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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for ISL1

Z-value: 0.59

Motif logo

Transcription factors associated with ISL1

Gene Symbol Gene ID Gene Info
ENSG00000016082.15 ISL1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ISL1hg38_v1_chr5_+_51383394_51383454-0.106.4e-01Click!

Activity profile of ISL1 motif

Sorted Z-values of ISL1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ISL1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr4_-_185956652 3.34 ENST00000355634.9
sorbin and SH3 domain containing 2
chr1_+_99646025 3.16 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
palmdelphin
chr6_-_129710145 2.90 ENST00000368149.3
Rho GTPase activating protein 18
chr4_-_185956348 2.53 ENST00000431902.5
ENST00000284776.11
ENST00000415274.5
sorbin and SH3 domain containing 2
chr1_+_81800368 1.43 ENST00000674489.1
ENST00000674442.1
ENST00000674419.1
ENST00000674407.1
ENST00000674168.1
ENST00000674307.1
ENST00000674209.1
ENST00000370715.5
ENST00000370713.5
ENST00000319517.10
ENST00000627151.2
ENST00000370717.6
adhesion G protein-coupled receptor L2
chr10_-_114684612 1.40 ENST00000533213.6
ENST00000369252.8
actin binding LIM protein 1
chr8_-_3409528 1.38 ENST00000335551.11
CUB and Sushi multiple domains 1
chr17_-_55511434 1.26 ENST00000636752.1
small integral membrane protein 36
chrX_-_117973717 1.25 ENST00000262820.7
kelch like family member 13
chr2_+_172860038 1.25 ENST00000538974.5
ENST00000540783.5
Rap guanine nucleotide exchange factor 4
chr9_-_14300231 1.21 ENST00000636735.1
nuclear factor I B
chrX_-_117973579 1.16 ENST00000371878.5
kelch like family member 13
chr6_+_144583198 1.09 ENST00000367526.8
utrophin
chr6_+_143608170 0.96 ENST00000427704.6
ENST00000305766.10
phosphatase and actin regulator 2
chr2_+_172928165 0.88 ENST00000535187.5
Rap guanine nucleotide exchange factor 4
chrX_+_136169833 0.88 ENST00000628032.2
four and a half LIM domains 1
chr3_-_15797930 0.87 ENST00000683139.1
ankyrin repeat domain 28
chr17_+_68525795 0.86 ENST00000592800.5
protein kinase cAMP-dependent type I regulatory subunit alpha
chr12_+_78864768 0.86 ENST00000261205.9
ENST00000457153.6
synaptotagmin 1
chr13_-_99016034 0.81 ENST00000448493.7
dedicator of cytokinesis 9
chr8_+_22053543 0.80 ENST00000519850.5
ENST00000381470.7
dematin actin binding protein
chr3_-_185821092 0.76 ENST00000421047.3
insulin like growth factor 2 mRNA binding protein 2
chr12_-_42484298 0.75 ENST00000640055.1
ENST00000639566.1
ENST00000455697.6
ENST00000639589.1
prickle planar cell polarity protein 1
chrX_+_136169664 0.74 ENST00000456445.5
four and a half LIM domains 1
chr8_-_19682576 0.74 ENST00000332246.10
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr9_+_131096476 0.71 ENST00000372309.7
ENST00000247291.8
ENST00000372302.5
ENST00000372300.5
ENST00000372298.1
allograft inflammatory factor 1 like
chrX_+_55452119 0.71 ENST00000342972.3
MAGE family member H1
chr18_-_55423757 0.70 ENST00000675707.1
transcription factor 4
chrX_+_136169624 0.70 ENST00000394153.6
four and a half LIM domains 1
chr9_+_133459965 0.68 ENST00000540581.5
ENST00000542192.5
ENST00000291722.11
ENST00000316948.9
calcium channel flower domain containing 1
chr9_-_109119915 0.66 ENST00000374586.8
transmembrane protein 245
chr12_+_78863962 0.65 ENST00000393240.7
synaptotagmin 1
chr16_+_20764036 0.61 ENST00000440284.6
acyl-CoA synthetase medium chain family member 3
chr3_+_148791058 0.58 ENST00000491148.5
carboxypeptidase B1
chrX_+_136197039 0.57 ENST00000370683.6
four and a half LIM domains 1
chr5_+_73813518 0.57 ENST00000296799.8
Rho guanine nucleotide exchange factor 28
chr16_+_20763990 0.57 ENST00000289416.10
acyl-CoA synthetase medium chain family member 3
chr6_-_110815152 0.52 ENST00000413605.6
cyclin dependent kinase 19
chr18_-_55510753 0.52 ENST00000543082.5
transcription factor 4
chr8_+_69492793 0.52 ENST00000616868.1
ENST00000419716.7
ENST00000402687.9
sulfatase 1
chr2_+_28395511 0.50 ENST00000436647.1
FOS like 2, AP-1 transcription factor subunit
chr6_+_36029082 0.50 ENST00000472333.1
mitogen-activated protein kinase 14
chr6_-_116254063 0.49 ENST00000420283.3
TSPY like 4
chr6_-_110815408 0.48 ENST00000368911.8
cyclin dependent kinase 19
chr6_+_89562308 0.47 ENST00000522441.5
ankyrin repeat domain 6
chr13_+_102845835 0.44 ENST00000652613.1
ERCC excision repair 5, endonuclease
chr1_+_196652022 0.43 ENST00000367429.9
ENST00000630130.2
ENST00000359637.2
complement factor H
chr6_-_111483700 0.43 ENST00000435970.5
ENST00000358835.7
REV3 like, DNA directed polymerase zeta catalytic subunit
chr19_-_17377334 0.39 ENST00000252590.9
ENST00000599426.1
plasmalemma vesicle associated protein
chr7_-_78489900 0.39 ENST00000636039.1
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr5_-_95081482 0.38 ENST00000312216.12
ENST00000512425.5
ENST00000505208.5
ENST00000429576.6
ENST00000508509.5
ENST00000510732.5
multiple C2 and transmembrane domain containing 1
chr12_-_95116967 0.38 ENST00000551521.5
FYVE, RhoGEF and PH domain containing 6
chr17_-_21253398 0.37 ENST00000611551.1
N-acetyltransferase domain containing 1
chr17_-_41315706 0.36 ENST00000334202.5
keratin associated protein 17-1
chr6_+_42929127 0.32 ENST00000394142.7
canopy FGF signaling regulator 3
chr10_-_93482194 0.32 ENST00000358334.9
ENST00000371488.3
myoferlin
chr19_-_42255119 0.31 ENST00000222329.9
ENST00000594664.1
ETS2 repressor factor
novel protein
chr2_+_241350087 0.30 ENST00000451310.1
septin 2
chr5_+_175861628 0.30 ENST00000509837.5
complexin 2
chr10_-_93482326 0.30 ENST00000359263.9
myoferlin
chr7_+_151114597 0.30 ENST00000335367.7
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr17_-_15598618 0.29 ENST00000583965.5
CMT1A duplicated region transcript 1
chr3_+_57890011 0.28 ENST00000494088.6
ENST00000438794.5
sarcolemma associated protein
chr12_+_119668109 0.27 ENST00000229328.10
ENST00000630317.1
protein kinase AMP-activated non-catalytic subunit beta 1
chr14_-_77028663 0.27 ENST00000238647.5
interferon regulatory factor 2 binding protein like
chrX_+_136169891 0.26 ENST00000449474.5
four and a half LIM domains 1
chr5_+_122129597 0.26 ENST00000514925.1
novel zinc finger protein
chr14_-_36582593 0.26 ENST00000258829.6
NK2 homeobox 8
chr18_+_48539017 0.26 ENST00000256413.8
cap binding complex dependent translation initiation factor
chrY_-_6872608 0.26 ENST00000383036.1
amelogenin Y-linked
chr3_-_138594129 0.26 ENST00000485115.1
ENST00000484888.5
ENST00000468900.5
ENST00000481834.5
ENST00000264982.8
centrosomal protein 70
chr9_-_110337808 0.25 ENST00000374510.8
ENST00000374507.4
ENST00000423740.7
ENST00000374511.7
thioredoxin domain containing 8
chr6_+_168017873 0.25 ENST00000351261.4
ENST00000354419.6
kinesin family member 25
chr14_-_106360320 0.24 ENST00000390615.2
immunoglobulin heavy variable 3-33
chr3_+_159069252 0.24 ENST00000640015.1
ENST00000476809.7
ENST00000485419.7
IQCJ-SCHIP1 readthrough
chr4_-_127965930 0.24 ENST00000641447.1
ENST00000296468.8
ENST00000641134.1
ENST00000641147.1
ENST00000641178.1
major facilitator superfamily domain containing 8
chr5_+_140841183 0.23 ENST00000378123.4
ENST00000531613.2
protocadherin alpha 8
chr3_-_100993507 0.23 ENST00000284322.10
ABI family member 3 binding protein
chr5_-_63962438 0.23 ENST00000323865.5
ENST00000506598.1
5-hydroxytryptamine receptor 1A
chr3_-_124887353 0.23 ENST00000296181.9
integrin subunit beta 5
chr3_-_100993409 0.22 ENST00000471714.6
ABI family member 3 binding protein
chr5_+_134846065 0.22 ENST00000504727.1
ENST00000435259.2
ENST00000508791.1
chromosome 5 open reading frame 24
chr9_+_131289685 0.22 ENST00000372264.4
phospholipid phosphatase 7 (inactive)
chr8_-_78805306 0.22 ENST00000639719.1
ENST00000263851.9
interleukin 7
chr13_-_75366973 0.22 ENST00000648194.1
TBC1 domain family member 4
chr5_+_103120149 0.22 ENST00000515845.5
ENST00000321521.13
ENST00000507921.5
diphosphoinositol pentakisphosphate kinase 2
chr1_+_161766282 0.21 ENST00000680688.1
activating transcription factor 6
chr9_+_27109135 0.21 ENST00000519097.5
ENST00000615002.4
TEK receptor tyrosine kinase
chr20_-_50115935 0.21 ENST00000340309.7
ENST00000415862.6
ENST00000371677.7
ubiquitin conjugating enzyme E2 V1
chr5_+_140868945 0.20 ENST00000398640.7
protocadherin alpha 11
chr6_+_43014103 0.20 ENST00000244670.12
ENST00000326974.9
ENST00000332245.9
kelch domain containing 3
chr1_+_161766309 0.20 ENST00000679853.1
ENST00000681492.1
ENST00000679886.1
ENST00000367942.4
ENST00000680462.1
ENST00000680633.1
ENST00000681912.1
activating transcription factor 6
chr8_-_100559702 0.20 ENST00000520311.5
ENST00000520552.5
ENST00000521345.1
ENST00000523000.5
ENST00000335659.7
ENST00000358990.3
ENST00000519597.5
ankyrin repeat domain 46
chr15_+_65530418 0.20 ENST00000562901.5
ENST00000261875.10
ENST00000442729.6
ENST00000565299.5
ENST00000568793.5
3-hydroxyacyl-CoA dehydratase 3
chr1_+_156054761 0.19 ENST00000368305.9
ENST00000368304.9
ENST00000368302.3
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr13_+_108218366 0.19 ENST00000375898.4
abhydrolase domain containing 13
chrX_+_51893533 0.19 ENST00000375722.5
ENST00000326587.12
ENST00000375695.2
MAGE family member D1
chr6_+_36885944 0.19 ENST00000480824.7
chromosome 6 open reading frame 89
chr5_+_43602648 0.19 ENST00000505678.6
ENST00000512422.5
ENST00000264663.9
ENST00000670904.1
ENST00000653251.1
nicotinamide nucleotide transhydrogenase
chr6_+_31655888 0.19 ENST00000375916.4
apolipoprotein M
chr18_+_48539112 0.18 ENST00000382998.8
cap binding complex dependent translation initiation factor
chr10_+_17228215 0.18 ENST00000544301.7
vimentin
chr1_-_234479131 0.18 ENST00000040877.2
TAR (HIV-1) RNA binding protein 1
chr5_-_138875290 0.18 ENST00000521094.2
ENST00000274711.7
leucine rich repeat transmembrane neuronal 2
chr3_-_157503375 0.18 ENST00000362010.7
ventricular zone expressed PH domain containing 1
chr4_+_122378966 0.17 ENST00000446706.5
ENST00000296513.7
adenosine deaminase domain containing 1
chr4_+_118034480 0.17 ENST00000296499.6
N-deacetylase and N-sulfotransferase 3
chr9_+_37667997 0.17 ENST00000539465.5
FERM and PDZ domain containing 1
chr9_+_27109200 0.17 ENST00000380036.10
TEK receptor tyrosine kinase
chr12_-_102197827 0.17 ENST00000329406.5
pro-melanin concentrating hormone
chr1_-_113887574 0.17 ENST00000393316.8
BCL2 like 15
chr6_+_31739948 0.17 ENST00000375755.8
ENST00000425703.5
ENST00000375750.9
ENST00000375703.7
ENST00000375740.7
mutS homolog 5
chr3_-_157503339 0.17 ENST00000392833.6
ventricular zone expressed PH domain containing 1
chr8_-_78805515 0.17 ENST00000379113.6
ENST00000541183.2
interleukin 7
chr5_+_32710630 0.17 ENST00000326958.5
natriuretic peptide receptor 3
chr11_-_107457801 0.16 ENST00000282251.9
CWF19 like cell cycle control factor 2
chr2_-_96740034 0.16 ENST00000264963.9
ENST00000377079.8
lectin, mannose binding 2 like
chr5_+_140875299 0.16 ENST00000613593.1
ENST00000398631.3
protocadherin alpha 12
chr18_-_21703688 0.15 ENST00000584464.1
ENST00000578270.5
abhydrolase domain containing 3, phospholipase
chr3_+_130560334 0.15 ENST00000358511.10
collagen type VI alpha 6 chain
chr5_+_141213919 0.15 ENST00000341948.6
protocadherin beta 13
chr1_+_56854764 0.15 ENST00000361249.4
complement C8 alpha chain
chr14_+_21990357 0.15 ENST00000390444.1
T cell receptor alpha variable 16
chr12_-_54419259 0.15 ENST00000293379.9
integrin subunit alpha 5
chr3_-_143848442 0.14 ENST00000474151.1
ENST00000316549.11
solute carrier family 9 member A9
chr11_+_22666604 0.14 ENST00000454584.6
growth arrest specific 2
chr12_+_96489569 0.14 ENST00000524981.9
cilia and flagella associated protein 54
chr17_-_59151794 0.14 ENST00000584089.1
spindle and kinetochore associated complex subunit 2
chr12_-_27971970 0.14 ENST00000395872.5
ENST00000201015.8
parathyroid hormone like hormone
chr11_+_57805541 0.14 ENST00000683201.1
ENST00000683769.1
catenin delta 1
chr8_-_42377227 0.13 ENST00000220812.3
dickkopf WNT signaling pathway inhibitor 4
chr1_+_197413827 0.13 ENST00000367397.1
ENST00000681519.1
crumbs cell polarity complex component 1
chr9_-_92404559 0.13 ENST00000262551.8
ENST00000375561.10
osteoglycin
chr4_-_73223082 0.13 ENST00000509867.6
ankyrin repeat domain 17
chr4_-_86360010 0.13 ENST00000641911.1
ENST00000641072.1
ENST00000359221.8
ENST00000640490.1
mitogen-activated protein kinase 10
chr2_-_166149204 0.12 ENST00000635750.1
sodium voltage-gated channel alpha subunit 1
chr10_-_18651576 0.12 ENST00000377304.7
NOP2/Sun RNA methyltransferase 6
chr2_-_166149120 0.12 ENST00000641575.1
ENST00000641603.1
sodium voltage-gated channel alpha subunit 1
chr21_-_46155567 0.12 ENST00000291670.9
ENST00000397748.5
ENST00000397743.1
ENST00000397746.8
formimidoyltransferase cyclodeaminase
chr14_-_106538331 0.11 ENST00000390624.3
immunoglobulin heavy variable 3-48
chr11_-_75096876 0.11 ENST00000641541.1
ENST00000641593.1
ENST00000641504.1
ENST00000641931.1
ENST00000647690.1
olfactory receptor family 2 subfamily AT member 4
novel transcript
chr5_+_141370236 0.11 ENST00000576222.2
ENST00000618934.1
protocadherin gamma subfamily B, 3
chr8_+_26390362 0.11 ENST00000518611.5
BCL2 interacting protein 3 like
chr6_+_36885848 0.10 ENST00000355190.7
ENST00000373685.1
chromosome 6 open reading frame 89
chr4_-_176002332 0.10 ENST00000280187.11
ENST00000512509.5
glycoprotein M6A
chr1_-_156248013 0.10 ENST00000368270.2
progestin and adipoQ receptor family member 6
chr13_+_77741160 0.09 ENST00000314070.9
ENST00000351546.7
SLAIN motif family member 1
chr1_-_204166334 0.09 ENST00000272190.9
renin
chr12_-_23949642 0.09 ENST00000537393.5
ENST00000451604.7
ENST00000381381.6
SRY-box transcription factor 5
chrX_+_21940693 0.09 ENST00000404933.7
ENST00000379404.5
spermine synthase
chr9_-_179008 0.09 ENST00000613508.4
ENST00000382447.8
ENST00000382389.5
ENST00000377447.7
ENST00000382393.2
ENST00000314367.14
ENST00000356521.8
ENST00000377400.8
COBW domain containing 1
chr6_-_116829037 0.09 ENST00000368549.7
ENST00000530250.1
ENST00000310357.8
G protein-coupled receptor class C group 6 member A
chr12_+_57610150 0.09 ENST00000333972.11
Rho guanine nucleotide exchange factor 25
chr11_+_560956 0.09 ENST00000397582.7
ENST00000397583.8
Ras association domain family member 7
chr8_+_109086585 0.09 ENST00000518632.2
thyrotropin releasing hormone receptor
chr20_+_43507668 0.09 ENST00000434666.5
ENST00000649084.1
ENST00000418998.7
ENST00000427442.8
ENST00000649917.1
L3MBTL histone methyl-lysine binding protein 1
chrX_-_134658450 0.08 ENST00000359237.9
placenta enriched 1
chr4_+_56436233 0.08 ENST00000512576.3
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
chr1_+_192575765 0.08 ENST00000469578.2
ENST00000367459.8
regulator of G protein signaling 1
chr8_-_132625378 0.08 ENST00000522789.5
leucine rich repeat containing 6
chr1_-_156248038 0.08 ENST00000470198.5
ENST00000292291.10
ENST00000356983.7
progestin and adipoQ receptor family member 6
chr1_-_156248084 0.07 ENST00000652405.1
ENST00000335852.6
ENST00000540423.5
ENST00000612424.4
ENST00000613336.4
ENST00000623241.3
progestin and adipoQ receptor family member 6
chr6_-_24719146 0.07 ENST00000378119.9
chromosome 6 open reading frame 62
chr22_+_29883158 0.07 ENST00000333027.7
ENST00000401950.7
ENST00000445401.5
ENST00000323630.9
ENST00000351488.7
myotubularin related protein 3
chr7_+_130293134 0.07 ENST00000445470.6
ENST00000492072.5
ENST00000222482.10
ENST00000473956.5
ENST00000493259.5
ENST00000486598.1
carboxypeptidase A4
chr14_-_59870752 0.07 ENST00000611068.1
ENST00000267484.10
reticulon 1
chr18_-_24397784 0.07 ENST00000399441.4
ENST00000319481.8
oxysterol binding protein like 1A
chrX_-_15601077 0.07 ENST00000680121.1
angiotensin I converting enzyme 2
chr12_+_94148553 0.07 ENST00000258526.9
plexin C1
chr22_+_40679273 0.07 ENST00000381433.2
melanin concentrating hormone receptor 1
chr4_-_86360039 0.07 ENST00000515650.2
ENST00000641724.1
ENST00000641607.1
ENST00000641324.1
ENST00000641903.1
ENST00000395157.9
ENST00000641823.1
ENST00000641873.1
ENST00000641102.1
ENST00000641462.2
ENST00000641217.1
ENST00000642006.1
ENST00000641020.1
ENST00000641110.1
ENST00000639175.1
ENST00000641485.1
ENST00000641864.1
ENST00000641954.1
ENST00000641647.1
ENST00000641459.1
ENST00000641762.1
ENST00000641777.1
ENST00000641208.1
ENST00000642015.1
ENST00000641493.1
ENST00000642032.1
ENST00000641010.1
ENST00000641287.1
ENST00000641943.1
ENST00000642103.1
ENST00000641047.1
ENST00000641166.1
ENST00000641207.1
mitogen-activated protein kinase 10
chrX_-_30309387 0.07 ENST00000378970.5
nuclear receptor subfamily 0 group B member 1
chr12_-_30735014 0.06 ENST00000433722.6
caprin family member 2
chr3_-_100993448 0.06 ENST00000495063.6
ENST00000486770.7
ENST00000530539.2
ABI family member 3 binding protein
chr7_+_90709530 0.06 ENST00000406263.5
cyclin dependent kinase 14
chr16_-_30787169 0.06 ENST00000262525.6
zinc finger protein 629
chr1_-_160098593 0.06 ENST00000314485.12
immunoglobulin superfamily member 8
chr12_-_6375209 0.05 ENST00000360168.7
sodium channel epithelial 1 subunit alpha
chrX_+_80420466 0.05 ENST00000308293.5
terminal nucleotidyltransferase 5D
chr17_+_37375974 0.05 ENST00000615133.2
ENST00000611038.4
chromosome 17 open reading frame 78
chr3_+_119782094 0.05 ENST00000393716.8
nuclear receptor subfamily 1 group I member 2
chr2_+_95025700 0.05 ENST00000309988.9
ENST00000353004.7
ENST00000354078.7
ENST00000349807.3
mal, T cell differentiation protein
chr16_+_33009175 0.05 ENST00000565407.2
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr1_+_84408230 0.05 ENST00000370662.3
deoxyribonuclease 2 beta
chr6_+_46793379 0.05 ENST00000230588.9
ENST00000611727.2
meprin A subunit alpha
chr15_+_42359454 0.05 ENST00000349748.8
ENST00000318023.11
ENST00000397163.8
calpain 3
chr14_+_61697622 0.04 ENST00000539097.2
hypoxia inducible factor 1 subunit alpha
chrX_-_72307148 0.04 ENST00000453707.6
ENST00000373619.7
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1
chr3_+_38265802 0.04 ENST00000311856.9
solute carrier family 22 member 13
chr12_-_91180365 0.04 ENST00000547937.5
decorin
chr7_+_143222037 0.03 ENST00000408947.4
taste 2 receptor member 40
chr7_+_90709231 0.03 ENST00000446790.5
ENST00000265741.7
cyclin dependent kinase 14
chr1_+_171248471 0.03 ENST00000402921.6
ENST00000617670.6
ENST00000367750.7
flavin containing dimethylaniline monoxygenase 1
chr10_-_30349161 0.03 ENST00000421701.1
ENST00000263063.9
mitochondrial poly(A) polymerase
chr4_-_86360071 0.03 ENST00000641677.1
ENST00000639234.1
ENST00000641553.1
ENST00000641826.1
ENST00000641537.1
ENST00000395169.9
ENST00000641408.1
ENST00000638225.1
ENST00000641052.1
mitogen-activated protein kinase 10
chr2_-_219170023 0.03 ENST00000409878.8
ENST00000455516.6
ENST00000295738.11
solute carrier family 23 member 3
chr3_-_33645433 0.03 ENST00000635664.1
ENST00000485378.6
ENST00000313350.10
ENST00000487200.5
cytoplasmic linker associated protein 2
chr1_+_103617427 0.03 ENST00000423678.2
ENST00000414303.7
amylase alpha 2A
chr2_+_225399684 0.03 ENST00000636099.1
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr2_-_74421560 0.03 ENST00000612891.4
ENST00000640331.1
ENST00000684111.1
chromosome 2 open reading frame 81

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.2 0.7 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.2 0.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 0.8 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.1 5.9 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.8 GO:0070560 protein secretion by platelet(GO:0070560)
0.1 1.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 1.1 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.5 GO:2001184 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.1 0.2 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.1 0.4 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.1 0.9 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.4 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.2 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.2 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.2 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.2 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.6 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.5 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 3.0 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.4 GO:0010225 response to UV-C(GO:0010225)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.2 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.3 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.2 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.3 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.1 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.0 0.1 GO:0070305 response to cGMP(GO:0070305)
0.0 0.1 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 1.9 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.2 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 0.2 GO:0051026 chiasma assembly(GO:0051026)
0.0 5.4 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.4 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.0 0.3 GO:0035878 nail development(GO:0035878)
0.0 0.2 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.3 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 1.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.2 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.1 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.4 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.1 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.2 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 2.4 GO:0000910 cytokinesis(GO:0000910)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 1.1 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.4 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.2 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.1 1.1 GO:0070938 contractile ring(GO:0070938)
0.1 1.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 1.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.2 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.3 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.4 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 1.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 1.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 7.2 GO:0030027 lamellipodium(GO:0030027)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 2.6 GO:0043197 dendritic spine(GO:0043197)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.3 1.5 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 5.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.7 GO:0047238 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237) glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 1.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.2 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.2 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
0.1 1.2 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.2 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0 3.0 GO:0030552 cAMP binding(GO:0030552)
0.0 0.5 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.4 GO:0000405 bubble DNA binding(GO:0000405)
0.0 1.1 GO:0017166 vinculin binding(GO:0017166)
0.0 0.0 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.3 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.2 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.2 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.0 0.1 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.2 GO:0102344 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.1 GO:0004639 phosphoribosylaminoimidazole carboxylase activity(GO:0004638) phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.2 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.8 GO:0030507 spectrin binding(GO:0030507)
0.0 0.8 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 1.1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.0 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 2.8 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.3 PID AURORA B PATHWAY Aurora B signaling
0.0 2.0 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.9 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 2.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.9 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 1.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.7 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.8 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 1.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.4 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis