Project

Inflammatory response time course, HUVEC (Wada, 2009)

Navigation
Downloads

Results for MEF2D_MEF2A

Z-value: 0.63

Motif logo

logo of logo of

Transcription factors associated with MEF2D_MEF2A

Gene Symbol Gene ID Gene Info
MEF2D
ENSG00000116604.18 MEF2D
MEF2A
ENSG00000068305.17 MEF2A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MEF2Dhg38_v1_chr1_-_156500763_1565008510.395.7e-02Click!
MEF2Ahg38_v1_chr15_+_99566066_99566087-0.232.8e-01Click!

Activity profile of MEF2D_MEF2A motif

Sorted Z-values of MEF2D_MEF2A motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MEF2D_MEF2A

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr12_+_52051402 3.28 ENST00000243050.5
ENST00000550763.1
ENST00000394825.6
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
NR4A1
nuclear receptor subfamily 4 group A member 1
chr2_-_156342348 1.70 ENST00000409572.5
NR4A2
nuclear receptor subfamily 4 group A member 2
chr19_+_45469841 1.27 ENST00000592811.5
ENST00000586615.5
FOSB
FosB proto-oncogene, AP-1 transcription factor subunit
chr21_-_26843012 0.83 ENST00000517777.6
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr21_-_26843063 0.83 ENST00000678221.1
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr1_-_169734064 0.81 ENST00000333360.12
SELE
selectin E
chr6_+_135851681 0.79 ENST00000308191.11
PDE7B
phosphodiesterase 7B
chr4_-_148442342 0.73 ENST00000358102.8
NR3C2
nuclear receptor subfamily 3 group C member 2
chr18_+_23135452 0.71 ENST00000580153.5
ENST00000256925.12
CABLES1
Cdk5 and Abl enzyme substrate 1
chr12_+_12785652 0.70 ENST00000356591.5
APOLD1
apolipoprotein L domain containing 1
chr8_+_40153475 0.70 ENST00000315792.5
TCIM
transcriptional and immune response regulator
chr3_+_194136138 0.69 ENST00000232424.4
HES1
hes family bHLH transcription factor 1
chr2_-_207166818 0.66 ENST00000423015.5
KLF7
Kruppel like factor 7
chr5_+_54455661 0.60 ENST00000302005.3
HSPB3
heat shock protein family B (small) member 3
chr9_+_124291935 0.60 ENST00000546191.5
NEK6
NIMA related kinase 6
chr9_-_94593810 0.60 ENST00000375337.4
FBP2
fructose-bisphosphatase 2
chr2_+_238138661 0.58 ENST00000409223.2
KLHL30
kelch like family member 30
chr5_+_173889337 0.58 ENST00000520867.5
ENST00000334035.9
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr1_-_58784035 0.54 ENST00000371222.4
JUN
Jun proto-oncogene, AP-1 transcription factor subunit
chr5_-_111756245 0.53 ENST00000447165.6
NREP
neuronal regeneration related protein
chr2_-_105438503 0.52 ENST00000393352.7
ENST00000607522.1
FHL2
four and a half LIM domains 2
chr17_+_7855055 0.51 ENST00000574668.1
ENST00000301599.7
TMEM88
transmembrane protein 88
chr3_+_8501846 0.51 ENST00000454244.4
LMCD1
LIM and cysteine rich domains 1
chr7_-_41703062 0.50 ENST00000242208.5
INHBA
inhibin subunit beta A
chr11_-_19202004 0.50 ENST00000648719.1
CSRP3
cysteine and glycine rich protein 3
chr11_+_9575496 0.50 ENST00000681684.1
WEE1
WEE1 G2 checkpoint kinase
chr5_-_138139382 0.50 ENST00000265191.4
NME5
NME/NM23 family member 5
chr7_+_154305256 0.48 ENST00000619756.4
DPP6
dipeptidyl peptidase like 6
chr19_+_35138993 0.46 ENST00000612146.4
ENST00000589209.5
FXYD1
FXYD domain containing ion transport regulator 1
chr19_+_35139440 0.45 ENST00000455515.6
FXYD1
FXYD domain containing ion transport regulator 1
chr2_-_207165923 0.45 ENST00000309446.11
KLF7
Kruppel like factor 7
chr4_-_185775890 0.44 ENST00000437304.6
SORBS2
sorbin and SH3 domain containing 2
chr2_+_148021404 0.42 ENST00000638043.2
MBD5
methyl-CpG binding domain protein 5
chr10_-_3785197 0.42 ENST00000497571.6
KLF6
Kruppel like factor 6
chr1_+_84164962 0.41 ENST00000614872.4
ENST00000394839.6
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr13_+_108629605 0.41 ENST00000457511.7
MYO16
myosin XVI
chr9_+_113594118 0.40 ENST00000620489.1
RGS3
regulator of G protein signaling 3
chr11_+_7576975 0.40 ENST00000684215.1
ENST00000650027.1
PPFIBP2
PPFIA binding protein 2
chr2_+_33436304 0.40 ENST00000402538.7
RASGRP3
RAS guanyl releasing protein 3
chr10_-_3785179 0.39 ENST00000469435.1
KLF6
Kruppel like factor 6
chr7_-_151187772 0.39 ENST00000377867.7
ASB10
ankyrin repeat and SOCS box containing 10
chr10_-_3785225 0.39 ENST00000542957.1
KLF6
Kruppel like factor 6
chr8_-_69833338 0.38 ENST00000524945.5
SLCO5A1
solute carrier organic anion transporter family member 5A1
chr5_-_88883701 0.38 ENST00000636998.1
MEF2C
myocyte enhancer factor 2C
chr6_-_75493629 0.38 ENST00000393004.6
FILIP1
filamin A interacting protein 1
chr10_-_73655984 0.37 ENST00000394810.3
SYNPO2L
synaptopodin 2 like
chr20_+_43945677 0.37 ENST00000358131.5
TOX2
TOX high mobility group box family member 2
chr4_-_185775271 0.37 ENST00000430503.5
ENST00000319454.10
ENST00000450341.5
SORBS2
sorbin and SH3 domain containing 2
chr3_-_157160751 0.35 ENST00000461804.5
CCNL1
cyclin L1
chr8_+_2045037 0.34 ENST00000262113.9
MYOM2
myomesin 2
chr7_-_151187212 0.34 ENST00000420175.3
ENST00000275838.5
ASB10
ankyrin repeat and SOCS box containing 10
chr17_+_70169516 0.33 ENST00000243457.4
KCNJ2
potassium inwardly rectifying channel subfamily J member 2
chr11_-_31804067 0.33 ENST00000639548.1
ENST00000640125.1
ENST00000481563.6
ENST00000639079.1
ENST00000638762.1
ENST00000638346.1
PAX6
paired box 6
chr9_-_131276499 0.33 ENST00000372271.4
FAM78A
family with sequence similarity 78 member A
chr1_+_203128279 0.32 ENST00000367235.1
ENST00000618295.1
ADORA1
adenosine A1 receptor
chr3_+_8501807 0.32 ENST00000426878.2
ENST00000397386.7
ENST00000415597.5
ENST00000157600.8
LMCD1
LIM and cysteine rich domains 1
chr4_-_142305935 0.32 ENST00000511838.5
INPP4B
inositol polyphosphate-4-phosphatase type II B
chr8_+_2045058 0.30 ENST00000523438.1
MYOM2
myomesin 2
chr4_-_142305826 0.30 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase type II B
chrX_+_105948429 0.29 ENST00000540278.1
NRK
Nik related kinase
chr14_-_64942720 0.29 ENST00000557049.1
ENST00000389614.6
GPX2
glutathione peroxidase 2
chr14_-_64942783 0.28 ENST00000612794.1
GPX2
glutathione peroxidase 2
chr15_-_70702273 0.28 ENST00000558758.5
ENST00000379983.6
ENST00000560441.5
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr11_-_47378391 0.28 ENST00000227163.8
SPI1
Spi-1 proto-oncogene
chr2_+_167187364 0.27 ENST00000672671.1
XIRP2
xin actin binding repeat containing 2
chr22_+_25742141 0.27 ENST00000536101.5
ENST00000335473.12
ENST00000407587.6
MYO18B
myosin XVIIIB
chr11_-_47378527 0.27 ENST00000378538.8
SPI1
Spi-1 proto-oncogene
chr15_-_52652031 0.27 ENST00000546305.6
FAM214A
family with sequence similarity 214 member A
chr19_+_35138778 0.27 ENST00000351325.9
ENST00000586871.5
ENST00000592174.1
FXYD1
ENSG00000221857.7
FXYD domain containing ion transport regulator 1
novel transcript
chr1_+_34792990 0.27 ENST00000450137.1
ENST00000342280.5
GJA4
gap junction protein alpha 4
chr2_+_167187283 0.27 ENST00000409605.1
ENST00000409273.6
XIRP2
xin actin binding repeat containing 2
chr3_+_138348592 0.27 ENST00000621127.4
ENST00000494949.5
MRAS
muscle RAS oncogene homolog
chr7_-_37448845 0.27 ENST00000310758.9
ELMO1
engulfment and cell motility 1
chr3_-_30894661 0.26 ENST00000282538.10
ENST00000454381.3
GADL1
glutamate decarboxylase like 1
chr4_-_75902444 0.26 ENST00000286719.12
PPEF2
protein phosphatase with EF-hand domain 2
chr11_-_31803663 0.26 ENST00000638802.1
ENST00000638878.1
PAX6
paired box 6
chr16_+_31214088 0.26 ENST00000613872.1
TRIM72
tripartite motif containing 72
chr7_-_22220226 0.26 ENST00000420196.5
RAPGEF5
Rap guanine nucleotide exchange factor 5
chr10_-_73651013 0.26 ENST00000372873.8
SYNPO2L
synaptopodin 2 like
chr3_+_138348570 0.25 ENST00000423968.7
MRAS
muscle RAS oncogene homolog
chr1_-_145910031 0.25 ENST00000369304.8
ITGA10
integrin subunit alpha 10
chr1_-_145910066 0.25 ENST00000539363.2
ITGA10
integrin subunit alpha 10
chr11_-_31803620 0.25 ENST00000639006.1
PAX6
paired box 6
chr16_-_31428325 0.24 ENST00000287490.5
COX6A2
cytochrome c oxidase subunit 6A2
chr1_+_113979391 0.24 ENST00000393300.6
ENST00000369551.5
OLFML3
olfactomedin like 3
chr6_-_6006878 0.24 ENST00000244766.7
NRN1
neuritin 1
chr1_+_113979460 0.24 ENST00000320334.5
OLFML3
olfactomedin like 3
chr6_-_2744126 0.24 ENST00000647417.1
MYLK4
myosin light chain kinase family member 4
chr5_-_67196791 0.23 ENST00000256447.5
CD180
CD180 molecule
chr2_+_178284907 0.23 ENST00000409631.5
OSBPL6
oxysterol binding protein like 6
chr16_+_31214111 0.23 ENST00000322122.8
TRIM72
tripartite motif containing 72
chr11_-_47378494 0.22 ENST00000533030.1
SPI1
Spi-1 proto-oncogene
chr1_-_201421718 0.22 ENST00000367312.5
ENST00000555340.6
ENST00000361379.9
ENST00000622580.4
TNNI1
troponin I1, slow skeletal type
chr11_-_18012883 0.22 ENST00000530613.5
ENST00000532389.5
ENST00000529728.5
ENST00000532265.5
SERGEF
secretion regulating guanine nucleotide exchange factor
chr12_+_40224956 0.21 ENST00000298910.12
ENST00000343742.6
LRRK2
leucine rich repeat kinase 2
chr9_+_5450503 0.21 ENST00000381573.8
ENST00000381577.4
CD274
CD274 molecule
chr12_+_78864768 0.21 ENST00000261205.9
ENST00000457153.6
SYT1
synaptotagmin 1
chr12_-_21941225 0.20 ENST00000538350.5
ABCC9
ATP binding cassette subfamily C member 9
chr1_+_101238090 0.20 ENST00000475289.2
S1PR1
sphingosine-1-phosphate receptor 1
chr12_-_9115907 0.20 ENST00000318602.12
A2M
alpha-2-macroglobulin
chr1_+_228208024 0.20 ENST00000570156.7
ENST00000680850.1
OBSCN
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr11_-_19201976 0.19 ENST00000647990.1
ENST00000649235.1
ENST00000265968.9
ENST00000649842.1
CSRP3
cysteine and glycine rich protein 3
chr5_-_16508812 0.19 ENST00000683414.1
RETREG1
reticulophagy regulator 1
chr5_+_191477 0.19 ENST00000328278.4
LRRC14B
leucine rich repeat containing 14B
chr7_+_30911845 0.19 ENST00000652696.1
ENST00000311813.11
AQP1
aquaporin 1 (Colton blood group)
chr7_-_134459089 0.19 ENST00000285930.9
AKR1B1
aldo-keto reductase family 1 member B
chr9_-_33402449 0.19 ENST00000377425.8
AQP7
aquaporin 7
chr22_+_31093358 0.18 ENST00000404574.5
SMTN
smoothelin
chr5_-_16508951 0.18 ENST00000682628.1
RETREG1
reticulophagy regulator 1
chr9_-_83267230 0.18 ENST00000328788.5
FRMD3
FERM domain containing 3
chr4_-_142846275 0.18 ENST00000513000.5
ENST00000509777.5
ENST00000503927.5
INPP4B
inositol polyphosphate-4-phosphatase type II B
chrX_+_71301742 0.18 ENST00000373829.8
ENST00000538820.1
ITGB1BP2
integrin subunit beta 1 binding protein 2
chr5_-_16508858 0.18 ENST00000684456.1
RETREG1
reticulophagy regulator 1
chr1_-_156490599 0.18 ENST00000360595.7
MEF2D
myocyte enhancer factor 2D
chr17_+_7558296 0.18 ENST00000438470.5
ENST00000436057.5
TNFSF13
TNF superfamily member 13
chr1_-_25430147 0.17 ENST00000349320.7
RHCE
Rh blood group CcEe antigens
chr10_-_6062290 0.17 ENST00000256876.10
ENST00000379954.5
IL2RA
interleukin 2 receptor subunit alpha
chr3_+_35642159 0.17 ENST00000187397.8
ARPP21
cAMP regulated phosphoprotein 21
chr8_-_42501224 0.17 ENST00000520262.6
ENST00000517366.1
SLC20A2
solute carrier family 20 member 2
chr14_+_23372809 0.17 ENST00000397242.2
ENST00000329715.2
IL25
interleukin 25
chr12_+_6226136 0.17 ENST00000676764.1
ENST00000646407.1
CD9
CD9 molecule
chr20_+_46029165 0.16 ENST00000616201.4
ENST00000616202.4
ENST00000616933.4
ENST00000626937.2
SLC12A5
solute carrier family 12 member 5
chr8_-_21812320 0.16 ENST00000517328.5
GFRA2
GDNF family receptor alpha 2
chr1_-_223665685 0.16 ENST00000366872.10
CAPN8
calpain 8
chr6_+_27810041 0.16 ENST00000369163.3
H3C10
H3 clustered histone 10
chr8_-_13514821 0.16 ENST00000276297.9
DLC1
DLC1 Rho GTPase activating protein
chr18_+_3252208 0.16 ENST00000578562.6
MYL12A
myosin light chain 12A
chr13_+_75804169 0.16 ENST00000526371.1
ENST00000526528.1
LMO7
LIM domain 7
chr11_-_31803960 0.15 ENST00000640872.1
ENST00000639109.1
ENST00000638629.1
ENST00000639386.2
PAX6
paired box 6
chr14_+_103123452 0.15 ENST00000558056.1
ENST00000560869.6
TNFAIP2
TNF alpha induced protein 2
chr13_-_96994350 0.15 ENST00000298440.5
ENST00000543457.6
ENST00000541038.2
OXGR1
oxoglutarate receptor 1
chr5_-_142325001 0.15 ENST00000344120.4
ENST00000434127.3
SPRY4
sprouty RTK signaling antagonist 4
chr4_-_113761068 0.15 ENST00000342666.9
ENST00000514328.5
ENST00000515496.5
ENST00000508738.5
ENST00000379773.6
CAMK2D
calcium/calmodulin dependent protein kinase II delta
chr4_-_39638893 0.15 ENST00000511809.5
ENST00000505729.1
SMIM14
small integral membrane protein 14
chr20_+_46029206 0.15 ENST00000243964.7
SLC12A5
solute carrier family 12 member 5
chr5_-_42811884 0.15 ENST00000514985.6
ENST00000511224.5
ENST00000507920.5
ENST00000510965.1
SELENOP
selenoprotein P
chr10_-_6062349 0.15 ENST00000379959.8
IL2RA
interleukin 2 receptor subunit alpha
chr20_+_34977625 0.14 ENST00000618182.6
MYH7B
myosin heavy chain 7B
chr1_+_26021768 0.14 ENST00000374280.4
EXTL1
exostosin like glycosyltransferase 1
chrX_-_21758097 0.14 ENST00000379494.4
SMPX
small muscle protein X-linked
chr4_+_41360759 0.14 ENST00000508501.5
ENST00000512946.5
ENST00000313860.11
ENST00000512632.5
ENST00000512820.5
LIMCH1
LIM and calponin homology domains 1
chr12_+_80099535 0.14 ENST00000646859.1
ENST00000547103.7
OTOGL
otogelin like
chr19_-_49423441 0.14 ENST00000270631.2
PTH2
parathyroid hormone 2
chr17_-_41055211 0.14 ENST00000542910.1
ENST00000398477.1
KRTAP2-2
keratin associated protein 2-2
chr9_-_33402551 0.14 ENST00000297988.6
ENST00000624075.3
ENST00000625032.1
ENST00000625109.3
AQP7
aquaporin 7
chr5_-_157345645 0.14 ENST00000312349.5
FNDC9
fibronectin type III domain containing 9
chr1_+_202010575 0.13 ENST00000367283.7
ENST00000367284.10
ELF3
E74 like ETS transcription factor 3
chr6_+_151807319 0.13 ENST00000443427.5
ESR1
estrogen receptor 1
chr18_+_44680093 0.13 ENST00000426838.8
ENST00000677068.1
SETBP1
SET binding protein 1
chr14_+_99684283 0.13 ENST00000261835.8
CYP46A1
cytochrome P450 family 46 subfamily A member 1
chr3_-_196515315 0.13 ENST00000397537.3
SMCO1
single-pass membrane protein with coiled-coil domains 1
chr17_-_69244846 0.13 ENST00000269081.8
ABCA10
ATP binding cassette subfamily A member 10
chr15_-_82806054 0.13 ENST00000541889.1
ENST00000334574.12
ENST00000561368.1
FSD2
fibronectin type III and SPRY domain containing 2
chr20_+_45407207 0.13 ENST00000372712.6
DBNDD2
dysbindin domain containing 2
chr7_-_11832190 0.13 ENST00000423059.9
ENST00000617773.1
THSD7A
thrombospondin type 1 domain containing 7A
chr12_+_4269771 0.13 ENST00000676411.1
CCND2
cyclin D2
chr5_-_36151853 0.12 ENST00000296603.5
LMBRD2
LMBR1 domain containing 2
chr14_-_102238439 0.12 ENST00000522534.5
MOK
MOK protein kinase
chr13_-_44474296 0.12 ENST00000611198.4
TSC22D1
TSC22 domain family member 1
chr12_-_262828 0.12 ENST00000343164.9
ENST00000436453.1
ENST00000445055.6
ENST00000546319.5
SLC6A13
solute carrier family 6 member 13
chr16_-_71577082 0.12 ENST00000355962.5
TAT
tyrosine aminotransferase
chr15_+_84817346 0.12 ENST00000258888.6
ALPK3
alpha kinase 3
chr12_-_54973683 0.12 ENST00000532804.5
ENST00000531122.5
ENST00000533446.5
TESPA1
thymocyte expressed, positive selection associated 1
chr14_+_71586261 0.11 ENST00000358550.6
SIPA1L1
signal induced proliferation associated 1 like 1
chr4_+_118888918 0.11 ENST00000434046.6
SYNPO2
synaptopodin 2
chr17_+_7884783 0.11 ENST00000380358.9
CHD3
chromodomain helicase DNA binding protein 3
chr2_-_218831791 0.11 ENST00000439262.6
ENST00000430489.1
PRKAG3
protein kinase AMP-activated non-catalytic subunit gamma 3
chr15_+_80072559 0.11 ENST00000560228.5
ENST00000559835.5
ENST00000559775.5
ENST00000558688.5
ENST00000560392.5
ENST00000560976.5
ENST00000558272.5
ENST00000558390.5
ZFAND6
zinc finger AN1-type containing 6
chr2_+_112645930 0.11 ENST00000272542.8
SLC20A1
solute carrier family 20 member 1
chr20_+_1894145 0.11 ENST00000400068.7
SIRPA
signal regulatory protein alpha
chr1_+_212608628 0.11 ENST00000613954.4
ENST00000341491.9
ENST00000366985.5
ATF3
activating transcription factor 3
chr6_+_44227025 0.10 ENST00000371708.1
SLC29A1
solute carrier family 29 member 1 (Augustine blood group)
chrX_-_30309387 0.10 ENST00000378970.5
NR0B1
nuclear receptor subfamily 0 group B member 1
chr1_+_26159071 0.10 ENST00000374268.5
FAM110D
family with sequence similarity 110 member D
chr3_+_16884942 0.10 ENST00000615277.5
PLCL2
phospholipase C like 2
chr16_-_15643105 0.10 ENST00000548025.5
ENST00000551742.5
ENST00000396368.8
MARF1
meiosis regulator and mRNA stability factor 1
chr8_-_48921419 0.10 ENST00000020945.4
SNAI2
snail family transcriptional repressor 2
chr8_+_106270161 0.10 ENST00000517566.7
ENST00000531443.6
OXR1
oxidation resistance 1
chr8_+_73991345 0.10 ENST00000284818.7
ENST00000518893.1
LY96
lymphocyte antigen 96
chr2_+_178320228 0.10 ENST00000315022.2
OSBPL6
oxysterol binding protein like 6
chr17_+_7281711 0.10 ENST00000317370.13
ENST00000571308.5
SLC2A4
solute carrier family 2 member 4
chr16_+_8674605 0.10 ENST00000268251.13
ABAT
4-aminobutyrate aminotransferase
chr11_+_129375841 0.10 ENST00000281437.6
BARX2
BARX homeobox 2
chr7_-_124929938 0.10 ENST00000668382.1
ENST00000655761.1
ENST00000393329.5
POT1
protection of telomeres 1
chr1_+_89633086 0.10 ENST00000370454.9
LRRC8C
leucine rich repeat containing 8 VRAC subunit C
chr20_+_1894462 0.10 ENST00000622179.4
SIRPA
signal regulatory protein alpha
chr1_+_95117923 0.10 ENST00000455656.1
ENST00000604534.5
TLCD4
TLCD4-RWDD3
TLC domain containing 4
TLCD4-RWDD3 readthrough
chr16_-_15643024 0.10 ENST00000540441.6
MARF1
meiosis regulator and mRNA stability factor 1
chr6_+_7107941 0.10 ENST00000379938.7
ENST00000467782.5
ENST00000334984.10
ENST00000349384.10
RREB1
ras responsive element binding protein 1
chr21_-_36980789 0.10 ENST00000675307.1
ENST00000612277.4
HLCS
holocarboxylase synthetase
chr3_+_188947199 0.09 ENST00000433971.5
TPRG1
tumor protein p63 regulated 1
chr1_-_39672080 0.09 ENST00000235628.2
NT5C1A
5'-nucleotidase, cytosolic IA
chr15_+_78266181 0.09 ENST00000446172.2
DNAJA4
DnaJ heat shock protein family (Hsp40) member A4
chr10_+_69802424 0.09 ENST00000673802.2
ENST00000517713.5
ENST00000520133.5
ENST00000522165.5
ENST00000673641.2
ENST00000673628.2
COL13A1
collagen type XIII alpha 1 chain
chr18_-_55403682 0.09 ENST00000564228.5
ENST00000630828.2
TCF4
transcription factor 4
chrX_-_110440218 0.09 ENST00000372057.1
ENST00000372054.3
AMMECR1
GNG5P2
AMMECR nuclear protein 1
G protein subunit gamma 5 pseudogene 2
chr7_-_124929801 0.09 ENST00000653241.1
ENST00000664366.1
ENST00000446993.6
ENST00000654766.1
ENST00000357628.8
ENST00000609702.5
POT1
protection of telomeres 1
chr22_+_19723525 0.09 ENST00000366425.4
GP1BB
glycoprotein Ib platelet subunit beta
chr7_-_27662836 0.09 ENST00000265395.7
HIBADH
3-hydroxyisobutyrate dehydrogenase
chr18_+_13611764 0.09 ENST00000585931.5
LDLRAD4
low density lipoprotein receptor class A domain containing 4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.5 3.3 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.2 0.7 GO:0045608 trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164) negative regulation of pro-B cell differentiation(GO:2000974)
0.2 1.2 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.2 0.5 GO:0051365 leading edge cell differentiation(GO:0035026) cellular response to potassium ion starvation(GO:0051365)
0.2 0.5 GO:0060279 positive regulation of ovulation(GO:0060279)
0.2 0.8 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 0.6 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.1 0.5 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1 0.3 GO:0070256 negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.1 0.3 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.6 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 1.6 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 0.3 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 0.2 GO:1902823 negative regulation of late endosome to lysosome transport(GO:1902823) regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.1 0.6 GO:0061709 reticulophagy(GO:0061709)
0.1 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.5 GO:0097338 response to clozapine(GO:0097338)
0.1 0.2 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.2 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.1 0.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.2 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.1 0.2 GO:0072019 nitric oxide transport(GO:0030185) cerebrospinal fluid secretion(GO:0033326) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.1 0.2 GO:0019401 hexitol metabolic process(GO:0006059) alditol biosynthetic process(GO:0019401)
0.1 1.0 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.1 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 0.3 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.4 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 1.3 GO:0051412 response to corticosterone(GO:0051412)
0.0 0.3 GO:0015793 glycerol transport(GO:0015793)
0.0 0.5 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.6 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.0 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.8 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.8 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.1 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.0 0.3 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.5 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.7 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0009305 protein biotinylation(GO:0009305) histone biotinylation(GO:0071110)
0.0 0.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.6 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.2 GO:0030222 eosinophil differentiation(GO:0030222)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.1 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.2 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.1 GO:0044858 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.1 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.1 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.1 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.0 GO:0014813 skeletal muscle satellite cell commitment(GO:0014813)
0.0 0.1 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.0 0.2 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 0.0 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.0 0.2 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.6 GO:2000772 regulation of cellular senescence(GO:2000772)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.8 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.1 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.1 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.3 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.5 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.1 0.2 GO:0044753 amphisome(GO:0044753)
0.1 0.5 GO:0035976 AP1 complex(GO:0035976)
0.1 0.2 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 1.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.2 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.0 0.2 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.2 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0005592 collagen type XI trimer(GO:0005592)
0.0 0.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.6 GO:0010369 chromocenter(GO:0010369)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 0.8 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.3 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.1 0.3 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.1 0.2 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.1 0.8 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.7 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.2 GO:0019959 interleukin-8 binding(GO:0019959)
0.1 0.3 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 0.5 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.1 0.5 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.5 GO:0034711 inhibin binding(GO:0034711)
0.1 0.3 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 1.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.7 GO:0031433 telethonin binding(GO:0031433)
0.0 0.1 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.2 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.6 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 2.8 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.1 GO:0018271 biotin-[acetyl-CoA-carboxylase] ligase activity(GO:0004077) biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity(GO:0004078) biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity(GO:0004079) biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity(GO:0004080) biotin-protein ligase activity(GO:0018271)
0.0 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.1 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 1.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.7 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.2 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0008430 selenium binding(GO:0008430)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.0 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.3 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.5 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.5 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 1.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.7 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.5 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.5 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits