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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for MBD2

Z-value: 0.79

Motif logo

Transcription factors associated with MBD2

Gene Symbol Gene ID Gene Info
ENSG00000134046.12 MBD2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MBD2hg38_v1_chr18_-_54224578_542246890.019.8e-01Click!

Activity profile of MBD2 motif

Sorted Z-values of MBD2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MBD2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr17_+_67825664 3.40 ENST00000321892.8
bromodomain PHD finger transcription factor
chr17_+_67825494 3.32 ENST00000306378.11
ENST00000544778.6
bromodomain PHD finger transcription factor
chr18_-_25352116 2.26 ENST00000584787.5
ENST00000538137.6
ENST00000361524.8
zinc finger protein 521
chr1_+_81800906 2.20 ENST00000674393.1
ENST00000674208.1
adhesion G protein-coupled receptor L2
chr8_+_37796850 2.14 ENST00000412232.3
adhesion G protein-coupled receptor A2
chr8_+_37796906 2.08 ENST00000315215.11
adhesion G protein-coupled receptor A2
chr8_-_28386073 2.01 ENST00000523095.5
ENST00000522795.1
zinc finger protein 395
chr3_-_18424533 1.89 ENST00000417717.6
SATB homeobox 1
chr8_-_28386417 1.83 ENST00000521185.5
ENST00000520290.5
ENST00000344423.10
zinc finger protein 395
chr1_-_154502402 1.74 ENST00000304760.3
Src homology 2 domain containing E
chr17_-_64919456 1.68 ENST00000339474.9
ENST00000584306.6
ENST00000581368.5
leucine rich repeat containing 37 member A3
chr1_+_81800368 1.64 ENST00000674489.1
ENST00000674442.1
ENST00000674419.1
ENST00000674407.1
ENST00000674168.1
ENST00000674307.1
ENST00000674209.1
ENST00000370715.5
ENST00000370713.5
ENST00000319517.10
ENST00000627151.2
ENST00000370717.6
adhesion G protein-coupled receptor L2
chr19_-_14090695 1.57 ENST00000533683.7
sterile alpha motif domain containing 1
chr14_+_52553273 1.55 ENST00000542169.6
ENST00000555622.1
G protein-coupled receptor 137C
chr14_+_52552830 1.52 ENST00000321662.11
G protein-coupled receptor 137C
chr12_+_19129779 1.49 ENST00000539256.5
ENST00000299275.10
ENST00000538714.5
pleckstrin homology domain containing A5
chr9_+_136712531 1.44 ENST00000371692.9
divergent protein kinase domain 1B
chr4_-_25862979 1.42 ENST00000399878.8
SEL1L family member 3
chr12_+_27244222 1.40 ENST00000545470.5
ENST00000389032.8
ENST00000540996.5
serine/threonine kinase 38 like
chr15_-_68820861 1.38 ENST00000560303.1
ENST00000465139.6
acidic nuclear phosphoprotein 32 family member A
chr1_+_6785518 1.27 ENST00000467404.6
calmodulin binding transcription activator 1
chr6_+_37353972 1.17 ENST00000373479.9
ring finger protein 8
chr3_+_37861926 1.16 ENST00000443503.6
CTD small phosphatase like
chr11_+_44726811 1.16 ENST00000533202.5
ENST00000520358.7
ENST00000533080.5
ENST00000520999.6
tetraspanin 18
chr6_+_15248855 1.16 ENST00000397311.4
jumonji and AT-rich interaction domain containing 2
chr15_-_64775574 1.14 ENST00000300069.5
RNA binding protein, mRNA processing factor 2
chr3_-_125055987 1.14 ENST00000311127.9
heart development protein with EGF like domains 1
chr11_-_2139382 1.14 ENST00000416167.7
insulin like growth factor 2
chr6_-_16761447 1.12 ENST00000244769.8
ENST00000436367.6
ataxin 1
chr3_-_18425295 1.09 ENST00000338745.11
ENST00000450898.1
SATB homeobox 1
chr7_-_28958321 1.07 ENST00000539664.3
TLR4 interactor with leucine rich repeats
chr18_-_55588535 1.06 ENST00000566286.5
ENST00000566279.5
ENST00000626595.2
ENST00000564999.5
ENST00000616053.4
ENST00000356073.8
transcription factor 4
chr2_+_47403116 1.06 ENST00000645506.1
ENST00000406134.5
ENST00000233146.7
mutS homolog 2
chr1_+_108560031 1.04 ENST00000405454.1
ENST00000370035.8
family with sequence similarity 102 member B
chr11_-_75525925 1.03 ENST00000336898.8
glycerophosphodiester phosphodiesterase domain containing 5
chr11_+_74748831 1.01 ENST00000299563.5
ring finger protein 169
chr11_-_89491131 1.00 ENST00000343727.9
ENST00000531342.5
ENST00000375979.7
NADPH oxidase 4
chr1_+_84078043 0.97 ENST00000370689.6
ENST00000370688.7
protein kinase cAMP-activated catalytic subunit beta
chr2_+_42048012 0.96 ENST00000294964.6
protein kinase domain containing, cytoplasmic
chr5_-_180649613 0.94 ENST00000393347.7
ENST00000619105.4
fms related receptor tyrosine kinase 4
chr19_-_11262499 0.94 ENST00000294618.12
dedicator of cytokinesis 6
chr14_-_89417148 0.93 ENST00000557258.6
forkhead box N3
chr11_-_89491320 0.92 ENST00000534731.5
ENST00000527626.5
ENST00000525196.5
ENST00000263317.9
NADPH oxidase 4
chr10_+_128047559 0.90 ENST00000306042.9
protein tyrosine phosphatase receptor type E
chrX_-_63755187 0.90 ENST00000635729.1
ENST00000623566.3
Cdc42 guanine nucleotide exchange factor 9
chr13_+_20703677 0.89 ENST00000682841.1
interleukin 17D
chrX_-_63754664 0.88 ENST00000677315.1
ENST00000636392.1
ENST00000637040.1
ENST00000637178.1
ENST00000637557.1
ENST00000636048.1
ENST00000638021.1
ENST00000672513.1
novel protein
Cdc42 guanine nucleotide exchange factor 9
chr10_-_124744280 0.88 ENST00000337318.8
family with sequence similarity 53 member B
chr20_-_48827992 0.88 ENST00000371941.4
phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1
chr9_+_87498491 0.87 ENST00000622514.4
death associated protein kinase 1
chr22_+_24952705 0.87 ENST00000358431.8
KIAA1671
chrX_-_63755032 0.86 ENST00000624538.2
ENST00000636276.1
ENST00000624843.3
ENST00000671907.1
ENST00000624210.3
ENST00000374870.8
ENST00000635967.1
ENST00000253401.10
ENST00000672194.1
ENST00000637723.2
ENST00000637417.1
ENST00000637520.1
ENST00000374872.4
ENST00000636926.1
Cdc42 guanine nucleotide exchange factor 9
chr19_-_14090963 0.83 ENST00000269724.5
sterile alpha motif domain containing 1
chr19_-_18940289 0.83 ENST00000542541.6
ENST00000433218.6
homer scaffold protein 3
chr6_+_89433164 0.81 ENST00000369408.9
ENST00000447838.6
ankyrin repeat domain 6
chr18_-_55588184 0.80 ENST00000354452.8
ENST00000565908.6
ENST00000635822.2
transcription factor 4
chr5_-_180649579 0.80 ENST00000261937.11
ENST00000502649.5
fms related receptor tyrosine kinase 4
chr19_+_39413528 0.79 ENST00000438123.5
ENST00000409797.6
ENST00000451354.6
pleckstrin homology and RhoGEF domain containing G2
chr19_-_42255119 0.79 ENST00000222329.9
ENST00000594664.1
ETS2 repressor factor
novel protein
chr1_+_154502207 0.79 ENST00000368482.8
tudor domain containing 10
chr19_-_17245889 0.78 ENST00000291442.4
nuclear receptor subfamily 2 group F member 6
chr18_+_79395856 0.78 ENST00000253506.9
ENST00000591814.5
ENST00000427363.7
nuclear factor of activated T cells 1
chr16_-_89720861 0.78 ENST00000389386.8
VPS9 domain containing 1
chr17_+_19648723 0.77 ENST00000672357.1
ENST00000584332.6
ENST00000176643.11
ENST00000339618.8
ENST00000579855.5
ENST00000671878.1
ENST00000395575.7
aldehyde dehydrogenase 3 family member A2
chr16_-_49856105 0.76 ENST00000563137.7
zinc finger protein 423
chr6_+_89433127 0.74 ENST00000339746.9
ankyrin repeat domain 6
chr11_-_27700472 0.74 ENST00000418212.5
ENST00000533246.5
brain derived neurotrophic factor
chr19_-_11197516 0.73 ENST00000592903.5
ENST00000586659.6
ENST00000589359.5
ENST00000588724.5
KN motif and ankyrin repeat domains 2
chr8_-_51899002 0.73 ENST00000522514.6
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr2_+_180980347 0.73 ENST00000602959.5
ENST00000602479.5
ENST00000392415.6
ENST00000602291.5
ubiquitin conjugating enzyme E2 E3
chr11_-_27700447 0.73 ENST00000356660.9
brain derived neurotrophic factor
chr1_+_33256479 0.70 ENST00000539719.6
ENST00000483388.5
zinc finger protein 362
chr2_+_10911924 0.70 ENST00000295082.3
potassium voltage-gated channel modifier subfamily F member 1
chr2_+_45651650 0.69 ENST00000306156.8
protein kinase C epsilon
chr12_-_57430778 0.69 ENST00000448732.1
ENST00000634871.1
R3H domain containing 2
chr12_-_57430956 0.68 ENST00000347140.7
ENST00000402412.5
R3H domain containing 2
chr18_+_79395942 0.68 ENST00000397790.6
nuclear factor of activated T cells 1
chr13_-_28495079 0.68 ENST00000615840.4
ENST00000282397.9
ENST00000541932.5
ENST00000539099.1
ENST00000639477.1
fms related receptor tyrosine kinase 1
chr5_+_123512214 0.67 ENST00000511130.6
ENST00000512718.7
casein kinase 1 gamma 3
chr6_+_37354046 0.67 ENST00000487950.1
ENST00000469731.5
ring finger protein 8
chr3_-_185825029 0.66 ENST00000382199.7
insulin like growth factor 2 mRNA binding protein 2
chr19_+_35000426 0.66 ENST00000411896.6
ENST00000424536.2
GRAM domain containing 1A
chr9_-_127854636 0.65 ENST00000344849.4
ENST00000373203.9
endoglin
chr3_-_128487916 0.65 ENST00000430265.6
GATA binding protein 2
chr3_-_185824966 0.64 ENST00000457616.6
ENST00000346192.7
insulin like growth factor 2 mRNA binding protein 2
chr18_-_36828771 0.63 ENST00000589049.5
ENST00000587129.5
ENST00000590842.5
tubulin polyglutamylase complex subunit 2
chr11_-_63768762 0.63 ENST00000433688.2
chromosome 11 open reading frame 95
chrX_-_54496212 0.63 ENST00000375135.4
FYVE, RhoGEF and PH domain containing 1
chr4_-_77819356 0.62 ENST00000649644.1
ENST00000504123.6
ENST00000515441.2
CCR4-NOT transcription complex subunit 6 like
chr22_+_19714450 0.62 ENST00000455784.7
ENST00000406395.5
septin 5
chr17_+_19648915 0.62 ENST00000672567.1
ENST00000672709.1
aldehyde dehydrogenase 3 family member A2
chr19_+_35000275 0.62 ENST00000317991.10
ENST00000680623.1
GRAM domain containing 1A
chr17_-_28951285 0.62 ENST00000577226.5
PHD finger protein 12
chr16_+_2969270 0.61 ENST00000293978.12
progestin and adipoQ receptor family member 4
chr16_+_2969307 0.61 ENST00000576565.1
ENST00000318782.9
progestin and adipoQ receptor family member 4
chr18_-_36829154 0.61 ENST00000614939.4
ENST00000610723.4
tubulin polyglutamylase complex subunit 2
chr4_+_26860778 0.61 ENST00000467011.6
stromal interaction molecule 2
chr16_+_2969548 0.60 ENST00000572687.1
progestin and adipoQ receptor family member 4
chr2_+_216633411 0.60 ENST00000233809.9
insulin like growth factor binding protein 2
chr11_-_47176851 0.60 ENST00000629231.2
ENST00000526342.5
ENST00000528444.5
ENST00000530596.5
ENST00000525398.5
ENST00000524782.6
ENST00000527927.5
ENST00000525314.5
ADP ribosylation factor GTPase activating protein 2
chr3_-_184017863 0.60 ENST00000427120.6
ENST00000334444.11
ENST00000392579.6
ENST00000382494.6
ENST00000265586.10
ENST00000446941.2
ATP binding cassette subfamily C member 5
chr12_+_57089094 0.59 ENST00000342556.6
ENST00000300131.8
NGFI-A binding protein 2
chr12_+_52948840 0.58 ENST00000388837.6
ENST00000550600.5
keratin 18
chr6_+_2765361 0.58 ENST00000380773.9
ENST00000380771.8
ENST00000618555.4
WRN helicase interacting protein 1
chr7_+_69599588 0.58 ENST00000403018.3
activator of transcription and developmental regulator AUTS2
chr11_+_123430259 0.57 ENST00000533341.3
ENST00000635736.2
GRAM domain containing 1B
chr1_+_215567279 0.57 ENST00000259154.9
potassium channel tetramerization domain containing 3
chr20_+_325536 0.56 ENST00000342665.5
SRY-box transcription factor 12
chr18_-_812230 0.56 ENST00000314574.5
YES proto-oncogene 1, Src family tyrosine kinase
chr3_+_33114007 0.56 ENST00000320954.11
cartilage associated protein
chr2_-_53786916 0.55 ENST00000406687.5
ENST00000263634.8
ENST00000394717.3
ankyrin repeat and SOCS box containing 3
chr17_-_48613468 0.54 ENST00000498634.2
homeobox B8
chr17_-_63842663 0.54 ENST00000613943.4
ENST00000448276.7
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr9_+_128068172 0.54 ENST00000373068.6
ENST00000373069.10
solute carrier family 25 member 25
chr13_+_34942263 0.53 ENST00000379939.7
ENST00000400445.7
neurobeachin
chr11_-_119340544 0.53 ENST00000530681.2
C1q and TNF related 5
chr1_+_109466527 0.53 ENST00000369872.4
synaptophysin like 2
chr2_+_180980566 0.53 ENST00000410062.9
ubiquitin conjugating enzyme E2 E3
chr1_+_52142044 0.52 ENST00000287727.8
ENST00000371591.2
zinc finger FYVE-type containing 9
chr10_-_102120246 0.51 ENST00000425280.2
LIM domain binding 1
chr18_-_812516 0.51 ENST00000584307.5
YES proto-oncogene 1, Src family tyrosine kinase
chr17_+_19648792 0.50 ENST00000630662.2
aldehyde dehydrogenase 3 family member A2
chr11_-_117098415 0.50 ENST00000445177.6
ENST00000375300.6
ENST00000446921.6
SIK family kinase 3
chr17_+_56593685 0.49 ENST00000332822.6
noggin
chr4_+_26860809 0.49 ENST00000465503.6
ENST00000467087.7
stromal interaction molecule 2
chr17_+_40121955 0.49 ENST00000398532.9
MSL complex subunit 1
chr7_+_87152531 0.49 ENST00000432366.6
ENST00000423590.6
ENST00000394703.9
cyclin D binding myb like transcription factor 1
chr17_+_76868396 0.48 ENST00000569840.7
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B
chr2_+_112275588 0.48 ENST00000409871.6
ENST00000343936.4
zinc finger CCCH-type containing 6
chr5_+_168529299 0.47 ENST00000338333.5
fibrillarin like 1
chr1_-_6485433 0.47 ENST00000535355.6
pleckstrin homology and RhoGEF domain containing G5
chr8_-_73746830 0.47 ENST00000524300.6
ENST00000523558.5
ENST00000521210.5
ENST00000355780.9
ENST00000524104.5
ENST00000521736.5
ENST00000521447.5
ENST00000517542.5
ENST00000521451.5
ENST00000521419.5
ENST00000518502.5
staufen double-stranded RNA binding protein 2
chr10_+_23439060 0.47 ENST00000376495.5
OTU deubiquitinase 1
chr16_+_58025745 0.47 ENST00000219271.4
matrix metallopeptidase 15
chr11_+_43358908 0.47 ENST00000039989.9
ENST00000299240.10
tetratricopeptide repeat domain 17
chr12_-_57006476 0.47 ENST00000300101.3
zinc finger and BTB domain containing 39
chr13_-_80341100 0.46 ENST00000377104.4
sprouty RTK signaling antagonist 2
chr17_-_28951443 0.46 ENST00000268756.7
ENST00000332830.9
ENST00000584685.1
PHD finger protein 12
chr7_+_87152409 0.46 ENST00000413276.6
ENST00000446796.6
ENST00000420131.5
ENST00000414630.6
ENST00000453049.5
ENST00000428819.5
ENST00000448598.5
ENST00000449088.7
ENST00000430405.7
ENST00000331242.12
cyclin D binding myb like transcription factor 1
chr4_-_6472548 0.46 ENST00000382599.9
protein phosphatase 2 regulatory subunit Bgamma
chr17_+_29593118 0.45 ENST00000394859.8
ankyrin repeat domain 13B
chr1_-_46719074 0.45 ENST00000371933.8
ENST00000672422.2
ENST00000674263.1
ENST00000674415.1
ENST00000674435.1
EF-hand calcium binding domain 14
chr17_+_75525682 0.45 ENST00000392550.8
ENST00000167462.9
ENST00000375227.8
ENST00000578363.5
ENST00000579392.5
LLGL scribble cell polarity complex component 2
chr4_-_16226460 0.44 ENST00000405303.7
transmembrane anterior posterior transformation 1
chr18_+_7567266 0.44 ENST00000580170.6
protein tyrosine phosphatase receptor type M
chr16_+_53434430 0.44 ENST00000262133.11
RB transcriptional corepressor like 2
chr10_+_79068955 0.43 ENST00000334512.10
zinc finger MIZ-type containing 1
chr16_+_70114306 0.43 ENST00000288050.9
ENST00000398122.7
ENST00000568530.5
pyruvate dehydrogenase phosphatase regulatory subunit
chr7_-_94655993 0.43 ENST00000647110.1
ENST00000647048.1
ENST00000643020.1
ENST00000644682.1
ENST00000646119.1
ENST00000646265.1
ENST00000645445.1
ENST00000647334.1
ENST00000645262.1
ENST00000428696.7
ENST00000647096.1
ENST00000642394.1
ENST00000645725.1
ENST00000647351.1
ENST00000646943.1
ENST00000648936.2
ENST00000642707.1
ENST00000645109.1
ENST00000646489.1
ENST00000642933.1
ENST00000643128.1
ENST00000445866.7
ENST00000645101.1
ENST00000644116.1
ENST00000642441.1
ENST00000646879.1
ENST00000647018.1
sarcoglycan epsilon
chr16_+_29806519 0.42 ENST00000322945.11
ENST00000562337.5
ENST00000566906.6
ENST00000563402.1
ENST00000219782.10
MYC associated zinc finger protein
chr11_+_45146631 0.42 ENST00000534751.3
ENST00000683152.1
PR/SET domain 11
chr14_-_39432414 0.42 ENST00000554932.1
ENST00000298097.7
F-box protein 33
chr1_-_153946652 0.41 ENST00000361217.9
DENN domain containing 4B
chrX_+_153072454 0.41 ENST00000421798.5
PNMA family member 6A
chr7_-_150978284 0.41 ENST00000262186.10
potassium voltage-gated channel subfamily H member 2
chr17_+_66964638 0.40 ENST00000262138.4
calcium voltage-gated channel auxiliary subunit gamma 4
chr6_+_156779363 0.40 ENST00000494260.2
ENST00000636748.1
ENST00000636607.1
ENST00000414678.7
ENST00000638000.1
AT-rich interaction domain 1B
chr7_-_94656197 0.40 ENST00000643903.1
ENST00000644122.1
ENST00000447873.6
ENST00000644816.1
ENST00000644375.1
sarcoglycan epsilon
chr3_-_134250744 0.40 ENST00000620660.4
receptor like tyrosine kinase
chr11_+_118359572 0.39 ENST00000252108.8
ENST00000431736.6
ubiquitination factor E4A
chr2_+_177392734 0.39 ENST00000680770.1
ENST00000637633.2
ENST00000679459.1
ENST00000409888.1
ENST00000264167.11
ENST00000642466.2
alkylglycerone phosphate synthase
chr10_-_17617326 0.39 ENST00000326961.6
ENST00000361271.8
3-hydroxyacyl-CoA dehydratase 1
chr7_-_17940468 0.39 ENST00000611725.4
ENST00000409604.1
ENST00000428135.7
sorting nexin 13
chr21_+_41168142 0.39 ENST00000330333.11
beta-secretase 2
chr7_-_94656160 0.39 ENST00000644609.1
ENST00000643272.1
ENST00000646137.1
ENST00000646098.1
ENST00000643193.1
ENST00000437425.7
ENST00000644551.1
ENST00000415788.3
sarcoglycan epsilon
chr10_+_115093404 0.38 ENST00000527407.5
attractin like 1
chr1_-_35557378 0.38 ENST00000325722.8
ENST00000469892.5
KIAA0319 like
chr2_-_219060914 0.38 ENST00000295731.7
Indian hedgehog signaling molecule
chr3_+_14947680 0.37 ENST00000435454.5
ENST00000323373.10
nuclear receptor subfamily 2 group C member 2
chr15_+_40323683 0.37 ENST00000638170.2
InaF motif containing 2
chr9_+_22446808 0.37 ENST00000325870.3
DMRT like family A1
chr3_+_170357647 0.36 ENST00000476188.5
ENST00000259119.9
ENST00000426052.6
SKI like proto-oncogene
chr12_-_31590967 0.36 ENST00000354285.8
DENN domain containing 5B
chr10_-_102120318 0.36 ENST00000673968.1
LIM domain binding 1
chr5_+_176810552 0.36 ENST00000329542.9
unc-5 netrin receptor A
chr18_+_62523002 0.35 ENST00000269499.10
zinc finger CCHC-type containing 2
chr1_-_6485941 0.35 ENST00000676287.1
ENST00000400913.6
pleckstrin homology and RhoGEF domain containing G5
chr12_+_122078740 0.35 ENST00000319080.12
MLX interacting protein
chr14_-_103057509 0.35 ENST00000361246.7
CDC42 binding protein kinase beta
chr22_-_20016807 0.35 ENST00000263207.8
ARVCF delta catenin family member
chr7_+_94656325 0.35 ENST00000482108.1
ENST00000488574.5
ENST00000612748.1
ENST00000613043.1
paternally expressed 10
chr21_+_41167774 0.35 ENST00000328735.10
ENST00000347667.5
beta-secretase 2
chr3_-_38029604 0.35 ENST00000334661.5
phospholipase C delta 1
chr12_-_49828394 0.34 ENST00000335999.7
NCK associated protein 5 like
chr3_+_14947568 0.34 ENST00000413118.5
ENST00000425241.5
nuclear receptor subfamily 2 group C member 2
chr4_+_1793776 0.34 ENST00000352904.6
fibroblast growth factor receptor 3
chr10_+_102644462 0.33 ENST00000643721.2
ENST00000302424.12
tripartite motif containing 8
chr5_+_176810498 0.33 ENST00000509580.2
unc-5 netrin receptor A
chr22_-_31346143 0.33 ENST00000405309.7
ENST00000351933.8
POZ/BTB and AT hook containing zinc finger 1
chr2_-_99489955 0.33 ENST00000393445.7
ENST00000258428.8
REV1 DNA directed polymerase
chr1_-_17011891 0.33 ENST00000341676.9
ENST00000326735.13
ENST00000452699.5
ATPase cation transporting 13A2
chr4_+_173168800 0.33 ENST00000512285.5
ENST00000265000.9
polypeptide N-acetylgalactosaminyltransferase 7
chr5_-_141682192 0.33 ENST00000508305.5
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr14_-_93115270 0.32 ENST00000555553.5
ENST00000555495.5
ENST00000554999.5
inositol-tetrakisphosphate 1-kinase
chr10_+_102420823 0.32 ENST00000369956.8
ENST00000425536.1
F-box and leucine rich repeat protein 15
chr14_+_73950489 0.32 ENST00000554320.1
coenzyme Q6, monooxygenase
chr17_+_29593468 0.32 ENST00000614878.4
ankyrin repeat domain 13B
chr11_-_6655788 0.32 ENST00000299441.5
dachsous cadherin-related 1
chr1_-_53328053 0.32 ENST00000371454.6
ENST00000667377.1
ENST00000306052.12
ENST00000668448.1
LDL receptor related protein 8
chr12_+_2877193 0.32 ENST00000538636.5
ENST00000461997.5
ENST00000618250.4
ENST00000366285.5
ENST00000538700.2
ENST00000489288.7
RAD9-HUS1-RAD1 interacting nuclear orphan 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.2 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210)
0.5 1.5 GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550)
0.5 1.9 GO:0033306 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.4 1.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.4 0.4 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.4 1.1 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.3 0.9 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.2 0.7 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.2 1.0 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273)
0.2 0.6 GO:0043000 Golgi to plasma membrane CFTR protein transport(GO:0043000)
0.2 1.5 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.2 1.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2 3.0 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.2 0.7 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.2 0.5 GO:1905006 negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006)
0.2 0.7 GO:0035854 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.2 0.8 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.2 0.5 GO:1901874 negative regulation of post-translational protein modification(GO:1901874)
0.2 0.5 GO:0033967 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.1 1.1 GO:2000467 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 1.0 GO:0097338 response to clozapine(GO:0097338)
0.1 1.0 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1 0.4 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.1 0.5 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 2.0 GO:0060312 regulation of blood vessel remodeling(GO:0060312)
0.1 0.6 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 1.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.3 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.1 0.4 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 0.6 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 0.3 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.5 GO:0060437 lung growth(GO:0060437)
0.1 1.1 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 0.3 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 0.4 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 6.7 GO:1990090 cellular response to nerve growth factor stimulus(GO:1990090)
0.1 0.3 GO:0060596 mammary placode formation(GO:0060596)
0.1 0.6 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1 1.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.4 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.1 0.4 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 0.2 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.1 0.2 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.2 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.1 0.4 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.7 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 1.0 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.1 0.4 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 0.6 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.2 GO:0043387 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.1 0.2 GO:0060454 positive regulation of gastric acid secretion(GO:0060454)
0.1 0.2 GO:0051230 mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.1 0.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.3 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.1 1.9 GO:0050667 homocysteine metabolic process(GO:0050667)
0.1 0.4 GO:0060179 male mating behavior(GO:0060179)
0.1 0.8 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.3 GO:0018197 peptidyl-aspartic acid modification(GO:0018197)
0.1 0.6 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 0.3 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.1 0.2 GO:0003032 detection of oxygen(GO:0003032)
0.1 0.4 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.1 0.9 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.3 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.7 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 1.0 GO:0036119 response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.4 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.4 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.4 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.4 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.1 GO:0002071 glandular epithelial cell maturation(GO:0002071) positive regulation of type B pancreatic cell development(GO:2000078)
0.0 0.2 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.2 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0 0.7 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.5 GO:0015866 ADP transport(GO:0015866)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.2 GO:0001555 oocyte growth(GO:0001555)
0.0 0.9 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 1.0 GO:2000780 negative regulation of double-strand break repair(GO:2000780)
0.0 0.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.6 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.1 GO:0042335 cuticle development(GO:0042335)
0.0 0.7 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.4 GO:1903012 positive regulation of bone development(GO:1903012)
0.0 0.1 GO:0030806 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821)
0.0 0.1 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.2 GO:0032902 nerve growth factor production(GO:0032902)
0.0 0.9 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.8 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.2 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.1 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 1.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.7 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 1.4 GO:0043486 histone exchange(GO:0043486)
0.0 0.3 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 0.4 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.6 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.9 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.3 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.6 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.3 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.2 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 1.1 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.5 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0031022 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) nuclear migration along microfilament(GO:0031022) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.9 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 4.5 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 1.4 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.6 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.7 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.5 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.3 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.3 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.7 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.2 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.4 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.3 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927) sperm ejaculation(GO:0042713)
0.0 0.4 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.0 0.5 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.5 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.2 GO:0051775 response to redox state(GO:0051775)
0.0 0.1 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.7 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.4 GO:0035411 catenin import into nucleus(GO:0035411)
0.0 0.2 GO:0007144 female meiosis I(GO:0007144)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.1 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.3 GO:0042276 error-prone translesion synthesis(GO:0042276)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.7 GO:0016589 NURF complex(GO:0016589)
0.2 0.7 GO:0072563 endothelial microparticle(GO:0072563)
0.2 1.1 GO:0032302 MutSalpha complex(GO:0032301) MutSbeta complex(GO:0032302)
0.2 1.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 1.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 1.9 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.3 GO:1905103 integral component of lysosomal membrane(GO:1905103)
0.1 0.3 GO:0097224 sperm connecting piece(GO:0097224)
0.1 0.4 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 2.8 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 2.9 GO:0035861 site of double-strand break(GO:0035861)
0.1 0.5 GO:0072487 MSL complex(GO:0072487)
0.1 1.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 1.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.8 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 2.7 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.5 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 3.6 GO:0030175 filopodium(GO:0030175)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 0.1 GO:0071564 npBAF complex(GO:0071564)
0.0 0.7 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.6 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.4 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587) PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0031209 SCAR complex(GO:0031209)
0.0 0.6 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 2.7 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.0 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.8 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.6 1.9 GO:0046577 long-chain-alcohol oxidase activity(GO:0046577)
0.4 1.5 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.3 1.0 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.2 0.7 GO:0080023 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
0.2 1.5 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.2 1.1 GO:0032181 double-strand/single-strand DNA junction binding(GO:0000406) single thymine insertion binding(GO:0032143) dinucleotide repeat insertion binding(GO:0032181)
0.2 2.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 1.9 GO:0019826 oxygen sensor activity(GO:0019826)
0.2 1.1 GO:0034046 poly(G) binding(GO:0034046)
0.2 0.5 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.1 0.7 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.7 GO:0035276 ethanol binding(GO:0035276)
0.1 0.3 GO:0052830 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.1 0.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 1.6 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 1.9 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.4 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.1 0.3 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.1 0.7 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 0.7 GO:0005534 galactose binding(GO:0005534)
0.1 0.9 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.5 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.2 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.1 0.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.3 GO:0038025 reelin receptor activity(GO:0038025)
0.1 0.2 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.3 GO:1903135 cupric ion binding(GO:1903135)
0.1 1.1 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.8 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.0 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.2 GO:0001626 nociceptin receptor activity(GO:0001626)
0.1 0.2 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 0.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 6.9 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.1 0.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 1.0 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.7 GO:0005113 patched binding(GO:0005113)
0.0 0.8 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0055100 adiponectin binding(GO:0055100)
0.0 1.3 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.5 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 4.7 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 1.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 1.1 GO:0071949 FAD binding(GO:0071949)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 1.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.4 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.6 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 1.3 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 1.1 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.1 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 4.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.3 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.7 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.7 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 2.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.6 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 2.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0070546 cysteine-S-conjugate beta-lyase activity(GO:0047804) L-phenylalanine aminotransferase activity(GO:0070546)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.1 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.0 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 3.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 2.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.5 PID ATM PATHWAY ATM pathway
0.0 1.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.7 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.3 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.1 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.7 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.3 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.6 PID FOXO PATHWAY FoxO family signaling
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.6 REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX Genes involved in Signaling by TGF-beta Receptor Complex
0.0 0.6 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 1.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.1 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 2.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.5 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.4 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 1.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.6 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1