Project

Inflammatory response time course, HUVEC (Wada, 2009)

Navigation
Downloads

Results for KLF7

Z-value: 0.51

Motif logo

logo of

Transcription factors associated with KLF7

Gene Symbol Gene ID Gene Info
KLF7
ENSG00000118263.15 KLF7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF7hg38_v1_chr2_-_207167220_2071672670.442.8e-02Click!

Activity profile of KLF7 motif

Sorted Z-values of KLF7 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF7

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr8_+_89757789 1.64 ENST00000220751.5
RIPK2
receptor interacting serine/threonine kinase 2
chr1_-_161132577 1.62 ENST00000464113.1
DEDD
death effector domain containing
chr1_-_161132659 1.25 ENST00000368006.8
ENST00000490843.6
ENST00000545495.5
DEDD
death effector domain containing
chr4_+_155758990 1.12 ENST00000505154.5
ENST00000652626.1
ENST00000502959.5
ENST00000264424.13
ENST00000505764.5
ENST00000507146.5
ENST00000503520.5
GUCY1B1
guanylate cyclase 1 soluble subunit beta 1
chr4_+_155759365 1.01 ENST00000513437.1
GUCY1B1
guanylate cyclase 1 soluble subunit beta 1
chr8_+_17247030 0.84 ENST00000521829.5
ENST00000521005.1
VPS37A
VPS37A subunit of ESCRT-I
chr8_+_17246921 0.55 ENST00000518038.1
ENST00000324849.9
VPS37A
VPS37A subunit of ESCRT-I
chr8_+_11284789 0.54 ENST00000221086.8
MTMR9
myotubularin related protein 9
chr6_+_43635832 0.54 ENST00000372171.5
MAD2L1BP
MAD2L1 binding protein
chr14_-_100568070 0.53 ENST00000557378.6
ENST00000443071.6
ENST00000637646.1
BEGAIN
brain enriched guanylate kinase associated
chr17_+_19378476 0.52 ENST00000395604.8
ENST00000482850.1
MAPK7
mitogen-activated protein kinase 7
chr1_-_157138474 0.51 ENST00000326786.4
ETV3
ETS variant transcription factor 3
chr5_+_173888335 0.46 ENST00000265085.10
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr17_-_18314956 0.43 ENST00000321105.10
ENST00000542570.5
TOP3A
DNA topoisomerase III alpha
chr19_+_38899946 0.43 ENST00000572515.5
ENST00000313582.6
ENST00000575359.5
NFKBIB
NFKB inhibitor beta
chr19_+_38899680 0.42 ENST00000576510.5
ENST00000392079.7
NFKBIB
NFKB inhibitor beta
chr15_+_92393841 0.41 ENST00000268164.8
ENST00000539113.5
ENST00000555434.1
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr6_+_37257762 0.35 ENST00000373491.3
TBC1D22B
TBC1 domain family member 22B
chr2_+_97113600 0.33 ENST00000620383.1
ANKRD36
ankyrin repeat domain 36
chr6_-_109382397 0.29 ENST00000512821.5
CD164
CD164 molecule
chr17_+_18315273 0.28 ENST00000406438.5
SMCR8
SMCR8-C9orf72 complex subunit
chr1_+_26826682 0.26 ENST00000374142.9
ZDHHC18
zinc finger DHHC-type palmitoyltransferase 18
chr12_+_53380141 0.22 ENST00000551969.5
ENST00000327443.9
SP1
Sp1 transcription factor
chr6_-_109382460 0.22 ENST00000310786.10
CD164
CD164 molecule
chr17_-_82098187 0.21 ENST00000634990.1
FASN
fatty acid synthase
chr6_-_109382431 0.20 ENST00000324953.9
ENST00000275080.11
ENST00000413644.6
CD164
CD164 molecule
chr2_-_74482914 0.19 ENST00000290418.4
ENST00000393965.8
CCDC142
coiled-coil domain containing 142
chr1_-_157138388 0.18 ENST00000368192.9
ETV3
ETS variant transcription factor 3
chr9_+_127802858 0.18 ENST00000393706.6
ENST00000630236.2
ENST00000373247.7
ENST00000373228.5
FPGS
folylpolyglutamate synthase
chr2_+_97113496 0.18 ENST00000639293.1
ENST00000461153.7
ANKRD36
ankyrin repeat domain 36
chr17_-_4948519 0.17 ENST00000225655.6
PFN1
profilin 1
chr12_-_49188811 0.17 ENST00000295766.9
TUBA1A
tubulin alpha 1a
chr2_-_95991793 0.16 ENST00000456556.5
ENST00000619511.1
ANKRD36C
ankyrin repeat domain 36C
chr9_+_127803208 0.15 ENST00000373225.7
ENST00000431857.5
FPGS
folylpolyglutamate synthase
chr17_+_40219325 0.14 ENST00000585043.5
ENST00000394103.7
WIPF2
WAS/WASL interacting protein family member 2
chr12_-_49189053 0.14 ENST00000550767.6
ENST00000546918.1
ENST00000679733.1
ENST00000552924.2
ENST00000301071.12
TUBA1A
tubulin alpha 1a
chr3_+_179148341 0.13 ENST00000263967.4
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
chr9_-_125241327 0.12 ENST00000324460.7
ENST00000680272.1
ENST00000680032.1
HSPA5
heat shock protein family A (Hsp70) member 5
chr12_-_6753134 0.10 ENST00000203630.10
MLF2
myeloid leukemia factor 2
chr5_+_141968886 0.09 ENST00000347642.7
RNF14
ring finger protein 14
chr2_-_97589862 0.09 ENST00000258459.11
ENST00000438709.6
ANKRD36B
ankyrin repeat domain 36B
chr12_+_49961864 0.08 ENST00000293599.7
AQP5
aquaporin 5
chr19_-_45792755 0.08 ENST00000377735.7
ENST00000270223.7
DMWD
DM1 locus, WD repeat containing
chr17_-_82098223 0.07 ENST00000306749.4
ENST00000635197.1
FASN
fatty acid synthase
chr2_-_97589711 0.07 ENST00000359901.8
ANKRD36B
ankyrin repeat domain 36B
chr19_-_7629531 0.07 ENST00000358368.5
XAB2
XPA binding protein 2
chr8_-_17246846 0.07 ENST00000628418.1
ENST00000361272.9
ENST00000523917.5
CNOT7
CCR4-NOT transcription complex subunit 7
chr7_+_128791390 0.06 ENST00000459946.5
ENST00000378685.8
ENST00000464832.5
ENST00000472049.1
ENST00000488925.1
CCDC136
coiled-coil domain containing 136
chrX_-_25015924 0.06 ENST00000379044.5
ARX
aristaless related homeobox
chr21_+_31873010 0.06 ENST00000270112.7
HUNK
hormonally up-regulated Neu-associated kinase
chrX_-_93673558 0.06 ENST00000475430.2
ENST00000373079.4
NAP1L3
nucleosome assembly protein 1 like 3
chr17_+_40219276 0.04 ENST00000583268.1
ENST00000323571.9
WIPF2
WAS/WASL interacting protein family member 2
chr17_-_44385332 0.03 ENST00000648408.1
ITGA2B
integrin subunit alpha 2b
chr15_+_75282835 0.03 ENST00000434739.3
GOLGA6D
golgin A6 family member D
chr1_-_155273444 0.02 ENST00000355560.4
ENST00000368361.9
CLK2
CDC like kinase 2
chr2_+_74483067 0.02 ENST00000233623.11
ENST00000442235.6
ENST00000410003.5
TTC31
tetratricopeptide repeat domain 31
chr17_-_48817217 0.02 ENST00000393382.8
TTLL6
tubulin tyrosine ligase like 6
chr3_-_105869035 0.02 ENST00000447441.6
ENST00000403724.5
ENST00000405772.5
CBLB
Cbl proto-oncogene B
chr2_-_187565751 0.02 ENST00000421427.5
TFPI
tissue factor pathway inhibitor
chrX_+_93674194 0.02 ENST00000332647.5
ENST00000683942.1
FAM133A
family with sequence similarity 133 member A
chr6_-_33271835 0.00 ENST00000482399.5
ENST00000445902.3
VPS52
VPS52 subunit of GARP complex
chr15_+_57706725 0.00 ENST00000380557.4
ENST00000649091.1
POLR2M
RNA polymerase II subunit M

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
0.1 0.5 GO:0030806 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821)
0.1 0.3 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 0.7 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.1 0.2 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.0 1.4 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.3 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:1903891 regulation of ATF6-mediated unfolded protein response(GO:1903891)
0.0 0.4 GO:0006265 DNA topological change(GO:0006265)
0.0 0.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.0 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 2.6 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.1 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 1.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.3 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.1 GO:0042025 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 GO:0089720 caspase binding(GO:0089720)
0.1 0.3 GO:0004314 [acyl-carrier-protein] S-malonyltransferase activity(GO:0004314) 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420)
0.1 0.4 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.7 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 3.9 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.5 ST GA12 PATHWAY G alpha 12 Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 1.6 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.8 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.4 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway