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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for MAFA

Z-value: 0.43

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Transcription factors associated with MAFA

Gene Symbol Gene ID Gene Info
MAFA
ENSG00000182759.4 MAFA

Activity profile of MAFA motif

Sorted Z-values of MAFA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MAFA

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr7_-_151057880 0.84 ENST00000485972.6
CDK5
cyclin dependent kinase 5
chr7_-_151057848 0.83 ENST00000297518.4
CDK5
cyclin dependent kinase 5
chr7_-_22194709 0.79 ENST00000458533.5
RAPGEF5
Rap guanine nucleotide exchange factor 5
chr20_-_59007807 0.75 ENST00000680386.1
CTSZ
cathepsin Z
chr1_+_153775357 0.60 ENST00000624995.4
SLC27A3
solute carrier family 27 member 3
chr13_-_113864062 0.54 ENST00000327773.7
GAS6
growth arrest specific 6
chr22_+_22818994 0.51 ENST00000390316.2
IGLV3-9
immunoglobulin lambda variable 3-9
chr17_+_63477052 0.43 ENST00000290866.10
ENST00000428043.5
ACE
angiotensin I converting enzyme
chrX_+_10015226 0.40 ENST00000380861.9
WWC3
WWC family member 3
chr12_-_5945252 0.38 ENST00000546188.5
ENST00000682330.1
ANO2
anoctamin 2
chr4_+_73740541 0.38 ENST00000401931.1
ENST00000307407.8
CXCL8
C-X-C motif chemokine ligand 8
chr12_-_5945216 0.38 ENST00000650848.1
ANO2
anoctamin 2
chr6_+_42929127 0.36 ENST00000394142.7
CNPY3
canopy FGF signaling regulator 3
chr20_-_23086316 0.34 ENST00000246006.5
CD93
CD93 molecule
chr19_+_35031263 0.33 ENST00000640135.1
ENST00000596348.2
SCN1B
sodium voltage-gated channel beta subunit 1
chr7_+_129126518 0.32 ENST00000467614.2
ENSG00000230626.4
novel protein similar to mitogen-activated protein kinase kinase 2 MAP2K2
chr22_-_26618026 0.31 ENST00000647684.1
CRYBB1
crystallin beta B1
chr10_-_77637633 0.31 ENST00000638223.1
ENST00000639544.1
ENST00000640807.1
ENST00000434208.6
ENST00000626620.3
ENST00000638575.1
ENST00000638759.1
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
chr9_+_94726657 0.31 ENST00000375315.8
ENST00000277198.6
ENST00000297979.9
AOPEP
aminopeptidase O (putative)
chr21_+_44600597 0.30 ENST00000609664.2
KRTAP10-7
keratin associated protein 10-7
chr16_-_46831134 0.29 ENST00000394806.6
ENST00000285697.9
C16orf87
chromosome 16 open reading frame 87
chr8_-_88327475 0.28 ENST00000286614.11
MMP16
matrix metallopeptidase 16
chr9_+_122371014 0.27 ENST00000362012.7
PTGS1
prostaglandin-endoperoxide synthase 1
chr7_-_108528155 0.25 ENST00000453085.1
PNPLA8
patatin like phospholipase domain containing 8
chr2_-_25982471 0.24 ENST00000264712.8
KIF3C
kinesin family member 3C
chr12_+_56152579 0.23 ENST00000551834.5
ENST00000552568.5
MYL6B
myosin light chain 6B
chr1_+_65992389 0.23 ENST00000423207.6
PDE4B
phosphodiesterase 4B
chr17_-_78132407 0.22 ENST00000322914.7
TMC6
transmembrane channel like 6
chr3_+_196712298 0.20 ENST00000392391.9
ENST00000296333.10
PIGX
phosphatidylinositol glycan anchor biosynthesis class X
chr3_-_48717166 0.19 ENST00000413654.5
ENST00000454335.5
ENST00000440424.5
ENST00000449610.5
ENST00000443964.1
ENST00000417896.1
ENST00000413298.5
ENST00000449563.5
ENST00000443853.5
ENST00000437427.5
ENST00000446860.5
ENST00000412850.5
ENST00000424035.1
ENST00000340879.8
ENST00000431721.6
ENST00000434860.1
ENST00000328631.10
ENST00000432678.6
IP6K2
inositol hexakisphosphate kinase 2
chr17_+_41105332 0.19 ENST00000391415.1
ENST00000617453.1
KRTAP4-9
keratin associated protein 4-9
chr3_+_141402322 0.18 ENST00000510338.5
ENST00000504673.5
ZBTB38
zinc finger and BTB domain containing 38
chr2_+_85584402 0.17 ENST00000306384.5
VAMP5
vesicle associated membrane protein 5
chr22_+_22375984 0.16 ENST00000390296.2
IGLV5-45
immunoglobulin lambda variable 5-45
chr4_-_151015263 0.15 ENST00000510413.5
ENST00000507224.5
ENST00000651943.2
LRBA
LPS responsive beige-like anchor protein
chr7_+_152025632 0.14 ENST00000430044.7
ENST00000431668.1
ENST00000446096.5
ENST00000423337.5
GALNT11
polypeptide N-acetylgalactosaminyltransferase 11
chr5_+_139293660 0.14 ENST00000512876.5
ENST00000513678.5
MATR3
matrin 3
chr9_-_28670285 0.14 ENST00000379992.6
ENST00000308675.5
ENST00000613945.3
LINGO2
leucine rich repeat and Ig domain containing 2
chr9_+_122371036 0.14 ENST00000619306.5
ENST00000426608.6
ENST00000223423.8
PTGS1
prostaglandin-endoperoxide synthase 1
chr2_+_53971072 0.14 ENST00000422521.2
ENST00000607452.6
ACYP2
acylphosphatase 2
chr15_-_89912882 0.13 ENST00000398333.7
ENST00000357484.10
ARPIN-AP3S2
ARPIN
ARPIN-AP3S2 readthrough
actin related protein 2/3 complex inhibitor
chr5_+_139293939 0.13 ENST00000508689.1
ENST00000514528.5
MATR3
matrin 3
chr21_+_43169008 0.13 ENST00000291554.6
CRYAA
crystallin alpha A
chr7_+_74657745 0.13 ENST00000614986.4
ENST00000620879.4
ENST00000621734.4
GTF2I
general transcription factor IIi
chr6_-_143511682 0.13 ENST00000002165.11
FUCA2
alpha-L-fucosidase 2
chrX_-_53281524 0.12 ENST00000498281.2
IQSEC2
IQ motif and Sec7 domain ArfGEF 2
chr2_+_114442616 0.11 ENST00000410059.6
DPP10
dipeptidyl peptidase like 10
chr5_-_22853320 0.11 ENST00000504376.6
ENST00000382254.6
CDH12
cadherin 12
chr8_+_23288081 0.11 ENST00000265806.12
ENST00000519952.6
ENST00000518840.6
R3HCC1
R3H domain and coiled-coil containing 1
chr17_-_41572052 0.11 ENST00000588431.1
ENST00000246662.9
KRT9
keratin 9
chr4_-_151015713 0.10 ENST00000357115.9
LRBA
LPS responsive beige-like anchor protein
chrX_-_53281566 0.10 ENST00000638583.1
ENST00000639161.2
ENST00000485377.5
IQSEC2
IQ motif and Sec7 domain ArfGEF 2
chr12_+_132144417 0.10 ENST00000330579.6
NOC4L
nucleolar complex associated 4 homolog
chr20_+_325536 0.10 ENST00000342665.5
SOX12
SRY-box transcription factor 12
chr2_+_190880809 0.09 ENST00000320717.8
GLS
glutaminase
chr14_+_50312311 0.09 ENST00000426751.7
ENST00000311459.12
ENST00000672419.1
ENST00000672910.1
ENST00000557421.7
ENST00000245448.11
ENST00000554204.7
DMAC2L
distal membrane arm assembly complex 2 like
chr1_-_153544997 0.09 ENST00000368715.5
S100A4
S100 calcium binding protein A4
chr10_+_119207560 0.09 ENST00000392870.3
GRK5
G protein-coupled receptor kinase 5
chrX_-_66639022 0.09 ENST00000374719.8
EDA2R
ectodysplasin A2 receptor
chr7_-_22500152 0.09 ENST00000406890.6
ENST00000678116.1
ENST00000424363.5
STEAP1B
STEAP family member 1B
chr6_+_33277117 0.09 ENST00000451237.3
B3GALT4
beta-1,3-galactosyltransferase 4
chrX_-_66639255 0.08 ENST00000451436.6
EDA2R
ectodysplasin A2 receptor
chr5_+_140360187 0.08 ENST00000506757.7
ENST00000506545.5
ENST00000432095.6
ENST00000507527.1
SLC4A9
solute carrier family 4 member 9
chr17_-_3433841 0.08 ENST00000248384.1
OR1E2
olfactory receptor family 1 subfamily E member 2
chr1_+_42767241 0.08 ENST00000372525.7
C1orf50
chromosome 1 open reading frame 50
chr12_-_1918473 0.08 ENST00000586184.5
ENST00000587995.5
ENST00000585732.1
CACNA2D4
calcium voltage-gated channel auxiliary subunit alpha2delta 4
chr1_+_224616302 0.08 ENST00000272133.4
CNIH3
cornichon family AMPA receptor auxiliary protein 3
chr19_-_4124082 0.08 ENST00000394867.8
ENST00000262948.10
MAP2K2
mitogen-activated protein kinase kinase 2
chr1_+_75724431 0.07 ENST00000541113.6
ENST00000680805.1
ACADM
acyl-CoA dehydrogenase medium chain
chr6_-_99349647 0.07 ENST00000389677.6
FAXC
failed axon connections homolog, metaxin like GST domain containing
chr9_+_124853417 0.07 ENST00000613760.4
ENST00000618744.4
ENST00000373574.2
WDR38
WD repeat domain 38
chr1_+_75724597 0.07 ENST00000681790.1
ACADM
acyl-CoA dehydrogenase medium chain
chr19_-_42594918 0.07 ENST00000244336.10
CEACAM8
CEA cell adhesion molecule 8
chr10_-_77637558 0.07 ENST00000372421.10
ENST00000639370.1
ENST00000640773.1
ENST00000638895.1
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
chr16_+_1309136 0.07 ENST00000325437.9
UBE2I
ubiquitin conjugating enzyme E2 I
chr14_+_90397019 0.07 ENST00000447653.8
ENST00000356978.9
ENST00000626705.2
CALM1
calmodulin 1
chr11_-_70662197 0.06 ENST00000409161.5
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr10_+_25174969 0.06 ENST00000376351.4
GPR158
G protein-coupled receptor 158
chr1_+_75724672 0.06 ENST00000370834.9
ENST00000370841.9
ENST00000679687.1
ENST00000420607.6
ACADM
acyl-CoA dehydrogenase medium chain
chr3_-_126558926 0.06 ENST00000318225.3
C3orf22
chromosome 3 open reading frame 22
chr10_+_25174796 0.06 ENST00000650135.1
GPR158
G protein-coupled receptor 158
chr8_-_113377125 0.06 ENST00000343508.7
CSMD3
CUB and Sushi multiple domains 3
chr9_-_129620743 0.06 ENST00000619117.1
ENST00000372478.4
C9orf50
chromosome 9 open reading frame 50
chr9_-_128127711 0.05 ENST00000449878.1
ENST00000338961.11
ENST00000678174.1
PTGES2
prostaglandin E synthase 2
chr5_+_139293728 0.05 ENST00000510056.5
ENST00000511249.5
ENST00000394805.8
ENST00000503811.5
ENST00000618441.5
MATR3
matrin 3
chr5_+_177426701 0.05 ENST00000507633.5
ENST00000393576.7
ENST00000355958.9
ENST00000528793.5
ENST00000512684.1
GRK6
G protein-coupled receptor kinase 6
chr1_+_158355894 0.05 ENST00000368162.2
CD1E
CD1e molecule
chr10_-_100529854 0.05 ENST00000370320.4
ENST00000299166.9
ENST00000370322.5
NDUFB8
NADH:ubiquinone oxidoreductase subunit B8
chr20_-_45115149 0.05 ENST00000307971.7
ENST00000372789.5
WFDC5
WAP four-disulfide core domain 5
chr3_-_49786508 0.05 ENST00000395238.5
ENST00000468463.5
ENST00000321599.9
ENST00000460540.1
IP6K1
inositol hexakisphosphate kinase 1
chr11_+_107591077 0.05 ENST00000531234.5
ENST00000265840.12
ELMOD1
ELMO domain containing 1
chr16_-_67481079 0.05 ENST00000565835.5
ENST00000602876.5
ENST00000540149.5
ATP6V0D1
ATPase H+ transporting V0 subunit d1
chr1_-_45491150 0.05 ENST00000372086.4
TESK2
testis associated actin remodelling kinase 2
chr3_+_131381671 0.05 ENST00000537561.5
ENST00000521288.2
ENST00000502852.1
NUDT16
nudix hydrolase 16
chr5_-_179858797 0.05 ENST00000520698.5
ENST00000518235.5
ENST00000376931.6
ENST00000518219.5
ENST00000292586.11
ENST00000521333.5
ENST00000523084.5
MRNIP
MRN complex interacting protein
chr4_+_6782674 0.05 ENST00000307659.6
ENST00000425103.5
KIAA0232
KIAA0232
chr2_-_53970985 0.05 ENST00000404125.6
PSME4
proteasome activator subunit 4
chr21_+_39867387 0.05 ENST00000328619.10
PCP4
Purkinje cell protein 4
chr1_+_156154371 0.05 ENST00000368282.1
SEMA4A
semaphorin 4A
chr1_-_216805367 0.04 ENST00000360012.7
ESRRG
estrogen related receptor gamma
chr1_+_163069353 0.04 ENST00000531057.5
ENST00000527809.5
ENST00000367908.8
ENST00000367909.11
RGS4
regulator of G protein signaling 4
chr7_-_149126306 0.04 ENST00000483014.1
ENST00000378061.7
ZNF425
zinc finger protein 425
chr22_+_22244776 0.04 ENST00000302273.2
ENST00000403807.4
VPREB1
V-set pre-B cell surrogate light chain 1
chr20_+_2692736 0.04 ENST00000380648.9
ENST00000497450.5
EBF4
EBF family member 4
chr9_+_2621766 0.04 ENST00000382100.8
VLDLR
very low density lipoprotein receptor
chr3_-_49786194 0.04 ENST00000613416.4
IP6K1
inositol hexakisphosphate kinase 1
chr9_+_2622053 0.04 ENST00000681306.1
ENST00000681618.1
VLDLR
very low density lipoprotein receptor
chr4_-_47837949 0.04 ENST00000505909.5
ENST00000273857.9
ENST00000502252.5
CORIN
corin, serine peptidase
chr4_+_2469068 0.03 ENST00000541204.5
ENST00000502316.5
ENST00000507247.5
ENST00000509258.5
ENST00000314289.13
ENST00000511859.5
RNF4
ring finger protein 4
chr15_-_66565959 0.03 ENST00000537670.5
LCTL
lactase like
chr9_+_2621556 0.03 ENST00000680746.1
VLDLR
very low density lipoprotein receptor
chr5_+_177086867 0.03 ENST00000503708.5
ENST00000393648.6
ENST00000514472.1
ENST00000502906.5
ENST00000292408.9
ENST00000510911.5
FGFR4
fibroblast growth factor receptor 4
chr7_-_135211313 0.03 ENST00000682802.1
ENST00000683848.1
ENST00000354475.5
WDR91
WD repeat domain 91
chr1_-_190477854 0.03 ENST00000367462.5
BRINP3
BMP/retinoic acid inducible neural specific 3
chr20_-_33004307 0.03 ENST00000420875.5
ENST00000375519.2
ENST00000375523.7
ENST00000356173.8
SUN5
Sad1 and UNC84 domain containing 5
chr5_+_139293700 0.03 ENST00000504045.5
ENST00000504311.5
ENST00000502499.5
MATR3
matrin 3
chr6_-_24489565 0.03 ENST00000230036.2
GPLD1
glycosylphosphatidylinositol specific phospholipase D1
chr17_-_49848017 0.03 ENST00000326219.5
ENST00000334568.8
ENST00000352793.6
ENST00000398154.5
ENST00000436235.5
TAC4
tachykinin precursor 4
chr16_-_67481131 0.03 ENST00000290949.8
ATP6V0D1
ATPase H+ transporting V0 subunit d1
chr19_+_35269065 0.02 ENST00000595068.5
ENST00000379134.7
ENST00000594064.5
ENST00000598058.1
USF2
upstream transcription factor 2, c-fos interacting
chr6_+_32024278 0.02 ENST00000647698.1
C4B
complement C4B (Chido blood group)
chr2_+_118088432 0.02 ENST00000245787.9
INSIG2
insulin induced gene 2
chr12_-_122730828 0.02 ENST00000432564.3
HCAR1
hydroxycarboxylic acid receptor 1
chr1_+_77888612 0.02 ENST00000334785.12
NEXN
nexilin F-actin binding protein
chr1_+_77888490 0.02 ENST00000401035.7
ENST00000330010.12
NEXN
nexilin F-actin binding protein
chr5_-_39270623 0.02 ENST00000512138.1
ENST00000646045.2
FYB1
FYN binding protein 1
chr22_-_30266839 0.01 ENST00000403463.1
ENST00000215781.3
OSM
oncostatin M
chr12_-_132144302 0.01 ENST00000397333.4
DDX51
DEAD-box helicase 51
chr19_+_35612729 0.01 ENST00000203166.10
HAUS5
HAUS augmin like complex subunit 5
chr6_-_73521783 0.01 ENST00000331523.7
ENST00000356303.7
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr1_-_153312919 0.01 ENST00000683862.1
PGLYRP3
peptidoglycan recognition protein 3
chr14_+_90397056 0.01 ENST00000553542.5
CALM1
calmodulin 1
chr11_-_63015804 0.01 ENST00000535878.5
ENST00000545207.5
SLC22A8
solute carrier family 22 member 8
chrX_-_93673558 0.00 ENST00000475430.2
ENST00000373079.4
NAP1L3
nucleosome assembly protein 1 like 3
chr3_+_184299198 0.00 ENST00000417952.5
ENST00000310118.9
PSMD2
proteasome 26S subunit, non-ATPase 2
chr19_+_35666515 0.00 ENST00000617999.4
ENST00000616789.4
UPK1A
uroplakin 1A
chr12_+_108131740 0.00 ENST00000332082.8
WSCD2
WSC domain containing 2
chr7_-_99919479 0.00 ENST00000354241.5
TRIM4
tripartite motif containing 4
chr17_+_43211835 0.00 ENST00000588693.5
ENST00000588659.5
ENST00000541594.5
ENST00000536052.5
ENST00000612339.4
TMEM106A
transmembrane protein 106A

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 0.5 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.1 0.8 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.4 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.1 0.2 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 0.2 GO:0051793 medium-chain fatty acid catabolic process(GO:0051793)
0.1 0.3 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.0 0.5 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:1903755 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.0 0.0 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.0 0.3 GO:0002003 angiotensin maturation(GO:0002003)
0.0 0.2 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.1 GO:0034436 glycoprotein transport(GO:0034436)
0.0 0.1 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.0 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.0 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.3 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.1 GO:0090170 regulation of Golgi inheritance(GO:0090170)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0030689 Noc complex(GO:0030689)
0.0 0.1 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.8 GO:0099738 cell cortex region(GO:0099738)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.1 0.4 GO:0008241 tripeptidyl-peptidase activity(GO:0008240) peptidyl-dipeptidase activity(GO:0008241) bradykinin receptor binding(GO:0031711) metallodipeptidase activity(GO:0070573)
0.1 0.4 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.3 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1 0.3 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.8 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.2 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.0 0.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.5 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 0.1 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.8 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis