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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for MECOM

Z-value: 0.56

Motif logo

Transcription factors associated with MECOM

Gene Symbol Gene ID Gene Info
ENSG00000085276.19 MECOM

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MECOMhg38_v1_chr3_-_169146595_169146675-0.067.8e-01Click!

Activity profile of MECOM motif

Sorted Z-values of MECOM motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MECOM

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr8_-_6563044 1.46 ENST00000338312.10
angiopoietin 2
chr8_-_6563238 1.23 ENST00000629816.3
ENST00000523120.2
angiopoietin 2
chr9_+_79572572 1.19 ENST00000435650.5
ENST00000414465.5
ENST00000376537.8
TLE family member 4, transcriptional corepressor
chr6_-_56542802 0.97 ENST00000524186.1
dystonin
chr14_+_21990357 0.95 ENST00000390444.1
T cell receptor alpha variable 16
chr8_-_6563409 0.82 ENST00000325203.9
angiopoietin 2
chr11_-_33869816 0.72 ENST00000395833.7
LIM domain only 2
chr6_+_29100609 0.69 ENST00000377171.3
olfactory receptor family 2 subfamily J member 1
chr5_+_126360113 0.67 ENST00000513040.5
GRAM domain containing 2B
chr9_+_79571767 0.63 ENST00000376544.7
TLE family member 4, transcriptional corepressor
chr14_+_64214136 0.57 ENST00000557084.1
ENST00000458046.6
spectrin repeat containing nuclear envelope protein 2
chr18_-_12656716 0.53 ENST00000462226.1
ENST00000497844.6
ENST00000309836.9
ENST00000453447.6
spire type actin nucleation factor 1
chr9_+_79571956 0.53 ENST00000376552.8
TLE family member 4, transcriptional corepressor
chr12_-_14885845 0.47 ENST00000539261.6
ENST00000228938.5
matrix Gla protein
chr17_-_68955332 0.43 ENST00000269080.6
ENST00000615593.4
ENST00000586539.6
ENST00000430352.6
ATP binding cassette subfamily A member 8
chr8_-_80080816 0.43 ENST00000520527.5
ENST00000517427.5
ENST00000379097.7
ENST00000448733.3
tumor protein D52
chr12_-_9760893 0.42 ENST00000228434.7
ENST00000536709.1
CD69 molecule
chrX_+_15507302 0.42 ENST00000342014.6
BMX non-receptor tyrosine kinase
chr19_-_35900532 0.41 ENST00000396901.5
ENST00000641389.2
ENST00000585925.7
NFKB inhibitor delta
chr12_+_20695553 0.41 ENST00000545102.1
solute carrier organic anion transporter family member 1C1
chr6_-_154510675 0.40 ENST00000607772.6
CNKSR family member 3
chr12_+_93572664 0.38 ENST00000551556.2
suppressor of cytokine signaling 2
chr10_-_86957582 0.37 ENST00000372027.10
multimerin 2
chr5_+_141223332 0.36 ENST00000239449.7
ENST00000624896.1
ENST00000624396.1
protocadherin beta 14
novel protein
chr4_-_73982019 0.35 ENST00000296029.4
platelet factor 4
chr2_+_241350087 0.34 ENST00000451310.1
septin 2
chr10_+_76318330 0.34 ENST00000496424.2
leucine rich melanocyte differentiation associated
chr1_+_81800368 0.34 ENST00000674489.1
ENST00000674442.1
ENST00000674419.1
ENST00000674407.1
ENST00000674168.1
ENST00000674307.1
ENST00000674209.1
ENST00000370715.5
ENST00000370713.5
ENST00000319517.10
ENST00000627151.2
ENST00000370717.6
adhesion G protein-coupled receptor L2
chr2_+_188974364 0.32 ENST00000304636.9
ENST00000317840.9
collagen type III alpha 1 chain
chr8_-_38150943 0.30 ENST00000276449.9
steroidogenic acute regulatory protein
chr8_-_27258414 0.29 ENST00000523048.5
stathmin 4
chr1_+_160190567 0.28 ENST00000368078.8
calsequestrin 1
chr2_-_144517663 0.27 ENST00000427902.5
ENST00000462355.2
ENST00000470879.5
ENST00000409487.7
ENST00000435831.5
ENST00000630572.2
zinc finger E-box binding homeobox 2
chrX_+_103628692 0.26 ENST00000372626.7
transcription elongation factor A like 1
chr6_-_52995170 0.26 ENST00000370959.1
ENST00000370963.9
glutathione S-transferase alpha 4
chr7_+_44000889 0.24 ENST00000258704.3
speedy/RINGO cell cycle regulator family member E1
chr13_+_32031706 0.24 ENST00000542859.6
FRY microtubule binding protein
chr3_+_119294337 0.23 ENST00000264245.9
Rho GTPase activating protein 31
chr16_-_71724700 0.23 ENST00000568954.5
PH domain and leucine rich repeat protein phosphatase 2
chr13_+_101489940 0.23 ENST00000376162.7
integrin subunit beta like 1
chr7_-_33100886 0.22 ENST00000448915.1
RP9 pre-mRNA splicing factor
chr9_-_13175824 0.22 ENST00000545857.5
multiple PDZ domain crumbs cell polarity complex component
chr12_-_39340963 0.22 ENST00000552961.5
kinesin family member 21A
chr15_-_55270383 0.22 ENST00000396307.6
RAB27A, member RAS oncogene family
chr19_-_14206168 0.21 ENST00000361434.7
ENST00000340736.10
adhesion G protein-coupled receptor L1
chr1_-_97920986 0.21 ENST00000370192.8
dihydropyrimidine dehydrogenase
chr1_-_52055156 0.21 ENST00000371626.9
ENST00000610127.2
thioredoxin domain containing 12
chr3_-_27456743 0.21 ENST00000295736.9
ENST00000428386.5
ENST00000428179.1
solute carrier family 4 member 7
chr15_+_44427793 0.20 ENST00000558966.5
ENST00000559793.5
ENST00000558968.1
CTD small phosphatase like 2
chr6_-_30684744 0.19 ENST00000615892.4
protein phosphatase 1 regulatory subunit 18
chr15_-_55270280 0.19 ENST00000564609.5
RAB27A, member RAS oncogene family
chr22_-_31292445 0.19 ENST00000402249.7
ENST00000215912.10
ENST00000443175.1
ENST00000441972.5
phosphoinositide-3-kinase interacting protein 1
chr9_+_131502789 0.18 ENST00000372228.9
ENST00000341012.13
ENST00000677216.1
ENST00000676640.1
ENST00000441334.5
ENST00000402686.8
ENST00000677029.1
ENST00000676915.1
ENST00000676803.1
ENST00000677293.1
ENST00000678303.1
ENST00000677626.1
ENST00000372220.5
ENST00000683229.1
ENST00000418774.6
ENST00000430619.2
ENST00000448212.5
ENST00000679221.1
ENST00000678785.1
protein O-mannosyltransferase 1
chr1_+_86468902 0.18 ENST00000394711.2
chloride channel accessory 1
chr12_+_18242955 0.18 ENST00000676171.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr11_-_55936400 0.18 ENST00000301532.3
olfactory receptor family 5 subfamily I member 1
chr11_-_18634332 0.17 ENST00000336349.6
SPT2 chromatin protein domain containing 1
chr12_+_12049855 0.17 ENST00000586576.5
ENST00000464885.6
BCL2 like 14
chr1_-_147225309 0.17 ENST00000369272.7
ENST00000254090.9
ENST00000441068.6
flavin containing dimethylaniline monoxygenase 5
chrX_+_103628959 0.17 ENST00000372625.8
ENST00000372624.3
transcription elongation factor A like 1
chr4_+_73853290 0.17 ENST00000226524.4
platelet factor 4 variant 1
chr1_-_147225568 0.16 ENST00000533174.5
ENST00000578284.5
flavin containing dimethylaniline monoxygenase 5
chrX_-_86047527 0.16 ENST00000615443.1
ENST00000357749.7
CHM Rab escort protein
chr19_-_51108365 0.16 ENST00000421832.3
cytosolic thiouridylase subunit 1
chr3_+_109136707 0.16 ENST00000622536.6
chromosome 3 open reading frame 85
chr8_-_92017292 0.16 ENST00000521553.5
RUNX1 partner transcriptional co-repressor 1
chr7_-_76540386 0.16 ENST00000515340.2
ENST00000633306.1
speedy/RINGO cell cycle regulator family member E16
chr19_-_52821631 0.16 ENST00000457749.7
ENST00000391783.6
zinc finger protein 28
chr22_-_28741783 0.16 ENST00000439200.5
ENST00000405598.5
ENST00000398017.3
ENST00000649563.1
ENST00000650281.1
ENST00000425190.7
ENST00000404276.6
ENST00000650233.1
ENST00000348295.7
ENST00000382580.6
checkpoint kinase 2
chr16_+_71845958 0.15 ENST00000427980.7
ENST00000568581.5
ataxin 1 like
IST1 factor associated with ESCRT-III
chr8_-_18084925 0.15 ENST00000637792.1
ENST00000637991.1
ENST00000636537.1
ENST00000636455.1
ENST00000314146.10
ENST00000381733.9
N-acylsphingosine amidohydrolase 1
chrX_+_130339941 0.15 ENST00000218197.9
solute carrier family 25 member 14
chr17_-_58417521 0.15 ENST00000584437.5
ENST00000407977.7
ring finger protein 43
chr17_-_58417547 0.15 ENST00000577716.5
ring finger protein 43
chr6_-_87095059 0.15 ENST00000369582.6
ENST00000610310.3
ENST00000630630.2
ENST00000627148.3
ENST00000625577.1
glycoprotein hormones, alpha polypeptide
chr4_-_87529092 0.15 ENST00000503414.5
SPARC like 1
chr1_-_109613070 0.15 ENST00000351050.8
G protein subunit alpha transducin 2
chr11_+_60378494 0.14 ENST00000534016.5
membrane spanning 4-domains A7
chr2_-_55923775 0.14 ENST00000438672.5
ENST00000355426.8
ENST00000440439.5
ENST00000429909.5
ENST00000424207.5
ENST00000452337.5
ENST00000439193.5
ENST00000421664.1
EGF containing fibulin extracellular matrix protein 1
chrX_-_63755032 0.14 ENST00000624538.2
ENST00000636276.1
ENST00000624843.3
ENST00000671907.1
ENST00000624210.3
ENST00000374870.8
ENST00000635967.1
ENST00000253401.10
ENST00000672194.1
ENST00000637723.2
ENST00000637417.1
ENST00000637520.1
ENST00000374872.4
ENST00000636926.1
Cdc42 guanine nucleotide exchange factor 9
chr1_-_161223408 0.14 ENST00000491350.1
apolipoprotein A2
chr2_+_43838963 0.14 ENST00000272286.4
ATP binding cassette subfamily G member 8
chr7_+_75494980 0.14 ENST00000624640.1
speedy/RINGO cell cycle regulator family member E5
chr11_+_47565430 0.14 ENST00000426530.2
ENST00000534775.1
protein tyrosine phosphatase mitochondrial 1
chr20_+_34241390 0.13 ENST00000374954.4
agouti signaling protein
chr19_-_47232649 0.13 ENST00000449228.5
ENST00000300880.11
ENST00000341983.8
BCL2 binding component 3
chrX_+_30243715 0.13 ENST00000378981.8
ENST00000397550.6
MAGE family member B1
chr17_-_58353069 0.13 ENST00000580947.1
SPT4 homolog, DSIF elongation factor subunit
chr5_+_119629552 0.13 ENST00000613773.4
ENST00000620555.4
ENST00000515256.5
ENST00000509264.1
family with sequence similarity 170 member A
chr12_+_53442555 0.12 ENST00000549135.1
proline rich 13
chr6_-_130222813 0.12 ENST00000437477.6
ENST00000439090.7
sterile alpha motif domain containing 3
chr22_+_29883158 0.12 ENST00000333027.7
ENST00000401950.7
ENST00000445401.5
ENST00000323630.9
ENST00000351488.7
myotubularin related protein 3
chr18_-_24311495 0.12 ENST00000357041.8
oxysterol binding protein like 1A
chr11_+_61222347 0.12 ENST00000378149.9
pepsinogen A4
chr3_-_194672175 0.12 ENST00000265245.10
large 60S subunit nuclear export GTPase 1
chr14_+_24114627 0.12 ENST00000559115.5
ENST00000558215.5
ENST00000557810.5
ENST00000561375.5
ENST00000446197.8
ENST00000559796.5
ENST00000560713.5
ENST00000560901.5
ENST00000559382.5
ENST00000561001.5
DDB1 and CUL4 associated factor 11
chr7_-_76541459 0.12 ENST00000632547.1
speedy/RINGO cell cycle regulator family member E16
chr17_-_39152571 0.12 ENST00000415163.5
ENST00000441877.5
ENST00000444911.6
plexin domain containing 1
chr3_+_4303304 0.12 ENST00000358065.4
SET domain and mariner transposase fusion gene
chr7_+_44200960 0.11 ENST00000496112.5
ENST00000678359.1
ENST00000223369.3
ENST00000677090.1
YKT6 v-SNARE homolog
chr19_+_22052507 0.11 ENST00000600162.1
zinc finger protein 257
chr17_-_42194459 0.11 ENST00000593209.5
ENST00000588352.5
ENST00000587427.6
ENST00000414034.7
ENST00000590249.5
ENST00000428494.6
GH3 domain containing
chr14_+_24115299 0.11 ENST00000559354.5
ENST00000560459.5
ENST00000559593.5
ENST00000396941.8
ENST00000396936.5
DDB1 and CUL4 associated factor 11
chr12_+_15546344 0.10 ENST00000674388.1
ENST00000542557.5
ENST00000445537.6
ENST00000544244.5
ENST00000442921.7
protein tyrosine phosphatase receptor type O
chr14_+_22543179 0.10 ENST00000390534.1
T cell receptor alpha joining 3
chr15_+_70892809 0.10 ENST00000260382.10
ENST00000560755.5
leucine rich repeat containing 49
chr12_-_12562344 0.10 ENST00000228862.3
dual specificity phosphatase 16
chr3_-_45842066 0.10 ENST00000445698.1
ENST00000296135.11
leucine zipper transcription factor like 1
chr5_+_102865805 0.10 ENST00000346918.7
peptidylglycine alpha-amidating monooxygenase
chrX_-_10620534 0.10 ENST00000317552.9
midline 1
chr10_-_20897288 0.10 ENST00000377122.9
nebulette
chr12_+_54854505 0.10 ENST00000308796.11
ENST00000619042.1
mucin like 1
chr19_+_49527988 0.10 ENST00000270645.8
reticulocalbin 3
chr6_-_32816910 0.10 ENST00000447394.1
ENST00000438763.7
major histocompatibility complex, class II, DO beta
chrX_+_102247167 0.09 ENST00000625106.4
nuclear RNA export factor 2
chr16_+_2817230 0.09 ENST00000005995.8
ENST00000574813.5
serine protease 21
chr10_+_113129285 0.09 ENST00000637574.1
transcription factor 7 like 2
chr1_+_50103903 0.09 ENST00000371827.5
ELAV like RNA binding protein 4
chrX_-_10620419 0.09 ENST00000380782.6
midline 1
chr11_-_82846128 0.09 ENST00000679809.1
ENST00000680186.1
ENST00000681592.1
prolylcarboxypeptidase
chr8_-_113436883 0.09 ENST00000455883.2
ENST00000297405.10
CUB and Sushi multiple domains 3
chr5_+_141408032 0.09 ENST00000520790.1
protocadherin gamma subfamily B, 6
chr15_-_40108861 0.08 ENST00000354670.9
ENST00000559701.5
ENST00000557870.1
ENST00000558774.5
Bcl2 modifying factor
chrX_-_102439932 0.08 ENST00000602195.5
nuclear RNA export factor 2B
chrX_+_102307022 0.08 ENST00000604790.2
nuclear RNA export factor 2
chr5_-_159330481 0.08 ENST00000231228.3
interleukin 12B
chr5_+_141408000 0.08 ENST00000616430.1
protocadherin gamma subfamily B, 6
chr4_-_75673112 0.08 ENST00000395719.7
ENST00000677489.1
G3BP stress granule assembly factor 2
chr3_-_193554952 0.08 ENST00000392443.7
ATPase 13A4
chr18_-_27143024 0.08 ENST00000581714.5
carbohydrate sulfotransferase 9
chr6_+_69232406 0.08 ENST00000238918.12
adhesion G protein-coupled receptor B3
chr5_+_57175803 0.08 ENST00000511209.5
GC-rich promoter binding protein 1
chr11_+_60378475 0.08 ENST00000358246.5
membrane spanning 4-domains A7
chrX_+_87517784 0.08 ENST00000373119.9
ENST00000373114.4
kelch like family member 4
chr4_-_75673139 0.07 ENST00000677566.1
ENST00000503660.5
ENST00000677060.1
ENST00000678552.1
G3BP stress granule assembly factor 2
chr5_-_83720813 0.07 ENST00000515590.1
ENST00000274341.9
hyaluronan and proteoglycan link protein 1
chr18_+_58362467 0.07 ENST00000675101.1
NEDD4 like E3 ubiquitin protein ligase
chr22_+_35717872 0.07 ENST00000249044.2
apolipoprotein L5
chr17_-_3104422 0.07 ENST00000641064.1
ENST00000641833.1
olfactory receptor family 1 subfamily D member 2
chr14_+_66486356 0.07 ENST00000636229.1
coiled-coil domain containing 196
chr2_-_236507428 0.07 ENST00000409907.8
IQ motif containing with AAA domain 1
chrX_-_40096190 0.06 ENST00000679513.1
BCL6 corepressor
chr11_+_17295322 0.06 ENST00000458064.6
ENST00000622082.4
nucleobindin 2
chrX_+_136648214 0.06 ENST00000370628.2
CD40 ligand
chr8_+_133191029 0.06 ENST00000250160.11
cellular communication network factor 4
chr16_+_10743786 0.06 ENST00000574334.5
ENST00000283027.10
ENST00000433392.6
nucleotide binding protein 1
chr12_+_20695323 0.06 ENST00000266509.7
solute carrier organic anion transporter family member 1C1
chr2_-_74648307 0.06 ENST00000421985.2
ENST00000536235.5
meiosis 1 associated protein
chr9_-_27005659 0.06 ENST00000380055.6
leucine rich repeat containing 19
chr19_-_14090695 0.06 ENST00000533683.7
sterile alpha motif domain containing 1
chr3_-_193554885 0.06 ENST00000342695.9
ATPase 13A4
chrX_-_19965142 0.06 ENST00000340625.3
BCLAF1 and THRAP3 family member 3
chr15_-_29968864 0.06 ENST00000356107.11
tight junction protein 1
chr1_+_154983318 0.06 ENST00000292180.8
ENST00000368433.5
ENST00000315144.14
ENST00000368432.5
ENST00000368431.7
flavin adenine dinucleotide synthetase 1
chr4_-_75673360 0.06 ENST00000676584.1
ENST00000678329.1
ENST00000677889.1
ENST00000357854.7
ENST00000359707.9
ENST00000676974.1
ENST00000678273.1
ENST00000677201.1
ENST00000678244.1
ENST00000677125.1
ENST00000677162.1
G3BP stress granule assembly factor 2
chrX_+_136648138 0.06 ENST00000370629.7
CD40 ligand
chr4_+_70334963 0.06 ENST00000273936.6
calcium binding protein, spermatid associated 1
chr13_+_108218366 0.06 ENST00000375898.4
abhydrolase domain containing 13
chr1_-_97921042 0.06 ENST00000306031.5
dihydropyrimidine dehydrogenase
chr6_-_41201128 0.05 ENST00000483722.2
triggering receptor expressed on myeloid cells like 2
chr7_-_8262533 0.05 ENST00000447326.5
ENST00000406470.6
ENST00000407906.5
islet cell autoantigen 1
chr10_+_104275126 0.05 ENST00000369707.2
glutathione S-transferase omega 2
chr5_-_65624288 0.05 ENST00000381018.7
ENST00000274327.11
ENST00000231524.14
tripartite motif containing 23
chr2_-_236507515 0.05 ENST00000309507.9
IQ motif containing with AAA domain 1
chr12_-_8662703 0.05 ENST00000535336.5
microfibril associated protein 5
chr14_-_24114913 0.05 ENST00000561028.6
ENST00000558280.1
neural retina leucine zipper
chrY_+_25622162 0.05 ENST00000361963.3
ENST00000306609.4
chromodomain Y-linked 1
chr11_+_60378524 0.05 ENST00000530614.5
ENST00000530027.5
ENST00000300184.8
ENST00000530234.2
ENST00000528215.1
ENST00000531787.5
membrane spanning 4-domains A7
membrane spanning 4-domains A14
chr2_-_231125032 0.05 ENST00000258400.4
5-hydroxytryptamine receptor 2B
chr8_-_39838250 0.05 ENST00000622267.1
ADAM metallopeptidase domain 2
chr15_+_65869974 0.05 ENST00000567671.1
RAB11A, member RAS oncogene family
chr1_+_103749898 0.05 ENST00000622339.5
amylase alpha 1C
chr5_+_75512058 0.05 ENST00000514296.5
DNA polymerase kappa
chr7_-_120858066 0.04 ENST00000222747.8
tetraspanin 12
chr19_-_45863130 0.04 ENST00000599460.5
ENST00000245934.12
ENST00000598059.5
symplekin
chr10_-_29634964 0.04 ENST00000375398.6
ENST00000355867.8
supervillin
chr13_-_60013178 0.04 ENST00000498416.2
ENST00000465066.5
diaphanous related formin 3
chr10_-_32935511 0.04 ENST00000423113.5
integrin subunit beta 1
chr17_+_55267584 0.04 ENST00000575345.5
HLF transcription factor, PAR bZIP family member
chr20_+_15196834 0.04 ENST00000402914.5
mono-ADP ribosylhydrolase 2
chr11_-_5227063 0.04 ENST00000335295.4
ENST00000485743.1
ENST00000647020.1
hemoglobin subunit beta
chr10_+_29289061 0.04 ENST00000375500.8
ENST00000649382.2
lysozyme like 1
chr3_-_193554799 0.04 ENST00000295548.3
ATPase 13A4
chr5_-_147782681 0.04 ENST00000616793.5
ENST00000333010.6
ENST00000265272.9
janus kinase and microtubule interacting protein 2
chr9_-_127578989 0.03 ENST00000373314.7
niban apoptosis regulator 2
chr20_+_34194569 0.03 ENST00000568305.5
agouti signaling protein
chr8_-_39838201 0.03 ENST00000347580.8
ENST00000379853.6
ENST00000265708.9
ENST00000521880.5
ADAM metallopeptidase domain 2
chr6_+_152697888 0.03 ENST00000367245.5
ENST00000529453.1
MYC target 1
chr3_-_139476508 0.03 ENST00000232217.6
retinol binding protein 2
chr1_+_209686173 0.03 ENST00000615289.4
ENST00000367028.6
ENST00000261465.5
hydroxysteroid 11-beta dehydrogenase 1
chr18_+_21363593 0.03 ENST00000580732.6
GREB1 like retinoic acid receptor coactivator
chr7_-_108130349 0.03 ENST00000205386.8
ENST00000418464.1
ENST00000388781.8
laminin subunit beta 4
chr5_-_39364484 0.03 ENST00000263408.5
complement C9
chr19_+_15010720 0.03 ENST00000292574.4
coiled-coil domain containing 105
chr3_+_122055355 0.03 ENST00000330540.7
ENST00000469710.5
ENST00000493101.5
CD86 molecule
chr17_-_45060988 0.03 ENST00000342350.9
dephospho-CoA kinase domain containing
chr9_+_116153783 0.03 ENST00000328252.4
pappalysin 1
chr9_-_92482350 0.03 ENST00000375543.2
asporin
chr10_-_67696115 0.02 ENST00000433211.7
catenin alpha 3
chr11_+_61241175 0.02 ENST00000312403.10
pepsinogen A5

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.1 0.3 GO:0018963 phthalate metabolic process(GO:0018963) positive regulation of bile acid biosynthetic process(GO:0070859) cellular response to luteinizing hormone stimulus(GO:0071373) positive regulation of bile acid metabolic process(GO:1904253)
0.1 0.3 GO:0019483 uracil catabolic process(GO:0006212) beta-alanine biosynthetic process(GO:0019483)
0.1 0.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.6 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.4 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.2 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.4 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.1 0.5 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.1 1.0 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.2 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.3 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347) negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.0 0.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.4 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.2 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.1 GO:0060621 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.0 0.1 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.0 0.3 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.2 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.0 0.1 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0 2.4 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.1 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.0 0.2 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.2 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.1 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.4 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.7 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.4 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.1 GO:0018032 protein amidation(GO:0018032)
0.0 0.3 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.1 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727) flavin adenine dinucleotide metabolic process(GO:0072387)
0.0 0.2 GO:0009838 abscission(GO:0009838)
0.0 0.1 GO:0099558 maintenance of synapse structure(GO:0099558)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.0 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.0 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.1 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.3 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.1 GO:0002254 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0031673 H zone(GO:0031673)
0.1 0.3 GO:0097679 other organism cytoplasm(GO:0097679)
0.0 0.3 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.6 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.3 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0032044 DSIF complex(GO:0032044)
0.0 0.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.2 GO:0031906 late endosome lumen(GO:0031906)
0.0 0.0 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.2 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.1 0.5 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.2 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 0.2 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.4 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 3.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.4 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0031781 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.4 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 2.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.7 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.3 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.0 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 4.0 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 2.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.5 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 2.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport