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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for MYBL2

Z-value: 0.99

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Transcription factors associated with MYBL2

Gene Symbol Gene ID Gene Info
ENSG00000101057.16 MYBL2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MYBL2hg38_v1_chr20_+_43667019_43667098,
hg38_v1_chr20_+_43667105_43667125
0.135.4e-01Click!

Activity profile of MYBL2 motif

Sorted Z-values of MYBL2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MYBL2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr4_-_16898619 2.26 ENST00000502640.5
ENST00000304523.10
ENST00000506732.1
LIM domain binding 2
chr16_-_30021288 2.20 ENST00000574405.5
double C2 domain alpha
chr4_+_42397473 2.11 ENST00000319234.5
shisa family member 3
chr10_+_35126791 2.10 ENST00000474362.5
ENST00000374721.7
cAMP responsive element modulator
chr10_+_35127023 1.73 ENST00000429130.7
ENST00000469949.6
ENST00000460270.5
cAMP responsive element modulator
chr1_+_61203496 1.63 ENST00000663597.1
nuclear factor I A
chr5_-_88883701 1.49 ENST00000636998.1
myocyte enhancer factor 2C
chr15_-_70702273 1.46 ENST00000558758.5
ENST00000379983.6
ENST00000560441.5
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr12_+_93571832 1.43 ENST00000549887.1
suppressor of cytokine signaling 2
chr9_+_2110354 1.42 ENST00000634772.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr11_+_62337424 1.40 ENST00000415229.6
ENST00000301776.9
ENST00000628829.2
ENST00000534571.5
ENST00000526096.2
asparaginase and isoaspartyl peptidase 1
chr12_+_93570969 1.37 ENST00000536696.6
suppressor of cytokine signaling 2
chr12_+_93571664 1.30 ENST00000622746.4
ENST00000548537.1
suppressor of cytokine signaling 2
chr2_-_55269038 1.24 ENST00000417363.5
ENST00000412530.1
ENST00000366137.6
ENST00000420637.5
mitochondrial translational initiation factor 2
chr7_-_129952631 1.18 ENST00000473814.6
ENST00000490974.1
ubiquitin conjugating enzyme E2 H
chr5_-_88883420 1.12 ENST00000437473.6
myocyte enhancer factor 2C
chr7_-_129952901 1.10 ENST00000472396.5
ENST00000355621.8
ubiquitin conjugating enzyme E2 H
chr20_+_43916142 1.06 ENST00000423191.6
ENST00000372999.5
TOX high mobility group box family member 2
chr13_-_44474296 1.03 ENST00000611198.4
TSC22 domain family member 1
chr16_+_4788411 1.00 ENST00000589327.5
small integral membrane protein 22
chr18_+_23135452 0.99 ENST00000580153.5
ENST00000256925.12
Cdk5 and Abl enzyme substrate 1
chr5_-_88883199 0.97 ENST00000514015.5
ENST00000503075.1
myocyte enhancer factor 2C
chr1_-_209806124 0.97 ENST00000367021.8
ENST00000542854.5
interferon regulatory factor 6
chr4_-_88158605 0.97 ENST00000237612.8
ATP binding cassette subfamily G member 2 (Junior blood group)
chr12_-_27014300 0.97 ENST00000535819.1
ENST00000543803.5
ENST00000535423.5
ENST00000539741.5
ENST00000343028.9
ENST00000545600.1
ENST00000543088.5
transmembrane 7 superfamily member 3
chr1_-_75611109 0.92 ENST00000370859.7
solute carrier family 44 member 5
chr4_-_158173004 0.90 ENST00000585682.6
golgi associated kinase 1B
chr14_-_38256074 0.89 ENST00000342213.3
C-type lectin domain containing 14A
chr17_+_63477052 0.89 ENST00000290866.10
ENST00000428043.5
angiotensin I converting enzyme
chr5_-_95081482 0.87 ENST00000312216.12
ENST00000512425.5
ENST00000505208.5
ENST00000429576.6
ENST00000508509.5
ENST00000510732.5
multiple C2 and transmembrane domain containing 1
chr9_-_76692181 0.85 ENST00000376717.6
ENST00000223609.10
prune homolog 2 with BCH domain
chr4_-_158173042 0.85 ENST00000592057.1
ENST00000393807.9
golgi associated kinase 1B
chr3_-_71305986 0.84 ENST00000647614.1
forkhead box P1
chrX_-_120560884 0.83 ENST00000404115.8
cullin 4B
chr2_+_47403116 0.82 ENST00000645506.1
ENST00000406134.5
ENST00000233146.7
mutS homolog 2
chr2_+_47403061 0.80 ENST00000543555.6
mutS homolog 2
chr12_-_70637405 0.80 ENST00000548122.2
ENST00000551525.5
ENST00000550358.5
ENST00000334414.11
protein tyrosine phosphatase receptor type B
chr16_-_10559135 0.79 ENST00000536829.1
epithelial membrane protein 2
chr12_-_14961256 0.79 ENST00000541380.5
Rho GDP dissociation inhibitor beta
chr14_+_54396964 0.78 ENST00000543789.6
ENST00000442975.6
ENST00000458126.6
ENST00000556102.6
ENST00000335183.11
cyclin dependent kinase inhibitor 3
chr14_+_64540734 0.77 ENST00000247207.7
heat shock protein family A (Hsp70) member 2
chr1_+_178725147 0.77 ENST00000367634.6
Ral GEF with PH domain and SH3 binding motif 2
chr11_-_130314575 0.77 ENST00000397753.5
zinc finger and BTB domain containing 44
chr14_+_54396949 0.77 ENST00000611205.4
cyclin dependent kinase inhibitor 3
chr8_+_95133940 0.76 ENST00000519516.1
pleckstrin homology and FYVE domain containing 2
chrX_-_117973579 0.76 ENST00000371878.5
kelch like family member 13
chr1_-_97920986 0.76 ENST00000370192.8
dihydropyrimidine dehydrogenase
chr14_+_54397021 0.75 ENST00000541304.5
cyclin dependent kinase inhibitor 3
chr11_-_130314686 0.74 ENST00000525842.5
zinc finger and BTB domain containing 44
chr12_+_8989535 0.71 ENST00000356986.8
killer cell lectin like receptor G1
chr8_-_92095627 0.71 ENST00000517919.5
ENST00000617740.4
ENST00000613302.4
ENST00000436581.6
ENST00000614812.4
ENST00000519847.5
RUNX1 partner transcriptional co-repressor 1
chr1_+_178725227 0.70 ENST00000367635.8
Ral GEF with PH domain and SH3 binding motif 2
chr2_-_69643152 0.70 ENST00000606389.7
AP2 associated kinase 1
chr3_+_15601720 0.69 ENST00000673620.1
biotinidase
chr9_+_12775012 0.69 ENST00000319264.4
leucine rich adaptor protein 1 like
chr22_+_50089879 0.68 ENST00000545383.5
ENST00000262794.10
Mov10 like RISC complex RNA helicase 1
chr20_+_43945677 0.68 ENST00000358131.5
TOX high mobility group box family member 2
chrX_-_120560947 0.68 ENST00000674137.11
ENST00000371322.11
ENST00000681090.1
cullin 4B
chr3_-_172523460 0.68 ENST00000420541.6
TNF superfamily member 10
chr3_-_165837412 0.67 ENST00000479451.5
ENST00000488954.1
ENST00000264381.8
butyrylcholinesterase
chr12_+_8989612 0.67 ENST00000266551.8
killer cell lectin like receptor G1
chr2_+_172735912 0.66 ENST00000409036.5
Rap guanine nucleotide exchange factor 4
chr2_-_221572272 0.66 ENST00000409854.5
ENST00000443796.5
ENST00000281821.7
EPH receptor A4
chr18_+_3448456 0.65 ENST00000549780.5
TGFB induced factor homeobox 1
chr9_+_34652167 0.65 ENST00000441545.7
ENST00000553620.5
interleukin 11 receptor subunit alpha
chr21_-_32612577 0.64 ENST00000673985.1
ENST00000382549.8
CFAP298-TCP10L readthrough
cilia and flagella associated protein 298
chr21_-_42010327 0.62 ENST00000398505.7
ENST00000449949.5
ENST00000310826.10
ENST00000398499.5
ENST00000398497.2
ENST00000398511.3
zinc finger and BTB domain containing 21
chr3_-_172523423 0.62 ENST00000241261.7
TNF superfamily member 10
chr20_+_64255728 0.62 ENST00000369758.8
ENST00000308824.11
ENST00000609372.1
ENST00000610196.1
ENST00000609764.1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr21_-_32612535 0.61 ENST00000673945.1
ENST00000458138.1
CFAP298-TCP10L readthrough
cilia and flagella associated protein 298
chr22_-_38506295 0.60 ENST00000403230.3
DEAD-box helicase 17
chr1_+_45583846 0.60 ENST00000437901.6
ENST00000537798.5
ENST00000350030.8
ENST00000527470.5
ENST00000525515.5
ENST00000528238.5
ENST00000470768.5
ENST00000372052.8
ENST00000629893.1
ENST00000351223.7
nuclear autoantigenic sperm protein
chr8_+_6708626 0.60 ENST00000285518.11
1-acylglycerol-3-phosphate O-acyltransferase 5
chr17_+_49788672 0.60 ENST00000454930.6
ENST00000259021.9
ENST00000509773.5
ENST00000510819.5
ENST00000424009.6
lysine acetyltransferase 7
chr17_-_41572052 0.59 ENST00000588431.1
ENST00000246662.9
keratin 9
chr6_-_56247525 0.59 ENST00000244728.10
collagen type XXI alpha 1 chain
chr2_-_69643615 0.59 ENST00000409068.5
AP2 associated kinase 1
chr9_-_70414657 0.58 ENST00000377126.4
Kruppel like factor 9
chr1_+_243256034 0.58 ENST00000366541.8
SHH signaling and ciliogenesis regulator SDCCAG8
chr17_-_55511434 0.58 ENST00000636752.1
small integral membrane protein 36
chr19_+_14529580 0.57 ENST00000215567.10
trans-2,3-enoyl-CoA reductase
chr2_+_172860038 0.56 ENST00000538974.5
ENST00000540783.5
Rap guanine nucleotide exchange factor 4
chr9_-_76906090 0.56 ENST00000376718.8
prune homolog 2 with BCH domain
chr21_-_32612339 0.55 ENST00000440966.5
ENST00000290155.8
cilia and flagella associated protein 298
chr3_-_112638097 0.55 ENST00000461431.1
coiled-coil domain containing 80
chr6_-_109690500 0.54 ENST00000448084.6
adenylate kinase 9
chr3_-_49429252 0.54 ENST00000615713.4
nicolin 1
chr2_-_55296361 0.54 ENST00000647547.1
coiled-coil domain containing 88A
chr3_+_48989876 0.54 ENST00000343546.8
prolyl 4-hydroxylase, transmembrane
chr3_+_48990219 0.53 ENST00000383729.9
prolyl 4-hydroxylase, transmembrane
chr13_+_34942263 0.53 ENST00000379939.7
ENST00000400445.7
neurobeachin
chr1_-_113759099 0.53 ENST00000393357.6
ENST00000446739.1
putative homeodomain transcription factor 1
chr1_+_212035717 0.52 ENST00000366991.5
denticleless E3 ubiquitin protein ligase homolog
chr2_+_172735838 0.52 ENST00000397081.8
Rap guanine nucleotide exchange factor 4
chr10_-_125158704 0.52 ENST00000531469.5
C-terminal binding protein 2
chr16_+_29812150 0.52 ENST00000647876.1
ENST00000567551.2
ENST00000567659.3
ENST00000637565.1
ENST00000358758.12
ENST00000636619.1
proline rich transmembrane protein 2
chr6_+_42050876 0.52 ENST00000465926.5
ENST00000482432.1
TATA-box binding protein associated factor 8
chr5_-_35230332 0.51 ENST00000504500.5
prolactin receptor
chr16_+_29812230 0.51 ENST00000300797.7
ENST00000637403.1
ENST00000572820.2
ENST00000637064.1
ENST00000636246.1
proline rich transmembrane protein 2
chr12_+_122527229 0.50 ENST00000450485.6
ENST00000333479.12
kinetochore associated 1
chr1_-_113759338 0.49 ENST00000369598.5
ENST00000369600.5
putative homeodomain transcription factor 1
chr12_-_110468222 0.49 ENST00000228827.8
ENST00000537466.6
ENST00000550974.1
GPN-loop GTPase 3
chr1_-_93847150 0.49 ENST00000370244.5
BCAR3 adaptor protein, NSP family member
chr14_+_104138578 0.48 ENST00000423312.7
kinesin family member 26A
chr1_-_54887161 0.48 ENST00000535035.6
ENST00000371269.9
ENST00000436604.2
24-dehydrocholesterol reductase
chr17_+_58692563 0.48 ENST00000461271.5
ENST00000583539.5
ENST00000337432.9
ENST00000421782.3
RAD51 paralog C
chr9_-_76906041 0.48 ENST00000443509.6
ENST00000428286.5
ENST00000376713.3
prune homolog 2 with BCH domain
chr19_-_39335999 0.48 ENST00000602185.5
ENST00000598034.5
ENST00000601387.5
ENST00000595636.1
ENST00000253054.12
ENST00000594700.5
ENST00000597595.6
glia maturation factor gamma
chr9_-_76394372 0.48 ENST00000376736.6
riboflavin kinase
chr4_-_87391149 0.47 ENST00000507286.1
ENST00000358290.9
hydroxysteroid 17-beta dehydrogenase 11
chr7_+_65873324 0.47 ENST00000434382.2
vitamin K epoxide reductase complex subunit 1 like 1
chr17_-_7261092 0.47 ENST00000574070.5
claudin 7
chr7_+_107168961 0.47 ENST00000468410.5
ENST00000478930.5
ENST00000464009.1
ENST00000222574.9
HMG-box transcription factor 1
chr5_+_175872741 0.47 ENST00000502265.5
complexin 2
chr17_+_76737387 0.47 ENST00000590393.1
ENST00000355954.7
ENST00000586689.5
ENST00000587661.5
ENST00000593181.5
ENST00000336509.8
major facilitator superfamily domain containing 11
chr12_+_103930600 0.46 ENST00000680316.1
ENST00000679861.1
heat shock protein 90 beta family member 1
chr1_-_108661055 0.46 ENST00000370031.5
ENST00000651461.1
ENST00000402983.5
ENST00000420055.1
HEN methyltransferase 1
chr1_-_154936681 0.46 ENST00000368467.4
phosphomevalonate kinase
chr9_-_36400860 0.45 ENST00000377877.4
ENST00000357058.7
ENST00000350199.8
ring finger protein 38
chr3_+_52410635 0.45 ENST00000327906.8
PHD finger protein 7
chr2_+_15940537 0.45 ENST00000281043.4
ENST00000638417.1
MYCN proto-oncogene, bHLH transcription factor
chr3_-_122793772 0.45 ENST00000306103.3
HSPB1 associated protein 1
chrX_-_141698739 0.45 ENST00000370515.3
SPANX family member D
chr1_+_65792889 0.45 ENST00000341517.9
phosphodiesterase 4B
chr7_-_73328082 0.45 ENST00000333149.7
tripartite motif containing 50
chr5_-_178627001 0.44 ENST00000611575.4
ENST00000520957.1
ENST00000316308.9
ENST00000611733.4
CDC like kinase 4
chr10_-_72626111 0.44 ENST00000604238.2
ENST00000642044.1
ENST00000635239.1
ENST00000398761.8
mitochondrial calcium uptake 1
chrX_-_150898779 0.44 ENST00000613030.4
ENST00000437787.6
CD99 molecule like 2
chr2_-_151261839 0.44 ENST00000331426.6
RNA binding motif protein 43
chr1_-_109393197 0.44 ENST00000538502.5
ENST00000482236.5
sortilin 1
chr20_+_36573589 0.43 ENST00000373872.9
ENST00000650844.1
TGFB induced factor homeobox 2
chr1_-_113759464 0.43 ENST00000357783.6
ENST00000369604.6
putative homeodomain transcription factor 1
chr1_-_160262522 0.43 ENST00000440682.5
DDB1 and CUL4 associated factor 8
chr1_-_160262501 0.43 ENST00000447377.5
DDB1 and CUL4 associated factor 8
chr17_-_34961448 0.43 ENST00000436961.7
ENST00000314144.10
chaperonin containing TCP1 subunit 6B
chr16_+_66552558 0.43 ENST00000345436.8
ENST00000351137.8
ENST00000362093.4
ENST00000264001.9
ENST00000417030.2
ENST00000527729.5
ENST00000532838.1
ENST00000615332.5
ENST00000616804.5
chemokine like factor
CKLF-CMTM1 readthrough
chr1_-_52055156 0.42 ENST00000371626.9
ENST00000610127.2
thioredoxin domain containing 12
chr3_+_69084929 0.42 ENST00000273258.4
ADP ribosylation factor like GTPase 6 interacting protein 5
chr17_-_34961400 0.42 ENST00000421975.7
chaperonin containing TCP1 subunit 6B
chr6_-_158819355 0.42 ENST00000367075.4
ezrin
chr12_-_96035571 0.42 ENST00000228740.7
leukotriene A4 hydrolase
chr9_+_113505256 0.42 ENST00000374136.5
regulator of G protein signaling 3
chr19_+_827823 0.41 ENST00000233997.4
azurocidin 1
chr1_+_203626813 0.41 ENST00000357681.10
ATPase plasma membrane Ca2+ transporting 4
chr17_+_50095331 0.41 ENST00000503176.6
pyruvate dehydrogenase kinase 2
chr19_-_55166565 0.41 ENST00000526003.5
ENST00000534170.5
ENST00000524407.7
dynein axonemal assembly factor 3
chr14_-_34713759 0.41 ENST00000673315.1
cofilin 2
chr19_-_55166671 0.40 ENST00000455045.5
dynein axonemal assembly factor 3
chr16_-_15888583 0.40 ENST00000575938.1
ENST00000573396.5
ENST00000573968.5
ENST00000255759.11
ENST00000575744.5
ENST00000573429.5
ENST00000575073.5
centrosomal protein 20
chr3_-_28348805 0.40 ENST00000457172.5
ENST00000479665.6
5-azacytidine induced 2
chr4_+_127880876 0.40 ENST00000270861.10
ENST00000515069.5
ENST00000513090.5
ENST00000507249.5
polo like kinase 4
chr19_-_55166632 0.39 ENST00000532817.5
ENST00000527223.6
ENST00000391720.8
dynein axonemal assembly factor 3
chr17_+_76738012 0.39 ENST00000590514.5
major facilitator superfamily domain containing 11
chr1_+_203626775 0.39 ENST00000367218.7
ATPase plasma membrane Ca2+ transporting 4
chr15_+_65530754 0.39 ENST00000566074.5
3-hydroxyacyl-CoA dehydratase 3
chr6_-_109690515 0.38 ENST00000532976.1
adenylate kinase 9
chr16_+_70294777 0.38 ENST00000563206.5
ENST00000451014.7
ENST00000568625.5
DEAD-box helicase 19B
chrX_+_77910656 0.38 ENST00000343533.9
ENST00000341514.11
ENST00000645454.1
ENST00000642651.1
ENST00000644362.1
ATPase copper transporting alpha
phosphoglycerate kinase 1
chr14_+_24232612 0.38 ENST00000560139.5
ENST00000559910.5
ENST00000348719.11
guanosine monophosphate reductase 2
chr7_+_80646436 0.38 ENST00000419819.2
CD36 molecule
chr2_-_55419821 0.37 ENST00000644630.1
ENST00000471947.2
ENST00000436346.7
ENST00000642200.1
ENST00000413716.7
ENST00000263630.13
ENST00000645072.1
coiled-coil domain containing 88A
chr9_+_89311187 0.37 ENST00000314355.7
CDC28 protein kinase regulatory subunit 2
chr2_+_189857393 0.37 ENST00000452382.1
PMS1 homolog 1, mismatch repair system component
chr14_-_75069478 0.37 ENST00000555463.1
acylphosphatase 1
chr7_+_80369547 0.37 ENST00000435819.5
CD36 molecule
chr8_+_95133746 0.37 ENST00000315367.4
pleckstrin homology and FYVE domain containing 2
chr2_-_55419565 0.37 ENST00000647341.1
ENST00000647401.1
ENST00000336838.10
ENST00000621814.4
ENST00000644033.1
ENST00000645477.1
ENST00000647517.1
coiled-coil domain containing 88A
chr3_+_44861883 0.37 ENST00000302392.5
transmembrane protein 42
chr6_+_27865308 0.37 ENST00000613174.2
H2A clustered histone 16
chr14_+_24232422 0.37 ENST00000620807.4
ENST00000355299.8
ENST00000559836.5
guanosine monophosphate reductase 2
chr17_+_64507029 0.36 ENST00000553412.5
centrosomal protein 95
chr3_+_28348695 0.36 ENST00000383768.7
zinc finger CW-type and PWWP domain containing 2
chrX_-_72239022 0.36 ENST00000373657.2
ENST00000334463.4
ERCC excision repair 6 like, spindle assembly checkpoint helicase
chr21_-_32612806 0.36 ENST00000673807.1
CFAP298-TCP10L readthrough
chr3_-_28348924 0.36 ENST00000414162.5
ENST00000420543.6
5-azacytidine induced 2
chr19_-_14529193 0.36 ENST00000596853.6
ENST00000676515.1
ENST00000678338.1
ENST00000595992.6
ENST00000677848.1
ENST00000677762.1
ENST00000678009.1
ENST00000596075.2
ENST00000601533.6
ENST00000396969.8
ENST00000598692.2
ENST00000678098.1
DnaJ heat shock protein family (Hsp40) member B1
chr14_+_24232892 0.36 ENST00000420554.6
guanosine monophosphate reductase 2
chr10_-_72626053 0.36 ENST00000603011.5
ENST00000361114.10
mitochondrial calcium uptake 1
chr10_+_35126923 0.35 ENST00000374726.7
cAMP responsive element modulator
chr9_-_123268538 0.35 ENST00000360998.3
ENST00000348403.10
spermatid perinuclear RNA binding protein
chr2_-_210476687 0.35 ENST00000233714.8
ENST00000443314.5
ENST00000441020.7
ENST00000450366.7
ENST00000431941.6
LanC like 1
chr3_-_3179674 0.35 ENST00000424814.5
ENST00000450014.1
ENST00000231948.9
ENST00000432408.6
ENST00000639284.1
cereblon
chr14_+_24232921 0.35 ENST00000557854.5
ENST00000399440.7
ENST00000559104.5
ENST00000456667.7
guanosine monophosphate reductase 2
chr20_-_54070520 0.35 ENST00000371435.6
ENST00000395961.7
brain enriched myelin associated protein 1
chrX_+_130339886 0.34 ENST00000543953.5
ENST00000612248.4
ENST00000424447.5
ENST00000545805.6
solute carrier family 25 member 14
chr5_+_136160986 0.34 ENST00000507637.1
SMAD family member 5
chr2_-_27489716 0.34 ENST00000260570.8
ENST00000675690.1
intraflagellar transport 172
chr5_+_36606355 0.34 ENST00000681909.1
ENST00000513903.5
ENST00000681795.1
ENST00000680125.1
ENST00000612708.5
ENST00000680232.1
ENST00000681776.1
ENST00000681926.1
ENST00000679958.1
ENST00000265113.9
ENST00000504121.5
ENST00000512374.1
ENST00000613445.5
ENST00000679983.1
solute carrier family 1 member 3
chr19_+_39296399 0.34 ENST00000333625.3
interferon lambda 1
chr13_+_52455972 0.34 ENST00000490903.5
ENST00000480747.1
cytoskeleton associated protein 2
chr5_+_139342442 0.34 ENST00000394795.6
ENST00000510080.1
poly(A) binding protein interacting protein 2
chr11_+_34052329 0.34 ENST00000530820.5
cell cycle associated protein 1
chrX_-_10620419 0.34 ENST00000380782.6
midline 1
chr8_-_92095598 0.34 ENST00000520724.5
ENST00000518844.5
RUNX1 partner transcriptional co-repressor 1
chr17_+_64506953 0.33 ENST00000580188.1
ENST00000556440.7
ENST00000581056.5
centrosomal protein 95
chr3_+_69084973 0.33 ENST00000478935.1
ADP ribosylation factor like GTPase 6 interacting protein 5
chr3_-_98522514 0.33 ENST00000503004.5
ENST00000506575.1
ENST00000513452.5
ENST00000515620.5
claudin domain containing 1
chr8_-_38468627 0.33 ENST00000683815.1
ENST00000684654.1
ENST00000447712.7
ENST00000397091.9
fibroblast growth factor receptor 1
chr16_+_69424634 0.33 ENST00000515314.6
ENST00000561792.6
ENST00000568237.1
cytochrome b5 type B
chr21_-_44817968 0.33 ENST00000397893.3
small ubiquitin like modifier 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.4 3.6 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.4 1.2 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.3 0.9 GO:0006186 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.3 1.5 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.3 0.8 GO:1903248 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.2 0.7 GO:0014016 neuroblast differentiation(GO:0014016)
0.2 0.7 GO:0019483 uracil catabolic process(GO:0006212) beta-alanine biosynthetic process(GO:0019483)
0.2 0.9 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.2 0.7 GO:0007037 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.2 0.7 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.2 1.3 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.2 1.0 GO:0044565 dendritic cell proliferation(GO:0044565)
0.2 0.6 GO:0072720 response to dithiothreitol(GO:0072720)
0.2 4.1 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.2 0.5 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.2 0.5 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.2 0.5 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
0.2 1.4 GO:0006528 asparagine metabolic process(GO:0006528)
0.2 0.5 GO:0031247 actin rod assembly(GO:0031247)
0.2 0.5 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.4 GO:0050720 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720)
0.1 0.8 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.3 GO:0036146 cellular response to mycotoxin(GO:0036146)
0.1 0.8 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 0.4 GO:0071284 copper ion export(GO:0060003) cellular response to lead ion(GO:0071284)
0.1 0.3 GO:0051039 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.1 0.5 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.1 0.4 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.7 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 1.2 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 0.4 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 0.3 GO:0007525 somatic muscle development(GO:0007525)
0.1 1.4 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 0.8 GO:0070836 caveola assembly(GO:0070836)
0.1 0.4 GO:1902896 terminal web assembly(GO:1902896)
0.1 1.0 GO:0015886 heme transport(GO:0015886)
0.1 0.7 GO:0070543 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.5 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1 0.8 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.4 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.1 0.4 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 1.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.6 GO:0051414 response to cortisol(GO:0051414)
0.1 0.6 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 1.6 GO:0072189 ureter development(GO:0072189)
0.1 0.5 GO:0006710 androgen catabolic process(GO:0006710)
0.1 2.2 GO:0010669 epithelial structure maintenance(GO:0010669)
0.1 0.6 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.2 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.1 4.7 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 0.4 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1 0.6 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 1.5 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.1 0.6 GO:0060125 habituation(GO:0046959) negative regulation of growth hormone secretion(GO:0060125)
0.1 0.2 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.1 0.5 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 1.4 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.1 0.3 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 1.5 GO:0006768 biotin metabolic process(GO:0006768)
0.1 0.2 GO:0070352 positive regulation of white fat cell proliferation(GO:0070352)
0.1 0.4 GO:0060467 negative regulation of fertilization(GO:0060467)
0.1 0.9 GO:0015871 choline transport(GO:0015871)
0.1 0.6 GO:0032466 negative regulation of cytokinesis(GO:0032466)
0.1 0.3 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.1 0.2 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 0.3 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.3 GO:0045345 positive regulation of MHC class I biosynthetic process(GO:0045345)
0.0 1.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 1.4 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.4 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.2 GO:1900737 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.0 0.1 GO:0019249 lactate biosynthetic process(GO:0019249)
0.0 0.3 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.9 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.7 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.2 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.9 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 1.4 GO:0044458 motile cilium assembly(GO:0044458)
0.0 2.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.5 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.4 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.2 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.6 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.1 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.6 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 2.0 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.4 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.3 GO:0006537 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.6 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.6 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.3 GO:0015793 glycerol transport(GO:0015793)
0.0 1.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 1.1 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.3 GO:0061525 hindgut development(GO:0061525)
0.0 0.1 GO:0097698 telomere maintenance via base-excision repair(GO:0097698)
0.0 0.5 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.3 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476)
0.0 0.1 GO:0006404 RNA import into nucleus(GO:0006404)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:1901253 regulation of dendritic cell cytokine production(GO:0002730) negative regulation of intracellular transport of viral material(GO:1901253)
0.0 0.6 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.5 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.5 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.5 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.0 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.2 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.0 1.0 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.2 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.5 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.0 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 3.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.6 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.5 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.2 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 1.1 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 0.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.6 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.0 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0 0.3 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.5 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.0 0.3 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.9 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.1 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.1 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.1 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.3 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.3 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.4 GO:0006293 nucleotide-excision repair, preincision complex stabilization(GO:0006293)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.3 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.0 0.1 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.4 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.5 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362) termination of RNA polymerase I transcription(GO:0006363)
0.0 1.2 GO:0006968 cellular defense response(GO:0006968)
0.0 0.9 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 0.1 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.2 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.1 GO:0044211 CTP salvage(GO:0044211)
0.0 0.3 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.3 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.1 GO:0051231 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 0.1 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.4 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.0 0.1 GO:0070944 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.0 1.3 GO:0017156 calcium ion regulated exocytosis(GO:0017156)
0.0 0.0 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.2 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0032301 MutSalpha complex(GO:0032301)
0.3 1.4 GO:1902560 GMP reductase complex(GO:1902560)
0.2 2.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.8 GO:1990246 uniplex complex(GO:1990246)
0.1 0.5 GO:1990423 RZZ complex(GO:1990423)
0.1 0.3 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.1 0.3 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.1 0.4 GO:0098592 microspike(GO:0044393) cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 0.5 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 0.3 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.4 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.6 GO:0071546 pi-body(GO:0071546)
0.1 0.5 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 0.5 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.5 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 1.4 GO:0071141 SMAD protein complex(GO:0071141)
0.1 1.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.6 GO:0036128 CatSper complex(GO:0036128)
0.1 0.5 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.1 0.3 GO:0043291 RAVE complex(GO:0043291)
0.1 0.6 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.3 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.2 GO:0072517 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.0 0.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 1.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.5 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0031673 H zone(GO:0031673)
0.0 0.4 GO:0042555 MCM complex(GO:0042555)
0.0 0.5 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.4 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.0 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.4 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.4 GO:0001741 XY body(GO:0001741)
0.0 0.6 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 2.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.4 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 1.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 1.0 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.6 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.6 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.5 GO:0097228 sperm principal piece(GO:0097228)
0.0 1.6 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.8 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 5.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0005838 proteasome regulatory particle(GO:0005838)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.4 1.4 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.3 1.7 GO:0032143 single thymine insertion binding(GO:0032143)
0.3 1.4 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.3 0.8 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.2 1.0 GO:0047708 biotinidase activity(GO:0047708)
0.2 0.9 GO:0035500 MH2 domain binding(GO:0035500)
0.2 0.6 GO:0000252 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity(GO:0047012)
0.2 3.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 0.6 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.2 3.6 GO:0003680 AT DNA binding(GO:0003680)
0.2 0.9 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 0.9 GO:0031711 tripeptidyl-peptidase activity(GO:0008240) peptidyl-dipeptidase activity(GO:0008241) bradykinin receptor binding(GO:0031711) metallodipeptidase activity(GO:0070573)
0.2 2.3 GO:0030274 LIM domain binding(GO:0030274)
0.2 1.2 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.2 0.7 GO:0003990 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.1 0.4 GO:0004008 copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682)
0.1 0.6 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.9 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 1.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.4 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 0.3 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.1 1.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.7 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.3 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.1 0.8 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.5 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 0.9 GO:0042731 PH domain binding(GO:0042731)
0.1 0.5 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.4 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 0.9 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.1 0.4 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 0.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.4 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.8 GO:0031386 protein tag(GO:0031386)
0.1 1.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.5 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 0.2 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 0.4 GO:0102344 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.1 0.7 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.4 GO:0050733 RS domain binding(GO:0050733)
0.0 0.3 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 1.6 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.5 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.2 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.3 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 1.0 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.7 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 2.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.5 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.2 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.5 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.5 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 2.2 GO:0030552 cAMP binding(GO:0030552)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.5 GO:0046790 virion binding(GO:0046790)
0.0 0.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 2.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0016807 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.6 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 2.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.1 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.4 GO:0043295 glutathione binding(GO:0043295)
0.0 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.2 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.2 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.5 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.9 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.0 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.3 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.7 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.1 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.2 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 1.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.4 GO:0016671 peptide disulfide oxidoreductase activity(GO:0015037) oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.5 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.1 GO:0004001 adenosine kinase activity(GO:0004001)
0.0 0.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 1.2 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.4 GO:0008494 translation activator activity(GO:0008494)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.5 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 4.0 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 4.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.3 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.6 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 1.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.4 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.4 PID E2F PATHWAY E2F transcription factor network
0.0 1.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.6 PID AURORA B PATHWAY Aurora B signaling
0.0 0.7 PID P75 NTR PATHWAY p75(NTR)-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.4 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 3.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 1.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 0.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 1.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.8 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.7 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.7 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.8 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.6 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 1.2 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production