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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for MEF2B

Z-value: 0.60

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Transcription factors associated with MEF2B

Gene Symbol Gene ID Gene Info
MEF2B
ENSG00000213999.17 MEF2B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MEF2Bhg38_v1_chr19_-_19192122_19192165-0.572.8e-03Click!

Activity profile of MEF2B motif

Sorted Z-values of MEF2B motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MEF2B

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_+_41360759 3.72 ENST00000508501.5
ENST00000512946.5
ENST00000313860.11
ENST00000512632.5
ENST00000512820.5
LIMCH1
LIM and calponin homology domains 1
chr2_-_156342348 3.22 ENST00000409572.5
NR4A2
nuclear receptor subfamily 4 group A member 2
chr5_-_111756245 2.85 ENST00000447165.6
NREP
neuronal regeneration related protein
chr12_+_52051402 2.77 ENST00000243050.5
ENST00000550763.1
ENST00000394825.6
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
NR4A1
nuclear receptor subfamily 4 group A member 1
chr2_+_238138661 2.63 ENST00000409223.2
KLHL30
kelch like family member 30
chr1_+_84164962 2.11 ENST00000614872.4
ENST00000394839.6
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr3_+_8501846 2.00 ENST00000454244.4
LMCD1
LIM and cysteine rich domains 1
chr7_+_30911845 1.95 ENST00000652696.1
ENST00000311813.11
AQP1
aquaporin 1 (Colton blood group)
chr18_+_44680093 1.94 ENST00000426838.8
ENST00000677068.1
SETBP1
SET binding protein 1
chr5_-_88883701 1.86 ENST00000636998.1
MEF2C
myocyte enhancer factor 2C
chr3_+_8501807 1.58 ENST00000426878.2
ENST00000397386.7
ENST00000415597.5
ENST00000157600.8
LMCD1
LIM and cysteine rich domains 1
chr12_+_43836043 1.43 ENST00000266534.8
ENST00000551577.5
TMEM117
transmembrane protein 117
chr1_+_89633086 1.32 ENST00000370454.9
LRRC8C
leucine rich repeat containing 8 VRAC subunit C
chr12_+_78863962 1.26 ENST00000393240.7
SYT1
synaptotagmin 1
chr1_-_145910031 1.25 ENST00000369304.8
ITGA10
integrin subunit alpha 10
chr1_-_145910066 1.22 ENST00000539363.2
ITGA10
integrin subunit alpha 10
chr11_+_7576975 1.19 ENST00000684215.1
ENST00000650027.1
PPFIBP2
PPFIA binding protein 2
chr7_-_15686671 0.98 ENST00000262041.6
MEOX2
mesenchyme homeobox 2
chr1_-_58784035 0.84 ENST00000371222.4
JUN
Jun proto-oncogene, AP-1 transcription factor subunit
chr22_-_50578417 0.82 ENST00000312108.12
ENST00000395650.6
CPT1B
carnitine palmitoyltransferase 1B
chr4_-_25863537 0.80 ENST00000502949.5
ENST00000264868.9
ENST00000513691.1
ENST00000514872.1
SEL1L3
SEL1L family member 3
chr7_-_105691637 0.71 ENST00000472195.1
ATXN7L1
ataxin 7 like 1
chr9_-_95509241 0.68 ENST00000331920.11
PTCH1
patched 1
chr13_-_44437214 0.68 ENST00000622051.1
TSC22D1
TSC22 domain family member 1
chr20_+_11917859 0.67 ENST00000618296.4
ENST00000378226.7
BTBD3
BTB domain containing 3
chr14_-_21537206 0.65 ENST00000614342.1
SALL2
spalt like transcription factor 2
chr20_+_58907981 0.65 ENST00000656419.1
GNAS
GNAS complex locus
chr3_+_179653129 0.64 ENST00000680008.1
USP13
ubiquitin specific peptidase 13
chr11_+_9575496 0.64 ENST00000681684.1
WEE1
WEE1 G2 checkpoint kinase
chr2_+_33436304 0.64 ENST00000402538.7
RASGRP3
RAS guanyl releasing protein 3
chr7_+_76302665 0.61 ENST00000248553.7
ENST00000674638.1
ENST00000674547.1
ENST00000675226.1
ENST00000675538.1
ENST00000676231.1
ENST00000675134.1
ENST00000675906.1
ENST00000674650.1
HSPB1
heat shock protein family B (small) member 1
chr15_-_52678560 0.59 ENST00000562351.2
ENST00000261844.11
ENST00000399202.8
ENST00000562135.5
FAM214A
family with sequence similarity 214 member A
chr10_-_3785179 0.59 ENST00000469435.1
KLF6
Kruppel like factor 6
chr8_+_2045037 0.58 ENST00000262113.9
MYOM2
myomesin 2
chr1_+_84164684 0.57 ENST00000370680.5
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr9_+_121286115 0.55 ENST00000477104.2
ENST00000394353.7
GSN
gelsolin
chr11_+_92224801 0.55 ENST00000525166.6
FAT3
FAT atypical cadherin 3
chr6_-_69699124 0.54 ENST00000651675.1
LMBRD1
LMBR1 domain containing 1
chr15_+_84817346 0.53 ENST00000258888.6
ALPK3
alpha kinase 3
chr8_+_2045058 0.52 ENST00000523438.1
MYOM2
myomesin 2
chr12_+_25052512 0.46 ENST00000557489.5
ENST00000354454.7
ENST00000536173.5
IRAG2
inositol 1,4,5-triphosphate receptor associated 2
chr16_-_31428325 0.46 ENST00000287490.5
COX6A2
cytochrome c oxidase subunit 6A2
chr20_+_10218808 0.45 ENST00000254976.7
ENST00000304886.6
SNAP25
synaptosome associated protein 25
chr16_+_31214088 0.44 ENST00000613872.1
TRIM72
tripartite motif containing 72
chr5_-_42811884 0.44 ENST00000514985.6
ENST00000511224.5
ENST00000507920.5
ENST00000510965.1
SELENOP
selenoprotein P
chr16_+_31214111 0.41 ENST00000322122.8
TRIM72
tripartite motif containing 72
chr3_+_159852933 0.40 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr6_+_25726767 0.39 ENST00000274764.5
H2BC1
H2B clustered histone 1
chr5_+_54455661 0.39 ENST00000302005.3
HSPB3
heat shock protein family B (small) member 3
chr16_+_11965193 0.38 ENST00000053243.6
ENST00000396495.3
TNFRSF17
TNF receptor superfamily member 17
chrX_-_21758097 0.36 ENST00000379494.4
SMPX
small muscle protein X-linked
chr3_+_138348570 0.36 ENST00000423968.7
MRAS
muscle RAS oncogene homolog
chr17_+_44170695 0.35 ENST00000293414.6
ASB16
ankyrin repeat and SOCS box containing 16
chr7_-_78489900 0.34 ENST00000636039.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr3_+_179653032 0.34 ENST00000680587.1
ENST00000681064.1
ENST00000263966.8
ENST00000681358.1
ENST00000679749.1
USP13
ubiquitin specific peptidase 13
chr12_+_15546344 0.32 ENST00000674388.1
ENST00000542557.5
ENST00000445537.6
ENST00000544244.5
ENST00000442921.7
PTPRO
protein tyrosine phosphatase receptor type O
chr21_-_33643926 0.31 ENST00000438788.1
CRYZL1
crystallin zeta like 1
chr9_-_72365198 0.30 ENST00000376962.10
ENST00000376960.8
ZFAND5
zinc finger AN1-type containing 5
chr14_-_93955577 0.29 ENST00000555507.5
ASB2
ankyrin repeat and SOCS box containing 2
chr17_-_36090133 0.29 ENST00000613922.2
CCL3
C-C motif chemokine ligand 3
chr7_+_87152531 0.27 ENST00000432366.6
ENST00000423590.6
ENST00000394703.9
DMTF1
cyclin D binding myb like transcription factor 1
chr7_+_18496269 0.27 ENST00000432645.6
HDAC9
histone deacetylase 9
chr7_-_37448845 0.27 ENST00000310758.9
ELMO1
engulfment and cell motility 1
chr3_+_138348592 0.26 ENST00000621127.4
ENST00000494949.5
MRAS
muscle RAS oncogene homolog
chr1_-_114780624 0.26 ENST00000060969.6
ENST00000369528.9
SIKE1
suppressor of IKBKE 1
chr14_-_20436161 0.24 ENST00000636854.3
KLHL33
kelch like family member 33
chr15_+_40239420 0.23 ENST00000560346.5
PAK6
p21 (RAC1) activated kinase 6
chr10_-_3785197 0.23 ENST00000497571.6
KLF6
Kruppel like factor 6
chr12_+_53461015 0.23 ENST00000553064.6
ENST00000547859.2
PCBP2
poly(rC) binding protein 2
chr10_-_3785225 0.23 ENST00000542957.1
KLF6
Kruppel like factor 6
chr1_+_167094049 0.23 ENST00000361200.7
STYXL2
serine/threonine/tyrosine interacting like 2
chr2_+_219253243 0.23 ENST00000490341.3
TUBA4B
tubulin alpha 4b
chr14_+_55580196 0.21 ENST00000395314.8
ENST00000554567.1
ENST00000555498.5
ENST00000438792.6
ENST00000395308.5
KTN1
kinectin 1
chr15_+_40239042 0.20 ENST00000558055.5
ENST00000455577.6
PAK6
p21 (RAC1) activated kinase 6
chr1_+_22451843 0.19 ENST00000375647.5
ENST00000404138.5
ENST00000374651.8
ENST00000400239.6
ZBTB40
zinc finger and BTB domain containing 40
chr18_+_3252267 0.19 ENST00000536605.1
ENST00000580887.5
MYL12A
myosin light chain 12A
chr19_-_49423441 0.19 ENST00000270631.2
PTH2
parathyroid hormone 2
chrX_+_71301742 0.19 ENST00000373829.8
ENST00000538820.1
ITGB1BP2
integrin subunit beta 1 binding protein 2
chr12_-_102481744 0.18 ENST00000644491.1
IGF1
insulin like growth factor 1
chr1_+_26021768 0.18 ENST00000374280.4
EXTL1
exostosin like glycosyltransferase 1
chr12_+_25052634 0.18 ENST00000548766.5
IRAG2
inositol 1,4,5-triphosphate receptor associated 2
chr19_+_16496383 0.17 ENST00000594035.5
ENST00000221671.8
ENST00000599550.1
ENST00000594813.1
C19orf44
chromosome 19 open reading frame 44
chr6_+_44227025 0.17 ENST00000371708.1
SLC29A1
solute carrier family 29 member 1 (Augustine blood group)
chr20_-_63951122 0.17 ENST00000369908.9
UCKL1
uridine-cytidine kinase 1 like 1
chr19_+_56202273 0.17 ENST00000534327.6
ZSCAN5C
zinc finger and SCAN domain containing 5C
chr12_+_119178920 0.15 ENST00000281938.7
HSPB8
heat shock protein family B (small) member 8
chr4_-_142846275 0.14 ENST00000513000.5
ENST00000509777.5
ENST00000503927.5
INPP4B
inositol polyphosphate-4-phosphatase type II B
chr15_+_39934103 0.14 ENST00000263791.10
ENST00000559624.5
ENST00000560648.1
EIF2AK4
eukaryotic translation initiation factor 2 alpha kinase 4
chr11_-_47378494 0.13 ENST00000533030.1
SPI1
Spi-1 proto-oncogene
chr5_-_16508812 0.13 ENST00000683414.1
RETREG1
reticulophagy regulator 1
chr4_-_142305935 0.13 ENST00000511838.5
INPP4B
inositol polyphosphate-4-phosphatase type II B
chr6_+_151807319 0.13 ENST00000443427.5
ESR1
estrogen receptor 1
chr12_-_262828 0.13 ENST00000343164.9
ENST00000436453.1
ENST00000445055.6
ENST00000546319.5
SLC6A13
solute carrier family 6 member 13
chr6_-_33192454 0.12 ENST00000395194.1
ENST00000341947.7
ENST00000374708.8
COL11A2
collagen type XI alpha 2 chain
chr8_+_141417902 0.12 ENST00000681443.1
PTP4A3
protein tyrosine phosphatase 4A3
chr12_+_119178953 0.11 ENST00000674542.1
HSPB8
heat shock protein family B (small) member 8
chr15_+_68054308 0.11 ENST00000249636.11
PIAS1
protein inhibitor of activated STAT 1
chr4_+_44678412 0.11 ENST00000281543.6
GUF1
GTP binding elongation factor GUF1
chr1_-_18902520 0.11 ENST00000538839.5
ENST00000290597.9
ENST00000375341.8
ALDH4A1
aldehyde dehydrogenase 4 family member A1
chr19_-_39833615 0.10 ENST00000593685.5
ENST00000600611.5
DYRK1B
dual specificity tyrosine phosphorylation regulated kinase 1B
chr18_+_3252208 0.10 ENST00000578562.6
MYL12A
myosin light chain 12A
chr17_-_36196748 0.10 ENST00000619989.1
CCL3L1
C-C motif chemokine ligand 3 like 1
chr1_-_156490599 0.09 ENST00000360595.7
MEF2D
myocyte enhancer factor 2D
chr15_+_42359454 0.09 ENST00000349748.8
ENST00000318023.11
ENST00000397163.8
CAPN3
calpain 3
chr4_+_119135825 0.08 ENST00000307128.6
MYOZ2
myozenin 2
chr5_-_16508951 0.08 ENST00000682628.1
RETREG1
reticulophagy regulator 1
chr5_-_16508858 0.07 ENST00000684456.1
RETREG1
reticulophagy regulator 1
chr3_+_46883337 0.07 ENST00000313049.9
PTH1R
parathyroid hormone 1 receptor
chr11_-_47378391 0.07 ENST00000227163.8
SPI1
Spi-1 proto-oncogene
chr3_+_127915226 0.06 ENST00000405109.5
KBTBD12
kelch repeat and BTB domain containing 12
chr17_-_9791586 0.05 ENST00000571134.2
DHRS7C
dehydrogenase/reductase 7C
chr1_+_74235377 0.05 ENST00000326637.8
TNNI3K
TNNI3 interacting kinase
chr4_-_142305826 0.04 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase type II B
chr5_-_67196791 0.04 ENST00000256447.5
CD180
CD180 molecule
chr10_-_95069489 0.04 ENST00000371270.6
ENST00000535898.5
ENST00000623108.3
CYP2C8
cytochrome P450 family 2 subfamily C member 8
chr8_+_106270161 0.04 ENST00000517566.7
ENST00000531443.6
OXR1
oxidation resistance 1
chr11_-_47378527 0.02 ENST00000378538.8
SPI1
Spi-1 proto-oncogene
chr8_-_7452365 0.02 ENST00000458665.5
ENST00000528168.3
SPAG11B
sperm associated antigen 11B
chr19_-_15898057 0.02 ENST00000011989.11
ENST00000221700.11
CYP4F2
cytochrome P450 family 4 subfamily F member 2
chr7_+_143316105 0.02 ENST00000343257.7
ENST00000650516.1
CLCN1
chloride voltage-gated channel 1
chr8_-_94553444 0.02 ENST00000297591.10
ENST00000421249.2
VIRMA
vir like m6A methyltransferase associated
chr9_+_113594118 0.02 ENST00000620489.1
RGS3
regulator of G protein signaling 3
chr11_+_1839452 0.01 ENST00000381906.5
TNNI2
troponin I2, fast skeletal type
chr11_-_89063631 0.01 ENST00000455756.6
GRM5
glutamate metabotropic receptor 5
chr10_-_95441015 0.01 ENST00000371241.5
ENST00000354106.7
ENST00000371239.5
ENST00000361941.7
ENST00000277982.9
ENST00000371245.7
SORBS1
sorbin and SH3 domain containing 1
chr11_+_75399508 0.00 ENST00000531188.6
ENST00000530164.5
ENST00000422465.6
ENST00000278572.10
ENST00000534440.5
ENST00000527446.5
ENST00000526608.5
ENST00000527273.5
ENST00000524851.5
RPS3
ribosomal protein S3
chr1_-_150720842 0.00 ENST00000442853.5
ENST00000368995.8
ENST00000322343.11
ENST00000361824.7
HORMAD1
HORMA domain containing 1
chr1_-_146021724 0.00 ENST00000475797.1
ENST00000497365.5
ENST00000336751.11
ENST00000634927.1
ENST00000421822.2
HJV
hemojuvelin BMP co-receptor
chr13_+_38687068 0.00 ENST00000280481.9
FREM2
FRAS1 related extracellular matrix 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.7 2.0 GO:0030185 nitric oxide transport(GO:0030185) cerebrospinal fluid secretion(GO:0033326) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.4 1.3 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.4 2.8 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.4 2.7 GO:0097338 response to clozapine(GO:0097338)
0.3 0.8 GO:0051365 leading edge cell differentiation(GO:0035026) cellular response to potassium ion starvation(GO:0051365)
0.2 1.0 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.2 1.9 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.2 1.0 GO:0001757 somite specification(GO:0001757)
0.2 0.7 GO:0010157 response to chlorate(GO:0010157)
0.2 0.5 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.1 0.6 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.1 3.8 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.6 GO:0044858 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1 0.5 GO:0038016 insulin receptor internalization(GO:0038016)
0.1 0.3 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.9 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.5 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.3 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.2 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.4 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.6 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.8 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 0.3 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.1 GO:0044828 positive regulation of translational initiation in response to stress(GO:0032058) negative regulation by host of viral genome replication(GO:0044828)
0.0 0.2 GO:0061709 reticulophagy(GO:0061709)
0.0 0.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.2 GO:0044211 CTP salvage(GO:0044211)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 2.5 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.1 GO:0060068 vagina development(GO:0060068)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.5 2.0 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.3 1.3 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 2.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.8 GO:0035976 AP1 complex(GO:0035976)
0.1 0.7 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.4 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0005592 collagen type XI trimer(GO:0005592)
0.0 0.6 GO:0030478 actin cap(GO:0030478)
0.0 0.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.4 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 1.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.4 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.3 2.5 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2 1.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 2.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 0.6 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.1 1.0 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.8 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.1 0.7 GO:0005119 smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108)
0.1 2.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.9 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.3 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.1 0.5 GO:0015235 cobalamin transporter activity(GO:0015235)
0.1 0.3 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.2 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.8 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.6 GO:0045159 myosin II binding(GO:0045159)
0.0 0.4 GO:0008430 selenium binding(GO:0008430)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 2.8 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.6 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 1.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.5 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 2.7 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 2.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.8 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 2.2 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.6 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.1 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.3 PID FOXO PATHWAY FoxO family signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.7 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 2.7 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 2.8 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.6 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.8 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 3.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 1.9 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.8 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 2.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.6 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 0.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.3 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)