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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for JDP2

Z-value: 1.33

Motif logo

Transcription factors associated with JDP2

Gene Symbol Gene ID Gene Info
ENSG00000140044.13 JDP2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
JDP2hg38_v1_chr14_+_75428011_754280460.491.3e-02Click!

Activity profile of JDP2 motif

Sorted Z-values of JDP2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of JDP2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr15_+_88638947 19.14 ENST00000559876.2
interferon stimulated exonuclease gene 20
chr15_+_88639009 16.02 ENST00000306072.10
interferon stimulated exonuclease gene 20
chr2_+_151357583 9.33 ENST00000243347.5
TNF alpha induced protein 6
chr11_-_102798148 9.21 ENST00000315274.7
matrix metallopeptidase 1
chr1_-_153549120 8.49 ENST00000368712.1
S100 calcium binding protein A3
chr12_-_104958268 8.45 ENST00000432951.1
ENST00000258538.8
ENST00000415674.1
ENST00000424946.1
ENST00000433540.5
solute carrier family 41 member 2
chr1_-_153549238 7.76 ENST00000368713.8
S100 calcium binding protein A3
chr4_-_76036060 6.42 ENST00000306621.8
C-X-C motif chemokine ligand 11
chr4_+_73740541 6.41 ENST00000401931.1
ENST00000307407.8
C-X-C motif chemokine ligand 8
chr1_+_183186238 5.13 ENST00000493293.5
ENST00000264144.5
laminin subunit gamma 2
chr5_+_35856883 4.68 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
interleukin 7 receptor
chr16_+_57628507 3.92 ENST00000456916.5
ENST00000567154.5
ENST00000388813.9
ENST00000562558.6
ENST00000566271.6
ENST00000563374.5
ENST00000673126.2
ENST00000562631.7
ENST00000568234.5
ENST00000565770.5
ENST00000566164.5
adhesion G protein-coupled receptor G1
chr8_+_85245451 3.81 ENST00000321764.4
carbonic anhydrase 13
chr4_-_121164314 3.60 ENST00000057513.8
TNFAIP3 interacting protein 3
chr16_+_57628684 3.36 ENST00000567397.5
ENST00000568979.5
ENST00000672974.1
adhesion G protein-coupled receptor G1
chr2_-_174847525 3.25 ENST00000295497.12
ENST00000652036.1
ENST00000444394.6
ENST00000650731.1
chimerin 1
chr10_+_102395693 3.24 ENST00000652277.1
ENST00000189444.11
ENST00000661543.1
nuclear factor kappa B subunit 2
chr2_-_174847765 3.23 ENST00000443238.6
chimerin 1
chr17_-_29930062 3.12 ENST00000579954.1
ENST00000269033.7
ENST00000540801.6
ENST00000590153.1
ENST00000582084.1
slingshot protein phosphatase 2
chr5_+_136058849 3.11 ENST00000508076.5
transforming growth factor beta induced
chr22_-_41285868 2.94 ENST00000422838.1
ENST00000405486.5
Ran GTPase activating protein 1
chr17_+_76385256 2.80 ENST00000392496.3
sphingosine kinase 1
chr18_+_58196736 2.64 ENST00000675221.1
NEDD4 like E3 ubiquitin protein ligase
chr18_+_24113341 2.56 ENST00000540918.2
tetratricopeptide repeat domain 39C
chr18_+_58221535 2.53 ENST00000431212.6
ENST00000586268.5
ENST00000587190.5
NEDD4 like E3 ubiquitin protein ligase
chr1_-_209651291 2.53 ENST00000391911.5
ENST00000415782.1
laminin subunit beta 3
chr10_+_113709261 2.44 ENST00000672138.1
ENST00000452490.3
caspase 7
chr7_+_28685968 2.41 ENST00000396298.6
cAMP responsive element binding protein 5
chr11_-_2929412 2.33 ENST00000314222.5
pleckstrin homology like domain family A member 2
chr4_+_85604146 2.26 ENST00000512201.5
Rho GTPase activating protein 24
chr10_-_73625951 2.13 ENST00000433394.1
ENST00000422491.7
ubiquitin specific peptidase 54
chr11_+_122655712 2.13 ENST00000284273.6
ubiquitin associated and SH3 domain containing B
chr21_-_35049238 2.04 ENST00000416754.1
ENST00000437180.5
ENST00000455571.5
ENST00000675419.1
RUNX family transcription factor 1
chr1_+_213051229 2.03 ENST00000615329.4
ENST00000543354.5
ENST00000614059.4
ENST00000543470.5
ENST00000366960.8
ENST00000366959.4
ribosomal protein S6 kinase C1
chr1_-_161132577 2.02 ENST00000464113.1
death effector domain containing
chr21_-_35049327 1.99 ENST00000300305.7
RUNX family transcription factor 1
chr10_-_25062279 1.85 ENST00000615958.4
enkurin, TRPC channel interacting protein
chr3_-_191282383 1.83 ENST00000427544.6
urotensin 2B
chr17_+_81683963 1.73 ENST00000676462.1
ENST00000679336.1
ENST00000678196.1
ENST00000677243.1
ENST00000677044.1
ENST00000677109.1
ENST00000677484.1
ENST00000678105.1
ENST00000677209.1
ENST00000329138.9
ENST00000677225.1
ENST00000678866.1
ENST00000676729.1
ENST00000572392.2
ENST00000577012.1
hepatocyte growth factor-regulated tyrosine kinase substrate
chr6_+_150721073 1.69 ENST00000358517.6
pleckstrin homology and RhoGEF domain containing G1
chr3_+_48466222 1.69 ENST00000625293.3
ENST00000492235.2
ENST00000635452.2
ENST00000456089.1
three prime repair exonuclease 1
chr6_+_45328203 1.65 ENST00000371432.7
ENST00000647337.2
ENST00000371438.5
RUNX family transcription factor 2
chr1_-_161132659 1.62 ENST00000368006.8
ENST00000490843.6
ENST00000545495.5
death effector domain containing
chr3_-_196270540 1.55 ENST00000419333.5
phosphate cytidylyltransferase 1, choline, alpha
chr2_+_74529923 1.52 ENST00000258080.8
ENST00000352222.7
HtrA serine peptidase 2
chr17_+_4950147 1.50 ENST00000522301.5
enolase 3
chr6_+_106086316 1.48 ENST00000369091.6
ENST00000369096.9
PR/SET domain 1
chr3_+_48465811 1.42 ENST00000433541.1
ENST00000444177.1
three prime repair exonuclease 1
chr16_+_30199860 1.39 ENST00000395138.6
sulfotransferase family 1A member 3
chr6_-_83431038 1.38 ENST00000369705.4
malic enzyme 1
chr12_-_76423256 1.37 ENST00000546946.5
oxysterol binding protein like 8
chr2_+_74530018 1.32 ENST00000437202.1
HtrA serine peptidase 2
chr2_+_68974573 1.32 ENST00000673932.3
ENST00000377938.4
gastrokine 1
chr1_+_156114700 1.28 ENST00000677389.1
ENST00000368300.9
ENST00000368299.7
lamin A/C
chr17_-_41140487 1.25 ENST00000345847.4
keratin associated protein 4-6
chr9_+_135561749 1.25 ENST00000479141.6
ENST00000611414.4
ENST00000371766.6
ENST00000277508.9
ENST00000433563.5
progestagen associated endometrial protein
chr12_-_130716264 1.23 ENST00000643940.1
RIMS binding protein 2
chr4_+_168092530 1.18 ENST00000359299.8
annexin A10
chr7_+_134843884 1.16 ENST00000445569.6
caldesmon 1
chr12_-_70788914 1.15 ENST00000342084.8
protein tyrosine phosphatase receptor type R
chr22_+_20507571 1.12 ENST00000414658.5
ENST00000432052.5
ENST00000292733.11
ENST00000263205.11
ENST00000406969.5
mediator complex subunit 15
chr10_-_30999469 1.11 ENST00000538351.6
zinc finger protein 438
chr15_-_48963912 1.10 ENST00000332408.9
SHC adaptor protein 4
chr6_+_10521337 1.09 ENST00000495262.7
glucosaminyl (N-acetyl) transferase 2 (I blood group)
chr15_+_86079863 1.07 ENST00000614907.3
ENST00000441037.7
ATP/GTP binding protein like 1
chr5_+_179820895 1.07 ENST00000504627.1
ENST00000389805.9
ENST00000510187.5
sequestosome 1
chr10_-_118754956 1.06 ENST00000369151.8
CDK2 associated cullin domain 1
chr1_+_156114251 1.06 ENST00000361308.9
lamin A/C
chr15_-_22980334 1.06 ENST00000610365.4
ENST00000617928.5
ENST00000611832.4
cytoplasmic FMR1 interacting protein 1
chr3_-_11568764 1.05 ENST00000424529.6
vestigial like family member 4
chr16_-_31150058 1.05 ENST00000569305.1
ENST00000268281.9
ENST00000418068.6
serine protease 36
chr22_+_39520553 1.05 ENST00000674920.3
ENST00000679776.1
ENST00000675582.2
ENST00000337304.2
ENST00000676346.2
ENST00000396680.3
ENST00000680446.1
ENST00000674568.2
ENST00000680748.1
ENST00000674835.2
activating transcription factor 4
chr5_-_150113344 1.04 ENST00000286301.7
ENST00000511344.1
colony stimulating factor 1 receptor
chrX_-_49043345 1.01 ENST00000315869.8
transcription factor binding to IGHM enhancer 3
chr11_-_133845495 1.00 ENST00000299140.8
ENST00000532889.1
spermatogenesis associated 19
chr16_-_28597042 0.99 ENST00000533150.5
ENST00000335715.9
sulfotransferase family 1A member 2
chr1_+_152908538 0.96 ENST00000368764.4
involucrin
chrX_+_154542194 0.94 ENST00000618670.4
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
chrX_+_41333905 0.92 ENST00000457138.7
ENST00000643821.1
DEAD-box helicase 3 X-linked
chr2_-_179746040 0.91 ENST00000409343.5
zinc finger protein 385B
chr9_-_120877026 0.84 ENST00000436309.5
PHD finger protein 19
chr2_+_232697362 0.82 ENST00000482666.5
ENST00000483164.5
ENST00000490229.5
ENST00000464805.5
ENST00000489328.1
GRB10 interacting GYF protein 2
chr10_+_119651372 0.79 ENST00000369085.8
BAG cochaperone 3
chr1_+_15617415 0.78 ENST00000480945.6
DNA damage inducible 1 homolog 2
chr1_+_36155930 0.73 ENST00000316156.8
MAP7 domain containing 1
chr3_+_98353854 0.70 ENST00000354924.2
olfactory receptor family 5 subfamily K member 4
chr1_+_156126525 0.70 ENST00000504687.6
ENST00000473598.6
lamin A/C
chr19_-_35501878 0.68 ENST00000593342.5
ENST00000601650.1
ENST00000408915.6
dermokine
chr1_+_36156096 0.67 ENST00000474796.2
ENST00000373150.8
ENST00000373151.6
MAP7 domain containing 1
chr14_+_21918161 0.63 ENST00000390439.2
T cell receptor alpha variable 13-2
chr20_+_32358303 0.60 ENST00000651418.1
ENST00000375687.10
ENST00000542461.5
ENST00000613218.4
ENST00000646367.1
ENST00000620121.4
ASXL transcriptional regulator 1
chr17_-_40755328 0.60 ENST00000312150.5
keratin 25
chr3_+_156142962 0.59 ENST00000471742.5
potassium voltage-gated channel subfamily A member regulatory beta subunit 1
chr17_-_35433250 0.59 ENST00000452764.3
schlafen family member 12
chr11_-_57649894 0.57 ENST00000534810.3
ENST00000300022.8
yippee like 4
chr2_+_165469647 0.57 ENST00000421875.5
ENST00000314499.11
ENST00000409664.5
ENST00000651982.1
cysteine and serine rich nuclear protein 3
chr2_-_223602284 0.56 ENST00000421386.1
ENST00000305409.3
ENST00000433889.1
secretogranin II
chr3_-_49358320 0.55 ENST00000643797.1
ENST00000646881.2
ENST00000496791.2
glutathione peroxidase 1
chr3_-_49358272 0.55 ENST00000419349.2
glutathione peroxidase 1
chr1_-_112704921 0.52 ENST00000414971.1
ENST00000534717.5
ras homolog family member C
chr4_+_174918355 0.49 ENST00000505141.5
ENST00000359240.7
ENST00000615367.4
ENST00000445694.5
ENST00000618444.1
ADAM metallopeptidase domain 29
chr9_-_120876356 0.49 ENST00000456291.1
PHD finger protein 19
chr1_-_166975407 0.47 ENST00000528703.5
ENST00000525740.5
ENST00000529387.5
ENST00000469934.6
ENST00000529071.5
ENST00000526687.1
ENST00000271417.8
immunoglobulin like domain containing receptor 2
chr11_-_57649932 0.47 ENST00000524669.5
yippee like 4
chr3_-_9878488 0.46 ENST00000443115.1
cell death inducing DFFA like effector c
chr4_+_174918400 0.45 ENST00000404450.8
ENST00000514159.1
ADAM metallopeptidase domain 29
chr9_-_23826299 0.42 ENST00000380117.5
ELAV like RNA binding protein 2
chrX_-_71106728 0.42 ENST00000374251.6
chromosome X open reading frame 65
chr6_+_125219804 0.42 ENST00000524679.1
TPD52 like 1
chr19_+_3366549 0.41 ENST00000341919.7
ENST00000590282.5
ENST00000443272.3
nuclear factor I C
chr3_+_191329342 0.41 ENST00000392455.9
coiled-coil domain containing 50
chr7_-_122702912 0.41 ENST00000447240.1
ENST00000434824.2
ring finger protein 148
chr16_+_89921851 0.39 ENST00000554444.5
ENST00000556565.5
tubulin beta 3 class III
chr19_-_45782388 0.39 ENST00000458663.6
DM1 protein kinase
chr12_+_53098846 0.39 ENST00000650247.1
ENST00000549628.1
insulin like growth factor binding protein 6
chrX_+_47193796 0.37 ENST00000442035.5
ENST00000335972.11
ENST00000457753.5
ubiquitin like modifier activating enzyme 1
chr7_-_151024423 0.37 ENST00000469530.4
ENST00000639579.1
autophagy related 9B
chr16_-_53052849 0.37 ENST00000619363.2
novel protein
chr3_+_191329020 0.36 ENST00000392456.4
coiled-coil domain containing 50
chr4_-_99435134 0.35 ENST00000476959.5
ENST00000482593.5
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr17_-_49210567 0.34 ENST00000507680.6
G protein subunit gamma transducin 2
chr3_-_48595267 0.33 ENST00000328333.12
ENST00000681320.1
collagen type VII alpha 1 chain
chr10_-_88851809 0.33 ENST00000371930.5
ankyrin repeat domain 22
chr1_-_160579439 0.32 ENST00000368054.8
ENST00000368048.7
ENST00000311224.8
ENST00000368051.3
ENST00000534968.5
CD84 molecule
chr12_-_119804298 0.32 ENST00000678652.1
ENST00000678494.1
citron rho-interacting serine/threonine kinase
chr7_+_148133684 0.32 ENST00000628930.2
contactin associated protein 2
chr11_-_111379268 0.31 ENST00000393067.8
POU class 2 homeobox associating factor 1
chrY_+_12904860 0.31 ENST00000336079.8
DEAD-box helicase 3 Y-linked
chr10_+_87095169 0.31 ENST00000298784.5
ENST00000298786.5
shieldin complex subunit 2
chr14_+_103334339 0.30 ENST00000558316.5
ENST00000558265.5
eukaryotic translation initiation factor 5
chr18_+_2846974 0.30 ENST00000254528.4
elastin microfibril interfacer 2
chr5_+_145937793 0.29 ENST00000511217.1
SH3 domain containing ring finger 2
chr12_-_119804472 0.28 ENST00000678087.1
ENST00000677993.1
citron rho-interacting serine/threonine kinase
chr2_-_99254281 0.26 ENST00000409238.5
ENST00000423800.5
lysozyme g2
chr2_+_46698909 0.25 ENST00000650611.1
ENST00000306503.5
long intergenic non-protein coding RNA 1118
suppressor of cytokine signaling 5
chr8_-_81483226 0.24 ENST00000256104.5
fatty acid binding protein 4
chr9_-_107489754 0.24 ENST00000610832.1
ENST00000374672.5
Kruppel like factor 4
chr17_-_1649854 0.23 ENST00000301336.7
Rab interacting lysosomal protein
chr17_-_49708145 0.23 ENST00000514907.5
ENST00000503334.5
ENST00000508520.5
solute carrier family 35 member B1
chr11_-_66336396 0.22 ENST00000627248.1
ENST00000311320.9
Ras and Rab interactor 1
chr16_+_28985095 0.22 ENST00000454369.6
linker for activation of T cells
chr11_-_102955705 0.22 ENST00000615555.4
ENST00000340273.4
ENST00000260302.8
matrix metallopeptidase 13
chr2_-_144517663 0.21 ENST00000427902.5
ENST00000462355.2
ENST00000470879.5
ENST00000409487.7
ENST00000435831.5
ENST00000630572.2
zinc finger E-box binding homeobox 2
chr16_+_28985043 0.21 ENST00000395456.7
ENST00000564277.5
ENST00000630764.2
ENST00000354453.7
linker for activation of T cells
chr7_+_23246697 0.20 ENST00000381990.6
ENST00000409458.3
ENST00000647578.1
ENST00000258733.9
glycoprotein nmb
chr10_-_114174183 0.20 ENST00000369285.7
ENST00000369287.8
ENST00000369286.1
ENST00000648613.1
coiled-coil domain containing 186
chr15_-_53733103 0.20 ENST00000559418.5
WD repeat domain 72
chr1_-_107688492 0.19 ENST00000415432.6
vav guanine nucleotide exchange factor 3
chrX_-_154019800 0.19 ENST00000444230.5
ENST00000393687.6
ENST00000429936.6
ENST00000369974.6
ENST00000369980.8
interleukin 1 receptor associated kinase 1
chr20_+_49812818 0.19 ENST00000361573.3
solute carrier family 9 member A8
chr2_-_219308963 0.19 ENST00000423636.6
ENST00000442029.5
ENST00000412847.5
protein tyrosine phosphatase receptor type N
chr13_-_41019289 0.19 ENST00000239882.7
E74 like ETS transcription factor 1
chr6_-_49787265 0.18 ENST00000304801.6
phosphoglycerate kinase 2
chr2_+_219627565 0.18 ENST00000273063.10
solute carrier family 4 member 3
chr16_+_14186707 0.18 ENST00000572567.5
myocardin related transcription factor B
chr1_-_110606009 0.17 ENST00000640774.2
ENST00000638616.2
potassium voltage-gated channel subfamily A member 2
chr3_+_138434609 0.17 ENST00000389567.9
ENST00000289135.4
extended synaptotagmin 3
chr5_+_146203544 0.16 ENST00000506502.2
novel readthrough transcript
chr14_+_73058521 0.16 ENST00000527432.5
ENST00000531500.5
ENST00000261973.12
ENST00000525321.5
ENST00000526754.5
RNA binding motif protein 25
chr8_-_70071226 0.16 ENST00000276594.3
PR/SET domain 14
chr20_+_49812697 0.16 ENST00000417961.5
solute carrier family 9 member A8
chr2_+_219627650 0.16 ENST00000317151.7
solute carrier family 4 member 3
chr12_-_57478070 0.14 ENST00000549602.1
ENST00000430041.6
Rho GTPase activating protein 9
chr11_-_102874974 0.14 ENST00000571244.3
matrix metallopeptidase 12
chr3_-_45915698 0.13 ENST00000539217.5
leucine zipper transcription factor like 1
chr12_-_57520480 0.13 ENST00000642841.1
ENST00000547303.5
ENST00000552740.5
ENST00000547526.1
ENST00000346473.8
ENST00000551116.5
novel protein
DNA damage inducible transcript 3
chr2_+_219627394 0.12 ENST00000373760.6
solute carrier family 4 member 3
chr2_+_219627622 0.12 ENST00000358055.8
solute carrier family 4 member 3
chrX_+_134237047 0.11 ENST00000370809.4
ENST00000517294.5
coiled-coil domain containing 160
chrX_+_57592011 0.11 ENST00000374888.3
zinc finger X-linked duplicated B
chr19_-_51368979 0.10 ENST00000601435.1
ENST00000291715.5
claudin domain containing 2
chr6_+_56955097 0.10 ENST00000370746.8
ENST00000370748.7
BEN domain containing 6
chr17_+_57085092 0.09 ENST00000575322.1
ENST00000337714.8
A-kinase anchoring protein 1
chr12_+_113422354 0.09 ENST00000403593.9
ENST00000553248.5
ENST00000345635.8
ENST00000547802.1
serine dehydratase like
chr12_+_100473951 0.09 ENST00000648861.1
ENST00000546380.1
nuclear receptor subfamily 1 group H member 4
chr2_-_152098810 0.08 ENST00000636442.1
ENST00000638005.1
calcium voltage-gated channel auxiliary subunit beta 4
chr19_-_51034840 0.08 ENST00000529888.5
kallikrein related peptidase 12
chr19_-_51034993 0.08 ENST00000684732.1
kallikrein related peptidase 12
chr19_+_13731744 0.07 ENST00000586600.5
coiled-coil domain containing 130
chr16_+_30065777 0.07 ENST00000395240.7
ENST00000566846.5
aldolase, fructose-bisphosphate A
chr16_+_30065753 0.07 ENST00000642816.3
ENST00000643777.4
ENST00000569798.5
aldolase, fructose-bisphosphate A
chr10_+_125973373 0.07 ENST00000417114.5
ENST00000445510.5
ENST00000368691.5
fibronectin type III and ankyrin repeat domains 1
chr19_-_51034892 0.07 ENST00000319590.8
ENST00000250351.4
kallikrein related peptidase 12
chr3_+_19947316 0.06 ENST00000422242.1
RAB5A, member RAS oncogene family
chr1_+_26280117 0.06 ENST00000319041.6
SH3 domain binding glutamate rich protein like 3
chr1_+_151254709 0.06 ENST00000368881.8
ENST00000368884.8
proteasome 26S subunit, non-ATPase 4
chr6_-_31736504 0.05 ENST00000616760.1
ENST00000375784.7
ENST00000375779.6
chloride intracellular channel 1
chr4_-_99435336 0.05 ENST00000437033.7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr17_+_49210699 0.04 ENST00000225941.6
ABI family member 3
chr8_-_42768781 0.03 ENST00000276410.7
cholinergic receptor nicotinic alpha 6 subunit
chr3_-_9878765 0.03 ENST00000430427.6
ENST00000383817.5
ENST00000679265.1
cell death inducing DFFA like effector c
chr14_+_73058591 0.03 ENST00000525161.5
RNA binding motif protein 25
chr2_+_232697299 0.03 ENST00000476995.5
ENST00000427233.5
ENST00000629305.2
ENST00000428883.5
ENST00000456491.5
ENST00000409480.5
ENST00000492910.5
ENST00000464402.5
ENST00000490612.5
ENST00000475359.6
ENST00000421433.5
ENST00000425040.5
ENST00000430720.5
ENST00000409547.5
ENST00000373563.9
ENST00000423659.5
ENST00000409196.7
ENST00000488734.5
ENST00000409451.7
ENST00000429187.5
ENST00000440945.5
GRB10 interacting GYF protein 2
chr6_+_63211446 0.02 ENST00000370659.1
FKBP prolyl isomerase family member 1C
chr11_+_59107228 0.01 ENST00000529618.5
ENST00000534403.5
ENST00000343597.4
FAM111 trypsin like peptidase B
chr8_-_109975757 0.01 ENST00000524391.6
potassium voltage-gated channel modifier subfamily V member 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
8.8 35.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.9 2.8 GO:0046521 sphingoid catabolic process(GO:0046521)
0.8 3.2 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.8 2.3 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.7 2.9 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.7 2.8 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.6 6.4 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.6 6.1 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.5 4.7 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.5 3.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.5 1.5 GO:1990654 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.5 7.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.4 5.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.4 1.2 GO:1902490 regulation of sperm capacitation(GO:1902490)
0.4 8.3 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.4 1.1 GO:1902905 positive regulation of fibril organization(GO:1902905)
0.4 1.1 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.3 1.0 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.3 2.4 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.3 7.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.3 9.3 GO:0030728 ovulation(GO:0030728)
0.3 4.0 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.2 1.0 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.2 0.2 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.2 1.4 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.2 1.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.2 1.7 GO:0002051 osteoblast fate commitment(GO:0002051)
0.2 1.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.2 1.4 GO:0006741 NADP biosynthetic process(GO:0006741) regulation of NADP metabolic process(GO:1902031)
0.2 0.7 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 7.4 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.1 1.5 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 1.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 6.5 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 1.3 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 2.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 0.6 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 1.4 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 1.0 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.1 0.4 GO:0044805 late nucleophagy(GO:0044805)
0.1 1.7 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.1 0.7 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.1 0.2 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.1 0.2 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.1 0.3 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.3 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.1 0.3 GO:0071109 superior temporal gyrus development(GO:0071109)
0.1 1.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.2 GO:1904692 positive regulation of type B pancreatic cell proliferation(GO:1904692)
0.1 3.8 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 3.5 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.1 1.0 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 0.2 GO:0030718 inner cell mass cell fate commitment(GO:0001827) germ-line stem cell population maintenance(GO:0030718)
0.1 3.1 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 3.0 GO:0006298 mismatch repair(GO:0006298)
0.0 0.1 GO:1903565 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.6 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.6 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.3 GO:0045629 positive regulation of T-helper 1 cell differentiation(GO:0045627) negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.3 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.8 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 1.5 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.4 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.2 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 1.0 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.4 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 2.7 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.9 GO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423)
0.0 0.5 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.1 GO:0072641 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.2 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.2 GO:0021633 optic nerve structural organization(GO:0021633)
0.0 0.6 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 1.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 1.0 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.4 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.2 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.9 7.3 GO:0097451 glial limiting end-foot(GO:0097451)
0.8 3.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.6 7.7 GO:0043256 laminin complex(GO:0043256)
0.6 1.7 GO:0033565 ESCRT-0 complex(GO:0033565)
0.4 35.2 GO:0015030 Cajal body(GO:0015030)
0.4 1.1 GO:0044753 amphisome(GO:0044753)
0.3 1.0 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.3 3.1 GO:0005638 lamin filament(GO:0005638)
0.2 1.4 GO:1990635 proximal dendrite(GO:1990635)
0.2 1.0 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.2 2.8 GO:0035631 CD40 receptor complex(GO:0035631)
0.2 0.6 GO:0035517 PR-DUB complex(GO:0035517)
0.1 1.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.5 GO:0042587 glycogen granule(GO:0042587)
0.1 1.1 GO:0044294 dendritic growth cone(GO:0044294)
0.1 1.1 GO:0097413 Lewy body(GO:0097413)
0.1 8.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 1.2 GO:0030478 actin cap(GO:0030478)
0.1 0.9 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 5.2 GO:0005771 multivesicular body(GO:0005771)
0.1 0.3 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 1.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.8 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.5 GO:0033010 paranodal junction(GO:0033010)
0.0 0.6 GO:0031045 dense core granule(GO:0031045)
0.0 1.1 GO:0016592 mediator complex(GO:0016592)
0.0 10.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.0 GO:0001533 cornified envelope(GO:0001533)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 20.7 GO:0005730 nucleolus(GO:0005730)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 3.2 GO:0043209 myelin sheath(GO:0043209)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
11.7 35.2 GO:0008859 exoribonuclease II activity(GO:0008859)
1.3 6.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.6 6.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.4 3.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.4 2.8 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.4 8.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.3 1.0 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.3 1.4 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.3 1.5 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.3 1.4 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.2 9.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 5.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.2 3.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 0.7 GO:0043273 CTPase activity(GO:0043273)
0.2 1.0 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.2 1.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 1.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 6.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 9.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 1.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.3 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 1.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 4.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 0.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.2 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.1 0.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 2.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 7.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 1.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 1.2 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.3 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 1.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 1.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.7 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 5.3 GO:0008201 heparin binding(GO:0008201)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.6 GO:0070402 NADPH binding(GO:0070402)
0.0 3.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.6 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.6 GO:0042056 chemoattractant activity(GO:0042056)
0.0 4.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 4.0 GO:0003823 antigen binding(GO:0003823)
0.0 0.5 GO:0005549 odorant binding(GO:0005549)
0.0 1.2 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.9 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 13.4 GO:0005509 calcium ion binding(GO:0005509)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 7.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 9.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 2.9 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 5.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 3.9 ST GAQ PATHWAY G alpha q Pathway
0.1 6.4 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 1.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 6.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 6.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 3.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 2.4 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 18.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 10.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.0 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 3.6 PID P73PATHWAY p73 transcription factor network
0.0 1.7 PID FGF PATHWAY FGF signaling pathway
0.0 1.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 2.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 35.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.3 4.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 8.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.2 3.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 1.3 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 4.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 2.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 5.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 2.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 2.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 1.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.7 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 7.7 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 3.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 7.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 2.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.4 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels