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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for NFATC2_NFATC3

Z-value: 1.40

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Transcription factors associated with NFATC2_NFATC3

Gene Symbol Gene ID Gene Info
ENSG00000101096.20 NFATC2
ENSG00000072736.19 NFATC3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFATC2hg38_v1_chr20_-_51562829_515628530.386.1e-02Click!
NFATC3hg38_v1_chr16_+_68085861_680859680.386.4e-02Click!

Activity profile of NFATC2_NFATC3 motif

Sorted Z-values of NFATC2_NFATC3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NFATC2_NFATC3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr14_-_91946989 10.35 ENST00000556154.5
fibulin 5
chr4_+_41613476 8.94 ENST00000508466.1
LIM and calponin homology domains 1
chr4_+_41612892 8.67 ENST00000509454.5
ENST00000396595.7
ENST00000381753.8
LIM and calponin homology domains 1
chr14_-_91947383 7.23 ENST00000267620.14
fibulin 5
chr18_+_79395856 6.33 ENST00000253506.9
ENST00000591814.5
ENST00000427363.7
nuclear factor of activated T cells 1
chr1_+_81800906 5.60 ENST00000674393.1
ENST00000674208.1
adhesion G protein-coupled receptor L2
chr10_-_114684612 5.46 ENST00000533213.6
ENST00000369252.8
actin binding LIM protein 1
chrX_-_63785510 5.38 ENST00000437457.6
ENST00000374878.5
ENST00000623517.3
Cdc42 guanine nucleotide exchange factor 9
chr18_+_79395942 5.20 ENST00000397790.6
nuclear factor of activated T cells 1
chr3_-_18438767 4.57 ENST00000454909.6
SATB homeobox 1
chr3_-_142029108 4.53 ENST00000497579.5
transcription factor Dp-2
chr8_-_126557691 4.49 ENST00000652209.1
LRAT domain containing 2
chr3_+_152300135 4.19 ENST00000465907.6
ENST00000492948.5
ENST00000485509.5
ENST00000464596.5
muscleblind like splicing regulator 1
chr1_+_61081728 3.60 ENST00000371189.8
nuclear factor I A
chrX_-_19965142 3.60 ENST00000340625.3
BCLAF1 and THRAP3 family member 3
chr4_-_185812209 3.56 ENST00000393523.6
ENST00000393528.7
ENST00000449407.6
sorbin and SH3 domain containing 2
chr6_+_15246054 3.43 ENST00000341776.7
jumonji and AT-rich interaction domain containing 2
chr12_+_93572664 3.29 ENST00000551556.2
suppressor of cytokine signaling 2
chr10_-_114684457 3.16 ENST00000392955.7
actin binding LIM protein 1
chr7_-_120858066 3.13 ENST00000222747.8
tetraspanin 12
chr8_-_28386417 3.11 ENST00000521185.5
ENST00000520290.5
ENST00000344423.10
zinc finger protein 395
chr1_+_99646025 3.05 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
palmdelphin
chr12_-_9115907 3.03 ENST00000318602.12
alpha-2-macroglobulin
chr4_+_155667198 2.79 ENST00000296518.11
guanylate cyclase 1 soluble subunit alpha 1
chr15_-_70702273 2.79 ENST00000558758.5
ENST00000379983.6
ENST00000560441.5
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr4_+_155666963 2.78 ENST00000455639.6
guanylate cyclase 1 soluble subunit alpha 1
chr4_+_155666718 2.78 ENST00000621234.4
ENST00000511108.5
guanylate cyclase 1 soluble subunit alpha 1
chr4_+_155667096 2.76 ENST00000393832.7
guanylate cyclase 1 soluble subunit alpha 1
chr4_-_185956652 2.64 ENST00000355634.9
sorbin and SH3 domain containing 2
chr7_+_30852273 2.60 ENST00000509504.2
novel protein, MINDY4 and AQP1 readthrough
chr4_-_16898561 2.55 ENST00000515064.5
ENST00000441778.6
LIM domain binding 2
chr8_-_28386073 2.49 ENST00000523095.5
ENST00000522795.1
zinc finger protein 395
chr1_+_81800368 2.46 ENST00000674489.1
ENST00000674442.1
ENST00000674419.1
ENST00000674407.1
ENST00000674168.1
ENST00000674307.1
ENST00000674209.1
ENST00000370715.5
ENST00000370713.5
ENST00000319517.10
ENST00000627151.2
ENST00000370717.6
adhesion G protein-coupled receptor L2
chr12_-_50222348 2.40 ENST00000552823.5
ENST00000552909.5
LIM domain and actin binding 1
chr9_+_128566741 2.39 ENST00000630866.1
spectrin alpha, non-erythrocytic 1
chr21_-_34526850 2.31 ENST00000481448.5
ENST00000381132.6
regulator of calcineurin 1
chr6_+_116511626 2.29 ENST00000368599.4
calcium homeostasis modulator family member 5
chr1_+_60865259 2.29 ENST00000371191.5
nuclear factor I A
chr4_-_148442508 2.28 ENST00000625323.2
nuclear receptor subfamily 3 group C member 2
chr5_-_111758061 2.28 ENST00000509979.5
ENST00000513100.5
ENST00000508161.5
ENST00000455559.6
neuronal regeneration related protein
chr4_-_185956348 2.20 ENST00000431902.5
ENST00000284776.11
ENST00000415274.5
sorbin and SH3 domain containing 2
chr9_-_13165442 2.18 ENST00000542239.1
ENST00000538841.5
ENST00000433359.6
multiple PDZ domain crumbs cell polarity complex component
chr4_+_155666827 2.17 ENST00000511507.5
ENST00000506455.6
guanylate cyclase 1 soluble subunit alpha 1
chr8_+_69492793 2.16 ENST00000616868.1
ENST00000419716.7
ENST00000402687.9
sulfatase 1
chr7_-_120858303 2.14 ENST00000415871.5
ENST00000430985.1
tetraspanin 12
chr1_+_84144260 2.05 ENST00000370685.7
protein kinase cAMP-activated catalytic subunit beta
chr21_-_34526815 2.02 ENST00000492600.1
regulator of calcineurin 1
chr10_+_30434176 2.01 ENST00000263056.6
ENST00000375322.2
mitogen-activated protein kinase kinase kinase 8
chr3_-_112641292 2.01 ENST00000439685.6
coiled-coil domain containing 80
chr7_+_94394886 1.98 ENST00000297268.11
ENST00000620463.1
collagen type I alpha 2 chain
chr12_+_50925007 1.95 ENST00000332160.5
methyltransferase like 7A
chr8_+_97887903 1.92 ENST00000520016.5
matrilin 2
chr8_-_80874771 1.92 ENST00000327835.7
zinc finger protein 704
chr13_+_91398613 1.91 ENST00000377067.9
glypican 5
chr9_-_13175824 1.90 ENST00000545857.5
multiple PDZ domain crumbs cell polarity complex component
chr6_-_10414985 1.88 ENST00000466073.5
ENST00000498450.3
transcription factor AP-2 alpha
chr7_+_143222037 1.84 ENST00000408947.4
taste 2 receptor member 40
chr18_-_25352116 1.84 ENST00000584787.5
ENST00000538137.6
ENST00000361524.8
zinc finger protein 521
chr18_-_55403682 1.77 ENST00000564228.5
ENST00000630828.2
transcription factor 4
chr4_-_158159657 1.73 ENST00000590648.5
golgi associated kinase 1B
chr9_-_14321948 1.73 ENST00000635877.1
ENST00000636432.1
ENST00000646622.1
nuclear factor I B
chr3_-_171460063 1.72 ENST00000284483.12
ENST00000475336.5
ENST00000357327.9
ENST00000460047.5
ENST00000488470.5
ENST00000470834.5
TRAF2 and NCK interacting kinase
chr17_-_51260032 1.66 ENST00000586178.6
mbt domain containing 1
chr9_-_39288138 1.66 ENST00000297668.10
contactin associated protein family member 3
chr10_-_103452384 1.64 ENST00000369788.7
calcium homeostasis modulator family member 2
chr3_-_112641128 1.63 ENST00000206423.8
coiled-coil domain containing 80
chr12_+_78863962 1.62 ENST00000393240.7
synaptotagmin 1
chr13_+_79481468 1.60 ENST00000620924.1
Nedd4 family interacting protein 2
chr16_+_55509006 1.56 ENST00000262134.10
lysophosphatidylcholine acyltransferase 2
chr10_-_103452356 1.56 ENST00000260743.10
calcium homeostasis modulator family member 2
chr13_-_99016034 1.55 ENST00000448493.7
dedicator of cytokinesis 9
chr8_-_17697654 1.54 ENST00000297488.10
microtubule associated scaffold protein 1
chr10_+_30434021 1.54 ENST00000542547.5
mitogen-activated protein kinase kinase kinase 8
chr3_-_149333407 1.51 ENST00000470080.5
transmembrane 4 L six family member 18
chr4_-_158173042 1.50 ENST00000592057.1
ENST00000393807.9
golgi associated kinase 1B
chr3_+_25428233 1.50 ENST00000437042.6
ENST00000330688.9
retinoic acid receptor beta
chr14_+_63204859 1.49 ENST00000555125.1
ras homolog family member J
chr8_-_6563044 1.48 ENST00000338312.10
angiopoietin 2
chr4_+_185209577 1.47 ENST00000652585.1
sorting nexin 25
chr17_+_7834200 1.47 ENST00000448097.7
lysine demethylase 6B
chr11_+_128693887 1.46 ENST00000281428.12
Fli-1 proto-oncogene, ETS transcription factor
chr8_-_94262308 1.44 ENST00000297596.3
ENST00000396194.6
GTP binding protein overexpressed in skeletal muscle
chr5_-_111756245 1.44 ENST00000447165.6
neuronal regeneration related protein
chr15_-_52295792 1.42 ENST00000261839.12
myosin VC
chr10_+_92834594 1.41 ENST00000371552.8
exocyst complex component 6
chr10_+_92831153 1.41 ENST00000672817.1
exocyst complex component 6
chr15_+_96325935 1.40 ENST00000421109.6
nuclear receptor subfamily 2 group F member 2
chr1_-_246507237 1.40 ENST00000490107.6
SET and MYND domain containing 3
chr18_-_55422306 1.39 ENST00000566777.5
ENST00000626584.2
transcription factor 4
chr7_+_80135694 1.36 ENST00000457358.7
G protein subunit alpha i1
chr2_-_74440484 1.36 ENST00000305557.9
ENST00000233330.6
rhotekin
chrX_-_140784366 1.35 ENST00000674533.1
cerebellar degeneration related protein 1
chr6_-_73452124 1.35 ENST00000680833.1
cyclic GMP-AMP synthase
chr12_-_7695752 1.35 ENST00000329913.4
growth differentiation factor 3
chr7_+_102912983 1.35 ENST00000339431.9
ENST00000249377.4
leucine rich repeat containing 17
chr7_-_82443715 1.33 ENST00000356253.9
ENST00000423588.1
calcium voltage-gated channel auxiliary subunit alpha2delta 1
chr3_+_152299570 1.32 ENST00000485910.5
ENST00000463374.5
muscleblind like splicing regulator 1
chr12_+_78864768 1.31 ENST00000261205.9
ENST00000457153.6
synaptotagmin 1
chr9_-_14314519 1.30 ENST00000397581.6
nuclear factor I B
chr17_-_48610971 1.30 ENST00000239165.9
homeobox B7
chr1_+_85580751 1.29 ENST00000451137.7
cellular communication network factor 1
chr9_-_123184233 1.26 ENST00000447404.6
spermatid perinuclear RNA binding protein
chr17_-_68955332 1.23 ENST00000269080.6
ENST00000615593.4
ENST00000586539.6
ENST00000430352.6
ATP binding cassette subfamily A member 8
chr5_+_149581368 1.22 ENST00000333677.7
Rho guanine nucleotide exchange factor 37
chr16_-_3256587 1.22 ENST00000536379.5
ENST00000541159.5
ENST00000339854.8
ENST00000219596.6
MEFV innate immuity regulator, pyrin
chr11_-_89490715 1.22 ENST00000528341.5
NADPH oxidase 4
chr14_+_63204436 1.21 ENST00000316754.8
ras homolog family member J
chr20_+_35172046 1.21 ENST00000216968.5
protein C receptor
chr9_-_14300231 1.20 ENST00000636735.1
nuclear factor I B
chr14_+_64540734 1.19 ENST00000247207.7
heat shock protein family A (Hsp70) member 2
chr3_-_65622073 1.18 ENST00000621418.4
ENST00000611645.4
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr9_-_70869076 1.18 ENST00000677594.1
transient receptor potential cation channel subfamily M member 3
chrX_-_117973717 1.18 ENST00000262820.7
kelch like family member 13
chr4_-_158173004 1.18 ENST00000585682.6
golgi associated kinase 1B
chr2_-_182522703 1.16 ENST00000410103.1
phosphodiesterase 1A
chr1_+_153776596 1.14 ENST00000458027.5
solute carrier family 27 member 3
chr5_+_141223332 1.14 ENST00000239449.7
ENST00000624896.1
ENST00000624396.1
protocadherin beta 14
novel protein
chr13_+_79481446 1.14 ENST00000487865.5
Nedd4 family interacting protein 2
chr18_-_55402187 1.13 ENST00000630268.2
ENST00000570177.6
transcription factor 4
chr12_-_91179472 1.12 ENST00000550099.5
ENST00000546391.5
decorin
chr18_-_55422492 1.12 ENST00000561992.5
ENST00000630712.2
transcription factor 4
chr1_-_54887161 1.12 ENST00000535035.6
ENST00000371269.9
ENST00000436604.2
24-dehydrocholesterol reductase
chr1_-_85404494 1.11 ENST00000633113.1
dimethylarginine dimethylaminohydrolase 1
chrX_-_117973579 1.11 ENST00000371878.5
kelch like family member 13
chr2_+_200440649 1.08 ENST00000366118.2
spermatogenesis associated serine rich 2 like
chr3_+_111859284 1.08 ENST00000498699.5
pleckstrin homology like domain family B member 2
chr9_-_94593810 1.08 ENST00000375337.4
fructose-bisphosphatase 2
chr8_-_17676484 1.05 ENST00000634613.1
ENST00000519066.5
microtubule associated scaffold protein 1
chr16_+_30000944 1.03 ENST00000562291.2
INO80 complex subunit E
chr12_-_52192007 1.02 ENST00000394815.3
keratin 80
chr2_-_55334529 1.02 ENST00000645860.1
ENST00000642563.1
ENST00000647396.1
coiled-coil domain containing 88A
chr5_+_140848360 1.01 ENST00000532602.2
protocadherin alpha 9
chr4_-_69860138 0.99 ENST00000226444.4
sulfotransferase family 1E member 1
chr3_-_15798184 0.98 ENST00000624145.3
ankyrin repeat domain 28
chr11_+_102112445 0.96 ENST00000524575.5
Yes1 associated transcriptional regulator
chr7_+_92057602 0.95 ENST00000491695.2
A-kinase anchoring protein 9
chr1_+_66534082 0.93 ENST00000683257.1
ENST00000684083.1
ENST00000682938.1
ENST00000683581.1
ENST00000682293.1
SH3GL interacting endocytic adaptor 1
chr1_+_66534171 0.92 ENST00000682762.1
ENST00000424320.6
SH3GL interacting endocytic adaptor 1
chr1_+_66534107 0.92 ENST00000371037.9
ENST00000684651.1
SH3GL interacting endocytic adaptor 1
chr1_-_68232514 0.92 ENST00000262348.9
ENST00000370973.2
ENST00000370971.1
Wnt ligand secretion mediator
chr3_-_15797930 0.92 ENST00000683139.1
ankyrin repeat domain 28
chr20_+_43945677 0.91 ENST00000358131.5
TOX high mobility group box family member 2
chr22_-_28712136 0.91 ENST00000464581.6
checkpoint kinase 2
chr5_-_42811884 0.90 ENST00000514985.6
ENST00000511224.5
ENST00000507920.5
ENST00000510965.1
selenoprotein P
chr1_+_66534014 0.90 ENST00000684664.1
ENST00000682416.1
ENST00000683499.1
SH3GL interacting endocytic adaptor 1
chr6_+_85449584 0.90 ENST00000369651.7
5'-nucleotidase ecto
chr17_-_48613468 0.90 ENST00000498634.2
homeobox B8
chr5_-_54310545 0.88 ENST00000504924.6
ENST00000620747.4
ENST00000507646.2
ENST00000502271.5
ADP ribosylation factor like GTPase 15
chr9_+_121299793 0.88 ENST00000373818.8
gelsolin
chr12_-_104050112 0.88 ENST00000547583.1
ENST00000546851.1
ENST00000360814.9
glycosyltransferase 8 domain containing 2
chr3_+_8501807 0.87 ENST00000426878.2
ENST00000397386.7
ENST00000415597.5
ENST00000157600.8
LIM and cysteine rich domains 1
chr17_+_7884783 0.87 ENST00000380358.9
chromodomain helicase DNA binding protein 3
chr2_-_73293538 0.87 ENST00000436467.4
ENST00000545030.1
early growth response 4
chr1_+_66533948 0.87 ENST00000684178.1
SH3GL interacting endocytic adaptor 1
chr22_-_28711931 0.86 ENST00000434810.5
ENST00000456369.5
checkpoint kinase 2
chr13_+_39038347 0.85 ENST00000379599.6
ENST00000379600.8
NHL repeat containing 3
chr9_-_13279407 0.85 ENST00000546205.5
multiple PDZ domain crumbs cell polarity complex component
chr4_+_133149307 0.85 ENST00000618019.1
protocadherin 10
chr12_-_58920465 0.84 ENST00000320743.8
leucine rich repeats and immunoglobulin like domains 3
chr10_-_60944132 0.84 ENST00000337910.10
Rho related BTB domain containing 1
chr7_-_151057848 0.84 ENST00000297518.4
cyclin dependent kinase 5
chr11_-_83071819 0.83 ENST00000524635.1
ENST00000526205.5
ENST00000533486.5
ENST00000533276.6
ENST00000527633.6
RAB30, member RAS oncogene family
chr8_+_39913881 0.82 ENST00000518237.6
indoleamine 2,3-dioxygenase 1
chr12_+_82686889 0.82 ENST00000321196.8
transmembrane O-mannosyltransferase targeting cadherins 2
chr3_-_27722699 0.82 ENST00000461503.2
eomesodermin
chr20_-_10420737 0.82 ENST00000649912.1
novel protein
chr12_-_52191981 0.82 ENST00000313234.9
keratin 80
chr7_-_151057880 0.81 ENST00000485972.6
cyclin dependent kinase 5
chr18_-_55351977 0.81 ENST00000643689.1
transcription factor 4
chrX_-_10576901 0.80 ENST00000380779.5
midline 1
chr3_-_157160751 0.80 ENST00000461804.5
cyclin L1
chrX_+_136648214 0.79 ENST00000370628.2
CD40 ligand
chr13_+_39038292 0.79 ENST00000470258.5
NHL repeat containing 3
chr18_-_55589770 0.78 ENST00000565018.6
ENST00000636400.2
transcription factor 4
chr6_-_52994248 0.76 ENST00000457564.1
ENST00000370960.5
glutathione S-transferase alpha 4
chr18_-_55589836 0.76 ENST00000537578.5
ENST00000564403.6
transcription factor 4
chr18_-_55401751 0.75 ENST00000537856.7
transcription factor 4
chr1_+_161721563 0.74 ENST00000367948.6
Fc receptor like B
chr16_+_1078781 0.74 ENST00000293897.5
somatostatin receptor 5
chr1_+_213988501 0.73 ENST00000261454.8
ENST00000435016.2
prospero homeobox 1
chr1_+_966466 0.73 ENST00000379410.8
ENST00000379407.7
ENST00000379409.6
pleckstrin homology domain containing N1
chr6_+_155216637 0.73 ENST00000275246.11
TIAM Rac1 associated GEF 2
chr3_+_111859180 0.73 ENST00000412622.5
ENST00000431670.7
pleckstrin homology like domain family B member 2
chr5_+_62412755 0.72 ENST00000325324.11
importin 11
chr13_+_45464995 0.71 ENST00000617493.1
component of oligomeric golgi complex 3
chrX_+_136648138 0.70 ENST00000370629.7
CD40 ligand
chr5_+_38846002 0.70 ENST00000274276.8
oncostatin M receptor
chr9_-_16870702 0.70 ENST00000380667.6
ENST00000545497.5
ENST00000486514.5
basonuclin 2
chr18_-_500692 0.69 ENST00000400256.5
collectin subfamily member 12
chr14_+_24232422 0.69 ENST00000620807.4
ENST00000355299.8
ENST00000559836.5
guanosine monophosphate reductase 2
chr18_-_55589795 0.69 ENST00000568740.5
ENST00000629387.2
transcription factor 4
chr20_-_17558811 0.69 ENST00000536626.7
ENST00000377868.6
beaded filament structural protein 1
chr19_+_41003946 0.68 ENST00000593831.1
cytochrome P450 family 2 subfamily B member 6
chr2_+_172860038 0.68 ENST00000538974.5
ENST00000540783.5
Rap guanine nucleotide exchange factor 4
chr12_-_70637405 0.68 ENST00000548122.2
ENST00000551525.5
ENST00000550358.5
ENST00000334414.11
protein tyrosine phosphatase receptor type B
chr6_-_112254647 0.67 ENST00000455073.1
ENST00000522006.5
ENST00000519932.5
laminin subunit alpha 4
chr16_+_15434577 0.67 ENST00000300006.9
bMERB domain containing 1
chr5_-_138875290 0.67 ENST00000521094.2
ENST00000274711.7
leucine rich repeat transmembrane neuronal 2
chr1_+_247416149 0.67 ENST00000366497.6
ENST00000391828.8
NLR family pyrin domain containing 3
chr11_-_76669985 0.67 ENST00000407242.6
ENST00000421973.1
leucine rich repeat containing 32

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 17.6 GO:0048251 elastic fiber assembly(GO:0048251)
1.0 3.0 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
1.0 2.9 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.7 2.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.6 2.5 GO:0003409 optic cup structural organization(GO:0003409)
0.6 1.8 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.5 1.5 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.5 1.0 GO:1902823 negative regulation of late endosome to lysosome transport(GO:1902823)
0.5 1.4 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.4 1.6 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.4 4.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.4 1.5 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.4 1.4 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.4 1.4 GO:0009956 radial pattern formation(GO:0009956)
0.3 1.0 GO:0006711 estrogen catabolic process(GO:0006711)
0.3 4.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.3 1.2 GO:1904045 cellular response to aldosterone(GO:1904045)
0.3 4.5 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.3 0.9 GO:0010607 negative regulation of cytoplasmic mRNA processing body assembly(GO:0010607)
0.3 2.1 GO:0097338 response to clozapine(GO:0097338)
0.3 1.4 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.3 1.1 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.3 1.6 GO:2001184 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.3 8.3 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.3 16.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.2 1.7 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.2 3.4 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.2 1.3 GO:0048859 formation of anatomical boundary(GO:0048859)
0.2 0.7 GO:2000724 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.2 0.6 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.2 0.8 GO:0032474 otolith morphogenesis(GO:0032474)
0.2 1.1 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.2 0.6 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.2 0.8 GO:0036269 swimming behavior(GO:0036269)
0.2 1.2 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.2 1.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.2 1.1 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.2 2.8 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.2 1.7 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 1.4 GO:0048539 bone marrow development(GO:0048539)
0.2 0.9 GO:0044858 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.2 0.5 GO:1904437 antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428) regulation of iron ion transport(GO:0034756) positive regulation of iron ion transport(GO:0034758) regulation of iron ion transmembrane transport(GO:0034759) positive regulation of iron ion transmembrane transport(GO:0034761) cellular response to iron(III) ion(GO:0071283) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.2 1.4 GO:2000321 positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.2 5.3 GO:0072189 ureter development(GO:0072189)
0.2 1.0 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.2 0.5 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.2 0.5 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.2 1.0 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.2 2.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2 0.2 GO:0032831 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.2 1.1 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.2 0.9 GO:0006196 AMP catabolic process(GO:0006196) adenosine biosynthetic process(GO:0046086)
0.2 0.5 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.7 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 0.4 GO:1902617 response to fluoride(GO:1902617)
0.1 2.0 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.4 GO:0071931 positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931)
0.1 0.4 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.1 3.1 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 5.1 GO:0010842 retina layer formation(GO:0010842)
0.1 0.3 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 1.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.5 GO:1900228 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.1 0.9 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.1 0.4 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.6 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.1 0.6 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.1 0.6 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.3 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.1 4.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 1.1 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.7 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.1 0.5 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.6 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 5.1 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.1 0.4 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.1 1.1 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.5 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.6 GO:0032431 activation of phospholipase A2 activity(GO:0032431)
0.1 1.3 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 1.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.2 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.1 0.4 GO:0035645 posterior midgut development(GO:0007497) enteric smooth muscle cell differentiation(GO:0035645)
0.1 1.9 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.6 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.1 2.5 GO:0010669 epithelial structure maintenance(GO:0010669)
0.1 1.4 GO:0006527 arginine catabolic process(GO:0006527)
0.1 0.2 GO:0036304 umbilical cord morphogenesis(GO:0036304) umbilical cord development(GO:0061027)
0.1 0.5 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.1 0.5 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 0.2 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.3 GO:1904550 positive regulation of transforming growth factor beta3 production(GO:0032916) chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.1 0.9 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 0.4 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.1 0.3 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.1 0.5 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.1 8.9 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 1.2 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.7 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 0.8 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.1 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.1 0.3 GO:0035989 tendon development(GO:0035989)
0.1 0.5 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.7 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.2 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.1 0.3 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.1 0.3 GO:1903786 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.1 0.3 GO:0035548 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) negative regulation of CD8-positive, alpha-beta T cell activation(GO:2001186) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.1 0.5 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 1.5 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 0.3 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.1 0.3 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.1 0.1 GO:2000910 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.1 1.0 GO:0042908 xenobiotic transport(GO:0042908)
0.1 0.4 GO:1903392 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.1 0.4 GO:0035063 nuclear speck organization(GO:0035063)
0.1 1.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.2 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 0.5 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.1 0.5 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.1 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.2 GO:0035627 ceramide transport(GO:0035627)
0.1 0.5 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 0.7 GO:0070307 lens fiber cell development(GO:0070307)
0.1 0.2 GO:0008614 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819)
0.1 0.8 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.6 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 1.1 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.1 3.5 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.3 GO:1902745 positive regulation of lamellipodium organization(GO:1902745) positive regulation of lamellipodium morphogenesis(GO:2000394)
0.1 2.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.3 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1 0.7 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 1.2 GO:0043101 purine-containing compound salvage(GO:0043101)
0.1 0.2 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.7 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.5 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.1 GO:0019087 transformation of host cell by virus(GO:0019087)
0.0 0.1 GO:0044546 NLRP3 inflammasome complex assembly(GO:0044546)
0.0 0.1 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.0 0.1 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0 0.9 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 13.7 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 1.0 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.3 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.5 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.6 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.6 GO:0060044 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0 2.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.7 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 7.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.4 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.2 GO:0071389 cellular response to mineralocorticoid stimulus(GO:0071389)
0.0 0.3 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.4 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.3 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.0 0.4 GO:0015747 urate transport(GO:0015747)
0.0 6.6 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.4 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.0 0.9 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.5 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.1 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.6 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 8.8 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 0.2 GO:0070305 response to cGMP(GO:0070305)
0.0 0.4 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.6 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.4 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.8 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.3 GO:0009642 response to light intensity(GO:0009642)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 2.5 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 0.4 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0065001 negative regulation of histone H3-K36 methylation(GO:0000415) specification of axis polarity(GO:0065001)
0.0 0.1 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:0001781 neutrophil apoptotic process(GO:0001781)
0.0 0.4 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.6 GO:0016180 snRNA processing(GO:0016180)
0.0 0.2 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 4.8 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.2 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.8 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.5 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0032470 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) positive regulation of endoplasmic reticulum calcium ion concentration(GO:0032470)
0.0 2.4 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 1.3 GO:0031102 neuron projection regeneration(GO:0031102)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 3.3 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.4 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.3 GO:0048535 lymph node development(GO:0048535)
0.0 0.4 GO:0044849 estrous cycle(GO:0044849)
0.0 0.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.5 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.2 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.3 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0 0.7 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.4 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.1 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.4 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.0 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.0 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.0 0.9 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.5 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.2 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.8 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0 0.1 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.0 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.2 GO:0035855 megakaryocyte development(GO:0035855)
0.0 1.5 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191) vesicle uncoating(GO:0072319)
0.0 0.1 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.0 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.7 GO:0008542 visual learning(GO:0008542)
0.0 0.2 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.4 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 17.6 GO:0071953 elastic fiber(GO:0071953)
0.6 2.9 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.4 2.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.3 1.0 GO:0044753 amphisome(GO:0044753)
0.3 1.0 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.2 1.2 GO:1902560 GMP reductase complex(GO:1902560)
0.2 0.9 GO:0044307 dendritic branch(GO:0044307)
0.2 4.9 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.2 5.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.2 0.5 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.2 2.7 GO:0008091 spectrin(GO:0008091)
0.1 1.2 GO:0072687 meiotic spindle(GO:0072687)
0.1 4.1 GO:0005614 interstitial matrix(GO:0005614)
0.1 1.1 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.1 0.6 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1 0.8 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 1.8 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.4 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 3.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 2.2 GO:0045180 basal cortex(GO:0045180)
0.1 1.3 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 3.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.5 GO:0031905 early endosome lumen(GO:0031905)
0.1 0.6 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 2.4 GO:0000145 exocyst(GO:0000145)
0.1 1.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 2.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 1.1 GO:0030478 actin cap(GO:0030478)
0.1 0.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 1.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 7.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.4 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.7 GO:0044327 dendritic spine head(GO:0044327)
0.1 0.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 5.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 2.4 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 0.7 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.6 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.1 0.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.0 0.6 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 19.6 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.6 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.6 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 1.6 GO:0051233 spindle midzone(GO:0051233)
0.0 0.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 1.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.6 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.3 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.4 GO:0005915 zonula adherens(GO:0005915)
0.0 0.4 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 1.2 GO:0005605 basal lamina(GO:0005605)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.3 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 1.0 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 6.3 GO:0030018 Z disc(GO:0030018)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.8 GO:1990752 microtubule end(GO:1990752)
0.0 0.9 GO:0099738 cell cortex region(GO:0099738)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 3.8 GO:0005795 Golgi stack(GO:0005795)
0.0 2.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0042641 actomyosin(GO:0042641)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 1.7 GO:0045095 keratin filament(GO:0045095)
0.0 3.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 2.5 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.6 GO:0098576 lumenal side of membrane(GO:0098576)
0.0 1.3 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.6 GO:0002102 podosome(GO:0002102)
0.0 1.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.2 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.3 GO:0005776 autophagosome(GO:0005776)
0.0 0.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 8.1 GO:0016524 latrotoxin receptor activity(GO:0016524)
1.7 11.8 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
1.4 5.8 GO:0001069 regulatory region RNA binding(GO:0001069)
1.0 3.0 GO:0019959 interleukin-8 binding(GO:0019959)
0.6 1.7 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.5 11.0 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.5 1.5 GO:0005174 CD40 receptor binding(GO:0005174)
0.5 2.9 GO:0030348 syntaxin-3 binding(GO:0030348)
0.5 4.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.4 2.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.4 3.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.4 1.6 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.4 1.1 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.3 8.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.3 0.8 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.3 1.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.3 1.0 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.2 1.7 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2 1.2 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.2 1.4 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 2.4 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.2 0.6 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.2 5.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 0.6 GO:0030290 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.2 0.6 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.2 2.4 GO:0030274 LIM domain binding(GO:0030274)
0.2 0.9 GO:0004882 androgen receptor activity(GO:0004882)
0.2 0.5 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.2 1.0 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.2 1.7 GO:0051525 NFAT protein binding(GO:0051525)
0.2 0.5 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.7 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 2.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.1 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 1.4 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 0.6 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 1.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 2.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.5 GO:0043273 CTPase activity(GO:0043273)
0.1 0.5 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1 0.3 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.1 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 1.7 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.4 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 3.7 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.6 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.8 GO:0045159 myosin II binding(GO:0045159)
0.1 0.5 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 3.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.7 GO:0005534 galactose binding(GO:0005534)
0.1 0.5 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 1.0 GO:0008430 selenium binding(GO:0008430)
0.1 0.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.6 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 2.8 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.2 GO:0000035 acyl binding(GO:0000035)
0.1 1.0 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 1.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 1.0 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 13.4 GO:0005178 integrin binding(GO:0005178)
0.1 1.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 1.6 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 2.7 GO:0032452 histone demethylase activity(GO:0032452)
0.1 0.6 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.9 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 1.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.5 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 0.3 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 0.3 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.1 0.4 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.3 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.4 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 1.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.5 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.4 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.2 GO:0035939 microsatellite binding(GO:0035939)
0.1 1.0 GO:0051393 alpha-actinin binding(GO:0051393)
0.1 0.5 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 0.2 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.1 1.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.4 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.3 GO:0004517 nitric-oxide synthase activity(GO:0004517) tetrahydrobiopterin binding(GO:0034617)
0.1 0.7 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 1.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.6 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.5 GO:0050692 DBD domain binding(GO:0050692)
0.1 7.5 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.1 1.0 GO:0043422 protein kinase B binding(GO:0043422)
0.1 3.1 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.3 GO:1990254 keratin filament binding(GO:1990254)
0.0 8.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.0 0.3 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.2 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.4 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.6 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 1.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.3 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.1 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.9 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.0 0.2 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.4 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.9 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.3 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 1.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.3 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.1 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 19.3 GO:0003779 actin binding(GO:0003779)
0.0 0.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.4 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 1.5 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.7 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.4 GO:0070878 primary miRNA binding(GO:0070878)
0.0 0.4 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.9 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.0 0.2 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.1 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.2 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.0 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 4.3 GO:0008017 microtubule binding(GO:0008017)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 7.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.2 GO:0010181 FMN binding(GO:0010181)
0.0 0.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.0 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 3.3 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.9 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.0 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.5 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 14.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 3.6 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 11.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 4.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 9.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 2.9 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 0.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 8.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 2.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 1.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 2.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 2.9 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 16.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.7 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 0.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 2.1 PID IL3 PATHWAY IL3-mediated signaling events
0.1 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.2 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 4.7 PID E2F PATHWAY E2F transcription factor network
0.0 2.1 PID ATM PATHWAY ATM pathway
0.0 1.4 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 2.3 PID AURORA B PATHWAY Aurora B signaling
0.0 3.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.6 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.9 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.9 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.5 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.2 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.2 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.8 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.2 12.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 2.0 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 2.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 2.9 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 1.4 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.1 4.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 4.7 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 1.8 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 2.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 7.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 3.4 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 3.9 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.1 0.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 1.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.9 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 1.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.6 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.1 4.2 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 0.9 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME CD28 CO STIMULATION Genes involved in CD28 co-stimulation
0.0 0.5 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 1.1 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.9 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.9 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
0.0 0.8 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.8 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.4 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.6 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 1.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.5 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.6 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.6 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 1.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin