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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for KLF12

Z-value: 0.87

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Transcription factors associated with KLF12

Gene Symbol Gene ID Gene Info
KLF12
ENSG00000118922.18 KLF12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF12hg38_v1_chr13_-_74133892_741339410.367.8e-02Click!

Activity profile of KLF12 motif

Sorted Z-values of KLF12 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF12

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr5_+_138465472 3.87 ENST00000239938.5
EGR1
early growth response 1
chr3_+_194136138 2.04 ENST00000232424.4
HES1
hes family bHLH transcription factor 1
chr4_-_74099187 1.96 ENST00000508487.3
CXCL2
C-X-C motif chemokine ligand 2
chr2_-_224402097 1.74 ENST00000409685.4
FAM124B
family with sequence similarity 124 member B
chr2_-_224401994 1.73 ENST00000389874.3
FAM124B
family with sequence similarity 124 member B
chr1_+_153778178 1.58 ENST00000532853.5
SLC27A3
solute carrier family 27 member 3
chr15_-_52652031 1.57 ENST00000546305.6
FAM214A
family with sequence similarity 214 member A
chr4_-_74038681 1.41 ENST00000296026.4
CXCL3
C-X-C motif chemokine ligand 3
chr4_+_73869385 1.33 ENST00000395761.4
CXCL1
C-X-C motif chemokine ligand 1
chr2_-_219571241 1.33 ENST00000373876.5
ENST00000603926.5
ENST00000373873.8
ENST00000289656.3
OBSL1
obscurin like cytoskeletal adaptor 1
chr6_+_116511626 1.31 ENST00000368599.4
CALHM5
calcium homeostasis modulator family member 5
chr17_+_28744034 1.27 ENST00000444415.7
ENST00000262396.10
TRAF4
TNF receptor associated factor 4
chr9_-_131276499 1.25 ENST00000372271.4
FAM78A
family with sequence similarity 78 member A
chr20_-_40689228 1.23 ENST00000373313.3
MAFB
MAF bZIP transcription factor B
chr1_+_203305510 1.21 ENST00000290551.5
BTG2
BTG anti-proliferation factor 2
chr19_+_45469841 1.20 ENST00000592811.5
ENST00000586615.5
FOSB
FosB proto-oncogene, AP-1 transcription factor subunit
chr12_-_95790755 1.19 ENST00000343702.9
ENST00000344911.8
NTN4
netrin 4
chr10_-_79445617 1.18 ENST00000372336.4
ZCCHC24
zinc finger CCHC-type containing 24
chr1_+_60865259 1.08 ENST00000371191.5
NFIA
nuclear factor I A
chr17_-_49764123 1.06 ENST00000240364.7
ENST00000506156.1
FAM117A
family with sequence similarity 117 member A
chr14_-_91946989 1.05 ENST00000556154.5
FBLN5
fibulin 5
chr2_+_233195433 1.01 ENST00000417661.1
INPP5D
inositol polyphosphate-5-phosphatase D
chr14_+_58298497 0.96 ENST00000348476.7
ENST00000355431.8
ENST00000395168.7
ARID4A
AT-rich interaction domain 4A
chr1_-_46132650 0.94 ENST00000372006.5
ENST00000425892.2
ENST00000420542.5
PIK3R3
phosphoinositide-3-kinase regulatory subunit 3
chr3_-_149086488 0.92 ENST00000392912.6
ENST00000465259.5
ENST00000310053.10
ENST00000494055.5
HLTF
helicase like transcription factor
chr11_-_61361834 0.87 ENST00000544118.5
ENST00000294072.9
ENST00000545361.5
ENST00000539128.5
ENST00000546151.5
ENST00000447532.6
CYB561A3
cytochrome b561 family member A3
chr11_+_7513966 0.86 ENST00000299492.9
PPFIBP2
PPFIA binding protein 2
chr12_+_93572664 0.85 ENST00000551556.2
SOCS2
suppressor of cytokine signaling 2
chr17_+_1762052 0.85 ENST00000254722.9
ENST00000576406.5
ENST00000571149.5
SERPINF1
serpin family F member 1
chr20_+_36154630 0.84 ENST00000338074.7
ENST00000636016.2
ENST00000373945.5
EPB41L1
erythrocyte membrane protein band 4.1 like 1
chr2_+_24049673 0.83 ENST00000380991.8
FKBP1B
FKBP prolyl isomerase 1B
chr17_-_5500997 0.81 ENST00000568641.2
ENSG00000286190.2
novel protein
chr14_+_63204436 0.80 ENST00000316754.8
RHOJ
ras homolog family member J
chr2_+_24049705 0.80 ENST00000380986.9
ENST00000452109.1
FKBP1B
FKBP prolyl isomerase 1B
chr16_+_29807775 0.78 ENST00000568411.5
ENST00000563012.1
ENST00000562557.5
MAZ
MYC associated zinc finger protein
chr19_-_4558417 0.75 ENST00000586965.1
SEMA6B
semaphorin 6B
chr11_-_62707581 0.72 ENST00000684475.1
ENST00000683296.1
ENST00000684067.1
ENST00000682223.1
BSCL2
BSCL2 lipid droplet biogenesis associated, seipin
chr8_-_6563409 0.71 ENST00000325203.9
ANGPT2
angiopoietin 2
chr8_-_6563238 0.70 ENST00000629816.3
ENST00000523120.2
ANGPT2
angiopoietin 2
chr16_+_29807536 0.70 ENST00000567444.5
MAZ
MYC associated zinc finger protein
chr8_-_6563044 0.69 ENST00000338312.10
ANGPT2
angiopoietin 2
chr17_-_8630749 0.69 ENST00000379980.8
ENST00000269243.8
MYH10
myosin heavy chain 10
chr16_+_29808051 0.69 ENST00000568544.5
ENST00000569978.1
MAZ
MYC associated zinc finger protein
chr17_-_8630713 0.68 ENST00000411957.1
ENST00000360416.8
MYH10
myosin heavy chain 10
chr16_+_69105636 0.67 ENST00000569188.6
HAS3
hyaluronan synthase 3
chr16_+_29808125 0.67 ENST00000568282.1
MAZ
MYC associated zinc finger protein
chr22_+_25111810 0.67 ENST00000637069.1
KIAA1671
KIAA1671
chr14_+_73950489 0.66 ENST00000554320.1
COQ6
coenzyme Q6, monooxygenase
chr11_+_104036624 0.65 ENST00000302259.5
DDI1
DNA damage inducible 1 homolog 1
chr17_-_78903193 0.65 ENST00000322630.3
ENST00000586713.5
CEP295NL
CEP295 N-terminal like
chr2_+_172860038 0.64 ENST00000538974.5
ENST00000540783.5
RAPGEF4
Rap guanine nucleotide exchange factor 4
chr11_-_102530738 0.62 ENST00000260227.5
MMP7
matrix metallopeptidase 7
chr17_-_40994159 0.62 ENST00000391586.3
KRTAP3-3
keratin associated protein 3-3
chr6_+_11537738 0.61 ENST00000379426.2
TMEM170B
transmembrane protein 170B
chr11_-_65606959 0.60 ENST00000532507.5
MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr1_-_46132616 0.60 ENST00000423209.5
ENST00000262741.10
PIK3R3
phosphoinositide-3-kinase regulatory subunit 3
chr11_-_62707413 0.60 ENST00000360796.10
ENST00000449636.6
BSCL2
BSCL2 lipid droplet biogenesis associated, seipin
chr2_+_148021404 0.59 ENST00000638043.2
MBD5
methyl-CpG binding domain protein 5
chr1_+_92029971 0.59 ENST00000370383.5
EPHX4
epoxide hydrolase 4
chr5_-_81751022 0.58 ENST00000509013.2
ENST00000505980.5
ENST00000509053.5
SSBP2
single stranded DNA binding protein 2
chr16_+_2969270 0.57 ENST00000293978.12
PAQR4
progestin and adipoQ receptor family member 4
chr2_+_202634960 0.57 ENST00000392238.3
FAM117B
family with sequence similarity 117 member B
chr16_+_2969307 0.57 ENST00000576565.1
ENST00000318782.9
PAQR4
progestin and adipoQ receptor family member 4
chr2_+_188291661 0.56 ENST00000409843.5
GULP1
GULP PTB domain containing engulfment adaptor 1
chr11_+_121590388 0.56 ENST00000527934.1
SORL1
sortilin related receptor 1
chrX_-_45200895 0.55 ENST00000377934.4
DIPK2B
divergent protein kinase domain 2B
chr14_-_22819721 0.53 ENST00000554517.5
ENST00000285850.11
ENST00000397529.6
ENST00000555702.5
SLC7A7
solute carrier family 7 member 7
chr5_-_81751085 0.53 ENST00000515395.5
SSBP2
single stranded DNA binding protein 2
chr16_-_31508370 0.52 ENST00000430477.6
ENST00000567994.5
ENST00000570164.5
ENST00000327237.7
RUSF1
RUS family member 1
chr10_+_61901678 0.52 ENST00000644638.1
ENST00000681100.1
ENST00000279873.12
ARID5B
AT-rich interaction domain 5B
chr12_+_12725897 0.50 ENST00000326765.10
APOLD1
apolipoprotein L domain containing 1
chr8_+_96493803 0.50 ENST00000518385.5
ENST00000302190.9
SDC2
syndecan 2
chr2_+_36696686 0.50 ENST00000379242.7
ENST00000389975.7
VIT
vitrin
chr19_+_43612083 0.49 ENST00000417606.3
SRRM5
serine/arginine repetitive matrix 5
chr7_-_27185223 0.48 ENST00000517402.1
ENST00000006015.4
HOXA11
homeobox A11
chr6_-_31897200 0.48 ENST00000395728.7
ENST00000375528.8
EHMT2
euchromatic histone lysine methyltransferase 2
chr22_+_46620380 0.48 ENST00000406902.6
GRAMD4
GRAM domain containing 4
chr11_-_119340816 0.47 ENST00000528368.3
C1QTNF5
C1q and TNF related 5
chr14_+_63204859 0.46 ENST00000555125.1
RHOJ
ras homolog family member J
chr12_+_7061206 0.46 ENST00000423384.5
ENST00000413211.5
C1S
complement C1s
chrX_-_71254106 0.46 ENST00000373984.7
ENST00000314425.9
ENST00000373982.5
ZMYM3
zinc finger MYM-type containing 3
chr14_+_75002903 0.46 ENST00000266126.10
EIF2B2
eukaryotic translation initiation factor 2B subunit beta
chr2_+_178194460 0.45 ENST00000392505.6
ENST00000359685.7
ENST00000357080.8
ENST00000190611.9
ENST00000409045.7
OSBPL6
oxysterol binding protein like 6
chrX_+_54809060 0.45 ENST00000396224.1
MAGED2
MAGE family member D2
chr17_+_2337480 0.44 ENST00000268989.8
ENST00000426855.6
SGSM2
small G protein signaling modulator 2
chr7_-_122995700 0.44 ENST00000249284.3
TAS2R16
taste 2 receptor member 16
chr5_+_75337192 0.43 ENST00000680160.1
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
chr5_+_75337261 0.43 ENST00000680940.1
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
chr5_+_75337211 0.43 ENST00000287936.9
ENST00000343975.9
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
chr7_-_27662836 0.42 ENST00000265395.7
HIBADH
3-hydroxyisobutyrate dehydrogenase
chr11_-_119340544 0.42 ENST00000530681.2
C1QTNF5
C1q and TNF related 5
chr5_+_75337348 0.42 ENST00000681271.1
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
chr16_+_31459950 0.42 ENST00000564900.1
ARMC5
armadillo repeat containing 5
chr18_-_55585773 0.41 ENST00000563824.5
ENST00000626425.2
ENST00000566514.5
ENST00000568673.5
ENST00000562847.5
ENST00000568147.5
TCF4
transcription factor 4
chr2_+_218880844 0.41 ENST00000258411.8
WNT10A
Wnt family member 10A
chr9_+_34652167 0.41 ENST00000441545.7
ENST00000553620.5
IL11RA
interleukin 11 receptor subunit alpha
chr2_-_55296361 0.40 ENST00000647547.1
CCDC88A
coiled-coil domain containing 88A
chr2_-_127643212 0.40 ENST00000409286.5
LIMS2
LIM zinc finger domain containing 2
chr21_-_43060546 0.40 ENST00000430013.1
CBS
cystathionine beta-synthase
chr19_+_36111151 0.40 ENST00000633214.1
ENST00000585332.3
OVOL3
ovo like zinc finger 3
chr16_+_28863812 0.39 ENST00000684370.1
SH2B1
SH2B adaptor protein 1
chr10_-_102120246 0.39 ENST00000425280.2
LDB1
LIM domain binding 1
chr3_-_49685090 0.39 ENST00000448220.5
MST1
macrophage stimulating 1
chr1_-_203175783 0.39 ENST00000621380.1
ENST00000255416.9
MYBPH
myosin binding protein H
chr10_-_89643870 0.38 ENST00000322191.10
ENST00000342512.3
PANK1
pantothenate kinase 1
chr12_+_57089094 0.38 ENST00000342556.6
ENST00000300131.8
NAB2
NGFI-A binding protein 2
chr17_+_997101 0.38 ENST00000327158.5
TIMM22
translocase of inner mitochondrial membrane 22
chr20_+_35699442 0.38 ENST00000374072.5
ENST00000397416.1
ENST00000336695.4
ROMO1
reactive oxygen species modulator 1
chr16_+_75222609 0.38 ENST00000495583.1
CTRB1
chymotrypsinogen B1
chr11_-_1757452 0.37 ENST00000427721.3
ENSG00000250644.3
novel protein
chrX_-_10576901 0.37 ENST00000380779.5
MID1
midline 1
chr1_+_150067668 0.36 ENST00000611412.4
ENST00000644510.2
ENST00000643611.1
VPS45
vacuolar protein sorting 45 homolog
chr19_+_40627033 0.36 ENST00000599225.1
ENST00000598166.2
LTBP4
latent transforming growth factor beta binding protein 4
chr12_-_6663083 0.36 ENST00000467678.5
ENST00000493873.1
ENST00000412586.6
ENST00000423703.6
ENST00000444704.5
ENST00000341550.9
ING4
inhibitor of growth family member 4
chr9_-_96302142 0.35 ENST00000648799.1
HSD17B3
hydroxysteroid 17-beta dehydrogenase 3
chr1_-_202808406 0.35 ENST00000650569.1
ENST00000367265.9
ENST00000649770.1
KDM5B
lysine demethylase 5B
chr5_-_108381109 0.35 ENST00000619412.4
FBXL17
F-box and leucine rich repeat protein 17
chr3_-_128493173 0.35 ENST00000498200.1
ENST00000341105.7
GATA2
GATA binding protein 2
chr19_+_49877660 0.35 ENST00000535102.6
TBC1D17
TBC1 domain family member 17
chr11_+_62707668 0.35 ENST00000294117.6
GNG3
G protein subunit gamma 3
chr1_-_45206594 0.35 ENST00000359600.6
ZSWIM5
zinc finger SWIM-type containing 5
chr15_+_40239420 0.35 ENST00000560346.5
PAK6
p21 (RAC1) activated kinase 6
chr12_+_6951271 0.35 ENST00000456013.5
PTPN6
protein tyrosine phosphatase non-receptor type 6
chr18_+_58864866 0.34 ENST00000588456.5
ENST00000591808.6
ENST00000589481.1
ENST00000591049.1
ZNF532
zinc finger protein 532
chr1_-_153628180 0.34 ENST00000339556.8
ENST00000440685.7
S100A13
S100 calcium binding protein A13
chr2_+_36696790 0.34 ENST00000497382.5
ENST00000404084.5
ENST00000379241.7
ENST00000401530.5
VIT
vitrin
chr16_-_740980 0.34 ENST00000251588.7
CIAO3
cytosolic iron-sulfur assembly component 3
chr16_-_740934 0.34 ENST00000540986.5
CIAO3
cytosolic iron-sulfur assembly component 3
chr17_-_81869934 0.33 ENST00000580685.5
ARHGDIA
Rho GDP dissociation inhibitor alpha
chr11_-_44950151 0.33 ENST00000533940.5
ENST00000533937.1
TP53I11
tumor protein p53 inducible protein 11
chr12_+_6946468 0.33 ENST00000543115.5
ENST00000399448.5
PTPN6
protein tyrosine phosphatase non-receptor type 6
chrX_+_154429092 0.33 ENST00000619046.5
ATP6AP1
ATPase H+ transporting accessory protein 1
chr13_-_67230313 0.33 ENST00000377865.7
PCDH9
protocadherin 9
chr19_+_49877694 0.33 ENST00000221543.10
TBC1D17
TBC1 domain family member 17
chr1_+_15756659 0.33 ENST00000375771.5
FBLIM1
filamin binding LIM protein 1
chr6_-_43053832 0.33 ENST00000265348.9
ENST00000674134.1
ENST00000674100.1
CUL7
cullin 7
chr16_+_31459479 0.33 ENST00000268314.9
ARMC5
armadillo repeat containing 5
chrX_-_130165825 0.33 ENST00000675240.1
ENST00000319908.8
ENST00000674546.1
ENST00000287295.8
AIFM1
apoptosis inducing factor mitochondria associated 1
chr1_+_150067820 0.33 ENST00000419023.3
ENST00000644526.1
VPS45
vacuolar protein sorting 45 homolog
chr15_+_40239042 0.32 ENST00000558055.5
ENST00000455577.6
PAK6
p21 (RAC1) activated kinase 6
chr15_-_72783611 0.32 ENST00000563907.5
ADPGK
ADP dependent glucokinase
chr1_-_202808464 0.32 ENST00000648469.1
ENST00000648338.1
ENST00000367264.7
ENST00000648473.1
ENST00000648056.1
ENST00000650368.1
KDM5B
lysine demethylase 5B
chr12_+_6951345 0.32 ENST00000318974.14
ENST00000541698.5
ENST00000542462.1
PTPN6
protein tyrosine phosphatase non-receptor type 6
chr22_-_31346317 0.32 ENST00000266269.10
PATZ1
POZ/BTB and AT hook containing zinc finger 1
chrX_-_130165873 0.32 ENST00000676229.1
AIFM1
apoptosis inducing factor mitochondria associated 1
chrX_+_152831054 0.32 ENST00000370274.8
NSDHL
NAD(P) dependent steroid dehydrogenase-like
chr12_-_108731505 0.31 ENST00000261401.8
ENST00000552871.5
CORO1C
coronin 1C
chr14_+_57390544 0.31 ENST00000555166.5
ENST00000556492.6
ENST00000554703.1
NAA30
N-alpha-acetyltransferase 30, NatC catalytic subunit
chr15_-_72783685 0.31 ENST00000456471.3
ENST00000311669.12
ADPGK
ADP dependent glucokinase
chr16_+_2969548 0.31 ENST00000572687.1
PAQR4
progestin and adipoQ receptor family member 4
chr9_+_113444725 0.31 ENST00000374140.6
RGS3
regulator of G protein signaling 3
chr17_-_39401593 0.31 ENST00000394294.7
ENST00000264658.11
ENST00000583610.5
ENST00000647139.1
FBXL20
F-box and leucine rich repeat protein 20
chr15_+_41493860 0.30 ENST00000260386.7
ITPKA
inositol-trisphosphate 3-kinase A
chrX_-_112840815 0.30 ENST00000304758.5
ENST00000371959.9
AMOT
angiomotin
chr16_-_27549887 0.30 ENST00000561623.5
ENST00000356183.9
GTF3C1
general transcription factor IIIC subunit 1
chr13_-_67230377 0.30 ENST00000544246.5
ENST00000377861.4
PCDH9
protocadherin 9
chr11_+_66593194 0.30 ENST00000310190.8
CCS
copper chaperone for superoxide dismutase
chr10_-_102120318 0.30 ENST00000673968.1
LDB1
LIM domain binding 1
chr7_+_37920602 0.30 ENST00000199448.9
ENST00000423717.1
EPDR1
ependymin related 1
chr14_+_104724221 0.30 ENST00000330877.7
ADSS1
adenylosuccinate synthase 1
chr2_+_233636502 0.30 ENST00000373445.1
UGT1A10
UDP glucuronosyltransferase family 1 member A10
chr16_-_19886133 0.30 ENST00000568214.1
ENST00000569479.5
GPRC5B
G protein-coupled receptor class C group 5 member B
chrX_-_130165664 0.30 ENST00000535724.6
ENST00000346424.6
ENST00000676436.1
AIFM1
apoptosis inducing factor mitochondria associated 1
chr6_+_20401864 0.29 ENST00000346618.8
ENST00000613242.4
E2F3
E2F transcription factor 3
chr17_+_28662183 0.29 ENST00000347486.8
ENST00000314616.11
SUPT6H
SPT6 homolog, histone chaperone and transcription elongation factor
chr16_+_57976435 0.29 ENST00000290871.10
ENST00000441824.4
TEPP
testis, prostate and placenta expressed
chr17_+_2337622 0.29 ENST00000574563.5
SGSM2
small G protein signaling modulator 2
chr20_+_63235883 0.29 ENST00000342412.10
BIRC7
baculoviral IAP repeat containing 7
chr14_+_51847145 0.29 ENST00000615906.4
GNG2
G protein subunit gamma 2
chr9_-_125189721 0.28 ENST00000456642.1
ENST00000373547.9
ENST00000415905.5
ENST00000451402.5
PPP6C
protein phosphatase 6 catalytic subunit
chr2_-_113241779 0.28 ENST00000497038.6
PAX8
paired box 8
chr1_+_155127866 0.28 ENST00000368406.2
ENST00000368407.8
EFNA1
ephrin A1
chr9_-_96302170 0.28 ENST00000375263.8
HSD17B3
hydroxysteroid 17-beta dehydrogenase 3
chr14_+_103715724 0.28 ENST00000216602.10
ZFYVE21
zinc finger FYVE-type containing 21
chr14_+_103715767 0.27 ENST00000311141.7
ZFYVE21
zinc finger FYVE-type containing 21
chr16_+_6483379 0.27 ENST00000552089.5
RBFOX1
RNA binding fox-1 homolog 1
chr10_+_97713694 0.27 ENST00000285605.8
MARVELD1
MARVEL domain containing 1
chrX_-_84188148 0.27 ENST00000262752.5
RPS6KA6
ribosomal protein S6 kinase A6
chr17_+_82519694 0.27 ENST00000335255.10
FOXK2
forkhead box K2
chr12_-_70754631 0.26 ENST00000440835.6
ENST00000549308.5
ENST00000550661.1
ENST00000378778.5
PTPRR
protein tyrosine phosphatase receptor type R
chr1_+_109249530 0.26 ENST00000271332.4
CELSR2
cadherin EGF LAG seven-pass G-type receptor 2
chr19_-_55175031 0.26 ENST00000587067.1
SYT5
synaptotagmin 5
chr20_-_54070520 0.26 ENST00000371435.6
ENST00000395961.7
BCAS1
brain enriched myelin associated protein 1
chr17_+_44557476 0.26 ENST00000315323.5
FZD2
frizzled class receptor 2
chr17_+_4715438 0.26 ENST00000571206.1
ARRB2
arrestin beta 2
chr19_-_45768627 0.26 ENST00000560160.1
SIX5
SIX homeobox 5
chr20_+_35699368 0.26 ENST00000374077.8
ROMO1
reactive oxygen species modulator 1
chr16_-_30787169 0.26 ENST00000262525.6
ZNF629
zinc finger protein 629
chr16_-_67944113 0.25 ENST00000264005.10
LCAT
lecithin-cholesterol acyltransferase
chr6_-_166167832 0.25 ENST00000366876.7
TBXT
T-box transcription factor T
chrX_-_130165699 0.25 ENST00000676328.1
ENST00000675857.1
ENST00000675427.1
ENST00000675092.1
AIFM1
apoptosis inducing factor mitochondria associated 1
chr11_+_66593171 0.25 ENST00000533244.6
CCS
copper chaperone for superoxide dismutase
chr17_+_28744002 0.25 ENST00000618771.1
ENST00000262395.10
ENST00000422344.5
TRAF4
TNF receptor associated factor 4
chr19_+_49877425 0.25 ENST00000622860.4
TBC1D17
TBC1 domain family member 17
chrX_-_135052114 0.24 ENST00000370775.3
RTL8A
retrotransposon Gag like 8A
chr6_-_107115493 0.24 ENST00000369042.6
BEND3
BEN domain containing 3
chr20_+_35699227 0.23 ENST00000374078.5
ROMO1
reactive oxygen species modulator 1
chr16_-_9943182 0.23 ENST00000535259.6
GRIN2A
glutamate ionotropic receptor NMDA type subunit 2A
chr9_-_136050502 0.23 ENST00000371753.5
NACC2
NACC family member 2
chr10_+_102644462 0.23 ENST00000643721.2
ENST00000302424.12
TRIM8
tripartite motif containing 8

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0050720 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720) response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759) regulation of progesterone biosynthetic process(GO:2000182)
0.7 2.1 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.7 2.0 GO:0042668 trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164) negative regulation of pro-B cell differentiation(GO:2000974)
0.3 1.4 GO:0021592 fourth ventricle development(GO:0021592)
0.3 1.2 GO:0035284 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.3 1.2 GO:1904045 cellular response to aldosterone(GO:1904045)
0.3 1.0 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2 3.4 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.2 0.7 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.2 1.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.2 1.0 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.2 0.6 GO:1902948 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.2 1.0 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 0.7 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.1 0.9 GO:0071279 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) cellular response to cobalt ion(GO:0071279)
0.1 0.5 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 4.0 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 1.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.6 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 1.7 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.3 GO:0014028 notochord formation(GO:0014028)
0.1 0.6 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 0.4 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.1 0.5 GO:0008218 bioluminescence(GO:0008218)
0.1 1.5 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.5 GO:0051552 flavone metabolic process(GO:0051552)
0.1 0.4 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 0.5 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 0.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 0.3 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.4 GO:0006574 valine catabolic process(GO:0006574)
0.1 0.4 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.5 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 0.4 GO:0006535 cysteine biosynthetic process from serine(GO:0006535) cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) homocysteine catabolic process(GO:0043418) L-cysteine metabolic process(GO:0046439)
0.1 0.3 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1 0.2 GO:2000591 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) metanephric mesangial cell differentiation(GO:0072209) metanephric glomerular mesangial cell differentiation(GO:0072254) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.1 0.3 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.1 1.6 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.1 0.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.2 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.1 0.9 GO:0051715 cytolysis in other organism(GO:0051715)
0.1 0.6 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.6 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.1 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.3 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 1.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.3 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 1.0 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:1990927 short-term synaptic potentiation(GO:1990926) calcium ion regulated lysosome exocytosis(GO:1990927)
0.0 1.5 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.3 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.4 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.0 0.2 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 0.2 GO:0033058 directional locomotion(GO:0033058)
0.0 0.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.1 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) maintenance of mitochondrion location(GO:0051659)
0.0 1.2 GO:0051412 response to corticosterone(GO:0051412)
0.0 0.3 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.6 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 1.0 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.0 0.3 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.3 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 1.1 GO:0072189 ureter development(GO:0072189)
0.0 0.2 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.3 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.2 GO:0051697 protein delipidation(GO:0051697)
0.0 0.4 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.3 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.5 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.5 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.6 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.3 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 2.9 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.4 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.3 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.1 GO:0071931 positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931)
0.0 0.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.3 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.1 GO:1904640 response to methionine(GO:1904640)
0.0 0.6 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.6 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.5 GO:0044849 estrous cycle(GO:0044849)
0.0 0.2 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.3 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 0.3 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.2 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.3 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.4 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.2 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.1 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.5 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.0 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
0.0 0.2 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.2 GO:0034036 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.0 0.2 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.0 0.8 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.2 GO:0060346 bone trabecula formation(GO:0060346)
0.0 0.3 GO:0060022 hard palate development(GO:0060022)
0.0 0.3 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.4 GO:0034033 coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0 0.1 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.5 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.3 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.4 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.0 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.2 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.7 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.1 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.7 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.9 GO:0070206 protein trimerization(GO:0070206)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.7 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.2 GO:0010225 response to UV-C(GO:0010225)
0.0 0.1 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:1990393 3M complex(GO:1990393)
0.3 1.4 GO:0097513 myosin II filament(GO:0097513)
0.2 0.5 GO:0036117 hyaluranon cable(GO:0036117)
0.2 0.6 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 1.0 GO:0071953 elastic fiber(GO:0071953)
0.1 1.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.9 GO:0043203 axon hillock(GO:0043203)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.4 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.3 GO:0031417 NatC complex(GO:0031417)
0.1 0.3 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.4 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.9 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 1.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.6 GO:0010369 chromocenter(GO:0010369)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0016600 flotillin complex(GO:0016600)
0.0 1.8 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.4 GO:0032982 myosin filament(GO:0032982)
0.0 0.0 GO:0031251 PAN complex(GO:0031251)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 1.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.7 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.4 1.7 GO:0042282 hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282)
0.3 1.6 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.3 4.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 1.0 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.2 1.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 1.4 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.6 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.6 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.1 0.9 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.3 GO:0000252 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity(GO:0047012)
0.1 0.4 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 0.7 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.1 0.3 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.1 0.4 GO:0070025 oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.1 1.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 1.5 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.6 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.1 1.8 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 0.3 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.6 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.1 0.6 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 1.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.4 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.7 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.2 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 0.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.3 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 1.1 GO:0071949 FAD binding(GO:0071949)
0.0 1.3 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.3 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.6 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.5 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.3 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.7 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.4 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0000182 rDNA binding(GO:0000182)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 2.2 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.4 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.6 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.5 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.3 GO:0031005 filamin binding(GO:0031005)
0.0 1.1 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 1.0 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.5 GO:0032452 histone demethylase activity(GO:0032452)
0.0 4.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.6 GO:0030552 cAMP binding(GO:0030552)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 2.1 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.8 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.8 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.3 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.0 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.8 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.7 PID SHP2 PATHWAY SHP2 signaling
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.9 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.9 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.0 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.4 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 1.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 4.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.0 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 2.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 3.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.2 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.5 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.0 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 1.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.2 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.2 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.9 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions