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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for LMX1B_MNX1_RAX2

Z-value: 0.66

Motif logo

Transcription factors associated with LMX1B_MNX1_RAX2

Gene Symbol Gene ID Gene Info
ENSG00000136944.19 LMX1B
ENSG00000130675.15 MNX1
ENSG00000173976.16 RAX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LMX1Bhg38_v1_chr9_+_126613922_126613946-0.395.6e-02Click!
RAX2hg38_v1_chr19_-_3772211_37722380.067.6e-01Click!
MNX1hg38_v1_chr7_-_157010615_157010668-0.048.6e-01Click!

Activity profile of LMX1B_MNX1_RAX2 motif

Sorted Z-values of LMX1B_MNX1_RAX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of LMX1B_MNX1_RAX2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr4_-_76023489 2.68 ENST00000306602.3
C-X-C motif chemokine ligand 10
chr7_-_22194709 1.98 ENST00000458533.5
Rap guanine nucleotide exchange factor 5
chr1_-_150765735 1.64 ENST00000679898.1
ENST00000448301.7
ENST00000680664.1
ENST00000679512.1
ENST00000368985.8
ENST00000679582.1
cathepsin S
chr12_+_26195647 1.56 ENST00000535504.1
sarcospan
chr1_-_150765785 1.41 ENST00000680311.1
ENST00000681728.1
ENST00000680288.1
cathepsin S
chr2_+_151357583 1.41 ENST00000243347.5
TNF alpha induced protein 6
chr4_+_168497066 1.31 ENST00000261509.10
palladin, cytoskeletal associated protein
chr4_+_168497044 1.20 ENST00000505667.6
palladin, cytoskeletal associated protein
chr19_-_14979848 1.14 ENST00000594383.2
solute carrier family 1 member 6
chr3_+_173398438 1.11 ENST00000457714.5
neuroligin 1
chr10_-_73591330 0.96 ENST00000451492.5
ENST00000681793.1
ENST00000680396.1
ENST00000413442.5
ubiquitin specific peptidase 54
chr12_+_26195313 0.96 ENST00000422622.3
sarcospan
chr6_-_87095059 0.96 ENST00000369582.6
ENST00000610310.3
ENST00000630630.2
ENST00000627148.3
ENST00000625577.1
glycoprotein hormones, alpha polypeptide
chrX_+_30235894 0.93 ENST00000620842.1
MAGE family member B3
chr18_+_34593312 0.92 ENST00000591816.6
ENST00000588125.5
ENST00000684610.1
ENST00000683705.1
ENST00000598334.5
ENST00000588684.5
ENST00000554864.7
ENST00000399121.9
ENST00000595022.5
dystrobrevin alpha
chr5_-_24644968 0.90 ENST00000264463.8
cadherin 10
chr12_+_26195543 0.89 ENST00000242729.7
sarcospan
chr2_-_207167220 0.87 ENST00000421199.5
ENST00000457962.5
Kruppel like factor 7
chr1_-_100894775 0.86 ENST00000416479.1
ENST00000370113.7
exostosin like glycosyltransferase 2
chr1_-_100894818 0.85 ENST00000370114.8
exostosin like glycosyltransferase 2
chr3_-_79767987 0.85 ENST00000464233.6
roundabout guidance receptor 1
chr11_+_33039996 0.82 ENST00000432887.5
ENST00000528898.1
ENST00000531632.6
t-complex 11 like 1
chr4_+_168092530 0.81 ENST00000359299.8
annexin A10
chr5_+_67004618 0.81 ENST00000261569.11
ENST00000436277.5
microtubule associated serine/threonine kinase family member 4
chr3_-_157503574 0.79 ENST00000494677.5
ENST00000468233.5
ventricular zone expressed PH domain containing 1
chr18_-_36129305 0.78 ENST00000269187.10
ENST00000590986.5
ENST00000440549.6
solute carrier family 39 member 6
chr18_+_58341038 0.76 ENST00000679791.1
NEDD4 like E3 ubiquitin protein ligase
chr3_-_191282383 0.76 ENST00000427544.6
urotensin 2B
chr6_+_113857333 0.74 ENST00000612661.2
myristoylated alanine rich protein kinase C substrate
chr1_-_247458105 0.73 ENST00000641149.1
ENST00000641527.1
olfactory receptor family 2 subfamily B member 11
chr19_-_3557563 0.70 ENST00000389395.7
ENST00000355415.7
major facilitator superfamily domain containing 12
chr3_+_130850585 0.70 ENST00000505330.5
ENST00000504381.5
ENST00000507488.6
ATPase secretory pathway Ca2+ transporting 1
chr4_-_115113614 0.68 ENST00000264363.7
N-deacetylase and N-sulfotransferase 4
chr2_+_102418642 0.66 ENST00000264260.6
interleukin 18 receptor accessory protein
chr14_-_50561119 0.66 ENST00000555216.5
mitogen-activated protein kinase kinase kinase kinase 5
chr4_-_39977836 0.64 ENST00000303538.13
ENST00000503396.5
PDS5 cohesin associated factor A
chr11_-_124320197 0.64 ENST00000624618.2
olfactory receptor family 8 subfamily D member 2
chr4_-_115113822 0.63 ENST00000613194.4
N-deacetylase and N-sulfotransferase 4
chr7_-_22193824 0.62 ENST00000401957.6
Rap guanine nucleotide exchange factor 5
chr10_-_13707536 0.61 ENST00000632570.1
ENST00000477221.2
FERM domain containing 4A
chr1_-_158426237 0.59 ENST00000641042.1
olfactory receptor family 10 subfamily K member 2
chr18_-_74291924 0.59 ENST00000494131.6
ENST00000340533.9
ENST00000397914.4
cytochrome b5 type A
chr17_-_41467386 0.58 ENST00000225899.4
keratin 32
chr1_+_67685170 0.57 ENST00000370985.4
ENST00000370986.9
ENST00000650283.1
ENST00000648742.1
growth arrest and DNA damage inducible alpha
chr4_-_138242325 0.52 ENST00000280612.9
solute carrier family 7 member 11
chr2_+_186590022 0.51 ENST00000261023.8
ENST00000374907.7
integrin subunit alpha V
chr12_+_41437680 0.51 ENST00000649474.1
ENST00000539469.6
ENST00000298919.7
PDZ domain containing ring finger 4
chr10_+_24208774 0.50 ENST00000376456.8
ENST00000458595.5
ENST00000376452.7
ENST00000430453.6
KIAA1217
chr17_-_66229380 0.50 ENST00000205948.11
apolipoprotein H
chr12_+_53954870 0.49 ENST00000243103.4
homeobox C12
chr1_+_160400543 0.48 ENST00000368061.3
VANGL planar cell polarity protein 2
chr6_-_169250825 0.48 ENST00000676869.1
ENST00000676760.1
thrombospondin 2
chr12_-_27970047 0.47 ENST00000395868.7
parathyroid hormone like hormone
chr13_-_46142834 0.47 ENST00000674665.1
lymphocyte cytosolic protein 1
chr18_+_34593392 0.46 ENST00000684377.1
dystrobrevin alpha
chr15_-_55270383 0.46 ENST00000396307.6
RAB27A, member RAS oncogene family
chr15_-_55270280 0.46 ENST00000564609.5
RAB27A, member RAS oncogene family
chr1_-_152159227 0.45 ENST00000316073.3
repetin
chr15_-_55270874 0.44 ENST00000567380.5
ENST00000565972.5
ENST00000569493.5
RAB27A, member RAS oncogene family
chr5_+_126423122 0.44 ENST00000515200.5
GRAM domain containing 2B
chr5_+_126423176 0.43 ENST00000542322.5
ENST00000544396.5
GRAM domain containing 2B
chr5_+_126423363 0.43 ENST00000285689.8
GRAM domain containing 2B
chr6_-_36547400 0.43 ENST00000229812.8
serine/threonine kinase 38
chr15_+_92900189 0.42 ENST00000626874.2
ENST00000627622.1
ENST00000629346.2
ENST00000628375.2
ENST00000420239.7
ENST00000394196.9
chromodomain helicase DNA binding protein 2
chr1_+_100538131 0.42 ENST00000315033.5
G protein-coupled receptor 88
chr1_-_153967621 0.42 ENST00000413622.5
ENST00000310483.10
solute carrier family 39 member 1
chr4_+_70592295 0.40 ENST00000449493.2
ameloblastin
chr1_+_50103903 0.40 ENST00000371827.5
ELAV like RNA binding protein 4
chr8_-_108787563 0.39 ENST00000297459.4
transmembrane protein 74
chr3_+_111998739 0.38 ENST00000393917.6
ENST00000273368.8
transgelin 3
chr8_+_32647080 0.37 ENST00000520502.7
ENST00000523041.2
ENST00000650819.1
neuregulin 1
chr7_+_134779625 0.37 ENST00000454108.5
ENST00000361675.7
caldesmon 1
chr15_+_74788542 0.36 ENST00000567571.5
C-terminal Src kinase
chr15_+_92900338 0.35 ENST00000625990.3
chromodomain helicase DNA binding protein 2
chr3_+_111999189 0.35 ENST00000455401.6
transgelin 3
chr12_-_27970273 0.35 ENST00000542963.1
ENST00000535992.5
parathyroid hormone like hormone
chr3_+_133574434 0.35 ENST00000508481.5
ENST00000420115.6
ENST00000504867.5
ENST00000507408.5
ENST00000511392.5
ENST00000515421.1
CDV3 homolog
chr3_+_111998915 0.35 ENST00000478951.6
transgelin 3
chr1_-_152414256 0.34 ENST00000271835.3
cornulin
chr15_+_76336755 0.34 ENST00000290759.9
ISL LIM homeobox 2
chr17_-_79950828 0.34 ENST00000572862.5
ENST00000573782.5
ENST00000574427.1
ENST00000570373.5
ENST00000340848.11
ENST00000576768.5
TBC1 domain family member 16
chr10_-_29736956 0.33 ENST00000674475.1
supervillin
chr3_-_157499538 0.32 ENST00000392832.6
ventricular zone expressed PH domain containing 1
chr8_+_24440930 0.32 ENST00000441335.6
ENST00000175238.10
ENST00000380789.5
ADAM metallopeptidase domain 7
chr5_+_31193739 0.32 ENST00000514738.5
cadherin 6
chr7_+_134779663 0.32 ENST00000361901.6
caldesmon 1
chr12_+_92702843 0.31 ENST00000397833.3
pleckstrin homology and RhoGEF domain containing G7
chr4_+_70592253 0.31 ENST00000322937.10
ENST00000613447.4
ameloblastin
chr11_+_124183219 0.30 ENST00000641351.2
olfactory receptor family 10 subfamily D member 3
chr17_+_43211835 0.30 ENST00000588693.5
ENST00000588659.5
ENST00000541594.5
ENST00000536052.5
ENST00000612339.4
transmembrane protein 106A
chr3_-_33645433 0.29 ENST00000635664.1
ENST00000485378.6
ENST00000313350.10
ENST00000487200.5
cytoplasmic linker associated protein 2
chr2_+_158968608 0.29 ENST00000263635.8
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr1_+_206635521 0.28 ENST00000367109.8
dual specificity tyrosine phosphorylation regulated kinase 3
chr8_+_49911396 0.28 ENST00000642720.2
syntrophin gamma 1
chr18_+_58255433 0.28 ENST00000635997.1
NEDD4 like E3 ubiquitin protein ligase
chr1_+_183805105 0.28 ENST00000360851.4
ral guanine nucleotide dissociation stimulator like 1
chr12_+_80716906 0.27 ENST00000228644.4
myogenic factor 5
chr7_-_25228485 0.27 ENST00000222674.2
neuropeptide VF precursor
chr3_-_12545499 0.27 ENST00000564146.4
MKRN2 opposite strand
chr8_+_49911604 0.26 ENST00000642164.1
ENST00000644093.1
ENST00000643999.1
ENST00000647073.1
ENST00000646880.1
syntrophin gamma 1
chr1_-_113871665 0.26 ENST00000528414.5
ENST00000460620.5
ENST00000359785.10
ENST00000420377.6
ENST00000525799.1
ENST00000538253.5
protein tyrosine phosphatase non-receptor type 22
chr3_-_158106408 0.25 ENST00000483851.7
short stature homeobox 2
chr17_+_58755821 0.25 ENST00000308249.4
protein phosphatase, Mg2+/Mn2+ dependent 1E
chr9_-_21368962 0.25 ENST00000610660.1
interferon alpha 13
chr1_+_158461574 0.25 ENST00000641432.1
ENST00000641460.1
ENST00000641535.1
ENST00000641971.1
olfactory receptor family 10 subfamily K member 1
chr8_+_91249307 0.24 ENST00000309536.6
ENST00000276609.8
solute carrier family 26 member 7
chr6_+_26365176 0.24 ENST00000377708.7
butyrophilin subfamily 3 member A2
chr6_+_131250375 0.24 ENST00000474850.2
A-kinase anchoring protein 7
chr16_+_53099100 0.24 ENST00000565832.5
chromodomain helicase DNA binding protein 9
chr6_+_41053194 0.23 ENST00000244669.3
apolipoprotein B mRNA editing enzyme catalytic subunit 2
chr8_-_40897814 0.23 ENST00000297737.11
ENST00000315769.11
zinc finger matrin-type 4
chr5_-_36301883 0.23 ENST00000502994.5
ENST00000515759.5
ENST00000296604.8
RAN binding protein 3 like
chr21_+_34364003 0.23 ENST00000290310.4
potassium voltage-gated channel subfamily E regulatory subunit 2
chr11_-_102705737 0.22 ENST00000260229.5
matrix metallopeptidase 27
chr1_+_155051280 0.22 ENST00000449910.6
ENST00000359280.8
ENST00000360674.8
ENST00000368412.7
ENST00000355956.6
ENST00000271836.10
ENST00000368413.5
ENST00000356955.7
ENST00000531455.5
ENST00000447332.3
ADAM metallopeptidase domain 15
chr6_+_26365215 0.22 ENST00000527422.5
ENST00000356386.6
ENST00000396948.5
butyrophilin subfamily 3 member A2
chr2_+_157257687 0.22 ENST00000259056.5
polypeptide N-acetylgalactosaminyltransferase 5
chrX_-_13817027 0.22 ENST00000493677.5
ENST00000355135.6
ENST00000316715.9
glycoprotein M6B
chr2_+_68734861 0.22 ENST00000467265.5
Rho GTPase activating protein 25
chr2_-_189179754 0.21 ENST00000374866.9
ENST00000618828.1
collagen type V alpha 2 chain
chr6_+_159890964 0.21 ENST00000434562.2
ENST00000674077.2
novel transcript
MAS1 proto-oncogene, G protein-coupled receptor
chr6_+_29301701 0.21 ENST00000641895.1
olfactory receptor family 14 subfamily J member 1
chr7_-_78771108 0.20 ENST00000626691.2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr12_-_86256267 0.20 ENST00000620241.4
MGAT4 family member C
chr11_+_111245725 0.20 ENST00000280325.7
chromosome 11 open reading frame 53
chr6_+_106360668 0.20 ENST00000633556.3
crystallin beta-gamma domain containing 1
chr12_-_110499546 0.20 ENST00000552130.6
VPS29 retromer complex component
chr4_-_122621011 0.19 ENST00000611104.2
ENST00000648588.1
interleukin 21
chr5_+_31193678 0.19 ENST00000265071.3
cadherin 6
chrX_-_21658324 0.19 ENST00000379499.3
kelch like family member 34
chr6_+_150721073 0.19 ENST00000358517.6
pleckstrin homology and RhoGEF domain containing G1
chr11_-_120138104 0.19 ENST00000341846.10
tripartite motif containing 29
chr2_+_68734773 0.18 ENST00000409202.8
Rho GTPase activating protein 25
chr11_-_30586866 0.18 ENST00000528686.2
metallophosphoesterase domain containing 2
chr13_+_108629605 0.18 ENST00000457511.7
myosin XVI
chr18_-_3219849 0.18 ENST00000261606.11
myomesin 1
chr4_-_145180496 0.18 ENST00000447906.8
OTU deubiquitinase 4
chr12_+_92702983 0.17 ENST00000344636.6
ENST00000544406.2
pleckstrin homology and RhoGEF domain containing G7
chr8_-_12755457 0.17 ENST00000398246.8
LON peptidase N-terminal domain and ring finger 1
chr18_+_63907948 0.17 ENST00000238508.8
serpin family B member 10
chr6_-_100464912 0.17 ENST00000369208.8
SIM bHLH transcription factor 1
chr8_-_115492221 0.16 ENST00000518018.1
transcriptional repressor GATA binding 1
chr1_+_107139996 0.16 ENST00000370073.6
ENST00000370074.8
netrin G1
chr3_+_63443306 0.16 ENST00000472899.5
ENST00000479198.5
ENST00000460711.5
ENST00000465156.1
synaptoporin
chr12_-_21775581 0.16 ENST00000537950.1
ENST00000665145.1
potassium inwardly rectifying channel subfamily J member 8
chr1_+_160190567 0.16 ENST00000368078.8
calsequestrin 1
chr5_+_68290637 0.16 ENST00000336483.9
phosphoinositide-3-kinase regulatory subunit 1
chr13_+_76948500 0.16 ENST00000377462.6
aconitate decarboxylase 1
chr6_-_136526472 0.16 ENST00000454590.5
ENST00000432797.6
microtubule associated protein 7
chr2_-_213151590 0.16 ENST00000374319.8
ENST00000457361.5
ENST00000451136.6
ENST00000434687.6
IKAROS family zinc finger 2
chr8_+_104223344 0.16 ENST00000523362.5
regulating synaptic membrane exocytosis 2
chr4_-_99144238 0.16 ENST00000512499.5
ENST00000504125.1
ENST00000505590.5
ENST00000629236.2
ENST00000508393.5
ENST00000265512.12
alcohol dehydrogenase 4 (class II), pi polypeptide
chr3_-_167474026 0.16 ENST00000466903.1
ENST00000264677.8
serpin family I member 2
chr4_+_87832917 0.16 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
matrix extracellular phosphoglycoprotein
chr2_-_179746040 0.16 ENST00000409343.5
zinc finger protein 385B
chr16_+_69311339 0.16 ENST00000254950.13
vacuolar protein sorting 4 homolog A
chr8_+_98117285 0.15 ENST00000401707.7
ENST00000522319.5
POP1 homolog, ribonuclease P/MRP subunit
chr4_+_7043315 0.15 ENST00000310074.8
ENST00000512388.1
transcriptional adaptor 2B
chr16_+_30658399 0.15 ENST00000356166.11
fibrosin
chr6_+_29170907 0.15 ENST00000641417.1
olfactory receptor family 2 subfamily J member 2
chr3_+_109136707 0.15 ENST00000622536.6
chromosome 3 open reading frame 85
chr10_+_116324440 0.14 ENST00000333254.4
coiled-coil domain containing 172
chr5_-_146182475 0.14 ENST00000674158.1
ENST00000674191.1
ENST00000274562.13
leucyl-tRNA synthetase 1
chr5_+_141484997 0.14 ENST00000617094.1
ENST00000306593.2
ENST00000610539.1
ENST00000618371.4
protocadherin gamma subfamily C, 4
chr6_-_136525961 0.14 ENST00000438100.6
microtubule associated protein 7
chr7_-_44541318 0.14 ENST00000381160.8
NPC1 like intracellular cholesterol transporter 1
chr14_-_56805648 0.14 ENST00000554788.5
ENST00000554845.1
ENST00000408990.8
orthodenticle homeobox 2
chr10_+_84194621 0.14 ENST00000332904.7
cadherin related family member 1
chr19_+_44891206 0.14 ENST00000405636.6
ENST00000252487.9
ENST00000592434.5
ENST00000589649.1
ENST00000426677.7
translocase of outer mitochondrial membrane 40
chr2_-_77522347 0.14 ENST00000409093.1
ENST00000409884.6
ENST00000409088.3
leucine rich repeat transmembrane neuronal 4
chr5_-_127073467 0.14 ENST00000607731.5
ENST00000509733.7
ENST00000296662.10
ENST00000535381.6
chromosome 5 open reading frame 63
chr19_-_10309783 0.13 ENST00000403352.1
ENST00000403903.7
zinc finger GATA like protein 1
chr5_-_146182591 0.13 ENST00000510191.5
ENST00000674277.1
ENST00000674447.1
ENST00000674270.1
ENST00000394434.7
ENST00000674290.1
ENST00000674398.1
ENST00000674174.1
leucyl-tRNA synthetase 1
chr8_+_22567038 0.13 ENST00000523348.1
sorbin and SH3 domain containing 3
chr2_+_168901290 0.13 ENST00000429379.2
ENST00000375363.8
ENST00000421979.1
glucose-6-phosphatase catalytic subunit 2
chr12_-_91179355 0.13 ENST00000550563.5
ENST00000546370.5
decorin
chr17_-_42185452 0.13 ENST00000293330.1
hypocretin neuropeptide precursor
chr14_+_32329256 0.12 ENST00000280979.9
A-kinase anchoring protein 6
chr12_-_16606795 0.12 ENST00000447609.5
LIM domain only 3
chr8_-_86743626 0.12 ENST00000320005.6
cyclic nucleotide gated channel subunit beta 3
chrX_+_78747705 0.12 ENST00000614823.5
ENST00000435339.3
ENST00000514744.5
lysophosphatidic acid receptor 4
chr6_+_131637296 0.12 ENST00000358229.6
ENST00000357639.8
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr6_-_136526177 0.12 ENST00000617204.4
microtubule associated protein 7
chr10_+_47300174 0.12 ENST00000580279.2
growth differentiation factor 10
chr9_+_107306459 0.12 ENST00000457811.1
RAD23 homolog B, nucleotide excision repair protein
chr20_+_43667105 0.11 ENST00000217026.5
MYB proto-oncogene like 2
chr3_+_172754457 0.11 ENST00000441497.6
epithelial cell transforming 2
chr8_+_32646838 0.11 ENST00000651333.1
ENST00000652592.1
neuregulin 1
chr19_-_14835162 0.11 ENST00000322301.5
olfactory receptor family 7 subfamily A member 5
chr3_+_122055355 0.11 ENST00000330540.7
ENST00000469710.5
ENST00000493101.5
CD86 molecule
chr15_-_75455767 0.11 ENST00000360439.8
SIN3 transcription regulator family member A
chr17_-_40755328 0.11 ENST00000312150.5
keratin 25
chr10_+_18400562 0.11 ENST00000377315.5
ENST00000650685.1
calcium voltage-gated channel auxiliary subunit beta 2
chr2_-_212538766 0.11 ENST00000342788.9
erb-b2 receptor tyrosine kinase 4
chr18_+_36544544 0.11 ENST00000591635.5
formin homology 2 domain containing 3
chr16_-_81220370 0.11 ENST00000337114.8
polycystin 1 like 2 (gene/pseudogene)
chr10_+_27532521 0.11 ENST00000683924.1
RAB18, member RAS oncogene family
chr21_-_40847149 0.11 ENST00000400454.6
DS cell adhesion molecule
chr8_-_18887018 0.10 ENST00000523619.5
pleckstrin and Sec7 domain containing 3
chr4_+_87650277 0.10 ENST00000339673.11
ENST00000282479.8
dentin matrix acidic phosphoprotein 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0034769 basement membrane disassembly(GO:0034769)
0.3 1.7 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.3 1.1 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.2 2.7 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.2 1.4 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.2 0.9 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) negative regulation of negative chemotaxis(GO:0050925)
0.2 1.1 GO:0089712 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.2 0.5 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.2 0.5 GO:0061346 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 2.5 GO:0003334 keratinocyte development(GO:0003334)
0.1 1.3 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 0.7 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.3 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 1.0 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.2 GO:0072573 tolerance induction to lipopolysaccharide(GO:0072573)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.4 GO:0061743 motor learning(GO:0061743)
0.1 0.2 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.1 0.2 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.3 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1 0.4 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.3 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.8 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.5 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.5 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 1.4 GO:0030728 ovulation(GO:0030728)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.2 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.5 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.1 GO:0032681 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 1.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.0 1.0 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.3 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.3 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.2 GO:0016078 tRNA catabolic process(GO:0016078)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.6 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0014016 proximal/distal axis specification(GO:0009946) neuroblast differentiation(GO:0014016)
0.0 0.6 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 1.2 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.8 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.0 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.1 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.0 0.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.1 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970) positive regulation of transmission of nerve impulse(GO:0051971)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.5 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.9 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 2.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.2 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.1 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.2 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.6 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.1 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.0 GO:0036021 endolysosome lumen(GO:0036021)
0.2 0.7 GO:0001674 female germ cell nucleus(GO:0001674)
0.2 0.5 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.2 0.5 GO:0060187 cell pole(GO:0060187)
0.1 4.0 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.7 GO:0030478 actin cap(GO:0030478)
0.1 0.9 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 3.3 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.2 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.2 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 1.3 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.0 GO:0005771 multivesicular body(GO:0005771)
0.0 0.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.6 GO:0031258 lamellipodium membrane(GO:0031258)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.5 2.7 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 1.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.2 1.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2 2.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.7 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.5 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 0.7 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1 2.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.9 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.5 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 3.0 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.3 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 1.6 GO:0031489 myosin V binding(GO:0031489)
0.0 1.0 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 1.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 1.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0035276 ethanol binding(GO:0035276)
0.0 0.1 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.0 0.2 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.6 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.2 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.7 GO:0005549 odorant binding(GO:0005549)
0.0 0.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0033265 choline binding(GO:0033265)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.7 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 2.7 GO:0005179 hormone activity(GO:0005179)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.2 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.0 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.0 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 1.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.3 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.7 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162) microtubule plus-end binding(GO:0051010)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.8 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.5 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 4.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.7 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.5 PID GLYPICAN 1PATHWAY Glypican 1 network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.0 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 0.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 2.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.1 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 1.9 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation