ISMARA results: MEF2C

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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for MEF2C

Z-value: 0.63

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Transcription factors associated with MEF2C

Gene Symbol	Gene ID	Gene Info
MEF2C Ensembl NCBI GeneCards UniProt	ENSG00000081189.16	MEF2C

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
MEF2C	hg38_v1_chr5_-_88877967_88877999	0.54	5.6e-03	Click!

Activity profile of MEF2C motif

Sorted Z-values of MEF2C motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MEF2C

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View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr4_-_185775890 Show fit	4.69	ENST00000437304.6	SORBS2 Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 2
chr5_-_111756245 Show fit	4.38	ENST00000447165.6	NREP Ensembl NCBI GeneCards UniProt Show fit	neuronal regeneration related protein
chr4_+_41360759 Show fit	3.77	ENST00000508501.5 ENST00000512946.5 ENST00000313860.11 ENST00000512632.5 ENST00000512820.5	LIMCH1 Ensembl NCBI GeneCards UniProt Show fit	LIM and calponin homology domains 1
chr3_+_8501846 Show fit	3.66	ENST00000454244.4	LMCD1 Ensembl NCBI GeneCards UniProt Show fit	LIM and cysteine rich domains 1
chr3_+_8501807 Show fit	2.82	ENST00000426878.2 ENST00000397386.7 ENST00000415597.5 ENST00000157600.8	LMCD1 Ensembl NCBI GeneCards UniProt Show fit	LIM and cysteine rich domains 1
chr15_-_70702273 Show fit	2.64	ENST00000558758.5 ENST00000379983.6 ENST00000560441.5	UACA Ensembl NCBI GeneCards UniProt Show fit	uveal autoantigen with coiled-coil domains and ankyrin repeats
chr6_-_75493629 Show fit	2.60	ENST00000393004.6	FILIP1 Ensembl NCBI GeneCards UniProt Show fit	filamin A interacting protein 1
chr2_+_238138661 Show fit	2.39	ENST00000409223.2	KLHL30 Ensembl NCBI GeneCards UniProt Show fit	kelch like family member 30
chr4_-_185775271 Show fit	2.31	ENST00000430503.5 ENST00000319454.10 ENST00000450341.5	SORBS2 Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 2
chr4_+_41612892 Show fit	2.31	ENST00000509454.5 ENST00000396595.7 ENST00000381753.8	LIMCH1 Ensembl NCBI GeneCards UniProt Show fit	LIM and calponin homology domains 1
chr2_-_156342348 Show fit	2.23	ENST00000409572.5	NR4A2 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 4 group A member 2
chr7_+_30911845 Show fit	2.18	ENST00000652696.1 ENST00000311813.11	AQP1 Ensembl NCBI GeneCards UniProt Show fit	aquaporin 1 (Colton blood group)
chr4_+_41612702 Show fit	2.17	ENST00000509277.5	LIMCH1 Ensembl NCBI GeneCards UniProt Show fit	LIM and calponin homology domains 1
chr3_+_194136138 Show fit	2.14	ENST00000232424.4	HES1 Ensembl NCBI GeneCards UniProt Show fit	hes family bHLH transcription factor 1
chr15_-_68820861 Show fit	1.76	ENST00000560303.1 ENST00000465139.6	ANP32A Ensembl NCBI GeneCards UniProt Show fit	acidic nuclear phosphoprotein 32 family member A
chr9_+_124291935 Show fit	1.62	ENST00000546191.5	NEK6 Ensembl NCBI GeneCards UniProt Show fit	NIMA related kinase 6
chr8_-_17676484 Show fit	1.59	ENST00000634613.1 ENST00000519066.5	MTUS1 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated scaffold protein 1
chr12_+_52051402 Show fit	1.57	ENST00000243050.5 ENST00000550763.1 ENST00000394825.6 ENST00000394824.2 ENST00000548232.1 ENST00000562373.1	NR4A1 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 4 group A member 1
chr2_+_172821575 Show fit	1.35	ENST00000397087.7	RAPGEF4 Ensembl NCBI GeneCards UniProt Show fit	Rap guanine nucleotide exchange factor 4
chr1_+_89633086 Show fit	1.29	ENST00000370454.9	LRRC8C Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 8 VRAC subunit C
chr3_+_136022734 Show fit	1.21	ENST00000334546.6	PPP2R3A Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 2 regulatory subunit B''alpha
chr2_+_178320228 Show fit	1.15	ENST00000315022.2	OSBPL6 Ensembl NCBI GeneCards UniProt Show fit	oxysterol binding protein like 6
chr1_+_228208024 Show fit	1.13	ENST00000570156.7 ENST00000680850.1	OBSCN Ensembl NCBI GeneCards UniProt Show fit	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr6_-_75493773 Show fit	1.10	ENST00000237172.12	FILIP1 Ensembl NCBI GeneCards UniProt Show fit	filamin A interacting protein 1
chr13_-_44474296 Show fit	1.03	ENST00000611198.4	TSC22D1 Ensembl NCBI GeneCards UniProt Show fit	TSC22 domain family member 1
chr12_+_80099535 Show fit	0.97	ENST00000646859.1 ENST00000547103.7	OTOGL Ensembl NCBI GeneCards UniProt Show fit	otogelin like
chrX_+_136196750 Show fit	0.96	ENST00000539015.5	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr11_+_7576975 Show fit	0.95	ENST00000684215.1 ENST00000650027.1	PPFIBP2 Ensembl NCBI GeneCards UniProt Show fit	PPFIA binding protein 2
chrX_+_136197020 Show fit	0.90	ENST00000370676.7	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chrX_+_136197039 Show fit	0.89	ENST00000370683.6	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr15_-_52678560 Show fit	0.88	ENST00000562351.2 ENST00000261844.11 ENST00000399202.8 ENST00000562135.5	FAM214A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 214 member A
chr17_+_7855055 Show fit	0.88	ENST00000574668.1 ENST00000301599.7	TMEM88 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 88
chr2_+_148021404 Show fit	0.83	ENST00000638043.2	MBD5 Ensembl NCBI GeneCards UniProt Show fit	methyl-CpG binding domain protein 5
chr12_-_9115907 Show fit	0.81	ENST00000318602.12	A2M Ensembl NCBI GeneCards UniProt Show fit	alpha-2-macroglobulin
chr7_+_76302665 Show fit	0.77	ENST00000248553.7 ENST00000674638.1 ENST00000674547.1 ENST00000675226.1 ENST00000675538.1 ENST00000676231.1 ENST00000675134.1 ENST00000675906.1 ENST00000674650.1	HSPB1 Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family B (small) member 1
chr4_-_39638893 Show fit	0.76	ENST00000511809.5 ENST00000505729.1	SMIM14 Ensembl NCBI GeneCards UniProt Show fit	small integral membrane protein 14
chr1_-_145910031 Show fit	0.74	ENST00000369304.8	ITGA10 Ensembl NCBI GeneCards UniProt Show fit	integrin subunit alpha 10
chr7_+_74650224 Show fit	0.73	ENST00000652150.1 ENST00000650807.1	GTF2I Ensembl NCBI GeneCards UniProt Show fit	general transcription factor IIi
chr1_-_145910066 Show fit	0.73	ENST00000539363.2	ITGA10 Ensembl NCBI GeneCards UniProt Show fit	integrin subunit alpha 10
chr1_+_51729870 Show fit	0.71	ENST00000462759.5 ENST00000486942.5	OSBPL9 Ensembl NCBI GeneCards UniProt Show fit	oxysterol binding protein like 9
chr4_-_25863537 Show fit	0.69	ENST00000502949.5 ENST00000264868.9 ENST00000513691.1 ENST00000514872.1	SEL1L3 Ensembl NCBI GeneCards UniProt Show fit	SEL1L family member 3
chr11_+_9575496 Show fit	0.68	ENST00000681684.1	WEE1 Ensembl NCBI GeneCards UniProt Show fit	WEE1 G2 checkpoint kinase
chr6_+_135851681 Show fit	0.62	ENST00000308191.11	PDE7B Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 7B
chr9_-_33402449 Show fit	0.61	ENST00000377425.8	AQP7 Ensembl NCBI GeneCards UniProt Show fit	aquaporin 7
chr3_-_112641292 Show fit	0.60	ENST00000439685.6	CCDC80 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 80
chr2_+_178284907 Show fit	0.60	ENST00000409631.5	OSBPL6 Ensembl NCBI GeneCards UniProt Show fit	oxysterol binding protein like 6
chr4_-_137532452 Show fit	0.59	ENST00000412923.6 ENST00000511115.5 ENST00000344876.9 ENST00000507846.5 ENST00000510305.5 ENST00000611581.1	PCDH18 Ensembl NCBI GeneCards UniProt Show fit	protocadherin 18
chrX_-_120559889 Show fit	0.58	ENST00000371323.3	CUL4B Ensembl NCBI GeneCards UniProt Show fit	cullin 4B
chr2_+_108588286 Show fit	0.57	ENST00000332345.10	LIMS1 Ensembl NCBI GeneCards UniProt Show fit	LIM zinc finger domain containing 1
chr7_-_78489900 Show fit	0.55	ENST00000636039.1	MAGI2 Ensembl NCBI GeneCards UniProt Show fit	membrane associated guanylate kinase, WW and PDZ domain containing 2
chr20_+_58907981 Show fit	0.54	ENST00000656419.1	GNAS Ensembl NCBI GeneCards UniProt Show fit	GNAS complex locus
chr3_+_179653129 Show fit	0.52	ENST00000680008.1	USP13 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 13
chr10_-_60944132 Show fit	0.51	ENST00000337910.10	RHOBTB1 Ensembl NCBI GeneCards UniProt Show fit	Rho related BTB domain containing 1
chr14_-_93955577 Show fit	0.49	ENST00000555507.5	ASB2 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat and SOCS box containing 2
chr9_-_33402551 Show fit	0.49	ENST00000297988.6 ENST00000624075.3 ENST00000625032.1 ENST00000625109.3	AQP7 Ensembl NCBI GeneCards UniProt Show fit	aquaporin 7
chr1_-_58784035 Show fit	0.49	ENST00000371222.4	JUN Ensembl NCBI GeneCards UniProt Show fit	Jun proto-oncogene, AP-1 transcription factor subunit
chr12_+_101594849 Show fit	0.48	ENST00000547405.5 ENST00000452455.6 ENST00000392934.7 ENST00000547509.5 ENST00000361685.6 ENST00000549145.5 ENST00000361466.7 ENST00000553190.5 ENST00000545503.6 ENST00000536007.5 ENST00000541119.5 ENST00000551300.5 ENST00000550270.1	MYBPC1 Ensembl NCBI GeneCards UniProt Show fit	myosin binding protein C1
chr1_+_228208054 Show fit	0.47	ENST00000284548.16 ENST00000422127.5	OBSCN Ensembl NCBI GeneCards UniProt Show fit	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr10_-_3785179 Show fit	0.47	ENST00000469435.1	KLF6 Ensembl NCBI GeneCards UniProt Show fit	Kruppel like factor 6
chr19_+_1266653 Show fit	0.46	ENST00000586472.5 ENST00000589266.5	CIRBP Ensembl NCBI GeneCards UniProt Show fit	cold inducible RNA binding protein
chr12_+_53461015 Show fit	0.46	ENST00000553064.6 ENST00000547859.2	PCBP2 Ensembl NCBI GeneCards UniProt Show fit	poly(rC) binding protein 2
chr13_+_75804221 Show fit	0.46	ENST00000489941.6 ENST00000525373.5	LMO7 Ensembl NCBI GeneCards UniProt Show fit	LIM domain 7
chr21_-_33643926 Show fit	0.45	ENST00000438788.1	CRYZL1 Ensembl NCBI GeneCards UniProt Show fit	crystallin zeta like 1
chr9_+_5231413 Show fit	0.45	ENST00000239316.4	INSL4 Ensembl NCBI GeneCards UniProt Show fit	insulin like 4
chr3_-_157160751 Show fit	0.45	ENST00000461804.5	CCNL1 Ensembl NCBI GeneCards UniProt Show fit	cyclin L1
chr3_+_141387616 Show fit	0.43	ENST00000509883.5	ZBTB38 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 38
chr3_-_30894661 Show fit	0.42	ENST00000282538.10 ENST00000454381.3	GADL1 Ensembl NCBI GeneCards UniProt Show fit	glutamate decarboxylase like 1
chr9_-_72365198 Show fit	0.42	ENST00000376962.10 ENST00000376960.8	ZFAND5 Ensembl NCBI GeneCards UniProt Show fit	zinc finger AN1-type containing 5
chr2_+_33436304 Show fit	0.41	ENST00000402538.7	RASGRP3 Ensembl NCBI GeneCards UniProt Show fit	RAS guanyl releasing protein 3
chr9_+_68356899 Show fit	0.41	ENST00000396392.5	PGM5 Ensembl NCBI GeneCards UniProt Show fit	phosphoglucomutase 5
chr8_+_144107733 Show fit	0.40	ENST00000323662.9	WDR97 Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 97
chr2_+_148021083 Show fit	0.39	ENST00000642680.2	MBD5 Ensembl NCBI GeneCards UniProt Show fit	methyl-CpG binding domain protein 5
chr1_+_39215255 Show fit	0.39	ENST00000671089.1	MACF1 Ensembl NCBI GeneCards UniProt Show fit	microtubule actin crosslinking factor 1
chr2_+_108588453 Show fit	0.38	ENST00000393310.5	LIMS1 Ensembl NCBI GeneCards UniProt Show fit	LIM zinc finger domain containing 1
chr16_-_31428325 Show fit	0.38	ENST00000287490.5	COX6A2 Ensembl NCBI GeneCards UniProt Show fit	cytochrome c oxidase subunit 6A2
chr8_+_2045037 Show fit	0.38	ENST00000262113.9	MYOM2 Ensembl NCBI GeneCards UniProt Show fit	myomesin 2
chr12_+_40224956 Show fit	0.37	ENST00000298910.12 ENST00000343742.6	LRRK2 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat kinase 2
chr2_+_148021001 Show fit	0.37	ENST00000407073.5	MBD5 Ensembl NCBI GeneCards UniProt Show fit	methyl-CpG binding domain protein 5
chr22_-_50578417 Show fit	0.36	ENST00000312108.12 ENST00000395650.6	CPT1B Ensembl NCBI GeneCards UniProt Show fit	carnitine palmitoyltransferase 1B
chr3_+_159852933 Show fit	0.36	ENST00000482804.1	SCHIP1 Ensembl NCBI GeneCards UniProt Show fit	schwannomin interacting protein 1
chr8_-_93017656 Show fit	0.36	ENST00000520686.5	TRIQK Ensembl NCBI GeneCards UniProt Show fit	triple QxxK/R motif containing
chr8_+_2045058 Show fit	0.35	ENST00000523438.1	MYOM2 Ensembl NCBI GeneCards UniProt Show fit	myomesin 2
chr8_-_65789084 Show fit	0.35	ENST00000379419.8	PDE7A Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 7A
chr7_+_80602200 Show fit	0.35	ENST00000534394.5	CD36 Ensembl NCBI GeneCards UniProt Show fit	CD36 molecule
chr7_+_80602150 Show fit	0.33	ENST00000309881.11	CD36 Ensembl NCBI GeneCards UniProt Show fit	CD36 molecule
chr3_-_112641128 Show fit	0.33	ENST00000206423.8	CCDC80 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 80
chr16_+_11965193 Show fit	0.33	ENST00000053243.6 ENST00000396495.3	TNFRSF17 Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 17
chr20_+_34977625 Show fit	0.32	ENST00000618182.6	MYH7B Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 7B
chr1_+_26159071 Show fit	0.32	ENST00000374268.5	FAM110D Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 110 member D
chr13_+_111114550 Show fit	0.32	ENST00000317133.9	ARHGEF7 Ensembl NCBI GeneCards UniProt Show fit	Rho guanine nucleotide exchange factor 7
chr7_-_82443715 Show fit	0.32	ENST00000356253.9 ENST00000423588.1	CACNA2D1 Ensembl NCBI GeneCards UniProt Show fit	calcium voltage-gated channel auxiliary subunit alpha2delta 1
chr10_+_61901678 Show fit	0.31	ENST00000644638.1 ENST00000681100.1 ENST00000279873.12	ARID5B Ensembl NCBI GeneCards UniProt Show fit	AT-rich interaction domain 5B
chr8_+_141417902 Show fit	0.31	ENST00000681443.1	PTP4A3 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase 4A3
chr5_-_67196791 Show fit	0.30	ENST00000256447.5	CD180 Ensembl NCBI GeneCards UniProt Show fit	CD180 molecule
chr13_+_111186773 Show fit	0.30	ENST00000426073.6	ARHGEF7 Ensembl NCBI GeneCards UniProt Show fit	Rho guanine nucleotide exchange factor 7
chr6_-_2744126 Show fit	0.29	ENST00000647417.1	MYLK4 Ensembl NCBI GeneCards UniProt Show fit	myosin light chain kinase family member 4
chr4_-_39638846 Show fit	0.29	ENST00000295958.10	SMIM14 Ensembl NCBI GeneCards UniProt Show fit	small integral membrane protein 14
chr15_+_78266181 Show fit	0.29	ENST00000446172.2	DNAJA4 Ensembl NCBI GeneCards UniProt Show fit	DnaJ heat shock protein family (Hsp40) member A4
chr1_-_225999312 Show fit	0.29	ENST00000272091.8	SDE2 Ensembl NCBI GeneCards UniProt Show fit	SDE2 telomere maintenance homolog
chr1_+_202010575 Show fit	0.29	ENST00000367283.7 ENST00000367284.10	ELF3 Ensembl NCBI GeneCards UniProt Show fit	E74 like ETS transcription factor 3
chr7_-_105691637 Show fit	0.28	ENST00000472195.1	ATXN7L1 Ensembl NCBI GeneCards UniProt Show fit	ataxin 7 like 1
chr4_+_94451857 Show fit	0.28	ENST00000318007.9 ENST00000380180.7 ENST00000437932.5 ENST00000615540.4 ENST00000359265.8 ENST00000512274.1 ENST00000503974.5 ENST00000504489.3 ENST00000317968.9 ENST00000542407.5	PDLIM5 Ensembl NCBI GeneCards UniProt Show fit	PDZ and LIM domain 5
chr14_+_104724221 Show fit	0.27	ENST00000330877.7	ADSS1 Ensembl NCBI GeneCards UniProt Show fit	adenylosuccinate synthase 1
chr6_+_25726767 Show fit	0.27	ENST00000274764.5	H2BC1 Ensembl NCBI GeneCards UniProt Show fit	H2B clustered histone 1
chr17_+_7884783 Show fit	0.26	ENST00000380358.9	CHD3 Ensembl NCBI GeneCards UniProt Show fit	chromodomain helicase DNA binding protein 3
chr13_+_75804169 Show fit	0.26	ENST00000526371.1 ENST00000526528.1	LMO7 Ensembl NCBI GeneCards UniProt Show fit	LIM domain 7
chr3_+_113897470 Show fit	0.25	ENST00000440446.2 ENST00000488680.1	GRAMD1C Ensembl NCBI GeneCards UniProt Show fit	GRAM domain containing 1C
chr7_-_151187772 Show fit	0.25	ENST00000377867.7	ASB10 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat and SOCS box containing 10
chr5_-_138139382 Show fit	0.25	ENST00000265191.4	NME5 Ensembl NCBI GeneCards UniProt Show fit	NME/NM23 family member 5
chr3_+_179653032 Show fit	0.25	ENST00000680587.1 ENST00000681064.1 ENST00000263966.8 ENST00000681358.1 ENST00000679749.1	USP13 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 13
chr17_-_36196748 Show fit	0.25	ENST00000619989.1	CCL3L1 Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine ligand 3 like 1
chr11_-_19060706 Show fit	0.25	ENST00000329773.3	MRGPRX2 Ensembl NCBI GeneCards UniProt Show fit	MAS related GPR family member X2
chrX_-_129523436 Show fit	0.24	ENST00000371123.5 ENST00000371121.5 ENST00000371122.8	SMARCA1 Ensembl NCBI GeneCards UniProt Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr7_+_5879827 Show fit	0.24	ENST00000416608.5	OCM Ensembl NCBI GeneCards UniProt Show fit	oncomodulin
chr9_+_35341830 Show fit	0.24	ENST00000636694.1	UNC13B Ensembl NCBI GeneCards UniProt Show fit	unc-13 homolog B
chr7_-_113919000 Show fit	0.23	ENST00000284601.4	PPP1R3A Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory subunit 3A
chr3_+_52414523 Show fit	0.23	ENST00000461861.5	PHF7 Ensembl NCBI GeneCards UniProt Show fit	PHD finger protein 7
chrX_-_50643649 Show fit	0.23	ENST00000460112.3	SHROOM4 Ensembl NCBI GeneCards UniProt Show fit	shroom family member 4
chr10_-_102419934 Show fit	0.23	ENST00000406432.5	PSD Ensembl NCBI GeneCards UniProt Show fit	pleckstrin and Sec7 domain containing
chr1_+_203128279 Show fit	0.23	ENST00000367235.1 ENST00000618295.1	ADORA1 Ensembl NCBI GeneCards UniProt Show fit	adenosine A1 receptor
chr3_+_141387801 Show fit	0.23	ENST00000514251.5	ZBTB38 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 38
chr12_-_117968223 Show fit	0.22	ENST00000425217.5	KSR2 Ensembl NCBI GeneCards UniProt Show fit	kinase suppressor of ras 2
chr8_+_141416141 Show fit	0.22	ENST00000680615.1	PTP4A3 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase 4A3
chr11_+_1919694 Show fit	0.22	ENST00000278317.11 ENST00000453458.5 ENST00000381557.6 ENST00000381579.7 ENST00000381589.7 ENST00000381563.8 ENST00000344578.8 ENST00000381558.6	TNNT3 Ensembl NCBI GeneCards UniProt Show fit	troponin T3, fast skeletal type
chr8_-_42377227 Show fit	0.21	ENST00000220812.3	DKK4 Ensembl NCBI GeneCards UniProt Show fit	dickkopf WNT signaling pathway inhibitor 4
chr8_+_141416078 Show fit	0.21	ENST00000349124.3	PTP4A3 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase 4A3
chr7_+_18496269 Show fit	0.21	ENST00000432645.6	HDAC9 Ensembl NCBI GeneCards UniProt Show fit	histone deacetylase 9
chr17_+_39665340 Show fit	0.20	ENST00000578283.1 ENST00000309889.3	TCAP Ensembl NCBI GeneCards UniProt Show fit	titin-cap
chr5_-_11589019 Show fit	0.19	ENST00000511377.5	CTNND2 Ensembl NCBI GeneCards UniProt Show fit	catenin delta 2
chr19_-_49423441 Show fit	0.19	ENST00000270631.2	PTH2 Ensembl NCBI GeneCards UniProt Show fit	parathyroid hormone 2
chr14_-_20436161 Show fit	0.18	ENST00000636854.3	KLHL33 Ensembl NCBI GeneCards UniProt Show fit	kelch like family member 33
chr5_+_54455661 Show fit	0.18	ENST00000302005.3	HSPB3 Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family B (small) member 3
chr8_+_106270161 Show fit	0.18	ENST00000517566.7 ENST00000531443.6	OXR1 Ensembl NCBI GeneCards UniProt Show fit	oxidation resistance 1
chr4_+_85778681 Show fit	0.18	ENST00000395183.6	ARHGAP24 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 24
chr16_+_31214088 Show fit	0.18	ENST00000613872.1	TRIM72 Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 72
chr13_-_30306997 Show fit	0.18	ENST00000380617.7 ENST00000441394.1	KATNAL1 Ensembl NCBI GeneCards UniProt Show fit	katanin catalytic subunit A1 like 1
chr3_+_138348570 Show fit	0.18	ENST00000423968.7	MRAS Ensembl NCBI GeneCards UniProt Show fit	muscle RAS oncogene homolog
chr1_-_114780624 Show fit	0.17	ENST00000060969.6 ENST00000369528.9	SIKE1 Ensembl NCBI GeneCards UniProt Show fit	suppressor of IKBKE 1
chr12_-_51009264 Show fit	0.17	ENST00000545993.7	SLC11A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 11 member 2
chr10_-_44978789 Show fit	0.17	ENST00000448778.1 ENST00000298295.4	DEPP1 Ensembl NCBI GeneCards UniProt Show fit	DEPP1 autophagy regulator
chr4_+_128809684 Show fit	0.17	ENST00000226319.11 ENST00000511647.5	JADE1 Ensembl NCBI GeneCards UniProt Show fit	jade family PHD finger 1
chr10_-_102419693 Show fit	0.17	ENST00000611678.4	PSD Ensembl NCBI GeneCards UniProt Show fit	pleckstrin and Sec7 domain containing
chr10_+_86668501 Show fit	0.17	ENST00000623056.4 ENST00000263066.11 ENST00000429277.7 ENST00000361373.9 ENST00000372066.8 ENST00000372056.8 ENST00000623007.3	LDB3 Ensembl NCBI GeneCards UniProt Show fit	LIM domain binding 3
chr17_+_81395469 Show fit	0.17	ENST00000584436.7	BAHCC1 Ensembl NCBI GeneCards UniProt Show fit	BAH domain and coiled-coil containing 1
chr17_-_36090133 Show fit	0.16	ENST00000613922.2	CCL3 Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine ligand 3
chr8_+_75539862 Show fit	0.16	ENST00000396423.4	HNF4G Ensembl NCBI GeneCards UniProt Show fit	hepatocyte nuclear factor 4 gamma
chr1_+_63523490 Show fit	0.16	ENST00000371088.5	EFCAB7 Ensembl NCBI GeneCards UniProt Show fit	EF-hand calcium binding domain 7
chr16_+_31214111 Show fit	0.16	ENST00000322122.8	TRIM72 Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 72
chr5_+_132873660 Show fit	0.16	ENST00000296877.3	LEAP2 Ensembl NCBI GeneCards UniProt Show fit	liver enriched antimicrobial peptide 2
chr8_+_75539893 Show fit	0.15	ENST00000674002.1	HNF4G Ensembl NCBI GeneCards UniProt Show fit	hepatocyte nuclear factor 4 gamma
chr3_-_38029604 Show fit	0.15	ENST00000334661.5	PLCD1 Ensembl NCBI GeneCards UniProt Show fit	phospholipase C delta 1
chr17_-_65561640 Show fit	0.15	ENST00000618960.4 ENST00000307078.10	AXIN2 Ensembl NCBI GeneCards UniProt Show fit	axin 2
chr1_-_31373067 Show fit	0.15	ENST00000373713.7	FABP3 Ensembl NCBI GeneCards UniProt Show fit	fatty acid binding protein 3
chr13_+_75760362 Show fit	0.15	ENST00000534657.5	LMO7 Ensembl NCBI GeneCards UniProt Show fit	LIM domain 7
chr17_+_81395449 Show fit	0.15	ENST00000675386.2	BAHCC1 Ensembl NCBI GeneCards UniProt Show fit	BAH domain and coiled-coil containing 1
chrX_+_79144664 Show fit	0.15	ENST00000645147.2	GPR174 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 174
chr1_-_156490599 Show fit	0.15	ENST00000360595.7	MEF2D Ensembl NCBI GeneCards UniProt Show fit	myocyte enhancer factor 2D
chr4_-_142846275 Show fit	0.14	ENST00000513000.5 ENST00000509777.5 ENST00000503927.5	INPP4B Ensembl NCBI GeneCards UniProt Show fit	inositol polyphosphate-4-phosphatase type II B
chr7_-_151187212 Show fit	0.14	ENST00000420175.3 ENST00000275838.5	ASB10 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat and SOCS box containing 10
chr10_-_3785197 Show fit	0.14	ENST00000497571.6	KLF6 Ensembl NCBI GeneCards UniProt Show fit	Kruppel like factor 6
chr17_+_82229034 Show fit	0.13	ENST00000582743.6 ENST00000578684.6 ENST00000577650.6 ENST00000582715.1	SLC16A3 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 16 member 3
chr6_+_44227025 Show fit	0.13	ENST00000371708.1	SLC29A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 29 member 1 (Augustine blood group)
chr14_+_55580196 Show fit	0.13	ENST00000395314.8 ENST00000554567.1 ENST00000555498.5 ENST00000438792.6 ENST00000395308.5	KTN1 Ensembl NCBI GeneCards UniProt Show fit	kinectin 1
chr18_+_3252267 Show fit	0.13	ENST00000536605.1 ENST00000580887.5	MYL12A Ensembl NCBI GeneCards UniProt Show fit	myosin light chain 12A
chr18_-_21703688 Show fit	0.13	ENST00000584464.1 ENST00000578270.5	ABHD3 Ensembl NCBI GeneCards UniProt Show fit	abhydrolase domain containing 3, phospholipase
chr19_+_10013468 Show fit	0.12	ENST00000591589.3	RDH8 Ensembl NCBI GeneCards UniProt Show fit	retinol dehydrogenase 8
chr6_+_151807319 Show fit	0.12	ENST00000443427.5	ESR1 Ensembl NCBI GeneCards UniProt Show fit	estrogen receptor 1
chr10_-_14838003 Show fit	0.12	ENST00000465530.2	CDNF Ensembl NCBI GeneCards UniProt Show fit	cerebral dopamine neurotrophic factor
chr3_-_149792547 Show fit	0.11	ENST00000446160.7 ENST00000462519.3	ANKUB1 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat and ubiquitin domain containing 1
chr10_-_73655984 Show fit	0.11	ENST00000394810.3	SYNPO2L Ensembl NCBI GeneCards UniProt Show fit	synaptopodin 2 like
chr11_+_1839452 Show fit	0.11	ENST00000381906.5	TNNI2 Ensembl NCBI GeneCards UniProt Show fit	troponin I2, fast skeletal type
chr7_+_143316105 Show fit	0.11	ENST00000343257.7 ENST00000650516.1	CLCN1 Ensembl NCBI GeneCards UniProt Show fit	chloride voltage-gated channel 1
chr8_-_61689768 Show fit	0.11	ENST00000517847.6 ENST00000389204.8 ENST00000517661.5 ENST00000517903.5 ENST00000522603.5 ENST00000541428.5 ENST00000522349.5 ENST00000522835.5 ENST00000518306.5	ASPH Ensembl NCBI GeneCards UniProt Show fit	aspartate beta-hydroxylase
chr11_-_31804067 Show fit	0.11	ENST00000639548.1 ENST00000640125.1 ENST00000481563.6 ENST00000639079.1 ENST00000638762.1 ENST00000638346.1	PAX6 Ensembl NCBI GeneCards UniProt Show fit	paired box 6
chr10_-_95069489 Show fit	0.10	ENST00000371270.6 ENST00000535898.5 ENST00000623108.3	CYP2C8 Ensembl NCBI GeneCards UniProt Show fit	cytochrome P450 family 2 subfamily C member 8
chr3_+_138348592 Show fit	0.10	ENST00000621127.4 ENST00000494949.5	MRAS Ensembl NCBI GeneCards UniProt Show fit	muscle RAS oncogene homolog
chr15_+_40239420 Show fit	0.10	ENST00000560346.5	PAK6 Ensembl NCBI GeneCards UniProt Show fit	p21 (RAC1) activated kinase 6
chr10_+_116324440 Show fit	0.10	ENST00000333254.4	CCDC172 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 172
chr10_-_3785225 Show fit	0.10	ENST00000542957.1	KLF6 Ensembl NCBI GeneCards UniProt Show fit	Kruppel like factor 6
chr22_-_35617321 Show fit	0.09	ENST00000397326.7 ENST00000442617.1	MB Ensembl NCBI GeneCards UniProt Show fit	myoglobin
chr8_-_94553444 Show fit	0.09	ENST00000297591.10 ENST00000421249.2	VIRMA Ensembl NCBI GeneCards UniProt Show fit	vir like m6A methyltransferase associated
chr13_+_75760659 Show fit	0.09	ENST00000526202.5 ENST00000465261.6	LMO7 Ensembl NCBI GeneCards UniProt Show fit	LIM domain 7
chr1_-_206772484 Show fit	0.09	ENST00000423557.1	IL10 Ensembl NCBI GeneCards UniProt Show fit	interleukin 10
chr15_+_63597378 Show fit	0.09	ENST00000638704.2 ENST00000534939.2	FBXL22 Ensembl NCBI GeneCards UniProt Show fit	F-box and leucine rich repeat protein 22
chr4_-_86360039 Show fit	0.09	ENST00000515650.2 ENST00000641724.1 ENST00000641607.1 ENST00000641324.1 ENST00000641903.1 ENST00000395157.9 ENST00000641823.1 ENST00000641873.1 ENST00000641102.1 ENST00000641462.2 ENST00000641217.1 ENST00000642006.1 ENST00000641020.1 ENST00000641110.1 ENST00000639175.1 ENST00000641485.1 ENST00000641864.1 ENST00000641954.1 ENST00000641647.1 ENST00000641459.1 ENST00000641762.1 ENST00000641777.1 ENST00000641208.1 ENST00000642015.1 ENST00000641493.1 ENST00000642032.1 ENST00000641010.1 ENST00000641287.1 ENST00000641943.1 ENST00000642103.1 ENST00000641047.1 ENST00000641166.1 ENST00000641207.1	MAPK10 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase 10
chr15_+_42359454 Show fit	0.08	ENST00000349748.8 ENST00000318023.11 ENST00000397163.8	CAPN3 Ensembl NCBI GeneCards UniProt Show fit	calpain 3
chr3_+_54123452 Show fit	0.08	ENST00000620722.4 ENST00000490478.5	CACNA2D3 Ensembl NCBI GeneCards UniProt Show fit	calcium voltage-gated channel auxiliary subunit alpha2delta 3
chr14_+_39267377 Show fit	0.08	ENST00000556148.5 ENST00000348007.7	MIA2 Ensembl NCBI GeneCards UniProt Show fit	MIA SH3 domain ER export factor 2
chr17_-_81923532 Show fit	0.08	ENST00000392366.7	MAFG Ensembl NCBI GeneCards UniProt Show fit	MAF bZIP transcription factor G
chr4_-_139177185 Show fit	0.07	ENST00000394235.6	ELF2 Ensembl NCBI GeneCards UniProt Show fit	E74 like ETS transcription factor 2
chr5_-_16508990 Show fit	0.07	ENST00000399793.6	RETREG1 Ensembl NCBI GeneCards UniProt Show fit	reticulophagy regulator 1
chr15_+_40239042 Show fit	0.07	ENST00000558055.5 ENST00000455577.6	PAK6 Ensembl NCBI GeneCards UniProt Show fit	p21 (RAC1) activated kinase 6
chr13_+_75760431 Show fit	0.07	ENST00000321797.12	LMO7 Ensembl NCBI GeneCards UniProt Show fit	LIM domain 7
chr2_-_150487658 Show fit	0.07	ENST00000375734.6 ENST00000263895.9 ENST00000454202.5	RND3 Ensembl NCBI GeneCards UniProt Show fit	Rho family GTPase 3
chr7_+_142760398 Show fit	0.07	ENST00000632998.1	PRSS2 Ensembl NCBI GeneCards UniProt Show fit	serine protease 2
chr14_+_78403686 Show fit	0.07	ENST00000553631.1 ENST00000554719.5	NRXN3 Ensembl NCBI GeneCards UniProt Show fit	neurexin 3
chr1_+_23691742 Show fit	0.07	ENST00000374550.8 ENST00000643754.2	RPL11 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L11
chr11_-_86069811 Show fit	0.07	ENST00000531930.5 ENST00000528398.5	PICALM Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol binding clathrin assembly protein
chr3_-_39192584 Show fit	0.07	ENST00000340369.4 ENST00000421646.1 ENST00000396251.1	XIRP1 Ensembl NCBI GeneCards UniProt Show fit	xin actin binding repeat containing 1
chr5_+_141370236 Show fit	0.06	ENST00000576222.2 ENST00000618934.1	PCDHGB3 Ensembl NCBI GeneCards UniProt Show fit	protocadherin gamma subfamily B, 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.2	GO:0021986	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.7	2.2	GO:0030185	nitric oxide transport(GO:0030185) cerebrospinal fluid secretion(GO:0033326) cellular response to mercury ion(GO:0071288) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.7	2.1	GO:2000974	trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164) negative regulation of pro-B cell differentiation(GO:2000974)
0.3	0.8	GO:0001869	regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.3	1.6	GO:0060399	positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.2	7.2	GO:0003301	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2	1.6	GO:0043435	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.2	6.5	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.2	0.8	GO:0044313	protein K6-linked deubiquitination(GO:0044313)
0.2	0.5	GO:0035026	leading edge cell differentiation(GO:0035026) cellular response to potassium ion starvation(GO:0051365)
0.2	1.1	GO:0015793	glycerol transport(GO:0015793)
0.2	0.8	GO:0099640	axo-dendritic protein transport(GO:0099640)
0.1	0.7	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.1	0.4	GO:1903217	negative regulation of late endosome to lysosome transport(GO:1902823) regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.1	1.5	GO:0036309	protein localization to M-band(GO:0036309)
0.1	0.2	GO:0010808	positive regulation of synaptic vesicle priming(GO:0010808)
0.1	0.7	GO:2000332	response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1	0.2	GO:0070256	negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.1	1.0	GO:0019321	pentose metabolic process(GO:0019321)
0.1	0.3	GO:0086048	membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0	2.5	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.0	0.3	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
0.0	0.2	GO:0051799	negative regulation of hair follicle development(GO:0051799)
0.0	0.6	GO:1904424	regulation of GTP binding(GO:1904424)
0.0	0.7	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.7	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.4	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0	3.6	GO:1901222	regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0	1.6	GO:2000772	regulation of cellular senescence(GO:2000772)
0.0	0.2	GO:0015692	lead ion transport(GO:0015692)
0.0	2.8	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.5	GO:0040032	post-embryonic body morphogenesis(GO:0040032)
0.0	0.5	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.1	GO:0030886	regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) negative regulation of myeloid dendritic cell activation(GO:0030886) negative regulation of interferon-alpha production(GO:0032687)
0.0	1.8	GO:0043486	histone exchange(GO:0043486)
0.0	0.3	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.2	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0	0.6	GO:0070914	UV-damage excision repair(GO:0070914)
0.0	0.1	GO:0015862	uridine transport(GO:0015862)
0.0	0.5	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.0	0.1	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0	0.3	GO:0031507	heterochromatin assembly(GO:0031507)
0.0	0.1	GO:0042264	peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0	0.3	GO:0060056	mammary gland involution(GO:0060056)
0.0	0.2	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.2	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0	0.2	GO:0051013	microtubule severing(GO:0051013)
0.0	0.1	GO:0035879	plasma membrane lactate transport(GO:0035879)
0.0	1.0	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.1	GO:2000434	regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0	1.1	GO:0019933	cAMP-mediated signaling(GO:0019933)
0.0	0.5	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.1	GO:0002933	lipid hydroxylation(GO:0002933)
0.0	0.2	GO:0006228	UTP biosynthetic process(GO:0006228)
0.0	0.1	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.2	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.4	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.4	GO:0048745	smooth muscle tissue development(GO:0048745)
0.0	0.1	GO:0060068	vagina development(GO:0060068) prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.0	0.1	GO:0031444	slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0	0.3	GO:0006853	carnitine shuttle(GO:0006853)
0.0	0.1	GO:0060631	regulation of meiosis I(GO:0060631)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	2.2	GO:0020003	symbiont-containing vacuole(GO:0020003)
0.3	1.5	GO:0034680	integrin alpha10-beta1 complex(GO:0034680)
0.1	0.4	GO:0044753	amphisome(GO:0044753)
0.1	1.8	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.1	0.5	GO:0035976	AP1 complex(GO:0035976)
0.1	1.6	GO:0010369	chromocenter(GO:0010369)
0.1	0.6	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.6	GO:0000322	storage vacuole(GO:0000322)
0.0	0.2	GO:0070826	paraferritin complex(GO:0070826)
0.0	0.2	GO:0044305	calyx of Held(GO:0044305)
0.0	0.9	GO:0005614	interstitial matrix(GO:0005614)
0.0	1.2	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.2	GO:0016589	NURF complex(GO:0016589)
0.0	0.3	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.4	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	1.8	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.2	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	0.4	GO:0032982	myosin filament(GO:0032982)
0.0	6.0	GO:0030027	lamellipodium(GO:0030027)
0.0	0.1	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.0	0.5	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.1	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.0	0.1	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.1	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.8	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	2.2	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.3	0.8	GO:0019959	interleukin-8 binding(GO:0019959)
0.2	7.0	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.2	0.8	GO:0008426	protein kinase C inhibitor activity(GO:0008426)
0.2	1.1	GO:0015254	glycerol channel activity(GO:0015254)
0.2	1.5	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1	0.1	GO:0070538	oleic acid binding(GO:0070538)
0.1	0.4	GO:0004782	sulfinoalanine decarboxylase activity(GO:0004782)
0.1	0.4	GO:1904713	beta-catenin destruction complex binding(GO:1904713)
0.1	0.8	GO:1904288	BAT3 complex binding(GO:1904288)
0.1	2.3	GO:0031432	titin binding(GO:0031432)
0.1	0.7	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
0.1	0.7	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1	1.3	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.1	1.6	GO:0001222	transcription corepressor binding(GO:0001222)
0.1	0.5	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.1	2.2	GO:0046965	retinoid X receptor binding(GO:0046965)
0.1	0.4	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.1	0.5	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.1	0.5	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.1	2.5	GO:0015248	sterol transporter activity(GO:0015248)
0.1	1.0	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.2	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
0.0	0.1	GO:0052739	phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0	0.2	GO:0004698	calcium-dependent protein kinase C activity(GO:0004698)
0.0	0.5	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.0	0.2	GO:0015087	cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0	0.3	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.2	GO:0070699	type II activin receptor binding(GO:0070699)
0.0	0.5	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.2	GO:0030172	troponin C binding(GO:0030172)
0.0	0.6	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.9	GO:0001968	fibronectin binding(GO:0001968)
0.0	1.3	GO:0030552	cAMP binding(GO:0030552)
0.0	2.0	GO:0098531	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0	0.2	GO:0036310	annealing helicase activity(GO:0036310)
0.0	0.1	GO:0034875	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0	0.5	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.7	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.2	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.7	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	2.1	GO:0051087	chaperone binding(GO:0051087)
0.0	5.3	GO:0003714	transcription corepressor activity(GO:0003714)
0.0	0.1	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.0	0.1	GO:0004303	estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0	0.3	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0	0.4	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.4	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.7	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
2.1	PID FANCONI PATHWAY	Fanconi anemia pathway
1.5	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
1.5	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.5	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.7	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.7	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
1.6	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.8	ST P38 MAPK PATHWAY	p38 MAPK Pathway
1.5	PID ILK PATHWAY	Integrin-linked kinase signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.3	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	4.2	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	2.2	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.7	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.8	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	1.3	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	1.0	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.6	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	1.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.7	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.0	2.2	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0	0.5	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.4	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle

Results for MEF2C

Z-value: 0.63

Motif logo

Transcription factors associated with MEF2C

Activity-expression correlation:

Activity profile of MEF2C motif

Sorted Z-values of MEF2C motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MEF2C

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: