-_114624921 0.15 ENST00000393785.6
ZBTB20
zinc finger and BTB domain containing 20
chr5_+_73813518 0.15 ENST00000296799.8
ARHGEF28
Rho guanine nucleotide exchange factor 28
chr12_-_123272234 0.15 ENST00000544658.5
CDK2AP1
cyclin dependent kinase 2 associated protein 1
chr4_+_82900679 0.15 ENST00000302236.10
THAP9
THAP domain containing 9
chr18_+_22933819 0.15 ENST00000399722.6
ENST00000399725.6
ENST00000399721.6
RBBP8
RB binding protein 8, endonuclease
chr14_-_64823148 0.14 ENST00000389722.7
SPTB
spectrin beta, erythrocytic
chr7_+_143959927 0.14 ENST00000624504.1
OR2F1
olfactory receptor family 2 subfamily F member 1
chr10_-_95069489 0.14 ENST00000371270.6
ENST00000535898.5
ENST00000623108.3
CYP2C8
cytochrome P450 family 2 subfamily C member 8
chr4_+_113292838 0.14 ENST00000672411.1
ENST00000673231.1
ANK2
ankyrin 2
chrX_-_24027186 0.14 ENST00000328046.8
KLHL15
kelch like family member 15
chr5_-_138875290 0.13 ENST00000521094.2
ENST00000274711.7
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr6_+_46693835 0.13 ENST00000450697.1
TDRD6
tudor domain containing 6
chr21_+_42403856 0.13 ENST00000291535.11
UBASH3A
ubiquitin associated and SH3 domain containing A
chr17_+_997101 0.13 ENST00000327158.5
TIMM22
translocase of inner mitochondrial membrane 22
chr17_-_58353069 0.13 ENST00000580947.1
SUPT4H1
SPT4 homolog, DSIF elongation factor subunit
chr3_+_51975026 0.12 ENST00000458031.6
ENST00000273596.8
ENST00000463937.1
ENST00000635952.1
ABHD14A
ABHD14A-ACY1
abhydrolase domain containing 14A
ABHD14A-ACY1 readthrough
chr21_+_42403874 0.12 ENST00000319294.11
ENST00000398367.1
UBASH3A
ubiquitin associated and SH3 domain containing A
chr4_+_113292925 0.12 ENST00000673353.1
ENST00000505342.6
ENST00000672915.1
ENST00000509550.5
ANK2
ankyrin 2
chr4_+_48805137 0.12 ENST00000504654.5
OCIAD1
OCIA domain containing 1
chr21_-_30166782 0.12 ENST00000286808.5
CLDN17
claudin 17
chr3_-_114624979 0.12 ENST00000676079.1
ZBTB20
zinc finger and BTB domain containing 20
chr16_-_69339493 0.12 ENST00000562595.5
ENST00000615447.1
ENST00000306875.10
ENST00000562081.2
COG8
component of oligomeric golgi complex 8
chr7_-_150323489 0.12 ENST00000683684.1
ENST00000478393.5
ACTR3C
actin related protein 3C
chr8_+_12104389 0.11 ENST00000400085.7
ZNF705D
zinc finger protein 705D
chr16_+_81238682 0.11 ENST00000258168.7
ENST00000564552.1
BCO1
beta-carotene oxygenase 1
chr20_+_45207025 0.11 ENST00000372781.4
SEMG1
semenogelin 1
chr6_-_159044980 0.10 ENST00000367066.8
TAGAP
T cell activation RhoGTPase activating protein
chr7_-_83649097 0.10 ENST00000643230.2
SEMA3E
semaphorin 3E
chr7_+_100088957 0.10 ENST00000303904.8
ENST00000419210.1
ENST00000418625.5
COPS6
COP9 signalosome subunit 6
chr13_-_21459253 0.10 ENST00000400590.8
ENST00000382466.7
ENST00000415724.2
ENST00000542645.5
ZDHHC20
zinc finger DHHC-type palmitoyltransferase 20
chr17_-_3433841 0.09 ENST00000248384.1
OR1E2
olfactory receptor family 1 subfamily E member 2
chr16_-_71289609 0.09 ENST00000338099.9
ENST00000563876.1
CMTR2
cap methyltransferase 2
chr4_-_127965930 0.08 ENST00000641447.1
ENST00000296468.8
ENST00000641134.1
ENST00000641147.1
ENST00000641178.1
MFSD8
major facilitator superfamily domain containing 8
chr3_-_194351290 0.08 ENST00000429275.1
ENST00000323830.4
CPN2
carboxypeptidase N subunit 2
chr20_+_45221362 0.08 ENST00000372769.4
SEMG2
semenogelin 2
chr10_-_73358709 0.08 ENST00000340329.7
CFAP70
cilia and flagella associated protein 70
chr1_-_112618204 0.07 ENST00000369664.1
ST7L
suppression of tumorigenicity 7 like
chr6_-_159045104 0.07 ENST00000326965.7
TAGAP
T cell activation RhoGTPase activating protein
chr6_+_29396555 0.07 ENST00000623183.1
OR12D2
olfactory receptor family 12 subfamily D member 2
chr1_+_67207614 0.06 ENST00000425614.3
IL23R
interleukin 23 receptor
chr4_-_167234266 0.05 ENST00000511269.5
ENST00000506697.5
ENST00000512042.1
SPOCK3
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr5_-_95081482 0.05 ENST00000312216.12
ENST00000512425.5
ENST00000505208.5
ENST00000429576.6
ENST00000508509.5
ENST00000510732.5
MCTP1
multiple C2 and transmembrane domain containing 1
chr1_+_166989089 0.05 ENST00000367870.6
MAEL
maelstrom spermatogenic transposon silencer
chr12_-_91178520 0.05 ENST00000425043.5
ENST00000420120.6
ENST00000441303.6
ENST00000456569.2
DCN
decorin
chr7_-_108130349 0.05 ENST00000205386.8
ENST00000418464.1
ENST00000388781.8
LAMB4
laminin subunit beta 4
chrX_-_21658324 0.05 ENST00000379499.3
KLHL34
kelch like family member 34
chrX_-_49186328 0.05 ENST00000599218.6
ENST00000376317.4
PRICKLE3
prickle planar cell polarity protein 3
chr7_+_72925075 0.05 ENST00000434423.5
POM121
POM121 transmembrane nucleoporin
chr16_+_58392391 0.05 ENST00000426538.6
ENST00000328514.11
GINS3
GINS complex subunit 3
chr5_-_83720813 0.05 ENST00000515590.1
ENST00000274341.9
HAPLN1
hyaluronan and proteoglycan link protein 1
chr4_-_22443110 0.05 ENST00000508133.5
ADGRA3
adhesion G protein-coupled receptor A3
chr18_+_52752032 0.04 ENST00000412726.5
ENST00000578080.1
ENST00000582875.1
DCC
DCC netrin 1 receptor
chr4_+_186266183 0.04 ENST00000403665.7
ENST00000492972.6
ENST00000264692.8
F11
coagulation factor XI
chr4_+_188139438 0.04 ENST00000332517.4
TRIML1
tripartite motif family like 1
chr11_+_111255982 0.04 ENST00000637637.1
C11orf53
chromosome 11 open reading frame 53
chr6_-_22302826 0.04 ENST00000651245.1
PRL
prolactin
chrX_-_100874209 0.04 ENST00000372964.5
ENST00000217885.5
NOX1
NADPH oxidase 1
chr6_-_31652678 0.04 ENST00000437771.5
ENST00000362049.10
ENST00000439687.6
ENST00000211379.9
ENST00000375964.11
ENST00000676571.1
ENST00000676615.1
BAG6
BAG cochaperone 6
chr16_+_58392462 0.04 ENST00000318129.6
GINS3
GINS complex subunit 3
chr21_-_14658812 0.04 ENST00000647101.1
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chrX_+_155997706 0.04 ENST00000369423.7
IL9R
interleukin 9 receptor
chr6_+_30940970 0.04 ENST00000462446.6
ENST00000304311.3
MUCL3
mucin like 3
chr13_-_40982880 0.04 ENST00000635415.1
ELF1
E74 like ETS transcription factor 1
chr7_+_69967464 0.03 ENST00000664521.1
AUTS2
activator of transcription and developmental regulator AUTS2
chr1_-_206921987 0.03 ENST00000530505.1
ENST00000442471.4
FCMR
Fc fragment of IgM receptor
chr21_-_44801769 0.03 ENST00000330942.9
UBE2G2
ubiquitin conjugating enzyme E2 G2
chr19_-_39846329 0.03 ENST00000599134.1
ENST00000597634.5
ENST00000598417.5
ENST00000601274.5
ENST00000594309.5
ENST00000221801.8
FBL
fibrillarin
chr9_-_21217311 0.03 ENST00000380216.1
IFNA16
interferon alpha 16
chr1_+_166989254 0.03 ENST00000367872.9
ENST00000447624.1
MAEL
maelstrom spermatogenic transposon silencer
chr2_-_233013228 0.03 ENST00000264051.8
NGEF
neuronal guanine nucleotide exchange factor
chrX_+_155997581 0.03 ENST00000244174.10
IL9R
interleukin 9 receptor
chr17_+_76079182 0.02 ENST00000334586.10
ZACN
zinc activated ion channel
chr2_+_112721486 0.02 ENST00000327581.4
NT5DC4
5'-nucleotidase domain containing 4
chr19_-_41959266 0.02 ENST00000600292.5
ENST00000601078.5
ENST00000601891.5
ENST00000222008.11
RABAC1
Rab acceptor 1
chr20_-_31390483 0.02 ENST00000376315.2
DEFB119
defensin beta 119
chr7_-_130687432 0.02 ENST00000456951.5
TSGA13
testis specific 13
chr7_-_151080787 0.02 ENST00000540185.5
ENST00000297532.11
FASTK
Fas activated serine/threonine kinase
chr2_+_170178136 0.01 ENST00000409044.7
ENST00000408978.9
MYO3B
myosin IIIB
chr1_-_149812359 0.01 ENST00000369167.2
ENST00000545683.1
H2BC18
H2B clustered histone 18
chr6_+_27957241 0.01 ENST00000244623.1
OR2B6
olfactory receptor family 2 subfamily B member 6
chr7_-_151080833 0.01 ENST00000353841.6
ENST00000482571.2
FASTK
Fas activated serine/threonine kinase
chr10_+_125973373 0.01 ENST00000417114.5
ENST00000445510.5
ENST00000368691.5
FANK1
fibronectin type III and ankyrin repeat domains 1
chr4_+_56505782 0.00 ENST00000640821.3
ARL9
ADP ribosylation factor like GTPase 9
chr2_-_88861258 0.00 ENST00000390240.2
IGKJ3
immunoglobulin kappa joining 3
chr7_+_95485934 0.00 ENST00000325885.6
ASB4
ankyrin repeat and SOCS box containing 4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 GO:0060352 cell adhesion molecule production(GO:0060352)
0.1 0.6 GO:0001692 histamine metabolic process(GO:0001692)
0.1 0.3 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.1 0.6 GO:0097338 response to clozapine(GO:0097338)
0.1 0.8 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.4 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.1 0.2 GO:1990451 cellular stress response to acidic pH(GO:1990451)
0.1 0.2 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.1 0.5 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.4 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.2 GO:0016999 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
0.0 0.2 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.0 0.2 GO:1900005 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.0 0.3 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.6 GO:0032310 innate immune response in mucosa(GO:0002227) positive regulation of guanylate cyclase activity(GO:0031284) prostaglandin secretion(GO:0032310)
0.0 0.1 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 0.5 GO:0045008 depyrimidination(GO:0045008)
0.0 0.1 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.1 GO:0016119 carotene metabolic process(GO:0016119)
0.0 0.2 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.3 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.8 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.4 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.3 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 1.2 GO:0046039 GTP metabolic process(GO:0046039)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.2 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.1 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.5 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.2 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.2 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 0.9 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.3 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.0 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.0 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.8 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.0 GO:1990258 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.0 GO:1904379 tail-anchored membrane protein insertion into ER membrane(GO:0071816) protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0031417 NatC complex(GO:0031417)
0.0 0.9 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0030849 autosome(GO:0030849)
0.0 0.1 GO:0032044 DSIF complex(GO:0032044)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 1.7 GO:0031985 Golgi cisterna(GO:0031985)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.0 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.2 0.9 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.1 0.6 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.9 GO:0004064 arylesterase activity(GO:0004064)
0.1 0.3 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.1 0.9 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.2 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.1 0.4 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.5 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.4 GO:0031013 troponin I binding(GO:0031013)
0.0 0.2 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.8 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.5 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.2 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.0 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.4 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.6 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 1.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis