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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for KLF1

Z-value: 0.63

Motif logo

Transcription factors associated with KLF1

Gene Symbol Gene ID Gene Info
ENSG00000105610.6 KLF1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF1hg38_v1_chr19_-_12887188_128872070.537.0e-03Click!

Activity profile of KLF1 motif

Sorted Z-values of KLF1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_120100688 1.31 ENST00000652264.1
notch receptor 2
chrX_-_72306891 1.12 ENST00000454225.1
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1
chr5_-_132490750 1.04 ENST00000437654.6
ENST00000245414.9
ENST00000680139.1
ENST00000680352.1
ENST00000679440.1
ENST00000680903.1
interferon regulatory factor 1
chr17_+_7307579 0.97 ENST00000572815.5
eukaryotic translation initiation factor 5A
chr1_-_1214146 0.92 ENST00000379236.4
TNF receptor superfamily member 4
chr19_+_8052335 0.91 ENST00000680507.1
ENST00000680450.1
ENST00000681526.1
ENST00000680506.1
C-C motif chemokine ligand 25
chr19_+_8052752 0.87 ENST00000315626.6
ENST00000253451.9
C-C motif chemokine ligand 25
chr16_-_31150058 0.83 ENST00000569305.1
ENST00000268281.9
ENST00000418068.6
serine protease 36
chr20_+_6767678 0.82 ENST00000378827.5
bone morphogenetic protein 2
chr11_+_19712823 0.77 ENST00000396085.6
ENST00000349880.9
neuron navigator 2
chr19_+_8053000 0.74 ENST00000390669.7
C-C motif chemokine ligand 25
chr15_+_90388234 0.74 ENST00000268182.10
ENST00000560738.1
ENST00000560418.1
IQ motif containing GTPase activating protein 1
chr19_+_8052315 0.72 ENST00000680646.1
C-C motif chemokine ligand 25
chr6_-_3227643 0.70 ENST00000259818.8
tubulin beta 2B class IIb
chr2_-_37671633 0.69 ENST00000295324.4
CDC42 effector protein 3
chr7_+_134745460 0.67 ENST00000436461.6
caldesmon 1
chr1_-_94541746 0.67 ENST00000334047.12
coagulation factor III, tissue factor
chr6_-_81752671 0.60 ENST00000320172.11
ENST00000369754.7
ENST00000369756.3
terminal nucleotidyltransferase 5A
chr6_-_43629222 0.59 ENST00000307126.10
GTP binding protein 2
chr10_+_94683771 0.57 ENST00000339022.6
cytochrome P450 family 2 subfamily C member 18
chr14_+_23376765 0.57 ENST00000649278.1
CKLF like MARVEL transmembrane domain containing 5
chr12_-_57110284 0.56 ENST00000543873.6
ENST00000554663.5
ENST00000557635.5
signal transducer and activator of transcription 6
chr20_-_20712626 0.55 ENST00000202677.12
Ral GTPase activating protein catalytic subunit alpha 2
chr6_+_106098933 0.55 ENST00000369089.3
PR/SET domain 1
chr18_-_51197671 0.51 ENST00000406189.4
mex-3 RNA binding family member C
chr17_-_41350824 0.50 ENST00000007735.4
keratin 33A
chr8_+_122781621 0.49 ENST00000314393.6
zinc fingers and homeoboxes 2
chr16_+_50742110 0.49 ENST00000566679.6
ENST00000564634.5
ENST00000398568.6
CYLD lysine 63 deubiquitinase
chr16_+_50742037 0.49 ENST00000569418.5
CYLD lysine 63 deubiquitinase
chr16_-_11586941 0.48 ENST00000571976.1
ENST00000413364.6
lipopolysaccharide induced TNF factor
chr3_-_186362223 0.47 ENST00000265022.8
diacylglycerol kinase gamma
chr1_-_159923717 0.46 ENST00000368096.5
transgelin 2
chr17_+_7307602 0.46 ENST00000573542.5
ENST00000336458.13
eukaryotic translation initiation factor 5A
chr8_-_100950549 0.46 ENST00000395951.7
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
chr12_-_89524734 0.45 ENST00000529983.3
polypeptide N-acetylgalactosaminyltransferase 4
chr5_-_95961830 0.44 ENST00000513343.1
ENST00000237853.9
elongation factor for RNA polymerase II 2
chr3_+_50236192 0.44 ENST00000313601.11
G protein subunit alpha i2
chr15_+_99565950 0.44 ENST00000557785.5
ENST00000558049.5
ENST00000449277.6
myocyte enhancer factor 2A
chr5_+_173888335 0.43 ENST00000265085.10
cytoplasmic polyadenylation element binding protein 4
chr1_-_27490045 0.43 ENST00000536657.1
WASP family member 2
chr14_+_23376786 0.42 ENST00000359320.7
CKLF like MARVEL transmembrane domain containing 5
chr14_+_41608344 0.42 ENST00000554120.5
leucine rich repeat and fibronectin type III domain containing 5
chr15_+_99565921 0.42 ENST00000558812.5
ENST00000338042.10
myocyte enhancer factor 2A
chr22_+_37675629 0.42 ENST00000215909.10
galectin 1
chr22_+_37906275 0.42 ENST00000215957.10
ENST00000445494.6
ENST00000680578.1
ENST00000424008.2
MICAL like 1
chr14_+_23377001 0.42 ENST00000342473.8
ENST00000397227.7
ENST00000339180.9
ENST00000555731.5
CKLF like MARVEL transmembrane domain containing 5
chr16_+_50742059 0.41 ENST00000311559.13
ENST00000564326.5
ENST00000566206.5
ENST00000427738.8
CYLD lysine 63 deubiquitinase
chr1_-_111200633 0.41 ENST00000357640.9
DENN domain containing 2D
chr19_-_35908247 0.40 ENST00000585901.6
ENST00000544690.6
ENST00000424586.7
ENST00000262629.9
ENST00000589517.1
transmembrane immune signaling adaptor TYROBP
chr11_+_66616606 0.40 ENST00000393979.3
ENST00000409372.1
ENST00000310137.5
ENST00000443702.1
ENST00000409738.4
ENST00000412278.2
ENST00000500635.2
RNA binding motif protein 14
RBM14-RBM4 readthrough
chr16_-_4416621 0.38 ENST00000570645.5
ENST00000574025.5
ENST00000572898.1
ENST00000537233.6
ENST00000571059.5
coronin 7
chrX_+_154458274 0.37 ENST00000369682.4
plexin A3
chr12_+_116559381 0.37 ENST00000556529.4
microtubule associated protein 1 light chain 3 beta 2
chr17_+_82031643 0.37 ENST00000306897.9
Rac family small GTPase 3
chr7_-_80919017 0.37 ENST00000265361.8
semaphorin 3C
chr1_-_12616762 0.37 ENST00000464917.5
dehydrogenase/reductase 3
chr5_+_103258747 0.36 ENST00000319933.7
macrophage immunometabolism regulator
chr17_-_41369807 0.36 ENST00000251646.8
keratin 33B
chr1_-_160343235 0.36 ENST00000368069.7
ENST00000241704.8
ENST00000647683.1
ENST00000649787.1
COPI coat complex subunit alpha
chr19_+_8390316 0.35 ENST00000328024.11
ENST00000601897.1
ENST00000594216.1
RAB11B, member RAS oncogene family
chr16_+_30664334 0.35 ENST00000287468.5
fibrosin
chr17_+_7307531 0.35 ENST00000576930.5
eukaryotic translation initiation factor 5A
chr19_+_35138993 0.35 ENST00000612146.4
ENST00000589209.5
FXYD domain containing ion transport regulator 1
chr1_-_243163310 0.35 ENST00000492145.1
ENST00000490813.5
ENST00000464936.5
centrosomal protein 170
chr10_+_132537814 0.35 ENST00000368593.7
inositol polyphosphate-5-phosphatase A
chr17_-_2711633 0.34 ENST00000435359.5
clustered mitochondria homolog
chr12_-_129904017 0.34 ENST00000422113.7
transmembrane protein 132D
chr2_+_72916183 0.34 ENST00000394111.6
empty spiracles homeobox 1
chr2_-_152717451 0.34 ENST00000545856.7
ENST00000493468.7
ENST00000448428.2
pre-mRNA processing factor 40 homolog A
chr6_-_30687200 0.33 ENST00000399199.7
protein phosphatase 1 regulatory subunit 18
chr6_-_38639852 0.33 ENST00000498633.1
ENST00000649492.1
BTB domain containing 9
chr1_+_18107763 0.33 ENST00000251296.4
immunoglobin superfamily member 21
chr5_-_116574802 0.32 ENST00000343348.11
semaphorin 6A
chr8_-_27258414 0.32 ENST00000523048.5
stathmin 4
chr7_-_140062841 0.32 ENST00000263549.8
poly(ADP-ribose) polymerase family member 12
chrX_-_72306962 0.32 ENST00000246139.9
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1
chr1_-_27490130 0.31 ENST00000618852.5
WASP family member 2
chr17_-_7238171 0.31 ENST00000574236.5
ENST00000572789.5
PHD finger protein 23
chr9_-_34048868 0.31 ENST00000379239.9
ENST00000684158.1
ENST00000379238.7
ENST00000360802.6
ubiquitin associated protein 2
chr11_-_65662780 0.31 ENST00000534283.1
ENST00000527749.5
ENST00000533187.5
ENST00000525693.5
ENST00000534558.5
ENST00000532879.5
ENST00000406246.8
ENST00000532999.5
RELA proto-oncogene, NF-kB subunit
chr8_+_119416427 0.31 ENST00000259526.4
cellular communication network factor 3
chr4_-_10116324 0.31 ENST00000508079.1
WD repeat domain 1
chr19_+_46347063 0.31 ENST00000012443.9
ENST00000391919.1
protein phosphatase 5 catalytic subunit
chr11_-_65857543 0.30 ENST00000534784.1
cofilin 1
chr3_+_49412203 0.30 ENST00000273590.3
T cell leukemia translocation altered
chr12_-_49187369 0.30 ENST00000547939.6
tubulin alpha 1a
chr22_-_30246739 0.30 ENST00000403987.3
ENST00000249075.4
LIF interleukin 6 family cytokine
chr22_-_38088915 0.29 ENST00000428572.1
BAR/IMD domain containing adaptor protein 2 like 2
chr5_+_103259400 0.29 ENST00000510890.1
macrophage immunometabolism regulator
chr7_-_139109702 0.29 ENST00000471652.1
ENST00000242351.10
zinc finger CCCH-type containing, antiviral 1
chr3_-_49411917 0.29 ENST00000454011.7
ENST00000445425.6
ENST00000422781.6
ENST00000418115.6
ENST00000678921.2
ENST00000676712.2
ras homolog family member A
chr19_+_35629107 0.29 ENST00000589871.1
RNA binding motif protein 42
chr10_-_102241502 0.29 ENST00000370002.8
paired like homeodomain 3
chrX_-_72307148 0.28 ENST00000453707.6
ENST00000373619.7
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1
chr15_-_48645701 0.28 ENST00000316623.10
ENST00000560355.1
fibrillin 1
chr17_-_51120734 0.28 ENST00000505279.5
sperm associated antigen 9
chr10_+_119207560 0.28 ENST00000392870.3
G protein-coupled receptor kinase 5
chr19_+_7920313 0.27 ENST00000221573.11
ENST00000595637.1
small nuclear RNA activating complex polypeptide 2
chr7_+_86644829 0.27 ENST00000439827.1
ENST00000421579.1
glutamate metabotropic receptor 3
chr10_-_77637902 0.27 ENST00000286627.10
ENST00000639486.1
ENST00000640523.1
potassium calcium-activated channel subfamily M alpha 1
chr3_-_197298092 0.27 ENST00000392382.6
discs large MAGUK scaffold protein 1
chr2_-_196593544 0.27 ENST00000644978.2
ENST00000427457.2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr11_+_64241600 0.27 ENST00000535135.7
ENST00000652094.1
FKBP prolyl isomerase 2
chr9_-_129028185 0.27 ENST00000417224.5
ENST00000416629.5
ENST00000372559.5
SH3 domain containing GRB2 like, endophilin B2
chr6_-_30742203 0.27 ENST00000416018.5
ENST00000445853.5
ENST00000413165.5
ENST00000418160.5
flotillin 1
chr11_-_65857763 0.27 ENST00000531407.5
cofilin 1
chr12_-_48971723 0.26 ENST00000301061.9
Wnt family member 10B
chr17_+_32487686 0.26 ENST00000584792.5
cyclin dependent kinase 5 regulatory subunit 1
chrX_-_23743201 0.26 ENST00000492081.1
ENST00000379303.10
ENST00000336430.11
acyl-CoA thioesterase 9
chr5_+_71719267 0.26 ENST00000296777.5
CART prepropeptide
chr17_-_44199834 0.26 ENST00000587097.6
ataxin 7 like 3
chr14_-_64942783 0.26 ENST00000612794.1
glutathione peroxidase 2
chr2_+_219514477 0.25 ENST00000347842.8
ENST00000358078.5
acid sensing ion channel subunit family member 4
chr2_+_207711534 0.25 ENST00000392209.7
cyclin Y like 1
chr6_-_39314412 0.25 ENST00000373231.9
potassium two pore domain channel subfamily K member 17
chr7_+_74658004 0.25 ENST00000443166.5
general transcription factor IIi
chr1_-_222712428 0.25 ENST00000355727.3
ENST00000340020.11
axin interactor, dorsalization associated
chr8_+_80485641 0.25 ENST00000430430.5
zinc finger and BTB domain containing 10
chr8_+_80486209 0.25 ENST00000426744.5
ENST00000455036.8
zinc finger and BTB domain containing 10
chr11_-_62754141 0.25 ENST00000527994.1
ENST00000394807.5
ENST00000673933.1
zinc finger and BTB domain containing 3
chr2_-_152717966 0.25 ENST00000410080.8
pre-mRNA processing factor 40 homolog A
chr15_-_89334794 0.24 ENST00000268124.11
ENST00000442287.6
DNA polymerase gamma, catalytic subunit
chr1_-_31239880 0.24 ENST00000373736.7
sodium/potassium transporting ATPase interacting 1
chr1_-_167914089 0.24 ENST00000476818.2
ENST00000367848.1
ENST00000367851.9
ENST00000545172.5
adenylate cyclase 10
chr10_+_31319125 0.24 ENST00000320985.14
ENST00000560721.6
ENST00000558440.5
ENST00000424869.6
ENST00000542815.7
zinc finger E-box binding homeobox 1
chr3_+_39051990 0.24 ENST00000302313.10
WD repeat domain 48
chr2_+_200306648 0.24 ENST00000409140.8
spermatogenesis associated serine rich 2 like
chr12_+_68610858 0.24 ENST00000393436.9
ENST00000425247.6
ENST00000250559.14
ENST00000489473.6
ENST00000422358.6
ENST00000541167.5
ENST00000538283.5
ENST00000341355.9
ENST00000537460.5
ENST00000450214.6
ENST00000545270.5
RAP1B, member of RAS oncogene family
chr10_+_31321152 0.24 ENST00000446923.7
zinc finger E-box binding homeobox 1
chr6_+_106086316 0.24 ENST00000369091.6
ENST00000369096.9
PR/SET domain 1
chr19_-_43504711 0.23 ENST00000601646.1
pleckstrin homology like domain family B member 3
chr16_+_31472130 0.23 ENST00000394863.8
ENST00000565360.5
ENST00000361773.7
transforming growth factor beta 1 induced transcript 1
chr19_-_43781249 0.23 ENST00000615047.4
potassium calcium-activated channel subfamily N member 4
chr6_-_138107412 0.23 ENST00000421351.4
p53 apoptosis effector related to PMP22
chr14_-_64942720 0.23 ENST00000557049.1
ENST00000389614.6
glutathione peroxidase 2
chr22_-_35961623 0.23 ENST00000408983.2
RNA binding fox-1 homolog 2
chr9_-_37465402 0.23 ENST00000307750.5
zinc finger and BTB domain containing 5
chr19_+_35775515 0.23 ENST00000378944.9
Rho GTPase activating protein 33
chr13_+_23979794 0.23 ENST00000424834.6
ENST00000439928.2
spermatogenesis associated 13
spermatogenesis associated 13
chr19_+_45178739 0.23 ENST00000433642.3
biogenesis of lysosomal organelles complex 1 subunit 3
chr1_+_28887166 0.23 ENST00000347529.7
erythrocyte membrane protein band 4.1
chr17_-_51120855 0.23 ENST00000618113.4
ENST00000357122.8
ENST00000262013.12
sperm associated antigen 9
chr16_-_4416564 0.23 ENST00000572467.5
ENST00000251166.9
ENST00000572044.1
ENST00000571052.5
CORO7-PAM16 readthrough
coronin 7
chr2_-_160062589 0.22 ENST00000392771.1
ENST00000283243.13
phospholipase A2 receptor 1
chr16_+_56191476 0.22 ENST00000262493.12
G protein subunit alpha o1
chr6_-_39314445 0.22 ENST00000453413.2
potassium two pore domain channel subfamily K member 17
chr11_-_57322197 0.22 ENST00000532437.1
tankyrase 1 binding protein 1
chr15_-_64356074 0.22 ENST00000634811.1
ENST00000303052.13
ENST00000607537.6
casein kinase 1 gamma 1
chr10_-_77637558 0.22 ENST00000372421.10
ENST00000639370.1
ENST00000640773.1
ENST00000638895.1
potassium calcium-activated channel subfamily M alpha 1
chrX_-_132489842 0.22 ENST00000436215.5
muscleblind like splicing regulator 3
chrX_-_48911634 0.22 ENST00000635460.1
ENST00000247138.11
ENST00000376529.8
ENST00000635589.1
ENST00000616181.5
ENST00000452555.7
ENST00000635238.1
ENST00000634665.1
ENST00000635015.1
ENST00000445167.7
ENST00000634461.1
ENST00000376512.2
solute carrier family 35 member A2
chr2_+_101697699 0.22 ENST00000350878.8
ENST00000350198.8
ENST00000324219.8
ENST00000425019.5
mitogen-activated protein kinase kinase kinase kinase 4
chr11_-_75668566 0.22 ENST00000526740.3
microtubule associated protein 6
chr10_+_80454274 0.22 ENST00000372158.6
ENST00000372157.6
ENST00000372164.7
ENST00000341863.10
tetraspanin 14
chr5_-_84384871 0.21 ENST00000296591.10
EGF like repeats and discoidin domains 3
chr2_-_61538516 0.21 ENST00000676771.1
ENST00000677814.1
ENST00000443240.5
ENST00000677556.1
ENST00000676553.1
exportin 1
chr16_+_89923333 0.21 ENST00000315491.12
ENST00000555576.5
ENST00000554336.5
ENST00000553967.1
tubulin beta 3 class III
chr9_-_35732122 0.21 ENST00000314888.10
talin 1
chr17_+_82032061 0.21 ENST00000580965.5
Rac family small GTPase 3
chr12_-_124914056 0.21 ENST00000541272.1
ENST00000535131.1
ubiquitin C
chr16_+_280572 0.21 ENST00000219409.8
Rho GDP dissociation inhibitor gamma
chr11_+_61481110 0.20 ENST00000338608.7
ENST00000432063.6
protein phosphatase 1 regulatory subunit 32
chr17_-_2711736 0.20 ENST00000651024.2
ENST00000576885.5
ENST00000574426.7
clustered mitochondria homolog
chr17_+_17972813 0.20 ENST00000582416.5
ENST00000313838.12
ENST00000399187.6
ENST00000581264.5
ENST00000479684.2
ENST00000584166.5
ENST00000585108.5
ENST00000399182.5
ENST00000579977.1
dynein regulatory complex subunit 3
chr1_+_47438036 0.20 ENST00000334793.6
forkhead box D2
chr3_+_42502592 0.20 ENST00000438259.6
ENST00000543411.5
ENST00000439731.5
ENST00000325123.5
vasoactive intestinal peptide receptor 1
chrX_-_48957871 0.20 ENST00000610466.4
OTU deubiquitinase 5
chr17_-_42388467 0.20 ENST00000678792.1
ENST00000679166.1
ENST00000677442.1
ENST00000677723.1
ENST00000678905.1
ENST00000677479.1
ENST00000678043.1
ENST00000677152.1
ENST00000677603.1
ENST00000588969.5
ENST00000678535.1
ENST00000679185.1
ENST00000677030.1
ENST00000679014.1
ENST00000678044.1
ENST00000678827.1
signal transducer and activator of transcription 3
chr12_-_53625971 0.20 ENST00000588078.5
ENST00000551480.2
ENST00000548118.6
ENST00000456903.8
ENST00000591834.1
activating transcription factor 7
ATF7-NPFF readthrough
chr5_-_116574395 0.20 ENST00000257414.12
semaphorin 6A
chr14_+_23555983 0.20 ENST00000404535.3
thiamine triphosphatase
chr17_-_41397600 0.20 ENST00000251645.3
keratin 31
chrX_+_56232343 0.20 ENST00000468660.6
Kruppel like factor 8
chr1_-_36385872 0.20 ENST00000373129.7
serine/threonine kinase 40
chr3_-_197297523 0.19 ENST00000434148.1
ENST00000412364.2
ENST00000661013.1
ENST00000666007.1
ENST00000422288.6
ENST00000456699.6
ENST00000392380.6
ENST00000670935.1
ENST00000656087.1
ENST00000436682.6
ENST00000662727.1
ENST00000670455.1
ENST00000659221.1
ENST00000671185.1
ENST00000669565.1
ENST00000660898.1
ENST00000667971.1
ENST00000661453.1
discs large MAGUK scaffold protein 1
chr1_-_36385887 0.19 ENST00000373130.7
ENST00000373132.4
serine/threonine kinase 40
chr6_+_30721573 0.19 ENST00000330914.7
tubulin beta class I
chr15_+_59438149 0.19 ENST00000288228.10
ENST00000559628.5
ENST00000557914.5
ENST00000560474.5
family with sequence similarity 81 member A
chr17_+_82032182 0.19 ENST00000584341.1
Rac family small GTPase 3
chr17_+_7306975 0.19 ENST00000336452.11
eukaryotic translation initiation factor 5A
chr8_-_143942524 0.19 ENST00000357649.6
plectin
chr12_-_99984629 0.19 ENST00000683438.1
ENST00000549866.5
ankyrin repeat and sterile alpha motif domain containing 1B
chr11_-_120138104 0.19 ENST00000341846.10
tripartite motif containing 29
chr16_+_56191728 0.18 ENST00000638705.1
ENST00000262494.12
G protein subunit alpha o1
chr2_-_24920155 0.18 ENST00000679454.1
adenylate cyclase 3
chr8_-_143943911 0.18 ENST00000354589.7
plectin
chr16_+_280448 0.18 ENST00000447871.5
Rho GDP dissociation inhibitor gamma
chr17_-_42388360 0.18 ENST00000678960.1
ENST00000404395.3
ENST00000389272.7
ENST00000677421.1
ENST00000585517.5
ENST00000264657.10
ENST00000678048.1
ENST00000678674.1
ENST00000678913.1
ENST00000678572.1
ENST00000678906.1
signal transducer and activator of transcription 3
chr12_-_57846686 0.18 ENST00000548823.1
ENST00000398073.7
CTD small phosphatase 2
chr5_-_16617085 0.18 ENST00000684521.1
reticulophagy regulator 1
chr20_-_4823597 0.17 ENST00000379400.8
Ras association domain family member 2
chr10_+_46375619 0.17 ENST00000584982.7
ENST00000613703.4
annexin A8 like 1
chr1_-_116667668 0.17 ENST00000369486.8
ENST00000369483.5
immunoglobulin superfamily member 3
chr11_+_67415670 0.17 ENST00000531040.5
ENST00000307823.7
carnosine synthase 1
chr18_+_58045642 0.17 ENST00000676223.1
ENST00000675147.1
NEDD4 like E3 ubiquitin protein ligase
chr6_-_114343012 0.17 ENST00000312719.10
heparan sulfate-glucosamine 3-sulfotransferase 5
chr5_+_150166790 0.17 ENST00000616154.1
caudal type homeobox 1
chr8_+_123416735 0.17 ENST00000524254.5
N-terminal glutamine amidase 1
chr19_+_35138778 0.17 ENST00000351325.9
ENST00000586871.5
ENST00000592174.1
FXYD domain containing ion transport regulator 1
novel transcript
chr1_+_11806096 0.17 ENST00000312413.10
ENST00000346436.11
chloride voltage-gated channel 6

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.2 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.3 1.4 GO:1990108 protein linear deubiquitination(GO:1990108)
0.3 1.7 GO:0071105 response to interleukin-11(GO:0071105)
0.3 0.8 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040) corticotropin hormone secreting cell differentiation(GO:0060128)
0.3 0.8 GO:1990654 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.3 1.0 GO:0035740 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.2 2.0 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.2 0.7 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1 0.6 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 0.8 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.1 0.4 GO:1902724 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.1 0.9 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.1 0.1 GO:1902823 negative regulation of late endosome to lysosome transport(GO:1902823)
0.1 0.4 GO:0071464 cellular response to hydrostatic pressure(GO:0071464)
0.1 0.1 GO:1904995 negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.1 0.3 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.1 0.7 GO:0071964 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.1 0.3 GO:0035498 carnosine metabolic process(GO:0035498)
0.1 0.3 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.1 0.4 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.1 0.4 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 0.4 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.6 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.3 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.1 0.5 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.1 0.4 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 1.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.3 GO:0042247 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.1 0.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.3 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.1 0.5 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.1 0.2 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.1 0.7 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.1 0.7 GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.1 0.2 GO:0006147 guanine catabolic process(GO:0006147)
0.1 0.2 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.1 0.4 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.1 0.2 GO:0008355 olfactory learning(GO:0008355)
0.1 0.5 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 0.3 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.2 GO:0021722 pons maturation(GO:0021586) superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.3 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.1 0.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.4 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.3 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.3 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 1.7 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.5 GO:0002934 desmosome organization(GO:0002934)
0.0 0.7 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.0 0.7 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.2 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.3 GO:0061709 reticulophagy(GO:0061709)
0.0 0.4 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.5 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.6 GO:1903764 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.1 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.3 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.2 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.1 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0 0.4 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.5 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.1 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.0 0.5 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.2 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.8 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.3 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.7 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.1 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.1 GO:0006113 fermentation(GO:0006113) regulation of fermentation(GO:0043465) positive regulation of skeletal muscle tissue growth(GO:0048633) regulation of NAD metabolic process(GO:1902688)
0.0 0.2 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242)
0.0 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.3 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.4 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.1 GO:0035048 splicing factor protein import into nucleus(GO:0035048)
0.0 0.4 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.2 GO:0007549 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.4 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.4 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.5 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.1 GO:0019605 butyrate metabolic process(GO:0019605)
0.0 0.2 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.0 0.1 GO:0036116 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.1 GO:0003420 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) histone H3-R2 methylation(GO:0034970)
0.0 0.0 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.1 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.0 0.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.0 0.1 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.4 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.4 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.4 GO:0030157 pancreatic juice secretion(GO:0030157)
0.0 0.4 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0021764 amygdala development(GO:0021764)
0.0 0.1 GO:1900228 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229) positive regulation of chondrocyte proliferation(GO:1902732)
0.0 0.0 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.1 GO:0021893 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.1 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.3 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.3 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.2 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.0 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.0 0.0 GO:1901874 negative regulation of post-translational protein modification(GO:1901874)
0.0 0.1 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.4 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.0 0.4 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.3 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.0 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.4 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.4 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.3 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.1 0.2 GO:0005760 gamma DNA polymerase complex(GO:0005760)
0.1 0.3 GO:0042643 actomyosin, actin portion(GO:0042643)
0.1 0.5 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.1 0.7 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.3 GO:0045160 myosin I complex(GO:0045160)
0.0 0.7 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.7 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.0 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.3 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.8 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.6 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.0 0.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.3 GO:0016600 flotillin complex(GO:0016600)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 1.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0035363 histone locus body(GO:0035363)
0.0 0.4 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.3 GO:0071439 clathrin complex(GO:0071439)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.6 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0097013 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279) phagocytic vesicle lumen(GO:0097013)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.6 GO:0031941 filamentous actin(GO:0031941)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.2 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.2 0.7 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 1.3 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.1 1.7 GO:0050693 LBD domain binding(GO:0050693)
0.1 2.0 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 1.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.3 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 0.4 GO:0030395 lactose binding(GO:0030395)
0.1 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.5 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.2 GO:0008892 guanine deaminase activity(GO:0008892)
0.1 0.3 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 0.8 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.2 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 0.4 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 0.3 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.5 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.3 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.4 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.7 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.9 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.6 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.3 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.3 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.4 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.1 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.5 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.5 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.3 GO:0019534 toxin transporter activity(GO:0019534)
0.0 1.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) primary miRNA binding(GO:0070878)
0.0 0.1 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.4 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.0 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.1 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.0 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0 0.1 GO:0017018 myosin phosphatase activity(GO:0017018)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 2.2 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.0 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 2.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.6 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.9 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.2 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.3 PID MYC PATHWAY C-MYC pathway
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 3.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.6 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.9 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.7 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 1.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 1.5 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.6 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.3 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.0 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.9 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.7 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.6 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism